|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
3.39e-89 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 286.69 E-value: 3.39e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 90 YQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
2.92e-61 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 206.70 E-value: 2.92e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 93 TLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
7.04e-61 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 205.13 E-value: 7.04e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 93 TLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
2.36e-37 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 138.81 E-value: 2.36e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 76 IHNLSILVKQIKFYYQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 1720363745 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
258-1079 |
1.66e-22 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 105.91 E-value: 1.66e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 258 AKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEseLSRYKERLH 337
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLR--LEELREELE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 338 DIEFYKARVEELKEDNQVLLETktmLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Cdd:TIGR02168 243 ELQEELKEAEEELEELTAELQE---LEEKLEELRLEvselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 414 TLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEELRSTADSAAGS---- 489
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL-EAELEELESRLEELEEQLETLRSKVAQLELQiasl 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 490 TSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQ--NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTV 567
Cdd:TIGR02168 399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 568 SSLRQRSQISAEARV-KDIEKENKILHESIKEtcgklskIEFEKRQMKKELELYKEKGERAEELENELNHLGKENeLLQK 646
Cdd:TIGR02168 479 AAERELAQLQARLDSlERLQENLEGFSEGVKA-------LLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGR-LQAV 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 647 KITNLKITCEKLETLEQENS--------------ELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES 712
Cdd:TIGR02168 551 VVENLNAAKKAIAFLKQNELgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 713 LKCASMRMAQLQLENKELESEKEQLRKGlelmRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEME 792
Cdd:TIGR02168 631 LDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 793 NQTLQKSLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Cdd:TIGR02168 707 LEELEEELEQLRKeleeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 869 LFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQS 948
Cdd:TIGR02168 787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEE 866
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 949 TDDSryklLESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEdd 1028
Cdd:TIGR02168 867 LIEE----LESELEA-LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID-- 939
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 1029 kwgrESQEATREllKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1079
Cdd:TIGR02168 940 ----NLQERLSE--EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
581-1373 |
1.26e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 102.83 E-value: 1.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 581 RVKDIEKENKIlhESIKETCGKLSKIEFE-KRQMKKeLELYKEKGERAEELENELNHLGKENELLQKKitnlkitcEKLE 659
Cdd:TIGR02168 171 KERRKETERKL--ERTRENLDRLEDILNElERQLKS-LERQAEKAERYKELKAELRELELALLVLRLE--------ELRE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 660 TLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRM-AQLQLENKELESEKEQLR 738
Cdd:TIGR02168 240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 739 KGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENK 818
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRAT 898
Cdd:TIGR02168 397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 899 IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD-----EQSTDDSRYKL-----LESKLESTLKKS 968
Cdd:TIGR02168 475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlsELISVDEGYEAaieaaLGGRLQAVVVEN 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 969 LEIKEEKIAALE-------ARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIP------------------- 1022
Cdd:TIGR02168 555 LNAAKKAIAFLKqnelgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddldna 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1023 --------------------------VSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1076
Cdd:TIGR02168 635 lelakklrpgyrivtldgdlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1077 NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQvenstlnsqstslmNQNAQLLIQQSSLENENESIMKEREDLKSLYDAL 1156
Cdd:TIGR02168 715 EQLRKELEELSRQISALRKDLARLEAEVEQLE--------------ERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1157 IKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKG----QLEDLEKMIKTEQEKMllESKN 1232
Cdd:TIGR02168 781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAaterRLEDLEEQIEELSEDI--ESLA 858
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1233 HEVVASEYKKlcgenDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDitstklnnqcEL 1312
Cdd:TIGR02168 859 AEIEELEELI-----EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR----------EK 923
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 1313 LSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKL 1373
Cdd:TIGR02168 924 LAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
2.00e-21 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 92.34 E-value: 2.00e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDAS--LRIHNLSILVKQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 94 LQQLIM-MPLPDILIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1224 |
1.66e-20 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 98.98 E-value: 1.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 610 KRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 690 ESLEKENSQLDEENLELRRSVESLKcasmrmaqlqLENKELEsekeqlrkglelmrasfKKTERLEvSYQGLDTENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK----------KEIEELE-----------------EKVKELK-ELKEKAEEYIKLS 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE----KENKRLRQQA 845
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeakaKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 846 EIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELvKRATIDIKTlVTLREDLVSEKLKTQQMNNDL 925
Cdd:PRK03918 380 RLTGLTPEKLEKELEELEKAKEEIEEEISKITA---RIGELKKEIKEL-KKAIEELKK-AKGKCPVCGRELTEEHRKELL 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 926 EKLTHELEKIGLNKERLLHDEqstddSRYKLLESKLESTLKKSLE-IKEEKIAALEARLEESTN-YNQQlrhELKTVKKN 1003
Cdd:PRK03918 455 EEYTAELKRIEKELKEIEEKE-----RKLRKELRELEKVLKKESElIKLKELAEQLKELEEKLKkYNLE---ELEKKAEE 526
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1004 YEALKQRQDEERMVQSSIpvsgeddkwgresQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN-NNLQAQ 1082
Cdd:PRK03918 527 YEKLKEKLIKLKGEIKSL-------------KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEER 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1083 ILALQ---RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESIMKEREDLKSLYDAliKD 1159
Cdd:PRK03918 594 LKELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKYSE--EE 660
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1160 HEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQE 1224
Cdd:PRK03918 661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
250-875 |
5.53e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 97.43 E-value: 5.53e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 250 SVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSARMYRDEL-----DALREKAVRVDK 324
Cdd:TIGR02168 224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK----LEELRLEVSELEEEieelqKELYALANEISR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 325 LESELSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02168 300 LEQQKQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 397 ERDMDRKKIEELmEENMTLEMAQKQSMDESL-HLGWELEQ-ISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTK 474
Cdd:TIGR02168 380 QLETLRSKVAQL-ELQIASLNNEIERLEARLeRLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 475 TVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILEN-------------EIIQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAA 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 542 IET-LRENSErqiKILEQENEHLNQTVSSLRQ----RSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKE 616
Cdd:TIGR02168 539 IEAaLGGRLQ---AVVVENLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 617 -------------------LELYKEKGERAE---------------------------ELENELNHLGKENELLQKKITN 650
Cdd:TIGR02168 616 kalsyllggvlvvddldnaLELAKKLRPGYRivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAE 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 651 LKITCEKLET--------LEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES---------- 712
Cdd:TIGR02168 696 LEKALAELRKeleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEleerleeaee 775
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 713 -LKCASMRMAQLQLENKELESEKEQLRKGL--------ELMRASFKKTERLEVSYQGLD---TENQRLQKALENSNKKIQ 780
Cdd:TIGR02168 776 eLAEAEAEIEELEAQIEQLKEELKALREALdelraeltLLNEEAANLRERLESLERRIAateRRLEDLEEQIEELSEDIE 855
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 781 QLESELQDLEMENQTLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Cdd:TIGR02168 856 SLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932
|
730
....*....|....*
gi 1720363745 861 NLEKENKTLFKEINV 875
Cdd:TIGR02168 933 GLEVRIDNLQERLSE 947
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
705-1378 |
1.76e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 95.89 E-value: 1.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 705 ELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTE--RLEVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:TIGR02168 197 ELERQLKSLE----RQAEKAERYKELKAELRELELALLVLRLEELREEleELQEELKEAEEELEELTAELQELEEKLEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 783 ESELQDLEMENQTLQKSLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELYALAN---EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 863 EKENKTLFKEinvykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL 942
Cdd:TIGR02168 350 KEELESLEAE----------LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 943 LHD----EQSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQ 1018
Cdd:TIGR02168 420 QQEieelLKKLEEAELKELQAELE-ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1019 SSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATlqAEKQALKTQLKQLETQNNNLQAQILALQRQ--------- 1089
Cdd:TIGR02168 499 ENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA--AIEAALGGRLQAVVVENLNAAKKAIAFLKQnelgrvtfl 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1090 --------------TVSLQEQN------------------------------TTLQTQNAKL------------------ 1107
Cdd:TIGR02168 577 pldsikgteiqgndREILKNIEgflgvakdlvkfdpklrkalsyllggvlvvDDLDNALELAkklrpgyrivtldgdlvr 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1108 ----------QVENSTLNsQSTSLMNQNAQLLIQQS---SLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEY 1174
Cdd:TIGR02168 657 pggvitggsaKTNSSILE-RRREIEELEEKIEELEEkiaELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1175 ESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLED----LEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRL 1250
Cdd:TIGR02168 736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEelaeAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1251 NYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQ 1330
Cdd:TIGR02168 816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 1720363745 1331 IQTLMLQNRTLLEQNMESKDLFHvEQRqyiDKLNELRRQKEKLEEKIM 1378
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELE-ELR---EKLAQLELRLEGLEVRID 939
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
529-1229 |
3.35e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 95.12 E-value: 3.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 529 KDLMKEKAQLEKTI---ETLRENSERQIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIKET 599
Cdd:TIGR02168 235 EELREELEELQEELkeaEEELEELTAELQELEEKLEELRLEVSELEEEIEElqkelyALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 600 CGKLSKIEFEKRQMKKELELYKEkgeRAEELENELNHLGKENELLQKKITNLKITCEKLETLEQE-NSELERENRKFKKT 678
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAE---ELAELEEKLEELKEELESLEAELEELEAELEELESRLEElEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 679 LDSFKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSY 758
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEEL-----LKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRL--------EQLEKENK---SLE---QET 824
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlsELISVDEGyeaAIEaalGGR 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 825 SQ--LEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKEnkelVKRATIDIK 902
Cdd:TIGR02168 547 LQavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK----LRKALSYLL 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 903 TLVTLREDLvseklktQQMNNDLEKLTHELEKIGLNKERLlhdeqSTDDSRYKLLESKLESTLKKSLEIKE--EKIAALE 980
Cdd:TIGR02168 623 GGVLVVDDL-------DNALELAKKLRPGYRIVTLDGDLV-----RPGGVITGGSAKTNSSILERRREIEEleEKIEELE 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 981 ARLEESTNYNQQLRHELKTVKKNYEALKQRQDE-------------------ERMVQSSIPVSGEDDKWGRESQEATREL 1041
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELEElsrqisalrkdlarleaevEQLEERIAQLSKELTELEAEIEELEERL 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1042 LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1121
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1122 mnqNAQLLIQQSSLENENESIMKEREDLKSLYDALikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDR 1201
Cdd:TIGR02168 851 ---SEDIESLAAEIEELEELIEELESELEALLNER----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923
|
730 740 750
....*....|....*....|....*....|.
gi 1720363745 1202 YNQLLKQKGQLEDLEKMIK---TEQEKMLLE 1229
Cdd:TIGR02168 924 LAQLELRLEGLEVRIDNLQerlSEEYSLTLE 954
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
6.42e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 93.59 E-value: 6.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 181 MSQEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHflphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEmerdmdrKKIEELMEENMTLEMAqK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE-------KRLEELEERHELYEEA-K 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 421 QSMDESLHL-----GWELEQISRTSELAEAPQKSLGHEVNELTsSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILK 495
Cdd:PRK03918 369 AKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 496 VEKENQRLNKKVEIleneiiqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQR 573
Cdd:PRK03918 448 EHRKELLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKEL 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 574 SQISAEARVKDIEKENKiLHESIKEtcgKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKI 653
Cdd:PRK03918 509 EEKLKKYNLEELEKKAE-EYEKLKE---KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 654 TCekLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELrrsveslkcasmrmaqlqlenKELESE 733
Cdd:PRK03918 585 ES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL---------------------AETEKR 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 734 KEQLRKGLELMRASF--KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLE 811
Cdd:PRK03918 642 LEELRKELEELEKKYseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE 721
|
...
gi 1720363745 812 QLE 814
Cdd:PRK03918 722 RVE 724
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
309-1209 |
8.67e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.59 E-value: 8.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 309 RDELDALREKAVRVDKLESELSRYKERLH----DIEFYKARVEELKEDNQ-VLLETKTMLEDQLEGTRARsdkLHELEKE 383
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRrereKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQ---LASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTL---EMAQKQSMDESLHLgwELEQISRTSELAEAPQKslghevneltss 460
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEA--EIASLERSIAEKERELE------------ 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 461 kllklEMENQsLTKTVEELRSTAdsaagstSKILKVEKENQRLNKKVEILENEIIQEKQSLQncqnlskDLMKEKAQLEK 540
Cdd:TIGR02169 319 -----DAEER-LAKLEAEIDKLL-------AEIEELEREIEEERKRRDKLTEEYAELKEELE-------DLRAELEEVDK 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 541 TIETLRENSERQIKILEQENEHLNqtvSSLRQRSQISAEARVKDIEKENkiLHESIKETCGKLSKIEFEKrqmkkelely 620
Cdd:TIGR02169 379 EFAETRDELKDYREKLEKLKREIN---ELKRELDRLQEELQRLSEELAD--LNAAIAGIEAKINELEEEK---------- 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 621 KEKGERAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELEREnrkfkktldsfknltfqLESLEKENSQLD 700
Cdd:TIGR02169 444 EDKALEIKKQEWKLEQLAADLSKYEQELYDLK---EEYDRVEKELSKLQRE-----------------LAEAEAQARASE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 701 EENLELRRSVESLK--------------------------CASMRMAQLQLENKELESEKEQLRKGLELMRASF-----K 749
Cdd:TIGR02169 504 ERVRGGRAVEEVLKasiqgvhgtvaqlgsvgeryataievAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFlplnkM 583
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 750 KTERLEVSYQGLD----------TENQRLQKA---------LENSNKKIQQLESELQDLEMENQTLQKS------LEELK 804
Cdd:TIGR02169 584 RDERRDLSILSEDgvigfavdlvEFDPKYEPAfkyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSgamtggSRAPR 663
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLK 884
Cdd:TIGR02169 664 GGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLE 740
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 885 ELEKENKELVKRATIDIKTLVTLREDLvseklktQQMNNDLEKLTHELEKIglnkerllhdEQSTDDSRYKLLESKLESt 964
Cdd:TIGR02169 741 ELEEDLSSLEQEIENVKSELKELEARI-------EELEEDLHKLEEALNDL----------EARLSHSRIPEIQAELSK- 802
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 965 LKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRqdeermvqssipvsgeddkwgRESQEATRELLKV 1044
Cdd:TIGR02169 803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ---------------------IKSIEKEIENLNG 861
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1045 KDRliEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQ 1124
Cdd:TIGR02169 862 KKE--ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK---IEELEAQIEKKRKRL----SELKAKLEALEEE 932
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1125 NAQLLIQQSSLENENESIMKErEDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQ 1204
Cdd:TIGR02169 933 LSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
|
....*
gi 1720363745 1205 LLKQK 1209
Cdd:TIGR02169 1012 YEKKK 1016
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-904 |
9.84e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.59 E-value: 9.84e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD----------------ARSARMYRDELDAL 315
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrvkekigeleaeiASLERSIAEKEREL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 316 REKAVRVDKLESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMe 395
Cdd:TIGR02169 318 EDAEERLAKLEAEIDKLLAEIEELE---REIEEERKRRDKLTEEYAELKEELEDLRAE---LEEVDKEFAETRDELKDY- 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 396 merdmdRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKslghEVNELTSSKLLKLEMENQSLTKT 475
Cdd:TIGR02169 391 ------REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN----ELEEEKEDKALEIKKQEWKLEQL 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 476 VEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENE--IIQEKQ------------SLQNCQNLSKDLMKEKAQLEKT 541
Cdd:TIGR02169 461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQarASEERVrggraveevlkaSIQGVHGTVAQLGSVGERYATA 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 542 IETLREN------------SERQIKILEQENEH------LNQTVSSLRQRSqISAEARVKDI--------EKENKILHES 595
Cdd:TIGR02169 541 IEVAAGNrlnnvvveddavAKEAIELLKRRKAGratflpLNKMRDERRDLS-ILSEDGVIGFavdlvefdPKYEPAFKYV 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 596 IKETcGKLSKIEFEKRQMKK------ELELYKEKG---------------------------ERAEELENELNHLGKENE 642
Cdd:TIGR02169 620 FGDT-LVVEDIEAARRLMGKyrmvtlEGELFEKSGamtggsraprggilfsrsepaelqrlrERLEGLKRELSSLQSELR 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 643 LLQKKITNLKITCE----KLETLEQENSELERENRKFKKTLDSFK-----------NLTFQLESLEKENSQLDEENLELR 707
Cdd:TIGR02169 699 RIENRLDELSQELSdasrKIGEIEKEIEQLEQEEEKLKERLEELEedlssleqeieNVKSELKELEARIEELEEDLHKLE 778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 708 RSVESLKcASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:TIGR02169 779 EALNDLE-ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 788 DLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:TIGR02169 858 NLNGKKEELEEELEELE---AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934
|
730 740 750
....*....|....*....|....*....|....*..
gi 1720363745 868 TLFKEINVYKESCVRLKELEKENKELvKRATIDIKTL 904
Cdd:TIGR02169 935 EIEDPKGEDEEIPEEELSLEDVQAEL-QRVEEEIRAL 970
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
250-1075 |
1.36e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 92.82 E-value: 1.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 250 SVELADAKAKIRRLRQELE------EKTEQLLDCKQELEQIEVELKRLQQENMNllsdaRSARMYRDELDALREKAVRVD 323
Cdd:TIGR02169 183 EENIERLDLIIDEKRQQLErlrrerEKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 324 KLESELS-RYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISELEkRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKS-------LGHEVNELtSSKLLKLEMEN 469
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDyreklekLKREINEL-KRELDRLQEEL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 470 QSLTKTVEELRStadSAAGSTSKILKVEKENQRLNKKVEILEneiiqekqslQNCQNLSKDLMKEKAQLEKTIETLREnS 549
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAKINELEEEKEDKALEIKKQE----------WKLEQLAADLSKYEQELYDLKEEYDR-V 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 550 ERQIKILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKE---------------TCGKLSKIEFEKRQMK 614
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNNVVVEDDAVA 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 615 KE-LELYKE-KGERAEELE-NELNHLGKENELLQKK-----ITNLkITCEKL----------ETLEQENSELEREnrkfk 676
Cdd:TIGR02169 561 KEaIELLKRrKAGRATFLPlNKMRDERRDLSILSEDgvigfAVDL-VEFDPKyepafkyvfgDTLVVEDIEAARR----- 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 677 kTLDSFKNLTFQLESLEKENS----------------QLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRkg 740
Cdd:TIGR02169 635 -LMGKYRMVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS-- 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 741 lELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE--ELKISSKRLEQLEKENK 818
Cdd:TIGR02169 709 -QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEAR 787
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKRat 898
Cdd:TIGR02169 788 LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE---QIKSIEKEIENLNGK-- 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 899 idiktlvtlREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddsrYKLLESKLEsTLKKSLEIKEEKIAA 978
Cdd:TIGR02169 863 ---------KEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ------LRELERKIE-ELEAQIEKKRKRLSE 921
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 979 LEARLEestNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATL 1058
Cdd:TIGR02169 922 LKAKLE---ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKL 998
|
890
....*....|....*..
gi 1720363745 1059 QAEKQALKTQLKQLETQ 1075
Cdd:TIGR02169 999 EEERKAILERIEEYEKK 1015
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1282 |
1.61e-18 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 92.73 E-value: 1.61e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 577 SAEARVKDIEKENKILHESIKEtcgkLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCE 656
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQV----LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 657 KLETLEQENSELERENRKFKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELE- 731
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEikreAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEe 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 732 ---SEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQksLEELKISSK 808
Cdd:pfam02463 405 keaQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL--LKETQLVKL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKES--CVRLKEL 886
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 887 EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLK 966
Cdd:pfam02463 563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 967 KSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGE--DDKWGRESQEATRELLKV 1044
Cdd:pfam02463 643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKkkEQREKEELKKLKLEAEEL 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1124
Cdd:pfam02463 723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1125 NAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELlhERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQ 1204
Cdd:pfam02463 803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720363745 1205 LLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQ 1282
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
505-1262 |
1.92e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 92.44 E-value: 1.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 505 KKVEILENEIIQEKQSLQNCQNLS---KDLMKEKAQLE--------KTIETLRENSERQIKILEQENEHLNQTVSSLRQR 573
Cdd:TIGR02169 187 ERLDLIIDEKRQQLERLRREREKAeryQALLKEKREYEgyellkekEALERQKEAIERQLASLEEELEKLTEEISELEKR 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 574 SQiSAEARVKDIEKENKILHE----SIKETCGKLS--------KIEFEKRQMK-------KELELYKEKGERAEELENEL 634
Cdd:TIGR02169 267 LE-EIEQLLEELNKKIKDLGEeeqlRVKEKIGELEaeiaslerSIAEKERELEdaeerlaKLEAEIDKLLAEIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 635 NHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSFKnltfqlESLEKENSQLDEENLELRRSVESLK 714
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELK---EELEDLRAELEEVDKEFAETRDELKDYR------EKLEKLKREINELKRELDRLQEELQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 715 CASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERlevsyqgldtENQRLQKALENSNKKIQQLESELQDLEMENQ 794
Cdd:TIGR02169 417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 795 TLQKSLEELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQ----LEKENKRLRQQAEIKDTTLEENNVKI 859
Cdd:TIGR02169 487 KLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERyataIEVAAGNRLNNVVVEDDAVAKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 860 GNLEKENKTLFKEINVYKES---------------CVRLKELEKENKELVK---------------RATIDIKTLVTLRE 909
Cdd:TIGR02169 567 LKRRKAGRATFLPLNKMRDErrdlsilsedgvigfAVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMVTLEG 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 910 DLV---------------------SEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDSRYKLLESKLE-STLKK 967
Cdd:TIGR02169 647 ELFeksgamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSL---QSELRRIENRLDELSQELSDASRKiGEIEK 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 968 SLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGED----------DKWGRESQEA 1037
Cdd:TIGR02169 724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsriPEIQAELSKL 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNsq 1117
Cdd:TIGR02169 804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE-- 881
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1118 stslmnqnaqlliqqsslenenesimKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKD 1197
Cdd:TIGR02169 882 --------------------------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1198 LEDRYNQLLKQKGQLEDLEKMIKT----EQEKMLLESKN------HEVVASEYKKLCGENDRLNYTYSQLLKETE 1262
Cdd:TIGR02169 936 IEDPKGEDEEIPEEELSLEDVQAElqrvEEEIRALEPVNmlaiqeYEEVLKRLDELKEKRAKLEEERKAILERIE 1010
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
605-1220 |
3.41e-18 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 91.54 E-value: 3.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 605 KIEFEKRQMKKELEL--YKEKGERAEELENELNHLGKENELLQKKITNLKitceklETLEQENSELERENRKFKKTLDSF 682
Cdd:COG1196 217 ELKEELKELEAELLLlkLRELEAELEELEAELEELEAELEELEAELAELE------AELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 683 KNLTFQLESLEKENSQLDEENLELRRsveslkcasmRMAQLQLENKELESEKEQLRKGLELMRASFKK-TERLEVSYQGL 761
Cdd:COG1196 291 YELLAELARLEQDIARLEERRRELEE----------RLEELEEELAELEEELEELEEELEELEEELEEaEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 762 DTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 842 RQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQm 921
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG- 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 922 NNDLEKLTHELEKIGLNKE---------RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQ 992
Cdd:COG1196 519 LRGLAGAVAVLIGVEAAYEaaleaalaaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 993 LRHELKTVKKNYEALKQRQDEERMVQSSIpvsgEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQL 1072
Cdd:COG1196 599 AAVDLVASDLREADARYYVLGDTLLGRTL----VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1073 ETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSL 1152
Cdd:COG1196 675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720363745 1153 YDALIKDHEKLellhERQASEYESLISKHGTLksahkNL--EVEHKDLEDRYNQLLKQKGQLE----DLEKMIK 1220
Cdd:COG1196 755 ELPEPPDLEEL----ERELERLEREIEALGPV-----NLlaIEEYEELEERYDFLSEQREDLEeareTLEEAIE 819
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
578-1073 |
4.50e-18 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 90.89 E-value: 4.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 578 AEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEK 657
Cdd:PRK03918 198 KEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 658 LETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQL 737
Cdd:PRK03918 278 LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 738 RKGLELMRASFKKTERLE--------VSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK----- 804
Cdd:PRK03918 358 EERHELYEEAKAKKEELErlkkrltgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgk 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 805 --ISSKRLEQLEKEN--KSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE--KENKTLFKEINVYKe 878
Cdd:PRK03918 438 cpVCGRELTEEHRKEllEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYN- 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 879 scvrLKELEKENKEL--VKRATIDIKTLVtlrEDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKL 956
Cdd:PRK03918 517 ----LEELEKKAEEYekLKEKLIKLKGEI---KSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEE 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 957 LESKLES------------TLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQssipVS 1024
Cdd:PRK03918 590 LEERLKElepfyneylelkDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE----LR 665
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1720363745 1025 GEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:PRK03918 666 EEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-1375 |
3.13e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 88.59 E-value: 3.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 594 ESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLgKENELLQKKITNLKitceKLETLEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREY-EGYELLKEKEALER----QKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 674 KFKKTLDSF-KNLTFQLESLEKENSQL----DEENLELRRSVESLKcASMRMAQLQLENKELESEK--EQLRKGLELMRA 746
Cdd:TIGR02169 255 KLTEEISELeKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELE-AEIASLERSIAEKERELEDaeERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 747 SFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQkslEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR---DELKDYREKLEKLKREINELKRELDR 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 827 LEKDKKQLEKENKRLRQQAEIK-------DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKE----LEKENKELVK 895
Cdd:TIGR02169 411 LQEELQRLSEELADLNAAIAGIeakinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydrVEKELSKLQR 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI-KEE 974
Cdd:TIGR02169 491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELlKRR 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 975 KIAAL------EARLEES-----------------TNYNQQLRHELK------TVKKNYEALKQRQDEERMV-------- 1017
Cdd:TIGR02169 571 KAGRAtflplnKMRDERRdlsilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVEDIEAARRLMGKYRMVtlegelfe 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1018 QSSIPVSGEDDKWGRESQEATR--ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1095
Cdd:TIGR02169 651 KSGAMTGGSRAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1096 QNTTLQTQNAKLQVEnstLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDAL-------IKDH-EKLELLH 1167
Cdd:TIGR02169 731 EEEKLKERLEELEED---LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsripeIQAElSKLEEEV 807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1168 ERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEvvaseykklcgen 1247
Cdd:TIGR02169 808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE------------- 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1248 drlnYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHL 1327
Cdd:TIGR02169 875 ----AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1720363745 1328 LD------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1375
Cdd:TIGR02169 951 LSledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1108 |
4.45e-17 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 87.87 E-value: 4.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQSmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIRR-- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 425 eslhlgweleqisRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKtVEELRSTADSAAGSTSKILKVEKENQRLN 504
Cdd:pfam15921 135 -------------RESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 505 KKvEILENEIIQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIKIL-EQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIELLlQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETCG----KLSKIEFEKRQMKKELELYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 635 NHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRSVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLlADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 714 KC--------ASMRMAQLQLENK----------ELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 776 NKKIQQLES-------ELQDLEMEN---QTLQKSLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLfkeINVYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 908 REDLVSEKL----KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLesKLESTLKKSLEIKEEKIAALEAR- 982
Cdd:pfam15921 673 SEDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM--KVAMGMQKQITAKRGQIDALQSKi 750
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 983 --LEESTNYNQQLRHELKtvkknyealkqrQDEERMVQSSIPVSGEDDKWGREsqeatRELLKVKDRLIEVERNNATLQA 1060
Cdd:pfam15921 751 qfLEEAMTNANKEKHFLK------------EEKNKLSQELSTVATEKNKMAGE-----LEVLRSQERRLKEKVANMEVAL 813
|
810 820 830 840
....*....|....*....|....*....|....*....|....*...
