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Conserved domains on  [gi|1720412149|ref|XP_030109980|]
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homeobox protein cut-like 2 isoform X9 [Mus musculus]

Protein Classification

CUT and homeodomain domain-containing protein( domain architecture ID 11131078)

CUT and homeodomain domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 820-896 5.25e-32

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


:

Pssm-ID: 460543  Cd Length: 78  Bit Score: 119.62  E-value: 5.25e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  820 MSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREpFVRMQLWLSDPHNVEKL 896
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDERME 76
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 665-738 8.22e-30

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


:

Pssm-ID: 460543  Cd Length: 78  Bit Score: 113.07  E-value: 8.22e-30
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720412149  665 MYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREpFIRMQLWLSDQLGQ 738
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDE 73
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 308-384 1.35e-27

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


:

Pssm-ID: 460543  Cd Length: 78  Bit Score: 106.91  E-value: 1.35e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  308 EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEpFIKMKQFLSDEQNVLAL 384
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDERME 76
Homeodomain pfam00046
Homeodomain;
946-1002 1.74e-14

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 69.07  E-value: 1.74e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRR 1002
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-137 6.01e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 6.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELA----------------------RLEQDIARLEERRRELEERLEELEEELA 326

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720412149   84 ELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLAS 137
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
 
Name Accession Description Interval E-value
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 820-896 5.25e-32

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


Pssm-ID: 460543  Cd Length: 78  Bit Score: 119.62  E-value: 5.25e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  820 MSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREpFVRMQLWLSDPHNVEKL 896
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDERME 76
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 665-738 8.22e-30

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


Pssm-ID: 460543  Cd Length: 78  Bit Score: 113.07  E-value: 8.22e-30
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720412149  665 MYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREpFIRMQLWLSDQLGQ 738
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDE 73
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 308-384 1.35e-27

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


Pssm-ID: 460543  Cd Length: 78  Bit Score: 106.91  E-value: 1.35e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  308 EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEpFIKMKQFLSDEQNVLAL 384
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDERME 76
Homeodomain pfam00046
Homeodomain;
946-1002 1.74e-14

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 69.07  E-value: 1.74e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRR 1002
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 946-1004 1.86e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 60.33  E-value: 1.86e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720412149  946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREM 1004
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 946-1001 1.45e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 57.65  E-value: 1.45e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720412149   946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMR 1001
Cdd:smart00389    2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-137 6.01e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 6.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELA----------------------RLEQDIARLEERRRELEERLEELEEELA 326

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720412149   84 ELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLAS 137
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3-131 5.46e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 5.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    3 NLEKANQRAEAAQREVESLREQLASVNSSIRLaccspqgpsgEKVSFAlcsgpRLEAALASKDREILRLLKDAQQLRHSL 82
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTL----------LNEEAA-----NLRERLESLERRIAATERRLEDLEEQI 847

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720412149   83 QELEEvsanQIADLERQLAAKSEAIEKLQEKLE-AQADYEEIKTELSILR 131
Cdd:TIGR02168  848 EELSE----DIESLAAEIEELEELIEELESELEaLLNERASLEEALALLR 893
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 56-132 1.86e-03

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 39.54  E-value: 1.86e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149   56 RLEAALASKDREILRLLKDAQQLRHSLQELEEVSANQIADLERQLAAKSEAIEKLQeklEAQADYEEIKTELSILRA 132
Cdd:pfam07926    5 SLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQ---ALREELNELKAEIAELKA 78
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
945-1003 3.90e-03

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 39.34  E-value: 3.90e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720412149  945 AKKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRRE 1003
Cdd:COG5576     51 PKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKK 109
 
Name Accession Description Interval E-value
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 820-896 5.25e-32

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


Pssm-ID: 460543  Cd Length: 78  Bit Score: 119.62  E-value: 5.25e-32
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  820 MSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREpFVRMQLWLSDPHNVEKL 896
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDERME 76
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 665-738 8.22e-30

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


Pssm-ID: 460543  Cd Length: 78  Bit Score: 113.07  E-value: 8.22e-30
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720412149  665 MYREVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREpFIRMQLWLSDQLGQ 738
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDE 73
CUT pfam02376
CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in ...
 308-384 1.35e-27

CUT domain; The CUT domain is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, often found downstream of the CUT domain. Multiple copies of the CUT domain can exist in one protein.


