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Conserved domains on  [gi|1720403612|ref|XP_030108400|]
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microtubule-associated protein 9 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PTZ00121 super family cl31754
MAEBL; Provisional
445-622 9.85e-08

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 9.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  445 IKRIESENLRIQNEQKKAAKREEA-LASFEAWKAMKEKEAKRIAAKKR----LEEKNKKKTEEENAMRKGEALQAFEKWK 519
Cdd:PTZ00121  1410 LKKAAAAKKKADEAKKKAEEKKKAdEAKKKAEEAKKADEAKKKAEEAKkaeeAKKKAEEAKKADEAKKKAEEAKKADEAK 1489
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  520 eKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERK-EALLKQKEKEKINERRK-EELKRAEKKDKDKQ 597
Cdd:PTZ00121  1490 -KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEEKKKADELKKaEELKKAEEKKKAEE 1568
                          170       180
                   ....*....|....*....|....*
gi 1720403612  598 AISEYEKWLEKKERQERIERKQKKR 622
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEAKKAEEAR 1593
 
Name Accession Description Interval E-value
PTZ00121 PTZ00121
MAEBL; Provisional
445-622 9.85e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 9.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  445 IKRIESENLRIQNEQKKAAKREEA-LASFEAWKAMKEKEAKRIAAKKR----LEEKNKKKTEEENAMRKGEALQAFEKWK 519
Cdd:PTZ00121  1410 LKKAAAAKKKADEAKKKAEEKKKAdEAKKKAEEAKKADEAKKKAEEAKkaeeAKKKAEEAKKADEAKKKAEEAKKADEAK 1489
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  520 eKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERK-EALLKQKEKEKINERRK-EELKRAEKKDKDKQ 597
Cdd:PTZ00121  1490 -KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEEKKKADELKKaEELKKAEEKKKAEE 1568
                          170       180
                   ....*....|....*....|....*
gi 1720403612  598 AISEYEKWLEKKERQERIERKQKKR 622
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEAKKAEEAR 1593
CCDC34 pfam13904
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...
510-623 1.69e-06

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.


Pssm-ID: 464032 [Multi-domain]  Cd Length: 221  Bit Score: 49.32  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 510 EALQAFEKWKEKKLEYLKEKTRREKEyERAKKQKEEeavAEKKKDSLTAFEKWSERKEALLKQKEKEKIN----ERRKEE 585
Cdd:pfam13904  52 QPLEAYENWLAAKQRQRQKELQAQKE-EREKEEQEA---ELRKRLAKEKYQEWLQRKARQQTKKREESHKqkaaESASKS 127
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1720403612 586 LKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKKRH 623
Cdd:pfam13904 128 LAKPERKVSQEEAKEVLQEWERKKLEQQQRKREEEQRE 165
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
446-614 1.26e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 47.92  E-value: 1.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 446 KRIESENLRIQNEQKKAAKREEALASfEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRKGEA-LQAFEKWK---EK 521
Cdd:TIGR02794  46 GAVAQQANRIQQQKKPAAKKEQERQK-KLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAaKQAEEKQKqaeEA 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 522 KLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISE 601
Cdd:TIGR02794 125 KAKQAAEAKAKAEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAK 204
                         170
                  ....*....|...
gi 1720403612 602 YEKWLEKKERQER 614
Cdd:TIGR02794 205 AAAEAAAKAEAEA 217
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-629 2.00e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.01  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 446 KRIESENLRIQNEQKKAAKREEALASFEAwkAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRkgEALQAFEKWKEKKLEY 525
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELEELEE--ELEEAEEELEEAEAELAEAEEALLEAEAELA--EAEEELEELAEELLEA 391
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 526 LKEKTRREKEYERAKKQ----KEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISE 601
Cdd:COG1196   392 LRAAAELAAQLEELEEAeealLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                         170       180
                  ....*....|....*....|....*...
gi 1720403612 602 YEKWLEKKERQERIERKQKKRHSFLESE 629
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEA 499
 
