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Conserved domains on  [gi|1839694162|ref|XP_034065625|]
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nucleolar and coiled-body phosphoprotein 1 isoform X13 [Gymnodraco acuticeps]

Protein Classification

nucleolar and coiled-body phosphoprotein 1 family protein( domain architecture ID 10523427)

nucleolar and coiled-body phosphoprotein 1 (NOLC1) family protein; similar to mammalian NOLC1 (also known as Nopp140) which may participate in the regulation of rRNA transcription by interacting with the largest subunit of RNA polymerase I, and to Saccharomyces cerevisiae suppressor protein Srp40 which is a weak suppressor of a mutant of the subunit AC40 of DNA dependent RNA polymerase I and III; may be a chaperone involved in nucleocytoplasmic transport

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SRP40_C pfam05022
SRP40, C-terminal domain; This presumed domain is found at the C-terminus of the S. cerevisiae ...
 1052-1125 7.08e-32

SRP40, C-terminal domain; This presumed domain is found at the C-terminus of the S. cerevisiae SRP40 protein and its homologs. SRP40/nopp40 is a chaperone involved in nucleocytoplasmic transport. SRP40 is also a suppressor of mutant AC40 subunit of RNA polymerase I and III.


:

Pssm-ID: 461525  Cd Length: 75  Bit Score: 118.79  E-value: 7.08e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839694162 1052 PFRRIREEEVAV--DPRLQDNSFDAKfGSNGDWGQKANDTLRFTKGKSFRHEKTKKKRGSYRGGAINSTSVNSIKF 1125
Cdd:pfam05022    1 PFQRVDPEDVVVfaDPRLADNSYEAK-GAEDDYGEKANEDLIVTRGKGFRKEKNKKKRGSYRGGAIDTNSVNSIKF 75
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
621-771 1.10e-08

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07994:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 647  Bit Score: 59.11  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  621 KPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPA 700
Cdd:PRK07994   360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1839694162  701 KAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKAKPATPAKAKPATPAKAKPATP 771
Cdd:PRK07994   440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP 510
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 601-1008 1.40e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  601 AKPAKPATPAK-----AKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSD 675
Cdd:PHA03247  2593 PQSARPRAPVDdrgdpRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  676 SSSEDEEPAKAKP-ATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATP-AKAKPA 753
Cdd:PHA03247  2673 AAQASSPPQRPRRrAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPaGPATPG 2752

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  754 TPAK-AKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPAAKPATPASKPATPTAKAAAAESSSESSSEDEEPA 832
Cdd:PHA03247  2753 GPARpARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  833 KAKPAisAKAKPTTPAAKPAAAAESSSDSDSDSEDEAAKPAVKKPTPAAEAPASTPKASKKKAESSSDSSDSETEAKTTP 912
Cdd:PHA03247  2833 SAQPT--APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQ 2910

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  913 AKPPVTNGKAATPKAATPKAATPKTPAKPAESSSSDSSSEEEEEASKSAVKPATPAATPKTTPAAKAKESSSSDSSSEEd 992
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAP- 2989

                          410
                   ....*....|....*.
gi 1839694162  993 aprraatAPTTPTTNG 1008
Cdd:PHA03247  2990 -------ASSTPPLTG 2998
 
Name Accession Description Interval E-value
SRP40_C pfam05022
SRP40, C-terminal domain; This presumed domain is found at the C-terminus of the S. cerevisiae ...
 1052-1125 7.08e-32

SRP40, C-terminal domain; This presumed domain is found at the C-terminus of the S. cerevisiae SRP40 protein and its homologs. SRP40/nopp40 is a chaperone involved in nucleocytoplasmic transport. SRP40 is also a suppressor of mutant AC40 subunit of RNA polymerase I and III.


Pssm-ID: 461525  Cd Length: 75  Bit Score: 118.79  E-value: 7.08e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839694162 1052 PFRRIREEEVAV--DPRLQDNSFDAKfGSNGDWGQKANDTLRFTKGKSFRHEKTKKKRGSYRGGAINSTSVNSIKF 1125
Cdd:pfam05022    1 PFQRVDPEDVVVfaDPRLADNSYEAK-GAEDDYGEKANEDLIVTRGKGFRKEKNKKKRGSYRGGAIDTNSVNSIKF 75
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 621-771 1.10e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 59.11  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  621 KPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPA 700
Cdd:PRK07994   360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1839694162  701 KAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKAKPATPAKAKPATPAKAKPATP 771
Cdd:PRK07994   440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP 510
PHA03247 PHA03247
large tegument protein UL36; Provisional
 601-1008 1.40e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  601 AKPAKPATPAK-----AKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSD 675
Cdd:PHA03247  2593 PQSARPRAPVDdrgdpRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  676 SSSEDEEPAKAKP-ATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATP-AKAKPA 753
Cdd:PHA03247  2673 AAQASSPPQRPRRrAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPaGPATPG 2752