Pssm-ID: 460543  Cd Length: 78  Bit Score: 106.91  E-value: 1.35e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  308 EEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVKGKEpFIKMKQFLSDEQNVLAL 384
Cdd:pfam02376    1 DSEELDTKDIADRIKEELKRHKISQAVFAEKVLNRSQGTLSDLLRKPKPWEKLKSGGRT-FIRMYNWLSLPEDERME 76
Homeodomain pfam00046
Homeodomain;
946-1002 1.74e-14

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 69.07  E-value: 1.74e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149  946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRR 1002
Cdd:pfam00046    1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWKR 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 946-1004 1.86e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 60.33  E-value: 1.86e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720412149  946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRREM 1004
Cdd:cd00086      1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 946-1001 1.45e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 57.65  E-value: 1.45e-10
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720412149   946 KKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMR 1001
Cdd:smart00389    2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-137 6.01e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 6.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELA----------------------RLEQDIARLEERRRELEERLEELEEELA 326

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720412149   84 ELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAMKLAS 137
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2-127 6.94e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 6.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    2 TNLEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAAL--ASKDREILRLLKDAQQLR 79
Cdd:COG1579     45 ARLEAAKTELEDLEKEIKRLELEIEEVEARIK----------------------KYEEQLgnVRNNKEYEALQKEIESLK 102

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1720412149   80 HSLQELEEvsanQIADLERQLAAKSEAIEKLQEKLEA-QADYEEIKTEL 127
Cdd:COG1579    103 RRISDLED----EILELMERIEELEEELAELEAELAElEAELEEKKAEL 147
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
3-128 7.47e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 7.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    3 NLEKANQRAEAAQREVESLREQLASVNssiRLaccspqgpsgEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSL 82
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQ---RL----------AEYSWDEIDVASAEREIAELEAELERLDASSDDLAALE 691

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1720412149   83 QELEEVSAnQIADLERQLAAKSEAIEKLQEKLE-AQADYEEIKTELS 128
Cdd:COG4913    692 EQLEELEA-ELEELEEELDELKGEIGRLEKELEqAEEELDELQDRLE 737
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
4-134 9.31e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 9.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASvNSSIRLAccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:COG4913    311 LERLEARLDALREELDELEAQIRG-NGGDRLE--------------------QLEREIERLERELEERERRRARLEALLA 369

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720412149   84 ELE---EVSANQIADLERQLAAKSEAIEKLQEKLE------------AQADYEEIKTELSILRAMK 134
Cdd:COG4913    370 ALGlplPASAEEFAALRAEAAALLEALEEELEALEealaeaeaalrdLRRELRELEAEIASLERRK 435
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
3-132 3.56e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.51  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    3 NLEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSL 82
Cdd:COG4372     32 QLRKALFELDKLQEELEQLREELEQAREELE----------------------QLEEELEQARSELEQLEEELEELNEQL 89

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720412149   83 QELEEvsanQIADLERQLAAKSEAIEKLQEKLEA-QADYEEIKTELSILRA 132
Cdd:COG4372     90 QAAQA----ELAQAQEELESLQEEAEELQEELEElQKERQDLEQQRKQLEA 136
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3-131 5.46e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 5.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    3 NLEKANQRAEAAQREVESLREQLASVNSSIRLaccspqgpsgEKVSFAlcsgpRLEAALASKDREILRLLKDAQQLRHSL 82
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTL----------LNEEAA-----NLRERLESLERRIAATERRLEDLEEQI 847

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720412149   83 QELEEvsanQIADLERQLAAKSEAIEKLQEKLE-AQADYEEIKTELSILR 131
Cdd:TIGR02168  848 EELSE----DIESLAAEIEELEELIEELESELEaLLNERASLEEALALLR 893
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
4-133 6.22e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 6.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcSGPRLEAALASKDREILRLLKD-----AQQL 78
Cdd:COG4717    134 LEALEAELAELPERLEELEERLEELRELEE-------------------ELEELEAELAELQEELEELLEQlslatEEEL 194

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720412149   79 RHSLQELEEVSA------NQIADLERQLAAKSEAIEKLQEKLEAQADYEEIKTELSILRAM 133
Cdd:COG4717    195 QDLAEELEELQQrlaeleEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIA 255
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-132 6.45e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 6.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRLACcspqgpsgEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:COG1196    276 LEELELELEEAQAEEYELLAELARLEQDIARLE--------ERRRELEERLEELEEELAELEEELEELEEELEELEEELE 347

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1720412149   84 ELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQAdyEEIKTELSILRA 132
Cdd:COG1196    348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELE--ELAEELLEALRA 394
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
2-135 9.49e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 9.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    2 TNLEKANQRAEAAQREVESLREQLASVNSSIRlACCSPQGPSGEKVSfalcsgpRLEAALASKDREILRLLKDAQQLRHS 81
Cdd:COG4372     59 EELEQLEEELEQARSELEQLEEELEELNEQLQ-AAQAELAQAQEELE-------SLQEEAEELQEELEELQKERQDLEQQ 130

