|
Name |
Accession |
Description |
Interval |
E-value |
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
954-1221 |
9.41e-46 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 174.58 E-value: 9.41e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 954 SIDFYQVCFVYPQLHHNIKNGSLmltlydftaKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmn 1033
Cdd:COG1132 339 EIEFENVSFSYPGDRPVLKDISL---------TIPPGETVALVGPSGSGKSTLVNLLLRFYDP----------------- 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 ceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMV 1113
Cdd:COG1132 393 ------------------------TSGRILIDGVDIRDLTLESLRRQIGVVPQDTFLF-SGTIRENIRYGRPDAT-DEEV 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 ITSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFM 1189
Cdd:COG1132 447 EEAAKAAQAHEFIEALPDGYDTVVGergvNLSGGQRQRIAIARALLKDPP---ILILDEATSALDTETEALIQEALERLM 523
|
250 260 270
....*....|....*....|....*....|..
gi 1624762192 1190 RARggsTAIIISHRPSALRLAGRVVLLgDGGR 1221
Cdd:COG1132 524 KGR---TTIVIAHRLSTIRNADRILVL-DDGR 551
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
951-1231 |
5.73e-45 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 174.64 E-value: 5.73e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 951 LSKSIDFYQVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmi 1030
Cdd:COG2274 470 LKGDIELENVSFRYPGDSPPV--------LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEP-------------- 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1031 wmnceelinifrycylelslplpnkeDSANIiRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvR 1110
Cdd:COG2274 528 --------------------------TSGRI-LIDGIDLRQIDPASLRRQIGVVLQDVFLF-SGTIRENITLGDPDAT-D 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1111 EMVITSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALA 1186
Cdd:COG2274 579 EEIIEAARLAGLHDFIEALPMGYDTVVGeggsNLSGGQRQRLAIARALLRN---PRILILDEATSALDAETEAIILENLR 655
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1624762192 1187 EFmraRGGSTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:COG2274 656 RL---LKGRTVIIIAHRLSTIRLADRIIVL-DKGRIVEDGTHEEL 696
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
955-1220 |
7.28e-43 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 156.55 E-value: 7.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIkngslmlTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03249 1 IEFKNVSFRYPSRPDVP-------ILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDP------------------ 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASVrEMVI 1114
Cdd:cd03249 56 -----------------------TSGEILLDGVDIRDLNLRWLRSQIGLVSQEPVLF-DGTIAENIRYGKPDATD-EEVE 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMR 1190
Cdd:cd03249 111 EAAKKANIHDFIMSLPDGYDTLVGergsQLSGGQKQRIAIARALLRNPK---ILLLDEATSALDAESEKLVQEALDRAMK 187
|
250 260 270
....*....|....*....|....*....|
gi 1624762192 1191 ARggsTAIIISHRPSALRLAGRVVLLGDGG 1220
Cdd:cd03249 188 GR---TTIVIAHRLSTIRNADLIAVLQNGQ 214
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
955-1220 |
1.02e-42 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 155.85 E-value: 1.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03251 1 VEFKNVTFRYPGDGPPV--------LRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDV------------------ 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMVI 1114
Cdd:cd03251 55 -----------------------DSGRILIDGHDVRDYTLASLRRQIGLVSQDVFLF-NDTVAENIAYGRPGAT-REEVE 109
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEFMR 1190
Cdd:cd03251 110 EAARAANAHEFIMELPEGYDTVIGergvKLSGGQRQRIAIARALL---KDPPILILDEATSALDTESERLVQAALERLMK 186
|
250 260 270
....*....|....*....|....*....|
gi 1624762192 1191 ARggsTAIIISHRPSALRLAGRVVLLGDGG 1220
Cdd:cd03251 187 NR---TTFVIAHRLSTIENADRIVVLEDGK 213
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
954-1219 |
4.27e-42 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 163.39 E-value: 4.27e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 954 SIDFYQVCFVYPQLHHnikngslmlTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmn 1033
Cdd:COG4988 336 SIELEDVSFSYPGGRP---------ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPP----------------- 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 ceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMV 1113
Cdd:COG4988 390 ------------------------YSGSILINGVDLSDLDPASWRRQIAWVPQNPYLF-AGTIRENLRLGRPDAS-DEEL 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 ITSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFM 1189
Cdd:COG4988 444 EAALEAAGLDEFVAALPDGLDTPLGeggrGLSGGQAQRLALARALLRDAP---LLLLDEPTAHLDAETEAEILQALRRLA 520
|
250 260 270
....*....|....*....|....*....|
gi 1624762192 1190 RARggsTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:COG4988 521 KGR---TVILITHRLALLAQADRILVLDDG 547
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
955-1219 |
1.11e-40 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 147.91 E-value: 1.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03228 1 IEFKNVSFSYPGRPKPV--------LKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDP------------------ 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkeDSANIiRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENIsffadnasvremvi 1114
Cdd:cd03228 55 ----------------------TSGEI-LIDGVDLRDLDLESLRKNIAYVPQDPFLF-SGTIRENI-------------- 96
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 tsarvcrcesfiknhplsydapvgrLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRargG 1194
Cdd:cd03228 97 -------------------------LSGGQRQRIAIARALLRDPP---ILILDEATSALDPETEALILEALRALAK---G 145
|
250 260
....*....|....*....|....*
gi 1624762192 1195 STAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:cd03228 146 KTVIVIAHRLSTIRDADRIIVLDDG 170
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
954-1219 |
2.12e-40 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 158.39 E-value: 2.12e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 954 SIDFYQVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmn 1033
Cdd:COG4987 333 SLELEDVSFRYPGAGRPV--------LDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDP----------------- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 ceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASVREMV 1113
Cdd:COG4987 388 ------------------------QSGSITLGGVDLRDLDEDDLRRRIAVVPQRPHLF-DTTLRENLRLARPDATDEELW 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 ITSARVcRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEgcvEEALAEFM 1189
Cdd:COG4987 443 AALERV-GLGDWLAALPDGLDTWLGeggrRLSGGERRRLALARALLRDAP---ILLLDEPTEGLDAATE---QALLADLL 515
|
250 260 270
....*....|....*....|....*....|
gi 1624762192 1190 RARGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:COG4987 516 EALAGRTVLLITHRLAGLERMDRILVLEDG 545
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
955-1231 |
3.96e-39 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 145.45 E-value: 3.96e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIKNgslmltlYDFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03254 3 IEFENVNFSYDEKKPVLKD-------INFSIK--PGETVAIVGPTGAGKTTLINLLMRFYDP------------------ 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkeDSANIIrLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMVI 1114
Cdd:cd03254 56 ----------------------QKGQIL-IDGIDIRDISRKSLRSMIGVVLQDTFLF-SGTIMENIRLGRPNAT-DEEVI 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEFMR 1190
Cdd:cd03254 111 EAAKEAGAHDFIMKLPNGYDTVLGenggNLSQGERQLLAIARAML---RDPKILILDEATSNIDTETEKLIQEALEKLMK 187
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1624762192 1191 ARggsTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:cd03254 188 GR---TSIIIAHRLSTIKNADKILVL-DDGKIIEEGTHDEL 224
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
954-1221 |
2.87e-38 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 142.73 E-value: 2.87e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 954 SIDFYQVCFVYP-QLHHNIKNGSLmltlydftaKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwm 1032
Cdd:cd03245 2 RIEFRNVSFSYPnQEIPALDNVSL---------TIRAGEKVAIIGRVGSGKSTLLKLLAGLYKP---------------- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1033 nceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREM 1112
Cdd:cd03245 57 -------------------------TSGSVLLDGTDIRQLDPADLRRNIGYVPQDVTLF-YGTLRDNITLGAPLAD-DER 109
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1113 VITSARVCRCESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEF 1188
Cdd:cd03245 110 ILRAAELAGVTDFVNKHPNGLDLQIGErgrgLSGGQRQAVALARALLNDPP---ILLLDEPTSAMDMNSEERLKERLRQL 186
|
250 260 270
....*....|....*....|....*....|...
gi 1624762192 1189 mraRGGSTAIIISHRPSALRLAGRVVLLgDGGR 1221
Cdd:cd03245 187 ---LGDKTLIIITHRPSLLDLVDRIIVM-DSGR 215
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
952-1216 |
1.69e-35 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 142.81 E-value: 1.69e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 952 SKSIDFYQVCFVYPqlhhnikNGSLMLTLYDFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPVRtikidenfnnmiw 1031
Cdd:TIGR02857 319 ASSLEFSGVSVAYP-------GRRPALRPVSFT--VPPGERVALVGPSGAGKSTLLNLLLGFVDPTE------------- 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1032 mnceelinifrycylelslplpnkedsaNIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASvRE 1111
Cdd:TIGR02857 377 ----------------------------GSIAVNGVPLADADADSWRDQIAWVPQHPFLFAG-TIAENIRLARPDAS-DA 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1112 MVITSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEGCVEEALAE 1187
Cdd:TIGR02857 427 EIREALERAGLDEFVAALPQGLDTPIGeggaGLSGGQAQRLALARAFLR---DAPLLLLDEPTAHLDAETEAEVLEALRA 503
|
250 260
....*....|....*....|....*....
gi 1624762192 1188 FMRARggsTAIIISHRPSALRLAGRVVLL 1216
Cdd:TIGR02857 504 LAQGR---TVLLVTHRLALAALADRIVVL 529
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
955-1219 |
2.94e-35 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 134.67 E-value: 2.94e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIKNGSlmltlydFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03253 1 IEFENVTFAYDPGRPVLKDVS-------FTIP--AGKKVAIVGPSGSGKSTILRLLFRFYDV------------------ 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNpCVFENMTFFENISFFADNASvREMVI 1114
Cdd:cd03253 54 -----------------------SSGSILIDGQDIREVTLDSLRRAIGVVPQD-TVLFNDTIGYNIRYGRPDAT-DEEVI 108
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALaefMR 1190
Cdd:cd03253 109 EAAKAAQIHDKIMRFPDGYDTIVGerglKLSGGEKQRVAIARAILKN---PPILLLDEATSALDTHTEREIQAAL---RD 182
|
250 260
....*....|....*....|....*....
gi 1624762192 1191 ARGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:cd03253 183 VSKGRTTIVIAHRLSTIVNADKIIVLKDG 211
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
959-1227 |
2.39e-29 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 124.86 E-value: 2.39e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 959 QVCFVYPqlhhniknGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceeli 1038
Cdd:COG4618 335 NLTVVPP--------GSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPP---------------------- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1039 nifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADnASvREMVITSAR 1118
Cdd:COG4618 385 -------------------TAGSVRLDGADLSQWDREELGRHIGYLPQDVELFDG-TIAENIARFGD-AD-PEKVVAAAK 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1119 VCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDghSEGcvEEALAEF---MRA 1191
Cdd:COG4618 443 LAGVHEMILRLPDGYDTRIGeggaRLSGGQRQRIGLARALYGDPR---LVVLDEPNSNLD--DEG--EAALAAAiraLKA 515
|
250 260 270
....*....|....*....|....*....|....*.
gi 1624762192 1192 RGGsTAIIISHRPSALRLAGRVVLLGDGGRSMYeGP 1227
Cdd:COG4618 516 RGA-TVVVITHRPSLLAAVDKLLVLRDGRVQAF-GP 549
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
941-1219 |
9.43e-29 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 123.15 E-value: 9.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 941 DIGRIIGgfslskSIDFYQVCFVYPQLHHNIKNGSlmltlydFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPvrti 1020
Cdd:PRK13657 327 DLGRVKG------AVEFDDVSFSYDNSRQGVEDVS-------FEAK--PGQTVAIVGPTGAGKSTLINLLQRVFDP---- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1021 kidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENI 1100
Cdd:PRK13657 388 -------------------------------------QSGRILIDGTDIRTVTRASLRRNIAVVFQDAGLF-NRSIEDNI 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1101 SFFADNASVREMVITSARVCRCEsFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGH 1176
Cdd:PRK13657 430 RVGRPDATDEEMRAAAERAQAHD-FIERKPDGYDTVVGergrQLSGGERQRLAIARALLKD---PPILILDEATSALDVE 505
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1624762192 1177 SEGCVEEALAEFMRARggsTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK13657 506 TEAKVKAALDELMKGR---TTFIIAHRLSTVRNADRILVFDNG 545
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
980-1226 |
5.39e-28 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 113.74 E-value: 5.39e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSA 1059
Cdd:cd03252 18 LDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVP----------------------------------------ENG 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIrLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFfADNASVREMVITSARVCRCESFIKNHPLSYDAPVGR 1139
Cdd:cd03252 58 RVL-VDGHDLALADPAWLRRQVGVVLQENVLF-NRSIRDNIAL-ADPGMSMERVIEAAKLAGAHDFISELPEGYDTIVGE 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 ----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARggsTAIIISHRPSALRLAGRVVL 1215
Cdd:cd03252 135 qgagLSGGQRQRIAIARALIHN---PRILIFDEATSALDYESEHAIMRNMHDICAGR---TVIIIAHRLSTVKNADRIIV 208
|
250
....*....|.
gi 1624762192 1216 LgDGGRSMYEG 1226
Cdd:cd03252 209 M-EKGRIVEQG 218
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
980-1219 |
6.02e-28 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 112.60 E-value: 6.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:COG4619 16 LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPP-----------------------------------------TS 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTTFLRKAFGILEQNPCVF-----ENMTF-FENISFFADNASVREMVitsARVCRCESFIknhplsy 1133
Cdd:COG4619 55 GEIYLDGKPLSAMPPPEWRRQVAYVPQEPALWggtvrDNLPFpFQLRERKFDRERALELL---ERLGLPPDIL------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmRARGGSTAIIISHRPS-ALRLAGR 1212
Cdd:COG4619 125 DKPVERLSGGERQRLALIRALLLQPD---VLLLDEPTSALDPENTRRVEELLREY-LAEEGRAVLWVSHDPEqIERVADR 200
|
....*..
gi 1624762192 1213 VVLLGDG 1219
Cdd:COG4619 201 VLTLEAG 207
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
955-1221 |
8.70e-28 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 112.95 E-value: 8.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPqlhhnikNGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03248 12 VKFQNVTFAYP-------TRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQP------------------ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASVrEMVI 1114
Cdd:cd03248 67 -----------------------QGGQVLLDGKPISQYEHKYLHSKVSLVGQEPVLFAR-SLQDNIAYGLQSCSF-ECVK 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMR 1190
Cdd:cd03248 122 EAAQKAHAHSFISELASGYDTEVGekgsQLSGGQKQRVAIARALIRN---PQVLILDEATSALDAESEQQVQQALYDWPE 198
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1191 ARggsTAIIISHRPSALRLAGRVVLLgDGGR 1221
Cdd:cd03248 199 RR---TVLVIAHRLSTVERADQILVL-DGGR 225
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
982-1222 |
1.21e-27 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 122.06 E-value: 1.21e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYD-------PVRTIKIDENFNNMIWMNCEE----LINIFRYCYLELSl 1050
Cdd:PTZ00265 1186 DLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDlkndhhiVFKNEHTNDMTNEQDYQGDEEqnvgMKNVNEFSLTKEG- 1264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1051 plPNKEDSANI-----IRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMVITSARVCRCESF 1125
Cdd:PTZ00265 1265 --GSGEDSTVFknsgkILLDGVDICDYNLKDLRNLFSIVSQEPMLF-NMSIYENIKFGKEDAT-REDVKRACKFAAIDEF 1340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1126 IKNHPLSYDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIIS 1201
Cdd:PTZ00265 1341 IESLPNKYDTNVGpygkSLSGGQKQRIAIARALLRE---PKILLLDEATSSLDSNSEKLIEKTIVD-IKDKADKTIITIA 1416
|
250 260
....*....|....*....|.
gi 1624762192 1202 HRPSALRLAGRVVLLGDGGRS 1222
Cdd:PTZ00265 1417 HRIASIKRSDKIVVFNNPDRT 1437
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
982-1219 |
2.86e-27 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 118.77 E-value: 2.86e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:COG5265 378 SFEVP--AGKTVAIVGPSGAGKSTLARLLFRFYDV-----------------------------------------TSGR 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMVITSARVCRCESFIKNHPLSYDAPVG--- 1138
Cdd:COG5265 415 ILIDGQDIRDVTQASLRAAIGIVPQDTVLF-NDTIAYNIAYGRPDAS-EEEVEAAARAAQIHDFIESLPDGYDTRVGerg 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 -RLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARggsTAIIISHRPSALRLAGRVVLLG 1217
Cdd:COG5265 493 lKLSGGEKQRVAIARTLL---KNPPILIFDEATSALDSRTERAIQAALREVARGR---TTLVIAHRLSTIVDADEILVLE 566
|
..
gi 1624762192 1218 DG 1219
Cdd:COG5265 567 AG 568
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
982-1218 |
4.62e-27 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 109.88 E-value: 4.62e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTakFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceelinifrycyLELSLPlpnkedSANI 1061
Cdd:COG4133 22 SFT--LAAGEALALTGPNGSGKTTLLRIL-----------------------------------AGLLPP------SAGE 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTFlRKAFGILEQNPCVFENMTFFENISFFAD--NASVREMVITSA-RVCRCESFIknhplsyDAPVG 1138
Cdd:COG4133 59 VLWNGEPIRDAREDY-RRRLAYLGHADGLKPELTVRENLRFWAAlyGLRADREAIDEAlEAVGLAGLA-------DLPVR 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmRARGGsTAIIISHRPSALRLAgRVVLLGD 1218
Cdd:COG4133 131 QLSAGQKRRVALARLLLSPAP---LWLLDEPFTALDAAGVALLAELIAAH-LARGG-AVLLTTHQPLELAAA-RVLDLGD 204
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
959-1219 |
6.07e-27 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 108.46 E-value: 6.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 959 QVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceeli 1038
Cdd:cd03246 5 NVSFRYPGAEPPV--------LRNVSFSIEPGESLAIIGPSGSGKSTLARLI---------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1039 nifrycyLELSLPlpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENIsffadnasvremvitsar 1118
Cdd:cd03246 49 -------LGLLRP------TSGRVRLDGADISQWDPNELGDHVGYLPQDDELFSG-SIAENI------------------ 96
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1119 vcrcesfiknhplsydapvgrLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARGgSTAI 1198
Cdd:cd03246 97 ---------------------LSGGQRQRLGLARALYGNPR---ILVLDEPNSHLDVEGERALNQAIAA-LKAAG-ATRI 150
|
250 260
....*....|....*....|.
gi 1624762192 1199 IISHRPSALRLAGRVVLLGDG 1219
Cdd:cd03246 151 VIAHRPETLASADRILVLEDG 171
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
980-1231 |
4.96e-26 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 107.65 E-value: 4.96e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVRTIKIDENfnnmIWMnceelinifrycylelslplpnkeDSA 1059
Cdd:cd03260 16 LKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPDEGE----VLL------------------------DGK 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIAcfsttfLRKAFGILEQNPCVFeNMTFFENISF------FADNASVREMVITSAR-------VCRcesfi 1126
Cdd:cd03260 68 DIYDLDVDVLE------LRRRVGMVFQKPNPF-PGSIYDNVAYglrlhgIKLKEELDERVEEALRkaalwdeVKD----- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1127 KNHPLSydapvgrLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARggsTAIIISHRPS- 1205
Cdd:cd03260 136 RLHALG-------LSGGQQQRLCLARALA---NEPEVLLLDEPTSALDPISTAKIEELIAELKKEY---TIVIVTHNMQq 202
|
250 260
....*....|....*....|....*.
gi 1624762192 1206 ALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:cd03260 203 AARVADRTAFL-LNGRLVEFGPTEQI 227
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
955-1219 |
5.59e-26 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 115.20 E-value: 5.59e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPqlhhnikNGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:TIGR00958 479 IEFQDVSFSYP-------NRPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQP------------------ 533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASvREMVI 1114
Cdd:TIGR00958 534 -----------------------TGGQVLLDGVPLVQYDHHYLHRQVALVGQEPVLF-SGSVRENIAYGLTDTP-DEEIM 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEAlaefmR 1190
Cdd:TIGR00958 589 AAAKAANAHDFIMEFPNGYDTEVGekgsQLSGGQKQRIAIARALVRKPR---VLILDEATSALDAECEQLLQES-----R 660
|
250 260
....*....|....*....|....*....
gi 1624762192 1191 ARGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:TIGR00958 661 SRASRTVLLIAHRLSTVERADQILVLKKG 689
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
980-1219 |
3.56e-25 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 104.91 E-value: 3.56e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:cd03259 16 LDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERP-----------------------------------------DS 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACfsTTFLRKAFGILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPlsyd 1134
Cdd:cd03259 55 GEILIDGRDVTG--VPPERRNIGMVFQDYALFPHLTVAENIAFglklrGVPKAEIRARVRELLELVGLEGLLNRYP---- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 apvGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDghsegcveEALAEFMR-------ARGGSTAIIISHRPS-A 1206
Cdd:cd03259 129 ---HELSGGQQQRVALARALAR---EPSLLLLDEPLSALD--------AKLREELReelkelqRELGITTIYVTHDQEeA 194
|
250
....*....|...
gi 1624762192 1207 LRLAGRVVLLGDG 1219
Cdd:cd03259 195 LALADRIAVMNEG 207
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
955-1219 |
4.51e-25 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 111.65 E-value: 4.51e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPqlhhniknGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:PRK11176 342 IEFRNVTFTYP--------GKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDI------------------ 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkeDSANIIrLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASVREMVI 1114
Cdd:PRK11176 396 ----------------------DEGEIL-LDGHDLRDYTLASLRNQVALVSQNVHLF-NDTIANNIAYARTEQYSREQIE 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 TSARVCRCESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMR 1190
Cdd:PRK11176 452 EAARMAYAMDFINKMDNGLDTVIGEngvlLSGGQRQRIAIARALLRD---SPILILDEATSALDTESERAIQAALDELQK 528
|
250 260
....*....|....*....|....*....
gi 1624762192 1191 ARggsTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK11176 529 NR---TSLVIAHRLSTIEKADEILVVEDG 554
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
982-1231 |
4.52e-25 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 105.32 E-value: 4.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANI 1061
Cdd:COG4555 19 DVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKP----------------------------------------DSGSI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 iRLDGIPIAcFSTTFLRKAFGILEQNPCVFENMTFFENISFFAdnaSVREMVItSARVCRCESFIKNHPLS--YDAPVGR 1139
Cdd:COG4555 59 -LIDGEDVR-KEPREARRQIGVLPDERGLYDRLTVRENIRYFA---ELYGLFD-EELKKRIEELIELLGLEefLDRRVGE 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRArgGSTAIIISHRPS-ALRLAGRVVLLgD 1218
Cdd:COG4555 133 LSTGMKKKVALARALVHDPK---VLLLDEPTNGLDVMARRLLREILRALKKE--GKTVLFSSHIMQeVEALCDRVVIL-H 206
|
250
....*....|...
gi 1624762192 1219 GGRSMYEGPPSGL 1231
Cdd:COG4555 207 KGKVVAQGSLDEL 219
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
982-1229 |
4.99e-25 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 105.51 E-value: 4.99e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:COG1120 19 DVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKP-----------------------------------------SSGE 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTFLRKAFGILEQNPCVFENMTFFENIS---------FFADNASVREMVITSARVCRCESFIknhpls 1132
Cdd:COG1120 58 VLLDGRDLASLSRRELARRIAYVPQEPPAPFGLTVRELVAlgryphlglFGRPSAEDREAVEEALERTGLEHLA------ 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 yDAPVGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLD-GHSegcVE--EALAEFMRARGGsTAIIISHRPS-ALR 1208
Cdd:COG1120 132 -DRPVDELSGGERQRVLIARALAQ---EPPLLLLDEPTSHLDlAHQ---LEvlELLRRLARERGR-TVVMVLHDLNlAAR 203
|
250 260
....*....|....*....|.