gi 1720363745 1061 EKQALKTQLKQLETQNNNLQAQILALQrQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:pfam15921 814 DKASLQFAECQDIIQRQEQESVRLKLQ-HTLDVKELQGPGYTSNSSMK 860
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
1.18e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 78.83 E-value: 1.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKSESQ----RVNKKVNNDASLRIHNLSILVKQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720363745 91 QETL-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1015 |
3.08e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.99 E-value: 3.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 701 EENL--------ELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLEL--MRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLlkLRELEAELEELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 851 TLEENNVKIGNLEKEnktlfkeinvYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG1196 338 ELEELEEELEEAEEE----------LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQR 1010
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEE--EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
|
....*
gi 1720363745 1011 QDEER 1015
Cdd:COG1196 486 LAEAA 490
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
266-895 |
8.09e-16 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 83.53 E-value: 8.09e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 266 ELEEKTEQLLDCKQELEQIEVELKRLQQenmNLLSDARSARMYRDELDALREKAV-----------RVDKLESELSRYKE 334
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDK---NLNKDEEKINNSNNKIKILEQQIKdlndklkknkdKINKLNSDLSKINS 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 335 RLH-DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELmeenm 413
Cdd:TIGR04523 111 EIKnDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNI----- 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 414 tlemaqKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNEL--TSSKLLK-LEMENQSLTKTVEELRSTADSAAGST 490
Cdd:TIGR04523 186 ------QKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELkkQNNQLKDnIEKKQQEINEKTTEISNTQTQLNQLK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 491 SKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Cdd:TIGR04523 260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELKSELKNQEKKLEEIQNQISQNNKIISQ 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 570 LRQRSQiSAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKgerAEELENELNHLGKENELLQKKIt 649
Cdd:TIGR04523 340 LNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ---INDLESKIQNQEKLNQQKDEQI- 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 650 nlkitceklETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKE 729
Cdd:TIGR04523 415 ---------KKLQQEKELLEKEIERLKETIIKNNS---EIKDLTNQDSVKELIIKNLDNTRESLE---TQLKVLSRSINK 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 730 LESEKEQLRKGLELMRASFKKterLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKI---- 805
Cdd:TIGR04523 480 IKQNLEQKQKELKSKEKELKK---LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelkk 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 806 ---------SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVY 876
Cdd:TIGR04523 557 enlekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636
|
650
....*....|....*....
gi 1720363745 877 KESCVRLKELEKENKELVK 895
Cdd:TIGR04523 637 KSKKNKLKQEVKQIKETIK 655
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
464-1205 |
8.23e-16 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 83.53 E-value: 8.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 464 KLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:TIGR04523 97 KINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELN 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 544 TLRenserqikileqenehlnqtvsslrqrsqisaearvKDIEKENKilhesiketcgKLSKIEFEKRQMKKELELYKEK 623
Cdd:TIGR04523 177 LLE------------------------------------KEKLNIQK-----------NIDKIKNKLLKLELLLSNLKKK 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 624 GERAEELENELNHLGKENELLQKkitnlkitcekleTLEQENSELERENRKFKKTLDSFKNLTfqlESLEKENSQLDEEN 703
Cdd:TIGR04523 210 IQKNKSLESQISELKKQNNQLKD-------------NIEKKQQEINEKTTEISNTQTQLNQLK---DEQNKIKKQLSEKQ 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 704 LELRRSVESLKCASMRMAQLQLENKELESEKEQlrkglELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:TIGR04523 274 KELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ-----DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLK 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 784 SELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTtleennvKIGNLE 863
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQ---NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE-------QIKKLQ 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 864 KENKTLFKEINvykescvRLKELEKENKELVKRATIDIKTLVTLREDLvseKLKTQQMNNDLEKLTHELEKIGLNKERll 943
Cdd:TIGR04523 419 QEKELLEKEIE-------RLKETIIKNNSEIKDLTNQDSVKELIIKNL---DNTRESLETQLKVLSRSINKIKQNLEQ-- 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 944 hdeqstddsrykllesklestLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPV 1023
Cdd:TIGR04523 487 ---------------------KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1024 SGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1103
Cdd:TIGR04523 546 ELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1104 NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALI---KDHEKLELLHERQASEYESLISK 1180
Cdd:TIGR04523 626 NEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIelmKDWLKELSLHYKKYITRMIRIKD 705
|
730 740
....*....|....*....|....*
gi 1720363745 1181 HGTLKSAHKNLEVEHKDLEDRYNQL 1205
Cdd:TIGR04523 706 LPKLEEKYKEIEKELKKLDEFSKEL 730
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
257-943 |
2.02e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.29 E-value: 2.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESELSRYKERL 336
Cdd:COG1196 171 KERKEEAERKLEATEENLERLEDILGELERQLEPLERQ-------AEKAERYR----ELKEELKELE-AELLLLKLRELE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 337 HDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:COG1196 239 AELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 417 MAQKQsmdeslhLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAgstsKILKV 496
Cdd:COG1196 316 ERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE----ELEEL 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 577 SAEARVKDIEKENKILHESIKEtcGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQ-KKITNLKITC 655
Cdd:COG1196 465 LAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGvEAAYEAALEA 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 656 EKLETLEQENSELERENRKFKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRS------VESLKCASMRMAQLQLEN 727
Cdd:COG1196 543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVLGDTL 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 728 KELESEKEQLRKGLELMRASfkkTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISS 807
Cdd:COG1196 623 LGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLFKEINVYKEscvRL 883
Cdd:COG1196 700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER---EI 776
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 884 KELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 777 EALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
325-888 |
2.45e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.03 E-value: 2.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 325 LESELSRYK--ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:PRK03918 141 LESDESREKvvRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 403 KKIEELMEENMTLEmaqkqsmdeslHLGWELEQISRTSELAEAPQKSLGHEVNELTSS--KLLKLEMENQSLTKTVEELR 480
Cdd:PRK03918 221 EELEKLEKEVKELE-----------ELKEEIEELEKELESLEGSKRKLEEKIRELEERieELKKEIEELEEKVKELKELK 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 481 STADSAAGSTSKILKVEKENQRLNKKVEILENEI--IQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Cdd:PRK03918 290 EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIngIEERiKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 558 QENEhLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYK---------------- 621
Cdd:PRK03918 370 KKEE-LERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgreltee 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 622 EKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELerenRKFKKTLDSFKNL-----TFQLESLEKEN 696
Cdd:PRK03918 449 HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL----IKLKELAEQLKELeeklkKYNLEELEKKA 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 697 SQ---LDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGL-----ELMRASFKKTERLEVSYQGLDTENQRL 768
Cdd:PRK03918 525 EEyekLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELaellkELEELGFESVEELEERLKELEPFYNEY 604
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 769 QKaLENSNKKIQQLESELQDLEMEnqtLQKSLEELKISSKRLEQLEKENKSLEQETSqlEKDKKQLEKENKRLRQQAEIK 848
Cdd:PRK03918 605 LE-LKDAEKELEREEKELKKLEEE---LDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGL 678
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1720363745 849 DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEK 888
Cdd:PRK03918 679 RAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
769-1321 |
2.66e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.03 E-value: 2.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 769 QKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqAEIK 848
Cdd:PRK03918 199 EKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELK--KEIE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 849 DttLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREdlvseklktqqMNNDLEKL 928
Cdd:PRK03918 277 E--LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE-----------KEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 929 THELEKIGLNKERLLHDEQSTDDSRYKLLE-SKLESTLK-KSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEA 1006
Cdd:PRK03918 344 KKKLKELEKRLEELEERHELYEEAKAKKEElERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1007 LKQRQDEERMVQSSIPVSG---EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqnnnlQAQI 1083
Cdd:PRK03918 424 LKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK--------ESEL 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1084 LALQRQTVSLQEQNTTLQTQNA-KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEK 1162
Cdd:PRK03918 496 IKLKELAEQLKELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1163 LELLHERQASEYESLISKHGTLKSAHKnlevehkdledRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKK 1242
Cdd:PRK03918 576 LKELEELGFESVEELEERLKELEPFYN-----------EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE 644
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 1243 LCGENDRLNYTYSqllketeilQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1321
Cdd:PRK03918 645 LRKELEELEKKYS---------EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
492-833 |
2.87e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 82.04 E-value: 2.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 492 KILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVS 568
Cdd:TIGR02169 682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKErleELEEDLSSLEQEIENVKSELK 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 569 SLRQRSQISAEARVKDIEKENKI----LHESIKETCGKLSKIEFEKRQMKKelelykekgeRAEELENELNHLGKENELL 644
Cdd:TIGR02169 762 ELEARIEELEEDLHKLEEALNDLearlSHSRIPEIQAELSKLEEEVSRIEA----------RLREIEQKLNRLTLEKEYL 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 645 QKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQ 724
Cdd:TIGR02169 832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE------ELEELEAALRDLESRLGDLKKERDELE---AQLRELE 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 725 LENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKA---LENSNKKIQQLESELQDLEMEN----QTLQ 797
Cdd:TIGR02169 903 RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDVQAELQRVEEEIRALEPVNmlaiQEYE 982
|
330 340 350
....*....|....*....|....*....|....*.
gi 1720363745 798 KSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:TIGR02169 983 EVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
606-1243 |
6.30e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.75 E-value: 6.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 606 IEFEKRQMKKELELYKEKGERAEELENELNHLgkENELLQKKITNLKitcEKLETLEQENSELERENRKFKKtldsfknl 685
Cdd:COG1196 194 ILGELERQLEPLERQAEKAERYRELKEELKEL--EAELLLLKLRELE---AELEELEAELEELEAELEELEA-------- 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 686 tfQLESLEKENSQLDEENLELRRSVEslkcasmrmaQLQLENKELESEKEQLRKGLELMRasfKKTERLEVSYQGLDTEN 765
Cdd:COG1196 261 --ELAELEAELEELRLELEELELELE----------EAQAEEYELLAELARLEQDIARLE---ERRRELEERLEELEEEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 766 QRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:COG1196 326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE---EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 846 EIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQmnndl 925
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA----- 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 926 eklthelekiglnKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEestnynqQLRHELKTVKKNYE 1005
Cdd:COG1196 478 -------------ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-------GAVAVLIGVEAAYE 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1006 ALkqrqDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKD---RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1082
Cdd:COG1196 538 AA----LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1083 ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLydALIKDHEK 1162
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE--LAERLAEE 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1163 LELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKK 1242
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
|
.
gi 1720363745 1243 L 1243
Cdd:COG1196 772 L 772
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
247-841 |
8.26e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.37 E-value: 8.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVEL--KRLQQENMNLLSDARSARmyrdeldaLREKAVRVDK 324
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELeeLRLELEELELELEEAQAE--------EYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 325 LESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:COG1196 300 LEQDIARLEERRRELE---ERLEELEEELAELEEELEELEEELEELEEE---LEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 405 IEELMEENMTLEMAQKQSMDEslhlgwELEQISRTSELAEAPQKSLghevnELTSSKLLKLEMENQSLTKTVEELRSTAD 484
Cdd:COG1196 374 LAEAEEELEELAEELLEALRA------AAELAAQLEELEEAEEALL-----ERLERLEEELEELEEALAELEEEEEEEEE 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 485 SAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNcQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:COG1196 443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQmkkelelykeKGERAEELENELNHLGKENELL 644
Cdd:COG1196 522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA----------KAGRATFLPLDKIRARAALAAA 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 645 QKKITNLkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQ 724
Cdd:COG1196 592 LARGAIG----AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 725 LENKELESEKEQLRKGLELMRASFKKTERLEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK 804
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEA-----LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742
|
570 580 590
....*....|....*....|....*....|....*..
gi 1720363745 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG1196 743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-839 |
1.07e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 80.11 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 136 QKKEEFIEKIQGLDFDTKAAVAAHIQEVTHNQENVFDLQwmEVTDMSQEDIEPLLKNMVSHLRRLIDERDEHSETIVELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI--AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 216 EERDGVhflphasssaqspcGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEN 295
Cdd:TIGR02169 350 KRRDKL--------------TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 296 MNLLSDARSARM-------YRDELDA-LREKAVRVDKLESELSRYKErlhDIEFYKARVEELKEDNQVLLETKTMLEDQL 367
Cdd:TIGR02169 416 QRLSEELADLNAaiagieaKINELEEeKEDKALEIKKQEWKLEQLAA---DLSKYEQELYDLKEEYDRVEKELSKLQREL 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 368 EGTRARSDKLH----------ELEKENLQ-----------------------LKAKLHDMEMERDMDRKK-IEELMEEN- 412
Cdd:TIGR02169 493 AEAEAQARASEervrggraveEVLKASIQgvhgtvaqlgsvgeryataievaAGNRLNNVVVEDDAVAKEaIELLKRRKa 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 413 --MTL----EMAQKQSMDESLH----LGWELEQISRTSELAEAPQKSLGHE--VNELTSSK-------LLKLE------- 466
Cdd:TIGR02169 573 grATFlplnKMRDERRDLSILSedgvIGFAVDLVEFDPKYEPAFKYVFGDTlvVEDIEAARrlmgkyrMVTLEgelfeks 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 467 --MENQSLTKTVEELRSTADSA--AGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTI 542
Cdd:TIGR02169 653 gaMTGGSRAPRGGILFSRSEPAelQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 543 ETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKETCGKLSKIEFEKRQMKK 615
Cdd:TIGR02169 733 EKLKErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEIQAELSKLEEEVSRIEA 812
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 616 elelykekgeRAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKE 695
Cdd:TIGR02169 813 ----------RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE------ELEELEAA 876
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 696 NSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKA---L 772
Cdd:TIGR02169 877 LRDLESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsL 953
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 773 ENSNKKIQQLESELQDLEMENqtlQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Cdd:TIGR02169 954 EDVQAELQRVEEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKR 1017
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
1.19e-14 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 73.21 E-value: 1.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSwfTEAwlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 94 L-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
628-1323 |
1.50e-14 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 79.29 E-value: 1.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 628 EELENELNHLGKENELLQKKITNLkitcekletleqENSELERENRKfKKTLDSFKNLTFQLESLE----KENSQLDEEN 703
Cdd:TIGR04523 36 KQLEKKLKTIKNELKNKEKELKNL------------DKNLNKDEEKI-NNSNNKIKILEQQIKDLNdklkKNKDKINKLN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 704 LELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSyqgLDTENQRLQKALENSNKKIQQLE 783
Cdd:TIGR04523 103 SDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 784 SELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Cdd:TIGR04523 180 KEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 864 KENKTLfkeinvykescvrLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKERll 943
Cdd:TIGR04523 260 DEQNKI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK-- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 944 hdeqstddsrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQrqdeermvqssipv 1023
Cdd:TIGR04523 305 --------------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSES-------------- 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1024 sgeddkwgrESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1103
Cdd:TIGR04523 357 ---------ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1104 NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGT 1183
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1184 LKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVAS------EYKKLCGENDRLNYTYSQL 1257
Cdd:TIGR04523 508 LEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEideknkEIEELKQTQKSLKKKQEEK 587
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 1258 LKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEE 1323
Cdd:TIGR04523 588 QELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
278-1108 |
3.95e-14 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 78.47 E-value: 3.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 278 KQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKavrvdKLESELSRYKERLHDIEFYKARVEELKEDNQVLL 357
Cdd:pfam02463 173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYY-----QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 358 ETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDmdrKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Cdd:pfam02463 248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELK---LLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 438 RTSELAEAPQKSLGHEVNELTSSKLLKLEMEN------QSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILE 511
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEIKREAEEEeeeeleKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 512 NEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQrsqisAEARVKDIEKENKI 591
Cdd:pfam02463 405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL-----ELKKSEDLLKETQL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 592 LHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:pfam02463 480 VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 672 NRKFKKtldSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQL-ENKELESEKEQLRKGLELMRASFKK 750
Cdd:pfam02463 560 VEERQK---LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaTLEADEDDKRAKVVEGILKDTELTK 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 751 TERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam02463 637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLK 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 831 KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-----NKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLV 905
Cdd:pfam02463 717 LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEeeksrLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL 796
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 906 TLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSryKLLESKLESTLKKSLEIKEEKIAALEARLEE 985
Cdd:pfam02463 797 KAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLL 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 986 STNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSI-PVSGEDDKWGRESQEA---------TRELLKVKDRLIEVERNN 1055
Cdd:pfam02463 875 KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNlLEEKENEIEERIKEEAeillkyeeePEELLLEEADEKEKEENN 954
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1720363745 1056 A-TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:pfam02463 955 KeEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLI 1008
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1318 |
7.69e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 77.47 E-value: 7.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETCGKLSKIEFEKRQMkkeLELYKEKGERAEELENELN 635
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 636 HLGKENELLQkkitnlkitCEKLETLEQENSELErenrKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKC 715
Cdd:pfam15921 149 NTVHELEAAK---------CLKEDMLEDSNTQIE----QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 716 ASMRMAQLQLEnKELESEKEQLR-------KGLELMRA-SFKKTERLevsyqgLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:pfam15921 216 RSLGSAISKIL-RELDTEISYLKgrifpveDQLEALKSeSQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKAS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 788 DLEMENQTLQKSLEELKISSKR-----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam15921 289 SARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 863 EKENKTLFKEIN-VYKESCVRLKEL--EKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKiglN 938
Cdd:pfam15921 369 SQESGNLDDQLQkLLADLHKREKELslEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG---Q 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 939 KERLLHDEQSTDDSRYKL--LESKLESTlKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEA-------LKQ 1009
Cdd:pfam15921 446 MERQMAAIQGKNESLEKVssLTAQLEST-KEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAtnaeitkLRS 524
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1010 RQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAE--------KQALKTQLKQLETQNNNLQa 1081
Cdd:pfam15921 525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtAGAMQVEKAQLEKEINDRR- 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1082 qiLALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHE 1161
Cdd:pfam15921 604 --LELQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1162 KLELLHERQASEYESLISK-HGTLKSAHKNLEVEHKDLEDR--------------YNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:pfam15921 678 VLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAM 757
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1227 LLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKL 1306
Cdd:pfam15921 758 TNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
|
810
....*....|...
gi 1720363745 1307 NNQCEL-LSQLKG 1318
Cdd:pfam15921 838 KLQHTLdVKELQG 850
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
255-844 |
1.96e-13 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 75.85 E-value: 1.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 255 DAKAKIRRLrqeLEEKTEQLLDCKQELEQIEvelkrlQQENMNLLSDARSARMYRDE----LDALREKAV-RVDKLESEL 329
Cdd:PRK02224 173 DARLGVERV---LSDQRGSLDQLKAQIEEKE------EKDLHERLNGLESELAELDEeierYEEQREQAReTRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 330 SRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHElEKENLQLKAKLHDMEMERDMDRkkIEELM 409
Cdd:PRK02224 244 EEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE-ERDDLLAEAGLDDADAEAVEAR--REELE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 410 EEnmtLEMAQKQSMDESLHLGWELEQISRTSELAEapqkslghevneltsskllKLEMENQSLTKTVEELRSTADSAAgs 489
Cdd:PRK02224 321 DR---DEELRDRLEECRVAAQAHNEEAESLREDAD-------------------DLEERAEELREEAAELESELEEAR-- 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 490 tSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEK-------AQLEKTIETLRENSERQIKILE----- 557
Cdd:PRK02224 377 -EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERdelrereAELEATLRTARERVEEAEALLEagkcp 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 558 ------QENEHLNQTVSSLRQRSQIsaEARVKDIEKENKILHESIkETCGKLSKIE--FEKRQMKKEL--ELYKEKGERA 627
Cdd:PRK02224 456 ecgqpvEGSPHVETIEEDRERVEEL--EAELEDLEEEVEEVEERL-ERAEDLVEAEdrIERLEERREDleELIAERRETI 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 628 EELENELNHLGKENELLQKKITnlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENlELR 707
Cdd:PRK02224 533 EEKRERAEELRERAAELEAEAE------EKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA-DAE 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 708 RSVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrASFKKtERLEvsyqGLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:PRK02224 606 DEIERLREKREALAELNDERRERLAEKRERKRELE---AEFDE-ARIE----EAREDKERAEEYLEQVEEKLDELREERD 677
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 788 DLEMENQTLQKSLEELKISSKRLEQLEKENKSLE---QETSQLEKDKKQLEKEnkrLRQQ 844
Cdd:PRK02224 678 DLQAEIGAVENELEELEELRERREALENRVEALEalyDEAEELESMYGDLRAE---LRQR 734
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
241-829 |
2.10e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD-ARSARMYRDELDALREKA 319
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAElARLEQDIARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 320 VRVDKLESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG1196 316 ERLEELEEELAELEEELEELE---EELEELEEELEEAEEELEEAEAELAEAEEA---LLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 400 MDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEEL 479
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 480 RSTADSAAGSTSKILKVEKENQRLNKKVEILEN-----EIIQEKQSLQNCQNLSK---DLMKEKAQLEKTIETLRENSER 551
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEAEADyegflEGVKAALLLAGLRGLAGavaVLIGVEAAYEAALEAALAAALQ 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 552 QikILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETcGKLSKIEFEKRQMKKELELYKEKGERAEELE 631
Cdd:COG1196 550 N--IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG-AIGAAVDLVASDLREADARYYVLGDTLLGRT 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 632 NELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKENSQLDEENLELRRSVE 711
Cdd:COG1196 627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE------AEAELEELAERLAEEELELEEALL 700
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 712 SLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKA-LENSNKKIQQLESELQDLE 790
Cdd:COG1196 701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPdLEELERELERLEREIEALG 780
|
570 580 590
....*....|....*....|....*....|....*....
gi 1720363745 791 MENQTlqkSLEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:COG1196 781 PVNLL---AIEEYEELEERYDFLSEQREDLEEARETLEE 816
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
3.59e-13 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 68.84 E-value: 3.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPayfdENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 94 L-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1097 |
4.31e-13 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 75.08 E-value: 4.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 256 AKAKIRRLRQELEEKTEQLLDCKQELEQIEVEL----KRLQQENMNLLSDARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKN---RLKEIEHNLSK 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 332 YKERLHDIEFYKARVEELKEDNQVLLETKTML----EDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Cdd:TIGR00606 264 IMKLDNEIKALKSRKKQMEKDNSELELKMEKVfqgtDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKT 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGH-EVNELTSSKLLKLEMENQSLTKTVEELRSTADS 485
Cdd:TIGR00606 344 ELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 486 AAGSTSKI--------LKVEKENQRLNKKVEILENEIIQEKQ---SLQNCQNLSKDLMKEKAQL---------------E 539
Cdd:TIGR00606 424 KQEQADEIrdekkglgRTIELKKEILEKKQEELKFVIKELQQlegSSDRILELDQELRKAERELskaeknsltetlkkeV 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 540 KTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDiEKENKILHESIKETCGKLSKIEFEKRQMKKELEL 619
Cdd:TIGR00606 504 KSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKD-EQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSK 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 620 YKEKGERAEEL----------ENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQ- 688
Cdd:TIGR00606 583 SKEINQTRDRLaklnkelaslEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGAt 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 689 ------LESLEKENS----------QLDEENLELRRSVES-LKCASMRMAQLQLENKELESEKEQLRkGLELMRASF--- 748
Cdd:TIGR00606 663 avysqfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEML-GLAPGRQSIidl 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 749 --KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ---DLEMENQTLQKSLEELKISSKRLEQLEKENKS--LE 821
Cdd:TIGR00606 742 keKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsdLD 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 822 QETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDI 901
Cdd:TIGR00606 822 RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLI 901
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 902 KTLVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAA 978
Cdd:TIGR00606 902 REIKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNT 981
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 979 LEARLEESTNYNQQLRHELKTVKKNYEALKQRqdeERMVQSSIPVSGEDDKWGRESQEATRELLKV-KDRLIEVERNNAT 1057
Cdd:TIGR00606 982 VNAQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQEHQK 1058
|
890 900 910 920
....*....|....*....|....*....|....*....|
gi 1720363745 1058 LQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1097
Cdd:TIGR00606 1059 LEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1231 |
7.26e-13 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 74.06 E-value: 7.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 262 RLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD-ARSARMYRDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEkNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 341 fykARVEELKEDNQVLL-ETKTM------LEDQLEGTRARSDKLHeLEKENLQLKAK--------LHDMEMERDMDRKKI 405
Cdd:pfam01576 82 ---SRLEEEEERSQQLQnEKKKMqqhiqdLEEQLDEEEAARQKLQ-LEKVTTEAKIKkleedillLEDQNSKLSKERKLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 406 EE--------LMEENMTLEMAQK-----QSMDESLHLGWELEQISRtSELAEAPQKSLGH--EVNELTSSKLLKLEMENQ 470
Cdd:pfam01576 158 EEriseftsnLAEEEEKAKSLSKlknkhEAMISDLEERLKKEEKGR-QELEKAKRKLEGEstDLQEQIAELQAQIAELRA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 471 SLTKTVEELRST---ADSAAGSTSKILKVEKENQRLNKKV-EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIET-- 544
Cdd:pfam01576 237 QLAKKEEELQAAlarLEEETAQKNNALKKIRELEAQISELqEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTta 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 545 ----LRENSERQI----KILEQENEHLNQTVSSLRQ-----------------RSQISAEARVKDIEKENKILHESIKET 599
Cdd:pfam01576 317 aqqeLRSKREQEVtelkKALEEETRSHEAQLQEMRQkhtqaleelteqleqakRNKANLEKAKQALESENAELQAELRTL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 600 CGKLSKIEFEKRQMKKELE-----------LYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSEL 668
Cdd:pfam01576 397 QQAKQDSEHKRKKLEGQLQelqarlseserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQEL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 669 ERENRKFKktldsfKNLTFQLESLEKENSQLDE---ENLELRRSVESlkcasmrmaQLQLENKELESEKeqlrkglelmr 745
Cdd:pfam01576 477 LQEETRQK------LNLSTRLRQLEDERNSLQEqleEEEEAKRNVER---------QLSTLQAQLSDMK----------- 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 746 asfKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:pfam01576 531 ---KKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFD 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 826 QLEKDKKQLEKENKRLRQQAEIKDTtleennvkignlEKENKTLfkeinvykeSCVRLKELEKENKELVKRATidiKTLV 905
Cdd:pfam01576 608 QMLAEEKAISARYAEERDRAEAEAR------------EKETRAL---------SLARALEEALEAKEELERTN---KQLR 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 906 TLREDLVSEKLKTQQMNNDLEK----LTHELEKIGLNKERLLHDEQSTDDSRYKL------LESKLESTLKKSLEIKEEK 975
Cdd:pfam01576 664 AEMEDLVSSKDDVGKNVHELERskraLEQQVEEMKTQLEELEDELQATEDAKLRLevnmqaLKAQFERDLQARDEQGEEK 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 976 IAALEARLEEstnYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddkwGREsqEATRELLKVKDRLIEVERNN 1055
Cdd:pfam01576 744 RRQLVKQVRE---LEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANK----GRE--EAVKQLKKLQAQMKDLQREL 814
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSL 1135
Cdd:pfam01576 815 EEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQL 894
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1136 ENENESIMKEREDLKSLYDALIKDHEKL--ELLHERQASEyesliskhgTLKSAHKNLEVEHKDLEDRYNQL-----LKQ 1208
Cdd:pfam01576 895 EEELEEEQSNTELLNDRLRKSTLQVEQLttELAAERSTSQ---------KSESARQQLERQNKELKAKLQEMegtvkSKF 965
|
1050 1060
....*....|....*....|...
