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Conserved domains on  [gi|1720364834|ref|XP_030101573|]
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nuclear receptor corepressor 1 isoform X32 [Mus musculus]

Protein Classification

nuclear receptor corepressor 1( domain architecture ID 15502538)

nuclear receptor corepressor 1 (NCOR1) is a transcriptional coregulatory protein which assists nuclear receptors in the down regulation of gene expression

CATH:  1.20.58.1880
Gene Ontology:  GO:0006355|GO:0003700|GO:0003677
PubMed:  8882580|20084085
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GPS2_interact super family cl24372
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 9.48e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


The actual alignment was detected with superfamily member pfam15784:

Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 105.71  E-value: 9.48e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1720364834  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 636-679 6.11e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.11e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1720364834  636 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 679
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
MDN1 super family cl34967
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 720-919 9.04e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5271:

Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.17  E-value: 9.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  720 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 793
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  794 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 872
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720364834  873 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 919
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 450-492 1.26e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


:

Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.26e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1720364834  450 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 492
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 9.48e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 105.71  E-value: 9.48e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1720364834  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 636-679 6.11e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.11e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1720364834  636 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 679
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 636-679 1.32e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.32e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1720364834  636 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 679
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
636-681 2.10e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.10e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1720364834   636 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 681
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 720-919 9.04e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.17  E-value: 9.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  720 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 793
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  794 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 872
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720364834  873 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 919
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 754-919 6.70e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 48.05  E-value: 6.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  754 EAAKSSEDSSENAASRGNTEPVAELEATT--DPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEEcGAE 831
Cdd:PRK13108   283 GALRGSEYVVDEALEREPAELAAAAVASAasAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE-STP 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  832 GSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKErDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSADEGV 911
Cdd:PRK13108   362 AVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA-PEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDD 440


                   ....*...
gi 1720364834  912 DGEPERQR 919
Cdd:PRK13108   441 PAEPDGIR 448
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 450-492 1.26e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.26e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1720364834  450 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 492
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
448-493 3.90e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 3.90e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1720364834   448 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 493
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 450-489 5.17e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.17e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1720364834  450 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 489
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 692-914 6.90e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.90  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  692 KQKASRKP---------REERDVSQCESVAStvSAQEDEDIEASNEEENPEDSEG-AENSSDTES---APSPSPVEAAKS 758
Cdd:TIGR00927  613 KEQLSRRPvakvmalgdLSKGDVAEAEHTGE--RTGEEGERPTEAEGENGEESGGeAEQEGETETkgeNESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  759 SEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDP 838
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGET 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  839 PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSAD---------E 909
Cdd:TIGR00927  771 EAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAEnqgeakqdeK 850


                   ....*
gi 1720364834  910 GVDGE 914
Cdd:TIGR00927  851 GVDGG 855
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 150-239 9.48e-27

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 105.71  E-value: 9.48e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  150 FGSKHEAPSSPLAGqPCGDDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPV 229
Cdd:pfam15784    1 YYPQVEAISPTLPS-PEGQDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPPS 79

                           90
                   ....*....|
gi 1720364834  230 EQKHRSIVQI 239
Cdd:pfam15784   80 ESKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 636-679 6.11e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.14  E-value: 6.11e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1720364834  636 RWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYK 679
Cdd:pfam00249    3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 636-679 1.32e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.36  E-value: 1.32e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1720364834  636 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYK 679
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
636-681 2.10e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 2.10e-10
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1720364834   636 RWTEEEMEVAKKGLVEHG-RNWAAIAKMVGTKSEAQCKNFYFNYKRR 681
Cdd:smart00717    3 EWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 720-919 9.04e-06

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 51.17  E-value: 9.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  720 DEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAE------LEATTDPAPcASPSSA 793
Cdd:COG5271    454 DEEEEAEAELDTEEDTESAEEDADGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAeetsadDGADTDAAA-DPEDSD 532

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  794 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSS-VLDPPAPTKADSVDPEMQvpENTASKGEGDAKERDLES 872
Cdd:COG5271    533 EDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAeTEDATENADADETEESAD--ESEEAEASEDEAAEEEEA 610