Name Accession Description Interval E-value
PTZ00121 PTZ00121
MAEBL; Provisional
445-622 9.85e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 9.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  445 IKRIESENLRIQNEQKKAAKREEA-LASFEAWKAMKEKEAKRIAAKKR----LEEKNKKKTEEENAMRKGEALQAFEKWK 519
Cdd:PTZ00121  1410 LKKAAAAKKKADEAKKKAEEKKKAdEAKKKAEEAKKADEAKKKAEEAKkaeeAKKKAEEAKKADEAKKKAEEAKKADEAK 1489
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  520 eKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERK-EALLKQKEKEKINERRK-EELKRAEKKDKDKQ 597
Cdd:PTZ00121  1490 -KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEEKKKADELKKaEELKKAEEKKKAEE 1568
                          170       180
                   ....*....|....*....|....*
gi 1720403612  598 AISEYEKWLEKKERQERIERKQKKR 622
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEAKKAEEAR 1593
PTZ00121 PTZ00121
MAEBL; Provisional
407-629 5.69e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 5.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  407 QKQPRKQSLEPDKADHIRAAVYQEWLEKKNV--YLHEMHRIKRIESENLRIQNEQKKAA----KREEALASFEAWKAMKE 480
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIeeVMKLYEEEKKMKAEEAKKAEEAKIKAeelkKAEEEKKKVEQLKKKEA 1643
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  481 KEAK-----RIAAKKRLEEKNKKKTEEENAMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEA-------- 547
Cdd:PTZ00121  1644 EEKKkaeelKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaeelkk 1723
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  548 ---VAEKKKDSLTAFEKWSERK--EALLKQKEKEKINERRKEELKRAEKKDKDKQAISEYEkwLEKKERQERIERKQKKR 622
Cdd:PTZ00121  1724 aeeENKIKAEEAKKEAEEDKKKaeEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE--LDEEDEKRRMEVDKKIK 1801

                   ....*..
gi 1720403612  623 HSFLESE 629
Cdd:PTZ00121  1802 DIFDNFA 1808
PTZ00121 PTZ00121
MAEBL; Provisional
346-629 5.99e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 5.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  346 EPAKKANEDRNTKNKKTTNNRVSSASGRLMTSEFLKRSGPTKRSPSAATSSHYLGSLKVLDQKQPRKQSLEPDKADHIRA 425
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  426 AVYQEWLEKKNvYLHEMHRIKRIESENLRIQNEQKKA--AKREEALASFEAWKAMK------EKEAKRIAAKKRLEEKNK 497
Cdd:PTZ00121  1554 AEELKKAEEKK-KAEEAKKAEEDKNMALRKAEEAKKAeeARIEEVMKLYEEEKKMKaeeakkAEEAKIKAEELKKAEEEK 1632
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  498 KKTEEENAMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEK 577
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720403612  578 INERRKEELKRAEKKDKDKQAISEYEKWLEKKERQE-RIERKQKKRHSFLESE 629
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEaKKDEEEKKKIAHLKKE 1765
PRK12704 PRK12704
phosphodiesterase; Provisional
483-591 9.52e-07

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 51.70  E-value: 9.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 483 AKRIAAKKRLEEKNKKKTEEENAMRKGEA------LQAFEKWKEKKLEYLKEKTRREKEYERAKK---QKEE-----EAV 548
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAikkealLEAKEEIHKLRNEFEKELRERRNELQKLEKrllQKEEnldrkLEL 104
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1720403612 549 AEKKKDSLTAFEKWSERKEALLKQKEKEkINERRKEELKRAEK 591
Cdd:PRK12704  105 LEKREEELEKKEKELEQKQQELEKKEEE-LEELIEEQLQELER 146
CCDC34 pfam13904
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...
510-623 1.69e-06

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.


