|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
14-204 |
6.30e-84 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 245.62 E-value: 6.30e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADN 93
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 94 cghyaqvqmsdktgdrdwacdrrflkfhkyeedldtktrkdwlpKLEVQSYD-LDWTGAPAAVVIGGETHGVSLESLQLA 172
Cdd:cd18106 81 --------------------------------------------NLPVQPYDsIDYCSGPIVLVIGGETHGVSPEAYKLA 116
|
170 180 190
....*....|....*....|....*....|..
gi 1720367193 173 ESTGGKRLLIPVVPGVDSLNSAMAASILLFEG 204
Cdd:cd18106 117 HSTGGSRVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
13-211 |
9.05e-41 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 139.95 E-value: 9.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 13 PLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVnnvewetvpnhlppdtRVyvad 92
Cdd:COG0566 115 PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVA----------------RV---- 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 93 ncghyaqvqmsdktgdRDWACDRRFLKFHKY---------EEDLdtktrkdwlpklevqsYDLDWTGaPAAVVIGGETHG 163
Cdd:COG0566 175 ----------------TNLADALEELKEAGFwvvgtdldgEASL----------------YEVDLPG-PVALVLGNEGKG 221
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1720367193 164 VSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRIK 211
Cdd:COG0566 222 LSRLVLEACD----ELVRIPMAGGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
13-202 |
1.13e-29 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 107.62 E-value: 1.13e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 13 PLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPP-DTRVYV 90
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEaGYAVVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 91 ADncghyaqvqmsdkTGDRDWacdrrflkfhkyeedldtktrkdwlpklevqsYDLDWTGaPAAVVIGGETHGVSLESLQ 170
Cdd:pfam00588 81 TS-------------LGGKSL--------------------------------YEIDFPK-KVALVFGNEGTGLSNEVLE 114
|
170 180 190
....*....|....*....|....*....|..
gi 1720367193 171 LAEstggKRLLIPVVPGVDSLNSAMAASILLF 202
Cdd:pfam00588 115 LCD----RLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
13-208 |
3.61e-14 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 68.91 E-value: 3.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 13 PLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVnnveweTVPNHLPPDTR----- 87
Cdd:TIGR00186 90 PFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLA------RVTNLSRTITKlkesg 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 88 --VYVADncghyaqvqmsdktGDRDWAcdrrflkfhKYEEDLDtktrkdwlpklevqsydldwtgAPAAVVIGGETHGVS 165
Cdd:TIGR00186 164 fwTVGTD--------------LDAQDT---------LYQVKLT----------------------KPLALVVGNEGEGVS 198
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1720367193 166 LESLQLAEStggkRLLIPVVPGVDSLNSAMAASILLFEGKRQL 208
Cdd:TIGR00186 199 RLIKENCDF----LIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
145-207 |
2.75e-08 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 52.30 E-value: 2.75e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720367193 145 DLDWTgAPAAVVIGGETHGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 207
Cdd:PRK11081 107 EIDYT-RPTCILMGQEKTGISQEALALAD----QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
14-204 |
6.30e-84 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 245.62 E-value: 6.30e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADN 93
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 94 cghyaqvqmsdktgdrdwacdrrflkfhkyeedldtktrkdwlpKLEVQSYD-LDWTGAPAAVVIGGETHGVSLESLQLA 172
Cdd:cd18106 81 --------------------------------------------NLPVQPYDsIDYCSGPIVLVIGGETHGVSPEAYKLA 116
|
170 180 190
....*....|....*....|....*....|..
gi 1720367193 173 ESTGGKRLLIPVVPGVDSLNSAMAASILLFEG 204
Cdd:cd18106 117 HSTGGSRVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
14-203 |
5.82e-48 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 154.12 E-value: 5.82e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPP-DTRVYVAD 92
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEaGYKVVAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 93 ncghyaqvqmsdktgdrdwacdrrflkfhkyeedldtktrkdwlPKLEVQSYDLDWTGaPAAVVIGGETHGVSLESLQLA 172
Cdd:cd18095 81 --------------------------------------------LDGGSSLYDLDLPK-PVALVLGNEGNGLSDELLELC 115
|
170 180 190
....*....|....*....|....*....|.