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  754 TPAK-AKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPAAKPATPASKPATPTAKAAAAESSSESSSEDEEPA 832
Cdd:PHA03247  2753 GPARpARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  833 KAKPAisAKAKPTTPAAKPAAAAESSSDSDSDSEDEAAKPAVKKPTPAAEAPASTPKASKKKAESSSDSSDSETEAKTTP 912
Cdd:PHA03247  2833 SAQPT--APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQ 2910

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  913 AKPPVTNGKAATPKAATPKAATPKTPAKPAESSSSDSSSEEEEEASKSAVKPATPAATPKTTPAAKAKESSSSDSSSEEd 992
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAP- 2989

                          410
                   ....*....|....*.
gi 1839694162  993 aprraatAPTTPTTNG 1008
Cdd:PHA03247  2990 -------ASSTPPLTG 2998
 
Name Accession Description Interval E-value
SRP40_C pfam05022
SRP40, C-terminal domain; This presumed domain is found at the C-terminus of the S. cerevisiae ...
 1052-1125 7.08e-32

SRP40, C-terminal domain; This presumed domain is found at the C-terminus of the S. cerevisiae SRP40 protein and its homologs. SRP40/nopp40 is a chaperone involved in nucleocytoplasmic transport. SRP40 is also a suppressor of mutant AC40 subunit of RNA polymerase I and III.


Pssm-ID: 461525  Cd Length: 75  Bit Score: 118.79  E-value: 7.08e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1839694162 1052 PFRRIREEEVAV--DPRLQDNSFDAKfGSNGDWGQKANDTLRFTKGKSFRHEKTKKKRGSYRGGAINSTSVNSIKF 1125
Cdd:pfam05022    1 PFQRVDPEDVVVfaDPRLADNSYEAK-GAEDDYGEKANEDLIVTRGKGFRKEKNKKKRGSYRGGAIDTNSVNSIKF 75
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 621-771 1.10e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 59.11  E-value: 1.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  621 KPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPA 700
Cdd:PRK07994   360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1839694162  701 KAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKAKPATPAKAKPATPAKAKPATP 771
Cdd:PRK07994   440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP 510
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 683-775 2.45e-07

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 55.28  E-value: 2.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  683 PAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAEsssdsssedeePATPAKAKPATPAKAKPATPAKAKPAT 762
Cdd:PRK12270    38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAA-----------PAAPPKPAAAAAAAAAPAAPPAAAAAA 106

                           90
                   ....*....|...
gi 1839694162  763 PAKAKPATPVAKP 775
Cdd:PRK12270   107 APAAAAVEDEVTP 119
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 646-772 4.22e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 53.95  E-value: 4.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  646 PAKAKPATPAKAKPATPVAKPaaaaesssdssSEDEEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAES 725
Cdd:PRK14951   373 AAPAEKKTPARPEAAAPAAAP-----------VAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAA 441

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1839694162  726 SSDSSSEDEEPATPAKAKPATPAKAKPATPAKAKPATPAKAKPATPV 772
Cdd:PRK14951   442 PAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARL 488
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 601-716 7.17e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 53.56  E-value: 7.17e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  601 AKPAKPATPAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSED 680
Cdd:PRK14951   373 AAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPP 452

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1839694162  681 EEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPV 716
Cdd:PRK14951   453 AQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARL 488
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 684-775 9.59e-07

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 53.36  E-value: 9.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  684 AKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAaaesssdsssedeePATPAKAKPATPAKAKPATPAKAKPATP 763
Cdd:PRK12270    34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPA--------------PAPPAAAAPAAPPKPAAAAAAAAAPAAP 99

                           90
                   ....*....|..
gi 1839694162  764 AKAKPATPVAKP 775
Cdd:PRK12270   100 PAAAAAAAPAAA 111
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
601-771 3.32e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 51.42  E-value: 3.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  601 AKPAKPATPAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSED 680
Cdd:PRK12323   391 APAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPR 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  681 EEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKP----ATPAKAKPATPA 756
Cdd:PRK12323   471 PVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPddafETLAPAPAAAPA 550

