|
Name |
Accession |
Description |
Interval |
E-value |
| VacB |
COG0557 |
Exoribonuclease R [Transcription]; |
33-602 |
2.28e-111 |
|
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain] Cd Length: 711 Bit Score: 354.03 E-value: 2.28e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 33 PTGRVVGILQKNWRDYVVTFpskeeVQSQGKNaqkiLVTPWDYRIPK-IRIS-TQQAEALQDFRVVVRIDSWEATSVYPN 110
Cdd:COG0557 122 PEGRVVEILERANTRVVGRF-----EKEKGFG----FVVPDDKRLLQdIFIPpDDLNGAKDGDLVVVEITRYPERRGPPE 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 111 GHFVRVLGRIGDLEGEIATILVENSISVVpFS-----EAQmcempvNTPEnpwKVSPKEEQERKDLRTTHLVfSIDPKGC 185
Cdd:COG0557 193 GRVVEVLGSPGDPGAEILIAIRKHGLPHE-FPeevlaEAE------ALPD---EVPEADLKGRRDLRDLPLV-TIDGEDA 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 186 EDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVM 265
Cdd:COG0557 262 KDFDDAVSAEKLDNGGWRLGVHIADVSHYVRPGSALDREARKRGTSVYLPDRVIPMLPERLSNGLCSLNPGEDRLAMSCE 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 266 WELDKTSyEIKKVWYGRTIIRSAYKLFYEAAQELLDGNfsivddipelkaldKQSQQAKLEELVWAIGKLTDIARHIRAK 345
Cdd:COG0557 342 MEIDAKG-EVVSYEFYRSVIRSDARLTYEEVQAILDGK--------------DEELREEYADLVPMLEELYELAKILRKA 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 346 RDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKI-WESFPhqALLRQHPPPHQEFFSELR 424
Cdd:COG0557 407 REKRGAIDFDLPETKIILDEEGKPEDIVPRERNDAHKLIEEFMLLANEAVAEFLeKLKLP--FLYRVHEEPDPEKLEALR 484
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 425 ECAKAKGFFI---DTRSNKTLADSLDSAND-PKDPLVNK-LLRSMAtQAMsnalYfstgscAEEEFHHYGLALDKYTHFT 499
Cdd:COG0557 485 EFLANLGLKLkggDEPTPKDLQKLLEQVKGrPEEELLNTlLLRSMK-QAV----Y------SPENIGHFGLALEAYTHFT 553
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 500 SPIRRYSDIVVHRLLMAAISKDKKMEIKENLfsNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETeerciA 579
Cdd:COG0557 554 SPIRRYPDLLVHRALKAYLEGKRSPGLQEYL--EEELEEIAEHCSETERRADEAERDVVDLKKAEYMKDRVGEE-----F 626
|
570 580
....*....|....*....|...
gi 1907196286 580 DGVIYSIRTNGVLVFIPRFGIKG 602
Cdd:COG0557 627 EGVISGVTSFGLFVELDELGVEG 649
|
|
| RNB |
pfam00773 |
RNB domain; This domain is the catalytic domain of ribonuclease II. |
168-518 |
1.83e-106 |
|
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain] Cd Length: 314 Bit Score: 327.70 E-value: 1.83e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 168 RKDLRTThLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILS 247
Cdd:pfam00773 1 RKDLRDL-PFITIDPADAKDLDDAISVEKLPNGGYRLGVHIADVSHYVPPGSPLDREARKRGTSVYLPDRVIPMLPEKLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 248 ADLCSLLGGVDRYAVSVMWELDKTsYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDkqsqqaklee 327
Cdd:pfam00773 80 NDLCSLNPGEDRLALSVEITIDAD-GEVTSYEIYPSVIRSKARLTYEEVDDLLEGKDAEKDKPDLAEDLR---------- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 328 lvwaigKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIrDLIPKQPLEVHETVAECMILANHWVAKKIwESFPHQA 407
Cdd:pfam00773 149 ------LLYELAKILRAKRLQRGALDLDTPENKLILDEEGVI-DILIQERTDAHSLIEEFMLLANEAVARHL-QELGIPA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 408 LLRQHPPPHQEFFSELRECAKAKgffidtRSNKTLADSLDSANDPKDplvnkLLRSMATQAMSNALYFStgscaeEEFHH 487
Cdd:pfam00773 221 LYRVHPEPDLEKLNSLIKLLQLL------PDDKGLSKSLEKIKDDER-----LLSILLLRTMPRAEYSP------EPLGH 283
|
330 340 350
....*....|....*....|....*....|.
