|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
56-433 |
7.33e-113 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 349.39 E-value: 7.33e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 56 ASRRKRLTAHFEDLEQCYFSTRMSRIS----------DDSRTASQLDEFQECLSKFTRYNSVRPLATLSyASDLYNGSSI 125
Cdd:PLN00181 407 AAAEKPLARYYSALSENGRSSEKSSMSnpakppdfyiNDSRQGGWIDPFLEGLCKYLSFSKLRVKADLK-QGDLLNSSNL 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 126 VSSIEFDRDCDYFAIAGVTKKIKVYEYGTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTG 205
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIFECESIIKDGRDIHYPVVELASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARS 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 206 QRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYY 285
Cdd:PLN00181 566 QLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFPSESGRSLAFGSADHKVYYY 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 286 DLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYC------LRSFKGHINEKNFVGLASNGDYIAC 359
Cdd:PLN00181 646 DLRNPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSMSISginetpLHSFMGHTNVKNFVGLSVSDGYIAT 725
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720355455 360 GSENNSLYLYYKGLSKTLLTFKFDTVKSVldKDRKEDDTNEFVSAVCWRalsdGESNVLIAANSQGTIKVLELV 433
Cdd:PLN00181 726 GSETNEVFVYHKAFPMPVLSYKFKTIDPV--SGLEVDDASQFISSVCWR----GQSSTLVAANSTGNIKILEMV 793
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
123-429 |
1.57e-38 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 140.55 E-value: 1.57e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 123 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGTVIQDAVD-IHYpenemtcnSKISCISWSSYHKNLLASSdYEGTVILWD 201
Cdd:cd00200 9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLkGHT--------GPVRDVAASADGTYLASGS-SDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 202 GFTGQRSKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYhLAFGCADH 280
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFS-PDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDwVNSVAFSPDGTF-VASSSQDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 281 CVHYYDLRNTKqPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIAC 359
Cdd:cd00200 158 TIKLWDLRTGK-CVATLTGHTGEVNSVAFSpDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLAS 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 360 GSENNSLYLYYKGLSKTLLTFKfdtvksvldkdrkedDTNEFVSAVCWralsDGESNVLIAANSQGTIKV 429
Cdd:cd00200 237 GSEDGTIRVWDLRTGECVQTLS---------------GHTNSVTSLAW----SPDGKRLASGSADGTIRI 287
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
110-429 |
2.61e-35 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 134.65 E-value: 2.61e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 110 LATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY--GTVIQdAVDIHypenemtcNSKISCISWSSyHKNL 187
Cdd:COG2319 107 LATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLatGKLLR-TLTGH--------SGAVTSVAFSP-DGKL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 188 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFS 266
Cdd:COG2319 177 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGsVRSVAFS 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 267 PSSRYhLAFGCADHCVHYYDLrNTKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEK 345
Cdd:COG2319 256 PDGRL-LASGSADGTVRLWDL-ATGELLRTLTGHSGGVNSVAFSpDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAV 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 346 NFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKfdtvksvldkdrkedDTNEFVSAVCWRAlsDGesNVLIAANSQG 425
Cdd:COG2319 334 RSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLT---------------GHTGAVTSVAFSP--DG--RTLASGSADG 394
|
....