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720364834  873 TSEKTEArDEDVVVAEQIERPEPQSDDDSS----ATCSADEGVDGEPERQR 919
Cdd:COG5271    611 DDDEADA-DADGAADEEETEEEAAEDEAAEpetdASEAADEDADAETEAEA 660
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 695-914 4.69e-05

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 48.86  E-value: 4.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  695 ASRKPREERDVSQCESVASTVSAQEDEDIEAS-----NEEENPEDSEGAENSSDTE------SAPSPSPVEAAKSSEDSS 763
Cdd:COG5271    525 AADPEDSDEDALEDETEGEENAPGSDQDADETdepeaTAEEDEPDEAEAETEDATEnadadeTEESADESEEAEASEDEA 604

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  764 ENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKP------AERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVL- 836
Cdd:COG5271    605 AEEEEADDDEADADADGAADEEETEEEAAEDEAAEPetdaseAADEDADAETEAEASADESEEEAEDESETSSEDAEEDa 684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  837 -DPPAPTKADSVDPEM---------QVPENTASKGEGDAKERDLESTSEKTEARDE---------DVVVAEQIERPEPQS 897
Cdd:COG5271    685 dAAAAEASDDEEETEEadedaetasEEADAEEADTEADGTAEEAEEAAEEAESADEeaaslpdeaDAEEEAEEAEEAEED 764

                          250
                   ....*....|....*..
gi 1720364834  898 DDDSSATCSADEGVDGE 914
Cdd:COG5271    765 DADGLEEALEEEKADAE 781
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 754-919 6.70e-05

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 48.05  E-value: 6.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  754 EAAKSSEDSSENAASRGNTEPVAELEATT--DPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEEcGAE 831
Cdd:PRK13108   283 GALRGSEYVVDEALEREPAELAAAAVASAasAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGE-STP 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  832 GSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKErDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSADEGV 911
Cdd:PRK13108   362 AVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAA-PEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDD 440


                   ....*...
gi 1720364834  912 DGEPERQR 919
Cdd:PRK13108   441 PAEPDGIR 448
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 450-492 1.26e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 41.41  E-value: 1.26e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 1720364834  450 WTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTK 492
Cdd:cd00167      2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 709-916 3.03e-04

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 46.16  E-value: 3.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  709 ESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPApcA 788
Cdd:COG5271    561 ATAEEDEPDEAEAETEDATENADADETEESADESEEAEASEDEAAEEEEADDDEADADADGAADEEETEEEAAEDEA--A 638

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  789 SPSSAVPTtkpAERESVEAQVTDSASAETAEPMDVDHEEcgaegssVLDPPAPTKADSVDPEMQVPENTASKGEGDAKER 868
Cdd:COG5271    639 EPETDASE---AADEDADAETEAEASADESEEEAEDESE-------TSSEDAEEDADAAAAEASDDEEETEEADEDAETA 708

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1720364834  869 DLESTSEKTEArDEDVVVAEQIERPEPQSDDDSSATcSADEGVDGEPE 916
Cdd:COG5271    709 SEEADAEEADT-EADGTAEEAEEAAEEAESADEEAA-SLPDEADAEEE 754
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 723-879 3.11e-04

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 45.74  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  723 IEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNT------------EPVAELEATTDPAPCASP 790
Cdd:PRK13108   273 ILAPKGREAPGALRGSEYVVDEALEREPAELAAAAVASAASAVGPVGPGEpnqpddvaeavkAEVAEVTDEVAAESVVQV 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  791 SSAVPTTKPAERESVEAQVTDSASAET-AEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASKGEGDakeRD 869
Cdd:PRK13108   353 ADRDGESTPAVEETSEADIEREQPGDLaGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPA---KP 429

                          170
                   ....*....|
gi 1720364834  870 LESTSEKTEA 879
Cdd:PRK13108   430 DELAVAGPGD 439
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
448-493 3.90e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 40.28  E-value: 3.90e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*..
gi 1720364834   448 NVWTDHEKEIFKDKFIQHP-KNFGLIASYLERKSVPDCVLYYYLTKK 493
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 450-489 5.17e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 39.79  E-value: 5.17e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1720364834  450 WTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYY 489
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 692-867 5.64e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 45.08  E-value: 5.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  692 KQKASRKPREERDVSQCESVASTVSAQ----EDEDIEASNEEENPEDSEGAENSSDTESAPSPSP-----VEAAKSSEDS 762
Cdd:PRK08691   387 KETAAKKPQPRPEAETAQTPVQTASAAampsEGKTAGPVSNQENNDVPPWEDAPDEAQTAAGTAQtsaksIQTASEAETP 466