gi 1624762192 1209 LAGRVVLLgDGGRSMYEGPPS 1229
Cdd:COG1120 204 YADRLVLL-KDGRIVAQGPPE 223
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
954-1219 |
2.19e-24 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 109.53 E-value: 2.19e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 954 SIDFYQVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmN 1033
Cdd:PRK11160 338 SLTLNNVSFTYPDQPQPV--------LKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDP----------------Q 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 CEElinifrycylelslplpnkedsaniIRLDGIPIACFSTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASVREMV 1113
Cdd:PRK11160 394 QGE-------------------------ILLNGQPIADYSEAALRQAISVVSQRVHLF-SATLRDNLLLAAPNASDEALI 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 ITSARVcRCESFIKN-HPLsyDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEF 1188
Cdd:PRK11160 448 EVLQQV-GLEKLLEDdKGL--NAWLGeggrQLSGGEQRRLGIARALLHD---APLLLLDEPTEGLDAETERQILELLAEH 521
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1189 MRargGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK11160 522 AQ---NKTVLMITHRLTGLEQFDRICVMDNG 549
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
955-1228 |
3.71e-24 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 102.41 E-value: 3.71e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHnikngslmlTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:COG1122 1 IELENLSFSYPGGTP---------ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKP------------------ 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPcvfENMTF----FENISF----FA-D 1105
Cdd:COG1122 54 -----------------------TSGEVLVDGKDITKKNLRELRRKVGLVFQNP---DDQLFaptvEEDVAFgpenLGlP 107
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1106 NASVREMVITSARVCRCESFiknhplsYDAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEAL 1185
Cdd:COG1122 108 REEIRERVEEALELVGLEHL-------ADRPPHELSGGQKQRVAIAGVLA---MEPEVLVLDEPTAGLDPRGRRELLELL 177
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1624762192 1186 AEFmrARGGSTAIIISHRPS-ALRLAGRVVLLgDGGRSMYEGPP 1228
Cdd:COG1122 178 KRL--NKEGKTVIIVTHDLDlVAELADRVIVL-DDGRIVADGTP 218
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
986-1171 |
4.49e-24 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 99.64 E-value: 4.49e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 986 KFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLD 1065
Cdd:pfam00005 7 TLNPGEILALVGPNGAGKSTLLKLIAGLLSP-----------------------------------------TEGTILLD 45
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1066 GIPIACFSTTFLRKAFGILEQNPCVFENMTFFENISFFADNASVREMVITSarvcRCESFIKNHPLSYDA------PVGR 1139
Cdd:pfam00005 46 GQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENLRLGLLLKGLSKREKDA----RAEEALEKLGLGDLAdrpvgeRPGT 121
|
170 180 190
....*....|....*....|....*....|..
gi 1624762192 1140 LSAGERQRLALARALVSsraGSGLFLLDEPTA 1171
Cdd:pfam00005 122 LSGGQRQRVAIARALLT---KPKLLLLDEPTA 150
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
980-1221 |
2.41e-22 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 94.62 E-value: 2.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:cd00267 15 LDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKP-----------------------------------------TS 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTTFLRKAFGILEQnpcvfenmtffenisffadnasvremvitsarvcrcesfiknhplsydapvgr 1139
Cdd:cd00267 54 GEILIDGKDIAKLPLEELRRRIGYVPQ----------------------------------------------------- 80
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALVSSRagsGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:cd00267 81 LSGGQRQRVALARALLLNP---DLLLLDEPTSGLDPASRERLLELLREL--AEEGRTVIIVTHDPELAELAADRVIVLKD 155
|
..
gi 1624762192 1220 GR 1221
Cdd:cd00267 156 GK 157
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
988-1204 |
6.96e-22 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 101.28 E-value: 6.96e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLDGI 1067
Cdd:TIGR02868 359 PPGERVAILGPSGSGKSTLLATLAGLLDP-----------------------------------------LQGEVTLDGV 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASVREMVITSARVcRCESFIKNHPLSYDAPVG----RLSAG 1143
Cdd:TIGR02868 398 PVSSLDQDEVRRRVSVCAQDAHLFDT-TVRENLRLARPDATDEELWAALERV-GLADWLRALPDGLDTVLGeggaRLSGG 475
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1624762192 1144 ERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEgcvEEALAEFMRARGGSTAIIISHRP 1204
Cdd:TIGR02868 476 ERQRLALARALL---ADAPILLLDEPTEHLDAETA---DELLEDLLAALSGRTVVLITHHL 530
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
954-1219 |
8.02e-22 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 95.25 E-value: 8.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 954 SIDFYQVCFVYPQlhhnikngSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDenfnnmiwm 1032
Cdd:cd03244 2 DIEFKNVSLRYRP--------NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSgSILID--------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1033 nceelinifrycylelslplpnkedsaniirldGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFadNASVREM 1112
Cdd:cd03244 65 ---------------------------------GVDISKIGLHDLRSRISIIPQDPVLFSG-TIRSNLDPF--GEYSDEE 108
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1113 VITSARVCRCESFIKNHPLSYDAPV----GRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEF 1188
Cdd:cd03244 109 LWQALERVGLKEFVESLPGGLDTVVeeggENLSVGQRQLLCLARALLRK---SKILVLDEATASVDPETDALIQKTIREA 185
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1189 MRargGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:cd03244 186 FK---DCTVLTIAHRLDTIIDSDRILVLDKG 213
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
959-1219 |
1.69e-21 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 94.07 E-value: 1.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 959 QVCFVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYdpvrtikidenfnnmiwmnceeli 1038
Cdd:cd03225 4 NLSFSYPDGARPA--------LDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLL------------------------ 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1039 nifrycylelslplpnKEDSANIiRLDGIPIACFSTTFLRKAFGILEQNPcvfENM----TFFENISFFADNAS-----V 1109
Cdd:cd03225 52 ----------------GPTSGEV-LVDGKDLTKLSLKELRRKVGLVFQNP---DDQffgpTVEEEVAFGLENLGlpeeeI 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1110 REMVITSARVCRCESFiKNHPLSydapvgRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEFm 1189
Cdd:cd03225 112 EERVEEALELVGLEGL-RDRSPF------TLSGGQKQRVAIAGVLA---MDPDILLLDEPTAGLDPAGRRELLELLKKL- 180
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1190 rARGGSTAIIISHRPS-ALRLAGRVVLLGDG 1219
Cdd:cd03225 181 -KAEGKTIIIVTHDLDlLLELADRVIVLEDG 210
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
980-1219 |
3.87e-21 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 91.86 E-value: 3.87e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSA 1059
Cdd:cd03229 16 LNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEP----------------------------------------DSG 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIiRLDGIPIA--CFSTTFLRKAFGILEQNPCVFENMTFFENISFfadnasvremvitsarvcrcesfiknhplsydapv 1137
Cdd:cd03229 56 SI-LIDGEDLTdlEDELPPLRRRIGMVFQDFALFPHLTVLENIAL----------------------------------- 99
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1138 gRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPS-ALRLAGRVVLL 1216
Cdd:cd03229 100 -GLSGGQQQRVALARALAMD---PDVLLLDEPTSALDPITRREVRALLKS-LQAQLGITVVLVTHDLDeAARLADRVVVL 174
|
...
gi 1624762192 1217 GDG 1219
Cdd:cd03229 175 RDG 177
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
982-1231 |
4.79e-21 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 93.59 E-value: 4.79e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAkfRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:COG1131 20 SLTV--EPGEIFGLLGPNGAGKTTTIRMLLGLLRP-----------------------------------------TSGE 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTfLRKAFGILEQNPCVFENMTFFENISFFA-----DNASVREMVITSARVCRCESFIknhplsyDAP 1136
Cdd:COG1131 57 VRVLGEDVARDPAE-VRRRIGYVPQEPALYPDLTVRENLRFFArlyglPRKEARERIDELLELFGLTDAA-------DRK 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 VGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSegcvEEALAEFMR--ARGGSTAIIISHRPS-ALRLAGRV 1213
Cdd:COG1131 129 VGTLSGGMKQRLGLALALLHDPE---LLILDEPTSGLDPEA----RRELWELLRelAAEGKTVLLSTHYLEeAERLCDRV 201
|
250
....*....|....*...
gi 1624762192 1214 VLLgDGGRSMYEGPPSGL 1231
Cdd:COG1131 202 AII-DKGRIVADGTPDEL 218
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
982-1229 |
8.10e-21 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 92.89 E-value: 8.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmncEELINifrycylelsLPlPNKedsan 1060
Cdd:cd03219 18 DVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSgSVLFDG----------EDITG----------LP-PHE----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1061 IIRLdGIpiacfSTTFlrkafgileQNPCVFENMTFFENI---------SFFADNASVREMVITSARVCRCESFIKNHPL 1131
Cdd:cd03219 72 IARL-GI-----GRTF---------QIPRLFPELTVLENVmvaaqartgSGLLLARARREEREARERAEELLERVGLADL 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1132 SyDAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLdGHSEgcvEEALAEFMR--ARGGSTAIIISHR-PSALR 1208
Cdd:cd03219 137 A-DRPAGELSYGQQRRLEIARALA---TDPKLLLLDEPAAGL-NPEE---TEELAELIRelRERGITVLLVEHDmDVVMS 208
|
250 260
....*....|....*....|.
gi 1624762192 1209 LAGRVVLLgDGGRSMYEGPPS 1229
Cdd:cd03219 209 LADRVTVL-DQGRVIAEGTPD 228
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
980-1228 |
2.00e-20 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 91.79 E-value: 2.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSA 1059
Cdd:cd03261 16 LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRP----------------------------------------DSG 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIiRLDGIPIACFSTTFL---RKAFGILEQNPCVFENMTFFENISFFadnasVREMVITSARVCR-----------CESF 1125
Cdd:cd03261 56 EV-LIDGEDISGLSEAELyrlRRRMGMLFQSGALFDSLTVFENVAFP-----LREHTRLSEEEIReivlekleavgLRGA 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1126 IKNHPlsydapvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHR-P 1204
Cdd:cd03261 130 EDLYP-------AELSGGMKKRVALARALALD---PELLLYDEPTAGLDPIASGVIDDLIRS-LKKELGLTSIMVTHDlD 198
|
250 260
....*....|....*....|....
gi 1624762192 1205 SALRLAGRVVLLGDgGRSMYEGPP 1228
Cdd:cd03261 199 TAFAIADRIAVLYD-GKIVAEGTP 221
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
982-1220 |
5.69e-20 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 88.65 E-value: 5.69e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:cd03214 17 DLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKP-----------------------------------------SSGE 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTFLRKAFGILEQnpcVFENMtffeNISFFADnasvremvitsarvcRcesfiknhplsydaPVGRLS 1141
Cdd:cd03214 56 ILLDGKDLASLSPKELARKIAYVPQ---ALELL----GLAHLAD---------------R--------------PFNELS 99
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1142 AGERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGsTAIIISHRPS-ALRLAGRVVLLGDGG 1220
Cdd:cd03214 100 GGERQRVLLARALAQ---EPPILLLDEPTSHLDIAHQIELLELLRRLARERGK-TVVMVLHDLNlAARYADRVILLKDGR 175
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
955-1226 |
7.51e-20 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 88.14 E-value: 7.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYP-QLHHNIKNGSLMLtlydftakfRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmn 1033
Cdd:cd03247 1 LSINNVSFSYPeQEQQVLKNLSLEL---------KQGEKIALLGRSGSGKSTLLQLLTGDLKP----------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 ceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTfLRKAFGILEQNPCVFeNMTFFENISFfadnasvremv 1113
Cdd:cd03247 55 ------------------------QQGEITLDGVPVSDLEKA-LSSLISVLNQRPYLF-DTTLRNNLGR----------- 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 itsarvcrcesfiknhplsydapvgRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRarg 1193
Cdd:cd03247 98 -------------------------RFSGGERQRLALARILLQD---APIVLLDEPTVGLDPITERQLLSLIFEVLK--- 146
|
250 260 270
....*....|....*....|....*....|...
gi 1624762192 1194 GSTAIIISHRPSALRLAGRVVLLgDGGRSMYEG 1226
Cdd:cd03247 147 DKTLIWITHHLTGIEHMDKILFL-ENGKIIMQG 178
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
955-1219 |
1.94e-19 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 88.32 E-value: 1.94e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIKngslmlTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQ------ALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRP------------------ 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTT----FLRKAFGILEQNPCVFENMTFFENIS----FFADN 1106
Cdd:cd03255 57 -----------------------TSGEVRVDGTDISKLSEKelaaFRRRHIGFVFQSFNLLPDLTALENVElpllLAGVP 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1107 ASVREMVITSA--RVCrcesfIKNHplsYDAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEA 1184
Cdd:cd03255 114 KKERRERAEELleRVG-----LGDR---LNHYPSELSGGQQQRVAIARALANDPK---IILADEPTGNLDSETGKEVMEL 182
|
250 260 270
....*....|....*....|....*....|....*
gi 1624762192 1185 LAEFMRARgGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:cd03255 183 LRELNKEA-GTTIVVVTHDPELAEYADRIIELRDG 216
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
988-1228 |
1.31e-18 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 90.73 E-value: 1.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMydpvrtikidenfnnmiwmnceelinifrycylelslpLPNKEDSANIIRLDGI 1067
Cdd:COG1123 30 APGETVALVGESGSGKSTLALALMGL--------------------------------------LPHGGRISGEVLLDGR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFLRKAFGILEQNPCVFENM-TFFENISFFADNASV-----REMVITSARVCRCESFIKNHPlsydapvGRLS 1141
Cdd:COG1123 72 DLLELSEALRGRRIGMVFQDPMTQLNPvTVGDQIAEALENLGLsraeaRARVLELLEAVGLERRLDRYP-------HQLS 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1142 AGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPS-ALRLAGRVVLLgDGG 1220
Cdd:COG1123 145 GGQRQRVAIAMALA---LDPDLLIADEPTTALDVTTQAEILDLLRE-LQRERGTTVLLITHDLGvVAEIADRVVVM-DDG 219
|
....*...
gi 1624762192 1221 RSMYEGPP 1228
Cdd:COG1123 220 RIVEDGPP 227
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
966-1219 |
2.67e-18 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 85.10 E-value: 2.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 966 QLHHNIKNGSLMLT-LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifryc 1044
Cdd:COG1136 9 NLTKSYGTGEGEVTaLRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRP---------------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1045 ylelslplpnkedSANIIRLDGIPIACFS----TTFLRKAFGILEQNPCVFENMTFFENI---------SFFADNASVRE 1111
Cdd:COG1136 61 -------------TSGEVLIDGQDISSLSerelARLRRRHIGFVFQFFNLLPELTALENValplllagvSRKERRERARE 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1112 MVitsARVcRCESFIKNHPlsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRA 1191
Cdd:COG1136 128 LL---ERV-GLGDRLDHRP-------SQLSGGQQQRVAIARALVNRPK---LILADEPTGNLDSKTGEEVLELLRE-LNR 192
|
250 260
....*....|....*....|....*...
gi 1624762192 1192 RGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:COG1136 193 ELGTTIVMVTHDPELAARADRVIRLRDG 220
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
980-1219 |
7.28e-18 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 83.50 E-value: 7.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFT--AKFRA-GEITALIGETGSGKSTIMRLLKRMYDPVR-TIKidenFNNMIWMNCEELINifrycylelslpLPNK 1055
Cdd:cd03297 10 LPDFTlkIDFDLnEEVTGIFGASGAGKSTLLRCIAGLEKPDGgTIV----LNGTVLFDSRKKIN------------LPPQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1056 edsaniirldgipiacfsttflRKAFGILEQNPCVFENMTFFENISFFADNASVREMVITSARVCrcESFIKNHPLsyDA 1135
Cdd:cd03297 74 ----------------------QRKIGLVFQQYALFPHLNVRENLAFGLKRKRNREDRISVDELL--DLLGLDHLL--NR 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1136 PVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPS-ALRLAGRVV 1214
Cdd:cd03297 128 YPAQLSGGEKQRVALARALAAQPE---LLLLDEPFSALDRALRLQLLPELKQ-IKKNLNIPVIFVTHDLSeAEYLADRIV 203
|
....*
gi 1624762192 1215 LLGDG 1219
Cdd:cd03297 204 VMEDG 208
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
980-1219 |
8.09e-18 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 86.67 E-value: 8.09e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmnceELINifrycylelSLPlPNKEDs 1058
Cdd:COG3839 19 LKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSgEILIGG-----------RDVT---------DLP-PKDRN- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1059 aniirldgipIA-CFsttflrkafgileQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPls 1132
Cdd:COG3839 77 ----------IAmVF-------------QSYALYPHMTVYENIAFplklrKVPKAEIDRRVREAAELLGLEDLLDRKP-- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 ydapvGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHsegcveeaLAEFMRA-------RGGSTAIIISHRPS 1205
Cdd:COG3839 132 -----KQLSGGQRQRVALGRALV---REPKVFLLDEPLSNLDAK--------LRVEMRAeikrlhrRLGTTTIYVTHDQV 195
|
250
....*....|....*
gi 1624762192 1206 -ALRLAGRVVLLGDG 1219
Cdd:COG3839 196 eAMTLADRIAVMNDG 210
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
988-1219 |
8.64e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 88.75 E-value: 8.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTimrllkrmydpvrtikidenfnnmiwmnceeLINIfrycyleLSLPLPNKEDsaniIRLDGI 1067
Cdd:PRK11174 374 PAGQRIALVGPSGAGKTS-------------------------------LLNA-------LLGFLPYQGS----LKINGI 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASVRE--MVITSARVcrcESFIKNHPLSYDAPVG----RLS 1141
Cdd:PRK11174 412 ELRELDPESWRKHLSWVGQNPQLPHG-TLRDNVLLGNPDASDEQlqQALENAWV---SEFLPLLPQGLDTPIGdqaaGLS 487
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1624762192 1142 AGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRargGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK11174 488 VGQAQRLALARALLQP---CQLLLLDEPTASLDAHSEQLVMQALNAASR---RQTTLMVTHQLEDLAQWDQIWVMQDG 559
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
952-1219 |
3.25e-17 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 86.70 E-value: 3.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 952 SKSIDFYQVCFVYpqlhhniKNGSLMLTLYDFTAKFRAgeITALIGETGSGKSTIMRLLKRMYdpvrtikidenfnnmiw 1031
Cdd:PRK10790 338 SGRIDIDNVSFAY-------RDDNLVLQNINLSVPSRG--FVALVGHTGSGKSTLASLLMGYY----------------- 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1032 mnceelinifrycylelslPLPNKEdsaniIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNAsvRE 1111
Cdd:PRK10790 392 -------------------PLTEGE-----IRLDGRPLSSLSHSVLRQGVAMVQQDPVVLAD-TFLANVTLGRDIS--EE 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1112 MVITSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAE 1187
Cdd:PRK10790 445 QVWQALETVQLAELARSLPDGLYTPLGeqgnNLSVGQKQLLALARVLVQTPQ---ILILDEATANIDSGTEQAIQQALAA 521
|
250 260 270
....*....|....*....|....*....|..
gi 1624762192 1188 FmraRGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK10790 522 V---REHTTLVVIAHRLSTIVEADTILVLHRG 550
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
982-1219 |
3.38e-17 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 86.23 E-value: 3.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANI 1061
Cdd:COG1129 24 SLE--LRPGEVHALLGENGAGKSTLMKILSGVYQP----------------------------------------DSGEI 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 iRLDGIPIAcFSTTFLRKAFGI--LEQNPCVFENMTFFENIsfFADNASVREMVITSARVCR-----CESFikNHPLSYD 1134
Cdd:COG1129 62 -LLDGEPVR-FRSPRDAQAAGIaiIHQELNLVPNLSVAENI--FLGREPRRGGLIDWRAMRRrarelLARL--GLDIDPD 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 APVGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDGHsegcvE-EALAEFMR---ARGgsTAII-ISHR-PSALR 1208
Cdd:COG1129 136 TPVGDLSVAQQQLVEIARALSR---DARVLILDEPTASLTER-----EvERLFRIIRrlkAQG--VAIIyISHRlDEVFE 205
|
250
....*....|.
gi 1624762192 1209 LAGRVVLLGDG 1219
Cdd:COG1129 206 IADRVTVLRDG 216
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
979-1219 |
3.60e-17 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 81.53 E-value: 3.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 979 TLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDENFNNMiwmnceelinifrycylelsLPlPNKED 1057
Cdd:cd03301 15 ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSgRIYIGGRDVTD--------------------LP-PKDRD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 SANIIrldgipiacfsttflrkafgileQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPls 1132
Cdd:cd03301 74 IAMVF-----------------------QNYALYPHMTVYDNIAFglklrKVPKDEIDERVREVAELLQIEHLLDRKP-- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 ydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEgcvEEALAEFMR--ARGGSTAIIISH-RPSALRL 1209
Cdd:cd03301 129 -----KQLSGGQRQRVALGRAIVREPK---VFLMDEPLSNLDAKLR---VQMRAELKRlqQRLGTTTIYVTHdQVEAMTM 197
|
250
....*....|
gi 1624762192 1210 AGRVVLLGDG 1219
Cdd:cd03301 198 ADRIAVMNDG 207
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
955-1219 |
6.02e-17 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 81.25 E-value: 6.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIKNGSLmltlydftaKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmn 1033
Cdd:COG2884 2 IRFENVSKRYPGGREALSDVSL---------EIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSgQVLVNG--------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 ceelINIFRycylelslpLPNKEdsaniirldgIPiacfsttFLRKAFGILEQNPCVFENMTFFENISFFadnasvreMV 1113
Cdd:COG2884 64 ----QDLSR---------LKRRE----------IP-------YLRRRIGVVFQDFRLLPDRTVYENVALP--------LR 105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 ITSARvcrcESFIKNH-P-------LS--YDAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDghsegcvEE 1183
Cdd:COG2884 106 VTGKS----RKEIRRRvRevldlvgLSdkAKALPHELSGGEQQRVAIARALVNRPE---LLLADEPTGNLD-------PE 171
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1624762192 1184 ALAEFMRA-----RGGSTAIIISHRPSAL-RLAGRVVLLGDG 1219
Cdd:COG2884 172 TSWEIMELleeinRRGTTVLIATHDLELVdRMPKRVLELEDG 213
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
982-1228 |
1.01e-16 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 81.18 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKID-ENFNNMiwmNCEELINIfrycylelslplpnkedsa 1059
Cdd:COG1127 23 GVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSgEILVDgQDITGL---SEKELYEL------------------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 niirldgipiacfsttflRKAFGILEQNPCVFENMTFFENISFF------ADNASVREMVITS-ARVcRCESFIKNHPls 1132
Cdd:COG1127 81 ------------------RRRIGMLFQGGALFDSLTVFENVAFPlrehtdLSEAEIRELVLEKlELV-GLPGAADKMP-- 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 ydapvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHR-PSALRLAG 1211
Cdd:COG1127 140 -----SELSGGMRKRVALARALALD---PEILLYDEPTAGLDPITSAVIDELIRE-LRDELGLTSVVVTHDlDSAFAIAD 210
|
250
....*....|....*..
gi 1624762192 1212 RVVLLGDgGRSMYEGPP 1228
Cdd:COG1127 211 RVAVLAD-GKIIAEGTP 226
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
982-1226 |
1.31e-16 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 80.10 E-value: 1.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:cd03266 25 SFTVK--PGEVTGLLGPNGAGKTTTLRMLAGLLEP-----------------------------------------DAGF 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGI-----PIAcfsttfLRKAFGILEQNPCVFENMTFFENISFFAD---------NASVREMvitsARVCRCESFIk 1127
Cdd:cd03266 62 ATVDGFdvvkePAE------ARRRLGFVSDSTGLYDRLTARENLEYFAGlyglkgdelTARLEEL----ADRLGMEELL- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1128 nhplsyDAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSegcvEEALAEFMRA--RGGSTAIIISHRPS 1205
Cdd:cd03266 131 ------DRRVGGFSTGMRQKVAIARALVHD---PPVLLLDEPTTGLDVMA----TRALREFIRQlrALGKCILFSTHIMQ 197
|
250 260
....*....|....*....|..