gi 1720363745 1209 KGQLEDLEKMIKTEQEKMLLESK 1231
Cdd:pfam01576 966 KSSIAALEAKIAQLEEQLEQESR 988
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1148 |
2.29e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.87 E-value: 2.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 413 MTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKlEMENQSLTKTVEELRSTADSAAGSTSK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 493 ILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 570 LRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGE---RAEELENELNHLGKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 647 KITnlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCAS--------- 717
Cdd:PTZ00121 1337 KAE------EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEedkkkadel 1410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 718 MRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQtLQ 797
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AK 1489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 798 KSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKdttlEENNVKIGNLEKENKTLFKEINVYK 877
Cdd:PTZ00121 1490 KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAK----KAEEKKKADELKKAEELKKAEEKKK 1565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 878 escVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLL 957
Cdd:PTZ00121 1566 ---AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE 1642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 958 --ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQ 1035
Cdd:PTZ00121 1643 aeEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK 1722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1036 EATREllkvkdRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:PTZ00121 1723 KAEEE------NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV 1796
|
810 820 830
....*....|....*....|....*....|...
gi 1720363745 1116 SQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:PTZ00121 1797 DKKIKDIFDNFANIIEGGKEGNLVINDSKEMED 1829
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1073 |
6.60e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 6.60e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 575 QISAEARVKDIEKENKILHESIKEtcgklskIEFEKRQMKKELELYKEKGERAE-ELENELNHLGKENELLQKKITNLKI 653
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAE-------LEEELEELEEELEELEEELEEAEeELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 654 TCEKLETLEQENSELERENRKFKKTLdsfKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESE 733
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQL---EELEEAEEALLERLERLEEELEELEEALAEL-----EEEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 734 KEQLRKGLELMRASFKKTERLEVsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL 813
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEE----AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 814 EK--------------ENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENnvKIGNLEKENKTLFKEINVYKES 879
Cdd:COG1196 525 AVavligveaayeaalEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD--KIRARAALAAALARGAIGAAVD 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQqmNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRykLLES 959
Cdd:COG1196 603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL--AGRLREVTLEGEGGSAGGSLTGGSRRELLAAL--LEAE 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 960 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSsipvsgeddkwgRESQEATR 1039
Cdd:COG1196 679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL------------EELLEEEE 746
|
570 580 590
....*....|....*....|....*....|....
gi 1720363745 1040 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG1196 747 LLEEEALEELPEPPDLEELERELERLEREIEALG 780
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
7.00e-12 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 65.28 E-value: 7.00e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPswfnEAWLGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 94 L-QQLIMMPLPDILIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
376-856 |
8.62e-12 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 70.15 E-value: 8.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 376 KLHELEKENLQLKAKLHDMEMERDMDRKKIE---ELMEENMTLEMAQKQSMdeslhlgweLEQISRTSELAEAPQKSLgH 452
Cdd:pfam05557 3 ELIESKARLSQLQNEKKQMELEHKRARIELEkkaSALKRQLDRESDRNQEL---------QKRIRLLEKREAEAEEAL-R 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 453 EVNELTSSKLLKLEMENQSL---TKTVEELRSTADSAAGSTSKiLKVEKENQRLNKKVEILENEIIQEKQSLQ--NCQNL 527
Cdd:pfam05557 73 EQAELNRLKKKYLEALNKKLnekESQLADAREVISCLKNELSE-LRRQIQRAELELQSTNSELEELQERLDLLkaKASEA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 528 SkdlmKEKAQLEKTIETLRENsERQIKILEQENEhlNQTVSSLRQRSQISAEARVKDIEKENKILHESIK---ETCGKLS 604
Cdd:pfam05557 152 E----QLRQNLEKQQSSLAEA-EQRIKELEFEIQ--SQEQDSEIVKNSKSELARIPELEKELERLREHNKhlnENIENKL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 605 KIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKN 684
Cdd:pfam05557 225 LLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTS 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 685 LTFQLES----LEKENSQLDEENLELRRSVESLKCASMRMA-QLQLENKELESEKEQLR---KGLELMRASFKKTERLEV 756
Cdd:pfam05557 305 SARQLEKarreLEQELAQYLKKIEDLNKKLKRHKALVRRLQrRVLLLTKERDGYRAILEsydKELTMSNYSPQLLERIEE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 757 SYQGLdtenQRLQKALENSNKKIQQLESELQDLEMENQTLqksleELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:pfam05557 385 AEDMT----QKMQAHNEEMEAQLSVAEEELGGYKQQAQTL-----ERELQALRQQESLADPSYSKEEVDSLRRKLETLEL 455
|
490 500
....*....|....*....|
gi 1720363745 837 ENKRLRQQAEIKDTTLEENN 856
Cdd:pfam05557 456 ERQRLREQKNELEMELERRC 475
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
246-1089 |
1.48e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 69.82 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 246 RQHLSVELADAKAKIRRLRQELEEKTEQLldcKQELEQIEVELKRLQQEnmnllSDARSArmyrdELDALREkavrvdkL 325
Cdd:pfam01576 210 KRKLEGESTDLQEQIAELQAQIAELRAQL---AKKEEELQAALARLEEE-----TAQKNN-----ALKKIRE-------L 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 326 ESELSRYKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDmemerdmdrkk 404
Cdd:pfam01576 270 EAQISELQEDLESERAARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKKALEE----------- 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 405 iEELMEENMTLEMAQK--QSMDEslhLGWELEQISRTSELAEAPQKSLGHEVNEltssklLKLEMENQSLTKT-VEELRS 481
Cdd:pfam01576 339 -ETRSHEAQLQEMRQKhtQALEE---LTEQLEQAKRNKANLEKAKQALESENAE------LQAELRTLQQAKQdSEHKRK 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 482 TADSAAGS-TSKILKVEKENQRLNKKVEILENEIIQEKQSLQN----CQNLSKDLMKEKAQLEKTIETLRENSeRQIKIL 556
Cdd:pfam01576 409 KLEGQLQElQARLSESERQRAELAEKLSKLQSELESVSSLLNEaegkNIKLSKDVSSLESQLQDTQELLQEET-RQKLNL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 557 EQENEHLNQTVSSLRQRSQISAEARvKDIEKENKILHESIKETCGKLSK-------IEFEKRQMKKELELykeKGERAEE 629
Cdd:pfam01576 488 STRLRQLEDERNSLQEQLEEEEEAK-RNVERQLSTLQAQLSDMKKKLEEdagtleaLEEGKKRLQRELEA---LTQQLEE 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 630 LENELNHLGKENELLQKKITNLKItceKLETLEQENSELERENRKFKKTLDSFKNLTFQL---------ESLEKENSQLD 700
Cdd:pfam01576 564 KAAAYDKLEKTKNRLQQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALS 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 701 -----EENLELRRSVESlkcaSMRMAQLQLEN------------KELESEKEQLRKGLELMRASFKKTE----------- 752
Cdd:pfam01576 641 laralEEALEAKEELER----TNKQLRAEMEDlvsskddvgknvHELERSKRALEQQVEEMKTQLEELEdelqatedakl 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 753 RLEVSYQGLDTENQR-LQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLE--------QLEKENKSLEQE 823
Cdd:pfam01576 717 RLEVNMQALKAQFERdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEA 796
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 824 TSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVyKESCVRLKELEKE-------NKEL 893
Cdd:pfam01576 797 VKQLKKLQaqmKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGAS 875
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 894 VKRATIDIK-----TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLL---------HDEQSTDDSRYKL- 956
Cdd:pfam01576 876 GKSALQDEKrrleaRIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTsqksesarqQLERQNKELKAKLq 955
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 957 -LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHEL-KTVKKNYEALKQRQDEERMVqssipvsgedDKWGRES 1034
Cdd:pfam01576 956 eMEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHA----------DQYKDQA 1025
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1035 QEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam01576 1026 EKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
252-877 |
1.48e-11 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 70.00 E-value: 1.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSR 331
Cdd:TIGR00618 250 EAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMK 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 332 YKERLHDiefyKARVEELKEDNQVLLETKTMLEDQLE---GTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEEL 408
Cdd:TIGR00618 330 RAAHVKQ----QSSIEEQRRLLQTLHSQEIHIRDAHEvatSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 409 MEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEM-----ENQSLTKTVEELRSTA 483
Cdd:TIGR00618 406 QREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESaqslkEREQQLQTKEQIHLQE 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 484 DSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE--NSER-QIKILEQEN 560
Cdd:TIGR00618 486 TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHqlTSERkQRASLKEQM 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 561 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKK------ELELYKEKGERAEELENEL 634
Cdd:TIGR00618 566 QEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKlqpeqdLQDVRLHLQQCSQELALKL 645
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 635 NHLGKENELLQKKitnlKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEEN---LELRRSVE 711
Cdd:TIGR00618 646 TALHALQLTLTQE----RVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELEthiEEYDREFN 721
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 712 SLKCASMRM-----AQLQLENKELESEKEQLRKGL-ELMRASFKKTERLEVSYQgLDTENQRLQKALENSNKKIQQLESE 785
Cdd:TIGR00618 722 EIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHFNNNEEVTAALQ-TGAELSHLAAEIQFFNRLREEDTHL 800
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 786 LQDLEMENQTLQKSLEELKISS-----KRLEQ----LEKENKSLEQETSQLEKD---KKQLEKENKRLRQQAEIKDTTLE 853
Cdd:TIGR00618 801 LKTLEAEIGQEIPSDEDILNLQcetlvQEEEQflsrLEEKSATLGEITHQLLKYeecSKQLAQLTQEQAKIIQLSDKLNG 880
|
650 660
....*....|....*....|....
gi 1720363745 854 ENNVKIGNLEKENKTLFKEINVYK 877
Cdd:TIGR00618 881 INQIKIQFDGDALIKFLHEITLYA 904
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
628-1076 |
2.06e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 69.03 E-value: 2.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 628 EELENELNHLGKENEllQKKITNLKitceKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Cdd:COG4717 49 ERLEKEADELFKPQG--RKPELNLK----ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 708 RSVESLkcasmrmaQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKI-QQLESEL 786
Cdd:COG4717 123 KLLQLL--------PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 787 QDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEE 854
Cdd:COG4717 195 QDLAEELEELQQRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLS 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 855 NNVKIGN---------------LEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQ 919
Cdd:COG4717 271 LILTIAGvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 920 QMNNDLEKLTHELEKIGLNKER--LLHDEQSTDDSRYkllESKLEstLKKSLEIKEEKIAALEARLEESTNYNQ------ 991
Cdd:COG4717 351 ELLREAEELEEELQLEELEQEIaaLLAEAGVEDEEEL---RAALE--QAEEYQELKEELEELEEQLEELLGELEelleal 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 992 ---QLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQ 1068
Cdd:COG4717 426 deeELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEA 505
|
....*...
gi 1720363745 1069 LKQLETQN 1076
Cdd:COG4717 506 REEYREER 513
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
4.62e-11 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 67.41 E-value: 4.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 263 LRQELEEKTEQLL-------DCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 395 EMERDMDRKKIEELMEENMTLEMAQKQSmDESLHLGWELEQISRTSELAEAPQKSLghEVNEltssKLLKLEMENQSLTK 474
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQ-AELSQADALLSPSSDPGDNLAAEIMPA--EIRE----KLIRLQHENKMLRL 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 475 TVE--------ELRSTADSAAGSTSKIlkvEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLR 546
Cdd:pfam05622 297 GQEgsyrerltELQQLLEDANRRKNEL---ETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLH 373
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1720363745 547 E-NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 374 EaQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
608-1010 |
4.64e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.87 E-value: 4.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 608 FEKRQMKKELELYKEKG-------ERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKtLD 680
Cdd:COG4717 47 LLERLEKEADELFKPQGrkpelnlKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK-LL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 681 SFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRAsfKKTERLEVSYQG 760
Cdd:COG4717 126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 761 LDTENQRLQKALENSNKKIQQLESELQDLE--MENQTLQKSLEELKISSK------------------------------ 808
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLEneLEAAALEERLKEARLLLLiaaallallglggsllsliltiagvlflvl 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 809 -----RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESC--V 881
Cdd:COG4717 284 gllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeeL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 882 RLKELEKENKELVKRAtiDIKTLVTLREdLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD-DSRYKLLESK 960
Cdd:COG4717 364 QLEELEQEIAALLAEA--GVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEElEEELEELEEE 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 961 LEStLKKSLEIKEEKIAALEARLE--ESTNYNQQLRHELKTVKKNYEALKQR 1010
Cdd:COG4717 441 LEE-LEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
264-670 |
5.25e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.16 E-value: 5.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 264 RQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESELSRYKERlhdIEFYK 343
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAE---VEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 344 ARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL--EMAQKQ 421
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAE---EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneEAANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 422 SMDESLH-----LGWELEQISRTSELAEAPQKSLGHEVNELTSSkLLKLEMENQSLTKTVEELRSTADSAagstskilkv 496
Cdd:TIGR02168 824 ERLESLErriaaTERRLEDLEEQIEELSEDIESLAAEIEELEEL-IEELESELEALLNERASLEEALALL---------- 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN-SERQIKILEQENEHLNQTVSSLRQrsq 575
Cdd:TIGR02168 893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEE--- 969
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 576 isAEARVKDIEKEnkilhesIKEtcgkLSKIEFEKrqmkkeLELYKEKGERAEELENELNHLGKENELLQKKITNLKITC 655
Cdd:TIGR02168 970 --ARRRLKRLENK-------IKE----LGPVNLAA------IEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREA 1030
|
410
....*....|....*..
gi 1720363745 656 EK--LETLEQENSELER 670
Cdd:TIGR02168 1031 RErfKDTFDQVNENFQR 1047
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-676 |
5.87e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 67.84 E-value: 5.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 182 SQEDIEPLLKNMVSHLRRLIDErdeHSETIVELSEERDGvhflphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 259 KIRRLRQELEEKTEQLLDCKQELEqievelKRLQQENmnllSDARSARMYRDEL--------DALREKAVRVDKLESELS 330
Cdd:pfam15921 325 TVSQLRSELREAKRMYEDKIEELE------KQLVLAN----SELTEARTERDQFsqesgnldDQLQKLLADLHKREKELS 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 331 RYKE---RLHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL-HDMEMER 398
Cdd:pfam15921 395 LEKEqnkRLWDrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLtAQLESTK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 399 DMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELAEApqkslghEVNELTSSKLLKLEmENQSLTKTVEE 478
Cdd:pfam15921 475 EMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHLKNEGDH 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 479 LRStadsaAGSTSKILKVEKENQrlNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQIKILEQ 558
Cdd:pfam15921 543 LRN-----VQTECEALKLQMAEK--DKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQEFKILKD 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 559 ENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKekgeraeeleNELNHLG 638
Cdd:pfam15921 615 KKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------NELNSLS 673
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 1720363745 639 KENELLQKKITN----LKITCEKLE-TLEQENSELERENRKFK 676
Cdd:pfam15921 674 EDYEVLKRNFRNkseeMETTTNKLKmQLKSAQSELEQTRNTLK 716
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
6.16e-11 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 62.56 E-value: 6.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSwfDESwlSRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 94 L-QQLIMMPLPDIliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-836 |
6.82e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 67.35 E-value: 6.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESELSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSS------KLLKLEMENQSLT 473
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQisqlkkELTNSESENSEKQ 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 474 KTVEElrstadsaagSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQI 553
Cdd:TIGR04523 363 RELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKEI 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 554 KILEQENEHLNQTVSSLRqrSQISA-EARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELelyKEKGERAEELEN 632
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLT--NQDSVkELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLNE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 633 ELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSfKNLTFQLESLEKENSQLDEENLELRRSVES 712
Cdd:TIGR04523 504 EKKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQKS 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 713 LKCASmrmAQLQLENKELESEKEQLRKGLELMRASF----KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ- 787
Cdd:TIGR04523 580 LKKKQ---EEKQELIDQKEKEKKDLIKEIEEKEKKIssleKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKe 656
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 788 ------DLEMENQTLQKSLEEL---------------------KISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 657 irnkwpEIIKKIKESKTKIDDIielmkdwlkelslhykkyitrMIRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
252-1013 |
8.14e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 67.38 E-value: 8.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMyRDELDALREKAVRVDKLESELSR 331
Cdd:TIGR00606 320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAT-RLELDGFERGPFSERQIKNFHTL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 332 YKERLHDIEFYKAR-VEELKEDNQVLLETKTMLEDQLEGT-RARSDKLHELEKENLQLKAKLHDME-MERDMDR--KKIE 406
Cdd:TIGR00606 399 VIERQEDEAKTAAQlCADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRilELDQ 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 407 ELMEENMTLEMAQKQSMDESL-----HLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLL--KLEMENQSLTKTVEEL 479
Cdd:TIGR00606 479 ELRKAERELSKAEKNSLTETLkkevkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkDKMDKDEQIRKIKSRH 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 480 RSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------SERQI 553
Cdd:TIGR00606 559 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEE 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 554 KILEQENEHLNQtvsSLRQRSQISAEARVKD-IEKENKILHESIKETCGKLSKIEFEKRQMKKELE-LYKEKGERAEELE 631
Cdd:TIGR00606 639 SDLERLKEEIEK---SSKQRAMLAGATAVYSqFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQsKLRLAPDKLKSTE 715
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 632 NELNHLGKENELLqkkITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNltfqleSLEKENSQLDEENLELRrSVE 711
Cdd:TIGR00606 716 SELKKKEKRRDEM---LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN------DIEEQETLLGTIMPEEE-SAK 785
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 712 SLKCASMRMAQLQLENKELESEKEQL---RKGLELMRASF---KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESE 785
Cdd:TIGR00606 786 VCLTDVTIMERFQMELKDVERKIAQQaakLQGSDLDRTVQqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSK 865
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 786 LQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:TIGR00606 866 TNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 866 NKTLFKEINVYkescvrLKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLnKERLLH 944
Cdd:TIGR00606 946 IKEKVKNIHGY------MKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI-QERWLQ 1018
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 945 DEQSTDDSRYKLLEskLESTLKKSLEikeekiAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDE 1013
Cdd:TIGR00606 1019 DNLTLRKRENELKE--VEEELKQHLK------EMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-669 |
8.15e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 67.37 E-value: 8.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 201 IDERDEHSETIVELSEERDGVhflphasssaqspcgspGMKRTESRQHLSVELADAKAkIRRLRQELEEKTEQlldCKQE 280
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEA-VEARREELEDRDEE---LRDR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 281 LEQIEVELKRLQQENMNLLSDARSArmyRDELDALREKAvrvDKLESELSRYKErlhDIEFYKARVEELKEDNQVLLETK 360
Cdd:PRK02224 330 LEECRVAAQAHNEEAESLREDADDL---EERAEELREEA---AELESELEEARE---AVEDRREEIEELEEEIEELRERF 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 361 TMLEDQLEGTRARSDKLHElekenlqLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK-----QSMDESLHLGWELEQ 435
Cdd:PRK02224 401 GDAPVDLGNAEDFLEELRE-------ERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETIEED 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 436 ISRTSELaEAPQKSLGHEVNEL-----TSSKLLKLEMENQSL---TKTVEELRSTA-DSAAGSTSKILKVEKENQRLNKK 506
Cdd:PRK02224 474 RERVEEL-EAELEDLEEEVEEVeerleRAEDLVEAEDRIERLeerREDLEELIAERrETIEEKRERAEELRERAAELEAE 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 507 VEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIleqenEHLNQTVSSLRQRSQISAEarVKDIE 586
Cdd:PRK02224 553 AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAI-----ADAEDEIERLREKREALAE--LNDER 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 587 KEN-KILHESIKETCGKLSKIEFEK-RQMKKELELYKEK-GERAEELENELNHL-----GKENEL-----LQKKITNLKI 653
Cdd:PRK02224 626 RERlAEKRERKRELEAEFDEARIEEaREDKERAEEYLEQvEEKLDELREERDDLqaeigAVENELeeleeLRERREALEN 705
|
490
....*....|....*.
gi 1720363745 654 TCEKLETLEQENSELE 669
Cdd:PRK02224 706 RVEALEALYDEAEELE 721
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1377 |
8.46e-11 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 67.77 E-value: 8.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESELSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELAEAPQKSLGHEVNELTSSK-----------LLKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKEKdelnkykskisEIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 467 MENQSLTKTV--EELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETCGKLSKIefeKRQMKKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 618 ELYKEKGERAEELENELnhlgkENELLQKKITNLKITCE-KLETLEQENSELERENRKFKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 695 ENSQLDEENLELRRSVESLKCA---SMRMAQLQLEN---KELESEKEQLRKGLELMRASFKKTERLEVSYQGLD------ 762
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDfgkeen 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 763 ----TENQRLQKALENSNKKIQQLESELQDLEM-------ENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR01612 1107 ikyaDEINKIKDDIKNLDQKIDHHIKALEEIKKksenyidEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKK 1186
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 832 KQLEKENKRLRQQAEIK--DTTLEE-NNVKIGNLEKENKTLFKEIN-VYKESCVRLKELEKENKEL--VKRATIDIKTLV 905
Cdd:TIGR01612 1187 NIYDEIKKLLNEIAEIEkdKTSLEEvKGINLSYGKNLGKLFLEKIDeEKKKSEHMIKAMEAYIEDLdeIKEKSPEIENEM 1266
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 906 TLREDLVSEkLKTQQMNNDLEKLTHELEKiglnkerllHDEQSTDDSRYKLLESKLESTLKKSL-EIKEEkiaaLEARLE 984
Cdd:TIGR01612 1267 GIEMDIKAE-METFNISHDDDKDHHIISK---------KHDENISDIREKSLKIIEDFSEESDInDIKKE----LQKNLL 1332
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 985 ESTNYNQQLRHELKTVKKNYEALKQRQdeermVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQA 1064
Cdd:TIGR01612 1333 DAQKHNSDINLYLNEIANIYNILKLNK-----IKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSK 1407
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1065 LKTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE---N 1139
Cdd:TIGR01612 1408 IES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATNDhdfN 1484
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1140 ESIMKERED----LKSLYDALIKDHEKLELLHERQASEYESLISKHGTLK------SAHKNLEVEHKDLEDRYNQLLKQK 1209
Cdd:TIGR01612 1485 INELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKFILEA 1564
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1210 GQLEDLEKMIKTEQEKMLLESKNHEvvaSEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLN-NSKLEQTRLEAE 1288
Cdd:TIGR01612 1565 EKSEQKIKEIKKEKFRIEDDAAKND---KSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESiEKKISSFSIDSQ 1641
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1289 FSKLKEQYQQLDITSTKLnnqcELLSQLKGNLEEENRHlLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLN--EL 1366
Cdd:TIGR01612 1642 DTELKENGDNLNSLQEFL----ESLKDQKKNIEDKKKE-LDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANkeEI 1716
|
1210
....*....|.
gi 1720363745 1367 RRQKEKLEEKI 1377
Cdd:TIGR01612 1717 ESIKELIEPTI 1727
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
346-878 |
1.33e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 66.46 E-value: 1.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 346 VEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEnMTLEMAQKQSMDE 425
Cdd:PRK01156 161 INSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIE-YNNAMDDYNNLKS 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 426 SLH-LGWELEQISR-TSELAEAPQK--SLGHEVNELTSSKLLKLEMENQSLTKTVEELRS--TADSAAGSTSKILK-VEK 498
Cdd:PRK01156 240 ALNeLSSLEDMKNRyESEIKTAESDlsMELEKNNYYKELEERHMKIINDPVYKNRNYINDyfKYKNDIENKKQILSnIDA 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 499 ENQRLN---KKVEILE---NEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrENSERQIKILEQENEHLNQTVSSLRQ 572
Cdd:PRK01156 320 EINKYHaiiKKLSVLQkdyNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 573 RSQISAEARVKDIEKENKilheSIKETCGKLSKIEFEKRQMKKELE-----------------------------LYKEK 623
Cdd:PRK01156 399 IQEIDPDAIKKELNEINV----KLQDISSKVSSLNQRIRALRENLDelsrnmemlngqsvcpvcgttlgeeksnhIINHY 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 624 GERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSE--------LERENRKFKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK01156 475 NEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSIneynkiesARADLEDIKIKINELKDKHDKYEEIKNR 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 696 NSQLDEENLELRRSvESLKCASMRmAQLQLENkeLESEKEQLRKGLELMRasfKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:PRK01156 555 YKSLKLEDLDSKRT-SWLNALAVI-SLIDIET--NRSRSNEIKKQLNDLE---SRLQEIEIGFPDDKSYIDKSIREIENE 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 776 NKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE-------NKRLRQQAEIK 848
Cdd:PRK01156 628 ANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKAlddakanRARLESTIEIL 707
|
570 580 590
....*....|....*....|....*....|...
gi 1720363745 849 DTTLEENNVKIGNLEKE---NKTLFKEINVYKE 878
Cdd:PRK01156 708 RTRINELSDRINDINETlesMKKIKKAIGDLKR 740
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-838 |
1.88e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 1.88e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 203 ERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 280 ELEQIEVELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESELSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 435 QISRTSELAEAPQKSlghevneltSSKLLKLEMENqsltKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEI 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 515 IQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIkileqENEHLNQTVSSLRQRSQISAEARVKdiEKENKILHE 594
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAE 1623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 595 SIKetcgklsKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRK 674
Cdd:PTZ00121 1624 ELK-------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 675 FKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR--KGLELMRASFKKTE 752
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAhlKKEEEKKAEEIRKE 1776
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRlEQLEKENKSLEqETSQLEKDKK 832
Cdd:PTZ00121 1777 KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK-EVADSKNMQLE-EADAFEKHKF 1854
|
....*.
gi 1720363745 833 QLEKEN 838
Cdd:PTZ00121 1855 NKNNEN 1860
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
688-1218 |
4.87e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 64.68 E-value: 4.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 688 QLESLEKENSQLDEEnlELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrasfKKTERLEvSYQGLDTENQR 767
Cdd:PRK02224 185 QRGSLDQLKAQIEEK--EEKDLHERLNGLESELAELDEEIERYEEQREQARETRD------EADEVLE-EHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 768 LQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL------------------KISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELeeerddllaeaglddadaEAVEARREELEDRDEELRDRLEECRV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKR---ATIDIKTLVT 906
Cdd:PRK02224 336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE---EIEELEEEIEELRERfgdAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD------EQSTDDS-RYKLLESKLE--STLKKSLEIKEEKIA 977
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecGQPVEGSpHVETIEEDRErvEELEAELEDLEEEVE 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 978 ALEARLEESTNYnQQLRHELKTVKKNYEALKQRQDEER--------MVQSSIPVSGEDDKWGRESQEATRELlkvKDRLI 1049
Cdd:PRK02224 493 EVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRetieekreRAEELRERAAELEAEAEEKREAAAEA---EEEAE 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1050 EVERNNATLQAEKQALKTQLKQLETQnNNLQAQILALQRQTVSLQEQNTTLQTQNAKlqvENSTLNSQSTSlmnqnaqll 1129
Cdd:PRK02224 569 EAREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDE---RRERLAEKRER--------- 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1130 IQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQaseyESLISKHGTLKSAHKNLEV---EHKDLEDRYNQLL 1206
Cdd:PRK02224 636 KRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREER----DDLQAEIGAVENELEELEElreRREALENRVEALE 711
|
570
....*....|..