Pssm-ID: 464032 [Multi-domain]  Cd Length: 221  Bit Score: 49.32  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 510 EALQAFEKWKEKKLEYLKEKTRREKEyERAKKQKEEeavAEKKKDSLTAFEKWSERKEALLKQKEKEKIN----ERRKEE 585
Cdd:pfam13904  52 QPLEAYENWLAAKQRQRQKELQAQKE-EREKEEQEA---ELRKRLAKEKYQEWLQRKARQQTKKREESHKqkaaESASKS 127
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1720403612 586 LKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKKRH 623
Cdd:pfam13904 128 LAKPERKVSQEEAKEVLQEWERKKLEQQQRKREEEQRE 165
PTZ00121 PTZ00121
MAEBL; Provisional
345-622 1.86e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 1.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  345 AEPAKKANEDRNTKNKKTTNNRVSSASGRlmTSEFLKRSGPTKRSPSAATSSHYLGSLKVLDQKQPRKQSLEPDKADHIR 424
Cdd:PTZ00121  1172 AEDAKKAEAARKAEEVRKAEELRKAEDAR--KAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEER 1249
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  425 AAVYQEWLEKKNVyLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRleEKNKKKTEEEN 504
Cdd:PTZ00121  1250 NNEEIRKFEEARM-AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK--KADEAKKKAEE 1326
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  505 AMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEE--EAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERR 582
Cdd:PTZ00121  1327 AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKK 1406
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720403612  583 KEELKRAE----------KKDKDKQAISEYEKWLEKKERQERIERKQKKR 622
Cdd:PTZ00121  1407 ADELKKAAaakkkadeakKKAEEKKKADEAKKKAEEAKKADEAKKKAEEA 1456
CCDC34 pfam13904
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...
555-645 1.94e-06

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.


Pssm-ID: 464032 [Multi-domain]  Cd Length: 221  Bit Score: 49.32  E-value: 1.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 555 SLTAFEKWSERKEallKQKEKEKINERRKEELKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKKRHSFLESETHPPW 634
Cdd:pfam13904  53 PLEAYENWLAAKQ---RQRQKELQAQKEEREKEEQEAELRKRLAKEKYQEWLQRKARQQTKKREESHKQKAAESASKSLA 129
                          90
                  ....*....|.
gi 1720403612 635 SPPSRTAPSKV 645
Cdd:pfam13904 130 KPERKVSQEEA 140
PTZ00121 PTZ00121
MAEBL; Provisional
407-621 1.04e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  407 QKQPRKQSLEPDKADHIRAAVYQEWLE--KKNVYLHEMHRIKRIESENLRIQNEQKKAakrEEALASFEAWKAMKEKEAK 484
Cdd:PTZ00121  1267 RRQAAIKAEEARKADELKKAEEKKKADeaKKAEEKKKADEAKKKAEEAKKADEAKKKA---EEAKKKADAAKKKAEEAKK 1343
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  485 RIAAKKRleEKNKKKTEEENAMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEavaEKKKDSLTAFEKWSE 564
Cdd:PTZ00121  1344 AAEAAKA--EAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED---KKKADELKKAAAAKK 1418
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  565 RKEALLKQ-KEKEKINERRK--EELKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKK 621
Cdd:PTZ00121  1419 KADEAKKKaEEKKKADEAKKkaEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
446-614 1.26e-05