gi 1907196286 488 YGLALDKYTHFTSPIRRYSDIVVHRLLMAAI 518
Cdd:pfam00773 284 FGLGLDIYTHFTSPIRRYPDLIVHRQLKALL 314
|
|
| RNB |
smart00955 |
This domain is the catalytic domain of ribonuclease II; |
168-520 |
6.50e-100 |
|
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain] Cd Length: 286 Bit Score: 309.58 E-value: 6.50e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 168 RKDLRTTHLvFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILS 247
Cdd:smart00955 1 RVDLRDLPL-FTIDPEDAKDIDDAVSVEKLDNGGYRLGVHIADVSHYVKPGSALDREARKRGTSVYLPDRVIPMLPEELS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 248 ADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDgnfsivddipelkaldkqsqqaklee 327
Cdd:smart00955 80 NGLCSLNPGEDRLALSVEMTLDADGGEILDYEFYRSVIRSKARLTYEEVDAILE-------------------------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 328 lvwaigkltdiarhirakrdrcgalelegvevRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPhQA 407
Cdd:smart00955 134 --------------------------------KIVLDEEGKIEDIVPRERNDAHSLVEEFMILANEAVARFLAKNGI-PG 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 408 LLRQHPPPHQEFFSE-LRECAKAKGFFI-DTRSNKTLADSLDSANDPKDplvNKLLRSMATQAMSNALYFSTGScaeeef 485
Cdd:smart00955 181 LYRVHEGPDPEKLAElLKEFLALLGLLLlGGDGPKALAKLLEKIRDSPE---ERLLELLLLRSMPHAEYSVDNS------ 251
|
330 340 350
....*....|....*....|....*....|....*
gi 1907196286 486 HHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISK 520
Cdd:smart00955 252 GHFGLALDAYTHFTSPIRRYPDLIVHRQLKAALRG 286
|
|
| RNase_R |
TIGR02063 |
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ... |
35-602 |
1.34e-94 |
|
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain] Cd Length: 709 Bit Score: 309.59 E-value: 1.34e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 35 GRVVGILQKNWRDYVVTFpsKEEvqsqgkNAQKILVtPWDYRIP-KIRIS-TQQAEALQDFRVVVRIDSWEATSVYPNGH 112
Cdd:TIGR02063 125 ARVIKILERANDQIVGTF--YIE------NGIGFVI-PDDKRIYlDIFIPpEQILGAEEGDKVLVEITKYPDRNRPAIGK 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 113 FVRVLGRIGDLEGEIATILVENSISVVpFSEAQMCEmpvnTPENPWKVSPKEEQERKDLRttHLVF-SIDPKGCEDVDDT 191
Cdd:TIGR02063 196 VVEILGHADDPGIDILIIIRKHGIPYE-FPEEVLDE----AAKIPEEVPEEEIKGRKDLR--DLPFvTIDGEDAKDFDDA 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 192 LSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKT 271
Cdd:TIGR02063 269 VYVEKLKDGNYKLGVAIADVSHYVREGSALDKEALKRGTSVYLPDRVIPMLPERLSNGICSLNPNEDRLTLSCEMEIDKK 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 272 SYEIKKVWYgRTIIRSAYKLFYEAAQELLDGNfsivddipelKALDKqsQQAKLEELVWAigkLTDIARHIRAKRDRCGA 351
Cdd:TIGR02063 349 GRVKKYEFY-EAVINSHARLTYNQVNDIIEGK----------DALDK--KEPPLKEMLKN---LFELYKILRKKRKKRGA 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 352 LELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIwESFPHQALLRQHPPPHQE----FFSELRECA 427
Cdd:TIGR02063 413 IDFDSKEAKIILDENGKPIDIVPRERGDAHKLIEEFMIAANETVAEHL-EKAKLPFIYRVHERPSEEklqnLREFLKTLG 491
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 428 -KAKGFFIDTRSNKTLADSLDS-ANDPKDPLVNK-LLRSMAtQAMsnalyFSTgscaeEEFHHYGLALDKYTHFTSPIRR 504
Cdd:TIGR02063 492 iTLKGGTSDKPQPKDFQKLLEKvKGRPEEELINTvLLRSMQ-QAK-----YSP-----ENIGHFGLALEYYTHFTSPIRR 560
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 505 YSDIVVHRLLMAAISKDKK-MEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETEErciadGVI 583
Cdd:TIGR02063 561 YPDLIVHRLIKKALFGGENtTTEKEREYLEAKLEEIAEHSSKTERRADEAERDVNDWKKAEYMSEKIGEEFE-----GVI 635
|
570
....*....|....*....