gi 1720363745 1207 KQKGQLEDLEKM 1218
Cdd:PRK02224 712 ALYDEAEELESM 723
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
770-1378 |
5.73e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 64.70 E-value: 5.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqaeikd 849
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPEL---REELEKLEKEVKELEELKEEIEELEKELESLEGSKR------- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 850 tTLEEnnvKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKratidiktLVTLREDLVSEKlktqqmnNDLEKLT 929
Cdd:PRK03918 256 -KLEE---KIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK--------LSEFYEEYLDEL-------REIEKRL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 930 HELEKIGLNKERLLHDEQStddsryklLESKLESTLKKSLEIKEEKiaaleARLEEStnynQQLRHELKTVKKNYEALKQ 1009
Cdd:PRK03918 317 SRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL-----EELEER----HELYEEAKAKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1010 RqdeermvqssipvsgeddKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA--QILALQ 1087
Cdd:PRK03918 380 R------------------LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakGKCPVC 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1088 RQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENEnesIMKERE--DLKSLYDALIKDHEKLEL 1165
Cdd:PRK03918 442 GRELTEEHRKELLEEYTAEL----KRIEKELKEIEEKERKLRKELRELEKV---LKKESEliKLKELAEQLKELEEKLKK 514
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1166 LH----ERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKmikteqEKMLLESKNHEVVASEYK 1241
Cdd:PRK03918 515 YNleelEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEE------ELAELLKELEELGFESVE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1242 KLCGENDRLNYTYSQLLKeteilqmdhknLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1321
Cdd:PRK03918 589 ELEERLKELEPFYNEYLE-----------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 1322 EEN----RHLLDQIQTLMLQNRTLLEQNMESKDlfhveqrQYIDKLNELRRQKEKLEEKIM 1378
Cdd:PRK03918 658 EEEyeelREEYLELSRELAGLRAELEELEKRRE-------EIKKTLEKLKEELEEREKAKK 711
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
241-570 |
8.43e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 8.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 241 KRTESRQH---LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllsdarsarmYRDELDALRE 317
Cdd:TIGR02169 696 ELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 318 kavRVDKLESELSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL 391
Cdd:TIGR02169 766 ---RIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQR 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQS 471
Cdd:TIGR02169 843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 472 LTK---------TVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILE---NEIIQEKQSLQNCQNLSKD----LMKEK 535
Cdd:TIGR02169 923 KAKlealeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEER 1002
|
330 340 350
....*....|....*....|....*....|....*..
gi 1720363745 536 AQLEKTIETLrENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1003 KAILERIEEY-EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-750 |
8.91e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 63.63 E-value: 8.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 259 KIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESELSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 419 QKQSMDESLHLGWELEQISRTSELAeapqkslghevneLTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILkvek 498
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLL-------------LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLF---- 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 499 enqRLNKKVEILENEIIQEKQSLQNCQNLskdlmkEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:COG4717 291 ---LLLAREKASLGKEAEELQALPALEEL------EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 579 EARVKDIEKENKILHESIKETcgklSKIEFEKRQmkKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITcEKL 658
Cdd:COG4717 362 ELQLEELEQEIAALLAEAGVE----DEEELRAAL--EQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELE-EEL 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 659 ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEK-ENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQL 737
Cdd:COG4717 435 EELEEELEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
490
....*....|...
gi 1720363745 738 RKGLELMRASFKK 750
Cdd:COG4717 515 PPVLERASEYFSR 527
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1036-1371 |
1.04e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.80 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1036 EATRE-LLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:COG1196 182 EATEEnLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-----AELLLLKLRELEAELEELEAELEELEAELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1109 VENSTLNsqstslmNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYEsliskhgTLKSAH 1188
Cdd:COG1196 257 ELEAELA-------ELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE-------RLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1189 KNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDH 1268
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1269 KNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmLQNRTLLEQNMES 1348
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAE 481
|
330 340
....*....|....*....|...
gi 1720363745 1349 KDLFHVEQRQYIDKLNELRRQKE 1371
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYE 504
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
305-1031 |
1.25e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 63.45 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 305 ARMYRDELDALREKAVRVDKLESELSRYKERLHD-----IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Cdd:TIGR00618 182 ALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDtyherKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 380 L-----EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGweleqiSRTSELAEAPQKSLGHEV 454
Cdd:TIGR00618 262 LkqlraRIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQ------SKMRSRAKLLMKRAAHVK 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 455 NELTSSKLLKLEmenQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEiiqeKQSLQNCQNLSKDLMKE 534
Cdd:TIGR00618 336 QQSSIEEQRRLL---QTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTL----TQKLQSLCKELDILQRE 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 535 KAQLEktIETLRENSERQIKILEQENEHLNQTVSSLRQrsqISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMK 614
Cdd:TIGR00618 409 QATID--TRTSAFRDLQGQLAHAKKQQELQQRYAELCA---AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 615 KELELYKEKGERAEEL-ENELNHLGKENELLQKK--ITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNltfQLES 691
Cdd:TIGR00618 484 QETRKKAVVLARLLELqEEPCPLCGSCIHPNPARqdIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERK---QRAS 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 692 LEKENSQLDEENLELRRSVESLKCASMRMAQL-QLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:TIGR00618 561 LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNItVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKisskrLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQaeikDT 850
Cdd:TIGR00618 641 LALKLTALHALQLTLTQERVREHALSIRVLPKEL-----LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREL----ET 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 851 TLEENNVKIGNLEKENKTLFKEINVykescvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:TIGR00618 712 HIEEYDREFNEIENASSSLGSDLAA------REDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAA 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 931 ELEkiglNKERLLhdeqSTDDSRYKLLESKLESTLKKSLEIKE---EKIAALEARLEESTNYNQQLRHELKTVKKNYEAL 1007
Cdd:TIGR00618 786 EIQ----FFNRLR----EEDTHLLKTLEAEIGQEIPSDEDILNlqcETLVQEEEQFLSRLEEKSATLGEITHQLLKYEEC 857
|
730 740
....*....|....*....|....
gi 1720363745 1008 KQRQDEerMVQSSIPVSGEDDKWG 1031
Cdd:TIGR00618 858 SKQLAQ--LTQEQAKIIQLSDKLN 879
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
456-877 |
1.57e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.86 E-value: 1.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 456 ELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEK--QSLQNCQNLSKDLMK 533
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 534 EKAQLEKTIETLRENsERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQM 613
Cdd:COG4717 147 RLEELEERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 614 KKELELYKEKGERAEELENE-------------LNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLD 680
Cdd:COG4717 226 EEELEQLENELEAAALEERLkearlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 681 SFKNLTfQLESLEKE--NSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR-KGLELMRASF--KKTERLE 755
Cdd:COG4717 306 ELQALP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQlEELEQEIAALlaEAGVEDE 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 756 VSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKslEELKissKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:COG4717 385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELE---EELEELEEELEELEEELEELREELAELE 459
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1720363745 836 KENKRLRqqaeiKDTTLEENNVKIGNLEKENKTLFKEINVYK 877
Cdd:COG4717 460 AELEQLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
605-1241 |
1.74e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 62.82 E-value: 1.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 605 KIEFEKRQMKKELELYKEK-GERAEELENELNHLGKENELLQKKITNLKITC----EKLETLEQENSELERE----NRKF 675
Cdd:pfam05483 113 KIIEAQRKAIQELQFENEKvSLKLEEEIQENKDLIKENNATRHLCNLLKETCarsaEKTKKYEYEREETRQVymdlNNNI 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 676 KKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELES-EKEQLRKGLE-LMRASFKKTER 753
Cdd:pfam05483 193 EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQItEKENKMKDLTfLLEESRDKANQ 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 754 LEvsyqgldtENQRLQ-KALENSNKKIQQLESELQDLEMENQ---TLQKSLEE-LKISSKRLEQLEKENKSLEQETSQLE 828
Cdd:pfam05483 273 LE--------EKTKLQdENLKELIEKKDHLTKELEDIKMSLQrsmSTQKALEEdLQIATKTICQLTEEKEAQMEELNKAK 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 829 KDKKQLEKENKRLRQQAEikdTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELeKENKELVKRatiDIKTLVTLR 908
Cdd:pfam05483 345 AAHSFVVTEFEATTCSLE---ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF-KNNKEVELE---ELKKILAED 417
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 909 EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD--EQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES 986
Cdd:pfam05483 418 EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDleIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 987 TNYNQQLRHE-----LKTVKKNYEALKQRQDEERMVQSsIPVSGEDDKWGRESQEATRELLK-----VKDRLIEVERNNA 1056
Cdd:pfam05483 498 LLENKELTQEasdmtLELKKHQEDIINCKKQEERMLKQ-IENLEEKEMNLRDELESVREEFIqkgdeVKCKLDKSEENAR 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1057 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ----TQNAKLQVENSTLNSQSTSL---------MN 1123
Cdd:pfam05483 577 SIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsAENKQLNAYEIKVNKLELELasakqkfeeII 656
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1124 QNAQLLIQQSSLENENesIMKEREDLKSLYDALIKDHEKLEL-----------LHERQASEYESLISKHGTLKSAHKNLE 1192
Cdd:pfam05483 657 DNYQKEIEDKKISEEK--LLEEVEKAKAIADEAVKLQKEIDKrcqhkiaemvaLMEKHKHQYDKIIEERDSELGLYKNKE 734
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 1193 VEHK--------DLEDRYNQLLKQKGQLEdlekMIKTEQEKMLLESKNHEVVASEYK 1241
Cdd:pfam05483 735 QEQSsakaaleiELSNIKAELLSLKKQLE----IEKEEKEKLKMEAKENTAILKDKK 787
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
614-1229 |
1.96e-09 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 63.17 E-value: 1.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 614 KKELELYKEKGERaEELENELNHlgKENELLQKKITNLK-----ITCEKLETLEQENSELERENRKFKKTLDSFKNLTfq 688
Cdd:COG5022 821 KLQKTIKREKKLR-ETEEVEFSL--KAEVLIQKFGRSLKakkrfSLLKKETIYLQSAQRVELAERQLQELKIDVKSIS-- 895
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 689 leSLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESEKEQLRKGlELMRASFKKTERLEVSyQGLDTENQRL 768
Cdd:COG5022 896 --SLKLVNLELESEIIELKKSLSSD-----LIENLEFKTELIARLKKLLNNI-DLEEGPSIEYVKLPEL-NKLHEVESKL 966
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 769 QKA---LENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:COG5022 967 KETseeYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILK 1046
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 846 EIKD----TTLEEN----NVKIGNLEKENKTLFK------EINVYKESCVRLKELEKENKELVKratiDIKTLVTLREDL 911
Cdd:COG5022 1047 PLQKlkglLLLENNqlqaRYKALKLRRENSLLDDkqlyqlESTENLLKTINVKDLEVTNRNLVK----PANVLQFIVAQM 1122
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 912 VSEKLKtQQMNNDLEKLTHELEKI--GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEekiAALEARLEESTNY 989
Cdd:COG5022 1123 IKLNLL-QEISKFLSQLVNTLEPVfqKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQS---ALYDEKSKLSSSE 1198
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 990 NQQLRHELKTVKKNYEALKQRQDEERMVQS--------SIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAE 1061
Cdd:COG5022 1199 VNDLKNELIALFSKIFSGWPRGDKLKKLISegwvpteySTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLE 1278
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1062 KQALKTQLKQLETQNNNLQAQILALQRQTVSLQ-----EQNTTLQtQNAKLQVENSTLNSQSTSLMnqNAQLLIQqssLE 1136
Cdd:COG5022 1279 EEVLPATINSLLQYINVGLFNALRTKASSLRWKsatevNYNSEEL-DDWCREFEISDVDEELEELI--QAVKVLQ---LL 1352
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1137 NENESIMKEREDL-KSLYDALIKdheklELLHERQASEYEsliskHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQlEDL 1215
Cdd:COG5022 1353 KDDLNKLDELLDAcYSLNPAEIQ-----NLKSRYDPADKE-----NNLPKEILKKIEALLIKQELQLSLEGKDETE-VHL 1421
|
650
....*....|....
gi 1720363745 1216 EKMIKTEQEKMLLE 1229
Cdd:COG5022 1422 SEIFSEEKSLISLD 1435
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
434-1016 |
2.59e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 62.43 E-value: 2.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 434 EQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQ--SLTKTVEELRSTADSAAGSTskilKVEKEN-QRLNKKVEIL 510
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKmkDLTFLLEESRDKANQLEEKT----KLQDENlKELIEKKDHL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 511 ENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLrqrsqisaEARVKDIEKENK 590
Cdd:pfam05483 295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF--------EATTCSLEELLR 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 591 ILHESIKETCGKLSKIEFEKRQMKKELE-LYKEKGERAEELENELNHLGKENELLQKKITNLKITcEKLETLEQENSELE 669
Cdd:pfam05483 367 TEQQRLEKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIA-EELKGKEQELIFLL 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 670 RENRKfkktldSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMA----QLQLENKELESEKEQLRKGLELMR 745
Cdd:pfam05483 446 QAREK------EIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTahcdKLLLENKELTQEASDMTLELKKHQ 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 746 ASFKKTERLEvsyqgldtenQRLQKALENSNKKIQQLESELQDLEMEnqtLQKSLEELKIsskRLEQLEKENKSLEQETS 825
Cdd:pfam05483 520 EDIINCKKQE----------ERMLKQIENLEEKEMNLRDELESVREE---FIQKGDEVKC---KLDKSEENARSIEYEVL 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLkELEKEN-----KELVKRATID 900
Cdd:pfam05483 584 KKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL-ELELASakqkfEEIIDNYQKE 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 901 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLkKSLEIKEEKIAALE 980
Cdd:pfam05483 663 IEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL-GLYKNKEQEQSSAK 741
|
570 580 590
....*....|....*....|....*....|....*.
gi 1720363745 981 ARLEESTNynqQLRHELKTVKKNYEALKQRQDEERM 1016
Cdd:pfam05483 742 AALEIELS---NIKAELLSLKKQLEIEKEEKEKLKM 774
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
521-873 |
5.51e-09 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 60.68 E-value: 5.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE--KENKILHESIKE 598
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEkyKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 599 TCGKLSKIEFEKRQMKKELEL-YKEKGERAEELENELNHLGKEnellQKKITNLKitcekletlEQENSELERENRKFKK 677
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------KEEEAERKQLQAKLQQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVS 757
Cdd:pfam07888 183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 758 YQGLDTENQRLQKALENSNKKIQQLESELQDLEM-----------ENQTLQKSLEELKISSKRL-EQLEKENKSLEQETS 825
Cdd:pfam07888 260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLsAELQRLEERLQEERM 339
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1720363745 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:pfam07888 340 EREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1026-1295 |
1.09e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1026 EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNT 1098
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1099 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLI 1178
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1179 SKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLED----LEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTY 1254
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEalaeLEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1720363745 1255 SQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQ 1295
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
666-1181 |
1.87e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.40 E-value: 1.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 666 SELERENRK-FKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELm 744
Cdd:COG4717 49 ERLEKEADElFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 745 RASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISS-KRLEQLEKENKSLEQE 823
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEennvkignLEKENKTLFKEINVYKESCVRLkELEKENKELVKRATIDIKT 903
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELE--------AAALEERLKEARLLLLIAAALL-ALLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnkerllhdeqstdDSRYKLLESKLESTLKK---SLEIKEEKIAALE 980
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGKEAEELQAL---------------PALEELEEEELEELLAAlglPPDLSPEELLELL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 981 ARLEESTNYNQQLRHELKTVKknyeaLKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQA 1060
Cdd:COG4717 344 DRIEELQELLREAEELEEELQ-----LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1061 EKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTlnsqstslmnqnAQLLIQQSSLENENE 1140
Cdd:COG4717 419 EELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGEL------------AELLQELEELKAELR 486
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 1720363745 1141 SIMKEREDLKSLYDALikdHEKLELLHERQASEYESLISKH 1181
Cdd:COG4717 487 ELAEEWAALKLALELL---EEAREEYREERLPPVLERASEY 524
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
257-664 |
2.41e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 59.31 E-value: 2.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSarmyrdeldALREKAVRVDKLESELSRYKERL 336
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE----LSDASR---------KIGEIEKEIEQLEQEEEKLKERL 739
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 337 HDIEfykarvEELKEDNQVLLETKTMLEDqLEGtrarsdKLHELEKENLQLKAKLHDmeMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR02169 740 EELE------EDLSSLEQEIENVKSELKE-LEA------RIEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLE 804
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 417 maqkqsmdeslhlgwelEQISRTSELAEAPQKSLGhevneltsskllKLEMENQSLTKTVEELRSTADSAagsTSKILKV 496
Cdd:TIGR02169 805 -----------------EEVSRIEARLREIEQKLN------------RLTLEKEYLEKEIQELQEQRIDL---KEQIKSI 852
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 497 EKENQRLNKKVEILENEiiqekqsLQNCQNLSKDLMKEKAQLEKTIETLR---ENSERQIKILEQENEHLNQTVSSLRQR 573
Cdd:TIGR02169 853 EKEIENLNGKKEELEEE-------LEELEAALRDLESRLGDLKKERDELEaqlRELERKIEELEAQIEKKRKRLSELKAK 925
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 574 SQIsAEARVKDIEKENKILhESIKETCGKLSKIEFEKRQMKKELELYKEKGERA----EELENELNHLGKENELLQKKIT 649
Cdd:TIGR02169 926 LEA-LEEELSEIEDPKGED-EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyEEVLKRLDELKEKRAKLEEERK 1003
|
410
....*....|....*
gi 1720363745 650 NLKITCEKLETLEQE 664
Cdd:TIGR02169 1004 AILERIEEYEKKKRE 1018
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1257 |
2.52e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 59.14 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 725 LENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeikdttlEENNVKIGNLEKENKTLFKEINVYKESCVRLK 884
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELE-------ERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 885 ELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR--YKLLESKLE 962
Cdd:PRK01156 312 QILSNIDAEINKYHAIIKKLSVLQKDY-NDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIeeYSKNIERMS 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMV------QSSIPVSGE---DDKWGRE 1033
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNmemlngQSVCPVCGTtlgEEKSNHI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1034 SQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN-----------LQAQILALQRQTVSLQEQNTTL-Q 1101
Cdd:PRK01156 471 INHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINksineynkiesARADLEDIKIKINELKDKHDKYeE 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1102 TQNAKLQVENSTLNSQSTSLMNQNAQLliqqSSLENENesIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKh 1181
Cdd:PRK01156 551 IKNRYKSLKLEDLDSKRTSWLNALAVI----SLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIRE- 623
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 1182 gtlksahknLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQL 1257
Cdd:PRK01156 624 ---------IENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKAL 690
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
359-846 |
2.57e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.01 E-value: 2.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 359 TKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISR 438
Cdd:COG4717 65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ-----ELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 439 tsELAEAPQK--SLGHEVNELTSskllkLEMENQSLTKTVEELRSTADSAAGSTSkiLKVEKENQRLNKKVEILENEIIQ 516
Cdd:COG4717 140 --ELAELPERleELEERLEELRE-----LEEELEELEAELAELQEELEELLEQLS--LATEEELQDLAEELEELQQRLAE 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETlrenserqikilEQENEHLNQTVSSLRQRSQISA-EARVKDIEKENKILHES 595
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEA------------AALEERLKEARLLLLIAAALLAlLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 596 IKETCGKLSKIEFEKRQMKKELE--------LYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSE 667
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGkeaeelqaLPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 668 LEREnrkfkktldsfknltFQLESLEKENSQLDEENLElrRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRAS 747
Cdd:COG4717 359 LEEE---------------LQLEELEQEIAALLAEAGV--EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 748 FKKT--ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEmENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:COG4717 422 LEALdeEELEEELEELEEELEELEEELEELREELAELEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALE 500
|
490 500
....*....|....*....|..
gi 1720363745 826 QLEKDKKQLEKENK-RLRQQAE 846
Cdd:COG4717 501 LLEEAREEYREERLpPVLERAS 522
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1202 |
3.05e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 3.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 848 KDT---TLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 925 LEKLTHELEKIgLNKERLLHDEQSTDDSRYKLL-----------ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQL 993
Cdd:COG4717 222 LEELEEELEQL-ENELEAAALEERLKEARLLLLiaaallallglGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 994 RHELKTVKKNY--EALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRelLKVKDRLIEVERNNATLQAEKQALKTQLKQ 1071
Cdd:COG4717 301 GKEAEELQALPalEELEEEELEELLAALGLPPDLSPEELLELLDRIEE--LQELLREAEELEEELQLEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1072 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDL 1149
Cdd:COG4717 379 AGVEDEEELRAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAEL 458
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1150 KSLYDALIKDHEKLELLHERQ--ASEYESLISKHGTLKSAHKNLEVEHKDLEDRY 1202
Cdd:COG4717 459 EAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
252-1348 |
6.10e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 58.14 E-value: 6.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKrlqqENMNLLSDARSARMYRDELDALREK----AVRVDK--- 324
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIK----AQINDLEDVADKAISNDDPEEIEKKieniVTKIDKkkn 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 325 LESELSRYKERLHDIEFYKARVEELKEDNQVLLET--KTMLEDQLEGTRARSDKLHELEK-----ENLQLKAKLHDMEME 397
Cdd:TIGR01612 1188 IYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNlgKLFLEKIDEEKKKSEHMIKAMEAyiedlDEIKEKSPEIENEMG 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 398 RDMDRKKIEELM-------EENMTLEMAQKQSM----DESLHLGWELEQISRTSELAEAPQKSL------GHEVNE---- 456
Cdd:TIGR01612 1268 IEMDIKAEMETFnishdddKDHHIISKKHDENIsdirEKSLKIIEDFSEESDINDIKKELQKNLldaqkhNSDINLylne 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 457 -------LTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQE--KQSLQNCQNL 527
Cdd:TIGR01612 1348 ianiyniLKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKdiDECIKKIKEL 1427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETCGKLSKIE 607
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDEAD 1503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 608 FEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKtldsFKNLTF 687
Cdd:TIGR01612 1504 KNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKEKF 1579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 688 QLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTErLEVSYQGLDTEnQR 767
Cdd:TIGR01612 1580 RIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISSFSIDSQDTE-LKENGDNLNSL-QE 1657
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 768 LQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKiSSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:TIGR01612 1658 FLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHK-KNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNT 1736
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 848 KD-------TTLEENNVKIGNLEKENKTLFKEINVYKESCVR-------------------LKELEKENKELVKRATIDI 901
Cdd:TIGR01612 1737 NDlegidpnEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKepitydeikntrinaqnefLKIIEIEKKSKSYLDDIEA 1816
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 902 KTLvtlreDLVSEKLKtQQMNNDLEKLTHELEKI---------GLNKERLLHDEQSTDDSRYKLLESKLESTLKK--SLE 970
Cdd:TIGR01612 1817 KEF-----DRIINHFK-KKLDHVNDKFTKEYSKInegfddiskSIENVKNSTDENLLFDILNKTKDAYAGIIGKKyySYK 1890
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 971 IKEEKIAALEARLEESTNYNQQLRHELKTVKK-NYEALKQRQDEERMVQSSIPvsgeddkwgrESQEATRELLKVKDRLi 1049
Cdd:TIGR01612 1891 DEAEKIFINISKLANSINIQIQNNSGIDLFDNiNIAILSSLDSEKEDTLKFIP----------SPEKEPEIYTKIRDSY- 1959
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1050 evernNATLQAEKQALKTQLKQLETQN-NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL 1128
Cdd:TIGR01612 1960 -----DTLLDIFKKSQDLHKKEQDTLNiIFENQQLYEKIQASNELKDTLSDLKYKKEKILNDVKLLLHKFDELNKLSCDS 2034
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1129 LIQQSSLENENESIMKEREDLKSlydaliKDHEKLELLHERQASE--YESLISKHGTLKSAHKNLEVEHKDLEDRYNQLL 1206
Cdd:TIGR01612 2035 QNYDTILELSKQDKIKEKIDNYE------KEKEKFGIDFDVKAMEekFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNII 2108
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1207 KQKGQLEDLEKMIKTEQEKM---LLESKNHEVVASEYKKLCgendrLNYTYSQLLKeteilqmdhkNLKS-VLNNSKLEQ 1282
Cdd:TIGR01612 2109 QSKKKLKELTEAFNTEIKIIedkIIEKNDLIDKLIEMRKEC-----LLFSYATLVE----------TLKSkVINHSEFIT 2173
|
1130 1140 1150 1160 1170 1180
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 1283 TrlEAEFSKlkEQYQQLDITSTKLNNQCELLsQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMES 1348
Cdd:TIGR01612 2174 S--AAKFSK--DFFEFIEDISDSLNDDIDAL-QIKYNLNQTKKHMISILADATKDHNNLIEKEKEA 2234
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
594-837 |
7.01e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.70 E-value: 7.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 594 ESIKETCGKLSKIEFEKRQMKKELELYKEKgerAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENR 673
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE---EKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 674 KFKKTLDSFKN-LTFQLESLEKENSQldeENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKglelmrasfkKTE 752
Cdd:COG4942 94 ELRAELEAQKEeLAELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRA----------DLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKK 832
Cdd:COG4942 161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA---AELAELQQEAEELEALIARLEAEAA 237
|
....*
gi 1720363745 833 QLEKE 837
Cdd:COG4942 238 AAAER 242
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1347 |
8.77e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.08 E-value: 8.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 883 LKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKT---QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYK 955
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 956 LLESKLESTLKKSLEIKEEKIAALEARLEEStnynQQLRHELKTVKKNYEALKQRQDEERMVQSsipvsgedDKWGRESQ 1035
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLS--------LATEEELQ 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQiLALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:COG4717 196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-ERLKEARLLLLIAAALLALLGLGGSLLSLILT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1116 SQ-----STSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDH-EKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:COG4717 275 IAgvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELlAALGLPPDLSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1190 NL-----EVEHKDLEDRYNQLLKQKGQ--LEDLEKMIKTEQEKMLLESKNHEVvaseykklcgeNDRLNYTYSQLLKETE 1262
Cdd:COG4717 355 EAeeleeELQLEELEQEIAALLAEAGVedEEELRAALEQAEEYQELKEELEEL-----------EEQLEELLGELEELLE 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1263 ILqmDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL--LSQLKGNLEEENRHLLDQIQTLMLQnRT 1340
Cdd:COG4717 424 AL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELaeLLQELEELKAELRELAEEWAALKLA-LE 500
|
....*..
