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Conserved domains on  [gi|1720422363|ref|XP_030098386|]
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ataxin-2-like protein isoform X16 [Mus musculus]

Protein Classification

SM-ATX and LsmAD domain-containing protein( domain architecture ID 13860551)

SM-ATX and LsmAD domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
1-74 2.83e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


:

Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 2.83e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363   1 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 74
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
142-204 1.34e-17

LsmAD domain; This domain is found associated with Lsm domain.


:

Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.34e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363 142 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 204
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
629-848 1.59e-10

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.06  E-value: 1.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 629 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 694
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 695 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 752
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 753 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 832
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335
                         250
                  ....*....|....*.
gi 1720422363 833 PHGFTNMAHVTQAHVQ 848
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 super family cl33720
large tegument protein UL36; Provisional
214-820 7.27e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.87  E-value: 7.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  214 GRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 293
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  294 LRGAKtlsspSNRPsgeaSVPPTSAVGRMY-----PPRSPKSAAPAPVSASCPEPPI--GSAVASSASIPVTSSVVDPGA 366
Cdd:PHA03247  2581 AVTSR-----ARRP----DAPPQSARPRAPvddrgDPRGPAPPSPLPPDTHAPDPPPpsPSPAANEPDPHPPPTVPPPER 2651
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  367 GSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleelrkfgaqfKLQPSSSPETGL-DPFP 445
Cdd:PHA03247  2652 PRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR-------------AARPTVGSLTSLaDPPP 2703
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  446 srilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeqlPAPCPSQTGSPPVGLikgdekeeG 525
Cdd:PHA03247  2704 ----------------------PPPTPEPA------------PHALVSATPLP---PGPAAARQASPALPA--------A 2738
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  526 PVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 605
Cdd:PHA03247  2739 PAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPAD 2806
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  606 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMah 685
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------PPPPSLPLGGSVAPGGDVRRRPP-- 2867
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  686 yPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATqlhghQPQPATTPtgsQPQ 763
Cdd:PHA03247  2868 -SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP-----QPQPPPPP---PPR 2938
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363  764 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 820
Cdd:PHA03247  2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
1-74 2.83e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 2.83e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363   1 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 74
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
142-204 1.34e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.34e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363 142 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 204
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
629-848 1.59e-10

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.06  E-value: 1.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 629 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 694
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 695 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 752
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 753 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 832
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335
                         250
                  ....*....|....*.
gi 1720422363 833 PHGFTNMAHVTQAHVQ 848
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 PHA03247
large tegument protein UL36; Provisional
214-820 7.27e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.87  E-value: 7.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  214 GRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 293
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  294 LRGAKtlsspSNRPsgeaSVPPTSAVGRMY-----PPRSPKSAAPAPVSASCPEPPI--GSAVASSASIPVTSSVVDPGA 366
Cdd:PHA03247  2581 AVTSR-----ARRP----DAPPQSARPRAPvddrgDPRGPAPPSPLPPDTHAPDPPPpsPSPAANEPDPHPPPTVPPPER 2651
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  367 GSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleelrkfgaqfKLQPSSSPETGL-DPFP 445
Cdd:PHA03247  2652 PRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR-------------AARPTVGSLTSLaDPPP 2703
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  446 srilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeqlPAPCPSQTGSPPVGLikgdekeeG 525
Cdd:PHA03247  2704 ----------------------PPPTPEPA------------PHALVSATPLP---PGPAAARQASPALPA--------A 2738
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  526 PVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 605
Cdd:PHA03247  2739 PAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPAD 2806
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  606 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMah 685
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------PPPPSLPLGGSVAPGGDVRRRPP-- 2867
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  686 yPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATqlhghQPQPATTPtgsQPQ 763
Cdd:PHA03247  2868 -SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP-----QPQPPPPP---PPR 2938
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363  764 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 820
Cdd:PHA03247  2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
PHA03247 PHA03247
large tegument protein UL36; Provisional
498-917 8.30e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 8.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  498 PEQLPAPCPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVlta 577
Cdd:PHA03247  2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL--- 2695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  578 gqSGLYSPQyisyipqihmgPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLV 657
Cdd:PHA03247  2696 --TSLADPP-----------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT 2762
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  658 AATPYSSYIPYNPqqfpgqPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQ 737
Cdd:PHA03247  2763 TAGPPAPAPPAAP------AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  738 SYPHHATQlhghQPQPATTPTGS---------QPQSQHAAPSPVQHQAGQAPHLGSGQPQQNlyhPGALTGTPPSLPPGP 808
Cdd:PHA03247  2837 TAPPPPPG----PPPPSLPLGGSvapggdvrrRPPSRSPAAKPAAPARPPVRRLARPAVSRS---TESFALPPDQPERPP 2909
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  809 SAQSPQSSFPQPAAVYAIHPHQQLPhgftnmahvtqahvqtgvTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSG 888
Cdd:PHA03247  2910 QPQAPPPPQPQPQPPPPPQPQPPPP------------------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGR 2971
                          410       420
                   ....*....|....*....|....*....
gi 1720422363  889 VPALSASTPSPYPYIGHPQVQSHPSQQLP 917
Cdd:PHA03247  2972 VAVPRFRVPQPAPSREAPASSTPPLTGHS 3000
 