gi 1907196286 584 YSIRTNGVLVFIPRFGIKG 602
Cdd:TIGR02063 636 SGVTSFGLFVELENNTIEG 654
|
|
| PRK11642 |
PRK11642 |
ribonuclease R; |
125-522 |
2.55e-33 |
|
ribonuclease R;
Pssm-ID: 236944 [Multi-domain] Cd Length: 813 Bit Score: 137.57 E-value: 2.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 125 GEIATILVEN---SISVvpfseaqmcEMPVNTPENPWKVSPKEEQE---------------RKDLRTTHLVfSIDPKGCE 186
Cdd:PRK11642 208 GKIVEVLGDNmgtGMAV---------DIALRTHEIPYIWPQAVEQQvaglkeevpeeakagRVDLRDLPLV-TIDGEDAR 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 187 DVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDR------Y 260
Cdd:PRK11642 278 DFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVVPMLPEVLSNGLCSLNPQVDRlcmvceM 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 261 AVSVMWELdkTSYEikkvwYGRTIIRSAYKLFYEAAQELLDGNfsivddiPELKAlDKQSQQAKLEELvWAIGKLTDIAR 340
Cdd:PRK11642 358 TISSKGRL--TGYK-----FYEAVMSSHARLTYTKVWHILQGD-------QDLRE-QYAPLVKHLEEL-HNLYKVLDKAR 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 341 HIRakrdrcGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIwESFPHQALLRQHPPPHQEFF 420
Cdd:PRK11642 422 EER------GGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFV-EKAKEPALFRIHDKPSTEAI 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 421 SELRECAKAKGFFI---DTRSNKTLADSLDSANDPKDplvNKLLRSMATQAMSNALYfstgscAEEEFHHYGLALDKYTH 497
Cdd:PRK11642 495 TSFRSVLAELGLELpggNKPEPRDYAELLESVADRPD---AEMLQTMLLRSMKQAIY------DPENRGHFGLALQSYAH 565
|
410 420
....*....|....*....|....*
gi 1907196286 498 FTSPIRRYSDIVVHRLLMAAISKDK 522
Cdd:PRK11642 566 FTSPIRRYPDLSLHRAIKYLLAKEQ 590
|
|
| Rrp44_S1 |
pfam17215 |
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ... |
578-661 |
2.82e-09 |
|
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
Pssm-ID: 435792 Cd Length: 87 Bit Score: 54.46 E-value: 2.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 578 IADGVIYSIRTNGVLVFIPRFGIKGAAYLKNKdslvisCGPEGSSEWKPG--SLQrsqnkiISTTAGGQSVTFHLFDHVT 655
Cdd:pfam17215 2 EEEGYVIKVFNNGIVVFVPKFGIEGLIRLEDL------TGDEPEAEFDADeySLT------FPDKGSGKKRTVGVFDKVR 69
|
....*.