                          170
                   ....*....|....*
gi 1839694162  757 KAKPATPAKAKPATP 771
Cdd:PRK12323   551 PRAAAATEPVVAPRP 565
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
604-775 7.15e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 50.26  E-value: 7.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  604 AKPATPAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEeP 683
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA-P 450

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  684 AKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKAKPAT-------PA 756
Cdd:PRK12323   451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWvaesipdPA 530

                          170
                   ....*....|....*....
gi 1839694162  757 KAKPATPAKAKPATPVAKP 775
Cdd:PRK12323   531 TADPDDAFETLAPAPAAAP 549
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 602-719 1.12e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 49.33  E-value: 1.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  602 KPAKPAT-PAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSED 680
Cdd:PRK14951   365 KPAAAAEaAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA 444

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1839694162  681 EEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKP 719
Cdd:PRK14951   445 VALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAP 483
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 647-774 3.36e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 48.35  E-value: 3.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  647 AKAKPATPAKAKPATPVAKPaaaaesssdsssedeePAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPaaaaess 726
Cdd:PRK12270    34 ADYGPGSTAAPTAAAAAAAA----------------AASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAA------- 90

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1839694162  727 sdsssedeEPATPAKAKPATPAKAKPATPAKAKPATPAKAkPATPVAK 774
Cdd:PRK12270    91 --------AAAAAPAAPPAAAAAAAPAAAAVEDEVTPLRG-AAAAVAK 129
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 646-719 8.51e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 46.81  E-value: 8.51e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1839694162  646 PAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKP 719
Cdd:PRK12270    38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAA 111
PHA03247 PHA03247
large tegument protein UL36; Provisional
 601-1008 1.40e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  601 AKPAKPATPAK-----AKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPAAAAESSSD 675
Cdd:PHA03247  2593 PQSARPRAPVDdrgdpRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  676 SSSEDEEPAKAKP-ATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATP-AKAKPA 753
Cdd:PHA03247  2673 AAQASSPPQRPRRrAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPaGPATPG 2752

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  754 TPAK-AKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPAAKPATPASKPATPTAKAAAAESSSESSSEDEEPA 832
Cdd:PHA03247  2753 GPARpARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  833 KAKPAisAKAKPTTPAAKPAAAAESSSDSDSDSEDEAAKPAVKKPTPAAEAPASTPKASKKKAESSSDSSDSETEAKTTP 912
Cdd:PHA03247  2833 SAQPT--APPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQ 2910

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  913 AKPPVTNGKAATPKAATPKAATPKTPAKPAESSSSDSSSEEEEEASKSAVKPATPAATPKTTPAAKAKESSSSDSSSEEd 992
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAP- 2989

                          410
                   ....*....|....*.
gi 1839694162  993 aprraatAPTTPTTNG 1008
Cdd:PHA03247  2990 -------ASSTPPLTG 2998
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 683-772 3.25e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 44.86  E-value: 3.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  683 PAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKAKPATPAKAKPAT 762
Cdd:PRK07994   366 PEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAA 445

                           90
                   ....*....|
gi 1839694162  763 PAKAKPATPV 772
Cdd:PRK07994   446 ASRARPVNSA 455
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 610-718 3.77e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 44.88  E-value: 3.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  610 AKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPVAKPaaaaesssdsssedeePAKAKPA 689
Cdd:PRK12270    34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAA----------------AAAAAPA 97

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1839694162  690 TPAKAKPATPAKAKPSTPAKAK---PATPVAK 718
Cdd:PRK12270    98 APPAAAAAAAPAAAAVEDEVTPlrgAAAAVAK 129
PHA03247 PHA03247
large tegument protein UL36; Provisional
 646-971 6.03e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 6.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  646 PAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPA--KAKPATPAKAKPSTPAKAKPATPVAKPAAAA 723
Cdd:PHA03247  2556 PPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA 2635

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  724 ESSSDSSSEDEEPATPAKAKPATPAKAKP---ATPAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPAAK 800
Cdd:PHA03247  2636 NEPDPHPPPTVPPPERPRDDPAPGRVSRPrraRRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHAL 2715

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  801 PATPASKPATPTAKAAAAESSSESSSEDEEPAKAKPAiSAKAKPTTPAAKPAAAAESSSDSDSDSEDEAAKPAVKKPTPA 880
Cdd:PHA03247  2716 VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPG-GPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSES 2794

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  881 AEAPASTPKASKKKAESSSDSSDSETEAKTTPAKPPVTngkAATPKAATPKAATPKTPAKPAESSSSDSSSEEEEEASKS 960
Cdd:PHA03247  2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT---SAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSP 2871