gi 1720355455 426 TIKV 429
Cdd:COG2319 395 TVRL 398
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
204-244 |
1.29e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 39.22 E-value: 1.29e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1720355455 204 TGQRSKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWS 244
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFS-PDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
205-244 |
7.87e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.94 E-value: 7.87e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1720355455 205 GQRSKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWS 244
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFS-PDGKLLASGSDDGTVKVWD 39
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
56-433 |
7.33e-113 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 349.39 E-value: 7.33e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 56 ASRRKRLTAHFEDLEQCYFSTRMSRIS----------DDSRTASQLDEFQECLSKFTRYNSVRPLATLSyASDLYNGSSI 125
Cdd:PLN00181 407 AAAEKPLARYYSALSENGRSSEKSSMSnpakppdfyiNDSRQGGWIDPFLEGLCKYLSFSKLRVKADLK-QGDLLNSSNL 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 126 VSSIEFDRDCDYFAIAGVTKKIKVYEYGTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTG 205
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIFECESIIKDGRDIHYPVVELASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARS 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 206 QRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYY 285
Cdd:PLN00181 566 QLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFPSESGRSLAFGSADHKVYYY 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 286 DLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYC------LRSFKGHINEKNFVGLASNGDYIAC 359
Cdd:PLN00181 646 DLRNPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSMSISginetpLHSFMGHTNVKNFVGLSVSDGYIAT 725
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720355455 360 GSENNSLYLYYKGLSKTLLTFKFDTVKSVldKDRKEDDTNEFVSAVCWRalsdGESNVLIAANSQGTIKVLELV 433
Cdd:PLN00181 726 GSETNEVFVYHKAFPMPVLSYKFKTIDPV--SGLEVDDASQFISSVCWR----GQSSTLVAANSTGNIKILEMV 793
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
123-429 |
1.57e-38 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 140.55 E-value: 1.57e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 123 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGTVIQDAVD-IHYpenemtcnSKISCISWSSYHKNLLASSdYEGTVILWD 201
Cdd:cd00200 9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLkGHT--------GPVRDVAASADGTYLASGS-SDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 202 GFTGQRSKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYhLAFGCADH 280
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFS-PDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDwVNSVAFSPDGTF-VASSSQDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 281 CVHYYDLRNTKqPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIAC 359
Cdd:cd00200 158 TIKLWDLRTGK-CVATLTGHTGEVNSVAFSpDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLAS 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 360 GSENNSLYLYYKGLSKTLLTFKfdtvksvldkdrkedDTNEFVSAVCWralsDGESNVLIAANSQGTIKV 429
Cdd:cd00200 237 GSEDGTIRVWDLRTGECVQTLS---------------GHTNSVTSLAW----SPDGKRLASGSADGTIRI 287
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
110-429 |
2.61e-35 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 134.65 E-value: 2.61e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 110 LATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY--GTVIQdAVDIHypenemtcNSKISCISWSSyHKNL 187
Cdd:COG2319 107 LATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLatGKLLR-TLTGH--------SGAVTSVAFSP-DGKL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 188 LASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFS 266
Cdd:COG2319 177 LASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGsVRSVAFS 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 267 PSSRYhLAFGCADHCVHYYDLrNTKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEK 345
Cdd:COG2319 256 PDGRL-LASGSADGTVRLWDL-ATGELLRTLTGHSGGVNSVAFSpDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAV 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 346 NFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKfdtvksvldkdrkedDTNEFVSAVCWRAlsDGesNVLIAANSQG 425
Cdd:COG2319 334 RSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLT---------------GHTGAVTSVAFSP--DG--RTLASGSADG 394
|
....
gi 1720355455 426 TIKV 429
Cdd:COG2319 395 TVRL 398
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
108-369 |
1.52e-32 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 127.33 E-value: 1.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 108 RPLATLSyasdlyNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY--GTVIQdAVDIHypenemtcNSKISCISWSSyHK 185
Cdd:COG2319 153 KLLRTLT------GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLatGKLLR-TLTGH--------TGAVRSVAFSP-DG 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 186 NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVK 264
Cdd:COG2319 217 KLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSP-DGRLLASGSADGTVRLWDLATGELLRTLTGHSGgVNSVA 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 265 FSPSSRYhLAFGCADHCVHYYDLrNTKQPIMVFKGHRKAVSYAKFVS-GEEIVSASTDSQLKLWNVGKPYCLRSFKGHIN 343
Cdd:COG2319 296 FSPDGKL-LASGSDDGTVRLWDL-ATGKLLRTLTGHTGAVRSVAFSPdGKTLASGSDDGTVRLWDLATGELLRTLTGHTG 373
|
250 260
....*....|....*....|....*.