gi 1907196286 656 VRISVQ 661
Cdd:pfam17215 70 VRVKSV 75
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| VacB |
COG0557 |
Exoribonuclease R [Transcription]; |
33-602 |
2.28e-111 |
|
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain] Cd Length: 711 Bit Score: 354.03 E-value: 2.28e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 33 PTGRVVGILQKNWRDYVVTFpskeeVQSQGKNaqkiLVTPWDYRIPK-IRIS-TQQAEALQDFRVVVRIDSWEATSVYPN 110
Cdd:COG0557 122 PEGRVVEILERANTRVVGRF-----EKEKGFG----FVVPDDKRLLQdIFIPpDDLNGAKDGDLVVVEITRYPERRGPPE 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 111 GHFVRVLGRIGDLEGEIATILVENSISVVpFS-----EAQmcempvNTPEnpwKVSPKEEQERKDLRTTHLVfSIDPKGC 185
Cdd:COG0557 193 GRVVEVLGSPGDPGAEILIAIRKHGLPHE-FPeevlaEAE------ALPD---EVPEADLKGRRDLRDLPLV-TIDGEDA 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 186 EDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVM 265
Cdd:COG0557 262 KDFDDAVSAEKLDNGGWRLGVHIADVSHYVRPGSALDREARKRGTSVYLPDRVIPMLPERLSNGLCSLNPGEDRLAMSCE 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 266 WELDKTSyEIKKVWYGRTIIRSAYKLFYEAAQELLDGNfsivddipelkaldKQSQQAKLEELVWAIGKLTDIARHIRAK 345
Cdd:COG0557 342 MEIDAKG-EVVSYEFYRSVIRSDARLTYEEVQAILDGK--------------DEELREEYADLVPMLEELYELAKILRKA 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 346 RDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKI-WESFPhqALLRQHPPPHQEFFSELR 424
Cdd:COG0557 407 REKRGAIDFDLPETKIILDEEGKPEDIVPRERNDAHKLIEEFMLLANEAVAEFLeKLKLP--FLYRVHEEPDPEKLEALR 484
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 425 ECAKAKGFFI---DTRSNKTLADSLDSAND-PKDPLVNK-LLRSMAtQAMsnalYfstgscAEEEFHHYGLALDKYTHFT 499
Cdd:COG0557 485 EFLANLGLKLkggDEPTPKDLQKLLEQVKGrPEEELLNTlLLRSMK-QAV----Y------SPENIGHFGLALEAYTHFT 553
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 500 SPIRRYSDIVVHRLLMAAISKDKKMEIKENLfsNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETeerciA 579
Cdd:COG0557 554 SPIRRYPDLLVHRALKAYLEGKRSPGLQEYL--EEELEEIAEHCSETERRADEAERDVVDLKKAEYMKDRVGEE-----F 626
|
570 580
....*....|....*....|...
gi 1907196286 580 DGVIYSIRTNGVLVFIPRFGIKG 602
Cdd:COG0557 627 EGVISGVTSFGLFVELDELGVEG 649
|
|
| RNB |
pfam00773 |
RNB domain; This domain is the catalytic domain of ribonuclease II. |
168-518 |
1.83e-106 |
|
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain] Cd Length: 314 Bit Score: 327.70 E-value: 1.83e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 168 RKDLRTThLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILS 247
Cdd:pfam00773 1 RKDLRDL-PFITIDPADAKDLDDAISVEKLPNGGYRLGVHIADVSHYVPPGSPLDREARKRGTSVYLPDRVIPMLPEKLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 248 ADLCSLLGGVDRYAVSVMWELDKTsYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDkqsqqaklee 327
Cdd:pfam00773 80 NDLCSLNPGEDRLALSVEITIDAD-GEVTSYEIYPSVIRSKARLTYEEVDDLLEGKDAEKDKPDLAEDLR---------- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 328 lvwaigKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIrDLIPKQPLEVHETVAECMILANHWVAKKIwESFPHQA 407
Cdd:pfam00773 149 ------LLYELAKILRAKRLQRGALDLDTPENKLILDEEGVI-DILIQERTDAHSLIEEFMLLANEAVARHL-QELGIPA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 408 LLRQHPPPHQEFFSELRECAKAKgffidtRSNKTLADSLDSANDPKDplvnkLLRSMATQAMSNALYFStgscaeEEFHH 487
Cdd:pfam00773 221 LYRVHPEPDLEKLNSLIKLLQLL------PDDKGLSKSLEKIKDDER-----LLSILLLRTMPRAEYSP------EPLGH 283
|
330 340 350
....*....|....*....|....*....|.