gi 1624762192 1206 -ALRLAGRVVLLGDgGRSMYEG 1226
Cdd:cd03266 198 eVERLCDRVVVLHR-GRVVYEG 218
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
978-1219 |
1.46e-16 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 79.61 E-value: 1.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 978 LTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDENfnnmiwmnceelinifrycylelslPLPNKE 1056
Cdd:cd03226 14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSgSILLNGK-------------------------PIKAKE 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1057 dsaniirldgipiacfsttfLRKAFGILEQNPcvfeNMTFFENisffadnaSVREMVI-----TSARVCRCESFIKN--- 1128
Cdd:cd03226 69 --------------------RRKSIGYVMQDV----DYQLFTD--------SVREELLlglkeLDAGNEQAETVLKDldl 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1129 ------HPLSydapvgrLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSegcvEEALAEFMR--ARGGSTAIII 1200
Cdd:cd03226 117 yalkerHPLS-------LSGGQKQRLAIAAALLSGKD---LLIFDEPTSGLDYKN----MERVGELIRelAAQGKAVIVI 182
|
250 260
....*....|....*....|
gi 1624762192 1201 SHRPS-ALRLAGRVVLLGDG 1219
Cdd:cd03226 183 THDYEfLAKVCDRVLLLANG 202
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
979-1219 |
1.81e-16 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 80.59 E-value: 1.81e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 979 TLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYD--PVRTIKIDENFNNMiwmnceeliNIFRycylelslplPNKE 1056
Cdd:PRK14239 20 ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDlnPEVTITGSIVYNGH---------NIYS----------PRTD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1057 dsaniirldgipiacfsTTFLRKAFGILEQNPCVFEnMTFFENISF------FADNASVREMVITSARVCRCESFIKNHp 1130
Cdd:PRK14239 81 -----------------TVDLRKEIGMVFQQPNPFP-MSIYENVVYglrlkgIKDKQVLDEAVEKSLKGASIWDEVKDR- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 lSYDAPVGrLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmraRGGSTAIIISHR-PSALRL 1209
Cdd:PRK14239 142 -LHDSALG-LSGGQQQRVCIARVLATS---PKIILLDEPTSALDPISAGKIEETLLGL---KDDYTMLLVTRSmQQASRI 213
|
250
....*....|
gi 1624762192 1210 AGRVVLLGDG 1219
Cdd:PRK14239 214 SDRTGFFLDG 223
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
980-1219 |
2.16e-16 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 78.21 E-value: 2.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:cd03230 16 LDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKP-----------------------------------------DS 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIAcFSTTFLRKAFGILEQNPCVFENMTFFENIsffadnasvremvitsarvcrcesfiknhplsydapvgR 1139
Cdd:cd03230 55 GEIKVLGKDIK-KEPEEVKRRIGYLPEEPSLYENLTVRENL--------------------------------------K 95
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD--GHSEgcVEEALAEFmrARGGSTAIIISHRPS-ALRLAGRVVLL 1216
Cdd:cd03230 96 LSGGMKQRLALAQALLHDPE---LLILDEPTSGLDpeSRRE--FWELLREL--KKEGKTILLSSHILEeAERLCDRVAIL 168
|
...
gi 1624762192 1217 GDG 1219
Cdd:cd03230 169 NNG 171
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
982-1229 |
2.70e-16 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 83.41 E-value: 2.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:COG1123 285 SLT--LRRGETLGLVGESGSGKSTLARLLLGLLRP-----------------------------------------TSGS 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFS---TTFLRKAFGILEQNP--CVFENMTFFENISFFADN------ASVREMVITSARVCR-CESFIKNH 1129
Cdd:COG1123 322 ILFDGKDLTKLSrrsLRELRRRVQMVFQDPysSLNPRMTVGDIIAEPLRLhgllsrAERRERVAELLERVGlPPDLADRY 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1130 PlsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPS-ALR 1208
Cdd:COG1123 402 P-------HELSGGQRQRVAIARALALEPK---LLILDEPTSALDVSVQAQILNLLRD-LQRELGLTYLFISHDLAvVRY 470
|
250 260
....*....|....*....|.
gi 1624762192 1209 LAGRVVLLgDGGRSMYEGPPS 1229
Cdd:COG1123 471 IADRVAVM-YDGRIVEDGPTE 490
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
982-1228 |
3.67e-16 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 79.70 E-value: 3.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:COG0411 22 DVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRP-----------------------------------------TSGR 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFST----------TFlrkafgileQNPCVFENMTFFENI--------------SFFADNASVREMVITSA 1117
Cdd:COG0411 61 ILFDGRDITGLPPhriarlgiarTF---------QNPRLFPELTVLENVlvaaharlgrgllaALLRLPRARREEREARE 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1118 RVCRCESFIKNHPLSyDAPVGRLSAGERQRLALARALVSS-RagsgLFLLDEPTAHLdGHSEGcveEALAEF---MRARG 1193
Cdd:COG0411 132 RAEELLERVGLADRA-DEPAGNLSYGQQRRLEIARALATEpK----LLLLDEPAAGL-NPEET---EELAELirrLRDER 202
|
250 260 270
....*....|....*....|....*....|....*.
gi 1624762192 1194 GSTAIIISHRPSAL-RLAGRVVLLgDGGRSMYEGPP 1228
Cdd:COG0411 203 GITILLIEHDMDLVmGLADRIVVL-DFGRVIAEGTP 237
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
980-1231 |
3.75e-16 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 79.53 E-value: 3.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSA 1059
Cdd:cd03256 17 LKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEP----------------------------------------TSG 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIrLDGIPIACFSTTFLRKA---FGILEQNPCVFENMTFFENI--SFFADNASVREMV--ITSARVCRCESFIKNHPLS 1132
Cdd:cd03256 57 SVL-IDGTDINKLKGKALRQLrrqIGMIFQQFNLIERLSVLENVlsGRLGRRSTWRSLFglFPKEEKQRALAALERVGLL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 YDA--PVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARgGSTAIIISHRPS-ALRL 1209
Cdd:cd03256 136 DKAyqRADQLSGGQQQRVAIARALMQQ---PKLILADEPVASLDPASSRQVMDLLKRINREE-GITVIVSLHQVDlAREY 211
|
250 260
....*....|....*....|..
gi 1624762192 1210 AGRVVLLGDgGRSMYEGPPSGL 1231
Cdd:cd03256 212 ADRIVGLKD-GRIVFDGPPAEL 232
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
982-1229 |
6.21e-16 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 82.38 E-value: 6.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANI 1061
Cdd:COG3845 25 SLT--VRPGEIHALLGENGAGKSTLMKILYGLYQP----------------------------------------DSGEI 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 iRLDGIPIACFSTTFLRKAfGI--LEQNPCVFENMTFFENI--------SFFADNASVREMVitsarvcrcESFIKNHPL 1131
Cdd:COG3845 63 -LIDGKPVRIRSPRDAIAL-GIgmVHQHFMLVPNLTVAENIvlgleptkGGRLDRKAARARI---------RELSERYGL 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1132 SYD--APVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHsEgcVEEaLAEFMR--ARGGSTAIIISHR-PSA 1206
Cdd:COG3845 132 DVDpdAKVEDLSVGEQQRVEILKALY---RGARILILDEPTAVLTPQ-E--ADE-LFEILRrlAAEGKSIIFITHKlREV 204
|
250 260
....*....|....*....|...
gi 1624762192 1207 LRLAGRVVLLgDGGRSMYEGPPS 1229
Cdd:COG3845 205 MAIADRVTVL-RRGKVVGTVDTA 226
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
955-1219 |
7.06e-16 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 77.83 E-value: 7.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPqlhHNIKngslmlTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03292 1 IEFINVTKTYP---NGTA------ALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELP------------------ 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACF---STTFLRKAFGILEQNPCVFENMTFFENISF-----FADN 1106
Cdd:cd03292 54 -----------------------TSGTIRVNGQDVSDLrgrAIPYLRRKIGVVFQDFRLLPDRNVYENVAFalevtGVPP 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1107 ASVREMVITSARVCRCESFIKNHPlsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALA 1186
Cdd:cd03292 111 REIRKRVPAALELVGLSHKHRALP-------AELSGGEQQRVAIARAIVNSPT---ILIADEPTGNLDPDTTWEIMNLLK 180
|
250 260 270
....*....|....*....|....*....|....
gi 1624762192 1187 EFMRArgGSTAIIISHRPSAL-RLAGRVVLLGDG 1219
Cdd:cd03292 181 KINKA--GTTVVVATHAKELVdTTRHRVIALERG 212
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
980-1216 |
1.02e-15 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 77.19 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceelinifrycyLELslpLPNKEDSa 1059
Cdd:cd03235 15 LEDVSFEVKPGEFLAIVGPNGAGKSTLLKAI-----------------------------------LGL---LKPTSGS- 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 niIRLDGIPIACFsttflRKAFGILEQNP--------CVFE--NMTFFENISFF-----ADNASVRE---MVITSArvcr 1121
Cdd:cd03235 56 --IRVFGKPLEKE-----RKRIGYVPQRRsidrdfpiSVRDvvLMGLYGHKGLFrrlskADKAKVDEaleRVGLSE---- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1122 cesfIKNHPLsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARgGSTAIIIS 1201
Cdd:cd03235 125 ----LADRQI------GELSGGQQQRVLLARALVQDPD---LLLLDEPFAGVDPKTQEDIYELLRE-LRRE-GMTILVVT 189
|
250
....*....|....*.
gi 1624762192 1202 H-RPSALRLAGRVVLL 1216
Cdd:cd03235 190 HdLGLVLEYFDRVLLL 205
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
987-1229 |
1.04e-15 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 78.27 E-value: 1.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 987 FRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnCEELinifrycylelslplpnkEDSANIIRLDG 1066
Cdd:PRK13548 25 LRPGEVVAILGPNGAGKSTLLRAL-----------------------SGEL------------------SPDSGEVRLNG 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 IPIACFSTTFLRKAFGILEQNPcvfeNMTFfeniSFfadnaSVREmVITSARVCRCESFIKNHPL--SYDAPVG------ 1138
Cdd:PRK13548 64 RPLADWSPAELARRRAVLPQHS----SLSF----PF-----TVEE-VVAMGRAPHGLSRAEDDALvaAALAQVDlahlag 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 ----RLSAGERQRLALARAL--VSSRAGS-GLFLLDEPTAHLD-GHSEGCVeEALAEFMRARGGsTAIIISHRPS-ALRL 1209
Cdd:PRK13548 130 rdypQLSGGEQQRVQLARVLaqLWEPDGPpRWLLLDEPTSALDlAHQHHVL-RLARQLAHERGL-AVIVVLHDLNlAARY 207
|
250 260
....*....|....*....|
gi 1624762192 1210 AGRVVLLgDGGRSMYEGPPS 1229
Cdd:PRK13548 208 ADRIVLL-HQGRLVADGTPA 226
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
986-1219 |
1.54e-15 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 75.54 E-value: 1.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 986 KFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANIiRLD 1065
Cdd:cd03216 22 SVRRGEVHALLGENGAGKSTLMKILSGLYKP----------------------------------------DSGEI-LVD 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1066 GIPIAcFSTTFLRKAFGIleqnpcvfenmtffenisffadnasvrEMVitsarvcrcesfiknHplsydapvgRLSAGER 1145
Cdd:cd03216 61 GKEVS-FASPRDARRAGI---------------------------AMV---------------Y---------QLSVGER 88
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1624762192 1146 QRLALARALVSsraGSGLFLLDEPTAHLDGHsegcvE-EALAEFMR--ARGGSTAIIISHRPS-ALRLAGRVVLLGDG 1219
Cdd:cd03216 89 QMVEIARALAR---NARLLILDEPTAALTPA-----EvERLFKVIRrlRAQGVAVIFISHRLDeVFEIADRVTVLRDG 158
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
955-1219 |
1.95e-15 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 77.34 E-value: 1.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQLHHNIKNGSLmltlydftaKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:cd03295 1 IEFENVTKRYGGGKKAVNNLNL---------EIAKGEFLVLIGPSGSGKTTTMKMINRLIEP------------------ 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENMTFFENISFFADNASVREMVI 1114
Cdd:cd03295 54 -----------------------TSGEIFIDGEDIREQDPVELRRKIGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKI 110
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1115 tSARVCRCESFIKNHPLSY-DAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEalaEFMR--A 1191
Cdd:cd03295 111 -RERADELLALVGLDPAEFaDRYPHELSGGQQQRVGVARALA---ADPPLLLMDEPFGALDPITRDQLQE---EFKRlqQ 183
|
250 260
....*....|....*....|....*....
gi 1624762192 1192 RGGSTAIIISHR-PSALRLAGRVVLLGDG 1219
Cdd:cd03295 184 ELGKTIVFVTHDiDEAFRLADRIAIMKNG 212
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
980-1219 |
2.23e-15 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 76.99 E-value: 2.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVRtikidenfnNMIWMNCEELINifrycylelsLPlPNKEDsa 1059
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDS---------GKILLNGKDITN----------LP-PEKRD-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 niirldgipiacfsttflrkaFGILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPlsyd 1134
Cdd:cd03299 73 ---------------------ISYVPQNYALFPHMTVYKNIAYglkkrKVDKKEIERKVLEIAEMLGIDHLLNRKP---- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 apvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAeFMRARGGSTAIIISHRPS-ALRLAGRV 1213
Cdd:cd03299 128 ---ETLSGGEQQRVAIARALVVN---PKILLLDEPFSALDVRTKEKLREELK-KIRKEFGVTVLHVTHDFEeAWALADKV 200
|
....*.
gi 1624762192 1214 VLLGDG 1219
Cdd:cd03299 201 AIMLNG 206
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
982-1226 |
2.28e-15 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 76.38 E-value: 2.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETP-----------------------------------------QSGR 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTflRKAFGILEQNPCVFENMTFFENISFFAD-----NASVREMVITSARVCRCESFIKNHPlsydap 1136
Cdd:cd03298 55 VLINGVDVTAAPPA--DRPVSMLFQENNLFAHLTVEQNVGLGLSpglklTAEDRQAIEVALARVGLAGLEKRLP------ 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 vGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRARgGSTAIIISHRPS-ALRLAGRVVL 1215
Cdd:cd03298 127 -GELSGGERQRVALARVLVRDKP---VLLLDEPFAALDPALRAEMLDLVLDLHAET-KMTVLMVTHQPEdAKRLAQRVVF 201
|
250
....*....|.
gi 1624762192 1216 LgDGGRSMYEG 1226
Cdd:cd03298 202 L-DNGRIAAQG 211
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
980-1219 |
2.47e-15 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 76.99 E-value: 2.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVrtikidenfNNMIWMNceelinifrycylelslplpNKEDSA 1059
Cdd:cd03296 18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPD---------SGTILFG--------------------GEDATD 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIpiacfsttflrkafGILEQNPCVFENMTFFENISF---------FADNASVREMVITSARVCRCESFIKNHP 1130
Cdd:cd03296 69 VPVQERNV--------------GFVFQHYALFRHMTVFDNVAFglrvkprseRPPEAEIRAKVHELLKLVQLDWLADRYP 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 lsydapvGRLSAGERQRLALARAL-VSSRagsgLFLLDEPTAHLDGHsegcVEEALAEFMRA---RGGSTAIIISH-RPS 1205
Cdd:cd03296 135 -------AQLSGGQRQRVALARALaVEPK----VLLLDEPFGALDAK----VRKELRRWLRRlhdELHVTTVFVTHdQEE 199
|
250
....*....|....
gi 1624762192 1206 ALRLAGRVVLLGDG 1219
Cdd:cd03296 200 ALEVADRVVVMNKG 213
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
982-1226 |
4.85e-15 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 79.72 E-value: 4.85e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnCEELinifrycylelslplpnKEDSANI 1061
Cdd:COG0488 333 DLSLRIDRGDRIGLIGPNGAGKSTLLKLL-----------------------AGEL-----------------EPDSGTV 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFS--TTFLRkafgileqnpcvfENMTFFENISFFADNAsvREMVITSarvcRCESFIknhpLSYD---AP 1136
Cdd:COG0488 373 KLGETVKIGYFDqhQEELD-------------PDKTVLDELRDGAPGG--TEQEVRG----YLGRFL----FSGDdafKP 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 VGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEGCVEEALAEFmrarGGsTAIIISHRPSAL-RLAGRVVL 1215
Cdd:COG0488 430 VGVLSGGEKARLALAKLLLS---PPNVLLLDEPTNHLDIETLEALEEALDDF----PG-TVLLVSHDRYFLdRVATRILE 501
|
250
....*....|.
gi 1624762192 1216 LGDGGRSMYEG 1226
Cdd:COG0488 502 FEDGGVREYPG 512
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
982-1219 |
7.64e-15 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 77.45 E-value: 7.64e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmnceELINifrycylelSLPlPNKEDsan 1060
Cdd:COG3842 23 DVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSgRILLDG-----------RDVT---------GLP-PEKRN--- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1061 iirldgipiacfsttflrkaFGILEQNPCVFENMTFFENISFF--------AD-NASVREMVitsARVcRCESFIKNHPl 1131
Cdd:COG3842 79 --------------------VGMVFQDYALFPHLTVAENVAFGlrmrgvpkAEiRARVAELL---ELV-GLEGLADRYP- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1132 sydapvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGsTAIIISHRPS-ALRLA 1210
Cdd:COG3842 134 ------HQLSGGQQQRVALARALAPE---PRVLLLDEPLSALDAKLREEMREELRRLQRELGI-TFIYVTHDQEeALALA 203
|
....*....
gi 1624762192 1211 GRVVLLGDG 1219
Cdd:COG3842 204 DRIAVMNDG 212
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
980-1226 |
9.15e-15 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 74.12 E-value: 9.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLL--KRMYDPVRtikidenfnnmiwmnceelinifrycylelslplpnked 1057
Cdd:cd03213 25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALagRRTGLGVS--------------------------------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 saNIIRLDGIPIACFSttfLRKAFGILEQNPCVFENMTFFENISFfadnasvremvitSARvCRCesfiknhplsydapv 1137
Cdd:cd03213 66 --GEVLINGRPLDKRS---FRKIIGYVPQDDILHPTLTVRETLMF-------------AAK-LRG--------------- 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1138 grLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPSAL--RLAGRVVL 1215
Cdd:cd03213 112 --LSGGERKRVSIALELVSN---PSLLFLDEPTSGLDSSSALQVMSLLRRL--ADTGRTIICSIHQPSSEifELFDKLLL 184
|
250
....*....|.
gi 1624762192 1216 LGDgGRSMYEG 1226
Cdd:cd03213 185 LSQ-GRVIYFG 194
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
971-1210 |
9.69e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 74.53 E-value: 9.69e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 971 IKNGSLMLTLYDFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmnceelinifrycylels 1049
Cdd:PRK13539 11 VRGGRVLFSGLSFTLA--AGEALVLTGPNGSGKTTLLRLIAGLLPPAAgTIKLDG------------------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1050 lplpnkEDSaniirldGIPIACFSTTFLrkafGilEQNPCVfENMTFFENISFFADNASVREMVITSArVCrcesFIKNH 1129
Cdd:PRK13539 64 ------GDI-------DDPDVAEACHYL----G--HRNAMK-PALTVAENLEFWAAFLGGEELDIAAA-LE----AVGLA 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1130 PLSyDAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSegcvEEALAEFMRAR--GGSTAIIISHRPSAL 1207
Cdd:PRK13539 119 PLA-HLPFGYLSAGQKRRVALARLLVSNRP---IWILDEPTAALDAAA----VALFAELIRAHlaQGGIVIAATHIPLGL 190
|
...
gi 1624762192 1208 RLA 1210
Cdd:PRK13539 191 PGA 193
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
992-1227 |
1.00e-14 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 75.33 E-value: 1.00e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 992 ITALIGETGSGKSTIMRLLKRmydpvrtikidenfnnmiwmnceeLINIFrycylelslplPNKEDSANIIrLDGIPIAC 1071
Cdd:PRK14247 31 ITALMGPSGSGKSTLLRVFNR------------------------LIELY-----------PEARVSGEVY-LDGQDIFK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1072 FSTTFLRKAFGILEQNPCVFENMTFFENISF-------FADNASVREMVITSARVCRCESFIKNHplsYDAPVGRLSAGE 1144
Cdd:PRK14247 75 MDVIELRRRVQMVFQIPNPIPNLSIFENVALglklnrlVKSKKELQERVRWALEKAQLWDEVKDR---LDAPAGKLSGGQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1145 RQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEAlaeFMRARGGSTAIIISHRPS-ALRLAGRVVLLGdGGRSM 1223
Cdd:PRK14247 152 QQRLCIARALAFQ---PEVLLADEPTANLDPENTAKIESL---FLELKKDMTIVLVTHFPQqAARISDYVAFLY-KGQIV 224
|
....
gi 1624762192 1224 YEGP 1227
Cdd:PRK14247 225 EWGP 228
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
980-1217 |
1.27e-14 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 74.43 E-value: 1.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:cd03293 20 LEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERP-----------------------------------------TS 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIacfstTFLRKAFGILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPlsyd 1134
Cdd:cd03293 59 GEVLVDGEPV-----TGPGPDRGYVFQQDALLPWLTVLDNVALglelqGVPKAEARERAEELLELVGLSGFENAYP---- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 apvGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPS-ALRLAGRV 1213
Cdd:cd03293 130 ---HQLSGGMRQRVALARALA---VDPDVLLLDEPFSALDALTREQLQEELLD-IWRETGKTVLLVTHDIDeAVFLADRV 202
|
....
gi 1624762192 1214 VLLG 1217
Cdd:cd03293 203 VVLS 206
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
953-1222 |
1.35e-14 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 79.30 E-value: 1.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 953 KSIDFYQVCFvypqlHHNIKNGSLMLTLYDFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDENFN---- 1027
Cdd:PTZ00265 381 KKIQFKNVRF-----HYDTRKDVEIYKDLNFTLT--EGKTYAFVGESGCGKSTILKLIERLYDPTEgDIIINDSHNlkdi 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1028 NMIWMNCEelINIFRYCYLELSLPLPN--KEDSANIIRLDGIPIACFSTTFLRKAfGILEQNPCVFENMTFFENISFFAD 1105
Cdd:PTZ00265 454 NLKWWRSK--IGVVSQDPLLFSNSIKNniKYSLYSLKDLEALSNYYNEDGNDSQE-NKNKRNSCRAKCAGDLNDMSNTTD 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1106 NASVREM-----------VITSARVCRCESFIKNHPLSYDAPVG----RLSAGERQRLALARALVSSragSGLFLLDEPT 1170
Cdd:PTZ00265 531 SNELIEMrknyqtikdseVVDVSKKVLIHDFVSALPDKYETLVGsnasKLSGGQKQRISIARAIIRN---PKILILDEAT 607
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1171 AHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPSALRLAGRVVLLGDGGRS 1222
Cdd:PTZ00265 608 SSLDNKSEYLVQKTINN-LKGNENRITIIIAHRLSTIRYANTIFVLSNRERG 658
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
980-1229 |
1.46e-14 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 74.74 E-value: 1.46e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceelinifrycyLELsLPLpnkedSA 1059
Cdd:COG1121 22 LEDVSLTIPPGEFVAIVGPNGAGKSTLLKAI-----------------------------------LGL-LPP-----TS 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACfsttfLRKAFGILEQNP--------CVFE--NMTFFENISFF-----ADNASVREMVitsARVcRCES 1124
Cdd:COG1121 61 GTVRLFGKPPRR-----ARRRIGYVPQRAevdwdfpiTVRDvvLMGRYGRRGLFrrpsrADREAVDEAL---ERV-GLED 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1125 FIknhplsyDAPVGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRP 1204
Cdd:COG1121 132 LA-------DRPIGELSGGQQQRVLLARALAQ---DPDLLLLDEPFAGVDAATEEALYELLREL--RREGKTILVVTHDL 199
|
250 260
....*....|....*....|....*.