gi 1720367193 173 EstggKRLLIPVVPGVDSLNSAMAASILLFE 203
Cdd:cd18095 116 D----KRVTIPMSGGVESLNVAVAAAILLYE 142
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
13-211 |
9.05e-41 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 139.95 E-value: 9.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 13 PLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVnnvewetvpnhlppdtRVyvad 92
Cdd:COG0566 115 PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVA----------------RV---- 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 93 ncghyaqvqmsdktgdRDWACDRRFLKFHKY---------EEDLdtktrkdwlpklevqsYDLDWTGaPAAVVIGGETHG 163
Cdd:COG0566 175 ----------------TNLADALEELKEAGFwvvgtdldgEASL----------------YEVDLPG-PVALVLGNEGKG 221
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1720367193 164 VSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRIK 211
Cdd:COG0566 222 LSRLVLEACD----ELVRIPMAGGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
14-207 |
3.02e-31 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 111.52 E-value: 3.02e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVpnhlppdtrvyvadn 93
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASSEETL--------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 94 cghyaqvqmsdktgdrdwacdrRFLKFHKYEEDLDTktrkdwlPKLEVQSYDLDWTGaPAAVVIGGETHGVSLESLQLAe 173
Cdd:cd18104 66 ----------------------AWLKENKIRILATT-------PKAEKLYYEADLRG-PIAIVVGSESEGLSEFWLKAA- 114
|
170 180 190
....*....|....*....|....*....|....
gi 1720367193 174 stgGKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 207
Cdd:cd18104 115 ---DERVRIPMAGQADSLNVSVAAAILLYEALRQ 145
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
13-202 |
1.13e-29 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 107.62 E-value: 1.13e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 13 PLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPP-DTRVYV 90
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEaGYAVVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 91 ADncghyaqvqmsdkTGDRDWacdrrflkfhkyeedldtktrkdwlpklevqsYDLDWTGaPAAVVIGGETHGVSLESLQ 170
Cdd:pfam00588 81 TS-------------LGGKSL--------------------------------YEIDFPK-KVALVFGNEGTGLSNEVLE 114
|
170 180 190
....*....|....*....|....*....|..
gi 1720367193 171 LAEstggKRLLIPVVPGVDSLNSAMAASILLF 202
Cdd:pfam00588 115 LCD----RLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
14-203 |
4.52e-29 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 105.70 E-value: 4.52e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHlPPDTRVYVADN 93
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTVDPYNPKVVQASMGSIFRVQIHYTDLPALLAEL-KKAFPVYGADL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 94 CGHYAqvqmsdktgdrdwacdrrflkfhkYEEDLDTktrkdwlpklevqsydldwtgaPAAVVIGGETHGVSLESLQLAE 173
Cdd:cd18109 80 DGENL------------------------YEFTLPE----------------------KGILVMGNEGHGISPEVLKLLT 113
|
170 180 190
....*....|....*....|....*....|.
gi 1720367193 174 stggKRLLIPVVP-GVDSLNSAMAASILLFE 203
Cdd:cd18109 114 ----HRLTIPRYGkGAESLNVAVATAILLSE 140
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
15-203 |
2.64e-24 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 93.83 E-value: 2.64e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 15 VLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPI--VNNVEwETVPNHLPPDTRVYVAd 92
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYerVDNFE-EYLKSLKEEGYPLIGL- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 93 ncghyaqvqMSDKTGDRdwacdrrflkfhkyeedldtktrkdwlpkleVQSYDLDWTGaPAAVVIGGETHGVSLESLQLA 172
Cdd:cd18082 79 ---------ELTDGSIP-------------------------------LSEFKFKKPK-KIALIFGNERSGLSPELLALC 117
|
170 180 190
....*....|....*....|....*....|.