gi 1720355455 344 EKNFVGLASNGDYIACGSENNSLYLY 369
Cdd:COG2319 374 AVTSVAFSPDGRTLASGSADGTVRLW 399
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
110-369 |
3.25e-31 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 120.90 E-value: 3.25e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 110 LATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGTViqdavdihYPENEMTC-NSKISCISWSSyHKNLL 188
Cdd:cd00200 38 LETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETG--------ECVRTLTGhTSYVSSVAFSP-DGRIL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 189 ASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEA-KANVCCVKFSP 267
Cdd:cd00200 109 SSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSP-DGTFVASSSQDGTIKLWDLRTGKCVATLTGhTGEVNSVAFSP 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 268 SSRyHLAFGCADHCVHYYDLRnTKQPIMVFKGHRKAVSYAKF-VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKN 346
Cdd:cd00200 188 DGE-KLLSSSSDGTIKLWDLS-TGKCLGTLRGHENGVNSVAFsPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVT 265
|
250 260
....*....|....*....|...
gi 1720355455 347 FVGLASNGDYIACGSENNSLYLY 369
Cdd:cd00200 266 SLAWSPDGKRLASGSADGTIRIW 288
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
187-432 |
7.40e-29 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 116.93 E-value: 7.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 187 LLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKF 265
Cdd:COG2319 92 LLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSP-DGKTLASGSADGTVRLWDLATGKLLRTLTGHSGaVTSVAF 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 266 SPSSRYhLAFGCADHCVHYYDLRnTKQPIMVFKGHRKAVSYAKFvS--GEEIVSASTDSQLKLWNVGKPYCLRSFKGHIN 343
Cdd:COG2319 171 SPDGKL-LASGSDDGTVRLWDLA-TGKLLRTLTGHTGAVRSVAF-SpdGKLLASGSADGTVRLWDLATGKLLRTLTGHSG 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 344 EKNFVGLASNGDYIACGSENNSLYLY--YKGLSKTLLTFKFDTVKSVldkdrkeddtnefvsavcwrALS-DGesNVLIA 420
Cdd:COG2319 248 SVRSVAFSPDGRLLASGSADGTVRLWdlATGELLRTLTGHSGGVNSV--------------------AFSpDG--KLLAS 305
|
250
....*....|..
gi 1720355455 421 ANSQGTIKVLEL 432
Cdd:COG2319 306 GSDDGTVRLWDL 317
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
123-329 |
2.79e-26 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 109.62 E-value: 2.79e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 123 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGT-VIQDAVDIHypenemtcNSKISCISWSSYHKnLLASSDYEGTVILWD 201
Cdd:COG2319 204 TGAVRSVAFSPDGKLLASGSADGTVRLWDLATgKLLRTLTGH--------SGSVRSVAFSPDGR-LLASGSADGTVRLWD 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 202 GFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYhLAFGCADH 280
Cdd:COG2319 275 LATGELLRTLTGHSGGVNSVAFSP-DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGaVRSVAFSPDGKT-LASGSDDG 352
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1720355455 281 CVHYYDLrNTKQPIMVFKGHRKAVSYAKFVS-GEEIVSASTDSQLKLWNV 329
Cdd:COG2319 353 TVRLWDL-ATGELLRTLTGHTGAVTSVAFSPdGRTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
208-432 |
1.82e-23 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 99.33 E-value: 1.82e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 208 SKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWSTNLDNSVASIE-AKANVCCVKFSPSSRYhLAFGCADHCVHYYD 286
Cdd:cd00200 2 RRTLKGHTGGVTCVAFS-PDGKLLATGSGDGTIKVWDLETGELLRTLKgHTGPVRDVAASADGTY-LASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 287 LrNTKQPIMVFKGHRKAVSYAKFVSGEEIV-SASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNS 365
Cdd:cd00200 80 L-ETGECVRTLTGHTSYVSSVAFSPDGRILsSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGT 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720355455 366 LYLYYKGLSKTLLTFKFDTvksvldkdrkeddtnEFVSAVCWralsDGESNVLIAANSQGTIKVLEL 432
Cdd:cd00200 159 IKLWDLRTGKCVATLTGHT---------------GEVNSVAF----SPDGEKLLSSSSDGTIKLWDL 206
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
187-429 |