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  763 SENAASRgNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEgssvlDPPAPT 842
Cdd:PRK08691   467 PENQVSK-NKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYGFPDNDCPPEDGAE-----IPPPDW 540

                          170       180
                   ....*....|....*....|....*
gi 1720364834  843 kadsvdpEMQVPENTASKGEGDAKE 867
Cdd:PRK08691   541 -------EHAAPADTAGGGADEEAE 558
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 735-935 7.79e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 7.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  735 SEGAENSSDTESAPSPSPVEAAKSSEDSS----------------ENAASRGNTEPVAELEATTDPA-PCASPSSAVPTT 797
Cdd:PHA03307    58 GAAACDRFEPPTGPPPGPGTEAPANESRStptwslstlapasparEGSPTPPGPSSPDPPPPTPPPAsPPPSPAPDLSEM 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  798 KPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENT-ASKGEGDAKERDLESTSek 876
Cdd:PHA03307   138 LRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTpPAAASPRPPRRSSPISA-- 215

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720364834  877 tEARDEDVVVAEQIERPEPQSDDDSSATCSADEGVDGEPERQRvfPMDAKPSLLTPPGS 935
Cdd:PHA03307   216 -SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL--PRPAPITLPTRIWE 271
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 450-493 9.54e-04

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 9.54e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1720364834  450 WTDHEKEIFKDKFIQHPKNFGLI-ASYLERKSVPDCVLYYYLTKK 493
Cdd:cd11661      2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 714-916 1.81e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 43.85  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  714 TVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPcaSPSSA 793
Cdd:COG5271    266 GTPDTDDEATDDADGLEAAEDDALDAELTAAQAADPESDDDADDSTLAALEGAAEDTEIATADELAAADDEDD--DDSAA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  794 VPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASKGEGDAKERDLEST 873
Cdd:COG5271    344 EDAAEEAATAEDSAAEDTQDAEDEAAGEAADESEGADTDAAADEADAAADDSADDEEASADGGTSPTSDTDEEEEEADED 423

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1720364834  874 SEKTEARDEdvvvAEQIERPEPQSDDDSSATCSADEGVDGEPE 916
Cdd:COG5271    424 ASAGETEDE----STDVTSAEDDIATDEEADSLADEEEEAEAE 462
PHA03169 PHA03169
hypothetical protein; Provisional
 692-883 2.38e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.04  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  692 KQKASRKPREERDVS-----QCESVASTVSAQEDEDIEASNEE---ENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSS 763
Cdd:PHA03169    37 RGTAARAAKPAPPAPttsgpQVRAVAEQGHRQTESDTETAEESrhgEKEERGQGGPSGSGSESVGSPTPSPSGSAEELAS 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  764 ----ENAASRGNTEPVAELEATTDPAPCASPSSAVPTT---KPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVL 836
Cdd:PHA03169   117 glspENTSGSSPESPASHSPPPSPPSHPGPHEPAPPEShnpSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSE 196

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1720364834  837 DP-PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDED 883
Cdd:PHA03169   197 TPtSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREG 244
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 637-684 3.07e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 38.06  E-value: 3.07e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1720364834  637 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKnFYFNYKRRHNL 684
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCF-DRWRRKLNPKI 47
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 753-916 3.15e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 42.66  E-value: 3.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  753 VEAAKSSEDSsenAASRGNtEPVAELEATTDPAPCA-----SPSSAVPTTKPAEresvEAQVTDSASAETAEPMDVDHEE 827
Cdd:PRK13108   273 ILAPKGREAP---GALRGS-EYVVDEALEREPAELAaaavaSAASAVGPVGPGE----PNQPDDVAEAVKAEVAEVTDEV 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  828 CGAEGSSVLD-----PPAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSS 902
Cdd:PRK13108   345 AAESVVQVADrdgesTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIP 424