                          330
                   ....*....|.
gi 1839694162  961 AVKPATPAATP 971
Cdd:PHA03247  2872 AAKPAAPARPP 2882
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 646-719 9.73e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 43.34  E-value: 9.73e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1839694162  646 PAKAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAkakPATPAKAKPSTPAKAKPATPVAKP 719
Cdd:PRK12270    49 AAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAA---PAAPPAAAAAAAPAAAAVEDEVTP 119
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
582-775 1.26e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  582 PAAAAAESSSDSSSEDEEPAKPAKPATPAKAKSATPAKAK-PATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPA 660
Cdd:PRK07003   385 ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEaPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCD 464

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  661 TPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPAkakpstPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPA 740
Cdd:PRK07003   465 ERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATP------AAVPDARAPAAASREDAPAAAAPPAPEARPPTPA 538

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1839694162  741 KAKPATPA------------------------KAKPATPAKAKPATPAKAKPATPVAKP 775
Cdd:PRK07003   539 AAAPAARAggaaaaldvlrnagmrvssdrgarAAAAAKPAAAPAAAPKPAAPRVAVQVP 597
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 665-775 1.52e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  665 KPAAAAESSSDSSSEDEEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKP 744
Cdd:PRK14951   365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA 444

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1839694162  745 ATPAKAKPATPAKAKPATPAKAKPATPVAKP 775
Cdd:PRK14951   445 VALAPAPPAQAAPETVAIPVRVAPEPAVASA 475
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
601-773 2.43e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  601 AKPAKPATPAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPAKakPATPVAKPAAAAESSSDSSSED 680
Cdd:PRK07003   442 AADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAA--APSAATPAAVPDARAPAAASRE 519

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  681 EEPAKAKPATPAkAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKA---------K 751
Cdd:PRK07003   520 DAPAAAAPPAPE-ARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAaprvavqvpT 598

                          170       180
                   ....*....|....*....|..
gi 1839694162  752 PATPAKAKPATPAKAKPATPVA 773
Cdd:PRK07003   599 PRARAATGDAPPNGAARAEQAA 620
PHA03247 PHA03247
large tegument protein UL36; Provisional
 603-977 2.96e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  603 PAKPATPAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAkAKPATPAKAKPATPVAKPAAAAESSSDSSSEDEE 682
Cdd:PHA03247  2717 SATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPP-TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESR 2795

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  683 PAKAKPATPAKAKPATPAKAkPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATP--AKAKPATPAKAKPatpakakP 760
Cdd:PHA03247  2796 ESLPSPWDPADPPAAVLAPA-AALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlgGSVAPGGDVRRRP-------P 2867

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  761 ATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPAAKPATPASKPATPTAKAAAAESSSESSSEDEEPAKAKPAisA 840
Cdd:PHA03247  2868 SRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA--P 2945

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  841 KAKPTTPAAKPAAAAESSSDSDSDSEDEAAKPAVKKPTPAAEAPASTPKASKKKAESSSDSSDSETEAKTTPAKPPVTng 920
Cdd:PHA03247  2946 TTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPPVS-- 3023

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1839694162  921 kaatpkaatpkaaTPKTPAKPAESSSSDSSSEEEEEASKSAVKPATPAATPKTTPAA 977
Cdd:PHA03247  3024 -------------LKQTLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFA 3067
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 683-760 6.04e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 40.70  E-value: 6.04e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1839694162  683 PAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPATPAKAKPATPAKAKP 760
Cdd:PRK14954   382 PSPAGSPDVKKKAPEPDLPQPDRHPGPAKPEAPGARPAELPSPASAPTPEQQPPVARSAPLPPSPQASAPRNVASGKP 459
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 587-771 7.09e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 7.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  587 AESSSDSSSEDEEPAKPAKPATPAKAKSATPAKAKPATPVAKPAAAAESSSDSSSEDEEPAKAKPATPakakPATPVAKP 666
Cdd:PRK07764   614 RPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAP----PPAPAPAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1839694162  667 AAAAESSSDSSSEDEEPAKAKPATPAKAKPATPAKAKPSTPAKAKPATPVAKPAAAAESSSDSSSEDEEPATPAKAKPAT 746
Cdd:PRK07764   690 PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA 769

                          170       180
                   ....*....|....*....|....*
gi 1839694162  747 PAKAKPATPAKAKPATPAKAKPATP 771
Cdd:PRK07764   770 PAAAPPPSPPSEEEEMAEDDAPSMD 794
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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