Name Accession Description Interval E-value
SM-ATX pfam14438
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
1-74 2.83e-19

Ataxin 2 SM domain; This SM domain is found in Ataxin-2.


Pssm-ID: 464173  Cd Length: 78  Bit Score: 82.99  E-value: 2.83e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363   1 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVLLVHFR 74
Cdd:pfam14438   1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
LsmAD pfam06741
LsmAD domain; This domain is found associated with Lsm domain.
142-204 1.34e-17

LsmAD domain; This domain is found associated with Lsm domain.


Pssm-ID: 461998 [Multi-domain]  Cd Length: 65  Bit Score: 77.61  E-value: 1.34e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363 142 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 204
Cdd:pfam06741   1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
629-848 1.59e-10

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 65.06  E-value: 1.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 629 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSyiPYNPQQFPGQPAMMQPMA--------------HYPSQPVFAP 694
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRT--GYEKYKEPEPIPDLQVDAslwgvapkkaaapaPAPQPAAQPA 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 695 MLQSNPRMLTS--------------------GSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQL--HGHQPQ 752
Cdd:pfam09770 185 SLPAPSRKMMSleeveaamraqakkpaqqpaPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVT 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 753 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPqssfPQPAavyaiHPHQQL 832
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ----PAPA-----HQAHRQ 335
                         250
                  ....*....|....*.
gi 1720422363 833 PHGFTNMAHVTQAHVQ 848
Cdd:pfam09770 336 QGSFGRQAPIITHPQQ 351
PHA03247 PHA03247
large tegument protein UL36; Provisional
214-820 7.27e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.87  E-value: 7.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  214 GRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 293
Cdd:PHA03247  2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  294 LRGAKtlsspSNRPsgeaSVPPTSAVGRMY-----PPRSPKSAAPAPVSASCPEPPI--GSAVASSASIPVTSSVVDPGA 366
Cdd:PHA03247  2581 AVTSR-----ARRP----DAPPQSARPRAPvddrgDPRGPAPPSPLPPDTHAPDPPPpsPSPAANEPDPHPPPTVPPPER 2651
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  367 GSISPASPKLSLtptdvkelptkePSRnleAQELARIAGKVPGLQNEQKRfqleelrkfgaqfKLQPSSSPETGL-DPFP 445
Cdd:PHA03247  2652 PRDDPAPGRVSR------------PRR---ARRLGRAAQASSPPQRPRRR-------------AARPTVGSLTSLaDPPP 2703
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  446 srilkeeakgkekevdglltsdPMGSPVSSktesildkedkvPMAGVGGTEGPeqlPAPCPSQTGSPPVGLikgdekeeG 525
Cdd:PHA03247  2704 ----------------------PPPTPEPA------------PHALVSATPLP---PGPAAARQASPALPA--------A 2738
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  526 PVTEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 605
Cdd:PHA03247  2739 PAPPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPAD 2806
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  606 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMah 685
Cdd:PHA03247  2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-----------------PPPPSLPLGGSVAPGGDVRRRPP-- 2867
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  686 yPSQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATqlhghQPQPATTPtgsQPQ 763
Cdd:PHA03247  2868 -SRSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP-----QPQPPPPP---PPR 2938
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363  764 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 820
Cdd:PHA03247  2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
669-915 6.47e-07