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720412149   82 LQELEEvsanQIADLERQLAAKSEAIEKLQEKLE-AQADYEEIKTELSILRAMKL 135
Cdd:COG4372    131 RKQLEA----QIAELQSEIAEREEELKELEEQLEsLQEELAALEQELQALSEAEA 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 7-157 1.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    7 ANQRAEAAQREVESLREQLASVNSSIrlaccspqgpsgekvsfalcsgprleAALASKDREILRLLKDAQQLRHSLQELE 86
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKEL--------------------------AALKKEEKALLKQLAALERRIAALARRI 71

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720412149   87 EVSANQIADLERQLAAKSEAIEKLQEKLEAQadyeeiKTELS-ILRAMKLASSTcSLPQTLAKPDDPLLVAK 157
Cdd:COG4942     72 RALEQELAALEAELAELEKEIAELRAELEAQ------KEELAeLLRALYRLGRQ-PPLALLLSPEDFLDAVR 136
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 56-132 1.86e-03

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 39.54  E-value: 1.86e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720412149   56 RLEAALASKDREILRLLKDAQQLRHSLQELEEVSANQIADLERQLAAKSEAIEKLQeklEAQADYEEIKTELSILRA 132
Cdd:pfam07926    5 SLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQ---ALREELNELKAEIAELKA 78
PspA COG1842
Phage shock protein A [Transcription, Signal transduction mechanisms];
56-132 2.02e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];


Pssm-ID: 441447 [Multi-domain]  Cd Length: 217  Bit Score: 40.96  E-value: 2.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149   56 RLEAALASKDREILRLLKDAQQL---------RHSLQELEEVsANQIADLERQLAAKSEAIEKLQEKL-EAQADYEEIKT 125
Cdd:COG1842     55 RLERQLEELEAEAEKWEEKARLAlekgredlaREALERKAEL-EAQAEALEAQLAQLEEQVEKLKEALrQLESKLEELKA 133


                   ....*..
gi 1720412149  126 ELSILRA 132
Cdd:COG1842    134 KKDTLKA 140
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 65-132 2.08e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 2.08e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720412149   65 DREILRLLKDAQQLRHSLQELEEVSAN---QIADLERQLAAKSEAIEKLQEKLE-AQADYEEIKTELSILRA 132
Cdd:COG1579      2 MPEDLRALLDLQELDSELDRLEHRLKElpaELAELEDELAALEARLEAAKTELEdLEKEIKRLELEIEEVEA 73
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 6-132 2.20e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    6 KANQRAEAAQREVESLREQLASVNSSIRLAccspqgpsGEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQEL 85
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQIL--------RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720412149   86 EEVSA---NQIADLERQLAAKSEAIEKLQEKLEAQA-DYEEIKTELSILRA 132
Cdd:TIGR02168  350 KEELEsleAELEELEAELEELESRLEELEEQLETLRsKVAQLELQIASLNN 400
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
3-188 2.34e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    3 NLEKANQRAEAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSL 82
Cdd:COG4372     81 ELEELNEQLQAAQAELAQAQEELESLQEEAE----------------------ELQEELEELQKERQDLEQQRKQLEAQI 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149   83 QELEEVSAN---QIADLERQLAAKSEAIEKLQEKLEAQADyEEIKTELSILR--AMKLASSTCSLPQTLAKPDDPLLVAK 157
Cdd:COG4372    139 AELQSEIAEreeELKELEEQLESLQEELAALEQELQALSE-AEAEQALDELLkeANRNAEKEEELAEAEKLIESLPRELA 217

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1720412149  158 DVFFPTQKFLLEKPALLASPEEDPSEDDSIK 188
Cdd:COG4372    218 EELLEAKDSLEAKLGLALSALLDALELEEDK 248
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 57-118 3.11e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 3.11e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720412149   57 LEAALASKDREILRLLKDAQQLRHSLQELEEvsanQIADLERQLAAKSEAIEKLQEKLEAQA 118
Cdd:COG3883     35 AQAELDALQAELEELNEEYNELQAELEALQA----EIDKLQAEIAEAEAEIEERREELGERA 92
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
4-132 3.63e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 3.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRLAccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:COG4717     97 LEELEEELEELEAELEELREELEKLEKLLQLL--------------------PLYQELEALEAELAELPERLEELEERLE 156

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720412149   84 ELEEVsANQIADLERQLAAKSEAIEKLQEKL---------EAQADYEEIKTELSILRA 132
Cdd:COG4717    157 ELREL-EEELEELEAELAELQEELEELLEQLslateeelqDLAEELEELQQRLAELEE 213
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
945-1003 3.90e-03

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 39.34  E-value: 3.90e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720412149  945 AKKPRVVLAPAEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSRMRRE 1003
Cdd:COG5576     51 PKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKK 109
UPF0242 pfam06785
Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal ...
 56-117 4.08e-03

Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal transmembrane region and a C-terminal coiled-coil.