gi 1720367193 173 EstggKRLLIPVVPGVDSLNSAMAASILLFE 203
Cdd:cd18082 118 D----YTVHIPMSGKNSSLNVSVATGIALYE 144
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
14-203 |
3.99e-18 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 77.81 E-value: 3.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNnvewetVPNHLPPDTRVYVADN 93
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVR------VPSNRELEDWVEARKA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 94 CGHYAQVQMSDKTGDrdwacdrrflkfhkyeedldtktrkdwlpkleVQSYDLDWTGaPAAVVIGGETHGVSLESLQLAE 173
Cdd:cd18107 75 RGTPLQLVGTDEHGD--------------------------------HQIADHDFTR-PTLLLIGNETAGLSAAWRELCD 121
|
170 180 190
....*....|....*....|....*....|
gi 1720367193 174 STGGkrllIPVVPGVDSLNSAMAASILLFE 203
Cdd:cd18107 122 ETVS----IPMAGSASSLNAACAASIFLYE 147
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
14-203 |
5.91e-18 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 77.04 E-value: 5.91e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAwEPKVLRAGMGAHFQVPI--VNNVE-----------Wetvp 79
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKrRSAPL-TPTVAKASAGALEHLPIarVTNLAraleelkeagfW---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 80 nhlppdtrVYVADncghyaqvqmsdktgdrdwacdrrflkfHKYEEDLdtktrkdwlpklevqsYDLDWTGaPAAVVIGG 159
Cdd:cd18103 76 --------IYGAD----------------------------GEAEKSL----------------YDVDLTG-PLALVLGS 102
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1720367193 160 ETHGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFE 203
Cdd:cd18103 103 EGKGLRRLVLKNCD----FLVKIPMAGKVDSLNVSVAAGIILYE 142
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
13-208 |
3.61e-14 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 68.91 E-value: 3.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 13 PLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVnnveweTVPNHLPPDTR----- 87
Cdd:TIGR00186 90 PFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLA------RVTNLSRTITKlkesg 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 88 --VYVADncghyaqvqmsdktGDRDWAcdrrflkfhKYEEDLDtktrkdwlpklevqsydldwtgAPAAVVIGGETHGVS 165
Cdd:TIGR00186 164 fwTVGTD--------------LDAQDT---------LYQVKLT----------------------KPLALVVGNEGEGVS 198
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1720367193 166 LESLQLAEStggkRLLIPVVPGVDSLNSAMAASILLFEGKRQL 208
Cdd:TIGR00186 199 RLIKENCDF----LIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
14-203 |
1.96e-13 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 64.89 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLtkgCVDAWEP---KVLRAGMGAHfqvpivNNVEWETVPnHLPPDTRVYV 90
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIYL---CGYTPTPphpKVAKTALGAE------ESVPWEHFE-DTLEAVRALK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 91 ADNcghYAQVQMSDKTGDRDWacdrrflkfhkyeedldtktrkdwlpklevqsYDLDWtGAPAAVVIGGETHGVSLESLQ 170
Cdd:cd18097 71 ARG---YTIIALETTENSVPL--------------------------------HEARL-PRPLALVLGNEVRGVSPEVLA 114
|
170 180 190
....*....|....*....|....*....|...
gi 1720367193 171 LAESTggkrLLIPVVPGVDSLNSAMAASILLFE 203
Cdd:cd18097 115 LCDAV----VEIPMFGRKNSLNVAVAAAVALYE 143
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
14-208 |
1.92e-10 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 57.48 E-value: 1.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLtkgcvdAWEPKVLRAG----MGAHfqvpivnnvEWETVpnHLPPDTrvy 89
Cdd:cd18092 17 LTVVLENVHDPHNASAVLRTCDAFGVQDVHV------IEPKNKFKKNrgvaMGAD---------KWLDV--HRHDST--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 90 vaDNCghYAQVQMSdktGDRDWACDrrflkFHKYEEDLDtktrkdwlpklevqsyDLDWTGaPAAVVIGGETHGVSLESL 169
Cdd:cd18092 77 --EEC--LAALKEQ---GYRIVATS-----LSPDAVPLD----------------ELDYTR-PTALVFGNEKDGVSEEAL 127
|
170 180 190
....*....|....*....|....*....|....*....
gi 1720367193 170 QLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 208
Cdd:cd18092 128 AAAD----ERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
14-201 |
5.04e-09 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 53.29 E-value: 5.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 14 LVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAhfqvpivnnVEwetvpnHLPpdtrVYVADN 93
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGA---------LE------LMP----IYSVDN 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 94 CGHYaqVQMSDKTGdrdW----ACDrrflkfhkyeeDLDTKTRKDWLPKLEVQSydlDWTGAPAAVVIGGETHGVSLESL 169
Cdd:cd18105 62 LASF--LKSSKENG---WkvvgTSA-----------PPSASSDKKTIPANELSE---LLLEKPTILVLGNEGRGLRTNIK 122
|
170 180 190
....*....|....*....|....*....|....*..