gi 1907196286 488 YGLALDKYTHFTSPIRRYSDIVVHRLLMAAI 518
Cdd:pfam00773 284 FGLGLDIYTHFTSPIRRYPDLIVHRQLKALL 314
|
|
| RNB |
smart00955 |
This domain is the catalytic domain of ribonuclease II; |
168-520 |
6.50e-100 |
|
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain] Cd Length: 286 Bit Score: 309.58 E-value: 6.50e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 168 RKDLRTTHLvFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILS 247
Cdd:smart00955 1 RVDLRDLPL-FTIDPEDAKDIDDAVSVEKLDNGGYRLGVHIADVSHYVKPGSALDREARKRGTSVYLPDRVIPMLPEELS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 248 ADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDgnfsivddipelkaldkqsqqaklee 327
Cdd:smart00955 80 NGLCSLNPGEDRLALSVEMTLDADGGEILDYEFYRSVIRSKARLTYEEVDAILE-------------------------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 328 lvwaigkltdiarhirakrdrcgalelegvevRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPhQA 407
Cdd:smart00955 134 --------------------------------KIVLDEEGKIEDIVPRERNDAHSLVEEFMILANEAVARFLAKNGI-PG 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 408 LLRQHPPPHQEFFSE-LRECAKAKGFFI-DTRSNKTLADSLDSANDPKDplvNKLLRSMATQAMSNALYFSTGScaeeef 485
Cdd:smart00955 181 LYRVHEGPDPEKLAElLKEFLALLGLLLlGGDGPKALAKLLEKIRDSPE---ERLLELLLLRSMPHAEYSVDNS------ 251
|
330 340 350
....*....|....*....|....*....|....*
gi 1907196286 486 HHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISK 520
Cdd:smart00955 252 GHFGLALDAYTHFTSPIRRYPDLIVHRQLKAALRG 286
|
|
| RNase_R |
TIGR02063 |
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ... |
35-602 |
1.34e-94 |
|
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain] Cd Length: 709 Bit Score: 309.59 E-value: 1.34e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 35 GRVVGILQKNWRDYVVTFpsKEEvqsqgkNAQKILVtPWDYRIP-KIRIS-TQQAEALQDFRVVVRIDSWEATSVYPNGH 112
Cdd:TIGR02063 125 ARVIKILERANDQIVGTF--YIE------NGIGFVI-PDDKRIYlDIFIPpEQILGAEEGDKVLVEITKYPDRNRPAIGK 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 113 FVRVLGRIGDLEGEIATILVENSISVVpFSEAQMCEmpvnTPENPWKVSPKEEQERKDLRttHLVF-SIDPKGCEDVDDT 191
Cdd:TIGR02063 196 VVEILGHADDPGIDILIIIRKHGIPYE-FPEEVLDE----AAKIPEEVPEEEIKGRKDLR--DLPFvTIDGEDAKDFDDA 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 192 LSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKT 271
Cdd:TIGR02063 269 VYVEKLKDGNYKLGVAIADVSHYVREGSALDKEALKRGTSVYLPDRVIPMLPERLSNGICSLNPNEDRLTLSCEMEIDKK 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 272 SYEIKKVWYgRTIIRSAYKLFYEAAQELLDGNfsivddipelKALDKqsQQAKLEELVWAigkLTDIARHIRAKRDRCGA 351
Cdd:TIGR02063 349 GRVKKYEFY-EAVINSHARLTYNQVNDIIEGK----------DALDK--KEPPLKEMLKN---LFELYKILRKKRKKRGA 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 352 LELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIwESFPHQALLRQHPPPHQE----FFSELRECA 427
Cdd:TIGR02063 413 IDFDSKEAKIILDENGKPIDIVPRERGDAHKLIEEFMIAANETVAEHL-EKAKLPFIYRVHERPSEEklqnLREFLKTLG 491
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 428 -KAKGFFIDTRSNKTLADSLDS-ANDPKDPLVNK-LLRSMAtQAMsnalyFSTgscaeEEFHHYGLALDKYTHFTSPIRR 504
Cdd:TIGR02063 492 iTLKGGTSDKPQPKDFQKLLEKvKGRPEEELINTvLLRSMQ-QAK-----YSP-----ENIGHFGLALEYYTHFTSPIRR 560
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 505 YSDIVVHRLLMAAISKDKK-MEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETEErciadGVI 583
Cdd:TIGR02063 561 YPDLIVHRLIKKALFGGENtTTEKEREYLEAKLEEIAEHSSKTERRADEAERDVNDWKKAEYMSEKIGEEFE-----GVI 635
|
570
....*....|....*....