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 53.50  E-value: 6.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 669 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPAAEQPTPQALYAT 734
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 735 VHQSYPHHAT------QLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 808
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI 265
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 809 SaQSPQSSFPQPAAVYA-IHPHQQLPHGFTNMAHVTQAhvqtgvtaappphpGAPHPPQVMLLHPPQGHGGPPQGAVPPS 887
Cdd:pfam09770 266 L-QRPQSPQPDPAQPSIqPQAQQFHQQPPPVPVQPTQI--------------LQNPNRLSAARVGYPQNPQPGVQPAPAH 330
                         250       260
                  ....*....|....*....|....*...
gi 1720422363 888 GVPALSASTPSPYPYIGHPQVQSHPSQQ 915
Cdd:pfam09770 331 QAHRQQGSFGRQAPIITHPQQLAQLSEE 358
PHA03247 PHA03247
large tegument protein UL36; Provisional
498-917 8.30e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 8.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  498 PEQLPAPCPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVlta 577
Cdd:PHA03247  2619 PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL--- 2695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  578 gqSGLYSPQyisyipqihmgPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLV 657
Cdd:PHA03247  2696 --TSLADPP-----------PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT 2762
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  658 AATPYSSYIPYNPqqfpgqPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQ 737
Cdd:PHA03247  2763 TAGPPAPAPPAAP------AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  738 SYPHHATQlhghQPQPATTPTGS---------QPQSQHAAPSPVQHQAGQAPHLGSGQPQQNlyhPGALTGTPPSLPPGP 808
Cdd:PHA03247  2837 TAPPPPPG----PPPPSLPLGGSvapggdvrrRPPSRSPAAKPAAPARPPVRRLARPAVSRS---TESFALPPDQPERPP 2909
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  809 SAQSPQSSFPQPAAVYAIHPHQQLPhgftnmahvtqahvqtgvTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSG 888
Cdd:PHA03247  2910 QPQAPPPPQPQPQPPPPPQPQPPPP------------------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGR 2971
                          410       420
                   ....*....|....*....|....*....
gi 1720422363  889 VPALSASTPSPYPYIGHPQVQSHPSQQLP 917
Cdd:PHA03247  2972 VAVPRFRVPQPAPSREAPASSTPPLTGHS 3000
PHA03247 PHA03247
large tegument protein UL36; Provisional
276-822 1.63e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  276 ARGINGGPSRMSPKAQRPLRGAKTLSSPSNR--PSGEASVPPTSAVGRMYPPRSPKSAAPAPvsASCPEPPIGSAVASS- 352
Cdd:PHA03247  2456 ARTILGAPFSLSLLLGELFPGAPVYRRPAEArfPFAAGAAPDPGGGGPPDPDAPPAPSRLAP--AILPDEPVGEPVHPRm 2533
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  353 -ASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPS-RNLEAQELARiaGKVPGLQNEQKRFQLEELRKFGAQFK 430
Cdd:PHA03247  2534 lTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPApRPSEPAVTSR--ARRPDAPPQSARPRAPVDDRGDPRGP 2611
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  431 LQPSSSPETGLDPFPsrilkeeakgkekevdglltsdPMGSPVSSKTESILDKEDKVPmagvggtEGPEQLPAPCPSQTG 510
Cdd:PHA03247  2612 APPSPLPPDTHAPDP----------------------PPPSPSPAANEPDPHPPPTVP-------PPERPRDDPAPGRVS 2662
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  511 SPPVGLIKGDEKEEGPVTEQVKKSTLNPnakefnPTKPLLSVNKSTSTPTSPGPRTHS-TPSIPVLTAGQSGLYSPqyis 589
Cdd:PHA03247  2663 RPRRARRLGRAAQASSPPQRPRRRAARP------TVGSLTSLADPPPPPPTPEPAPHAlVSATPLPPGPAAARQAS---- 2732
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  590 yiPQIHMGPAVQAPQMYP-YPVSNSVPGQQGKYRGAKGSLPPQrsdqhQPASAPPMMQAAAAAAGPPLVAATPYSSYIPY 668
Cdd:PHA03247  2733 --PALPAAPAPPAVPAGPaTPGGPARPARPPTTAGPPAPAPPA-----APAAGPPRRLTRPAVASLSESRESLPSPWDPA 2805
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  669 NPQQFPGQPAMMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQ--AIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQ 745
Cdd:PHA03247  2806 DPPAAVLAPAAALPPAASPAGPLPPPTsAQPTAPPPPPGPPPPslPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRR 2885
                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720422363  746 LHGHQPQPattPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 822
Cdd:PHA03247  2886 LARPAVSR---STESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
748-823 1.39e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 45.54  E-value: 1.39e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720422363 748 GHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAphlgSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 823
Cdd:PRK14971  389 APQPSAAAAASPSPSQSSAAAQPSAPQSATQP----AGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPV 460
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
719-921 1.64e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.41  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 719 QYPAAEQPTPQALYATVHQSYPHHATQLHGHQPQPATT---------------------PTGSQPQSQHAAPSPVQHQAG 777
Cdd:pfam09770 105 QQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTgyekykepepipdlqvdaslwGVAPKKAAAPAPAPQPAAQPA 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 778 QAPHLG-------------SGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQ 844
Cdd:pfam09770 185 SLPAPSrkmmsleeveaamRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVT 264
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422363 845 AHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQV--QSHPSQQLPFHPP 921
Cdd:pfam09770 265 ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPahQAHRQQGSFGRQA 343
PRK10927 PRK10927
cell division protein FtsN;
719-822 3.95e-04