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 47.92  E-value: 1.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 446 KRIESENLRIQNEQKKAAKREEALASfEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRKGEA-LQAFEKWK---EK 521
Cdd:TIGR02794  46 GAVAQQANRIQQQKKPAAKKEQERQK-KLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAaKQAEEKQKqaeEA 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 522 KLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISE 601
Cdd:TIGR02794 125 KAKQAAEAKAKAEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAK 204
                         170
                  ....*....|...
gi 1720403612 602 YEKWLEKKERQER 614
Cdd:TIGR02794 205 AAAEAAAKAEAEA 217
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-629 2.00e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.01  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 446 KRIESENLRIQNEQKKAAKREEALASFEAwkAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRkgEALQAFEKWKEKKLEY 525
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELEELEE--ELEEAEEELEEAEAELAEAEEALLEAEAELA--EAEEELEELAEELLEA 391
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 526 LKEKTRREKEYERAKKQ----KEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISE 601
Cdd:COG1196   392 LRAAAELAAQLEELEEAeealLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
                         170       180
                  ....*....|....*....|....*...
gi 1720403612 602 YEKWLEKKERQERIERKQKKRHSFLESE 629
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEA 499
PTZ00121 PTZ00121
MAEBL; Provisional
345-622 2.90e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 2.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  345 AEPAKKANEDRNTKNKKTTNNRVSSASGR---LMTSEFLKRSGPTKRSPSAATSSHYLGSLKVLDQKQPRKQSLEPDKAD 421
Cdd:PTZ00121  1239 AEEAKKAEEERNNEEIRKFEEARMAHFARrqaAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD 1318
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  422 HIRAAVYQ-----EWLEKKNVYLHEMHRIKRIESEnlRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRLEEKN 496
Cdd:PTZ00121  1319 EAKKKAEEakkkaDAAKKKAEEAKKAAEAAKAEAE--AAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  497 KKKTEEENamRKGEALQAFEKWKeKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLtafEKWSERKEALLKQKEKE 576
Cdd:PTZ00121  1397 KKKAEEDK--KKADELKKAAAAK-KKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA---EEAKKAEEAKKKAEEAK 1470
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1720403612  577 KINERRK--EELKRAE----KKDKDKQAISEYEKWLEKKERQERIERKQKKR 622
Cdd:PTZ00121  1471 KADEAKKkaEEAKKADeakkKAEEAKKKADEAKKAAEAKKKADEAKKAEEAK 1522
CCDC34 pfam13904
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ...
441-608 2.92e-05

Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.


Pssm-ID: 464032 [Multi-domain]  Cd Length: 221  Bit Score: 45.85  E-value: 2.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 441 EMHRIKRIESENLRIQNEQKKaaKREEALASFEAWKAMKEKEAKRiaaKKRLEEKNKKKTEEENAMRKGEALQAFEKWKE 520
Cdd:pfam13904  28 SLDSSSQSSSLTYARKLEGLK--LERQPLEAYENWLAAKQRQRQK---ELQAQKEEREKEEQEAELRKRLAKEKYQEWLQ 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 521 KKlEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTA----FEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDK 596
Cdd:pfam13904 103 RK-ARQQTKKREESHKQKAAESASKSLAKPERKVSQEEakevLQEWERKKLEQQQRKREEEQREQLKKEEEEQERKQLAE 181
                         170
                  ....*....|..
gi 1720403612 597 QAiseYEKWLEK 608
Cdd:pfam13904 182 KA---WQKWMKN 190
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
431-623 4.13e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.89  E-value: 4.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  431 WLEKKNVYLHEMHRI---KRIESENLRIQNEQKK-----AAKREEALASFE--AWKAMKEKEAKRIAAKKRLEEKNKKKT 500
Cdd:pfam02463  110 YINGKNVTKKEVAELlesQGISPEAYNFLVQGGKieiiaMMKPERRLEIEEeaAGSRLKRKKKEALKKLIEETENLAELI 189
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  501 EEENAMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKInE 580
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKL-A 268
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1720403612  581 RRKEELKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKKRH 623
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
429-619 4.18e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 4.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 429 QEWLEKKNVYLHEMHrIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRK 508
Cdd:COG4717    55 ADELFKPQGRKPELN-LKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 509 GEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEaVAEKKKDSLTAFEKWSERKEALLKQ--KEKEKINERR---K 583
Cdd:COG4717   134 LEALEAELAELPERLEELEERLEELRELEEELEELEAE-LAELQEELEELLEQLSLATEEELQDlaEELEELQQRLaelE 212
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1720403612 584 EELKRAEKKDKD-KQAISEYEKWLEKKERQERIERKQ 619
Cdd:COG4717   213 EELEEAQEELEElEEELEQLENELEAAALEERLKEAR 249
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
451-622 5.66e-05