gi 1624762192 1205 SALR-LAGRVVLLgdGGRSMYEGPPS 1229
Cdd:COG1121 200 GAVReYFDRVLLL--NRGLVAHGPPE 223
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
962-1220 |
2.57e-14 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 77.45 E-value: 2.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 962 FVYPQLHHNIkngslmltLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDpvrtikIDENfnnMIwmnceelinif 1041
Cdd:PRK10789 321 FTYPQTDHPA--------LENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFD------VSEG---DI----------- 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1042 RYcyleLSLPLPNkedsaniIRLDGipiacfsttfLRKAFGILEQNPCVFENmTFFENISFFADNASvREMVITSARVCR 1121
Cdd:PRK10789 373 RF----HDIPLTK-------LQLDS----------WRSRLAVVSQTPFLFSD-TVANNIALGRPDAT-QQEIEHVARLAS 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1122 CESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARggsTA 1197
Cdd:PRK10789 430 VHDDILRLPQGYDTEVGErgvmLSGGQKQRISIARALLLN---AEILILDDALSAVDGRTEHQILHNLRQWGEGR---TV 503
|
250 260
....*....|....*....|...
gi 1624762192 1198 IIISHRPSALRLAGRVVLLGDGG 1220
Cdd:PRK10789 504 IISAHRLSALTEASEILVMQHGH 526
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
982-1231 |
2.82e-14 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 73.24 E-value: 2.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAkfRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:cd03224 20 SLTV--PEGEIVALLGRNGAGKTTLLKTIMGLLPP-----------------------------------------RSGS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTtFLRKAFGI--LEQNPCVFENMTFFENI---SFFADNASVREMVitsARVC----RCESFIKNhpls 1132
Cdd:cd03224 57 IRFDGRDITGLPP-HERARAGIgyVPEGRRIFPELTVEENLllgAYARRRAKRKARL---ERVYelfpRLKERRKQ---- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 ydaPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAhldGHSEGCVEEALAEFMRARGGSTAIIIS--HRPSALRLA 1210
Cdd:cd03224 129 ---LAGTLSGGEQQMLAIARALMSRPK---LLLLDEPSE---GLAPKIVEEIFEAIRELRDEGVTILLVeqNARFALEIA 199
|
250 260
....*....|....*....|.
gi 1624762192 1211 GRVVLLgDGGRSMYEGPPSGL 1231
Cdd:cd03224 200 DRAYVL-ERGRVVLEGTAAEL 219
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
988-1226 |
5.99e-14 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 72.54 E-value: 5.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANIIrLDGI 1067
Cdd:cd03257 29 KKGETLGLVGESGSGKSTLARAILGLLKP----------------------------------------TSGSII-FDGK 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFL---RKAFGILEQNPcvfenMTFFeNISFfadnaSVREMVitsarvcrCESFIKNHPLSYDAP-------- 1136
Cdd:cd03257 68 DLLKLSRRLRkirRKEIQMVFQDP-----MSSL-NPRM-----TIGEQI--------AEPLRIHGKLSKKEArkeavlll 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 ---VG-----------RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISH 1202
Cdd:cd03257 129 lvgVGlpeevlnryphELSGGQRQRVAIARALALN---PKLLIADEPTSALDVSVQAQILDLLKK-LQEELGLTLLFITH 204
|
250 260
....*....|....*....|....*
gi 1624762192 1203 RPSALR-LAGRVVLLgDGGRSMYEG 1226
Cdd:cd03257 205 DLGVVAkIADRVAVM-YAGKIVEEG 228
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
982-1226 |
7.73e-14 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 75.87 E-value: 7.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANI 1061
Cdd:COG0488 16 DVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEP----------------------------------------DSGEV 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIacfsttflrkafGILEQNPCVFENMTFFENIsfFADNASVREMVITSARVCRCESFIKNHPLSY-------- 1133
Cdd:COG0488 56 SIPKGLRI------------GYLPQEPPLDDDLTVLDTV--LDGDAELRALEAELEELEAKLAEPDEDLERLaelqeefe 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 -------------------------DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDghsegcVE--EALA 1186
Cdd:COG0488 122 alggweaearaeeilsglgfpeedlDRPVSELSGGWRRRVALARALLSE---PDLLLLDEPTNHLD------LEsiEWLE 192
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1624762192 1187 EFMRARGGsTAIIISH-RpsAL--RLAGRVVLLGDGGRSMYEG 1226
Cdd:COG0488 193 EFLKNYPG-TVLVVSHdR--YFldRVATRILELDRGKLTLYPG 232
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
989-1231 |
1.16e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 73.71 E-value: 1.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 989 AGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIdenfnnmiwmnceelinifrycyleLSLPLPNKEDSANIiRLDGI 1067
Cdd:PRK13536 66 SGECFGLLGPNGAGKSTIARMILGMTSPDAgKITV-------------------------LGVPVPARARLARA-RIGVV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PiacfsttflrkAFGILEQNPCVFENMTFFENisFFADNASVREMVITSA-RVCRCESfiknhplSYDAPVGRLSAGERQ 1146
Cdd:PRK13536 120 P-----------QFDNLDLEFTVRENLLVFGR--YFGMSTREIEAVIPSLlEFARLES-------KADARVSDLSGGMKR 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1147 RLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMrARgGSTAIIISH-RPSALRLAGRVVLLgDGGRSMYE 1225
Cdd:PRK13536 180 RLTLARALIND---PQLLILDEPTTGLDPHARHLIWERLRSLL-AR-GKTILLTTHfMEEAERLCDRLCVL-EAGRKIAE 253
|
....*.
gi 1624762192 1226 GPPSGL 1231
Cdd:PRK13536 254 GRPHAL 259
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
977-1231 |
1.93e-13 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 71.32 E-value: 1.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 977 MLTL-------------YDFTAKfrAGEITALIGETGSGKSTimrLLkrmydpvrtikidenfnnmiwmnceELINIFRy 1043
Cdd:COG3840 1 MLRLddltyrygdfplrFDLTIA--AGERVAILGPSGAGKST---LL-------------------------NLIAGFL- 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1044 cylelslplpnKEDSANIIrLDGIPIacfstTFLRKA---FGILEQNPCVFENMTFFENISFFAD-----NASVREMVIT 1115
Cdd:COG3840 50 -----------PPDSGRIL-WNGQDL-----TALPPAerpVSMLFQENNLFPHLTVAQNIGLGLRpglklTAEQRAQVEQ 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1116 SARVCRCESFIKNHPlsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDghsEGCVEE--ALAEFMRARG 1193
Cdd:COG3840 113 ALERVGLAGLLDRLP-------GQLSGGQRQRVALARCLVRKRP---ILLLDEPFSALD---PALRQEmlDLVDELCRER 179
|
250 260 270
....*....|....*....|....*....|....*....
gi 1624762192 1194 GSTAIIISHRPS-ALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:COG3840 180 GLTVLMVTHDPEdAARIADRVLLV-ADGRIAADGPTAAL 217
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
980-1219 |
2.46e-13 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 71.22 E-value: 2.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDpvrtikidenfnnmiwmnceeLINIFRYcylelslplpnkEDSa 1059
Cdd:COG1117 27 LKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMND---------------------LIPGARV------------EGE- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 niIRLDGIPIacFSTTF----LRKAFGILEQNPCVFeNMTFFENISF------FADNASVREMVITSAR-------Vcrc 1122
Cdd:COG1117 73 --ILLDGEDI--YDPDVdvveLRRRVGMVFQKPNPF-PKSIYDNVAYglrlhgIKSKSELDEIVEESLRkaalwdeV--- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1123 esfiKNHpLsyDAPVGRLSAGERQRLALARAL-----VssragsglFLLDEPTAHLDGHSEGCVEEALAEFmraRGGSTA 1197
Cdd:COG1117 145 ----KDR-L--KKSALGLSGGQQQRLCIARALavepeV--------LLMDEPTSALDPISTAKIEELILEL---KKDYTI 206
|
250 260
....*....|....*....|...
gi 1624762192 1198 IIISHRPS-ALRLAGRVVLLGDG 1219
Cdd:COG1117 207 VIVTHNMQqAARVSDYTAFFYLG 229
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
980-1228 |
3.15e-13 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 72.49 E-value: 3.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSA 1059
Cdd:COG1118 18 LDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETP----------------------------------------DSG 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIrLDGipiacfsttflRKAF----------GILEQNPCVFENMTFFENISFFADNASVREMVITsARVCRC------E 1123
Cdd:COG1118 58 RIV-LNG-----------RDLFtnlpprerrvGFVFQHYALFPHMTVAENIAFGLRVRPPSKAEIR-ARVEELlelvqlE 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1124 SFIKNHPlsydapvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGsTAIIISH- 1202
Cdd:COG1118 125 GLADRYP-------SQLSGGQRQRVALARALAVE---PEVLLLDEPFGALDAKVRKELRRWLRRLHDELGG-TTVFVTHd 193
|
250 260
....*....|....*....|....*.
gi 1624762192 1203 RPSALRLAGRVVLLgDGGRSMYEGPP 1228
Cdd:COG1118 194 QEEALELADRVVVM-NQGRIEQVGTP 218
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
1134-1216 |
3.46e-13 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 69.57 E-value: 3.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEGCVEEALAEfmRARGGSTAIIISHRPSALRLAGRV 1213
Cdd:NF040873 114 GRQLGELSGGQRQRALLAQGLAQ---EADLLLLDEPTTGLDAESRERIIALLAE--EHARGATVVVVTHDLELVRRADPC 188
|
...
gi 1624762192 1214 VLL 1216
Cdd:NF040873 189 VLL 191
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
988-1219 |
6.46e-13 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 70.37 E-value: 6.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLDGI 1067
Cdd:cd03294 48 REGEIFVIMGLSGSGKSTLLRCINRLIEP-----------------------------------------TSGKVLIDGQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFL----RKAFGILEQNPCVFENMTFFENISFFADNASV-----REMVITSARVCRCESFIKNHPlsydapvG 1138
Cdd:cd03294 87 DIAAMSRKELrelrRKKISMVFQSFALLPHRTVLENVAFGLEVQGVpraerEERAAEALELVGLEGWEHKYP-------D 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEalaEFMR--ARGGSTAIIISHRPS-ALRLAGRVVL 1215
Cdd:cd03294 160 ELSGGMQQRVGLARALA---VDPDILLMDEAFSALDPLIRREMQD---ELLRlqAELQKTIVFITHDLDeALRLGDRIAI 233
|
....
gi 1624762192 1216 LGDG 1219
Cdd:cd03294 234 MKDG 237
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
980-1221 |
6.97e-13 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 70.12 E-value: 6.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceelinifryCYLElslplpnkEDSA 1059
Cdd:COG1116 27 LDDVSLTVAAGEFVALVGPSGCGKSTLLRLI---------------------------------AGLE--------KPTS 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIacfstTFLRKAFGILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPlsyd 1134
Cdd:COG1116 66 GEVLVDGKPV-----TGPGPDRGVVFQEPALLPWLTVLDNVALglelrGVPKAERRERARELLELVGLAGFEDAYP---- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 apvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDghsegcveEALAEFMR-------ARGGSTAIIISHRPS-A 1206
Cdd:COG1116 137 ---HQLSGGMRQRVAIARALANDPE---VLLMDEPFGALD--------ALTRERLQdellrlwQETGKTVLFVTHDVDeA 202
|
250
....*....|....*.
gi 1624762192 1207 LRLAGRVVLLGDG-GR 1221
Cdd:COG1116 203 VFLADRVVVLSARpGR 218
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
988-1231 |
7.97e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 70.60 E-value: 7.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceelinifrycyleLSLPLPNkedsANIIRLDGI 1067
Cdd:PRK13537 31 QRGECFGLLGPNGAGKTTTLRML-------------------------------------LGLTHPD----AGSISLCGE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACfSTTFLRKAFGILEQnpcvFENM----TFFENISFFA-----DNASVREMVITSARVCRCESfiknhplSYDAPVG 1138
Cdd:PRK13537 70 PVPS-RARHARQRVGVVPQ----FDNLdpdfTVRENLLVFGryfglSAAAARALVPPLLEFAKLEN-------KADAKVG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMrARgGSTAIIISH-RPSALRLAGRVVLLg 1217
Cdd:PRK13537 138 ELSGGMKRRLTLARALVND---PDVLVLDEPTTGLDPQARHLMWERLRSLL-AR-GKTILLTTHfMEEAERLCDRLCVI- 211
|
250
....*....|....
gi 1624762192 1218 DGGRSMYEGPPSGL 1231
Cdd:PRK13537 212 EEGRKIAEGAPHAL 225
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
980-1219 |
9.31e-13 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 69.69 E-value: 9.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRM---YDpvRTIKIDEnfnnmiwmnceelinifRYCYLelslplpnke 1056
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLieiYD--SKIKVDG-----------------KVLYF---------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1057 dSANIIRLDGIPiacfsttfLRKAFGILEQNPCVFENMTFFENISFFADNASVREMVITSARVCRCESFIKNHPLSYD-- 1134
Cdd:PRK14246 77 -GKDIFQIDAIK--------LRKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDrl 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 -APVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmraRGGSTAIIISHRP-SALRLAGR 1212
Cdd:PRK14246 148 nSPASQLSGGQQQRLTIARALALK---PKVLLMDEPTSMIDIVNSQAIEKLITEL---KNEIAIVIVSHNPqQVARVADY 221
|
....*..
gi 1624762192 1213 VVLLGDG 1219
Cdd:PRK14246 222 VAFLYNG 228
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
980-1226 |
2.74e-12 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 67.68 E-value: 2.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMydpvrtIKIDENFNNMIWMNCEEL-INIFRYCylelslplpnkeds 1058
Cdd:cd03234 23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGR------VEGGGTTSGQILFNGQPRkPDQFQKC-------------- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1059 aniirldgipiacfsttflrkaFGILEQNPCVFENMTFFENISFFADNA-------SVREMVITSARVCRCESFIKNHPL 1131
Cdd:cd03234 83 ----------------------VAYVRQDDILLPGLTVRETLTYTAILRlprkssdAIRKKRVEDVLLRDLALTRIGGNL 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1132 sydapVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISH--RPSALRL 1209
Cdd:cd03234 141 -----VKGISGGERRRVSIAVQLLWD---PKVLILDEPTSGLDSFTALNLVSTLSQL--ARRNRIVILTIHqpRSDLFRL 210
|
250
....*....|....*..
gi 1624762192 1210 AGRVVLLgDGGRSMYEG 1226
Cdd:cd03234 211 FDRILLL-SSGEIVYSG 226
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
988-1227 |
4.24e-12 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 67.26 E-value: 4.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANIiRLDGI 1067
Cdd:cd03300 24 KEGEFFTLLGPSGCGKTTLLRLIAGFETP----------------------------------------TSGEI-LLDGK 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTflRKAFGILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPlsydapvGRLSA 1142
Cdd:cd03300 63 DITNLPPH--KRPVNTVFQNYALFPHLTVFENIAFglrlkKLPKAEIKERVAEALDLVQLEGYANRKP-------SQLSG 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1143 GERQRLALARALVSSragSGLFLLDEPTAHLDGHSEgcvEEALAEFMR--ARGGSTAIIISHRPS-ALRLAGRVVLLGDG 1219
Cdd:cd03300 134 GQQQRVAIARALVNE---PKVLLLDEPLGALDLKLR---KDMQLELKRlqKELGITFVFVTHDQEeALTMSDRIAVMNKG 207
|
250
....*....|....*
gi 1624762192 1220 -------GRSMYEGP 1227
Cdd:cd03300 208 kiqqigtPEEIYEEP 222
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
987-1219 |
7.27e-12 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 66.75 E-value: 7.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 987 FRAGEITALIGETGSGKSTIMRLLKRMydpvrtikidenfnnmiwmnceelinifrycylelslplpNKEDSANIiRLDG 1066
Cdd:COG1124 28 VAPGESFGLVGESGSGKSTLLRALAGL----------------------------------------ERPWSGEV-TFDG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 IPIACFSTTFLRKAFGILEQ------NPCvfenMTFFENIS-------FFADNASVREMVitsARVCRCESFIKNHPlsy 1133
Cdd:COG1124 67 RPVTRRRRKAFRRRVQMVFQdpyaslHPR----HTVDRILAeplrihgLPDREERIAELL---EQVGLPPSFLDRYP--- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 dapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPSAL-RLAGR 1212
Cdd:COG1124 137 ----HQLSGGQRQRVAIARALILEPE---LLLLDEPTSALDVSVQAEILNLLKD-LREERGLTYLFVSHDLAVVaHLCDR 208
|
....*..
gi 1624762192 1213 VVLLGDG 1219
Cdd:COG1124 209 VAVMQNG 215
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
980-1219 |
8.26e-12 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 66.01 E-value: 8.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRllkrmydpvrtikidenfnnmiwmnCeelINifrycYLElslplpnKEDSA 1059
Cdd:cd03262 16 LKGIDLTVKKGEVVVIIGPSGSGKSTLLR-------------------------C---IN-----LLE-------EPDSG 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIrLDGIPIACFSTTF--LRKAFGILEQNPCVFENMTFFENISF---FADNASVREMVITS----ARVcRCESFIKNHP 1130
Cdd:cd03262 56 TII-IDGLKLTDDKKNIneLRQKVGMVFQQFNLFPHLTVLENITLapiKVKGMSKAEAEERAlellEKV-GLADKADAYP 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 lsydapvGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDghSEgCVEEALaEFMR--ARGGSTAIIISHRPS-AL 1207
Cdd:cd03262 134 -------AQLSGGQQQRVAIARALA---MNPKVMLFDEPTSALD--PE-LVGEVL-DVMKdlAEEGMTMVVVTHEMGfAR 199
|
250
....*....|..
gi 1624762192 1208 RLAGRVVLLGDG 1219
Cdd:cd03262 200 EVADRVIFMDDG 211
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
980-1227 |
9.86e-12 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 65.51 E-value: 9.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDenfnnmiwmnceelinifrycylelslplpnkeds 1058
Cdd:cd03369 24 LKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEgKIEID----------------------------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1059 aniirldGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFadNASVREMVITSARVCRCESfiknhplsydapvg 1138
Cdd:cd03369 69 -------GIDISTIPLEDLRSSLTIIPQDPTLFSG-TIRSNLDPF--DEYSDEEIYGALRVSEGGL-------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRargGSTAIIISHRPSALRLAGRVVLLGD 1218
Cdd:cd03369 125 NLSQGQRQLLCLARALLKRPR---VLVLDEATASIDYATDALIQKTIREEFT---NSTILTIAHRLRTIIDYDKILVMDA 198
|
....*....
gi 1624762192 1219 GGRSMYEGP 1227
Cdd:cd03369 199 GEVKEYDHP 207
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
955-1229 |
1.26e-11 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 66.69 E-value: 1.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPqlhhniknGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDenfnNMIWMN 1033
Cdd:TIGR04520 1 IEVENVSFSYP--------ESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSgKVTVD----GLDTLD 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 CEELINIfrycylelslplpnkedsaniirldgipiacfsttflRKAFGILEQNPcvfEN----MTFFENISFFADNASV 1109
Cdd:TIGR04520 69 EENLWEI-------------------------------------RKKVGMVFQNP---DNqfvgATVEDDVAFGLENLGV 108
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1110 -----REMVITSARVCRCESFIKNHPLsydapvgRLSAGERQRLALARAL-VSSRagsgLFLLDEPTAHLD--GHSEgcV 1181
Cdd:TIGR04520 109 preemRKRVDEALKLVGMEDFRDREPH-------LLSGGQKQRVAIAGVLaMRPD----IIILDEATSMLDpkGRKE--V 175
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1624762192 1182 EEALAEfMRARGGSTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPPS 1229
Cdd:TIGR04520 176 LETIRK-LNKEEGITVISITHDMEEAVLADRVIVM-NKGKIVAEGTPR 221
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
955-1229 |
2.23e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 65.81 E-value: 2.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQlhhnikNGSLMLTLYDFTAKfrAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnc 1034
Cdd:PRK13635 6 IRVEHISFRYPD------AATYALKDVSFSVY--EGEWVAIVGHNGSGKSTLAKLLNGLLLP------------------ 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNP-CVFENMTFFENISFFADNASV--RE 1111
Cdd:PRK13635 60 -----------------------EAGTITVGGMVLSEETVWDVRRQVGMVFQNPdNQFVGATVQDDVAFGLENIGVprEE 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1112 MV--ITSA-RVCRCESFIKNHPlsydapvGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLD--GHSEgcVEEALA 1186
Cdd:PRK13635 117 MVerVDQAlRQVGMEDFLNREP-------HRLSGGQKQRVAIAGVLA---LQPDIIILDEATSMLDprGRRE--VLETVR 184
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1624762192 1187 EfMRARGGSTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPPS 1229
Cdd:PRK13635 185 Q-LKEQKGITVLSITHDLDEAAQADRVIVM-NKGEILEEGTPE 225
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
976-1219 |
2.87e-11 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 66.98 E-value: 2.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 976 LMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVRtikidenfnnmiwmnceelinifrycylelslplpnk 1055
Cdd:PRK10070 40 LSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTR------------------------------------- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1056 edsaNIIRLDGIPIACFSTTFLR----KAFGILEQNPCVFENMTFFENISFFADNASV-----REMVITSARVCRCESFI 1126
Cdd:PRK10070 83 ----GQVLIDGVDIAKISDAELRevrrKKIAMVFQSFALMPHMTVLDNTAFGMELAGInaeerREKALDALRQVGLENYA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1127 KNHPlsydapvGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHR-PS 1205
Cdd:PRK10070 159 HSYP-------DELSGGMRQRVGLARALA---INPDILLMDEAFSALDPLIRTEMQDELVK-LQAKHQRTIVFISHDlDE 227
|
250
....*....|....
gi 1624762192 1206 ALRLAGRVVLLGDG 1219
Cdd:PRK10070 228 AMRIGDRIAIMQNG 241
|
|
| F420-0_ABC_ATP |
TIGR03873 |
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ... |
982-1229 |
2.99e-11 |
|
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Pssm-ID: 163585 [Multi-domain] Cd Length: 256 Bit Score: 65.22 E-value: 2.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVRTiKIDENFNNMIWMNCEElinifRYCYLEL-------SLPLPN 1054
Cdd:TIGR03873 19 GVDVTAPPGSLTGLLGPNGSGKSTLLRLLAGALRPDAG-TVDLAGVDLHGLSRRA-----RARRVALveqdsdtAVPLTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1055 KEdsanIIRLDGIPiacfsttfLRKAFGIleqnpcvfenmtffeniSFFADNASVREMVitsARVcRCESFIknhplsyD 1134
Cdd:TIGR03873 93 RD----VVALGRIP--------HRSLWAG-----------------DSPHDAAVVDRAL---ART-ELSHLA-------D 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1135 APVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPS-ALRLAGRV 1213
Cdd:TIGR03873 133 RDMSTLSGGERQRVHVARALAQE---PKLLLLDEPTNHLDVRAQLETLALVREL--AATGVTVVAALHDLNlAASYCDHV 207
|
250
....*....|....*.