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 43.52  E-value: 3.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 719 QYPAAEQPTPQalyatvHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALT 798
Cdd:PRK10927  144 QTPEQRQQTLQ------RQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHT 217
                          90       100
                  ....*....|....*....|....*
gi 1720422363 799 GTPPSLP-PGPSAQSPQSsfPQPAA 822
Cdd:PRK10927  218 TAQSKPQqAAPVTRAADA--PKPTA 240
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
252-573 5.00e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 5.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 252 PGLSSLPPRGPHHLDNSS----PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP--SGEASVPPTSAVGRmyPP 325
Cdd:PTZ00449  514 PEASGLPPKAPGDKEGEEgeheDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPtlSKKPEFPKDPKHPK--DP 591
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 326 RSPKSAApAPVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLT---PTDVKELPTKEPSRnleaqelar 402
Cdd:PTZ00449  592 EEPKKPK-RPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSperPEGPKIIKSPKPPK--------- 661
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 403 iAGKVPglqneqkrFQLEELRKFGAQFKLQPSSSPETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMG-SPVSSKTESIL 481
Cdd:PTZ00449  662 -SPKPP--------FDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPlPPKLPRDEEFP 732
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 482 DKEDKVPMAgvggtegpeqlPAPCPSQTGSPPVGL------IKGDEKEEGPVTEQVKKSTLNPNAKEfnPTKPLLSVNKS 555
Cdd:PTZ00449  733 FEPIGDPDA-----------EQPDDIEFFTPPEEErtffheTPADTPLPDILAEEFKEEDIHAETGE--PDEAMKRPDSP 799
                         330
                  ....*....|....*....
gi 1720422363 556 TS-TPTSPGprTHstPSIP 573
Cdd:PTZ00449  800 SEhEDKPPG--DH--PSLP 814
Herpes_TAF50 pfam03326
Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 ...
498-794 5.44e-04

Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 and similar ORF 50 proteins from other herpesviruses.