gi 1720363745 1341 LLEQNME 1347
Cdd:COG4717 501 LLEEARE 507
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1158 |
8.88e-08 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 57.61 E-value: 8.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 796 LQKSLEELKissKRlEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKE 872
Cdd:PRK11281 41 VQAQLDALN---KQ-KLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 873 INvykeSCVRLKELEKE-NKELVKRATIDiKTLVTLREDLVS-----EKLKTQQMNND--LEKLTHELEKIGLNKERLLH 944
Cdd:PRK11281 117 TL----STLSLRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSlqtqpERAQAALYANSqrLQQIRNLLKGGKVGGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 945 DEQSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKknyEAL--KQRQDEERMVQSSIp 1022
Cdd:PRK11281 192 SQRVLLQAEQALLNAQND-LQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQ---EAInsKRLTLSEKTVQEAQ- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1023 vSGEDDKWGRESQEATREL---LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL------------Q 1087
Cdd:PRK11281 267 -SQDEAARIQANPLVAQELeinLQLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLkgslllsrilyqQ 345
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 1088 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SIMKEREDlksLYDALIK 1158
Cdd:PRK11281 346 QQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDERRE---LLDQLNK 421
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1180 |
1.02e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.39 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL--EKENKTLFKEINVYKEScVRLKELEKENKELVK-RATID 900
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLrrEREKAERYQALLKEKRE-YEGYELLKEKEALERqKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 901 iKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTlkksleikEEKIAALE 980
Cdd:TIGR02169 244 -RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--------ERSIAEKE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 981 ARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERmvqssipvsGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQA 1060
Cdd:TIGR02169 315 RELEDAEERLAKLEAEIDKLLAEIEELEREIEEER---------KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1061 EKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE 1140
Cdd:TIGR02169 386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1720363745 1141 SIMKEREDLKSLYDALIKDHEKLE-----LLHERQASEYESLISK 1180
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQrelaeAEAQARASEERVRGGR 510
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-934 |
1.45e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 726 ENKELESEKEQLRKGLELMRASFKKTERLEVSYQG----LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 802 ELKIS-SKRLEQLEKENKSLE-------QETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:COG4942 101 AQKEElAELLRALYRLGRQPPlalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 874 NVYKESCVRLKELEKENKELVKRATidiKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
743-897 |
1.61e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 56.40 E-value: 1.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 743 LMRASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQ 822
Cdd:COG2433 382 LEELIEKELPEEEPEAEREKEHEERELTEEE---EEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARS 455
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720363745 823 ET-SQLEKDKK--QLEKENKRLRQQAEIKDTTLEENNVKignLEKENKTLFKEInvyKESCVRLKELEKENKELVKRA 897
Cdd:COG2433 456 EErREIRKDREisRLDREIERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-868 |
1.92e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 56.62 E-value: 1.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmnllsdarsarmyrDELDALREKAVRVDKLESELSRYKErlhdie 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLELESEIIELKKSLS------ 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 341 fykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN-----LQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Cdd:COG5022 917 ------SDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPelnklHEVESKLKETSEEYEDLLKKSTILVREGNKA 990
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 416 EMAQKQSMDESLHLGWELEQISRTSELAeapqKSLGHEVNELTS-SKLLKLEMENQSLTKTVEELRSTADSAAGSTS--- 491
Cdd:COG5022 991 NSELKNFKKELAELSKQYGALQESTKQL----KELPVEVAELQSaSKIISSESTELSILKPLQKLKGLLLLENNQLQary 1066
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 492 KILKVEKENQRLNKK-------VEILENEiIQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLR--ENSERQIKILEQE 559
Cdd:COG5022 1067 KALKLRRENSLLDDKqlyqlesTENLLKT-INVKDLEVTNRNLVKPANVLqfiVAQMIKLNLLQEisKFLSQLVNTLEPV 1145
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 560 NEHLNQT---------VSSLRQRSQISAEARVKDIEKenkiLHESIKETCGKLSKIefekrqmkkELELYKEKGERAEEL 630
Cdd:COG5022 1146 FQKLSVLqleldglfwEANLEALPSPPPFAALSEKRL----YQSALYDEKSKLSSS---------EVNDLKNELIALFSK 1212
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 631 ENELNHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE--------NSQLDE 701
Cdd:COG5022 1213 IFSGWPRGDKLKKLISEGWVPTEYSTSLkGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEeevlpatiNSLLQY 1292
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 702 ENLELRRSVeSLKCASMRMAQLQLENKELESEKE-QLRKGLELMRASFKKTER----LEVSYQGLDTENQRLQKALENSN 776
Cdd:COG5022 1293 INVGLFNAL-RTKASSLRWKSATEVNYNSEELDDwCREFEISDVDEELEELIQavkvLQLLKDDLNKLDELLDACYSLNP 1371
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 777 KKIQQLESELQDLEMENQTLQKSLEELKISS--KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTleE 854
Cdd:COG5022 1372 AEIQNLKSRYDPADKENNLPKEILKKIEALLikQELQLSLEGKDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL--S 1449
|
650
....*....|....
gi 1720363745 855 NNVKIGNLEKENKT 868
Cdd:COG5022 1450 ALLTKEKIALLDRK 1463
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-894 |
3.24e-07 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 54.69 E-value: 3.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 508 EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 582 VKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE-----LYKEKgERAEELENELNHLGKENELLQKKITNLKitcE 656
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEalerqLAAET-EQNRALEEENKALREEAQAAEKALQRAE---G 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 657 KLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESlKCASMR------MAQLQLENKEL 730
Cdd:pfam19220 161 ELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVEAH 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 731 ESEKEQLRKGLELMRASFKKTERLevsyqgldtenqrlqkalensnkkIQQLESELQDLEMENQTLQKSLEELKIS---- 806
Cdd:pfam19220 240 RAERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErdtl 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScvrlkeL 886
Cdd:pfam19220 296 ERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAA------L 369
|
....*...
gi 1720363745 887 EKENKELV 894
Cdd:pfam19220 370 EQANRRLK 377
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
991-1208 |
3.25e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 3.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 991 QQLRHELKTVKKNYEALKQRQDEERMVQSSIpvSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1070
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKAL--LKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1071 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1149 LKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQ 1208
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
3.40e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.51 E-value: 3.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 559 ENEHLNQTVSSLRQRSQISAEARVKDIEK-ENKILHESIKETCGKLSK----IEFEK-RQ--MKKELELYKEKGERAEEL 630
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERrrklEEAEKaRQaeMDRQAAIYAEQERMAMER 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 631 ENELNHLGKEN---ELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Cdd:pfam17380 347 ERELERIRQEErkrELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 708 RSVESLKcasmrmaqlQLENKELESEKEQlrkglELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESElq 787
Cdd:pfam17380 427 AEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE-- 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 788 dlEMENQTLQKSLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK--E 865
Cdd:pfam17380 491 --EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKatE 563
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1720363745 866 NKTLFKEINVYKESCVRLKELEKENKELvkRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 564 ERSRLEAMEREREMMRQIVESEKARAEY--EATTPITTIKPIYRPRISE 610
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
764-1014 |
3.96e-07 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 54.93 E-value: 3.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 764 ENQRLQKALENS---NKKIQQLESELQDLEMENQTLQ----KSLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:PRK05771 41 SNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKELE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 836 KENKRLRqqaeikdttleennvKIGNLEKENKTLFKEINVYkescVRLKELEKENKELVKrATIDIKTLVTLRED----- 910
Cdd:PRK05771 121 QEIERLE---------------PWGNFDLDLSLLLGFKYVS----VFVGTVPEDKLEELK-LESDVENVEYISTDkgyvy 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 911 --LVSEKlktqqmnNDLEKLTHELEKIGLnkerllhdeqstddSRYKLLESKlesTLKKSLEIKEEKIAALEARLEEstn 988
Cdd:PRK05771 181 vvVVVLK-------ELSDEVEEELKKLGF--------------ERLELEEEG---TPSELIREIKEELEEIEKERES--- 233
|
250 260
....*....|....*....|....*.
gi 1720363745 989 ynqqLRHELKTVKKNYEALKQRQDEE 1014
Cdd:PRK05771 234 ----LLEELKELAKKYLEELLALYEY 255
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
512-858 |
5.27e-07 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 54.31 E-value: 5.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 512 NEIIQEKQSL-QNCQNLSKD---LMKEKAQLEKTIETLRENSER--------------------QIKILEQENEHLNQTV 567
Cdd:pfam05622 3 SEAQEEKDELaQRCHELDQQvslLQEEKNSLQQENKKLQERLDQlesgddsgtpggkkylllqkQLEQLQEENFRLETAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 568 SSLRQRSQIsaearvkdIEKENKILHESIKEtcgkLSKIEFEKRQMKKELELYKEKGERAEELE----------NELNHL 637
Cdd:pfam05622 83 DDYRIKCEE--------LEKEVLELQHRNEE----LTSLAEEAQALKDEMDILRESSDKVKKLEatvetykkklEDLGDL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 638 GKENELLQKKITN-LKITCE-------------KLETLEQENSELER----ENRKFKKTLDSFKNLTFQLESLEKENSQL 699
Cdd:pfam05622 151 RRQVKLLEERNAEyMQRTLQleeelkkanalrgQLETYKRQVQELHGklseESKKADKLEFEYKKLEEKLEALQKEKERL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 700 DEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRK-GLELMRASFKKT-ERLEVSYQGLD-----TENQR---LQ 769
Cdd:pfam05622 231 IIERDTLRETNEELRCAQLQQAELSQADALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRlgqegSYRERlteLQ 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 770 KALENSNKKIQQLESEL-----QDLEMENQT--LQKSLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam05622 311 QLLEDANRRKNELETQNrlanqRILELQQQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELE 390
|
410 420
....*....|....*....|
gi 1720363745 839 KRLRQQAEIKDTTLEENNVK 858
Cdd:pfam05622 391 PKQDSNLAQKIDELQEALRK 410
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-988 |
7.01e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.61 E-value: 7.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 746 ASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeinvykescVRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-----------QYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeqSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL----ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAA 237
|
....
gi 1720363745 985 ESTN 988
Cdd:COG4942 238 AAAE 241
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
547-867 |
7.59e-07 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 54.52 E-value: 7.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHEsiKETC-GKLSKIEFEKRQMKKELELYKEKGE 625
Cdd:PLN02939 117 TNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTE--KEALqGKINILEMRLSETDARIKLAAQEKI 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 626 RAEELENELNHLgkENELLQKKITNLKITC---EKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDee 702
Cdd:PLN02939 195 HVEILEEQLEKL--RNELLIRGATEGLCVHslsKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLD-- 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 703 nlelrrsveslkcASMRmaqlQLENKELESEKEQLRKGLELMRASFKKTERLEVsyqgldtenqRLQKALENSNKKIQQL 782
Cdd:PLN02939 271 -------------ASLR----ELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD----------LLDRATNQVEKAALVL 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 783 ESElQDLEMENQTLQKSLEE---LKISSKRLEQLEKENKSLEQetsqlekdkkQLEKENKRLRQQAEIKDTTLEENNVKI 859
Cdd:PLN02939 324 DQN-QDLRDKVDKLEASLKEanvSKFSSYKVELLQQKLKLLEE----------RLQASDHEIHSYIQLYQESIKEFQDTL 392
|
....*...
gi 1720363745 860 GNLEKENK 867
Cdd:PLN02939 393 SKLKEESK 400
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1148 |
1.10e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRyKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRHE 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-AALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 997 LKTVKKNY-EALKQRQDEERMVQSSIPVSGEDdkwgreSQEATRellkvkdRLIEVERNNATLQAEKQALKTQLKQLETQ 1075
Cdd:COG4942 99 LEAQKEELaELLRALYRLGRQPPLALLLSPED------FLDAVR-------RLQYLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 1076 NNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
501-1418 |
1.24e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.90 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 501 QRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQL--EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQiSA 578
Cdd:TIGR00606 196 QTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLesSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIK-AL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 579 EARVKDIEKENKILHEsiketcgKLSKIEFEKRQMKKELELY-----KEKGERAEELENELNHLGKENELLQKKITNLKI 653
Cdd:TIGR00606 275 KSRKKQMEKDNSELEL-------KMEKVFQGTDEQLNDLYHNhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLV 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 654 TCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESE 733
Cdd:TIGR00606 348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 734 KEQLR-KGLELMRASFKKTERLEvsyqgldtenqRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKR--L 810
Cdd:TIGR00606 428 ADEIRdEKKGLGRTIELKKEILE-----------KKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNslT 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL---EENNVKIGNLEKENKTLFKEINVYKESCVRLKELE 887
Cdd:TIGR00606 497 ETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLE 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnkERLLHDEQSTDDsryklLESKLEStLKK 967
Cdd:TIGR00606 577 DWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY----EDKLFDVCGSQD-----EESDLER-LKE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 968 SLEIKEEKIAALEARLEESTNYNQQLRHElktvkknyealkqrqdeermVQSSIPVSGEDDKWGRESQEATRELlKVKDR 1047
Cdd:TIGR00606 647 EIEKSSKQRAMLAGATAVYSQFITQLTDE--------------------NQSCCPVCQRVFQTEAELQEFISDL-QSKLR 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1048 LIEVErnnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1127
Cdd:TIGR00606 706 LAPDK-----LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE 780
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1128 LliqqsslenenesimKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDledryNQLLK 1207
Cdd:TIGR00606 781 E---------------ESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQ-----HELDT 840
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1208 QKGQLEDLEKMIKTEQEKML-LESKNHEVvaSEYKKLCGENDRlnyTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLE 1286
Cdd:TIGR00606 841 VVSKIELNRKLIQDQQEQIQhLKSKTNEL--KSEKLQIGTNLQ---RRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLE 915
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1287 aefsKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENrhlLDQIQTLMlqnRTLLEQNMESKDLFHVEQRQYIDK---- 1362
Cdd:TIGR00606 916 ----TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK---VKNIHGYM---KDIENKIQDGKDDYLKQKETELNTvnaq 985
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 1363 LNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSL 1418
Cdd:TIGR00606 986 LEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHL 1041
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
611-1183 |
1.34e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 1.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 611 RQMKKELELYKEKGERAEELENELNHLGKENELlqkkitnlkitCEKLETLEQENSELEREnrkfKKTLDSFKNLTfQLE 690
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEPIREL-----------AERYAAARERLAELEYL----RAALRLWFAQR-RLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 691 SLEKEnsqLDEENLELRRSVEslkcasmRMAQLQLENKELESEKEQLRKglELMRASFKKTERLEvsyqgldTENQRLQK 770
Cdd:COG4913 292 LLEAE---LEELRAELARLEA-------ELERLEARLDALREELDELEA--QIRGNGGDRLEQLE-------REIERLER 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSK-RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaEIKD 849
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 850 ttLEENNVKI-GNLEKENKTLFKEINVYKESC--------VRLKEL-------------------EKENKELVKRATIDI 901
Cdd:COG4913 431 --LERRKSNIpARLLALRDALAEALGLDEAELpfvgelieVRPEEErwrgaiervlggfaltllvPPEHYAAALRWVNRL 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 902 KT---LVTLREDLVSEKLKTQQMNND--LEKLT-----------HELEKI-----------------GLNKERLLHDEQS 948
Cdd:COG4913 509 HLrgrLVYERVRTGLPDPERPRLDPDslAGKLDfkphpfrawleAELGRRfdyvcvdspeelrrhprAITRAGQVKGNGT 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 949 T---DDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDeermvqssipVSG 1025
Cdd:COG4913 589 RhekDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE----------YSW 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1026 EDDKWgresQEATRELLKVKDRLIEVERNNATLQAekqaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1105
Cdd:COG4913 659 DEIDV----ASAEREIAELEAELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD 730
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKE-REDLKSLYDALIKDHEKLELLHERQASEYESLISKHGT 1183
Cdd:COG4913 731 ELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENlEERIDALRARLNRAEEELERAMRAFNREWPAETADLDA 809
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-697 |
1.54e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.43 E-value: 1.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 183 QEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 263 LRQELEEKTEQLLD----CKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKERLHD 338
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 339 IEfykarveelKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENlQLKAKLHDMEMERDMDRKKIEELMEENMTLEMA 418
Cdd:TIGR00618 544 EE---------DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDN-RSKEDIPNLQNITVRLQDLTEKLSEAEDMLACE 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 419 QKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSskLLKLEMENQSLTKTVEELRSTAdsaagstskilkvek 498
Cdd:TIGR00618 614 QHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLT--LTQERVREHALSIRVLPKELLA--------------- 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 499 ENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:TIGR00618 677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 579 EARVKDieKENKILHESIKETCG-KLSKIEFEKRQMKKELE-LYKEKGERAEELENELNHLGKENELLQKKI-------- 648
Cdd:TIGR00618 757 KARTEA--HFNNNEEVTAALQTGaELSHLAAEIQFFNRLREeDTHLLKTLEAEIGQEIPSDEDILNLQCETLvqeeeqfl 834
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1720363745 649 TNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENS 697
Cdd:TIGR00618 835 SRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQ 883
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
658-1262 |
2.95e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 52.52 E-value: 2.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 658 LETLEQENSELERE----NRKFKKTLDSFKnlTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESE 733
Cdd:pfam10174 5 LRDLQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 734 KEQLRKGLELMRASFKKTERlevsyqglDTENQRLQKALENSNkkIQQLESELQDLEMENQTLQKSLE--ELKISSKRlE 811
Cdd:pfam10174 83 LRAQRDLNQLLQQDFTTSPV--------DGEDKFSTPELTEEN--FRRLQSEHERQAKELFLLRKTLEemELRIETQK-Q 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 812 QLEKENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeinvyKESCVRLKELEKE 889
Cdd:pfam10174 152 TLGARDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPD 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 890 NKElvkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD--------SRYKLLESKL 961
Cdd:pfam10174 225 PAK--------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevykSHSKFMKNKI 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 962 EsTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDeerMVQSsipvsgEDDKWGRESQEATREL 1041
Cdd:pfam10174 292 D-QLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAA---ILQT------EVDALRLRLEEKESFL 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1042 LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1121
Cdd:pfam10174 362 NKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTL 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1122 MNQNA------QLLIQQSSLEN-----ENESIMKEREDLKSLYDALIKDHEKLEL----LHERQASEYESLISKHGTLKS 1186
Cdd:pfam10174 442 EEALSekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKS 521
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 1187 AHKNLEVEHKDLEDRYNQLLKQKgQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLnytySQLLKETE 1262
Cdd:pfam10174 522 LEIAVEQKKEECSKLENQLKKAH-NAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERL----LGILREVE 592
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-1038 |
3.01e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.53 E-value: 3.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 326 ESElsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRkki 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIR--- 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 406 eelmeenmtlemaqkqsmdeslhlgwelEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADS 485
Cdd:pfam12128 404 ----------------------------EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQ 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 486 AAGSTSKILKVEKENQRLNKkveileneiIQEKQSLQNcqnlskdlmkeKAQLEKTIETLRENSERqikilEQENEHLNQ 565
Cdd:pfam12128 456 ATATPELLLQLENFDERIER---------AREEQEAAN-----------AEVERLQSELRQARKRR-----DQASEALRQ 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 566 TVSSLRQRSQISAEARVKDIEKENKILH------ESIKETCGKLSKIEFEKRQmkkelelykekgeraeELENELNHLGK 639
Cdd:pfam12128 511 ASRRLEERQSALDELELQLFPQAGTLLHflrkeaPDWEQSIGKVISPELLHRT----------------DLDPEVWDGSV 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 640 ENELlqkKITNLKITCEKLETLE--QENSELERENRKFKKTLDSFKNLTFQLES-LEKENSQLDEENLELRRSVESLKCA 716
Cdd:pfam12128 575 GGEL---NLYGVKLDLKRIDVPEwaASEEELRERLDKAEEALQSAREKQAAAEEqLVQANGELEKASREETFARTALKNA 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 717 SMRMAQLqleNKELESEKEQLRKGLElmRASFKKTERLevsyQGLDTEnqrlQKALENsnkKIQQLESELQDLEMENQTl 796
Cdd:pfam12128 652 RLDLRRL---FDEKQSEKDKKNKALA--ERKDSANERL----NSLEAQ----LKQLDK---KHQAWLEEQKEQKREART- 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 797 QKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRlrqqaEIKDTTLEENNvkIGNLEKENKTLFKeinvy 876
Cdd:pfam12128 715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKR-----DLASLGVDPDV--IAKLKREIRTLER----- 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 877 kescvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE-KLTHELEKIGLNKERLLHDEQSTDDSRYK 955
Cdd:pfam12128 783 -----KIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQqQLARLIADTKLRRAKLEMERKASEKQQVR 857
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 956 LLE--SKLESTLKKSLEIKEEKIAA-LEARLEESTNYNQQLRHELKTVKknyEALKQRQDEERMVQSSIPVSGEDDKWGR 1032
Cdd:pfam12128 858 LSEnlRGLRCEMSKLATLKEDANSEqAQGSIGERLAQLEDLKLKRDYLS---ESVKKYVEHFKNVIADHSGSGLAETWES 934
|
....*.
gi 1720363745 1033 ESQEAT 1038
Cdd:pfam12128 935 LREEDH 940
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
482-1301 |
3.01e-06 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 52.53 E-value: 3.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 482 TADSAAGSTSKILKVEKenqRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqene 561
Cdd:PTZ00440 430 IADYALYSNLEIIEIKK---KYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE---- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 562 hLNQTVSSLRQRSQISAEaRVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKEN 641
Cdd:PTZ00440 503 -LLQIINSIKEKNNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENV 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 642 ELLQKKITNLKITCEKLETLEQENSELERENRKFKKtldsfknltfqleslEKENSQLDEENLELRRSVESLKCASMRMA 721
Cdd:PTZ00440 581 DHIKDIISLNDEIDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELS 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 722 QLQLENKELESEKEQLRKGLELMRASFKKTERLEvsyqgldtenqrlQKALENSNKKIQQLESELQDL-EMENQTLQKSL 800
Cdd:PTZ00440 646 HFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQL 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 801 EELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLFKEINVYKES 879
Cdd:PTZ00440 713 NNIEQDiSNSLNQYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDT 788
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKERLLHDEqstDDSRYKLLES 959
Cdd:PTZ00440 789 ILNKENKISNDINILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDENLNLKE---LEKEFNENNQ 863
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 960 KLESTLKKSLEI--KEEKIAALEARLEESTNYNQQLRHelktVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESqEA 1037
Cdd:PTZ00440 864 IVDNIIKDIENMnkNINIIKTLNIAINRSNSNKQLVEH----LLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLN-NL 938
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1038 TRELLKVKDRLIEVERNNATLQAEKQaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENstlnsq 1117
Cdd:PTZ00440 939 NKEKEKIEKQLSDTKINNLKMQIEKT-LEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILN------ 1011
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1118 stslmnqnaqlliqqsslENENESIMKEREDLKSLYDALIKdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKD 1197
Cdd:PTZ00440 1012 ------------------KKIDDLIKKQHDDIIELIDKLIK--EKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYK 1071
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1198 LEDRYNQLLKQKGQLEDLEKMIKTEQEKML-LESKNHEVVASeykkLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLN 1276
Cdd:PTZ00440 1072 NPKIKEEIKLLEEKVEALLKKIDENKNKLIeIKNKSHEHVVN----ADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELE 1147
|
810 820
....*....|....*....|....*
gi 1720363745 1277 NSKLEQTRLEaEFSKLKEQYQQLDI 1301
Cdd:PTZ00440 1148 NMNLEDITLN-EVNEIEIEYERILI 1171
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
726-1328 |
4.24e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.89 E-value: 4.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 726 ENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALE----NSNKKIQQLESELQDLEMENQTLQKSLE 801
Cdd:TIGR00618 164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPcmpdTYHERKQVLEKELKHLREALQQTQQSHA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 802 ELKisskRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT-----LEENNVKIGNLEKENKTLFKEINVY 876
Cdd:TIGR00618 244 YLT----QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHIKAVTQIEQQAQRIHTELQSK 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 877 KEScvRLKELEKENKELVKRAtiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQStddsryKL 956
Cdd:TIGR00618 320 MRS--RAKLLMKRAAHVKQQS--SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ------KT 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 957 LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALK-QRQDEERMVQSSIPVSGEDDKWGRESQ 1035
Cdd:TIGR00618 390 TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAElCAAAITCTAQCEKLEKIHLQESAQSLK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:TIGR00618 470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGP-LTRRMQRGEQTYAQLETSEEDVY 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1116 SQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKsahknLEVEH 1195
Cdd:TIGR00618 549 HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL-----RKLQP 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1196 KDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVAS--EYKKLCGENDRLNYTYSQLLKETeiLQMDHKNLKS 1273
Cdd:TIGR00618 624 EQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSirVLPKELLASRQLALQKMQSEKEQ--LTYWKEMLAQ 701
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1274 VLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1328
Cdd:TIGR00618 702 CQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
958-1299 |
5.26e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 5.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 958 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRHElKTVKKNYEALKQRQDEermvqssipvsgeddkwgRESQEA 1037
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKRE------------------YEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1114
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1115 -----NSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1190 NLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEvvaSEYKKLCGENDRLNYTYSQLLKETEILQMDHK 1269
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE---AKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350
....*....|....*....|....*....|
gi 1720363745 1270 NLKSVLNNSKLEQTRLEAEFSKLKEQYQQL 1299
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-580 |
6.10e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 6.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDES 426
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 427 LHLGWELEQISRTSELAEApqkslghevneLTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKK 506
Cdd:COG4942 107 AELLRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720363745 507 VEILENEIIQEKQSLQncqnlskDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Cdd:COG4942 176 LEALLAELEEERAALE-------ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
6.18e-06 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 48.85 E-value: 6.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 716 ASMRMAQLQLENKELESEKEQLRKGLELMRASFKKterLEVSYQGLDTENQRLQKALEnsnkKIQQLESELQDLEMENQT 795
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQEQLAELRQENQE---LKQQLSTLEAELEELQKELE----RIKQISANAIELDEENRE 136
|
90 100 110
....*....|....*....|....*....|.
gi 1720363745 796 LQKSLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 137 LREELAELK---QENEALEAENERLQENEQR 164
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
663-1016 |
8.04e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 51.06 E-value: 8.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 663 QENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLelrRSVESLKCASMR------MAQLQLENKELESEKEQ 736
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSL---RTVMELPQKSTSsdddhnRASMQRDEAIAAIDNEQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 737 LRKglelmrasfKKTERLEVSYQGLDtenqrLQKALENSNKKIQQLESE----LQDLE---MENQTLQKsleELKISSKR 809
Cdd:PLN02939 116 QTN---------SKDGEQLSDFQLED-----LVGMIQNAEKNILLLNQArlqaLEDLEkilTEKEALQG---KINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKE---- 885
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAEteer 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 886 ---LEKEN-------KELVKR---ATIDIKTLVTLREDLVSEKLKTQQMNndLEKLTHELEKIGLnkerLLHDEQSTDDS 952
Cdd:PLN02939 259 vfkLEKERslldaslRELESKfivAQEDVSKLSPLQYDCWWEKVENLQDL--LDRATNQVEKAAL----VLDQNQDLRDK 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 953 RYKLLESKLESTLKK----SLEIKEEKIAALEARL----EESTNYNQQLRHELKTVKKNYEALKQRQDEERM 1016
Cdd:PLN02939 333 VDKLEASLKEANVSKfssyKVELLQQKLKLLEERLqasdHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSL 404
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
882-1374 |
8.09e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 8.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLK-TQQMNNDLEKLTHELEKIGLNKERLlhdeqstDDSRYKLLESK 960
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLReINEISSELPELREELEKLEKEVKEL-------EELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 961 LE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRH------ELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRE 1033
Cdd:PRK03918 245 KElESLEGSKRKLEEKIRELEERIEELKKEIEELEEkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1034 S-QEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENs 1112
Cdd:PRK03918 325 GiEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRLTGLTPEKLEKELEE- 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1113 tLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKS------LYDALIKDHEKLELLherqaSEYESLIskhgtlks 1186
Cdd:PRK03918 396 -LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTEEHRKELL-----EEYTAEL-------- 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1187 ahKNLEVEHKDLEDRYNQLLKQkgqLEDLEKMIKTEQEKMLLESKNHEVVASEyKKLCGENdrlnytysqlLKETEILQM 1266
Cdd:PRK03918 462 --KRIEKELKEIEEKERKLRKE---LRELEKVLKKESELIKLKELAEQLKELE-EKLKKYN----------LEELEKKAE 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1267 DHKNLKSVLNNSKLEQTRLEAEFSKLKEqyqqlditstkLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1346
Cdd:PRK03918 526 EYEKLKEKLIKLKGEIKSLKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594
|
490 500
....*....|....*....|....*...