gi 1624762192 1214 VLLgDGGRSMYEGPPS 1229
Cdd:TIGR03873 208 VVL-DGGRVVAAGPPR 222
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
980-1231 |
3.61e-11 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 64.73 E-value: 3.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRllkrmydpvrtikidenfnnmiwmnCeelINIfrycyLElslplpnKEDSA 1059
Cdd:PRK09493 17 LHNIDLNIDQGEVVVIIGPSGSGKSTLLR-------------------------C---INK-----LE-------EITSG 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIrLDGIPIACFSTT--FLRKAFGILEQNPCVFENMTFFENISFfaDNASVREMVITSARVCRCESFIK-------NHp 1130
Cdd:PRK09493 57 DLI-VDGLKVNDPKVDerLIRQEAGMVFQQFYLFPHLTALENVMF--GPLRVRGASKEEAEKQARELLAKvglaeraHH- 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 lsYDApvgRLSAGERQRLALARAL-VSSRagsgLFLLDEPTAHLDG---HSEGCVEEALAEfmrarGGSTAIIISHRPS- 1205
Cdd:PRK09493 133 --YPS---ELSGGQQQRVAIARALaVKPK----LMLFDEPTSALDPelrHEVLKVMQDLAE-----EGMTMVIVTHEIGf 198
|
250 260
....*....|....*....|....*.
gi 1624762192 1206 ALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:PRK09493 199 AEKVASRLIFI-DKGRIAEDGDPQVL 223
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
1134-1228 |
4.30e-11 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 65.89 E-value: 4.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSS-RagsgLFLLDEPTAHLDGHSEgcvEEALAEFMRARgGSTAI---IISHRPS-ALR 1208
Cdd:COG4148 128 DRRPATLSGGERQRVAIGRALLSSpR----LLLMDEPLAALDLARK---AEILPYLERLR-DELDIpilYVSHSLDeVAR 199
|
90 100
....*....|....*....|
gi 1624762192 1209 LAGRVVLLgDGGRSMYEGPP 1228
Cdd:COG4148 200 LADHVVLL-EQGRVVASGPL 218
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
989-1204 |
5.99e-11 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 63.28 E-value: 5.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 989 AGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLDGIP 1068
Cdd:cd03231 25 AGEALQVTGPNGSGKTTLLRILAGLSPP-----------------------------------------LAGRVLLNGGP 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1069 IAcFSTTFLRKAFGILEQNPCVFENMTFFENISFFADNASvREMVITS-ARVcrcesfikNHPLSYDAPVGRLSAGERQR 1147
Cdd:cd03231 64 LD-FQRDSIARGLLYLGHAPGIKTTLSVLENLRFWHADHS-DEQVEEAlARV--------GLNGFEDRPVAQLSAGQQRR 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1624762192 1148 LALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMrARGGStAIIISHRP 1204
Cdd:cd03231 134 VALARLLLSGRP---LWILDEPTTALDKAGVARFAEAMAGHC-ARGGM-VVLTTHQD 185
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
980-1219 |
7.59e-11 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 66.29 E-value: 7.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:PRK10535 24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKP-----------------------------------------TS 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTTFL----RKAFGILEQNPCVFENMTFFENISFFADNASVRemviTSARVCRCESFIKNHPLS--Y 1133
Cdd:PRK10535 63 GTYRVAGQDVATLDADALaqlrREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLE----RKQRLLRAQELLQRLGLEdrV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEgcvEEALAEFMRARG-GSTAIIISHRPSALRLAGR 1212
Cdd:PRK10535 139 EYQPSQLSGGQQQRVSIARALMN---GGQVILADEPTGALDSHSG---EEVMAILHQLRDrGHTVIIVTHDPQVAAQAER 212
|
....*..
gi 1624762192 1213 VVLLGDG 1219
Cdd:PRK10535 213 VIEIRDG 219
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
952-1229 |
8.74e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 64.24 E-value: 8.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 952 SKSIDFYQVCFVYPQLHHN-IKNGSLmlTLYDftakfraGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmi 1030
Cdd:PRK13632 5 SVMIKVENVSFSYPNSENNaLKNVSF--EINE-------GEYVAILGHNGSGKSTISKILTGLLKP-------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1031 wmnceelinifrycylelslplpnkedSANIIRLDGIPIACFSTTFLRKAFGILEQNP-CVFENMTFFENISFFADNASV 1109
Cdd:PRK13632 62 ---------------------------QSGEIKIDGITISKENLKEIRKKIGIIFQNPdNQFIGATVEDDIAFGLENKKV 114
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1110 --REM---VITSARVCRCESFIKNHPLSydapvgrLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD--GHSEgcve 1182
Cdd:PRK13632 115 ppKKMkdiIDDLAKKVGMEDYLDKEPQN-------LSGGQKQRVAIASVLALNPE---IIIFDESTSMLDpkGKRE---- 180
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1183 eaLAEFM---RARGGSTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPPS 1229
Cdd:PRK13632 181 --IKKIMvdlRKTRKKTLISITHDMDEAILADKVIVF-SEGKLIAQGKPK 227
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
977-1236 |
1.13e-10 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 63.06 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 977 MLTL------YD-----FTAKFRAGEITALIGETGSGKSTIMrllkrmydpvrtikidenfnnmiwmnceELINIFrycy 1045
Cdd:PRK10771 1 MLKLtditwlYHhlpmrFDLTVERGERVAILGPSGAGKSTLL----------------------------NLIAGF---- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1046 lelslpLPNKEDSaniIRLDGIPiaCFSTTFLRKAFGILEQNPCVFENMTFFENISFFAD-----NASVREMVITSARVC 1120
Cdd:PRK10771 49 ------LTPASGS---LTLNGQD--HTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNpglklNAAQREKLHAIARQM 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1121 RCESFIKNHPlsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGH---------SEGCVEEALaefmra 1191
Cdd:PRK10771 118 GIEDLLARLP-------GQLSGGQRQRVALARCLVREQP---ILLLDEPFSALDPAlrqemltlvSQVCQERQL------ 181
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1624762192 1192 rggsTAIIISHR-PSALRLAGRVVLLGDgGRSMYEGPPSGLGKGAV 1236
Cdd:PRK10771 182 ----TLLMVSHSlEDAARIAPRSLVVAD-GRIAWDGPTDELLSGKA 222
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
979-1219 |
1.18e-10 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 62.49 E-value: 1.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 979 TLYDFTAKFRAGEITALIGETGSGKST-IMRLLKRMYdpvrtikidenfnnmiwmnceelinifrycylelslplpnked 1057
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSlLSALLGELE------------------------------------------- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 saniiRLDGipiacfsTTFLRKAFGILEQNPCVFeNMTFFENISFFADNASVR-EMVItsaRVCRCESFIKNHPLSYDAP 1136
Cdd:cd03250 57 -----KLSG-------SVSVPGSIAYVSQEPWIQ-NGTIRENILFGKPFDEERyEKVI---KACALEPDLEILPDGDLTE 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 VGR----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGH-SEGCVEEALAEFMraRGGSTAIIISHRPSALRLAG 1211
Cdd:cd03250 121 IGEkginLSGGQKQRISLARAVYSD---ADIYLLDDPLSAVDAHvGRHIFENCILGLL--LNNKTRILVTHQLQLLPHAD 195
|
....*...
gi 1624762192 1212 RVVLLGDG 1219
Cdd:cd03250 196 QIVVLDNG 203
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
931-1227 |
1.26e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 66.15 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 931 IKKIGNF--------EFDDIGRIIGGFSLSKSIDFYQVCFVY-PQLHHnikngslmlTLYDFTAKFRAGEITALIGETGS 1001
Cdd:PLN03232 1203 VERVGNYidlpseatAIIENNRPVSGWPSRGSIKFEDVHLRYrPGLPP---------VLHGLSFFVSPSEKVGVVGRTGA 1273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1002 GKSTIMRLLkrmydpvrtikidenfnnmiwmnceeliniFRYCYLElslplpnkedsANIIRLDGIPIACFSTTFLRKAF 1081
Cdd:PLN03232 1274 GKSSMLNAL------------------------------FRIVELE-----------KGRIMIDDCDVAKFGLTDLRRVL 1312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1082 GILEQNPCVFENMTFFeNISFFAD--NASVREmVITSARVcrcESFIKNHPLSYDAPVGR----LSAGERQRLALARALV 1155
Cdd:PLN03232 1313 SIIPQSPVLFSGTVRF-NIDPFSEhnDADLWE-ALERAHI---KDVIDRNPFGLDAEVSEggenFSVGQRQLLSLARALL 1387
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1156 SSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRArggSTAIIISHRPSALRLAGRVVLLGDGGRSMYEGP 1227
Cdd:PLN03232 1388 RR---SKILVLDEATASVDVRTDSLIQRTIREEFKS---CTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSP 1453
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
982-1231 |
2.67e-10 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 61.92 E-value: 2.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAkfRAGEITALIGETGSGKST----IMRLLkrmydPVR--TIKIDEnfnnmiwmncEELINifrycylelsLPlPNK 1055
Cdd:COG0410 23 SLEV--EEGEIVALLGRNGAGKTTllkaISGLL-----PPRsgSIRFDG----------EDITG----------LP-PHR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1056 edsanIIRLdGIpiacfsttflrkafGILEQNPCVFENMTFFENI---SFFADNASVREMVItsARVC----RCESFIKN 1128
Cdd:COG0410 75 -----IARL-GI--------------GYVPEGRRIFPSLTVEENLllgAYARRDRAEVRADL--ERVYelfpRLKERRRQ 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1129 hplsydaPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHL------DghsegcVEEALAEfMRARGgsTAIIIS- 1201
Cdd:COG0410 133 -------RAGTLSGGEQQMLAIGRALMSRPK---LLLLDEPSLGLapliveE------IFEIIRR-LNREG--VTILLVe 193
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1202 -HRPSALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:COG0410 194 qNARFALEIADRAYVL-ERGRIVLEGTAAEL 223
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
955-1219 |
2.69e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 62.90 E-value: 2.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPQlhhnikngSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKrmydpvrtikidenfnnmiwmnc 1034
Cdd:PRK13640 6 VEFKHVSFTYPD--------SKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLIN----------------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelSLPLPNkEDSANIIRLDGIPIACFSTTFLRKAFGILEQNP-CVFENMTFFENISFFADNASV--RE 1111
Cdd:PRK13640 55 --------------GLLLPD-DNPNSKITVDGITLTAKTVWDIREKVGIVFQNPdNQFVGATVGDDVAFGLENRAVprPE 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1112 MVITSARVCR---CESFIKNHPlsydapvGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEF 1188
Cdd:PRK13640 120 MIKIVRDVLAdvgMLDYIDSEP-------ANLSGGQKQRVAIAGILA---VEPKIIILDESTSMLDPAGKEQILKLIRKL 189
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1189 MRARgGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK13640 190 KKKN-NLTVISITHDIDEANMADQVLVLDDG 219
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
988-1231 |
2.94e-10 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 62.07 E-value: 2.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmnceelINIfrycylELSLPLPNKEdsaNIIRLdg 1066
Cdd:PRK11264 27 KPGEVVAIIGPSGSGKTTLLRCINLLEQPEAgTIRVGD-------------ITI------DTARSLSQQK---GLIRQ-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 ipiacfsttfLRKAFGILEQNPCVFENMTFFENIsffADNASVREMVITSARVCRCESFIKNHPLS--YDAPVGRLSAGE 1144
Cdd:PRK11264 83 ----------LRQHVGFVFQNFNLFPHRTVLENI---IEGPVIVKGEPKEEATARARELLAKVGLAgkETSYPRRLSGGQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1145 RQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVE---EALAEFMRarggsTAIIISHRPSALR-LAGRVVLLgDGG 1220
Cdd:PRK11264 150 QQRVAIARALAMRPE---VILFDEPTSALDPELVGEVLntiRQLAQEKR-----TMVIVTHEMSFARdVADRAIFM-DQG 220
|
250
....*....|.
gi 1624762192 1221 RSMYEGPPSGL 1231
Cdd:PRK11264 221 RIVEQGPAKAL 231
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1141-1219 |
3.16e-10 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 61.68 E-value: 3.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1141 SAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmRARGgsTAII-ISHRPSAL-RLAGRVVLLGD 1218
Cdd:COG4778 154 SGGEQQRVNIARGFIADPP---LLLLDEPTASLDAANRAVVVELIEEA-KARG--TAIIgIFHDEEVReAVADRVVDVTP 227
|
.
gi 1624762192 1219 G 1219
Cdd:COG4778 228 F 228
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
1136-1214 |
3.27e-10 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 61.08 E-value: 3.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1136 PVGRLSAGERQ------RLALARALVSSragSGLFLLDEPTAHLDghsEGCVEEALAEFMRARGGST---AIIISHRPSA 1206
Cdd:cd03240 112 MRGRCSGGEKVlasliiRLALAETFGSN---CGILALDEPTTNLD---EENIEESLAEIIEERKSQKnfqLIVITHDEEL 185
|
....*...
gi 1624762192 1207 LRLAGRVV 1214
Cdd:cd03240 186 VDAADHIY 193
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
978-1229 |
3.57e-10 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 63.32 E-value: 3.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 978 LTLYDftakfraGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnked 1057
Cdd:PRK11607 40 LTIYK-------GEIFALLGASGCGKSTLLRMLAGFEQP----------------------------------------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 SANIIRLDGIPIAcfSTTFLRKAFGILEQNPCVFENMTFFENISFFAD---------NASVREMVitsaRVCRCESFIKN 1128
Cdd:PRK11607 72 TAGQIMLDGVDLS--HVPPYQRPINMMFQSYALFPHMTVEQNIAFGLKqdklpkaeiASRVNEML----GLVHMQEFAKR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1129 HPlsydapvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRaRGGSTAIIISH-RPSAL 1207
Cdd:PRK11607 146 KP-------HQLSGGQRQRVALARSLAKR---PKLLLLDEPMGALDKKLRDRMQLEVVDILE-RVGVTCVMVTHdQEEAM 214
|
250 260
....*....|....*....|....*....
gi 1624762192 1208 RLAGRVVLLGDGG-------RSMYEGPPS 1229
Cdd:PRK11607 215 TMAGRIAIMNRGKfvqigepEEIYEHPTT 243
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1134-1219 |
4.01e-10 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 61.64 E-value: 4.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSegcvEEALAEFMR--ARGGSTAII-ISHRPSALrLA 1210
Cdd:COG1119 137 DRPFGTLSQGEQRRVLIARALVKDPE---LLILDEPTAGLDLGA----RELLLALLDklAAEGAPTLVlVTHHVEEI-PP 208
|
90
....*....|.
gi 1624762192 1211 G--RVVLLGDG 1219
Cdd:COG1119 209 GitHVLLLKDG 219
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
980-1229 |
4.17e-10 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 63.67 E-value: 4.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRM--YDPVRTIKIdenFNNMIwmnCEELINIFRYCYLelSLPLPNKED 1057
Cdd:TIGR03269 16 LKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRII---YHVAL---CEKCGYVERPSKV--GEPCPVCGG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 SANIIRLDGIPIACFSTTFLRKAFGILEQ-------NPCVFEN-MTFFENISFFADNASVR-----EMVITSARVCRces 1124
Cdd:TIGR03269 88 TLEPEEVDFWNLSDKLRRRIRKRIAIMLQrtfalygDDTVLDNvLEALEEIGYEGKEAVGRavdliEMVQLSHRITH--- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1125 fiknhplsydapVGR-LSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRARgGSTAIIISHR 1203
Cdd:TIGR03269 165 ------------IARdLSGGEKQRVVLARQLAKEPF---LFLADEPTGTLDPQTAKLVHNALEEAVKAS-GISMVLTSHW 228
|
250 260
....*....|....*....|....*..
gi 1624762192 1204 PSAL-RLAGRVVLLGDGGRSMyEGPPS 1229
Cdd:TIGR03269 229 PEVIeDLSDKAIWLENGEIKE-EGTPD 254
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
987-1231 |
5.77e-10 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 61.65 E-value: 5.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 987 FRAGEITALIGETGSGKSTIMRLLKRMYDPVRTikidenfnnmiwmnceeliniFRYcylelslplpnkedSANIIrLDG 1066
Cdd:PRK14271 44 FPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSG---------------------YRY--------------SGDVL-LGG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 IPIACFSTTF-LRKAFGILEQNPCVFEnMTFFENISffadnASVR--EMV-------ITSARVCRCESFIKNHPLSYDAP 1136
Cdd:PRK14271 88 RSIFNYRDVLeFRRRVGMLFQRPNPFP-MSIMDNVL-----AGVRahKLVprkefrgVAQARLTEVGLWDAVKDRLSDSP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 VgRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSegcvEEALAEFMRARGGS-TAIIISHR-PSALRLAGRVV 1214
Cdd:PRK14271 162 F-RLSGGQQQLLCLARTLA---VNPEVLLLDEPTSALDPTT----TEKIEEFIRSLADRlTVIIVTHNlAQAARISDRAA 233
|
250
....*....|....*..
gi 1624762192 1215 LLGDgGRSMYEGPPSGL 1231
Cdd:PRK14271 234 LFFD-GRLVEEGPTEQL 249
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1134-1204 |
6.17e-10 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 60.20 E-value: 6.17e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEP-TAhLDGHSEGCVEEALAEfmRARGGSTAIIISHRP 1204
Cdd:PRK13538 124 DVPVRQLSAGQQRRVALARLWLTRAP---LWILDEPfTA-IDKQGVARLEALLAQ--HAEQGGMVILTTHQD 189
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
982-1231 |
6.94e-10 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 60.60 E-value: 6.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANI 1061
Cdd:cd03263 20 DLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRP----------------------------------------TSGTA 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IrLDGIPIAcfstTFLRKAF---GILEQNPCVFENMTFFENISFFA-----DNASVREMVITSARVCRCESFIknhplsy 1133
Cdd:cd03263 60 Y-INGYSIR----TDRKAARqslGYCPQFDALFDELTVREHLRFYArlkglPKSEIKEEVELLLRVLGLTDKA------- 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEfmrARGGSTAIIISHRPS-ALRLAGR 1212
Cdd:cd03263 128 NKRARTLSGGMKRKLSLAIALI---GGPSVLLLDEPTSGLDPASRRAIWDLILE---VRKGRSIILTTHSMDeAEALCDR 201
|
250
....*....|....*....
gi 1624762192 1213 VVLLGDgGRSMYEGPPSGL 1231
Cdd:cd03263 202 IAIMSD-GKLRCIGSPQEL 219
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
980-1237 |
8.54e-10 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 60.96 E-value: 8.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:PRK10575 27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPP-----------------------------------------SE 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACF-STTFLRKAFGILEQNPCVfENMTFFENIS---FFADNASVREMVITSARVCRCESFIKNHPLSYDA 1135
Cdd:PRK10575 66 GEILLDAQPLESWsSKAFARKVAYLPQQLPAA-EGMTVRELVAigrYPWHGALGRFGAADREKVEEAISLVGLKPLAHRL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1136 pVGRLSAGERQRLALArALVSSraGSGLFLLDEPTAHLD-GHSegcVEE-ALAEFMRARGGSTAIIISHRPS-ALRLAGR 1212
Cdd:PRK10575 145 -VDSLSGGERQRAWIA-MLVAQ--DSRCLLLDEPTSALDiAHQ---VDVlALVHRLSQERGLTVIAVLHDINmAARYCDY 217
|
250 260
....*....|....*....|....*
gi 1624762192 1213 VVLLgDGGRSMYEGPPSGLGKGAVL 1237
Cdd:PRK10575 218 LVAL-RGGEMIAQGTPAELMRGETL 241
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1136-1202 |
9.70e-10 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 62.83 E-value: 9.70e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1624762192 1136 PVGRLSAGERQRLALARALvssRAGSGLFLLDEPTAHLDGHSEGCVEEALAEFmrarGGStAIIISH 1202
Cdd:PRK11819 442 KVGVLSGGERNRLHLAKTL---KQGGNVLLLDEPTNDLDVETLRALEEALLEF----PGC-AVVISH 500
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
982-1228 |
1.20e-09 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 61.78 E-value: 1.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAkfRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:PRK09536 23 DLSV--REGSLVGLVGPNGAGKTTLLRAINGTLTP-----------------------------------------TAGT 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTFLRKAFGILEQNPCV-FE-------NMTFFENISFF-----ADNASVRE-MVITSArvcrcESFIk 1127
Cdd:PRK09536 60 VLVAGDDVEALSARAASRRVASVPQDTSLsFEfdvrqvvEMGRTPHRSRFdtwteTDRAAVERaMERTGV-----AQFA- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1128 nhplsyDAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRpsaL 1207
Cdd:PRK09536 134 ------DRPVTSLSGGERQRVLLARALAQA---TPVLLLDEPTASLDINHQVRTLELVRRL--VDDGKTAVAAIHD---L 199
|
250 260
....*....|....*....|....*
gi 1624762192 1208 RLAGR----VVLLGDgGRSMYEGPP 1228
Cdd:PRK09536 200 DLAARycdeLVLLAD-GRVRAAGPP 223
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
970-1226 |
1.30e-09 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 59.18 E-value: 1.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 970 NIKNGSLMLtLYDFTAKFRAGEITALIGETGSGKSTIMRLLKrmydpvrtikidenfnnmiwmnceelinifrycylels 1049
Cdd:cd03232 14 PVKGGKRQL-LNNISGYVKPGTLTALMGESGAGKTTLLDVLA-------------------------------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1050 lplpNKEDSANI---IRLDGIPIacfSTTFLRKAfGILEQNPCVFENMTffenisffadnasVREmvitsarvcrcesfi 1126
Cdd:cd03232 55 ----GRKTAGVItgeILINGRPL---DKNFQRST-GYVEQQDVHSPNLT-------------VRE--------------- 98
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1127 knhPLSYDAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSegcvEEALAEFMR--ARGGSTAIIISHRP 1204
Cdd:cd03232 99 ---ALRFSALLRGLSVEQRKRLTIGVELA---AKPSILFLDEPTSGLDSQA----AYNIVRFLKklADSGQAILCTIHQP 168
|
250 260
....*....|....*....|....
gi 1624762192 1205 SALRLA--GRVVLLGDGGRSMYEG 1226
Cdd:cd03232 169 SASIFEkfDRLLLLKRGGKTVYFG 192
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
948-1231 |
1.39e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 62.83 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 948 GFSLSKSIDFYQVCFVY-----PQLHHnikngslmltlydFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVRtiki 1022
Cdd:PLN03130 1231 GWPSSGSIKFEDVVLRYrpelpPVLHG-------------LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELER---- 1293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1023 denfnnmiwmnceelinifrycylelslplpnkedsaNIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENMTFFeNISF 1102
Cdd:PLN03130 1294 -------------------------------------GRILIDGCDISKFGLMDLRKVLGIIPQAPVLFSGTVRF-NLDP 1335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1103 FAD--NASVREmvitSARVCRCESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGH 1176
Cdd:PLN03130 1336 FNEhnDADLWE----SLERAHLKDVIRRNSLGLDAEVSEagenFSVGQRQLLSLARALLRR---SKILVLDEATAAVDVR 1408
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1624762192 1177 SEGCVEEALAEFMRArggSTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPPSGL 1231
Cdd:PLN03130 1409 TDALIQKTIREEFKS---CTMLIIAHRLNTIIDCDRILVL-DAGRVVEFDTPENL 1459
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
982-1204 |
1.53e-09 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 58.91 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnnmiwmnceELINIFRYCYLELSLPLPNkedsan 1060
Cdd:TIGR01189 20 SFT--LNAGEALQVTGPNGIGKTTLLRILAGLLRPDSgEVRWNG-----------TPLAEQRDEPHENILYLGH------ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1061 iirLDGipiacfsttflrkafgiLEQNPCVFENMTFFENISFFADNA---SVREMVITSARvcrcesfiknhplsyDAPV 1137
Cdd:TIGR01189 81 ---LPG-----------------LKPELSALENLHFWAAIHGGAQRTiedALAAVGLTGFE---------------DLPA 125
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1624762192 1138 GRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMrARGGStAIIISHRP 1204
Cdd:TIGR01189 126 AQLSAGQQRRLALARLWLSRRP---LWILDEPTTALDKAGVALLAGLLRAHL-ARGGI-VLLTTHQD 187
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1134-1202 |
1.79e-09 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 61.87 E-value: 1.79e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmrargGSTAIIISH 1202
Cdd:TIGR03719 156 DADVTKLSGGERRRVALCRLLLSK---PDMLLLDEPTNHLDAESVAWLERHLQEY-----PGTVVAVTH 216
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1137-1202 |
2.45e-09 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 61.49 E-value: 2.45e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1624762192 1137 VGRLSAGERQRLALARALvssRAGSGLFLLDEPTAHLDGHSEGCVEEALAEFmrargGSTAIIISH 1202
Cdd:TIGR03719 441 VGQLSGGERNRVHLAKTL---KSGGNVLLLDEPTNDLDVETLRALEEALLNF-----AGCAVVISH 498
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1139-1221 |
3.69e-09 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 60.98 E-value: 3.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSegcvEEALAEFMRARGGSTAII-ISHRPSALRLAGRVVLLG 1217
Cdd:COG4178 485 VLSLGEQQRLAFARLLL---HKPDWLFLDEATSALDEEN----EAALYQLLREELPGTTVIsVGHRSTLAAFHDRVLELT 557
|
....