Pssm-ID: 308764 [Multi-domain]  Cd Length: 568  Bit Score: 43.53  E-value: 5.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 498 PEQLPAPCPSQTGSPP----VGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 573
Cdd:pfam03326 269 PQRLQAPGFSRSTSRPargqTAQYFLAAQQHGVVSLFPSTATLVPIAGSTGVTEVVSYGHNSTSPSSTPCPSTAVTEADH 348
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 574 VLTAGQSGLYSPQYISYipQIHMGPAVQAPQMYPYPvsnsvpgqqGKYRGAKGsLPPQRSDQHQPAsappmmqAAAAAAG 653
Cdd:pfam03326 349 QTEPEVPWIATAHQESD--QRPIGPGPEKPTFLPPV---------GGKQFFQG-LRDSRSTSFLTA-------PEATSAI 409
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 654 PPLVAATPYSSYIPYNPQQFPGQPammqpmahypsqpvfapmlqSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYA 733
Cdd:pfam03326 410 SDVFQGTEVCQPKRIRALHPPGSP--------------------SANRPLPSSLAPTPTGPVHEPGSSLTPATVPQPLDA 469
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720422363 734 T--VHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 794
Cdd:pfam03326 470 ApvATPEASHELQPPDEETPQPLDEDQALCGQQDASHPPPRGQLDELTTTLESMTEDLNLDSP 532
PRK10263 PRK10263
DNA translocase FtsK; Provisional
671-828 5.61e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 43.92  E-value: 5.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  671 QQFPG-QPAMMQPMAHypSQPVFAPMlqsnPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHATQLHGH 749
Cdd:PRK10263   709 QRYSGeQPAGANPFSL--DDFEFSPM----KALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQ 782
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720422363  750 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQnlyhpgaltgtpPSLPPGPSAQSPQSSFPQPAAVYaIHP 828
Cdd:PRK10263   783 QPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQ------------PVAPQPQYQQPQQPVAPQPQDTL-LHP 848
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
293-429 9.44e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.84  E-value: 9.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 293 PLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRS---PKSAAPAPVSASCPEPPIGSaVASSASIPVTSSVVDPGAGSI 369
Cdd:PRK14971  371 GGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSsaaAQPSAPQSATQPAGTPPTVS-VDPPAAVPVNPPSTAPQAVRP 449
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720422363 370 SPASPKLSLTPTDV--KELPTKEPSRNLEAQELARIAGKVPGLQNEQkrFQLEELRKFGAQF 429
Cdd:PRK14971  450 AQFKEEKKIPVSKVssLGPSTLRPIQEKAEQATGNIKEAPTGTQKEI--FTEEDLQYYWQEF 509
PHA03247 PHA03247
large tegument protein UL36; Provisional
427-920 2.38e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  427 AQFKLQPSSSPETGLDPFPSrilKEEAKGKEKEVDGLLTSDPMGSPVSSKTESILDKEDKVPMAGVGGTEG--PEQLPAP 504
Cdd:PHA03247  2486 ARFPFAAGAAPDPGGGGPPD---PDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPplPPAAPPA 2562
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  505 CPSQTGSPPvglikgdEKEEGPVTEQVKKSTLNPNAKEfNPTKPLLSVNKSTSTPTSPGPrTHSTPSIPVLTAGQSGLYS 584
Cdd:PHA03247  2563 APDRSVPPP-------RPAPRPSEPAVTSRARRPDAPP-QSARPRAPVDDRGDPRGPAPP-SPLPPDTHAPDPPPPSPSP 2633
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  585 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAAGPPLVAAT 660
Cdd:PHA03247  2634 AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRaRRLGRAAQASSPPQRPRRRAarpTVGSLTSLADPPPPPPTPEPAPH 2713
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  661 PYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAeQPTPQALYATVhqsy 739
Cdd:PHA03247  2714 ALVSATPLPPgPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA-GPPRRLTRPAV---- 2788
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  740 phhatqlhghqpQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPsaqsPQSSFPQ 819
Cdd:PHA03247  2789 ------------ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP----PPPSLPL 2852
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  820 PAAVYAIHP-HQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQvmllhPPQGHGGPPQGAVPPSGVPalsaSTPS 898
Cdd:PHA03247  2853 GGSVAPGGDvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-----PPDQPERPPQPQAPPPPQP----QPQP 2923
                          490       500
                   ....*....|....*....|..
gi 1720422363  899 PYPYIGHPQVQSHPSQQLPFHP 920
Cdd:PHA03247  2924 PPPPQPQPPPPPPPRPQPPLAP 2945
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
267-401 4.02e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 4.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 267 NSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRSPKSAA-------------P 333
Cdd:PRK12323  371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAArqasargpggapaP 450
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720422363 334 APVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTdVKELPTKEPSRNLEAQELA 401
Cdd:PRK12323  451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP-WEELPPEFASPAPAQPDAA 517
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
205-393 4.68e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 4.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  205 HSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR------GPHHLDNSSPGPGSEARG 278