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 45.68  E-value: 5.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 451 ENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRKgeALQAFEKWKEKK-----LEY 525
Cdd:pfam13868  83 EEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQA--EWKELEKEEEREederiLEY 160
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 526 LKEKTRREKEYERAKKQKEEEAVAEKKKDS---LTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISE- 601
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRaqqEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQa 240
                         170       180
                  ....*....|....*....|.
gi 1720403612 602 YEKWLEKKERQERIERKQKKR 622
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEE 261
CCDC47 pfam07946
PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of ...
527-598 1.21e-04

PAT complex subunit CCDC47; This family represents CCDC47 proteins which are a component of the PAT complex, an endoplasmic reticulum (ER)-resident membrane multiprotein complex that facilitates multi-pass membrane proteins insertion into membranes. The PAT complex, formed by CCDC47 and Asterix proteins, acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs), releasing its substrates upon correct folding, and is needed for optimal biogenesis of multi-pass membrane proteins. CCDC47 is required to maintain the stability of Asterix. CCDC47 is associated with various membrane-associated processes and is component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. It is also involved in the regulation of calcium ion homeostasis in the ER, being also required for proper protein degradation via the ERAD (ER-associated degradation) pathway.


Pssm-ID: 462322  Cd Length: 323  Bit Score: 44.48  E-value: 1.21e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720403612 527 KEKTRREKEYERAKKQKEEEAVAEKKkdsltafekwsERKEALLKQKEKEKINERRKEELKRAEKKDKDKQA 598
Cdd:pfam07946 261 KAKKTREEEIEKIKKAAEEERAEEAQ-----------EKKEEAKKKEREEKLAKLSPEEQRKYEEKERKKEQ 321
PTZ00121 PTZ00121
MAEBL; Provisional
346-629 1.44e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  346 EPAKKANEDRNTKNKKTTNNRVSSASGRLMTSEFLKRSGPTKRSPSAATSShylgslkvldQKQPRKQSLEPDKADHIRA 425
Cdd:PTZ00121  1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKK----------AEEAKKAEEAKKKAEEAKK 1471
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  426 AvyqEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAA----KREEALASFEAWKAMKEKEAKRiaAKKRLEEKNKKKTE 501
Cdd:PTZ00121  1472 A---DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeakkKADEAKKAEEAKKADEAKKAEE--AKKADEAKKAEEKK 1546
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  502 EENAMRKGEALQAFEKwKEKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINER 581
Cdd:PTZ00121  1547 KADELKKAEELKKAEE-KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL 1625
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720403612  582 RKEE----------LKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKKRHSFLESE 629
Cdd:PTZ00121  1626 KKAEeekkkveqlkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
441-622 3.19e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 3.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 441 EMHRIKriESENLRIQNEQKKAAKREEalasFEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRKGEaLQAFEKWKE 520
Cdd:pfam17380 373 EISRMR--ELERLQMERQQKNERVRQE----LEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQRE-VRRLEEERA 445
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 521 KKLEYLK-EKTRREKEYERAKKQKEEeavAEKKKDSLTAFEKWSERKEAL--------LKQKEKEKINERRKEELKRAEK 591
Cdd:pfam17380 446 REMERVRlEEQERQQQVERLRQQEEE---RKRKKLELEKEKRDRKRAEEQrrkilekeLEERKQAMIEEERKRKLLEKEM 522
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1720403612 592 KDKDKQAISEYEKWLEKKERQERIERKQKKR 622
Cdd:pfam17380 523 EERQKAIYEEERRREAEEERRKQQEMEERRR 553
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
446-629 3.24e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 3.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 446 KRIESENLRIQNEQKKAAKREEALasFEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRkgEALQAFEKWKEKKLEY 525
Cdd:COG1196   267 AELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEERRRELEERLEELEEELA--ELEEELEELEEELEEL 342
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 526 LKEKTRREKEYERAKKQKE--EEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISEYE 603
Cdd:COG1196   343 EEELEEAEEELEEAEAELAeaEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422
                         170       180
                  ....*....|....*....|....*.
gi 1720403612 604 KWLEKKERQERIERKQKKRHSFLESE 629
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEALEEAA 448
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
520-610 5.16e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 5.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 520 EKKLEYLK-EKTRREKE-----YERAKKQKEEEAVAEKKKDSLTAfeKWSERKEALLKQKEKEKINERRKEELKRAEKKD 593
Cdd:COG0542   417 ERRLEQLEiEKEALKKEqdeasFERLAELRDELAELEEELEALKA--RWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494
                          90
                  ....*....|....*..
gi 1720403612 594 KDKQAISEYEKWLEKKE 610
Cdd:COG0542   495 AELEEELAELAPLLREE 511
PRK12705 PRK12705
hypothetical protein; Provisional
525-631 7.70e-04