gi 1720363745 1347 ESKDLFHVEQRQYIDKLNELRRQKEKLE 1374
Cdd:PRK03918 595 KELEPFYNEYLELKDAEKELEREEKELK 622
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
820-1382 |
8.50e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 50.88 E-value: 8.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 820 LEQETSQLEKDKKQLEKENKRLRQ---QAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE---NKEL 893
Cdd:pfam05483 101 LKQKENKLQENRKIIEAQRKAIQElqfENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKyeyEREE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 894 VKRATIDIKTLVTlREDLVSEKLKTQQMNNDLE---KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLEstlkksle 970
Cdd:pfam05483 181 TRQVYMDLNNNIE-KMILAFEELRVQAENARLEmhfKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITE-------- 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 971 iKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKwgrESQEATRELLKVKDRLI- 1049
Cdd:pfam05483 252 -KENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSM---STQKALEEDLQIATKTIc 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1050 --------EVERNN--------------ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQntTLQTQNAKL 1107
Cdd:pfam05483 328 qlteekeaQMEELNkakaahsfvvtefeATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEM--TKFKNNKEV 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1108 QVEnstlnsQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSA 1187
Cdd:pfam05483 406 ELE------ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1188 HKNLEVEHKDLEDRYNQLLKQKgqledleKMIKTEQEKMLLESKNHEVVASEYKKlcgendrlnyTYSQLLKETEILQMD 1267
Cdd:pfam05483 480 LEKEKLKNIELTAHCDKLLLEN-------KELTQEASDMTLELKKHQEDIINCKK----------QEERMLKQIENLEEK 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1268 HKNLKSVLNNSKLE----QTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLE 1343
Cdd:pfam05483 543 EMNLRDELESVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622
|
570 580 590
....*....|....*....|....*....|....*....
gi 1720363745 1344 QNMESKDLFHVEQRQYIDKLNELRRQKEKLEEkIMDQYK 1382
Cdd:pfam05483 623 KGSAENKQLNAYEIKVNKLELELASAKQKFEE-IIDNYQ 660
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
253-714 |
9.69e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 50.67 E-value: 9.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAvrvDKLESELSRY 332
Cdd:PRK01156 185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMK---NRYESEIKTA 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 333 KERLHDIEFYKARVEELKEDNQVLLETKTM------------------LEDQLEGTRARSDKLHELEKENLQLKAKLHD- 393
Cdd:PRK01156 262 ESDLSMELEKNNYYKELEERHMKIINDPVYknrnyindyfkykndienKKQILSNIDAEINKYHAIIKKLSVLQKDYNDy 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 394 MEMERDMD--RKKIEELMEENM-------TLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELT------ 458
Cdd:PRK01156 342 IKKKSRYDdlNNQILELEGYEMdynsylkSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINvklqdi 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 459 SSKLLKLEMENQSLTKTVEELRSTADSAAG-----------STSKILKVEK----ENQRLNKKVEILENEI--IQEK--- 518
Cdd:PRK01156 422 SSKVSSLNQRIRALRENLDELSRNMEMLNGqsvcpvcgttlGEEKSNHIINhyneKKSRLEEKIREIEIEVkdIDEKivd 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 519 -------------QSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSslrQRS 574
Cdd:PRK01156 502 lkkrkeyleseeiNKSINEYNKIESARADLEDIKIKINELKDKHDKyeeiknrykslKLEDLDSKRTSWLNALA---VIS 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 575 QISAEARVKDIEKENKILHESIKETCGKLSKIEFEK-------RQMKKELELYKEKGERAEELENELNHLGKENELLQKK 647
Cdd:PRK01156 579 LIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKsyidksiREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQ 658
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 648 ITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEK----ENSQLDEENLELRRSVESLK 714
Cdd:PRK01156 659 IAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEilrtRINELSDRINDINETLESMK 729
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
719-865 |
1.02e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.77 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTE----RLEVSYQGLDTENQRLQKALEN--SNKKIQQLESELQDLEME 792
Cdd:COG1579 25 RLKELPAELAELEDELAALEARLEAAKTELEDLEkeikRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRR 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 793 NQTLQKSLEELkisskrLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:COG1579 105 ISDLEDEILEL------MERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-695 |
1.45e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.78 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 577 SAEARVKDIEKE-NKILHESIKE--TCGKLSKIEFEKRQMKKELELYKEKGERaeelENELNHLgkENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEaeAIKKEALLEAKEEIHKLRNEFEKELRER----RNELQKL--EKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1720363745 654 tcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
792-1089 |
1.64e-05 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 48.80 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 792 ENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFK 871
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 872 EINVYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD 950
Cdd:pfam09728 82 QNKKLKeESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 951 DSRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQ------------RQDEE 1014
Cdd:pfam09728 162 ELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDtlnksnevfttfKKEME 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1015 RMVQSSIPVSGEDDKWGRESQEATRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam09728 242 KMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
255-379 |
1.83e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 255 DAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENM------NLLSDARSARMYRDELDALREKAVRVDKLESE 328
Cdd:COG4913 607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalqrlaEYSWDEIDVASAEREIAELEAELERLDASSDD 686
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 329 LSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Cdd:COG4913 687 LAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQAEEELDELQD 734
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
253-782 |
1.95e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.74 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmnllsdarsaRMYRDELDALREKAVRVDKLESELSRY 332
Cdd:pfam05557 99 LADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERL----------DLLKAKASEAEQLRQNLEKQQSSLAEA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 333 KERLHDIEF----YKARVEELKEDNQVLLETKTMlEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDmdrkKIEEL 408
Cdd:pfam05557 169 EQRIKELEFeiqsQEQDSEIVKNSKSELARIPEL-EKELERLREHNKHLNENIENKLLLKEEVEDLKRKLE----REEKY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 409 MEENMTLEMaqkqsmdESLHLGWELEQISRTselaeAPQKSLGHEVNELTSSKLLKLEMENQSLtktVEELRStadsaag 488
Cdd:pfam05557 244 REEAATLEL-------EKEKLEQELQSWVKL-----AQDTGLNLRSPEDLSRRIEQLQQREIVL---KEENSS------- 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 489 STSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREnserqikILEQENEHLNQTVS 568
Cdd:pfam05557 302 LTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRA-------ILESYDKELTMSNY 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 569 SLRQRSQIsaearvkdiekenKILHESIKETCGKLSKIEFEKRQMKKELELYKekgERAEELENELNHLGKENELLQKKI 648
Cdd:pfam05557 375 SPQLLERI-------------EEAEDMTQKMQAHNEEMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLADPSY 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 649 TNLKITC--EKLETLEQENSELEREnrkfKKTLDSfknltfqleSLEKENSQLDEENLELRRSVESLKCASMRMAQLQLE 726
Cdd:pfam05557 439 SKEEVDSlrRKLETLELERQRLREQ----KNELEM---------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQ 505
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 727 NKELESEKEQLRKGLELMRASFKKTERL-EVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:pfam05557 506 LEKLQAEIERLKRLLKKLEDDLEQVLRLpETTSTMNFKEVLDLRKELESAELKNQRL 562
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-822 |
2.25e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 2.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 332 YKERLHDIEF---------------YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHElEKENLQLK-----AKL 391
Cdd:COG4913 364 LEALLAALGLplpasaeefaalraeAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA-EIASLERRksnipARL 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 392 HDM--EMERDMDRKKIE-----ELME---ENMTLEMA-------QKQSM-------------DESLHLGWEL-----EQI 436
Cdd:COG4913 443 LALrdALAEALGLDEAElpfvgELIEvrpEEERWRGAiervlggFALTLlvppehyaaalrwVNRLHLRGRLvyervRTG 522
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 437 SRTSELAEAPQKSLGHEVnELTSSKL---LKLEMENQ-SLTK--TVEELRSTADS--AAGSTSKILKV-EKENQRLN--- 504
Cdd:COG4913 523 LPDPERPRLDPDSLAGKL-DFKPHPFrawLEAELGRRfDYVCvdSPEELRRHPRAitRAGQVKGNGTRhEKDDRRRIrsr 601
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 505 --------KKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEK---TIETLRENSERQIKILEQENEhlnqtvssLRQr 573
Cdd:COG4913 602 yvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEIDVASAERE--------IAE- 672
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 574 sqisAEARVKDIEKENKILhesiketcgklskiefekRQMKKELElykEKGERAEELENELNHLGKENELLQKKITNLKI 653
Cdd:COG4913 673 ----LEAELERLDASSDDL------------------AALEEQLE---ELEAELEELEEELDELKGEIGRLEKELEQAEE 727
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 654 TCEKLETLEQENSELEREnrkfkktldsfknltFQLESLEKENSQLDEENLElrrsveslkcASMRmAQLQLENKELESE 733
Cdd:COG4913 728 ELDELQDRLEAAEDLARL---------------ELRALLEERFAAALGDAVE----------RELR-ENLEERIDALRAR 781
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 734 KEQLRKGLELMRASFKKTERLEVSYQGLDTEN----QRLQKALENSN-----KKIQQL--ESELQDLEMENQTLQKSLEE 802
Cdd:COG4913 782 LNRAEEELERAMRAFNREWPAETADLDADLESlpeyLALLDRLEEDGlpeyeERFKELlnENSIEFVADLLSKLRRAIRE 861
|
650 660
....*....|....*....|
gi 1720363745 803 LKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 862 IK------ERIDPLNDSLKR 875
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
491-695 |
2.30e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 49.24 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 491 SKILKVEKENQRLNKKVEILENEI-IQEK----QSLQNCQNLSK--DLMKEKAQLEKTIETLRENSERQIKILEQENEHL 563
Cdd:PHA02562 174 DKIRELNQQIQTLDMKIDHIQQQIkTYNKnieeQRKKNGENIARkqNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 564 NQTVSSLRQrSQISAEARVKDIEKENKILHE---------SIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENEL 634
Cdd:PHA02562 254 SAALNKLNT-AAAKIKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEF 332
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 635 NHlgkenelLQKKITNLKitcEKLETLEQENSELERENRKFKKTL----DSFKNLTFQLESLEKE 695
Cdd:PHA02562 333 NE-------QSKKLLELK---NKISTNKQSLITLVDKAKKVKAAIeelqAEFVDNAEELAKLQDE 387
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
345-652 |
2.33e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.35 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELMEENmtlEMAQKQSMD 424
Cdd:pfam17380 300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKREL---ERIRQEEIA 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 425 ESLHLGWELEQISrtselAEAPQKS--LGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQR 502
Cdd:pfam17380 372 MEISRMRELERLQ-----MERQQKNerVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAR 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 503 lnkKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnqtvsslRQRSQISAEARV 582
Cdd:pfam17380 447 ---EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--------RKQAMIEEERKR 515
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 583 KDIEKENKILHESIKETcgKLSKIEFEKRQMKKELELYK---EKGERAEELENELNHLGKENELLQKKITNLK 652
Cdd:pfam17380 516 KLLEKEMEERQKAIYEE--ERRREAEEERRKQQEMEERRriqEQMRKATEERSRLEAMEREREMMRQIVESEK 586
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
2.53e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.67 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 657 KLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESLKcasmrmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 737 LRKgleLMRASFKK---TERLEV-----SYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissK 808
Cdd:COG3883 88 LGE---RARALYRSggsVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---A 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-982 |
3.00e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 3.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETCGKLSKIEFEKRQMKKELELYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 626 RAEELENELNHLGKENELLQkkitnlkitcEKLETLEQENSELERENrkFKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Cdd:COG4717 157 ELRELEEELEELEAELAELQ----------EELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 706 LRRSVESLKcasmRMAQLQLENKELESEKEQLR----------KGLELMRASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:COG4717 225 LEEELEQLE----NELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 776 NKKIQQLESELQDLEMENQTLQKSLEELKISskrleqlEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDttleen 855
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGLP-------PDLSPEELLELLDRIEELQELLREAEELEEELQLEE------ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 856 nvkignLEKENKTLFKEINVYKE----SCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHE 931
Cdd:COG4717 368 ------LEQEIAALLAEAGVEDEeelrAALEQAEEYQELKEELEELEEQLEELLGELEEL-LEALDEEELEEELEELEEE 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 932 LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEAR 982
Cdd:COG4717 441 LEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEE 491
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
641-940 |
3.13e-05 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 49.07 E-value: 3.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 641 NELLQKKITNLKIT----CEKLETLEQENSELERENRKFKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRRSVE 711
Cdd:PRK00448 4 QEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSIEVE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 712 SLKCasmrmaQLQLENKELESEKEQLRKGLELMRASFKKTE------RLEVSYQGlDTENQRL-QKALENSNKKIQQLES 784
Cdd:PRK00448 84 NITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEKFGF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 785 ELqdLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KDTTL 852
Cdd:PRK00448 157 GI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKEINE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 853 EENNVKI-GNL------EKENKTLFKEINV--YKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQQMN 922
Cdd:PRK00448 235 EERRVVVeGYVfkveikELKSGRHILTFKItdYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDLVMN 313
|
330
....*....|....*....
gi 1720363745 923 -NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 314 aQDINEIKHPERKDTAEEE 332
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1033-1211 |
3.74e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 3.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1033 ESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLQVENS 1112
Cdd:COG3883 24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE---IEERREELGERARALYRSGG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1113 T-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESIMKEREDLKSLYDALIKDHEKLELLHERQ 1170
Cdd:COG3883 101 SvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1720363745 1171 ASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQ 1211
Cdd:COG3883 181 EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
538-679 |
3.84e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 48.70 E-value: 3.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 538 LEKTIETLRENSERQIkilEQENEHLNQTVSSLRQRsqISA-EARVKDIEKENKILHESIKEtcgKLSKIEfekrQMKKE 616
Cdd:COG2433 382 LEELIEKELPEEEPEA---EREKEHEERELTEEEEE--IRRlEEQVERLEAEVEELEAELEE---KDERIE----RLERE 449
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 617 LELYKEKGERAEELENELNHLGKENELLQKkitnlkitceKLETLEQENSELERENRKFKKTL 679
Cdd:COG2433 450 LSEARSEERREIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKELW 502
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
495-852 |
3.86e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.80 E-value: 3.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 495 KVEKENQRLN----KKVEILENEII--QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERqikiLEQENEhlnqtVS 568
Cdd:PRK04863 301 QLAAEQYRLVemarELAELNEAESDleQDYQAASDHLNLVQTALRQQEKIERYQADLEELEER----LEEQNE-----VV 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 569 SLRQRSQISAEARVKDIEkenkilhESIKETCGKLSK-----IEFEKR--QMKKELELYkekgERAEELeNELNHLGKEN 641
Cdd:PRK04863 372 EEADEQQEENEARAEAAE-------EEVDELKSQLADyqqalDVQQTRaiQYQQAVQAL----ERAKQL-CGLPDLTADN 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 642 --ELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESlekenSQLDEENLELRRSVESLKCASMR 719
Cdd:PRK04863 440 aeDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSR-----SEAWDVARELLRRLREQRHLAEQ 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 720 MAQLQLENKELESEKEQLRKgLELMRASFKKteRLEVSYQG---LDTENQRLQKALENSN--------------KKIQQL 782
Cdd:PRK04863 515 LQQLRMRLSELEQRLRQQQR-AERLLAEFCK--RLGKNLDDedeLEQLQEELEARLESLSesvsearerrmalrQQLEQL 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 783 ESELQDLEM---ENQTLQKSLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:PRK04863 592 QARIQRLAArapAWLAAQDALARLReqsgeefedsqdVTEYMQQLLERE-RELTVERDELAARKQALDEEIERLSQPGGS 670
|
....*
gi 1720363745 848 KDTTL 852
Cdd:PRK04863 671 EDPRL 675
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
656-859 |
4.95e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.47 E-value: 4.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 656 EKLETLEQENSELERENRKFKKTLDSF------KNLTFQLESLEKENSQLDEENLELRRSVESLKcASMRMAQLQLEN-- 727
Cdd:COG3206 182 EQLPELRKELEEAEAALEEFRQKNGLVdlseeaKLLLQQLSELESQLAEARAELAEAEARLAALR-AQLGSGPDALPEll 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 728 -----KELESEKEQLRKGLELMRASFKKTERlevSYQGLDTENQRLQKALENSNKKI-QQLESELQDLEMENQTLQKSLE 801
Cdd:COG3206 261 qspviQQLRAQLAELEAELAELSARYTPNHP---DVIALRAQIAALRAQLQQEAQRIlASLEAELEALQAREASLQAQLA 337
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720363745 802 ELKISSKRLEQLEKENKSLEQEtsqLEKDKKQLEKENKRLrQQAEIkDTTLEENNVKI 859
Cdd:COG3206 338 QLEARLAELPELEAELRRLERE---VEVARELYESLLQRL-EEARL-AEALTVGNVRV 390
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
575-837 |
5.31e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.09 E-value: 5.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 575 QISAEARVKDIE---------KENKILHESIKETCGKLSKIEFEKRQMKKELELYKEkgeraeeLENELNHLGKEN-ELL 644
Cdd:PHA02562 146 QLSAPARRKLVEdlldisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNK-------NIEEQRKKNGENiARK 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 645 QKKITNLKitcEKLETLEQENSELERE----NRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCasmrM 720
Cdd:PHA02562 219 QNKYDELV---EEAKTIKAEIEELTDEllnlVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----T 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 721 AQLQLENKELESEKEQLRKGlelmrasfkkTERLEVSYQGLDTENQRLQKALENSnKKIQQLESelqDLEMENQTLQKSL 800
Cdd:PHA02562 292 QQISEGPDRITKIKDKLKEL----------QHSLEKLDTAIDELEEIMDEFNEQS-KKLLELKN---KISTNKQSLITLV 357
|
250 260 270
....*....|....*....|....*....|....*..
gi 1720363745 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:PHA02562 358 DKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
819-1158 |
6.59e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 47.81 E-value: 6.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL--------EENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKEN 890
Cdd:pfam05557 6 ESKARLSQLQNEKKQMELEHKRARIELEKKASALkrqldresDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 891 KELVKRATIDIKTLVTLREDLVSEK-----LKTQQMNNDLEKLTHELEKIGLNKErllHDEQSTDDSRYKLLESKLESTL 965
Cdd:pfam05557 86 EALNKKLNEKESQLADAREVISCLKnelseLRRQIQRAELELQSTNSELEELQER---LDLLKAKASEAEQLRQNLEKQQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 966 KKSLEiKEEKIAALEARLEESTNYNQqlrhELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVK 1045
Cdd:pfam05557 163 SSLAE-AEQRIKELEFEIQSQEQDSE----IVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1046 DRLIEVERNNATLQAEKQALKTQLKQLEtqnNNLQAQILALqRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELQSWV---KLAQDTGLNL-RSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKAR 313
|
330 340 350
....*....|....*....|....*....|...
gi 1720363745 1126 AQLLIQQSSLENENESIMKEREDLKSLYDALIK 1158
Cdd:pfam05557 314 RELEQELAQYLKKIEDLNKKLKRHKALVRRLQR 346
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
689-1073 |
7.05e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.58 E-value: 7.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 689 LESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSyqgLDTENQRL 768
Cdd:pfam07888 47 LQAQEAANRQREKEKERYKRDREQWE---RQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE---LSEEKDAL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 769 QKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:pfam07888 121 LAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEEELRSLSKEFQEL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 849 DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKL 928
Cdd:pfam07888 198 RNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 929 THELEKIGLNkerllhdeqsTDDSRYKLLE-----SKLESTLKKSLEIKEEKIAALEARLEestnynqqlrhelktvkkn 1003
Cdd:pfam07888 278 RLQAAQLTLQ----------LADASLALREgrarwAQERETLQQSAEADKDRIEKLSAELQ------------------- 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 1004 yeALKQRQDEERM--VQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:pfam07888 329 --RLEERLQEERMerEKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
8.71e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 46.39 E-value: 8.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLFKEINVYKescvRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 1720363745 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-713 |
9.11e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 9.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 498 KENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKILEQENEHLNQTVSSLRQRsqis 577
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKE---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 578 AEARVKDIEKENKILHESIKE--TCGKLSKIEF-----EKRQMKKELELYK----EKGERAEELENELNHLGKENELLQK 646
Cdd:COG4942 92 IAELRAELEAQKEELAELLRAlyRLGRQPPLALllspeDFLDAVRRLQYLKylapARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 647 KITNLKitcEKLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESL 713
Cdd:COG4942 172 ERAELE---ALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARL 232
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
685-1132 |
9.66e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 47.43 E-value: 9.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 685 LTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLE-NKELESEKEQLRKGLELMRASFKKT-ERLEVSYQGLD 762
Cdd:pfam05557 7 SKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDrNQELQKRIRLLEKREAEAEEALREQaELNRLKKKYLE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 763 TENQRLQ-----------------KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:pfam05557 87 ALNKKLNekesqladarevisclkNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEEnNVKIGNLEKENKTLFKEINVYKEScvrlkeleKENKELVKRATIDIKTLV 905
Cdd:pfam05557 167 EAEQRIKELEFEIQSQEQDSEIVKNSKSE-LARIPELEKELERLREHNKHLNEN--------IENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 906 TLREDLVSEKLKTQQMNNDLEKLTHELEKIG--------------------LNKERLLHDEQSTDDSRYKLLEsKLESTL 965
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELQSWVKLAqdtglnlrspedlsrrieqlQQREIVLKEENSSLTSSARQLE-KARREL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 966 KKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEermVQSSIPVSGEDDKWGRESQEATRELLKVK 1045
Cdd:pfam05557 317 EQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILES---YDKELTMSNYSPQLLERIEEAEDMTQKMQ 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1046 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Cdd:pfam05557 394 AHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQ--ESLADPSYSKEEVDSLRRKLETLELERQRLREQKNELEMEL 471
|
....*..
gi 1720363745 1126 AQLLIQQ 1132
Cdd:pfam05557 472 ERRCLQG 478
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-926 |
1.00e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.23 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 729 ELESEKEQLRKGLELMRASFKKT-----ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVKIGNLEKEN---- 866
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELKKLgfer 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 867 ------KTLFKEINVYKEscvRLKELEKE----NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK05771 205 leleeeGTPSELIREIKE---ELEEIEKEreslLEELKELAKKYLEELLALYEYLEIELERAEALSKFLK 271
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
394-690 |
1.03e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.23 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 394 MEMERD----MDRKK---IEELMEENMtLEMAQKQSMDESLHLGWELEQISRTSELAEapqkSLGHEVNELTSSKLLKLE 466
Cdd:PRK05771 4 VRMKKVlivtLKSYKdevLEALHELGV-VHIEDLKEELSNERLRKLRSLLTKLSEALD----KLRSYLPKLNPLREEKKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 467 MENQSLtktvEELRSTADSAAGstskilKVEKENQRLNKKVEILENEI---IQEKQSLQNCQNLSKDLmkEKAQLEKTIE 543
Cdd:PRK05771 79 VSVKSL----EELIKDVEEELE------KIEKEIKELEEEISELENEIkelEQEIERLEPWGNFDLDL--SLLLGFKYVS 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 544 ----TLRENSERQIKILEQENEHLnqTVSSLRQRSQISAEARVKDIEKENKILhesiketcgklSKIEFEKRQMKKE--- 616
Cdd:PRK05771 147 vfvgTVPEDKLEELKLESDVENVE--YISTDKGYVYVVVVVLKELSDEVEEEL-----------KKLGFERLELEEEgtp 213
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 617 LELYKEKGERAEELENELNHLGKE-NELLQKKITNLKITCEKLETLEQENSELErenrKFKKTldsfkNLTFQLE 690
Cdd:PRK05771 214 SELIREIKEELEEIEKERESLLEElKELAKKYLEELLALYEYLEIELERAEALS----KFLKT-----DKTFAIE 279
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
704-1222 |
1.04e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 704 LELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTErlevsYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:COG4913 245 EDAREQIELLE----PIRELAERYAAARERLAELEYLRAALRLWFAQRR-----LELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 784 SELQDLEMENQTLQKS--------LEELKissKRLEQLEKENKSLEQETSQLEK-----------DKKQLEKENKRLRQQ 844
Cdd:COG4913 316 ARLDALREELDELEAQirgnggdrLEQLE---REIERLERELEERERRRARLEAllaalglplpaSAEEFAALRAEAAAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 845 AEIKDTTLEENNVKIGNLEKENKTLFKEinvykescvrLKELEKENKELVKRA-TIDiKTLVTLREDLVSE-KLKTQQMN 922
Cdd:COG4913 393 LEALEEELEALEEALAEAEAALRDLRRE----------LRELEAEIASLERRKsNIP-ARLLALRDALAEAlGLDEAELP 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 923 ----------------------------------NDLEKLTHELEKIGLnKERLLHDEQSTDDSRYKLLESKLESTLKKs 968
Cdd:COG4913 462 fvgelievrpeeerwrgaiervlggfaltllvppEHYAAALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGK- 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 969 LEIKEEKIAA-LEARLEESTNY-----NQQLRHELK------TVKKNYEAL-KQRQDEERmvqsSIPVSGEDdkwgresq 1035
Cdd:COG4913 540 LDFKPHPFRAwLEAELGRRFDYvcvdsPEELRRHPRaitragQVKGNGTRHeKDDRRRIR----SRYVLGFD-------- 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1036 eaTRELLKVKDRLIevernnATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqvenstln 1115
Cdd:COG4913 608 --NRAKLAALEAEL------AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE---------- 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1116 sqstslmnqnaqllIQQssLENENESIMKEREDLKSLYDALikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH 1195
Cdd:COG4913 670 --------------IAE--LEAELERLDASSDDLAALEEQL----EELEAELEELEEELDELKGEIGRLEKELEQAEEEL 729
|
570 580
....*....|....*....|....*....
gi 1720363745 1196 KDLEDRYNQL--LKQKGQLEDLEKMIKTE 1222
Cdd:COG4913 730 DELQDRLEAAedLARLELRALLEERFAAA 758
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
1.14e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 44.92 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 719 RMAQLQLENKELESEKEQLRKGLELMRASfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 799 SLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKenktlfkeinvyke 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQDLQDELVALQLQLNMAEE-------------- 148
|
170
....*....|....*...
gi 1720363745 879 scvRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
1.17e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.75 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRVDKL 325
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReELGERARALYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 326 E-----SELSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKENLQLKAKLH 392
Cdd:COG3883 106 DvllgsESFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQQAEQEALLA 185
|
170 180 190
....*....|....*....|....*....|
gi 1720363745 393 DMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
979-1213 |
1.18e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 979 LEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddkwgreSQEATRELLKVKDRLIEvernnatL 1058
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEE-------AKLLLQQLSELESQLAE-------A 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1138
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 1139 NESIMkerEDLKSLYDALIKDHEKLEllheRQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLE 1213
Cdd:COG3206 311 AQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-383 |
1.33e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.00 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 262 RLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmNLLSDARSARmYRDELDALREkavrvdKLESELSRYKERLHDIEf 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEE------ELEALKARWEAEKELIE- 471
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1720363745 342 ykaRVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:COG0542 472 ---EIQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE 510
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
957-1120 |
1.48e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 957 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDE--ERMVQSSIPVSGED------- 1027
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRALYRSGGSVSYLDvllgses 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1028 --------DKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:COG3883 114 fsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAA 193
|
170 180
....*....|....*....|.