Cdd:PHA03307   171 QAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRsaaddaGASSSDSSSSESSGCGWG 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  279 INGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRSPKSA-------APAPVSASCPEPPIGSAVAS 351
Cdd:PHA03307   251 PENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPgsgpapsSPRASSSSSSSRESSSSSTS 330
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1720422363  352 SASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPSR 393
Cdd:PHA03307   331 SSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPS 372
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
629-822 4.80e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.63  E-value: 4.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 629 PPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 708
Cdd:PRK12323  365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 709 PQAIVSSSTP-------QYPAAEQPTPQALYATVHQSYPHHATQlhgHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 781
Cdd:PRK12323  445 GGAPAPAPAPaaapaaaARPAAAGPRPVAAAAAAAPARAAPAAA---PAPADDDPPPWEELPPEFASPAPAQPDAAPAGW 521
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1720422363 782 LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 822
Cdd:PRK12323  522 VAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVA 562
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
272-408 5.63e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 40.46  E-value: 5.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 272 PGSEARGINGGPSRMSPKAQRPLRGAKTlSSPSNRPSGEASVPPTSAVGRMYPPRSPKSAAPA--------PVSASCPEP 343
Cdd:PRK08691  364 ASCDANAVIENTELQSPSAQTAEKETAA-KKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVsnqenndvPPWEDAPDE 442
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720422363 344 ---PIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEPSR---NLEAQELARIAGKVP 408
Cdd:PRK08691  443 aqtAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEVPSENPIQatpNDEAVETETFAHEAP 513
PHA03247 PHA03247
large tegument protein UL36; Provisional
506-922 5.72e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 5.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  506 PSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSV----NKSTSTPTSPGPRTHSTPSIPVLTAGQSg 581
Cdd:PHA03247  2489 PFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRMLTwirgLEELASDDAGDPPPPLPPAAPPAAPDRS- 2567
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  582 LYSPQYISYIPqihmGPAVQA----PQMYPYPVSNSVPGQ-QGKYRG--AKGSLPPQRSDQHQPASAPPMMQAAAAAAGP 654
Cdd:PHA03247  2568 VPPPRPAPRPS----EPAVTSrarrPDAPPQSARPRAPVDdRGDPRGpaPPSPLPPDTHAPDPPPPSPSPAANEPDPHPP 2643
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  655 PLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPvfapmlqsnPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYAT 734
Cdd:PHA03247  2644 PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP---------PQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHA 2714
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  735 VHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNlyHPGALTGTPP---SLPPGPSAQ 811
Cdd:PHA03247  2715 LVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPA--PPAAPAAGPPrrlTRPAVASLS 2792
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363  812 SPQSSFPQPAAVyAIHPHQQLPHGFTNMAHVTQAHVQTGVTAAPPPHPGAPHPPQVMLLhpPQGHGGPPQGAV---PPSG 888
Cdd:PHA03247  2793 ESRESLPSPWDP-ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL--PLGGSVAPGGDVrrrPPSR 2869
                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1720422363  889 VPALSASTPS--PYPYIGHPQVqSHPSQQLPFHPPG 922
Cdd:PHA03247  2870 SPAAKPAAPArpPVRRLARPAV-SRSTESFALPPDQ 2904
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
611-922 6.72e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.52  E-value: 6.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 611 SNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQ 689
Cdd:pfam03154 145 SPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPqGSPATSQPPNQTQST 224
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 690 PVFAPMLQSNPRMltsgsHPQAIVSSSTPQYPAAEQPTPQALYATVHQSYPHHatqlhghqpqpatTPTGSQPQSQHAAP 769
Cdd:pfam03154 225 AAPHTLIQQTPTL-----HPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLH-------------GQMPPMPHSLQTGP 286
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720422363 770 SPVQHQAGQAPHLGSGQPQQNLYHPGaltgtPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQ-LPHgftnmAHVTQAHVQ 848
Cdd:pfam03154 287 SHMQHPVPPQPFPLTPQSSQSQVPPG-----PSPAAPGQSQQRIHTPPSQSQLQSQQPPREQpLPP-----APLSMPHIK 356
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720422363 849 TGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSAST---PSPYPYIGHPQVQSHPSQQLPFHPPG 922
Cdd:pfam03154 357 PPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLSThhpPSAHPPPLQLMPQSQQLPPPPAQPPV 433
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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