gi 1907196286 584 YSIRTNGVLVFIPRFGIKG 602
Cdd:TIGR02063 636 SGVTSFGLFVELENNTIEG 654
|
|
| 3_prime_RNase |
TIGR00358 |
VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of ... |
35-602 |
7.98e-63 |
|
VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of paralogous 3-prime exoribonucleases in E. coli, plus the set of proteins apparently orthologous to one or the other in other eubacteria. VacB was characterized originally as required for the expression of virulence genes, but is now recognized as the exoribonuclease RNase R (Rnr). Its paralog in E. coli and H. influenzae is designated exoribonuclease II (Rnb). Both are involved in the degradation of mRNA, and consequently have strong pleiotropic effects that may be difficult to disentangle. Both these proteins share domain-level similarity (RNB, S1) with a considerable number of other proteins, and full-length similarity scoring below the trusted cutoff to proteins associated with various phenotypes but uncertain biochemistry; it may be that these latter proteins are also 3-prime exoribonucleases. [Transcription, Degradation of RNA]
Pssm-ID: 273033 [Multi-domain] Cd Length: 654 Bit Score: 222.28 E-value: 7.98e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 35 GRVVGILQKNWRDYVVTFPSKeevqsqgKNAQKILV-TPWDYRIPKIRISTQQAEALQDFRVVVRIDSWEATSVYPNGHF 113
Cdd:TIGR00358 72 AEVERILEPALTRFVGKFLGE-------NDFGFVVPdDPRIYLDIIVPKASVKNELAEGDKVVVELTEYPLRRNLFYGEI 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 114 VRVLGRIGDLEGEIATILVENSISVVPFS--EAQMCEMPVNTPENPWKVspkeeqeRKDLRTTHLVfSIDPKGCEDVDDT 191
Cdd:TIGR00358 145 TQILGNNDDPLIPWWVTLARHEIPFEFPDgvEQQAAKLQFDVDEQAKKY-------REDLTDLAFV-TIDGADAKDLDDA 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 192 LSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKT 271
Cdd:TIGR00358 217 VYVKKLPDGGWKLYVAIADVSYYVAENSPLDKEAKHRGFSVYLPGFVIPMLPEELSNGLCSLNPNEDRLVLVCEMTISAQ 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 272 SYEIKKVWYGRTIIRSAyKLFYeaaqelldgnfSIVDDIPElkalDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGA 351
Cdd:TIGR00358 297 GRITDNEFYPATIESKA-RLTY-----------DKVNDWLE----NDDELQPEYETLVEQLKALHQLSQALGEWRHKRGL 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 352 LELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHqALLRQHPPPHQEFFSELRECAKAKG 431
Cdd:TIGR00358 361 IDFEHPETKFIVDEEGRVIDIVAEVRRIAEKIIEEAMIVANICAARFLHNHKVP-GIYRVHPGPSKKKLQSLLEFLAELG 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 432 -----FFIDTRSNKTLADSLDSANDPKDP--LVNKLLRSmatqaMSNALYFStgscaeEEFHHYGLALDKYTHFTSPIRR 504
Cdd:TIGR00358 440 ltlpgGNAENVTTLDGACWLREVKDRPEYeiLVTRLLRS-----LSQAEYSP------EPLGHFGLGLEHYAHFTSPIRR 508
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 505 YSDIVVHRLLMAAISKDKKMEikENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETeerciADGVIY 584
Cdd:TIGR00358 509 YPDLTNHRLIKAVLAKEQTDT--ERYQPQDELLQIAEHCSDTERRARDAERDVADWLKCRYLLDKVGTE-----FSGEIS 581
|
570
....*....|....*...