Pssm-ID: 429117 [Multi-domain]  Cd Length: 194  Bit Score: 39.80  E-value: 4.08e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720412149   56 RLEAALASKDREILRLLKDAQQLRHSLQELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQ 117
Cdd:pfam06785  101 RLEEELSQKEEELRRLTEENQQLQIQLQQISQDFAEFRLESEEQLAEKQLLINEYQQTIEEQ 162
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 4-132 4.55e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRLaccSPQGPSGEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQ 83
Cdd:TIGR02169  760 LKELEARIEELEEDLHKLEEALNDLEARLSH---SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720412149   84 ELEEvsanQIADLERQLAAKSEAIEKLQEKLEA-QADYEEIKTELSILRA 132
Cdd:TIGR02169  837 ELQE----QRIDLKEQIKSIEKEIENLNGKKEElEEELEELEAALRDLES 882
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 4-134 4.70e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 4.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSI---------RLACCSPQGPSGEKVSFALCSGP------RLEA--ALASKDR 66
Cdd:COG3883     53 YNELQAELEALQAEIDKLQAEIAEAEAEIeerreelgeRARALYRSGGSVSYLDVLLGSESfsdfldRLSAlsKIADADA 132

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720412149   67 EILRLLKDAQQlrhSLQELEEVSANQIADLERQLAAKSEAIEKLQEKL-EAQADYEEIKTELSILRAMK 134
Cdd:COG3883    133 DLLEELKADKA---ELEAKKAELEAKLAELEALKAELEAAKAELEAQQaEQEALLAQLSAEEAAAEAQL 198
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
4-119 6.68e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 6.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLAsvnssirlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRhslQ 83
Cdd:COG4913    283 LWFAQRRLELLEAELEELRAELA-----------------------------RLEAELERLEARLDALREELDELE---A 330

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1720412149   84 ELEEVSANQIADLERQLAAKSEAIEKLQEKLEAQAD 119
Cdd:COG4913    331 QIRGNGGDRLEQLEREIERLERELEERERRRARLEA 366
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2-133 7.42e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.77  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    2 TNLEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSgekvsfalcsgprLEAALASKDREILRLLK-------D 74
Cdd:COG3206    226 SQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQ-------------LRAQLAELEAELAELSArytpnhpD 292

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720412149   75 AQQLRHSLQELEE-----------VSANQIADLERQLAAKSEAIEKLQEKL----EAQADYEEIKTELSILRAM 133
Cdd:COG3206    293 VIALRAQIAALRAqlqqeaqrilaSLEAELEALQAREASLQAQLAQLEARLaelpELEAELRRLEREVEVAREL 366
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 4-139 8.04e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.20  E-value: 8.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149    4 LEKANQRAEAAQREVESLREQLASVNSSIRLaccspQGPSGEKVSFALCSGP------RLEA--ALASKDREILRLLKDA 75
Cdd:COG3883     67 IDKLQAEIAEAEAEIEERREELGERARALYR-----SGGSVSYLDVLLGSESfsdfldRLSAlsKIADADADLLEELKAD 141

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720412149   76 Q--------QLRHSLQELEEVSA---NQIADLERQLAAKSEAIEKLQEKleaQADYEEIKTELSILRAMKLASST 139
Cdd:COG3883    142 KaeleakkaELEAKLAELEALKAeleAAKAELEAQQAEQEALLAQLSAE---EAAAEAQLAELEAELAAAEAAAA 213
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 61-132 8.70e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 8.70e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720412149   61 LASKDREILRLLKDAQQLRHSLQELEevsaNQIADLERQLAAKSEAIEKLQEKLE-AQADYEEIKTELSILRA 132
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNLE----SQINDLESKIQNQEKLNQQKDEQIKkLQQEKELLEKEIERLKE 433
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 12-124 9.70e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.14  E-value: 9.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720412149   12 EAAQREVESLREQLASVNSSIRlaccspqgpsgekvsfalcsgpRLEAALASKDREILRLLKDAQQLRHSLQELEEVSAN 91
Cdd:COG1579     92 EALQKEIESLKRRISDLEDEIL----------------------ELMERIEELEEELAELEAELAELEAELEEKKAELDE 149

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1720412149   92 QIADLERQLAAKSEAIEKLQEKLEAQ--ADYEEIK 124
Cdd:COG1579    150 ELAELEAELEELEAEREELAAKIPPEllALYERIR 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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