gi 1720363745 1100 LQTQNAKLQVENSTLNSQSTS 1120
Cdd:COG3883 194 AEAQLAELEAELAAAEAAAAA 214
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
622-714 |
1.62e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 46.39 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 622 EKGERAEELENELNHLGKENELLQKKITNLKITCEKLET-LEQENSELERENRKFKKtldsFKNLTFQLESLEKENSQLD 700
Cdd:COG2433 410 EEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLEReLSEARSEERREIRKDRE----ISRLDREIERLERELEEER 485
|
90
....*....|....
gi 1720363745 701 EENLELRRSVESLK 714
Cdd:COG2433 486 ERIEELKRKLERLK 499
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-642 |
1.73e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 46.82 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 321 RVDKLESELSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELAEAPQKSLGHEVNELTSskllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 478 ELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIETLRENSERQIKIL 556
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVEnLQDLLDRATNQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 557 EQeNEHLNQTVSSLRQRsqiSAEARVKDIEKEN-KILHESIKETCGKLSKIEFEkrqMKKELELYKEKgerAEELENELN 635
Cdd:PLN02939 324 DQ-NQDLRDKVDKLEAS---LKEANVSKFSSYKvELLQQKLKLLEERLQASDHE---IHSYIQLYQES---IKEFQDTLS 393
|
....*..
gi 1720363745 636 HLGKENE 642
Cdd:PLN02939 394 KLKEESK 400
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
1.84e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720363745 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINvykescVRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD------EELAELEAELEELEAE 164
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
1.87e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 571 RQRSQISAE-ARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKE-----LELYKEKGERAEELENELNHLGKENELL 644
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADEtladrLEELREELDAAQEAQAFIQQHGKALAQL 922
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 645 QKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENS-QLDEENLELrrsVESLKcasmrmAQL 723
Cdd:COG3096 923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAvGLLGENSDL---NEKLR------ARL 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 724 qlenKELESEKEQLRkglelmrasfkktERLEVSYQGLDTENQRLQK---ALENSNKKIQQLESELQDL------EMENQ 794
Cdd:COG3096 994 ----EQAEEARREAR-------------EQLRQAQAQYSQYNQVLASlksSRDAKQQTLQELEQELEELgvqadaEAEER 1056
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1720363745 795 TLQKSLE---ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1057 ARIRRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
1.91e-04 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 43.45 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLEselQDLEMENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 1720363745 799 SLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
768-872 |
2.00e-04 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 45.49 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 768 LQKALENSNKKIQQLESELQDLEMENQTLQksleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEi 847
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENEELE----------SELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFE- 201
|
90 100
....*....|....*....|....*
gi 1720363745 848 kdTTLEENNVKIGNLEKENKTLFKE 872
Cdd:COG4026 202 --ELLKKRLLEVFSLEELWKELFPE 224
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-869 |
2.15e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 46.23 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 779 IQQLESELQDLEMENQTLQKslEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|.
gi 1720363745 859 IGNLEKENKTL 869
Cdd:COG0542 487 IPELEKELAEL 497
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-671 |
2.35e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 464 KLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLqncqnlsKDLMKEKAQLEKTIE 543
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL-------AELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEAR---VKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE-L 619
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEaL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 620 YKEKGERAEELENELNhlgKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:COG4942 180 LAELEEERAALEALKA---ERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-573 |
2.38e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.49 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 320 VRVDKLEselsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 480 RSTAD----SAAGSTSKILKVEKENQR-LNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:PRK04863 483 RKIAGevsrSEAWDVARELLRRLREQRhLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEE 562
|
330
....*....|....*....
gi 1720363745 555 iLEQENEHLNQTVSSLRQR 573
Cdd:PRK04863 563 -LEARLESLSESVSEARER 580
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1073 |
3.13e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 45.28 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 734 KEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLemeNQTLQKSLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLK--ELEKENK 891
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSeaEAEQALD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI 971
Cdd:COG4372 187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 972 KEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEV 1051
Cdd:COG4372 267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLL 346
|
330 340
....*....|....*....|..
gi 1720363745 1052 ERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG4372 347 LVGLLDNDVLELLSKGAEAGVA 368
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
716-878 |
3.19e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 716 ASMRMAQLQLENKELESEKEQLRKglelmrasfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQT 795
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQA----------ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 796 LQKSLEEL----------------------------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:COG3883 84 RREELGERaralyrsggsvsyldvllgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1720363745 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKE 878
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEA 203
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
531-844 |
3.19e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 45.60 E-value: 3.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 531 LMKEKAQLEKTIETLRENSERQIKILEQenehLNQTVSSLRQRSQISAEARV------KDIEKENKILHESIKETCGKLS 604
Cdd:PRK04778 100 FRKAKHEINEIESLLDLIEEDIEQILEE----LQELLESEEKNREEVEQLKDlyrelrKSLLANRFSFGPALDELEKQLE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 605 KIEfEKRQMKKELelyKEKGERAE------ELENELNHLGKENELLQKKITNLKITC-EKLETLEQENSELERENRKFKK 677
Cdd:PRK04778 176 NLE-EEFSQFVEL---TESGDYVEareildQLEEELAALEQIMEEIPELLKELQTELpDQLQELKAGYRELVEEGYHLDH 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 678 tldsfKNLTFQLESLEKENSQLDE--ENLELRRSVESLKCASMRMAQL--QLEN-----KELESEKEQLRKGLELMRASF 748
Cdd:PRK04778 252 -----LDIEKEIQDLKEQIDENLAllEELDLDEAEEKNEEIQERIDQLydILERevkarKYVEKNSDTLPDFLEHAKEQN 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 749 K----KTERLEVSYQgLDTENQRLQKALEnsnKKIQQLESELQDL--EMENQTLQKSL--EELKISSKRLEQLEKENKSL 820
Cdd:PRK04778 327 KelkeEIDRVKQSYT-LNESELESVRQLE---KQLESLEKQYDEIteRIAEQEIAYSElqEELEEILKQLEEIEKEQEKL 402
|
330 340
....*....|....*....|....
gi 1720363745 821 EQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK04778 403 SEMLQGLRKDELEAREKLERYRNK 426
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-714 |
4.03e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 4.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 580 ARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEK------------GERAEELENELNHLGKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 648 ITNLKITCEKLE-TLEQENSELERENRKFKKTLDSFKNLTFQLE----SLEKENSQLDEENLELRRSVESLK 714
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLE 432
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
251-408 |
4.40e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 4.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 251 VELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSA-RMYRDELDALREKAVRVDKLESEL 329
Cdd:COG1579 10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTE----LEDLEKEiKRLELEIEEVEARIKKYEEQLGNV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 330 SRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKLHDMEMERDMDRKKI 405
Cdd:COG1579 86 RNNKEYealQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAELEELEAER 165
|
...
gi 1720363745 406 EEL 408
Cdd:COG1579 166 EEL 168
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
252-686 |
4.63e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 4.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDarsarmyrdeldaLREKAVRVDKLESELSR 331
Cdd:TIGR04523 315 ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE-------------LEEKQNEIEKLKKENQS 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 332 YKERLHDIEFYKARVEelkednqvlletkTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR04523 382 YKQEIKNLESQINDLE-------------SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTsSKLLKLEMENQSLTKTVEELRSTADSaagSTS 491
Cdd:TIGR04523 449 DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKE-KELKKLNEEKKELEEKVKDLTKKISS---LKE 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 492 KILKVEKENQRLNKKVEILENEIIQEKQSLQNCQnlskdLMKEKAQLEKTIETLRE--------NSERQIKILEQENEHL 563
Cdd:TIGR04523 525 KIEKLESEKKEKESKISDLEDELNKDDFELKKEN-----LEKEIDEKNKEIEELKQtqkslkkkQEEKQELIDQKEKEKK 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 564 NQTVSSLRQRSQISA-EARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKE-- 640
Cdd:TIGR04523 600 DLIKEIEEKEKKISSlEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDii 679
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 641 -------NELL---QKKITNlKITCEKLETLEQENSELERENRKFKKTLDSFKNLT 686
Cdd:TIGR04523 680 elmkdwlKELSlhyKKYITR-MIRIKDLPKLEEKYKEIEKELKKLDEFSKELENII 734
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
974-1176 |
4.82e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 4.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 974 EKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQ--RQDEERMVQSSipvsgeddkwgRESQEATRELLKVKDRLIEV 1051
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlAALERRIAALA-----------RRIRALEQELAALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1052 ERNNATLQAEKQALKTQLKQ--------------------------------LETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:COG4942 89 EKEIAELRAELEAQKEELAEllralyrlgrqpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 1100 LQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYES 1176
Cdd:COG4942 169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
728-1365 |
5.37e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 5.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 728 KELESEKEQLRKgLELMRASFKKTERLEVSYQGLDTENQRL-----QKALENSNKKIQQLESELQDLEMENQTLQKSLEE 802
Cdd:COG4913 242 EALEDAREQIEL-LEPIRELAERYAAARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 803 LKISSKRLEQLEKENKSleQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEInvyKESCVR 882
Cdd:COG4913 321 LREELDELEAQIRGNGG--DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA---AALLEA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 883 LKELEKENKELVKRATIDIKTLVTLREDLVSEK--LKTQQMNND--LEKLTHEL-EKIGLNK------------------ 939
Cdd:COG4913 396 LEEELEALEEALAEAEAALRDLRRELRELEAEIasLERRKSNIParLLALRDALaEALGLDEaelpfvgelievrpeeer 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 940 -----ERLLHDEQST---DDSRYKLLESKLESTlKKSLEIKEEKIAALEARLEESTNYNQQLRHELkTVKKN--YEALKQ 1009
Cdd:COG4913 476 wrgaiERVLGGFALTllvPPEHYAAALRWVNRL-HLRGRLVYERVRTGLPDPERPRLDPDSLAGKL-DFKPHpfRAWLEA 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1010 RQDEERMVqssIPVSGEDDkWGRESQEATRELLkVKdrlieverNNATLQaEKQALKTQLKQLETQNNNlQAQILALQRQ 1089
Cdd:COG4913 554 ELGRRFDY---VCVDSPEE-LRRHPRAITRAGQ-VK--------GNGTRH-EKDDRRRIRSRYVLGFDN-RAKLAALEAE 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1090 TVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLhER 1169
Cdd:COG4913 619 LAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAAL-EE 692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1170 QASEyesliskhgtlksahknLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDR 1249
Cdd:COG4913 693 QLEE-----------------LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1250 LNYTYSQLLKE-TEILQMDHKNLKSVLNNsklEQTRLEAEFSKLKEQY----QQLDITSTKLNNQCELLSQLKGN-LEEE 1323
Cdd:COG4913 756 AAALGDAVERElRENLEERIDALRARLNR---AEEELERAMRAFNREWpaetADLDADLESLPEYLALLDRLEEDgLPEY 832
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 1720363745 1324 NRHLLDQIQTLMLQNRTLLEQNMESkDLFHVEQRqyIDKLNE 1365
Cdd:COG4913 833 EERFKELLNENSIEFVADLLSKLRR-AIREIKER--IDPLND 871
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
6.31e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.36 E-value: 6.31e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1720363745 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
960-1170 |
6.98e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 44.66 E-value: 6.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 960 KLESTLKKSLEIKEEKIAALEARLEeSTNYNQQLrheLKTVKKNYEA---LKQRQDEERMVQSSIpvsgedDKWGRESQE 1036
Cdd:PRK10929 79 KLSAELRQQLNNERDEPRSVPPNMS-TDALEQEI---LQVSSQLLEKsrqAQQEQDRAREISDSL------SQLPQQQTE 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1037 ATRELLKVKDRL--------IEVERNNATLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqt 1102
Cdd:PRK10929 149 ARRQLNEIERRLqtlgtpntPLAQAQLTALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL-- 220
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 1103 qNAKLQVENSTLNSQStslmNQNAQLLIQQSSLENEN-----ESIMKEREDLKSLYDALIKDHEKLELLHERQ 1170
Cdd:PRK10929 221 -DAYLQALRNQLNSQR----QREAERALESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-867 |
7.45e-04 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 41.23 E-value: 7.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 777 KKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|.
gi 1720363745 857 VKIGNLEKENK 867
Cdd:pfam04871 81 LLLGDLEEKVE 91
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
246-391 |
7.57e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.99 E-value: 7.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQ---ENMNLLSDARSARMYRD---ELDALREka 319
Cdd:COG1579 26 LKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEArikKYEEQLGNVRNNKEYEAlqkEIESLKR-- 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 320 vRVDKLESELSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDK-LHELEKENLQLKAKL 391
Cdd:COG1579 104 -RISDLEDEILELMER---IEELEEELAELEAELAELEAELEEKKAELDEELAELEAeLEELEAEREELAAKI 172
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1036-1114 |
7.94e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 42.23 E-value: 7.94e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
247-408 |
8.06e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 8.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSAR------MYRDELDALREKAV 320
Cdd:COG4913 688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELralleeRFAAALGDAVEREL 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 321 RvDKLESELSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDqLEGTRAR-----SDKLHELEKENLQLKAK--- 390
Cdd:COG4913 768 R-ENLEERIDALRARLNRAEeeLERAMRAFNREWPAETADLDADLES-LPEYLALldrleEDGLPEYEERFKELLNEnsi 845
|
170 180
....*....|....*....|....
gi 1720363745 391 ------LHDMEMERDMDRKKIEEL 408
Cdd:COG4913 846 efvadlLSKLRRAIREIKERIDPL 869
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
752-1020 |
9.12e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 9.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 752 ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSlEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:COG3206 164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLS-EEAKLLLQQLSELESQLAEARAELAEAEARL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 832 KQLEKENKRLRQQAeikdtTLEENNVKIGNLEKenktlfkeinvykescvRLKELEKENKELVKRATIDIKTLVTLRedl 911
Cdd:COG3206 243 AALRAQLGSGPDAL-----PELLQSPVIQQLRA-----------------QLAELEAELAELSARYTPNHPDVIALR--- 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 912 vseklktQQMNNDLEKLTHELEKIGLNKErllhdeqstddSRYKLLESKLEStLKKSLEIKEEKIAALEARLEEStnynQ 991
Cdd:COG3206 298 -------AQIAALRAQLQQEAQRILASLE-----------AELEALQAREAS-LQAQLAQLEARLAELPELEAEL----R 354
|
250 260
....*....|....*....|....*....
gi 1720363745 992 QLRHELKTVKKNYEALKQRQDEERMVQSS 1020
Cdd:COG3206 355 RLEREVEVARELYESLLQRLEEARLAEAL 383
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-896 |
1.01e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.00 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 706 LRRSVESLKCASMR-MAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLL---QKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 785 ELQDLEmenqtlqksleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-IKDTTLEE-NNVKIGNL 862
Cdd:PRK12704 101 KLELLE-----------------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErISGLTAEEaKEILLEKV 163
|
170 180 190
....*....|....*....|....*....|....
gi 1720363745 863 EKENKTlfkeinvykESCVRLKELEKENKELVKR 896
Cdd:PRK12704 164 EEEARH---------EAAVLIKEIEEEAKEEADK 188
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
535-846 |
1.02e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.18 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 535 KAQLEKTIETLRENSERQIKiLEQENEHLNQTVSS-----------------LRQRSQISAE-ARVKDIEKENKILHESI 596
Cdd:PRK04863 792 RAEREELAERYATLSFDVQK-LQRLHQAFSRFIGShlavafeadpeaelrqlNRRRVELERAlADHESQEQQQRSQLEQA 870
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 597 KETCGKLSKIE-----FEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:PRK04863 871 KEGLSALNRLLprlnlLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT 950
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 672 NRKFKKTLDSFKNLTFQLESLEKENSQ-LDEENLELrrsVESLKcasmrmAQLqlenKELESEKEQLRKGLELMRASFkk 750
Cdd:PRK04863 951 QRDAKQQAFALTEVVQRRAHFSYEDAAeMLAKNSDL---NEKLR------QRL----EQAEQERTRAREQLRQAQAQL-- 1015
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 751 TERLEVsYQGLDTENQRLQKALensnkkiQQLESELQDL------EMENQTLQKSLE---ELKISSKRLEQLEKENKSLE 821
Cdd:PRK04863 1016 AQYNQV-LASLKSSYDAKRQML-------QELKQELQDLgvpadsGAEERARARRDElhaRLSANRSRRNQLEKQLTFCE 1087
|
330 340
....*....|....*....|....*
gi 1720363745 822 QETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK04863 1088 AEMDNLTKKLRKLERDYHEMREQVV 1112
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1036-1377 |
1.04e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1036 EATRE-LLKVKDRLIEVERNNATLQaeKQALKTQ-LKQLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST 1113
Cdd:TIGR02168 182 ERTREnLDRLEDILNELERQLKSLE--RQAEKAErYKELKAELRELELALLVLRLE--ELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1114 LNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALikdHEKLELLHERQaseyesliskhgtlksahKNLEV 1193
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL---EQQKQILRERL------------------ANLER 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1194 EHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEkMLLESKNhevvaseykklcgendrlnytysQLLKETEILQMDHKNLKS 1273
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLE-ELKEELE-----------------------SLEAELEELEAELEELES 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1274 VLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQ--NRTLLEQNMESKDL 1351
Cdd:TIGR02168 373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEEL 452
|
330 340
....*....|....*....|....*.
gi 1720363745 1352 FHvEQRQYIDKLNELRRQKEKLEEKI 1377
Cdd:TIGR02168 453 QE-ELERLEEALEELREELEEAEQAL 477
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
473-1164 |
1.06e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 473 TKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKD-------LMKEKAQLEKTIETL 545
Cdd:pfam01576 1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEaeemrarLAARKQELEEILHEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 546 R---ENSERQIKILEQENEHLNQTVSSL----------RQRSQI---SAEARVKDIEKENKILHEsiketcgKLSKIEFE 609
Cdd:pfam01576 81 EsrlEEEEERSQQLQNEKKKMQQHIQDLeeqldeeeaaRQKLQLekvTTEAKIKKLEEDILLLED-------QNSKLSKE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 610 KRQMKKELELYKEKGERAEELENELNHLGKENELLqkkITNLKitcEKLETLEQENSELERENRKFKKTL----DSFKNL 685
Cdd:pfam01576 154 RKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAM---ISDLE---ERLKKEEKGRQELEKAKRKLEGEStdlqEQIAEL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 686 TFQLESLEKENSQLDEenlELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEvsyQGLDTEN 765
Cdd:pfam01576 228 QAQIAELRAQLAKKEE---ELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQR---RDLGEEL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 766 QRLQKALENS-----------NKKIQQLESELQDLEMENQTLQKSLEELKIssKRLEQLEKENKSLEQE---TSQLEKDK 831
Cdd:pfam01576 302 EALKTELEDTldttaaqqelrSKREQEVTELKKALEEETRSHEAQLQEMRQ--KHTQALEELTEQLEQAkrnKANLEKAK 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 832 KQLEKENKRLrqQAEIKdttleenNVKIGNLEKENKTLFKEINVyKESCVRLKELEKENKELVKRATidiktlvtlreDL 911
Cdd:pfam01576 380 QALESENAEL--QAELR-------TLQQAKQDSEHKRKKLEGQL-QELQARLSESERQRAELAEKLS-----------KL 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQStddsrykLLESKLESTLKKSLEIK--EEKIAALEARLEESTNY 989
Cdd:pfam01576 439 QSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE-------LLQEETRQKLNLSTRLRqlEDERNSLQEQLEEEEEA 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 990 NQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQL 1069
Cdd:pfam01576 512 KRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK--RLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDL 589
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1070 KQLETQNNNLQAQilalQRQTVSLQEQNTTLQTQNA----KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKE 1145
Cdd:pfam01576 590 DHQRQLVSNLEKK----QKKFDQMLAEEKAISARYAeerdRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAE 665
|
730
....*....|....*....
gi 1720363745 1146 REDLKSLYDALIKDHEKLE 1164
Cdd:pfam01576 666 MEDLVSSKDDVGKNVHELE 684
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
528-858 |
1.12e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.79 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA----EARVKDIEKENKILHESIKETCGKL 603
Cdd:COG5185 273 NAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAeqelEESKRETETGIQNLTAEIEQGQESL 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 604 SKIEFEKRQMKKELELYKEKGERAEELENELNHL-GKENELLQKKITNLKITCEKLETLEQENSELERENrkfkktldsf 682
Cdd:COG5185 353 TENLEAIKEEIENIVGEVELSKSSEELDSFKDTIeSTKESLDEIPQNQRGYAQEILATLEDTLKAADRQI---------- 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 683 KNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLD 762
Cdd:COG5185 423 EELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLE 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 763 TENQRLQKALENSNKKIQQLESELQDLEMENQTLQKsleelkisskrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Cdd:COG5185 503 KLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHI------------LALENLIPASELIQASNAKTDGQAANLRTAVI 570
|
330
....*....|....*.
gi 1720363745 843 QQAEIKDTTLEENNVK 858
Cdd:COG5185 571 DELTQYLSTIESQQAR 586
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
1.13e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 43.54 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 566 TVSSLRQRSQISAEARvkDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKgeraEELENELNHLGKENELLQ 645
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRER----EELQREEERLVQKEEQLD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 646 KKitnlkitCEKLETLEQENSELEREnrkfkktldsfknLTFQLESLEKENSQLDEENLElrrsVESLKCASMRMAQLQL 725
Cdd:PRK12705 95 AR-------AEKLDNLENQLEEREKA-------------LSARELELEELEKQLDNELYR----VAGLTPEQARKLLLKL 150
|
170
....*....|....*..
gi 1720363745 726 ENKELESEKEQLRKGLE 742
Cdd:PRK12705 151 LDAELEEEKAQRVKKIE 167
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
678-894 |
1.26e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 43.75 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLEN---KELESEKEQLRKGLELMRASFKKTERL 754
Cdd:PRK11281 71 LLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTlslRQLESRLAQTLDQLQNAQNDLAEYNSQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 755 EVSYQgldTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSleelkisskRLEQLEKENKSLEQETSQlekdKKQL 834
Cdd:PRK11281 151 LVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPS---------QRVLLQAEQALLNAQNDL----QRKS 214
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 835 EKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLFKEINVYkescvRLKELEKENKELV 894
Cdd:PRK11281 215 LEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQEAINSK-----RLTLSEKTVQEAQ 266
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
1.39e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.69 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 1720363745 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
257-586 |
1.39e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 257 KAKIRRLRQELEEKTEQlLDCKQELEQIEvelkRLQQENMNllsdaRSARMYRDELDALREKavrvdklESELSRYKERL 336
Cdd:pfam17380 295 KMEQERLRQEKEEKARE-VERRRKLEEAE----KARQAEMD-----RQAAIYAEQERMAMER-------ERELERIRQEE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 337 HDIEFYKARVEELKednqvlLETKTMLEdqLEGTRARSDKLHELEKENLQLKAKLHDMEMERdmdRKKIEELMEENMTLE 416
Cdd:pfam17380 358 RKRELERIRQEEIA------MEISRMRE--LERLQMERQQKNERVRQELEAARKVKILEEER---QRKIQQQKVEMEQIR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 417 MAQKQSMDESLHL-----GWELEQIsRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSlTKTVEELRSTADSAAGSTS 491
Cdd:pfam17380 427 AEQEEARQREVRRleeerAREMERV-RLEEQERQQQVERLRQQEEERKRKKLELEKEKRD-RKRAEEQRRKILEKELEER 504
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 492 KILKVEKENQR--LNKKVEILENEIIQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSERqIKILEQENEHLNQTVS 568
Cdd:pfam17380 505 KQAMIEEERKRklLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVE 583
|
330
....*....|....*...
gi 1720363745 569 SLRQRSQISAEARVKDIE 586
Cdd:pfam17380 584 SEKARAEYEATTPITTIK 601
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
529-1225 |
1.42e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.79 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 529 KDLMKEKAQLEKTIETLRENSERQiKILEQE----NEHLNQTVSSLRQRSQI--------SAEARVKDIEKENKILHESI 596
Cdd:COG3096 299 RQLAEEQYRLVEMARELEELSARE-SDLEQDyqaaSDHLNLVQTALRQQEKIeryqedleELTERLEEQEEVVEEAAEQL 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 597 KETCGKLSKIEFEKRQMKKELELYK----EKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELEREN 672
Cdd:COG3096 378 AEAEARLEAAEEEVDSLKSQLADYQqaldVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEV 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 673 RKFKKTLDSFKNLTFQ----LESLEK-----ENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLEL 743
Cdd:COG3096 458 LELEQKLSVADAARRQfekaYELVCKiagevERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERL 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 744 MRASFKKT-------ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTL----------QKSLEELK-- 804
Cdd:COG3096 538 LEEFCQRIgqqldaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELaarapawlaaQDALERLReq 617
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 805 ----------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLeennvkIGNLEKENKTLFKE-- 872
Cdd:COG3096 618 sgealadsqeVTAAMQQLLERE-REATVERDELAARKQALESQIERLSQPGGAEDPRL------LALAERLGGVLLSEiy 690
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 873 ---------------------INVYKESCVR--LKELEK--ENKELVKR--ATIDIKTLVTLR-EDLVSEKLKTQQM--- 921
Cdd:COG3096 691 ddvtledapyfsalygparhaIVVPDLSAVKeqLAGLEDcpEDLYLIEGdpDSFDDSVFDAEElEDAVVVKLSDRQWrys 770
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 922 -------------NNDLEKLTHELEKIGlnkERllHDEQSTDDSRYKLLESKLESTLKKSLEI-----KEEKIAALEARL 983
Cdd:COG3096 771 rfpevplfgraarEKRLEELRAERDELA---EQ--YAKASFDVQKLQRLHQAFSQFVGGHLAVafapdPEAELAALRQRR 845
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 984 EESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGR---------ESQEATRELLKVKDRLIEVERN 1054
Cdd:COG3096 846 SELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETLADRleelreeldAAQEAQAFIQQHGKALAQLEPL 925
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1055 NATLQAEKQ---ALKTQLKQLETQNNNLQAQILAL----QRQT-------VSLQEQNTTLQTQ-NAKLQVENSTLNSQST 1119
Cdd:COG3096 926 VAVLQSDPEqfeQLQADYLQAKEQQRRLKQQIFALsevvQRRPhfsyedaVGLLGENSDLNEKlRARLEQAEEARREARE 1005
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1120 SLMNQNAQLliqqsslenenESIMKEREDLKSLYDAliKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLE 1199
Cdd:COG3096 1006 QLRQAQAQY-----------SQYNQVLASLKSSRDA--KQQTLQELEQELEELGVQADAEAEERARIRRDELHEELSQNR 1072
|
810 820 830
....*....|....*....|....*....|
gi 1720363745 1200 DRYNQLLKQKG----QLEDLEKMIKTEQEK 1225
Cdd:COG3096 1073 SRRSQLEKQLTrceaEMDSLQKRLRKAERD 1102
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
602-887 |
1.48e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 42.88 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 602 KLSKIEFEKRQMKKELELYKEKgeraeELENELNHLGKENELLQKKITNLKitcekletleqenSELERENRKFKKTLDS 681
Cdd:pfam15905 55 KVKSLELKKKSQKNLKESKDQK-----ELEKEIRALVQERGEQDKRLQALE-------------EELEKVEAKLNAAVRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 682 FKNLTFQLESLEKENSQLDEENlELRRSVESLKCASMRMAQLQLENKELESEKEqlrkglelmrasfKKTERLEVSYQGL 761
Cdd:pfam15905 117 KTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLE-------------AKMKEVMAKQEGM 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 762 DTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:pfam15905 183 EGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESL 262
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1720363745 842 RQQAEIKDTTLEEN----NVKIGNLEKENKTLFKEINVYKEScvRLKELE 887
Cdd:pfam15905 263 KQSLEEKEQELSKQikdlNEKCKLLESEKEELLREYEEKEQT--LNAELE 310
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
1.62e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 42.90 E-value: 1.62e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 792 ENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
537-698 |
1.66e-03 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 43.14 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK----ENKILHESIKETCGKLSKIEFEKRQ 612
Cdd:COG5244 116 RLEETIEALKSTEKEEIVELRRENEELDKINLSLRERISSEEPELNKDGSKlsydELKEFVEESRVQVYDMVELVSDISE 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 613 MKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLE----TLEQENSELERENRKFKKTLDSFKNLTFQ 688
Cdd:COG5244 196 TLNRNGSIQRSSVRECERSNIHDVLFLVNGILDGVIDELNGELERLRrqlvSLMSSHGIEVEENSRLKATLEKFQSLELK 275
|
170
....*....|
gi 1720363745 689 LESLEKENSQ 698
Cdd:COG5244 276 VNTLQEELYQ 285
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
992-1201 |
1.77e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 992 QLRHELKTVKKNYEALKQ-RQDEERMVQSSIPVSG-EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQL 1069
Cdd:COG4913 239 RAHEALEDAREQIELLEPiRELAERYAAARERLAElEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1070 KQLETQNNNLQAQILALQRQTVslqeqnTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLliqqssleneNESIMKEREDL 1149
Cdd:COG4913 319 DALREELDELEAQIRGNGGDRL------EQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEF 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1720363745 1150 KSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDR 1201
Cdd:COG4913 383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
664-832 |
1.87e-03 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 43.46 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 664 ENSELERENRKFKKTLDSFKNLTFQLESLEKENSQL-----DEENLELRRSVESLKCASMRMAQLQLENKElESEKEQLR 738
Cdd:PTZ00419 826 NNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCyvtakDAELIELIESAENLISTLAKIGSVSVIPPI-EEEAEVPK 904
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 739 K-GLELMRASFKKTERLEVSYQgLDTENQRLQKALENSNKKIQQLESELQDLEMEnqtlQKSLEELK-ISSKRLEQLEKE 816
Cdd:PTZ00419 905 GcGFDVVDNKVIIYLNLDEFID-LKKELAKLEKKLAKLQKSLESYLKKISIPNYE----DKVPEDVRkLNDEKIDELNEE 979
|
170
....*....|....*.