gi 1624762192 1218 DGGR 1221
Cdd:COG4178 558 GDGS 561
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
980-1174 |
5.30e-09 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 57.59 E-value: 5.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGeITALIGETGSGKSTIMRLLKrmydpvrTIKidenfnnmiwmnceelinifrycylelslplpnkEDSA 1059
Cdd:cd03264 16 LDGVSLTLGPG-MYGLLGPNGAGKTTLMRILA-------TLT----------------------------------PPSS 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTTfLRKAFGILEQNPCVFENMTFFENISFFA-----DNASVRemvitsARVCRCESFIKNHPlSYD 1134
Cdd:cd03264 54 GTIRIDGQDVLKQPQK-LRRRIGYLPQEFGVYPNFTVREFLDYIAwlkgiPSKEVK------ARVDEVLELVNLGD-RAK 125
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1624762192 1135 APVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD 1174
Cdd:cd03264 126 KKIGSLSGGMRRRVGIAQALVGDPS---ILIVDEPTAGLD 162
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
971-1219 |
5.81e-09 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 58.41 E-value: 5.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 971 IKNGSLMLTLYDFTAKFRAGEITALIGETGSGKSTimrLLKRMydpvrtikidenfnnmiwmnceelinifrycylelSL 1050
Cdd:PRK03695 3 LNDVAVSTRLGPLSAEVRAGEILHLVGPNGAGKST---LLARM-----------------------------------AG 44
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1051 PLPNKEDsaniIRLDGIPIACFSTTFL--RKAFGILEQNPcVFeNMTFFENISFF-ADNASVREMVITSARVCrcESFIK 1127
Cdd:PRK03695 45 LLPGSGS----IQFAGQPLEAWSAAELarHRAYLSQQQTP-PF-AMPVFQYLTLHqPDKTRTEAVASALNEVA--EALGL 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1128 NHPLSydAPVGRLSAGERQRLALARALV----SSRAGSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHR 1203
Cdd:PRK03695 117 DDKLG--RSVNQLSGGEWQRVRLAAVVLqvwpDINPAGQLLLLDEPMNSLDVAQQAALDRLLSEL--CQQGIAVVMSSHD 192
|
250
....*....|....*..
gi 1624762192 1204 PS-ALRLAGRVVLLGDG 1219
Cdd:PRK03695 193 LNhTLRHADRVWLLKQG 209
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
974-1219 |
6.08e-09 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 57.73 E-value: 6.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 974 GSLMLTLYDFTAKFRAGEITALIGETGSGKSTimrLLKRMYDPVRTIKidenfNNMIWMNCEElinifrycylelSLPLP 1053
Cdd:cd03290 11 GSGLATLSNINIRIPTGQLTMIVGQVGCGKSS---LLLAILGEMQTLE-----GKVHWSNKNE------------SEPSF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1054 NKEDSANiirldgipiacfsttflRKAFGILEQNPCVFeNMTFFENISFFADNASVREMVITSArvCRCESFIKNHPLSY 1133
Cdd:cd03290 71 EATRSRN-----------------RYSVAYAAQKPWLL-NATVEENITFGSPFNKQRYKAVTDA--CSLQPDIDLLPFGD 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGR----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGH-SEGCVEEALAEFMRaRGGSTAIIISHRPSALR 1208
Cdd:cd03290 131 QTEIGErginLSGGQRQRICVARALYQN---TNIVFLDDPFSALDIHlSDHLMQEGILKFLQ-DDKRTLVLVTHKLQYLP 206
|
250
....*....|.
gi 1624762192 1209 LAGRVVLLGDG 1219
Cdd:cd03290 207 HADWIIAMKDG 217
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
988-1227 |
6.52e-09 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 57.98 E-value: 6.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnNMiwmnceelinifrycyleLSLPlpnkedSANIIRLDGI 1067
Cdd:cd03258 29 PKGEIFGIIGRSGAGKSTLIRCI-----------------NG------------------LERP------TSGSVLVDGT 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFLRKA---FGILEQNPCVFENMTFFENISFFADNASVREMVITsARVCRC------ESFIKNHPlsydapvG 1138
Cdd:cd03258 68 DLTLLSGKELRKArrrIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIE-ERVLELlelvglEDKADAYP-------A 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRARgGSTAIIISHRPSALR-LAGRVVLLg 1217
Cdd:cd03258 140 QLSGGQKQRVGIARALANNPK---VLLCDEATSALDPETTQSILALLRDINREL-GLTIVLITHEMEVVKrICDRVAVM- 214
|
250
....*....|
gi 1624762192 1218 DGGRSMYEGP 1227
Cdd:cd03258 215 EKGEVVEEGT 224
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
1062-1233 |
7.69e-09 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 58.00 E-value: 7.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTFLRKAFGILEQNPCVFENmtffeNISFFAD--NASVREMVITSARVCRCESFIKNHPLSYDAPVGR 1139
Cdd:cd03288 78 IVIDGIDISKLPLHTLRSRLSIILQDPILFSG-----SIRFNLDpeCKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 ----LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALaefMRARGGSTAIIISHRPSALRLAGRVVL 1215
Cdd:cd03288 153 ggenFSVGQRQLFCLARAFVRK---SSILIMDEATASIDMATENILQKVV---MTAFADRTVVTIAHRVSTILDADLVLV 226
|
170
....*....|....*...
gi 1624762192 1216 LGDGGRSMYEGPPSGLGK 1233
Cdd:cd03288 227 LSRGILVECDTPENLLAQ 244
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
992-1227 |
7.98e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 57.93 E-value: 7.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 992 ITALIGETGSGKSTIMRLLKRMYDPVRTIKIdenfnnmiwmncEELINIFrycylelslplpnkedSANIIRLDGIPIAc 1071
Cdd:PRK14267 32 VFALMGPSGCGKSTLLRTFNRLLELNEEARV------------EGEVRLF----------------GRNIYSPDVDPIE- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1072 fsttfLRKAFGILEQNPCVFENMTFFENIS-------FFADNASVREMVITSARVCRCESFIKNHPLSYDapvGRLSAGE 1144
Cdd:PRK14267 83 -----VRREVGMVFQYPNPFPHLTIYDNVAigvklngLVKSKKELDERVEWALKKAALWDEVKDRLNDYP---SNLSGGQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1145 RQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmraRGGSTAIIISHRPS-ALRLAGRVVLLGDG---- 1219
Cdd:PRK14267 155 RQRLVIARALAMK---PKILLMDEPTANIDPVGTAKIEELLFEL---KKEYTIVLVTHSPAqAARVSDYVAFLYLGklie 228
|
250
....*....|.
gi 1624762192 1220 ---GRSMYEGP 1227
Cdd:PRK14267 229 vgpTRKVFENP 239
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1124-1202 |
9.96e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 59.44 E-value: 9.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1124 SFIKN---HPLS----YDAPVGRLSAGERQRLALARALvsSRAGSgLFLLDEPTAHLDghsegcVEE------ALAEFMR 1190
Cdd:PRK13409 431 SYYKSeiiKPLQlerlLDKNVKDLSGGELQRVAIAACL--SRDAD-LYLLDEPSAHLD------VEQrlavakAIRRIAE 501
|
90
....*....|..
gi 1624762192 1191 ARgGSTAIIISH 1202
Cdd:PRK13409 502 ER-EATALVVDH 512
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
987-1219 |
1.05e-08 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 57.19 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 987 FRAGEITALIGETGSGKSTIMRLLkrmydpvrtIKIDENFNNMIWMNCEElinIFRycylelslpLPNKEdsaniirldg 1066
Cdd:PRK10908 25 MRPGEMAFLTGHSGAGKSTLLKLI---------CGIERPSAGKIWFSGHD---ITR---------LKNRE---------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 IPiacfsttFLRKAFGILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPLsydapvgRLS 1141
Cdd:PRK10908 74 VP-------FLRRQIGMIFQDHHLLMDRTVYDNVAIpliiaGASGDDIRRRVSAALDKVGLLDKAKNFPI-------QLS 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1142 AGERQRLALARALVSSRAgsgLFLLDEPTAHLDGH-SEGcVEEALAEFMRArgGSTAIIISHRPSAL-RLAGRVVLLGDG 1219
Cdd:PRK10908 140 GGEQQRVGIARAVVNKPA---VLLADEPTGNLDDAlSEG-ILRLFEEFNRV--GVTVLMATHDIGLIsRRSYRMLTLSDG 213
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
990-1228 |
1.16e-08 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 57.69 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMRLLKRMYDPVrtikidenfNNMIWmnceelinifrycylelslplpnkedsaniirLDGIPI 1069
Cdd:PRK10253 33 GHFTAIIGPNGCGKSTLLRTLSRLMTPA---------HGHVW--------------------------------LDGEHI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1070 ACFSTTFLRKAFGILEQNPCVFENMTFFENIS--------FFADNASVREMVITSARVCRCESFIKNHPlsydapVGRLS 1141
Cdd:PRK10253 72 QHYASKEVARRIGLLAQNATTPGDITVQELVArgryphqpLFTRWRKEDEEAVTKAMQATGITHLADQS------VDTLS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1142 AGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGSTAIIISHRPSALRLAGRVVLLGDgGR 1221
Cdd:PRK10253 146 GGQRQRAWIAMVLAQETA---IMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALRE-GK 221
|
....*..
gi 1624762192 1222 SMYEGPP 1228
Cdd:PRK10253 222 IVAQGAP 228
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1129-1202 |
1.24e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 59.03 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1129 HPLsYDAPVGRLSAGERQRLALARALvSSRAgsGLFLLDEPTAHLDghsegcVEE------ALAEFMRARgGSTAIIISH 1202
Cdd:COG1245 446 EKL-LDKNVKDLSGGELQRVAIAACL-SRDA--DLYLLDEPSAHLD------VEQrlavakAIRRFAENR-GKTAMVVDH 514
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
978-1213 |
1.41e-08 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 57.48 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 978 LTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDpvrtikidenfnnmiwmnceeLINIFRycyLELSLPLPNKed 1057
Cdd:PRK14243 24 LAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLND---------------------LIPGFR---VEGKVTFHGK-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 saNIIRLDGIPIAcfsttfLRKAFGILEQNPCVFENmTFFENISFFAD----NASVREMVITSARVC----RCESFIKNH 1129
Cdd:PRK14243 78 --NLYAPDVDPVE------VRRRIGMVFQKPNPFPK-SIYDNIAYGARingyKGDMDELVERSLRQAalwdEVKDKLKQS 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1130 PLSydapvgrLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRArggSTAIIISHRpsaLRL 1209
Cdd:PRK14243 149 GLS-------LSGGQQQRLCIARAIAVQ---PEVILMDEPCSALDPISTLRIEELMHELKEQ---YTIIIVTHN---MQQ 212
|
....
gi 1624762192 1210 AGRV 1213
Cdd:PRK14243 213 AARV 216
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
1140-1202 |
1.49e-08 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 54.76 E-value: 1.49e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1624762192 1140 LSAGERQRLALARALVSSragSGLFLLDEPTAHLDghSEGCveEALAEFMRARGGsTAIIISH 1202
Cdd:cd03221 71 LSGGEKMRLALAKLLLEN---PNLLLLDEPTNHLD--LESI--EALEEALKEYPG-TVILVSH 125
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
990-1229 |
1.73e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 57.36 E-value: 1.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMrllkrmydpvrtikidENFNNMIwmnceelinifrycylelslplpnKEDSANIIrLDGIPI 1069
Cdd:PRK13637 33 GEFVGLIGHTGSGKSTLI----------------QHLNGLL------------------------KPTSGKII-IDGVDI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1070 A--CFSTTFLRKAFGILEQNP--CVFENmTFFENISFFADNASVREMVItSARVCRCESFIKnhpLSYDAPVGR----LS 1141
Cdd:PRK13637 72 TdkKVKLSDIRKKVGLVFQYPeyQLFEE-TIEKDIAFGPINLGLSEEEI-ENRVKRAMNIVG---LDYEDYKDKspfeLS 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1142 AGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEgcvEEALAEF--MRARGGSTAIIISHRPSAL-RLAGRVVLLgD 1218
Cdd:PRK13637 147 GGQKRRVAIAGVVAME---PKILILDEPTAGLDPKGR---DEILNKIkeLHKEYNMTIILVSHSMEDVaKLADRIIVM-N 219
|
250
....*....|.
gi 1624762192 1219 GGRSMYEGPPS 1229
Cdd:PRK13637 220 KGKCELQGTPR 230
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
1140-1221 |
2.81e-08 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 54.47 E-value: 2.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALVssrAGSGLFLLDEPTAHLDghsegcvEEALAEFMRA-RGGSTAII-ISHRPSALRLAGRVVLLG 1217
Cdd:cd03223 92 LSGGEQQRLAFARLLL---HKPKFVFLDEATSALD-------EESEDRLYQLlKELGITVIsVGHRPSLWKFHDRVLDLD 161
|
....
gi 1624762192 1218 DGGR 1221
Cdd:cd03223 162 GEGG 165
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1140-1213 |
2.98e-08 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 55.98 E-value: 2.98e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624762192 1140 LSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRpsaLRLAGRV 1213
Cdd:PRK11629 146 LSGGERQRVAIARALVNNPR---LVLADEPTGNLDARNADSIFQLLGE-LNRLQGTAFLVVTHD---LQLAKRM 212
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1131-1226 |
3.54e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 57.65 E-value: 3.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 LSYDAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDghsegcVE--EALAEFMRARGGSTaIIISHRPSALR 1208
Cdd:PRK11147 148 LDPDAALSSLSGGWLRKAALGRALVSN---PDVLLLDEPTNHLD------IEtiEWLEGFLKTFQGSI-IFISHDRSFIR 217
|
90
....*....|....*....
gi 1624762192 1209 -LAGRVVLLGDGGRSMYEG 1226
Cdd:PRK11147 218 nMATRIVDLDRGKLVSYPG 236
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1082-1228 |
5.39e-08 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 56.58 E-value: 5.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1082 GILEQNPCVFENMTFFENISF-----FADNASVREMVITSARVCRCESFIKNHPLSydapvgrLSAGERQRLALARALVS 1156
Cdd:PRK11000 78 GMVFQSYALYPHLSVAENMSFglklaGAKKEEINQRVNQVAEVLQLAHLLDRKPKA-------LSGGQRQRVAIGRTLVA 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1157 SragSGLFLLDEPTAHLDGhsegcveeALAEFMRA-------RGGSTAIIISH-RPSALRLAGRVVLLgDGGRSMYEGPP 1228
Cdd:PRK11000 151 E---PSVFLLDEPLSNLDA--------ALRVQMRIeisrlhkRLGRTMIYVTHdQVEAMTLADKIVVL-DAGRVAQVGKP 218
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
969-1203 |
6.22e-08 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 57.48 E-value: 6.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 969 HNIKNGSLM-------------LTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDpvrtikidenfnnmiwmnce 1035
Cdd:PTZ00243 1302 HPVQAGSLVfegvqmryreglpLVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVE-------------------- 1361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1036 elinifrYCYLElslplpnkedsaniIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFF--ADNASV---R 1110
Cdd:PTZ00243 1362 -------VCGGE--------------IRVNGREIGAYGLRELRRQFSMIPQDPVLFDG-TVRQNVDPFleASSAEVwaaL 1419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1111 EMVITSARVCR----CESFIKNHPLSYdapvgrlSAGERQRLALARALVssRAGSGLFLLDEPTAHLDghsegcveEAL- 1185
Cdd:PTZ00243 1420 ELVGLRERVASesegIDSRVLEGGSNY-------SVGQRQLMCMARALL--KKGSGFILMDEATANID--------PALd 1482
|
250 260
....*....|....*....|..
gi 1624762192 1186 ----AEFMRARGGSTAIIISHR 1203
Cdd:PTZ00243 1483 rqiqATVMSAFSAYTVITIAHR 1504
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
986-1203 |
6.29e-08 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 56.86 E-value: 6.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 986 KFRAGEITALIGETGSGKSTIMRLLKRMYdPVRTikidenFNNMIWMNCEELInifrycylelslplpnkedsANIIRld 1065
Cdd:PRK13549 27 KVRAGEIVSLCGENGAGKSTLMKVLSGVY-PHGT------YEGEIIFEGEELQ--------------------ASNIR-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1066 gipiacfSTTflRKAFGILEQNPCVFENMTFFENIsfFADNASVREMVITSARV-CRCESFIK--NHPLSYDAPVGRLSA 1142
Cdd:PRK13549 78 -------DTE--RAGIAIIHQELALVKELSVLENI--FLGNEITPGGIMDYDAMyLRAQKLLAqlKLDINPATPVGNLGL 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1624762192 1143 GERQRLALARALvSSRAgsGLFLLDEPTAHLDgHSEGCVEEALAEFMRARgGSTAIIISHR 1203
Cdd:PRK13549 147 GQQQLVEIAKAL-NKQA--RLLILDEPTASLT-ESETAVLLDIIRDLKAH-GIACIYISHK 202
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
980-1231 |
6.60e-08 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 55.22 E-value: 6.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRmydpvrtikidenfnnmiwmnceelinifrycylelSLPLPNKEDSA 1059
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG------------------------------------DLTGGGAPRGA 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NI---IRLDGIPIACFSTTFLRKAFGILEQ--NPCvfenmtffenisfFAdnASVREMVI--------TSARVCRCESFI 1126
Cdd:PRK13547 61 RVtgdVTLNGEPLAAIDAPRLARLRAVLPQaaQPA-------------FA--FSAREIVLlgrypharRAGALTHRDGEI 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1127 KNHPLSY---DAPVGR----LSAGERQRLALARALV------SSRAGSGLFLLDEPTAHLD-GHSEGCVEEALAEFMRAR 1192
Cdd:PRK13547 126 AWQALALagaTALVGRdvttLSGGELARVQFARVLAqlwpphDAAQPPRYLLLDEPTAALDlAHQHRLLDTVRRLARDWN 205
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1624762192 1193 GGSTAIIisHRPS-ALRLAGRVVLLGDgGRSMYEGPPSGL 1231
Cdd:PRK13547 206 LGVLAIV--HDPNlAARHADRIAMLAD-GAIVAHGAPADV 242
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
980-1229 |
6.64e-08 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 55.02 E-value: 6.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVrtikidenfnnmiwmnceelinifrycylelslplpnkedsA 1059
Cdd:PRK11231 18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQ-----------------------------------------S 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENMTFFENISF-------------FADNASV-REMVITsarvcRCESF 1125
Cdd:PRK11231 57 GTVFLGDKPISMLSSRQLARRLALLPQHHLTPEGITVRELVAYgrspwlslwgrlsAEDNARVnQAMEQT-----RINHL 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1126 IknhplsyDAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD-GHSegcVEeaLAEFMRARG--GSTAIIISH 1202
Cdd:PRK11231 132 A-------DRRLTDLSGGQRQRAFLAMVLAQDTP---VVLLDEPTTYLDiNHQ---VE--LMRLMRELNtqGKTVVTVLH 196
|
250 260
....*....|....*....|....*...
gi 1624762192 1203 R-PSALRLAGRVVLLgDGGRSMYEGPPS 1229
Cdd:PRK11231 197 DlNQASRYCDHLVVL-ANGHVMAQGTPE 223
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
966-1229 |
6.67e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 55.62 E-value: 6.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 966 QLHHNIKNGSLMLTlyDFTAKFRAGEITALIGETGSGKSTIMrllkrmydpvrtikidENFNNMIwmnceelinifrycy 1045
Cdd:PRK13636 10 ELNYNYSDGTHALK--GININIKKGEVTAILGGNGAGKSTLF----------------QNLNGIL--------------- 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1046 lelslplpnKEDSANIIRlDGIPIACFSTTF--LRKAFGILEQNPcvfENMTF----FENISFFADNASVREMVITSarv 1119
Cdd:PRK13636 57 ---------KPSSGRILF-DGKPIDYSRKGLmkLRESVGMVFQDP---DNQLFsasvYQDVSFGAVNLKLPEDEVRK--- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1120 cRCESFIKNHPLSY--DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLD--GHSEgcVEEALAEfMRARGGS 1195
Cdd:PRK13636 121 -RVDNALKRTGIEHlkDKPTHCLSFGQKKRVAIAGVLVME---PKVLVLDEPTAGLDpmGVSE--IMKLLVE-MQKELGL 193
|
250 260 270
....*....|....*....|....*....|....
gi 1624762192 1196 TAIIISHRPSALRLAGRVVLLGDGGRSMYEGPPS 1229
Cdd:PRK13636 194 TIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPK 227
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1134-1202 |
6.87e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 56.67 E-value: 6.87e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmraRGgsTAIIISH 1202
Cdd:PRK11819 158 DAKVTKLSGGERRRVALCRLLLEK---PDMLLLDEPTNHLDAESVAWLEQFLHDY---PG--TVVAVTH 218
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
980-1229 |
8.62e-08 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 56.59 E-value: 8.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKrmydpvrtikidenfnnmiwmnceeliniFRycylelslpLPNKEDSA 1059
Cdd:TIGR00955 41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALA-----------------------------FR---------SPKGVKGS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIacfSTTFLRKAFGILEQNPCVFENMTFFENISFfadNASVR--EMVITSARVCRCESFIKNHPLSYDA-- 1135
Cdd:TIGR00955 83 GSVLLNGMPI---DAKEMRAISAYVQQDDLFIPTLTVREHLMF---QAHLRmpRRVTKKEKRERVDEVLQALGLRKCAnt 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1136 ------PVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPSA--L 1207
Cdd:TIGR00955 157 rigvpgRVKGLSGGERKRLAFASELLTDPP---LLFCDEPTSGLDSFMAYSVVQVLKGL--AQKGKTIICTIHQPSSelF 231
|
250 260
....*....|....*....|..
gi 1624762192 1208 RLAGRVVLLgDGGRSMYEGPPS 1229
Cdd:TIGR00955 232 ELFDKIILM-AEGRVAYLGSPD 252
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
1093-1219 |
1.04e-07 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 56.71 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1093 NMTFFENISFF--ADNASVREMVitsaRVCRCESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSRagsGLFLL 1166
Cdd:PTZ00243 734 NATVRGNILFFdeEDAARLADAV----RVSQLEADLAQLGGGLETEIGEkgvnLSGGQKARVSLARAVYANR---DVYLL 806
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1624762192 1167 DEPTAHLDGH-SEGCVEEAlaeFMRARGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PTZ00243 807 DDPLSALDAHvGERVVEEC---FLGALAGKTRVLATHQVHVVPRADYVVALGDG 857
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
976-1231 |
1.09e-07 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 56.49 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 976 LMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRmydpvrtikidenfnnmiwmnceelINifrycylelslplpnk 1055
Cdd:TIGR00957 1298 LDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFR-------------------------IN---------------- 1336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1056 EDSANIIRLDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASvrEMVITSARVCRCESFIKNHP--LSY 1133
Cdd:TIGR00957 1337 ESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPVLFSG-SLRMNLDPFSQYSD--EEVWWALELAHLKTFVSALPdkLDH 1413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVG--RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEAL-AEFmrarGGSTAIIISHRPSALRLA 1210
Cdd:TIGR00957 1414 ECAEGgeNLSVGQRQLVCLARALLRK---TKILVLDEATAAVDLETDNLIQSTIrTQF----EDCTVLTIAHRLNTIMDY 1486
|
250 260
....*....|....*....|.