gi 1720367193 170 QLAESTggkrLLIPV-----VPGVDSLNSAMAASILL 201
Cdd:cd18105 123 NLCDYL----VSIPGgrsaeNPGVDSLNVSVAAGILL 155
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
145-207 |
2.75e-08 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 52.30 E-value: 2.75e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720367193 145 DLDWTgAPAAVVIGGETHGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 207
Cdd:PRK11081 107 EIDYT-RPTCILMGQEKTGISQEALALAD----QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
24-208 |
1.44e-07 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 48.99 E-value: 1.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 24 PGNLGTILRSAAGAGCSKVLLtkgcvdawEP--------KVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVAdncg 95
Cdd:cd18094 10 PQNTGNIARTCAATGARLHLI--------EPlgfslddkRLKRAGLDYWDHVDLTVHDSWEAFLEALPPGRLFLFT---- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 96 hyaqvqmsdKTGDRdwacdrRFLKFhKYEEDldtktrkDWLpklevqsydldwtgapaavVIGGETHGVSLEslqLAEST 175
Cdd:cd18094 78 ---------TKGTK------PYTDF-DFKPG-------DYL-------------------VFGRESTGLPEE---ILDAF 112
|
170 180 190
....*....|....*....|....*....|...
gi 1720367193 176 GGKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 208
Cdd:cd18094 113 PDRRLRIPMRPKVRSLNLSNSVAIVLYEALRQL 145
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
24-208 |
2.36e-07 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 48.49 E-value: 2.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 24 PGNLGTILRSAAGAGCsKVLLTKGCVDAWEPKVL-RAGMGAHFQVPIVNNVEWETVPNHLPPDtRVYVADNCG--HYAQV 100
Cdd:COG0219 12 PQNTGNIIRLCAATGA-RLHLIEPLGFSLDDKKLkRAGLDYWELVDLTVHDSWEAFLEALPGG-RLFLFTTKGtkPYTDV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 101 QmsdktgdrdwacdrrflkfhkYEEDldtktrkDWLpklevqsydldwtgapaavVIGGETHGVSLEslqLAESTGGKRL 180
Cdd:COG0219 90 D---------------------YQPG-------DVL-------------------LFGRETAGLPEE---VLAAPADQRL 119
|
170 180
....*....|....*....|....*...
gi 1720367193 181 LIPVVPGVDSLNSAMAASILLFEGKRQL 208
Cdd:COG0219 120 RIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
9-207 |
6.81e-04 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 39.56 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 9 HHTLPLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVnnveweTVPN------HL 82
Cdd:PRK11181 91 SLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLI------RVTNlartmrML 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 83 pPDTRVYVADNCGhyaqvqmsdktgdrdwacdrrflkfhkyEEDLDTktrkdwlpklevqsYDLDWTGaPAAVVIGgeth 162
Cdd:PRK11181 165 -QEKNIWIVGTAG----------------------------EADHTL--------------YQSKLTG-PLALVMG---- 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1720367193 163 gvsleslqlAESTGGKRLL---------IPVVPGVDSLNSAMAASILLFEGKRQ 207
Cdd:PRK11181 197 ---------AEGEGMRRLTrehcdelisIPMAGSVSSLNVSVATGICLFEAVRQ 241
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
24-203 |
9.72e-04 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 38.25 E-value: 9.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 24 PGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFqvpivnnvewetvpnhlppdtrvyVADNCGHYAQVqmS 103
Cdd:cd18093 11 PGNIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAED------------------------VLENAKVYDTL--E 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720367193 104 DKTGDRDW--ACDRRflKFHKYEEDLDTKTRKDWLPKLEvqsydldwTGAPAAVVIGGETHGVSLESLQLAEstggKRLL 181
Cdd:cd18093 65 EALADCDLvvATTAR--PRGLRRPLLTPRELAELLKEHA--------AGGKVALVFGREDSGLTNEELALCD----LLVT 130
|
170 180
....*....|....*....|..
gi 1720367193 182 IPVVPGVDSLNSAMAASILLFE 203
Cdd:cd18093 131 IPTNPEYPSLNLAQAVAIVLYE 152
|
|
| |