gi 1907196286 585 SIRTNGVLVFIPRFGIKG 602
Cdd:TIGR00358 582 SVTRFGMFVRLDDNGIDG 599
|
|
| Rnb |
COG4776 |
Exoribonuclease II [Transcription]; |
154-659 |
8.64e-37 |
|
Exoribonuclease II [Transcription];
Pssm-ID: 443808 [Multi-domain] Cd Length: 644 Bit Score: 146.92 E-value: 8.64e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 154 PENPWKVsPKEEQERKDLrtTHLVF-SIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTY 232
Cdd:COG4776 177 GDDEWEL-LDEGLEREDL--TALPFvTIDSESTEDMDDALYIEKLENGGWKLTVAIADPTAYIPEGSELDKEARQRAFTN 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 233 YLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKT-----SYEIKKVWygrtiIRSAYKLFYEAAQELLDGNFSIV 307
Cdd:COG4776 254 YLPGFNIPMLPRELSDDLCSLKENEKRPALVCRVTIDADgsigdDIEFFAAW-----IRSKAKLAYDNVSDWLEGKGEWQ 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 308 DDIPELKaldkqsQQAKLeelvwaigkLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAEC 387
Cdd:COG4776 329 PENEEIA------EQIRL---------LHQFALARSQWRQQHALVFKDRPDYRFELDEKGNVLDIHAEPRRIANRIVEEA 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 388 MILANHWVAKkiwesfphqaLLRQHP-----PPHQEFFSELRECAKA-----------------KGF-----FIDTRSNK 440
Cdd:COG4776 394 MIAANICAAR----------VLREHLgfgifNVHSGFDPEKLEQAVEllaehgiefdpeqlltlEGFcalrrELDAQPTS 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 441 TLaDSldsandpkdplvnkLLRSMAT-QAMSNalyfstgscaeEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAIS 519
Cdd:COG4776 464 YL-DS--------------RLRRFQTfAEIST-----------EPGPHFGLGLDAYATWTSPIRKYGDMVNHRLIKAVIL 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 520 KDKkmeikenlfSNKNLEELCRHINNR---NRAAQRSQKqsTELFqCMYFKDRdAETEERCIADgvIYSIR--------- 587
Cdd:COG4776 518 GQP---------AEKPDEELTERLAERrrlNRMAERDVA--DWLY-ARYLKPK-VGSGQVFTAE--IIDINrgglrvrll 582
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907196286 588 TNGVLVFIPrfgikgAAYL-KNKDSLVIScgpegsseWKPGSLQrsqnkiistTAGGqsVTFHLFDHVTVRIS 659
Cdd:COG4776 583 ENGAVAFIP------ASFIhSVRDELVCS--------QEEGTVY---------IKGE--VRYKLGDTIQVTLA 630
|
|
| PRK11642 |
PRK11642 |
ribonuclease R; |
125-522 |
2.55e-33 |
|
ribonuclease R;
Pssm-ID: 236944 [Multi-domain] Cd Length: 813 Bit Score: 137.57 E-value: 2.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 125 GEIATILVEN---SISVvpfseaqmcEMPVNTPENPWKVSPKEEQE---------------RKDLRTTHLVfSIDPKGCE 186
Cdd:PRK11642 208 GKIVEVLGDNmgtGMAV---------DIALRTHEIPYIWPQAVEQQvaglkeevpeeakagRVDLRDLPLV-TIDGEDAR 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 187 DVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDR------Y 260
Cdd:PRK11642 278 DFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVVPMLPEVLSNGLCSLNPQVDRlcmvceM 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 261 AVSVMWELdkTSYEikkvwYGRTIIRSAYKLFYEAAQELLDGNfsivddiPELKAlDKQSQQAKLEELvWAIGKLTDIAR 340
Cdd:PRK11642 358 TISSKGRL--TGYK-----FYEAVMSSHARLTYTKVWHILQGD-------QDLRE-QYAPLVKHLEEL-HNLYKVLDKAR 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 341 HIRakrdrcGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIwESFPHQALLRQHPPPHQEFF 420
Cdd:PRK11642 422 EER------GGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFV-EKAKEPALFRIHDKPSTEAI 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 421 SELRECAKAKGFFI---DTRSNKTLADSLDSANDPKDplvNKLLRSMATQAMSNALYfstgscAEEEFHHYGLALDKYTH 497
Cdd:PRK11642 495 TSFRSVLAELGLELpggNKPEPRDYAELLESVADRPD---AEMLQTMLLRSMKQAIY------DPENRGHFGLALQSYAH 565
|
410 420
....*....|....*....|....*
gi 1907196286 498 FTSPIRRYSDIVVHRLLMAAISKDK 522
Cdd:PRK11642 566 FTSPIRRYPDLSLHRAIKYLLAKEQ 590
|
|
| PRK05054 |
PRK05054 |
exoribonuclease II; Provisional |
164-615 |
2.12e-30 |
|
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain] Cd Length: 644 Bit Score: 127.30 E-value: 2.12e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 164 EEQERKDLrtTHLVF-SIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDML 242