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.39  E-value: 7.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 525 YLKEKTRREKEYERAKKQKEEEAVAEKKkdsltafEKWSERKEALLK-QKEKEKINERRKEELKRAEKK--DKDKQAISE 601
Cdd:PRK12705   24 LLKKRQRLAKEAERILQEAQKEAEEKLE-------AALLEAKELLLReRNQQRQEARREREELQREEERlvQKEEQLDAR 96
                          90       100       110
                  ....*....|....*....|....*....|
gi 1720403612 602 YEKWLEKKERQERIERKQKKRHSFLESETH 631
Cdd:PRK12705   97 AEKLDNLENQLEEREKALSARELELEELEK 126
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
425-621 8.03e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 8.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  425 AAVYQEWLEKKNVYLHEMH---RIKRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRL---EEKNKK 498
Cdd:pfam02463  162 AAGSRLKRKKKEALKKLIEeteNLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLklnEERIDL 241
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  499 KTEEENAMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQ------ 572
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKlkesek 321
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720403612  573 ----KEKEKINERRKEELKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKK 621
Cdd:pfam02463  322 ekkkAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEE 374
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
408-593 8.26e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.10  E-value: 8.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 408 KQPRKQSLEPDKADHIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKR------------EEALASFEAW 475
Cdd:PRK09510   66 RQQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAakqaalkqkqaeEAAAKAAAAA 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 476 KAMKEKEAKRI--AAKKRLEEKNKKKTEEENAMRKGEALQAFEKWKEKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKK 553
Cdd:PRK09510  146 KAKAEAEAKRAaaAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAAAEAKA 225
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1720403612 554 dsltAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKD 593
Cdd:PRK09510  226 ----AAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEVDD 261
PTZ00121 PTZ00121
MAEBL; Provisional
451-624 1.93e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  451 ENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRLEEKNKKKTEEENA--MRKGEALQAFEKWKEKKLEYLKE 528
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAhfARRQAAIKAEEARKADELKKAEE 1288
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  529 KtrreKEYERAKKQKEEEAVAEKKKdsltafeKWSERKEALLKQKEKEKINERRKEELKRAE-KKDKDKQAISEYEKWLE 607
Cdd:PTZ00121  1289 K----KKADEAKKAEEKKKADEAKK-------KAEEAKKADEAKKKAEEAKKKADAAKKKAEeAKKAAEAAKAEAEAAAD 1357
                          170
                   ....*....|....*..
gi 1720403612  608 KKERQERIERKQKKRHS 624
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKE 1374
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
476-629 2.62e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 476 KAMKEKEAKRIAAKKRLEEKNKKKTEEENAMRKGEALQA-FEKWKEK--KLEYLKEKTRREKEYERAKKQ-KEEEAVAEK 551
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAeLEELREEleKLEKLLQLLPLYQELEALEAElAELPERLEE 150
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720403612 552 KKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISEYEKWLEKKERQERIERKQKKRHSFLESE 629
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
446-629 2.67e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.11  E-value: 2.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  446 KRIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKRIAAKKRLEEKN--KKKTEEENAMRKGEALQAFEKWKEKKL 523
Cdd:pfam02463  251 EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEKEL 330
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612  524 EYLKEK-TRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISEY 602
Cdd:pfam02463  331 KKEKEEiEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
                          170       180       190
                   ....*....|....*....|....*....|..
gi 1720403612  603 EKWLEKKE-----RQERIERKQKKRHSFLESE 629
Cdd:pfam02463  411 LELARQLEdllkeEKKEELEILEEEEESIELK 442
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
444-625 3.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.13  E-value: 3.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 444 RIKRIESENLRIQNEQKKAAKREEALAsfEAWKAMKEKEAKRIAAKKRLEEKNKKK-----TEEENAMRKGEALQAFEKW 518
Cdd:COG4942    70 RIRALEQELAALEAELAELEKEIAELR--AELEAQKEELAELLRALYRLGRQPPLAlllspEDFLDAVRRLQYLKYLAPA 147
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 519 KEKKLEYLKEKTRREKeyerakkQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQA 598
Cdd:COG4942   148 RREQAEELRADLAELA-------ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQ 220
                         170       180
                  ....*....|....*....|....*...
gi 1720403612 599 -ISEYEKWLEKKERQERIERKQKKRHSF 625
Cdd:COG4942   221 eAEELEALIARLEAEAAAAAERTPAAGF 248
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
448-613 5.24e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 39.86  E-value: 5.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 448 IESENLRIQNEQKKAAKREEALASFEAwkAMKEKEAKRIAAKKRLEeknkkkteeenAMRKGEALQAFEKWKEKKLEylK 527
Cdd:COG2268   186 LDALGRRKIAEIIRDARIAEAEAERET--EIAIAQANREAEEAELE-----------QEREIETARIAEAEAELAKK--K 250
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 528 EKTRREKEYERAKKQKE-EEAVAEKKKDSLTAFEKWSERKEALLKQKEKekinERRKEELKRAEKK--DKDKQAIseyek 604
Cdd:COG2268   251 AEERREAETARAEAEAAyEIAEANAEREVQRQLEIAEREREIELQEKEA----EREEAELEADVRKpaEAEKQAA----- 321

