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Conserved domains on  [gi|1907199872|ref|XP_036011117|]
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cytosolic iron-sulfur assembly component 2A isoform X1 [Mus musculus]

Protein Classification

iron-sulfur cluster assembly protein( domain architecture ID 1838)

iron-sulfur cluster assembly protein such as MIP18 family proteins, which are involved in the assembly of iron-sulfur (Fe-S) clusters essential for the function of many proteins, including enzymes that catalyze metabolic reactions.

Gene Ontology:  GO:0016226|GO:0106035

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5133 super family cl00941
Uncharacterized conserved protein [Function unknown];
81-142 1.06e-19

Uncharacterized conserved protein [Function unknown];


The actual alignment was detected with superfamily member COG5133:

Pssm-ID: 470001  Cd Length: 181  Bit Score: 80.43  E-value: 1.06e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199872  81 IIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCV 142
Cdd:COG5133   116 LIGLCIRVRLERHLPPRFHVQVHIKKGTHISERQVNKQLNDKERVAAACENEQLLDVMEKML 177
 
Name Accession Description Interval E-value
COG5133 COG5133
Uncharacterized conserved protein [Function unknown];
81-142 1.06e-19

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227462  Cd Length: 181  Bit Score: 80.43  E-value: 1.06e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199872  81 IIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCV 142
Cdd:COG5133   116 LIGLCIRVRLERHLPPRFHVQVHIKKGTHISERQVNKQLNDKERVAAACENEQLLDVMEKML 177
 
Name Accession Description Interval E-value
COG5133 COG5133
Uncharacterized conserved protein [Function unknown];
81-142 1.06e-19

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227462  Cd Length: 181  Bit Score: 80.43  E-value: 1.06e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199872  81 IIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCV 142
Cdd:COG5133   116 LIGLCIRVRLERHLPPRFHVQVHIKKGTHISERQVNKQLNDKERVAAACENEQLLDVMEKML 177
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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