gi 1624762192 1211 GRVVLLgDGGRSMYEGPPSGL 1231
Cdd:TIGR00957 1487 TRVIVL-DKGEVAEFGAPSNL 1506
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
1140-1219 |
2.08e-07 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 53.53 E-value: 2.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEgcVE-EALAEFMRARGGSTAIIISHRPS-ALRLAGRVVLLG 1217
Cdd:PRK11247 134 LSGGQKQRVALARALIHR---PGLLLLDEPLGALDALTR--IEmQDLIESLWQQHGFTVLLVTHDVSeAVAMADRVLLIE 208
|
..
gi 1624762192 1218 DG 1219
Cdd:PRK11247 209 EG 210
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
1093-1228 |
2.78e-07 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 53.39 E-value: 2.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1093 NMTFFENISFFADNASVREMVITSARVcrcesfiknhPLSYdAPVGR----LSAGERQRLALARALVSSRAGSGLFLLDE 1168
Cdd:cd03271 130 DMTVEEALEFFENIPKIARKLQTLCDV----------GLGY-IKLGQpattLSGGEAQRIKLAKELSKRSTGKTLYILDE 198
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1624762192 1169 PTAHLdgHSEGcVEEALAEFMR-ARGGSTAIIISHRPSALRLAGRVVLLG-----DGGRSMYEGPP 1228
Cdd:cd03271 199 PTTGL--HFHD-VKKLLEVLQRlVDKGNTVVVIEHNLDVIKCADWIIDLGpeggdGGGQVVASGTP 261
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
982-1220 |
2.84e-07 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 54.67 E-value: 2.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANI 1061
Cdd:PRK15439 31 DFT--LHAGEVHALLGGNGAGKSTLMKIIAGIVPP-----------------------------------------DSGT 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIACFSTTfLRKAFGI--LEQNPCVFENMTFFENISFfadnasvrEMVITSARVCRCESFIK--NHPLSYDAPV 1137
Cdd:PRK15439 68 LEIGGNPCARLTPA-KAHQLGIylVPQEPLLFPNLSVKENILF--------GLPKRQASMQKMKQLLAalGCQLDLDSSA 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1138 GRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSegcvEEALAEFMRA--RGGSTAIIISHRPSALR-LAGRVV 1214
Cdd:PRK15439 139 GSLEVADRQIVEILRGLMRD---SRILILDEPTASLTPAE----TERLFSRIREllAQGVGIVFISHKLPEIRqLADRIS 211
|
....*.
gi 1624762192 1215 LLGDGG 1220
Cdd:PRK15439 212 VMRDGT 217
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
988-1219 |
2.91e-07 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 52.67 E-value: 2.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLDGI 1067
Cdd:cd03269 24 EKGEIFGLLGPNGAGKTTTIRMILGIILP-----------------------------------------DSGEVLFDGK 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIacfsTTFLRKAFGILEQNPCVFENMTFFENISFFAdnaSVREMVITSARVcRCESFIKNHPLS--YDAPVGRLSAGER 1145
Cdd:cd03269 63 PL----DIAARNRIGYLPEERGLYPKMKVIDQLVYLA---QLKGLKKEEARR-RIDEWLERLELSeyANKRVEELSKGNQ 134
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1624762192 1146 QRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHR-PSALRLAGRVVLLGDG 1219
Cdd:cd03269 135 QKVQFIAAVIHDPE---LLILDEPFSGLDPVNVELLKDVIREL--ARAGKTVILSTHQmELVEELCDRVLLLNKG 204
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
1134-1226 |
3.36e-07 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 52.72 E-value: 3.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARgGSTAIIISHRPSAL-RLAGR 1212
Cdd:cd03267 148 DTPVRQLSLGQRMRAEIAAALLHE---PEILFLDEPTIGLDVVAQENIRNFLKEYNRER-GTTVLLTSHYMKDIeALARR 223
|
90
....*....|....
gi 1624762192 1213 VVLLgDGGRSMYEG 1226
Cdd:cd03267 224 VLVI-DKGRLLYDG 236
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
1057-1228 |
3.64e-07 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 54.63 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1057 DSANIIRLDGIPIACFSTTFLRKAFgileqnpcvfenmTFFENISFFADNASVREMVITS--ARVcrceSFIKNHPLSY- 1133
Cdd:TIGR00630 418 PEALAVTVGGKSIADVSELSIREAH-------------EFFNQLTLTPEEKKIAEEVLKEirERL----GFLIDVGLDYl 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 --DAPVGRLSAGERQRLALAralvsSRAGSGL----FLLDEPTAHLdgHSEGcVEEALAEFMRARG-GSTAIIISHRPSA 1206
Cdd:TIGR00630 481 slSRAAGTLSGGEAQRIRLA-----TQIGSGLtgvlYVLDEPSIGL--HQRD-NRRLINTLKRLRDlGNTLIVVEHDEDT 552
|
170 180
....*....|....*....|....*..
gi 1624762192 1207 LRLAGRVVLLG-----DGGRSMYEGPP 1228
Cdd:TIGR00630 553 IRAADYVIDIGpgageHGGEVVASGTP 579
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
980-1219 |
3.65e-07 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 54.41 E-value: 3.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKID-ENFNNMIWMNCEEL-INIFrycYLELSLPlpnke 1056
Cdd:PRK09700 21 LKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKgTITINnINYNKLDHKLAAQLgIGII---YQELSVI----- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1057 DSANIirLDGIPIACFSTtflRKAFGIleqnpcvfenmtffeNISFFADNASVREMVITSARVCRcesfiknhplSYDAP 1136
Cdd:PRK09700 93 DELTV--LENLYIGRHLT---KKVCGV---------------NIIDWREMRVRAAMMLLRVGLKV----------DLDEK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 VGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDgHSEgcVEEALAEFMRARGGSTAII-ISHRPSALRLAG-RVV 1214
Cdd:PRK09700 143 VANLSISHKQMLEIAKTLMLD---AKVIIMDEPTSSLT-NKE--VDYLFLIMNQLRKEGTAIVyISHKLAEIRRICdRYT 216
|
....*
gi 1624762192 1215 LLGDG 1219
Cdd:PRK09700 217 VMKDG 221
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
968-1221 |
3.95e-07 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 53.15 E-value: 3.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 968 HHNIKNGSLMLT-LYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnceelinifrycyl 1046
Cdd:PRK10419 15 HGGLSGKHQHQTvLNNVSLSLKSGETVALLGRSGCGKSTLARLL------------------------------------ 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1047 eLSLPLPNKedsaNIIRLDGIPIACFSTTfLRKAFGILEQnpcvfenMTFFENISFFADNASVREMV------ITS---- 1116
Cdd:PRK10419 59 -VGLESPSQ----GNVSWRGEPLAKLNRA-QRKAFRRDIQ-------MVFQDSISAVNPRKTVREIIreplrhLLSldka 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1117 ARVCRCESFIKNHPLS---YDAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARG 1193
Cdd:PRK10419 126 ERLARASEMLRAVDLDdsvLDKRPPQLSGGQLQRVCLARALA---VEPKLLILDEAVSNLDLVLQAGVIRLLKK-LQQQF 201
|
250 260 270
....*....|....*....|....*....|..
gi 1624762192 1194 GSTAIIISHRpsaLRL----AGRVVLLgDGGR 1221
Cdd:PRK10419 202 GTACLFITHD---LRLverfCQRVMVM-DNGQ 229
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
988-1231 |
4.42e-07 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 52.66 E-value: 4.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPVRtikidenfnNMIWMNCEElINIFRYCYLELslplpnKEDSANIIRLdgi 1067
Cdd:PRK10619 29 NAGDVISIIGSSGSGKSTFLRCINFLEKPSE---------GSIVVNGQT-INLVRDKDGQL------KVADKNQLRL--- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 piacfsttfLRKAFGILEQNPCVFENMTFFENISffadNASVREMVITSARVcrcesfiKNHPLSYDAPVG--------- 1138
Cdd:PRK10619 90 ---------LRTRLTMVFQHFNLWSHMTVLENVM----EAPIQVLGLSKQEA-------RERAVKYLAKVGideraqgky 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 --RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDghsegcvEEALAEFMR-----ARGGSTAIIISHRPSALRLAG 1211
Cdd:PRK10619 150 pvHLSGGQQQRVSIARALAME---PEVLLFDEPTSALD-------PELVGEVLRimqqlAEEGKTMVVVTHEMGFARHVS 219
|
250 260
....*....|....*....|
gi 1624762192 1212 RVVLLGDGGRSMYEGPPSGL 1231
Cdd:PRK10619 220 SHVIFLHQGKIEEEGAPEQL 239
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
980-1174 |
4.46e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 52.82 E-value: 4.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSA 1059
Cdd:PRK13649 23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVP-----------------------------------------TQ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTT----FLRKAFGILEQNP--CVFENmTFFENISFFADNASV-REMVITSAR-----VCRCESFIK 1127
Cdd:PRK13649 62 GSVRVDDTLITSTSKNkdikQIRKKVGLVFQFPesQLFEE-TVLKDVAFGPQNFGVsQEEAEALAReklalVGISESLFE 140
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1624762192 1128 NHPLSydapvgrLSAGERQRLALARALVSSragSGLFLLDEPTAHLD 1174
Cdd:PRK13649 141 KNPFE-------LSGGQMRRVAIAGILAME---PKILVLDEPTAGLD 177
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
986-1204 |
4.51e-07 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 52.27 E-value: 4.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 986 KFRAGEITALIGETGSGKSTIMRLLKRMYdpvrTIKIDENFNNMIWMNCEElinifrycylELSLplpnkedsaniirLD 1065
Cdd:COG2401 52 EIEPGEIVLIVGASGSGKSTLLRLLAGAL----KGTPVAGCVDVPDNQFGR----------EASL-------------ID 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1066 GIPIAcfsTTFLrKAFGILeqnpcvfenmtffeNISFFADNASVRemvitsarvcrcesfiknhplsydAPVGRLSAGER 1145
Cdd:COG2401 105 AIGRK---GDFK-DAVELL--------------NAVGLSDAVLWL------------------------RRFKELSTGQK 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1624762192 1146 QRLALARALvSSRAgsGLFLLDEPTAHLDGHSEGCVEEALAEFMRaRGGSTAIIISHRP 1204
Cdd:COG2401 143 FRFRLALLL-AERP--KLLVIDEFCSHLDRQTAKRVARNLQKLAR-RAGITLVVATHHY 197
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
973-1201 |
4.56e-07 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 51.66 E-value: 4.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 973 NGSLMLTLYDFtaKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslpl 1052
Cdd:TIGR01166 3 GGPEVLKGLNF--AAERGEVLALLGANGAGKSTLLLHLNGLLRP------------------------------------ 44
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1053 pnkedSANIIRLDGIPIACF--STTFLRKAFGILEQNPcvfENMTF----FENISFFADNASVREMVITsARVCrcESFI 1126
Cdd:TIGR01166 45 -----QSGAVLIDGEPLDYSrkGLLERRQRVGLVFQDP---DDQLFaadvDQDVAFGPLNLGLSEAEVE-RRVR--EALT 113
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1624762192 1127 KNHPLSY-DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGhsEGcVEEALAEFMRARGGSTAIIIS 1201
Cdd:TIGR01166 114 AVGASGLrERPTHCLSGGEKKRVAIAGAVAMR---PDVLLLDEPTAGLDP--AG-REQMLAILRRLRAEGMTVVIS 183
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
955-1228 |
5.02e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 52.68 E-value: 5.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYPqlhhnikNGSLMLTLYDFTakFRAGEITALIGETGSGKSTIMRLLKRMYDPVRTIKIDENFnnmiwmnc 1034
Cdd:PRK13644 2 IRLENVSYSYP-------DGTPALENINLV--IKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGI-------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1035 eelinifrycylelslplpnkeDSANIIRLDGIpiacfsttflRKAFGILEQNP-CVFENMTFFENISFFADNASVREMV 1113
Cdd:PRK13644 65 ----------------------DTGDFSKLQGI----------RKLVGIVFQNPeTQFVGRTVEEDLAFGPENLCLPPIE 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1114 ITSaRVCRCESFIKNHPLSYDAPvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRArg 1193
Cdd:PRK13644 113 IRK-RVDRALAEIGLEKYRHRSP-KTLSGGQGQCVALAGILTME---PECLIFDEVTSMLDPDSGIAVLERIKKLHEK-- 185
|
250 260 270
....*....|....*....|....*....|....*
gi 1624762192 1194 GSTAIIISHRPSALRLAGRVVLLgDGGRSMYEGPP 1228
Cdd:PRK13644 186 GKTIVYITHNLEELHDADRIIVM-DRGKIVLEGEP 219
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
980-1219 |
5.61e-07 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 53.16 E-value: 5.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRmydpvrtikidenfnnmiwmnceelinifrycyLElslplpnkEDSA 1059
Cdd:PRK10851 18 LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAG---------------------------------LE--------HQTS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTTflRKAFGILEQNPCVFENMTFFENISFFADNASVRE---MVITSARVCRCESFIKNHPLSYDAP 1136
Cdd:PRK10851 57 GHIRFHGTDVSRLHAR--DRKVGFVFQHYALFRHMTVFDNIAFGLTVLPRRErpnAAAIKAKVTQLLEMVQLAHLADRYP 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 vGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHsegcVEEALAEFMRARGGS---TAIIISH-RPSALRLAGR 1212
Cdd:PRK10851 135 -AQLSGGQKQRVALARALAVE---PQILLLDEPFGALDAQ----VRKELRRWLRQLHEElkfTSVFVTHdQEEAMEVADR 206
|
....*..
gi 1624762192 1213 VVLLGDG 1219
Cdd:PRK10851 207 VVVMSQG 213
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
980-1227 |
5.72e-07 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 53.41 E-value: 5.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSA 1059
Cdd:PRK09452 30 ISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETP----------------------------------------DSG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIrLDGIPIACFS-------TTFlrkafgileQNPCVFENMTFFENISFF-----ADNASVREMVITSARVCRCESFIK 1127
Cdd:PRK09452 70 RIM-LDGQDITHVPaenrhvnTVF---------QSYALFPHMTVFENVAFGlrmqkTPAAEITPRVMEALRMVQLEEFAQ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1128 NHPLsydapvgRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRaRGGSTAIIISH-RPSA 1206
Cdd:PRK09452 140 RKPH-------QLSGGQQQRVAIARAVVNK---PKVLLLDESLSALDYKLRKQMQNELKALQR-KLGITFVFVTHdQEEA 208
|
250 260
....*....|....*....|....*...
gi 1624762192 1207 LRLAGRVVLLGDGG-------RSMYEGP 1227
Cdd:PRK09452 209 LTMSDRIVVMRDGRieqdgtpREIYEEP 236
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
980-1219 |
5.80e-07 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 52.19 E-value: 5.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnnmiwmnCEElinifrycylelslplpnKEDSA 1059
Cdd:PRK11614 21 LHEVSLHINQGEIVTLIGANGAGKTTLLGTL-----------------------CGD------------------PRATS 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLDGIPIACFSTT-FLRKAFGILEQNPCVFENMTFFENIS---FFADNASVREmvitsarvcRCESFIKNHPLSYDA 1135
Cdd:PRK11614 60 GRIVFDGKDITDWQTAkIMREAVAIVPEGRRVFSRMTVEENLAmggFFAERDQFQE---------RIKWVYELFPRLHER 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1136 PV---GRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPSALRLAGR 1212
Cdd:PRK11614 131 RIqraGTMSGGEQQMLAIGRALMSQ---PRLLLLDEPSLGLAPIIIQQIFDTIEQ-LREQGMTIFLVEQNANQALKLADR 206
|
....*..
gi 1624762192 1213 VVLLGDG 1219
Cdd:PRK11614 207 GYVLENG 213
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
986-1203 |
7.08e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 53.29 E-value: 7.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 986 KFRAGEITALIGETGSGKSTIMRLLKRMYdpvrtikidenfnnmiwmnceelinifrycylelslplPNKEDSANIIrLD 1065
Cdd:TIGR02633 23 EVRPGECVGLCGENGAGKSTLMKILSGVY--------------------------------------PHGTWDGEIY-WS 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1066 GIPIACFSTTFL-RKAFGILEQNPCVFENMTFFENIsfFADNASVREMVIT--SARVCRCESFIKNHPLSYDA---PVGR 1139
Cdd:TIGR02633 64 GSPLKASNIRDTeRAGIVIIHQELTLVPELSVAENI--FLGNEITLPGGRMayNAMYLRAKNLLRELQLDADNvtrPVGD 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1624762192 1140 LSAGERQRLALARALvSSRAgsGLFLLDEPTAHLDgHSEgcvEEALAEFMR--ARGGSTAIIISHR 1203
Cdd:TIGR02633 142 YGGGQQQLVEIAKAL-NKQA--RLLILDEPSSSLT-EKE---TEILLDIIRdlKAHGVACVYISHK 200
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
955-1220 |
7.57e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 52.33 E-value: 7.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYpqlhhNIKNGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDENfnnmiwmn 1033
Cdd:PRK13634 3 ITFQKVEHRY-----QYKTPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSgTVTIGER-------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1034 ceelinifrycylELSLPLPNKEDSAniirldgipiacfsttfLRKAFGILEQNPcvfENMTFFE----NISFFADNASV 1109
Cdd:PRK13634 70 -------------VITAGKKNKKLKP-----------------LRKKVGIVFQFP---EHQLFEEtvekDICFGPMNFGV 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1110 ---------REMVitsARVCRCESFIKNHPLSydapvgrLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGC 1180
Cdd:PRK13634 117 seedakqkaREMI---ELVGLPEELLARSPFE-------LSGGQMRRVAIAGVLAME---PEVLVLDEPTAGLDPKGRKE 183
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1624762192 1181 VEEALAEFMRaRGGSTAIIISHR-PSALRLAGRVVLLGDGG 1220
Cdd:PRK13634 184 MMEMFYKLHK-EKGLTTVLVTHSmEDAARYADQIVVMHKGT 223
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
980-1228 |
8.31e-07 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 51.62 E-value: 8.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDEnfnNMIWMnceelinifrycyLELSLPLpNKEDS 1058
Cdd:COG1134 42 LKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSgRVEVNG---RVSAL-------------LELGAGF-HPELT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1059 A--NII---RLDGipiacFSTTFLRKAFG-ILEqnpcvfenmtffenisfFADnasvremvitsarvcrCESFIknhpls 1132
Cdd:COG1134 105 GreNIYlngRLLG-----LSRKEIDEKFDeIVE-----------------FAE----------------LGDFI------ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 yDAPVGRLSAGERQRLALAralVSSRAGSGLFLLDEPTAHLDGH-SEGCvEEALAEFMRArgGSTAIIISHRPSALR-LA 1210
Cdd:COG1134 141 -DQPVKTYSSGMRARLAFA---VATAVDPDILLVDEVLAVGDAAfQKKC-LARIRELRES--GRTVIFVSHSMGAVRrLC 213
|
250
....*....|....*...
gi 1624762192 1211 GRVVLLgDGGRSMYEGPP 1228
Cdd:COG1134 214 DRAIWL-EKGRLVMDGDP 230
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
1065-1220 |
1.09e-06 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 53.29 E-value: 1.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1065 DGIPI-ACFSTTFLRKAFGILEQNPCVFE--NMTFFENISFFADNASVREMVITsarvcRCESFIKNHPLSydAPVGRLS 1141
Cdd:PRK00635 739 TSIPCpSCLGKRFLPQVLEVRYKGKNIADilEMTAYEAEKFFLDEPSIHEKIHA-----LCSLGLDYLPLG--RPLSSLS 811
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1142 AGERQRLALARALVSSRAGSGLFLLDEPTAHLDGHSEGCVEEALAEFMRArgGSTAIIISHRPSALRLAGRVVLLG-DGG 1220
Cdd:PRK00635 812 GGEIQRLKLAYELLAPSKKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQ--GHTVVIIEHNMHVVKVADYVLELGpEGG 889
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
1137-1204 |
1.63e-06 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 49.28 E-value: 1.63e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1624762192 1137 VGRLSAGERQRLALARAL-VSSRAGSGLFLLDEPTAHLDGHSEGCVEEALAEfmRARGGSTAIIISHRP 1204
Cdd:cd03227 75 RLQLSGGEKELSALALILaLASLKPRPLYILDEIDRGLDPRDGQALAEAILE--HLVKGAQVIVITHLP 141
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
971-1234 |
1.92e-06 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 52.42 E-value: 1.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 971 IKNGSLMLtLYDFTAKFRAGEITALIGETGSGKSTIMRLLKrmydpvrtikidENFNNMIWMNCEELINifrycylelsl 1050
Cdd:TIGR00956 771 IKKEKRVI-LNNVDGWVKPGTLTALMGASGAGKTTLLNVLA------------ERVTTGVITGGDRLVN----------- 826
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1051 plpnkedsaniirldGIPIacfSTTFLRKAfGILEQNPCVFENMTffenisffadnasVREMVITSARVCRCESFIKNHP 1130
Cdd:TIGR00956 827 ---------------GRPL---DSSFQRSI-GYVQQQDLHLPTST-------------VRESLRFSAYLRQPKSVSKSEK 874
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 LSY--------------DAPVGR----LSAGERQRLALARALVSsRAGSGLFLlDEPTAHLDGHSEGcveeALAEFMR-- 1190
Cdd:TIGR00956 875 MEYveevikllemesyaDAVVGVpgegLNVEQRKRLTIGVELVA-KPKLLLFL-DEPTSGLDSQTAW----SICKLMRkl 948
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1624762192 1191 ARGGSTAIIISHRPSALRLA--GRVVLLGDGGRSMYEGPpsgLGKG 1234
Cdd:TIGR00956 949 ADHGQAILCTIHQPSAILFEefDRLLLLQKGGQTVYFGD---LGEN 991
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
1131-1226 |
1.94e-06 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 49.24 E-value: 1.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1131 LSYDAPVGRLSAGERQRLALARALVSSRAGSgLFLLDEPTAHLDgHSEgcVEEALAEFMRARG-GSTAIIISHRPSALRL 1209
Cdd:cd03238 79 LTLGQKLSTLSGGELQRVKLASELFSEPPGT-LFILDEPSTGLH-QQD--INQLLEVIKGLIDlGNTVILIEHNLDVLSS 154
|
90 100
....*....|....*....|..
