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Conserved domains on  [gi|1720366833|ref|XP_030102020|]
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heparan sulfate glucosamine 3-O-sulfotransferase 3B1 isoform X1 [Mus musculus]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
27-187 1.77e-35

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 125.15  E-value: 1.77e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833  27 ISAMSKDTKLIVVVRDPVTRAISDYTQT----LSKRPDIPSFESLTFrnrsaglidtSWSAIQIGLYAKHLEPWLRHFPL 102
Cdd:pfam00685  86 KSLWDPNAKIIYLVRNPKDVAVSYYHFFrmakLLKAPGTPFEFVEDF----------LNGKVNCGSYFDHVKGWWKLRPP 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833 103 GQMLFVSGERLVSDPAGELRRVQDFLGLKR-----IITDKHFYFNQTKGFPCLKKAE-----GSGKPHCLGKTKgraHPT 172
Cdd:pfam00685 156 GNILFLRYEDLKKDPRGEIKKIAEFLGIPLteeelDKIVKHLSFENMKGNPCLNYSKlpkevSPFFRKGLVGDW---KNY 232

                         170
                  ....*....|....*
gi 1720366833 173 IAREVLRQLRDFYRP 187
Cdd:pfam00685 233 FTPEQAEKFDEIYQE 247
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
27-187 1.77e-35

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 125.15  E-value: 1.77e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833  27 ISAMSKDTKLIVVVRDPVTRAISDYTQT----LSKRPDIPSFESLTFrnrsaglidtSWSAIQIGLYAKHLEPWLRHFPL 102
Cdd:pfam00685  86 KSLWDPNAKIIYLVRNPKDVAVSYYHFFrmakLLKAPGTPFEFVEDF----------LNGKVNCGSYFDHVKGWWKLRPP 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833 103 GQMLFVSGERLVSDPAGELRRVQDFLGLKR-----IITDKHFYFNQTKGFPCLKKAE-----GSGKPHCLGKTKgraHPT 172
Cdd:pfam00685 156 GNILFLRYEDLKKDPRGEIKKIAEFLGIPLteeelDKIVKHLSFENMKGNPCLNYSKlpkevSPFFRKGLVGDW---KNY 232

                         170
                  ....*....|....*
gi 1720366833 173 IAREVLRQLRDFYRP 187
Cdd:pfam00685 233 FTPEQAEKFDEIYQE 247
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
27-187 1.77e-35

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 125.15  E-value: 1.77e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833  27 ISAMSKDTKLIVVVRDPVTRAISDYTQT----LSKRPDIPSFESLTFrnrsaglidtSWSAIQIGLYAKHLEPWLRHFPL 102
Cdd:pfam00685  86 KSLWDPNAKIIYLVRNPKDVAVSYYHFFrmakLLKAPGTPFEFVEDF----------LNGKVNCGSYFDHVKGWWKLRPP 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833 103 GQMLFVSGERLVSDPAGELRRVQDFLGLKR-----IITDKHFYFNQTKGFPCLKKAE-----GSGKPHCLGKTKgraHPT 172
Cdd:pfam00685 156 GNILFLRYEDLKKDPRGEIKKIAEFLGIPLteeelDKIVKHLSFENMKGNPCLNYSKlpkevSPFFRKGLVGDW---KNY 232

                         170
                  ....*....|....*
gi 1720366833 173 IAREVLRQLRDFYRP 187
Cdd:pfam00685 233 FTPEQAEKFDEIYQE 247
Sulfotransfer_3 pfam13469
Sulfotransferase family;
12-130 4.33e-13

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 64.23  E-value: 4.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720366833  12 EKTPSYFvtrEAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKrpDIPSFEslTFRNRSAGLIDTSWSAIQIGLYAk 91
Cdd:pfam13469  63 DKSPSHL---FHLDLLLKAFPDAKFIHLHRDPVDTVISSYCSLFGF--TLSSYS--TAFLRDIGLALARWSRAYERLMA- 134

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1720366833  92 hlepWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGL 130
Cdd:pfam13469 135 ----ARARVPPGRFLDVRYEDLVADPEGTLRRILEFLGL 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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