2.48e-23 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 101.14 E-value: 2.48e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 187 LLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEA-KANVCCVKF 265
Cdd:COG2319 50 RLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSP-DGRLLASASADGTVRLWDLATGLLLRTLTGhTGAVRSVAF 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 266 SPSSRYhLAFGCADHCVHYYDLRnTKQPIMVFKGHRKAVSYAKFVS-GEEIVSASTDSQLKLWNVGKPYCLRSFKGHINE 344
Cdd:COG2319 129 SPDGKT-LASGSADGTVRLWDLA-TGKLLRTLTGHSGAVTSVAFSPdGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGA 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 345 KNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTvksvldkdrkeddtnEFVSAVCWraLSDGEsnVLIAANSQ 424
Cdd:COG2319 207 VRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHS---------------GSVRSVAF--SPDGR--LLASGSAD 267
|
....*
gi 1720355455 425 GTIKV 429
Cdd:COG2319 268 GTVRL 272
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
126-328 |
9.26e-23 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 97.41 E-value: 9.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 126 VSSIEFDRDCDYFAIAGVTKKIKVYeygtviqdavDIHYPENEMTCNSK---ISCISWSSYHKnLLASSDYEGTVILWDG 202
Cdd:cd00200 96 VSSVAFSPDGRILSSSSRDKTIKVW----------DVETGKCLTTLRGHtdwVNSVAFSPDGT-FVASSSQDGTIKLWDL 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 203 FTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTNLDNSVASIEAKAN-VCCVKFSPSSRYhLAFGCADHC 281
Cdd:cd00200 165 RTGKCVATLTGHTGEVNSVAFSP-DGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENgVNSVAFSPDGYL-LASGSEDGT 242
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1720355455 282 VHYYDLRnTKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWN 328
Cdd:cd00200 243 IRVWDLR-TGECVQTLSGHTNSVTSLAWSpDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
123-246 |
1.44e-12 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 68.78 E-value: 1.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 123 SSIVSSIEFDRDCDYFAIAGVTKKIKVYEYGTviQDAVDIHYPENEMtcnskISCISWSSYHKnLLASSDYEGTVILWDG 202
Cdd:COG2319 288 SGGVNSVAFSPDGKLLASGSDDGTVRLWDLAT--GKLLRTLTGHTGA-----VRSVAFSPDGK-TLASGSDDGTVRLWDL 359
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1720355455 203 FTGQRSKVYQEHEKRCWSVDFNLmDPKLLASGSDDAKVKLWSTN 246
Cdd:COG2319 360 ATGELLRTLTGHTGAVTSVAFSP-DGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
227-429 |
6.72e-07 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 51.07 E-value: 6.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 227 DPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSY 306
Cdd:COG2319 5 DGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720355455 307 AKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTvk 386
Cdd:COG2319 85 AFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHS-- 162
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1720355455 387 svldkdrkeddtnEFVSAVCWRAlsDGEsnVLIAANSQGTIKV 429
Cdd:COG2319 163 -------------GAVTSVAFSP--DGK--LLASGSDDGTVRL 188
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
204-244 |
1.29e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 39.22 E-value: 1.29e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1720355455 204 TGQRSKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWS 244
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFS-PDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
205-244 |
7.87e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.94 E-value: 7.87e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1720355455 205 GQRSKVYQEHEKRCWSVDFNlMDPKLLASGSDDAKVKLWS 244
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFS-PDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
290-328 |
1.03e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 36.52 E-value: 1.03e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1720355455 290 TKQPIMVFKGHRKAVSYAKFV-SGEEIVSASTDSQLKLWN 328
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSpDGKYLASGSDDGTIKLWD 40
|
|
| |