Cdd:PRK05054 186 EGLEREDL--TALDFvTIDSASTEDMDDALYVEKLPDGGLQLTVAIADPTAYIAEGSKLDKAARQRAFTNYLPGFNIPML 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 243 PSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAaqelldgnfsiVDDIPElKALDKQSQQ 322
Cdd:PRK05054 264 PRELSDDLCSLRPNERRPALACRVTIDADGTIEDDIRFFAAWIESKAKLAYDN-----------VSDWLE-NGGDWQPES 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 323 AKLEELVWAIGKLTDIARHIRAK-----RDRcgalelegVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAK 397
Cdd:PRK05054 332 EAIAEQIRLLHQFCLARSEWRKQhalvfKDR--------PDYRFELGEKGEVLDIVAEPRRIANRIVEESMIAANICAAR 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 398 kiwesfphqaLLRQHPP-----PHQEFFSELRECA----KAKGFFIDTRSNKTLA---------DSLdsandPKDPLVNK 459
Cdd:PRK05054 404 ----------VLRDKLGfgiynVHSGFDPANAEQAvallKEHGLHFDAEELLTLEgfcklrrelDAQ-----PTGYLDSR 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 460 LLRSMATQAMSNalyfstgscaeEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLfsnknLEEL 539
Cdd:PRK05054 469 IRRFQSFAEIST-----------EPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETAERPQDEI-----TVQL 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 540 CRHiNNRNRAAQRSQKqstELFQCMYFKDRdAETEERCIAD-------GVIYSIRTNGVLVFIPrfgikgAAYL-KNKDS 611
Cdd:PRK05054 533 AER-RRLNRMAERDVG---DWLYARYLKDK-AGTDTRFAAEiidisrgGMRVRLLENGAVAFIP------ASFLhAVRDE 601
|
....
gi 1907196286 612 LVIS 615
Cdd:PRK05054 602 LVCN 605
|
|
| OB_Dis3 |
pfam17849 |
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ... |
68-135 |
1.59e-24 |
|
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain] Cd Length: 77 Bit Score: 97.68 E-value: 1.59e-24
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907196286 68 ILVTPWDYRIPKIRISTQQA--------EALQDFRVVVRIDSWEATSVYPNGHFVRVLGRIGDLEGEIATILVENS 135
Cdd:pfam17849 2 VLFVPRDKRIPRIRIPTKSApeeflenpEDLEGKLFVVKIDDWPENSRYPLGHIVKVLGEIGDIETETEAILLENG 77
|
|
| Rrp44_S1 |
pfam17215 |
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases ... |
578-661 |
2.82e-09 |
|
S1 domain; This domain corresponds to the S1 domain found at the C-terminus of ribonucleases such as yeast Rrp44.
Pssm-ID: 435792 Cd Length: 87 Bit Score: 54.46 E-value: 2.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 578 IADGVIYSIRTNGVLVFIPRFGIKGAAYLKNKdslvisCGPEGSSEWKPG--SLQrsqnkiISTTAGGQSVTFHLFDHVT 655
Cdd:pfam17215 2 EEEGYVIKVFNNGIVVFVPKFGIEGLIRLEDL------TGDEPEAEFDADeySLT------FPDKGSGKKRTVGVFDKVR 69
|
....*.
gi 1907196286 656 VRISVQ 661
Cdd:pfam17215 70 VRVKSV 75
|
|
| muHD |
pfam10291 |
Muniscin C-terminal mu homology domain; The muniscins are a family of endocytic adaptors that ... |
83-201 |
5.84e-03 |
|
Muniscin C-terminal mu homology domain; The muniscins are a family of endocytic adaptors that is conserved from yeast to humans.This C-terminal domain is structurally similar to mu homology domains, and is the region of the muniscin proteins involved in the interactions with the endocytic adaptor-scaffold proteins Ede1-eps15. This interaction influences muniscin localization. The muniscins provide a combined adaptor-membrane-tubulation activity that is important for regulating endocytosis.
Pssm-ID: 463046 Cd Length: 255 Bit Score: 39.22 E-value: 5.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907196286 83 STQQAEALQDFRVVVRIDSWEATSV--YPNGHFV----RVLGRIGDLE----GEIATILVENSISVVPFSEAQMcempvn 152
Cdd:pfam10291 134 AIASAVVLENLQVVVNLDGSHATSAqsKPQGTFNkeksRITWKLPELSltsdGDGGKLIARFMTEGGASKPGGV------ 207
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1907196286 153 tpENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDtLSVRTLNNGN 201
Cdd:pfam10291 208 --AVKFEIETGDTLSGLGISLVDQVDEEDPFGGGWKLV-PTKRRLAAGK 253
|
|
| |