gi 1720363745 817 NKSLEQETSQLEKDKK 832
Cdd:PTZ00419 980 IKQLEQAIEELKSLLK 995
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1032-1212 |
1.87e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1032 RESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL--QV 1109
Cdd:COG1579 3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYeeQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1110 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKhgtLKSAHK 1189
Cdd:COG1579 83 GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE---LEAELE 159
|
170 180 190
....*....|....*....|....*....|.
gi 1720363745 1190 NLEVEHKDLE--------DRYNQLLKQKGQL 1212
Cdd:COG1579 160 ELEAEREELAakippellALYERIRKRKNGL 190
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
839-1013 |
1.94e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 839 KRLRQQAEIkDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKT 918
Cdd:COG1579 7 RALLDLQEL-DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 919 QQMNNDLEKLTHELEKIGLNKERLlhdeqstdDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTnynQQLRHELK 998
Cdd:COG1579 85 VRNNKEYEALQKEIESLKRRISDL--------EDEILELMERIE-ELEEELAELEAELAELEAELEEKK---AELDEELA 152
|
170
....*....|....*
gi 1720363745 999 TVKKNYEALKQRQDE 1013
Cdd:COG1579 153 ELEAELEELEAEREE 167
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
453-590 |
2.07e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.84 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 453 EVNELTSSKLLKLEMENQSLTKTVE-ELRStadsaagstsKILKVEKENQRLNKKVEILENE---IIQEKQSLQNCQnls 528
Cdd:PRK12704 50 EAEAIKKEALLEAKEEIHKLRNEFEkELRE----------RRNELQKLEKRLLQKEENLDRKlelLEKREEELEKKE--- 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 529 KDLMKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQTVSSLRQRSQISAEARVKDIEKENK 590
Cdd:PRK12704 117 KELEQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEILLEKVEEEARHEAAVLIKEIEEEAK 183
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1037-1353 |
2.14e-03 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 42.36 E-value: 2.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1037 ATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqnnnLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNS 1116
Cdd:pfam15742 32 AEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQ-------AQQKLLDSTKMCSSLTAEWKHCQQKIRELELEVLKQAQ 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1117 QSTSLMNQNAQLLIQQSSLENENESIMKEREDLKS-----LYDALIKDHEKLElLHERQASEYESliskhgTLKSAHKNL 1191
Cdd:pfam15742 105 SIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHahkvcLTDTCILEKKQLE-ERIKEASENEA------KLKQQYQEE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1192 EVEHKDLEDRYNQLLKQKGQLEDLEKMIK----------TEQEKMLLESKNHEVVASEYKKLCGEndrLNYTYSQLLKET 1261
Cdd:pfam15742 178 QQKRKLLDQNVNELQQQVRSLQDKEAQLEmtnsqqqlriQQQEAQLKQLENEKRKSDEHLKSNQE---LSEKLSSLQQEK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1262 EILQMDHKNLKSVLN----NSKLEQTRLEAEFSKLKEQY----QQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQT 1333
Cdd:pfam15742 255 EALQEELQQVLKQLDvhvrKYNEKHHHHKAKLRRAKDRLvhevEQRDERIKQLENEIGILQQQSEKEKAFQKQVTAQNEI 334
|
330 340
....*....|....*....|
gi 1720363745 1334 LMLQNRTLLEQNMESKDLFH 1353
Cdd:pfam15742 335 LLLEKRKLLEQLTEQEELIK 354
|
|
| ATG14 |
pfam10186 |
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are ... |
715-851 |
2.16e-03 |
|
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are hydrophilic proteins with a predicted molecular mass of 40.5 kDa, and have a coiled-coil motif at the N terminus region. Yeast cells with mutant Atg14 are defective not only in autophagy but also in sorting of carboxypeptidase Y (CPY), a vacuolar-soluble hydrolase, to the vacuole. Subcellular fractionation indicate that Apg14p and Apg6p are peripherally associated with a membrane structure(s). Apg14p was co-immunoprecipitated with Apg6p, suggesting that they form a stable protein complex. These results imply that Apg6/Vps30p has two distinct functions: in the autophagic process and in the vacuolar protein sorting pathway. Apg14p may be a component specifically required for the function of Apg6/Vps30p through the autophagic pathway. There are 17 auto-phagosomal component proteins which are categorized into six functional units, one of which is the AS-PI3K complex (Vps30/Atg6 and Atg14). The AS-PI3K complex and the Atg2-Atg18 complex are essential for nucleation, and the specific function of the AS-PI3K apparently is to produce phosphatidylinositol 3-phosphate (PtdIns(3)P) at the pre-autophagosomal structure (PAS). The localization of this complex at the PAS is controlled by Atg14. Autophagy mediates the cellular response to nutrient deprivation, protein aggregation, and pathogen invasion in humans, and malfunction of autophagy has been implicated in multiple human diseases including cancer. This effect seems to be mediated through direct interaction of the human Atg14 with Beclin 1 in the human phosphatidylinositol 3-kinase class III complex.
Pssm-ID: 462986 [Multi-domain] Cd Length: 347 Bit Score: 42.44 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 715 CASMRMAQLQLENKELESEKEQLRKglelmrasfKKTERLEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQ 794
Cdd:pfam10186 16 CARNRLYELRVDLARLLSEKDSLKK---------KVEEALE-----GKEEGEQLEDNIGNKKLKLRLLKSEVAISNERLN 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 795 TLQKSLEELK--ISSKRlEQLEKENKSLEQETSQLEKDKKQLekENKRLRQQAEIKDTT 851
Cdd:pfam10186 82 EIKDKLDQLRreIAEKK-KKIEKLRSSLKQRRSDLESASYQL--EERRASQLAKLQNSI 137
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-854 |
2.30e-03 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 39.13 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 777 KKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENK------------SLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKvykligdvlvkqDKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90
....*....|
gi 1720363745 845 AEIKDTTLEE 854
Cdd:pfam01920 82 LEKLEKELEE 91
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
491-648 |
2.66e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 2.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 491 SKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------------SERQIKILEQ 558
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARikkyeeqlgnvrNNKEYEALQK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 559 ENEHLnqtvsslrQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELElykekgERAEELENELNHLG 638
Cdd:COG1579 97 EIESL--------KRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD------EELAELEAELEELE 162
|
170
....*....|
gi 1720363745 639 KENELLQKKI 648
Cdd:COG1579 163 AEREELAAKI 172
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
2.80e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 305 ARMYRDELDALREKAVR--VDKLESELSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRT-----SELAEAPQK--SLGHE 453
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARytpnhPDVIALRAQiaALRAQ 306
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 454 VNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILEN 512
Cdd:COG3206 307 LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
657-846 |
3.36e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 657 KLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVeslkcasmrmaqlqlenKELESEKEQ 736
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELED---ELAALEARLEAAKTELEDLEKEI-----------------KRLELEIEE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 737 LRKGLElmrasfKKTERLEvsyQGLDT-ENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKisskrlEQLEK 815
Cdd:COG1579 71 VEARIK------KYEEQLG---NVRNNkEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELE------AELAE 135
|
170 180 190
....*....|....*....|....*....|.
gi 1720363745 816 ENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG1579 136 LEAELEEKKAELDEELAELEAELEELEAERE 166
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
243-345 |
3.59e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 3.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 243 TESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARM-YRDELDALREKAVR 321
Cdd:COG4942 145 APARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEE 224
|
90 100
....*....|....*....|....*...
gi 1720363745 322 ----VDKLESELSRYKERLHDIEFYKAR 345
Cdd:COG4942 225 lealIARLEAEAAAAAERTPAAGFAALK 252
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
498-1010 |
3.72e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.12 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 498 KENQRLNKKVEILENEIIQEKQSLQ-------------NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:pfam10174 130 KELFLLRKTLEEMELRIETQKQTLGardesikkllemlQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENI 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 565 QTVSSLRQRSQISAEArvkdieKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGE-RAEELENEL--------- 634
Cdd:pfam10174 210 HLREELHRRNQLQPDP------AKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLlHTEDREEEIkqmevyksh 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 635 -----NHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLES--------LEKENSQLDE 701
Cdd:pfam10174 284 skfmkNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTevdalrlrLEEKESFLNK 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 702 ENLELRRSVESLKCASMRMAQLQ--LENKE---------LESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:pfam10174 364 KTKQLQDLTEEKSTLAGEIRDLKdmLDVKErkinvlqkkIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEE 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 771 ALENSNKKIQQL----ESELQDLEMENQTLQKSLEELK--ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKrlRQQ 844
Cdd:pfam10174 444 ALSEKERIIERLkeqrEREDRERLEELESLKKENKDLKekVSALQPELTEKESSLIDLKEHASSLASSGLKKDSK--LKS 521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 845 AEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE---NKELVKRATIDIKTLVTLREDLVSEKlktqqm 921
Cdd:pfam10174 522 LEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEvarYKEESGKAQAEVERLLGILREVENEK------ 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 922 nNDLEKLTHELEKIGLNKerllHDEQSTDDSRYKLLESKLEstlKKSLEIKEEKIAALEARLEESTNYN-QQLRHELKTV 1000
Cdd:pfam10174 596 -NDKDKKIAELESLTLRQ----MKEQNKKVANIKHGQQEMK---KKGAQLLEEARRREDNLADNSQQLQlEELMGALEKT 667
|
570
....*....|
gi 1720363745 1001 KKNYEALKQR 1010
Cdd:pfam10174 668 RQELDATKAR 677
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
240-573 |
3.98e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.25 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 240 MKRTESRQHLSVELADAkakirrlRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSArmyRDELdALREKA 319
Cdd:COG3096 274 MRHANERRELSERALEL-------RRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA---SDHL-NLVQTA 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 320 VRvdkLESELSRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG3096 343 LR---QQEKIERYQEDLEELT------ERLEEQEEVVEE----AAEQLAEAEAR---LEAAEEEVDSLKSQLADYQQALD 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 400 MDRKKIEELMEENMTLEMAQKQSMDESLHlgweLEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEEL 479
Cdd:COG3096 407 VQQTRAIQYQQAVQALEKARALCGLPDLT----PENAEDYLAAFRAKEQQATEEVLEL-EQKLSVADAARRQFEKAYELV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 480 RSTAD----SAAGSTSK-ILKVEKENQRLNKKVEILE---NEIIQEKQSLQNCQNLSKDLMK--------------EKAQ 537
Cdd:COG3096 482 CKIAGeverSQAWQTAReLLRRYRSQQALAQRLQQLRaqlAELEQRLRQQQNAERLLEEFCQrigqqldaaeeleeLLAE 561
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1720363745 538 LEKTIETL----RENSERQIKiLEQENEHLNQTVSSLRQR 573
Cdd:COG3096 562 LEAQLEELeeqaAEAVEQRSE-LRQQLEQLRARIKELAAR 600
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-935 |
4.09e-03 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 41.48 E-value: 4.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 639 KENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEEN---LELRRSVESLkc 715
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSELskaILAKSKLEKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 716 asmrMAQLQLENKELESEKEQLRKGLELMRASFK---KTERLEVSYQGLDTENQRLQKALENSN--KKIQQL--ESELQD 788
Cdd:pfam09728 76 ----CRELQKQNKKLKEESKKLAKEEEEKRKELSekfQSTLKDIQDKMEEKSEKNNKLREENEElrEKLKSLieQYELRE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 789 LEMENQTLQKSLE----ELKISSKRLEQlEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIK-------DTTLEENN 856
Cdd:pfam09728 152 LHFEKLLKTKELEvqlaEAKLQQATEEE-EKKAQEKEVAKARELKAQvQTLSETEKELREQLNLYvekfeefQDTLNKSN 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720363745 857 VKIGNLEKENKTLFKEInvykescvrlKELEKENKELVKRATIDIKTLVtlreDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:pfam09728 231 EVFTTFKKEMEKMSKKI----------KKLEKENLTWKRKWEKSNKALL----EMAEERQKLKEELEKLQKKLEKLENL 295
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
761-887 |
4.13e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 41.97 E-value: 4.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 761 LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE--- 837
Cdd:pfam05911 672 VSGSNDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkc 748
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1720363745 838 ----NKRLRQQAEIKDTTLEENNVKIGNLEKEnktLFKEINVYKESCVRLKELE 887
Cdd:pfam05911 749 maesYEDLETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQ 799
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1377 |
4.97e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.75 E-value: 4.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 682 FKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGL 761
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 762 DTENQRLQ-KALENSNKKIQQ--LESELQDLEMENQtLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQ----- 833
Cdd:pfam12128 316 AVAKDRSElEALEDQHGAFLDadIETAAADQEQLPS-WQSELENL---EERLKALTGKHQDVTAKYNRRRSKIKEqnnrd 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-NKTLFKEINVYKESCVRLKELEKENKELVKRATIdiktlvtlredlv 912
Cdd:pfam12128 392 IAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA------------- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 913 SEKLKTQQMNND--LEKLTHELEKIGLNKERLLHDEqstddsryklleskleSTLKKSLEIKEEKIAALEARLEESTNYN 990
Cdd:pfam12128 459 TPELLLQLENFDerIERAREEQEAANAEVERLQSEL----------------RQARKRRDQASEALRQASRRLEERQSAL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 991 QQLRHELKTVKKNYEALKQRQdeermvqssipVSGEDDKWGREsqeATRELLKVKDRLIEVERNNATLQAEKQALKTQLK 1070
Cdd:pfam12128 523 DELELQLFPQAGTLLHFLRKE-----------APDWEQSIGKV---ISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLK 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1071 QLETQNNNLQAQILALQRQTVSlqeqnTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLK 1150
Cdd:pfam12128 589 RIDVPEWAASEEELRERLDKAE-----EALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQ 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1151 SLYDALIK----------------DHEKLELLHERQA--SEYESLISKHGTLKSAH-KNLEVEHKDLEDRYNQLL----- 1206
Cdd:pfam12128 664 SEKDKKNKalaerkdsanerlnslEAQLKQLDKKHQAwlEEQKEQKREARTEKQAYwQVVEGALDAQLALLKAAIaarrs 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1207 KQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKL------CGENDRLNYTYSQLLKETEILQMDhkNLKSVLNNSKL 1280
Cdd:pfam12128 744 GAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLerkierIAVRRQEVLRYFDWYQETWLQRRP--RLATQLSNIER 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1281 EQTRLEAEFSKLKEqyqqlditSTKLNNQcELLSQLKGN------LEEENRHLLDQIQTLmlqNRTLLEQNMESKDLfhv 1354
Cdd:pfam12128 822 AISELQQQLARLIA--------DTKLRRA-KLEMERKASekqqvrLSENLRGLRCEMSKL---ATLKEDANSEQAQG--- 886
|
730 740
....*....|....*....|...
gi 1720363745 1355 EQRQYIDKLNELRRQKEKLEEKI 1377
Cdd:pfam12128 887 SIGERLAQLEDLKLKRDYLSESV 909
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
5.07e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.73 E-value: 5.07e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1720363745 784 SELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
505-769 |
5.49e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.45 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 505 KKVEIL-ENEIIqeKQSLQNCQNLSK---DLMKEKAQLEKtietLRENSERQIKI------LEQENEHLNQTVSSLRQRS 574
Cdd:PRK05771 7 KKVLIVtLKSYK--DEVLEALHELGVvhiEDLKEELSNER----LRKLRSLLTKLsealdkLRSYLPKLNPLREEKKKVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 575 QISAEARVKDIEKE-NKILhESIKETCGKLSKIEFEKRQMKKELelykekgERAEELENelnhLGKENELLQKKiTNLKI 653
Cdd:PRK05771 81 VKSLEELIKDVEEElEKIE-KEIKELEEEISELENEIKELEQEI-------ERLEPWGN----FDLDLSLLLGF-KYVSV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 654 TC-----EKLETLEQENSELERENRKFKKTLD--SFKNLTFQLESLEKENSQLDEENLELRRSVEslkcASMRMAQLQLE 726
Cdd:PRK05771 148 FVgtvpeDKLEELKLESDVENVEYISTDKGYVyvVVVVLKELSDEVEEELKKLGFERLELEEEGT----PSELIREIKEE 223
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1720363745 727 NKELESEKEQLRKGLElmrASFKKTERLEVSYQG-LDTENQRLQ 769
Cdd:PRK05771 224 LEEIEKERESLLEELK---ELAKKYLEELLALYEyLEIELERAE 264
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
602-910 |
5.68e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.55 E-value: 5.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 602 KLSKIEFEKRQMKKELELyKEKGERAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDS 681
Cdd:pfam05667 320 PTKVETEEELQQQREEEL-EELQEQLEDLESSIQELEKEIKKLESSIKQVE---EELEELKEQNEELEKQYKVKKKTLDL 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 682 FKNltfqleslekensqlDEENlelrrsveslkcasmrMAQLQLENKELESEKEQLRKGLELMRASfkkterlevsyqgL 761
Cdd:pfam05667 396 LPD---------------AEEN----------------IAKLQALVDASAQRLVELAGQWEKHRVP-------------L 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 762 DTENQRLQKALENSNKKIQQLESELQDLEmenQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:pfam05667 432 IEEYRALKEAKSNKEDESQRKLEEIKELR---EKIKEVAEEAKQKEELYKQLVAEYERLPKDVSRSAYTRRILEIVKNIK 508
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720363745 842 RQQAEIkdttleennVKIgnLEkENKTLFKEINVYKESCVR----LKEL-EKENK--ELVKRAtidIKTLVTLRED 910
Cdd:pfam05667 509 KQKEEI---------TKI--LS-DTKSLQKEINSLTGKLDRtftvTDELvFKDAKkdESVRKA---YKYLAALHEN 569
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1135-1357 |
5.85e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.42 E-value: 5.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1135 LENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKG---- 1210
Cdd:pfam07888 50 QEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAahea 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1211 QLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGendrlnytysqLLKETEilqMDHKNLKSVLNNSKLEQTRLEAEFS 1290
Cdd:pfam07888 130 RIRELEEDIKTLTQRVLERETELERMKERAKKAGA-----------QRKEEE---AERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720363745 1291 KLKEQYQQLDITSTKLNNQCELLSQlkgnleeenrhLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1357
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQ-----------KLTTAHRKEAENEALLEELRSLQERLNASER 251
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
239-565 |
5.91e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.86 E-value: 5.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 239 GMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDarsarmYRDELDALREK 318
Cdd:COG3096 342 ALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQ----LAD------YQQALDVQQTR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 319 AVRVDKLESELSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLegtrARSDKLHELEKENLQLKAKLHDm 394
Cdd:COG3096 412 AIQYQQAVQALEKARALCGlpdlTPENAEDYLAAFRAKEQQATEEVLELEQKL----SVADAARRQFEKAYELVCKIAG- 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 395 EMERDMDRKKIEELMEENMTLEM--AQKQSMDESLHlgwELEQISRTSELAEAPQKSLGHEVNELTSSKLLkLEMENQSL 472
Cdd:COG3096 487 EVERSQAWQTARELLRRYRSQQAlaQRLQQLRAQLA---ELEQRLRQQQNAERLLEEFCQRIGQQLDAAEE-LEELLAEL 562
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 473 TKTVEELrstADSAAGSTSKILKVEKENQRLNKKVEILEN------------EIIQEK--QSLQNCQNLSkDLMKEKAQL 538
Cdd:COG3096 563 EAQLEEL---EEQAAEAVEQRSELRQQLEQLRARIKELAArapawlaaqdalERLREQsgEALADSQEVT-AAMQQLLER 638
|
330 340
....*....|....*....|....*..
gi 1720363745 539 EKTIETLRENSERQIKILEQENEHLNQ 565
Cdd:COG3096 639 EREATVERDELAARKQALESQIERLSQ 665
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
945-1110 |
6.11e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 945 DEQSTDDSRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTN---------YNQQLRHELKTVKKNYEALKQRQDEE- 1014
Cdd:COG3206 212 EEAKLLLQQLSELESQL-AEARAELAEAEARLAALRAQLGSGPDalpellqspVIQQLRAQLAELEAELAELSARYTPNh 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1015 -RMVQSsipvsgeddkwgRESQEATRELLK--VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL---QAQILALQR 1088
Cdd:COG3206 291 pDVIAL------------RAQIAALRAQLQqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLER 358
|
170 180
....*....|....*....|..
gi 1720363745 1089 QTVSLQEQNTTLQTQNAKLQVE 1110
Cdd:COG3206 359 EVEVARELYESLLQRLEEARLA 380
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1056-1137 |
7.01e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 40.99 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1128
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 1720363745 1129 LIQQS--SLEN 1137
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
728-844 |
7.40e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.89 E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 728 KELESEKEQLRKGLELMRASFKKTERlevsyqgldtENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSleelkisS 807
Cdd:pfam13851 29 KSLKEEIAELKKKEERNEKLMSEIQQ----------ENKRLTEPLQKAQEEVEELRKQLENYEKDKQSLKNL-------K 91
|
90 100 110
....*....|....*....|....*....|....*..
gi 1720363745 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam13851 92 ARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYDK 128
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1045-1114 |
7.66e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 37.55 E-value: 7.66e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:cd22887 3 ESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
7.89e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 7.89e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1720363745 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
883-1121 |
8.20e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 40.77 E-value: 8.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 883 LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQmnndleKLTHELEKigLNKERLLHDEQSTDDSRykllesKLE 962
Cdd:PHA02562 165 LSEMDKLNKDKIRELNQQIQTL-DMKIDHIQQQIKTYN------KNIEEQRK--KNGENIARKQNKYDELV------EEA 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNyeaLKQRQDEERMVQS-------SIPVSGEDDKW----- 1030
Cdd:PHA02562 230 KTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSK---IEQFQKVIKMYEKggvcptcTQQISEGPDRItkikd 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1031 -GRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 1109
Cdd:PHA02562 307 kLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386
|
250
....*....|..
gi 1720363745 1110 ENSTLNSQSTSL 1121
Cdd:PHA02562 387 ELDKIVKTKSEL 398
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
808-1204 |
8.83e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 40.71 E-value: 8.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKtlfKEINVYKESCVRLKELE 887
Cdd:COG5185 166 GKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKA---KEIINIEEALKGFQDPE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 888 KENkELVKRATIDIKTLVTLREDLVSEKL-----KTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDSRyklleskle 962
Cdd:COG5185 243 SEL-EDLAQTSDKLEKLVEQNTDLRLEKLgenaeSSKRLNENANNLIKQFENT---KEKIAEYTKSIDIKK--------- 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 963 STLKKSLEIKE-EKIAALEARLEESTNYNQQLRHELKtvkKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATREL 1041
Cdd:COG5185 310 ATESLEEQLAAaEAEQELEESKRETETGIQNLTAEIE---QGQESLTENLEAIKEEIENIVGEVELSKSSEELDSFKDTI 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1042 LKVKDRLIEVERNNATLQAE-KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQnaklQVENSTLNSQSTS 1120
Cdd:COG5185 387 ESTKESLDEIPQNQRGYAQEiLATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISE----LNKVMREADEESQ 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 1121 LMNQNAQLLIQQSSLENENEsIMKEREDLKSLYDALIKDHEKLELLHERQaseYESLISKHGTLKSAHKNLEVEHKDLED 1200
Cdd:COG5185 463 SRLEEAYDEINRSVRSKKED-LNEELTQIESRVSTLKATLEKLRAKLERQ---LEGVRSKLDQVAESLKDFMRARGYAHI 538
|
....
gi 1720363745 1201 RYNQ 1204
Cdd:COG5185 539 LALE 542
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
596-826 |
8.91e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 8.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 596 IKETCGKLSKIEFEKRQMKKELelyKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLET-LEQENSELERENRK 674
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAEL---DALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAeIEERREELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 675 FKKTLDSFKNLTFQLESlekensqldeENL-ELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrasfKKTER 753
Cdd:COG3883 95 LYRSGGSVSYLDVLLGS----------ESFsDFLDRLSALSKIADADADLLEELKADKAELEAKKAELE------AKLAE 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720363745 754 LEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:COG3883 159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
697-868 |
1.00e-02 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 40.97 E-value: 1.00e-02
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 697 SQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQgldteNQRLQKALENSN 776
Cdd:PRK00409 509 KLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEA-----EKEAQQAIKEAK 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720363745 777 KKIQQLESELQDLEMENQTLQKSleelKISSKRLEQLEKENKSLEQETSQLEKDKKQLeKENKRLR-----QQAEI---- 847
Cdd:PRK00409 584 KEADEIIKELRQLQKGGYASVKA----HELIEARKRLNKANEKKEKKKKKQKEKQEEL-KVGDEVKylslgQKGEVlsip 658
|
170 180
....*....|....*....|....*..
gi 1720363745 848 --KDTTLEEN----NVKIGNLEKENKT 868
Cdd:PRK00409 659 ddKEAIVQAGimkmKVPLSDLEKIQKP 685
|
|
| |