                  ....*....
gi 1720403612 605 wlEKKERQE 613
Cdd:COG2268   322 --EAEAEAE 328
RRP36 pfam06102
rRNA biogenesis protein RRP36; RRP36 is involved in the early processing steps of the pre-rRNA.
519-621 5.81e-03

rRNA biogenesis protein RRP36; RRP36 is involved in the early processing steps of the pre-rRNA.


Pssm-ID: 461829 [Multi-domain]  Cd Length: 158  Bit Score: 37.92  E-value: 5.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 519 KEKKLEYLKEKTRREKEYERAKKQKEEEAVAEKKKDsltAFEKWSERKEAL--LKQKEKEKINE-RRKEELKRAEKKDKD 595
Cdd:pfam06102  58 RKKEIEELKKQLKKTKDPEEKEELKRTLQSMESRLK---AKKRKDREREVLkeHKKEEKEKVKQgKKPFYLKKSEKKKLL 134
                          90       100
                  ....*....|....*....|....*.
gi 1720403612 596 KQAisEYEKWLEKKERQERIERKQKK 621
Cdd:pfam06102 135 LKE--KFEELKKSGKLDKAIEKKRKK 158
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
528-622 9.51e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 38.67  E-value: 9.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720403612 528 EKTRREKEYERAKKQKEEEAVAEKKKDSLTAFEKWSERKEALLKQKEKEKINERRKEELKRAEKKDKDKQAISEYEKWLE 607
Cdd:TIGR02794  74 EQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEEAAKQAE 153
                          90
                  ....*....|....*
gi 1720403612 608 KKERQERIERKQKKR 622
Cdd:TIGR02794 154 EEAKAKAAAEAKKKA 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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