                          170
                   ....*....|....
gi 1720364834  903 ATCSADEGVDGEPE 916
Cdd:PRK13108   425 DPAKPDELAVAGPG 438
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 716-916 5.56e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 42.31  E-value: 5.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  716 SAQEDEDIEASNEEENPED---------SEGAENSSDTEsapspSPVEAAKSSEDSSENAASRGNTEpvaelEATTDPAP 786
Cdd:COG5271    645 SEAADEDADAETEAEASADeseeeaedeSETSSEDAEED-----ADAAAAEASDDEEETEEADEDAE-----TASEEADA 714

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  787 CASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDppAPTKADSVDPEMQVPENTASKGEGDAK 866
Cdd:COG5271    715 EEADTEADGTAEEAEEAAEEAESADEEAASLPDEADAEEEAEEAEEAEEDD--ADGLEEALEEEKADAEEAATDEEAEAA 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720364834  867 ERDLESTSEKTEARDEDVVVAEQIE--------RPEPQSDDDSSATCSADEGVDGEPE 916
Cdd:COG5271    793 AEEKEKVADEDQDTDEDALLDEAEAdeeedldgEDEETADEALEDIEAGIAEDDEEDD 850
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 692-914 6.90e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.90  E-value: 6.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  692 KQKASRKP---------REERDVSQCESVAStvSAQEDEDIEASNEEENPEDSEG-AENSSDTES---APSPSPVEAAKS 758
Cdd:TIGR00927  613 KEQLSRRPvakvmalgdLSKGDVAEAEHTGE--RTGEEGERPTEAEGENGEESGGeAEQEGETETkgeNESEGEIPAERK 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  759 SEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDP 838
Cdd:TIGR00927  691 GEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGET 770

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  839 PAPTKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTEARDEDVVVAEQIERPEPQSDDDSSATCSAD---------E 909
Cdd:TIGR00927  771 EAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAEnqgeakqdeK 850


                   ....*
gi 1720364834  910 GVDGE 914
Cdd:TIGR00927  851 GVDGG 855
rne PRK10811
ribonuclease E; Reviewed
 701-860 7.41e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 7.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  701 EERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEA 780
Cdd:PRK10811   854 QVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITE 933

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  781 TTDPAPCASPSSAVPTTKPAERESVEAQVTDSASAETAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASK 860
Cdd:PRK10811   934 SDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEH 1013
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 719-917 9.07e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 41.54  E-value: 9.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  719 EDEDIEASNEEENPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVAELEATTDPAPCASPSSAVpttK 798
Cdd:COG5271    514 TSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADETEE---S 590

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  799 PAERESVEAQVTDSASAETAEPMDVDheecgAEGSSVLDppaptKADSVDPEMQVPENTASKGEGDAKERDLESTSEKTE 878
Cdd:COG5271    591 ADESEEAEASEDEAAEEEEADDDEAD-----ADADGAAD-----EEETEEEAAEDEAAEPETDASEAADEDADAETEAEA 660

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1720364834  879 ARDEDVV-VAEQIERPEPQSDDDSSATcSADEGVDGEPER 917
Cdd:COG5271    661 SADESEEeAEDESETSSEDAEEDADAA-AAEASDDEEETE 699
motB PRK12799
flagellar motor protein MotB; Reviewed
 718-860 9.56e-03

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 40.85  E-value: 9.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720364834  718 QEDEDIEASNEEE---NPEDSEGAENSSDTESAPSPSPVEAAKSSEDSSENAASRGNTEPVA-------ELEATTDPAPC 787
Cdd:PRK12799   267 QSQHDIEHENLDNralDIEKATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVipssvttQSATTTQASAV 346

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720364834  788 ASPSSAVPTTKPAERESVEAQVTDSASAEtAEPMDVDHEECGAEGSSVLDPPAPTKADSVDPEMQVPENTASK 860
Cdd:PRK12799   347 ALSSAGVLPSDVTLPGTVALPAAEPVNMQ-PQPMSTTETQQSSTGNITSTANGPTTSLPAAPASNIPVSPTSR 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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