gi 1624762192 1210 AGRVVLLG-----DGGRSMYEG 1226
Cdd:cd03238 155 ADWIIDFGpgsgkSGGKVVFSG 176
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
990-1231 |
2.49e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 50.50 E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMRLLKRMYDPVRtikidenfnnmiwmnceelinifrycylelslplpnkedsaNIIRLDGIPI 1069
Cdd:PRK13647 31 GSKTALLGPNGAGKSTLLLHLNGIYLPQR-----------------------------------------GRVKVMGREV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1070 ACFSTTFLRKAFGILEQNP--CVFeNMTFFENISFFADN-----ASVREMVITSARVCRCESFiknhplsYDAPVGRLSA 1142
Cdd:PRK13647 70 NAENEKWVRSKVGLVFQDPddQVF-SSTVWDDVAFGPVNmgldkDEVERRVEEALKAVRMWDF-------RDKPPYHLSY 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1143 GERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRArgGSTAIIISHRPS-ALRLAGRVVLLGDgGR 1221
Cdd:PRK13647 142 GQKKRVAIAGVLAMD---PDVIVLDEPMAYLDPRGQETLMEILDRLHNQ--GKTVIVATHDVDlAAEWADQVIVLKE-GR 215
|
250
....*....|
gi 1624762192 1222 SMYEGPPSGL 1231
Cdd:PRK13647 216 VLAEGDKSLL 225
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
980-1207 |
3.22e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 51.83 E-value: 3.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMydpvrtikidenfnnmiwMNCEELINIfrycylelslplpnkedsa 1059
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL------------------LSTEGEIQI------------------- 1277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 niirlDGIPIACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASvrEMVITSARVCRCESFIKNHP--LSYDAPV 1137
Cdd:TIGR01271 1278 -----DGVSWNSVTLQTWRKAFGVIPQKVFIFSG-TFRKNLDPYEQWSD--EEIWKVAEEVGLKSVIEQFPdkLDFVLVD 1349
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1138 GR--LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfmrARGGSTAIIISHRPSAL 1207
Cdd:TIGR01271 1350 GGyvLSNGHKQLMCLARSILSK---AKILLLDEPSAHLDPVTLQIIRKTLKQ---SFSNCTVILSEHRVEAL 1415
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
989-1226 |
4.46e-06 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 49.63 E-value: 4.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 989 AGEITALIGETGSGKSTIMRLLKRMYDPVRTIKidenfnnmiwmnceelinifryCYLELslpLPNKEDSANIIRLDgip 1068
Cdd:PRK09984 29 HGEMVALLGPSGSGKSTLLRHLSGLITGDKSAG----------------------SHIEL---LGRTVQREGRLARD--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1069 iacfsttfLRKAFGileQNPCVFENMTFFENISffadnasVREMVITSARVCR-----CESFI----KNHPLSYDAPVG- 1138
Cdd:PRK09984 81 --------IRKSRA---NTGYIFQQFNLVNRLS-------VLENVLIGALGSTpfwrtCFSWFtreqKQRALQALTRVGm 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 ---------RLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGSTAIIISHRPSALRL 1209
Cdd:PRK09984 143 vhfahqrvsTLSGGQQQRVAIARALMQQ---AKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRY 219
|
250
....*....|....*..
gi 1624762192 1210 AGRVVLLGDgGRSMYEG 1226
Cdd:PRK09984 220 CERIVALRQ-GHVFYDG 235
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
980-1219 |
7.51e-06 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 48.86 E-value: 7.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnNMIWMNCEELINIFRYcYLELSlplpnKEDSA 1059
Cdd:PRK11124 18 LFDITLDCPQGETLVLLGPSGAGKSSLLRVL-----------------NLLEMPRSGTLNIAGN-HFDFS-----KTPSD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1060 NIIRLdgipiacfsttfLRKAFGILEQNPCVFENMTFFEN-------ISFFADNASVREMVITSARVcRCESFIKNHPLs 1132
Cdd:PRK11124 75 KAIRE------------LRRNVGMVFQQYNLWPHLTVQQNlieapcrVLGLSKDQALARAEKLLERL-RLKPYADRFPL- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1133 ydapvgRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPS-ALRLAG 1211
Cdd:PRK11124 141 ------HLSGGQQQRVAIARALMMEPQ---VLLFDEPTAALDPEITAQIVSIIREL--AETGITQVIVTHEVEvARKTAS 209
|
....*...
gi 1624762192 1212 RVVLLGDG 1219
Cdd:PRK11124 210 RVVYMENG 217
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1062-1174 |
8.94e-06 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 48.49 E-value: 8.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1062 IRLDGIPIacfstTFL----RKAFGI--LEQNPCVFENMTFFENIsffadnASVREMVITSARVC--RCESFIKNHPLSY 1133
Cdd:COG1137 60 IFLDGEDI-----THLpmhkRARLGIgyLPQEASIFRKLTVEDNI------LAVLELRKLSKKEReeRLEELLEEFGITH 128
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1624762192 1134 --DAPVGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD 1174
Cdd:COG1137 129 lrKSKAYSLSGGERRRVEIARALATNPK---FILLDEPFAGVD 168
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
990-1231 |
1.02e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 48.94 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMRLLKRMYdpvrtikidenfnnmiwmnceelinifrycylelslplpnkEDSANIIRLDGIPI 1069
Cdd:PRK13642 33 GEWVSIIGQNGSGKSTTARLIDGLF-----------------------------------------EEFEGKVKIDGELL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1070 ACFSTTFLRKAFGILEQNP-CVFENMTFFENISFFADNASV-REMVITSARvcrcESFIKNHPLSYDA-PVGRLSAGERQ 1146
Cdd:PRK13642 72 TAENVWNLRRKIGMVFQNPdNQFVGATVEDDVAFGMENQGIpREEMIKRVD----EALLAVNMLDFKTrEPARLSGGQKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1147 RLALArALVSSRagSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPSALRLAGRVVLLgDGGRSMYEG 1226
Cdd:PRK13642 148 RVAVA-GIIALR--PEIIILDESTSMLDPTGRQEIMRVIHE-IKEKYQLTVLSITHDLDEAASSDRILVM-KAGEIIKEA 222
|
....*
gi 1624762192 1227 PPSGL 1231
Cdd:PRK13642 223 APSEL 227
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
988-1219 |
1.05e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 49.52 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPvrtikidenfnnmiwmnceelinifrycylelslplpnkedSANIIRLDGI 1067
Cdd:PRK11288 28 RAGQVHALMGENGAGKSTLLKILSGNYQP-----------------------------------------DAGSILIDGQ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIAcFSTTflRKAFG----ILEQNPCVFENMTFFENISF--FADNASV--REMVITSARVCRCESFIKNHPlsyDAPVGR 1139
Cdd:PRK11288 67 EMR-FAST--TAALAagvaIIYQELHLVPEMTVAENLYLgqLPHKGGIvnRRLLNYEAREQLEHLGVDIDP---DTPLKY 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALvsSRaGSGLFLLDEPTAHLDgHSEGCVEEALAEFMRARGgsTAII-ISHRPSAL-RLAGRVVLLG 1217
Cdd:PRK11288 141 LSIGQRQMVEIAKAL--AR-NARVIAFDEPTSSLS-AREIEQLFRVIRELRAEG--RVILyVSHRMEEIfALCDAITVFK 214
|
..
gi 1624762192 1218 DG 1219
Cdd:PRK11288 215 DG 216
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1129-1202 |
1.13e-05 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 49.56 E-value: 1.13e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624762192 1129 HPLSYDAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMrarggSTAIIISH 1202
Cdd:PRK11147 430 HPKRAMTPVKALSGGERNRLLLARLFLKP---SNLLILDEPTNDLDVETLELLEELLDSYQ-----GTVLLVSH 495
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
990-1225 |
1.30e-05 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 48.31 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMRLLKRMydpvrtikidenfnnmiwMNCEELINIfrycylelslplpnkedsaniirlDGIPI 1069
Cdd:cd03289 30 GQRVGLLGRTGSGKSTLLSAFLRL------------------LNTEGDIQI------------------------DGVSW 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1070 ACFSTTFLRKAFGILEQNPCVFENmTFFENISFFADNASvrEMVITSARVCRCESFIKNHP------LSYDAPVgrLSAG 1143
Cdd:cd03289 68 NSVPLQKWRKAFGVIPQKVFIFSG-TFRKNLDPYGKWSD--EEIWKVAEEVGLKSVIEQFPgqldfvLVDGGCV--LSHG 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1144 ERQRLALARALVSsraGSGLFLLDEPTAHLDGHSEGCVEEALAEfmrARGGSTAIIISHRPSALRLAGRVVLLGDGGRSM 1223
Cdd:cd03289 143 HKQLMCLARSVLS---KAKILLLDEPSAHLDPITYQVIRKTLKQ---AFADCTVILSEHRIEAMLECQRFLVIEENKVRQ 216
|
..
gi 1624762192 1224 YE 1225
Cdd:cd03289 217 YD 218
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1074-1202 |
1.30e-05 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 48.17 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1074 TTFLRKAFGILEqnPCVFENMTFFENISF-----FAD-NASVREMVITSARVCRCESFIKN---HPLS----YDAPVGRL 1140
Cdd:cd03237 39 TTFIKMLAGVLK--PDEGDIEIELDTVSYkpqyiKADyEGTVRDLLSSITKDFYTHPYFKTeiaKPLQieqiLDREVPEL 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1141 SAGERQRLALARALvsSRAGSgLFLLDEPTAHLDGHSEGCVEEALAEFMRaRGGSTAIIISH 1202
Cdd:cd03237 117 SGGELQRVAIAACL--SKDAD-IYLLDEPSAYLDVEQRLMASKVIRRFAE-NNEKTAFVVEH 174
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
955-1219 |
1.42e-05 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 47.53 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 955 IDFYQVCFVYP------QLHHNIKNGSLMLTLYDFTA------KFRAGEITALIGETGSGKSTIMRLLKRMYDPvrtiki 1022
Cdd:cd03220 1 IELENVSKSYPtykggsSSLKKLGILGRKGEVGEFWAlkdvsfEVPRGERIGLIGRNGAGKSTLLRLLAGIYPP------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1023 denfnnmiwmnceelinifrycylelslplpnkeDSANIIRLDGI--PIAcFSTTFlrkafgileqNPcvfeNMTFFENI 1100
Cdd:cd03220 75 ----------------------------------DSGTVTVRGRVssLLG-LGGGF----------NP----ELTGRENI 105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1101 SFFAD--NASVREMvitSARVCRCESF--IKNHplsYDAPVGRLSAGERQRLALAralVSSRAGSGLFLLDEPTAHLDGH 1176
Cdd:cd03220 106 YLNGRllGLSRKEI---DEKIDEIIEFseLGDF---IDLPVKTYSSGMKARLAFA---IATALEPDILLIDEVLAVGDAA 176
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1624762192 1177 -SEGCvEEALAEFMraRGGSTAIIISHRPSALR-LAGRVVLLGDG 1219
Cdd:cd03220 177 fQEKC-QRRLRELL--KQGKTVILVSHDPSSIKrLCDRALVLEKG 218
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1134-1202 |
2.03e-05 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 47.15 E-value: 2.03e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGstAIIISH 1202
Cdd:PRK13543 132 DTLVRQLSAGQKKRLALARLWLSP---APLWLLDEPYANLDLEGITLVNRMISAHLRGGGA--ALVTTH 195
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
982-1174 |
2.50e-05 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 47.20 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAKFRAGEITALIGETGSGKST----IMRLLKRmyDPVRTIKIDENfnnmiwmnceelINIfrycylelsLPLPNKEd 1057
Cdd:PRK10895 21 DVSLTVNSGEIVGLLGPNGAGKTTtfymVVGIVPR--DAGNIIIDDED------------ISL---------LPLHARA- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1058 saniirldgipiacfsttflRKAFGILEQNPCVFENMTFFENISFFADnasVREMVITSARVCRCESFIKNHPLSY--DA 1135
Cdd:PRK10895 77 --------------------RRGIGYLPQEASIFRRLSVYDNLMAVLQ---IRDDLSAEQREDRANELMEEFHIEHlrDS 133
|
170 180 190
....*....|....*....|....*....|....*....
gi 1624762192 1136 PVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLD 1174
Cdd:PRK10895 134 MGQSLSGGERRRVEIARALA---ANPKFILLDEPFAGVD 169
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1134-1221 |
3.41e-05 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 46.78 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDghsegcveeALA-EFMR-------ARGGSTAIIISHR-P 1204
Cdd:COG4525 129 RRRIWQLSGGMRQRVGIARALAAD---PRFLLMDEPFGALD---------ALTrEQMQellldvwQRTGKGVFLITHSvE 196
|
90
....*....|....*...
gi 1624762192 1205 SALRLAGRVVLLGDG-GR 1221
Cdd:COG4525 197 EALFLATRLVVMSPGpGR 214
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
1139-1212 |
5.67e-05 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 45.93 E-value: 5.67e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624762192 1139 RLSAGERQRLALARALvSSRagSGLFLLDEPTAHLDGHSEGCVEEALAEFMRaRGGSTAIIISHRPsalRLAGR 1212
Cdd:PRK10584 146 QLSGGEQQRVALARAF-NGR--PDVLFADEPTGNLDRQTGDKIADLLFSLNR-EHGTTLILVTHDL---QLAAR 212
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1139-1221 |
6.08e-05 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 46.23 E-value: 6.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1139 RLSAGERQRLALARALVssrAGSGLFLLDEPTAHLDGHSEGCVEEALAEFMRaRGGSTAIIISHR-PSALRLAGRVVLLG 1217
Cdd:PRK11248 128 QLSGGQRQRVGIARALA---ANPQLLLLDEPFGALDAFTREQMQTLLLKLWQ-ETGKQVLLITHDiEEAVFMATELVLLS 203
|
....*
gi 1624762192 1218 DG-GR 1221
Cdd:PRK11248 204 PGpGR 208
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
987-1174 |
6.55e-05 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 45.61 E-value: 6.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 987 FRAGEITALIGETGSGKSTIMrllkrmydpvrtikidenfnNMIwmnceelinifryCYLElslplpnKEDSANIIrLDG 1066
Cdd:cd03218 23 VKQGEIVGLLGPNGAGKTTTF--------------------YMI-------------VGLV-------KPDSGKIL-LDG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 IPIacfsTTF-----LRKAFGILEQNPCVFENMTFFENISffadnASVREMVITSA-RVCRCESFIKNHPLSY--DAPVG 1138
Cdd:cd03218 62 QDI----TKLpmhkrARLGIGYLPQEASIFRKLTVEENIL-----AVLEIRGLSKKeREEKLEELLEEFHITHlrKSKAS 132
|
170 180 190
....*....|....*....|....*....|....*.
gi 1624762192 1139 RLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD 1174
Cdd:cd03218 133 SLSGGERRRVEIARALATNPK---FLLLDEPFAGVD 165
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1090-1221 |
7.09e-05 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 46.38 E-value: 7.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1090 VFEN------MTFFENISFFADNASV-----REMVITSARVCRCESFIKNHPlsydapvgR-LSAGERQRLALARALVSS 1157
Cdd:PRK11650 81 VFQNyalyphMSVRENMAYGLKIRGMpkaeiEERVAEAARILELEPLLDRKP--------ReLSGGQRQRVAMGRAIVRE 152
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1158 RAgsgLFLLDEPTAHLDGhsegcveeALAEFMRA-------RGGSTAIIISH-RPSALRLAGRVVLLgDGGR 1221
Cdd:PRK11650 153 PA---VFLFDEPLSNLDA--------KLRVQMRLeiqrlhrRLKTTSLYVTHdQVEAMTLADRVVVM-NGGV 212
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
988-1012 |
8.91e-05 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 46.20 E-value: 8.91e-05
10 20
....*....|....*....|....*....
gi 1624762192 988 RAGEITALIGETGSGKST----IMRLLKR 1012
Cdd:COG0444 29 RRGETLGLVGESGSGKSTlaraILGLLPP 57
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
953-1219 |
1.04e-04 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 46.50 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 953 KSIDFYQVCFVYPQlhHNIKNGSLMLTLydftakfRAGEITALIGETGSGKSTIMRLLKRMYDPVrtikidenfnnmiwm 1032
Cdd:PRK10522 321 QTLELRNVTFAYQD--NGFSVGPINLTI-------KRGELLFLIGGNGSGKSTLAMLLTGLYQPQ--------------- 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1033 nceelinifrycylelslplpnkedsANIIRLDGIPIACFSTTFLRKAFGileqnpCVFENMTFFENI----SFFADNAS 1108
Cdd:PRK10522 377 --------------------------SGEILLDGKPVTAEQPEDYRKLFS------AVFTDFHLFDQLlgpeGKPANPAL 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1109 VREMVITSARVCRCEsfIKNHPLSYDapvgRLSAGERQRLALARALVSSRagsGLFLLDEPTAHLDGHSEGCVEEALAEF 1188
Cdd:PRK10522 425 VEKWLERLKMAHKLE--LEDGRISNL----KLSKGQKKRLALLLALAEER---DILLLDEWAADQDPHFRREFYQVLLPL 495
|
250 260 270
....*....|....*....|....*....|.
gi 1624762192 1189 MRARgGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PRK10522 496 LQEM-GKTIFAISHDDHYFIHADRLLEMRNG 525
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
1093-1220 |
1.09e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 46.54 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1093 NMTFFENISFFADNASVREMVITSARVcrcesfiknhPLSYdAPVGR----LSAGERQRLALARALVSSRAGSGLFLLDE 1168
Cdd:TIGR00630 790 DMTVEEAYEFFEAVPSISRKLQTLCDV----------GLGY-IRLGQpattLSGGEAQRIKLAKELSKRSTGRTLYILDE 858
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1624762192 1169 PTAHLdgHSEGcVEEALAEFMR-ARGGSTAIIISHRPSALRLAGRVVLLG-DGG 1220
Cdd:TIGR00630 859 PTTGL--HFDD-IKKLLEVLQRlVDKGNTVVVIEHNLDVIKTADYIIDLGpEGG 909
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
1095-1224 |
1.12e-04 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 45.62 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1095 TFFENISFFADNASVREMVITSArvCRCESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSragSGLFLLDEPT 1170
Cdd:cd03291 113 TIKENIIFGVSYDEYRYKSVVKA--CQLEEDITKFPEKDNTVLGEggitLSGGQRARISLARAVYKD---ADLYLLDSPF 187
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1624762192 1171 AHLDGHSEGCV-EEALAEFMRARggsTAIIISHRPSALRLAGRVVLLGDGGRSMY 1224
Cdd:cd03291 188 GYLDVFTEKEIfESCVCKLMANK---TRILVTSKMEHLKKADKILILHEGSSYFY 239
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1136-1202 |
1.27e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 46.32 E-value: 1.27e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1624762192 1136 PVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFmrargGSTAIIISH 1202
Cdd:PRK10636 146 PVSDFSGGWRMRLNLAQALICR---SDLLLLDEPTNHLDLDAVIWLEKWLKSY-----QGTLILISH 204
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1087-1207 |
1.37e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 44.56 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1087 NPcvfeNMTFFENiSFFADNASVREMVITSArvcrCESFIKNHPLSYdaPVGRLSAGERQRLALARALVSsraGSGLFLL 1166
Cdd:PRK13540 86 NP----YLTLREN-CLYDIHFSPGAVGITEL----CRLFSLEHLIDY--PCGLLSSGQKRQVALLRLWMS---KAKLWLL 151
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1624762192 1167 DEPTAHLDGHSEGCVEEALAEFmRARGGSTaIIISHRPSAL 1207
Cdd:PRK13540 152 DEPLVALDELSLLTIITKIQEH-RAKGGAV-LLTSHQDLPL 190
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1095-1224 |
1.37e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 46.44 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1095 TFFENISFfadNASVREMVITSA-RVCRCESFIKNHPLSYDAPVGR----LSAGERQRLALARALVSSragSGLFLLDEP 1169
Cdd:TIGR01271 502 TIKDNIIF---GLSYDEYRYTSViKACQLEEDIALFPEKDKTVLGEggitLSGGQRARISLARAVYKD---ADLYLLDSP 575
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1624762192 1170 TAHLDGHSEGCV-EEALAEFMRARggsTAIIISHRPSALRLAGRVVLLGDGGRSMY 1224
Cdd:TIGR01271 576 FTHLDVVTEKEIfESCLCKLMSNK---TRILVTSKLEHLKKADKILLLHEGVCYFY 628
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
1140-1219 |
1.41e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 46.48 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1140 LSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRARGGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:TIGR00957 761 LSGGQKQRVSLARAVYSN---ADIYLFDDPLSAVDAHVGKHIFEHVIGPEGVLKNKTRILVTHGISYLPQVDVIIVMSGG 837
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
1073-1219 |
1.67e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 46.12 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1073 STTFLRKAFGILEQNPCVFeNMTFFENISFFADNASVREMVITSARVCRCE-SFIKNHPLSYDAPVG-RLSAGERQRLAL 1150
Cdd:PLN03232 673 SSVVIRGSVAYVPQVSWIF-NATVRENILFGSDFESERYWRAIDVTALQHDlDLLPGRDLTEIGERGvNISGGQKQRVSM 751
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1624762192 1151 ARALVSSragSGLFLLDEPTAHLDGHS-----EGCVEEALAefmrargGSTAIIISHRPSALRLAGRVVLLGDG 1219
Cdd:PLN03232 752 ARAVYSN---SDIYIFDDPLSALDAHVahqvfDSCMKDELK-------GKTRVLVTNQLHFLPLMDRIILVSEG 815
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1136-1208 |
2.20e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 45.55 E-value: 2.20e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1624762192 1136 PVGRLSAGERQRLALArALVSSRagSGLFLLDEPTAHLDGHSEGCVEEALAEFMRArggstAIIISHRPSALR 1208
Cdd:PRK10636 427 ETRRFSGGEKARLVLA-LIVWQR--PNLLLLDEPTNHLDLDMRQALTEALIDFEGA-----LVVVSHDRHLLR 491
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
1141-1202 |
4.01e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 44.85 E-value: 4.01e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1141 SAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEFMRarggsTAIIISH 1202
Cdd:PLN03073 346 SGGWRMRIALARALFIE---PDLLLLDEPTNHLDLHAVLWLETYLLKWPK-----TFIVVSH 399
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
988-1218 |
4.12e-04 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 44.41 E-value: 4.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLKRMYDPVR---TIKIDENFNNMiwmnceelinifrycylelSLPLPNKEDSAniirl 1064
Cdd:TIGR03269 308 KEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSgevNVRVGDEWVDM-------------------TKPGPDGRGRA----- 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1065 dgipiacfsttflRKAFGILEQNPCVFENMTFFEN----ISF-FADNASVREMVITSARVC----RCESFIKNHPlsyda 1135
Cdd:TIGR03269 364 -------------KRYIGILHQEYDLYPHRTVLDNlteaIGLeLPDELARMKAVITLKMVGfdeeKAEEILDKYP----- 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1136 pvGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALaefMRARG--GSTAIIISH----------R 1203
Cdd:TIGR03269 426 --DELSEGERHRVALAQVLIKE---PRIVILDEPTGTMDPITKVDVTHSI---LKAREemEQTFIIVSHdmdfvldvcdR 497
|
250
....*....|....*
gi 1624762192 1204 PSALRlAGRVVLLGD 1218
Cdd:TIGR03269 498 AALMR-DGKIVKIGD 511
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1132-1219 |
4.84e-04 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 44.05 E-value: 4.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1132 SYDAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALaeFMRARGGSTAIIISHR-PSALRLA 1210
Cdd:TIGR02633 396 SPFLPIGRLSGGNQQKAVLAKMLLTN---PRVLILDEPTRGVDVGAKYEIYKLI--NQLAQEGVAIIVVSSElAEVLGLS 470
|
....*....
gi 1624762192 1211 GRVVLLGDG 1219
Cdd:TIGR02633 471 DRVLVIGEG 479
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
990-1216 |
5.01e-04 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 43.84 E-value: 5.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMRLLKRMYDPVRTIKID-ENFNNMIWMNCEEL-INI-FRYCYLELSLPLPNKEDSANIIRLdg 1066
Cdd:COG3593 23 DDLTVLVGENNSGKSSILEALRLLLGPSSSRKFDeEDFYLGDDPDLPEIeIELtFGSLLSRLLRLLLKEEDKEELEEA-- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 ipIACFSTTF---LRKAFGILEQnpcVFENMTFFENISFFAdNASVREMVITSARVcrcesFIKNhplSYDAPVGRLSAG 1143
Cdd:COG3593 101 --LEELNEELkeaLKALNELLSE---YLKELLDGLDLELEL-SLDELEDLLKSLSL-----RIED---GKELPLDRLGSG 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1624762192 1144 ERQRLALA----RALVSSRAGSGLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPSALRLAG--RVVLL 1216
Cdd:COG3593 167 FQRLILLAllsaLAELKRAPANPILLIEEPEAHLHPQAQRRLLKLLKEL--SEKPNQVIITTHSPHLLSEVPleNIRRL 243
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
953-1023 |
5.25e-04 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 44.02 E-value: 5.25e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 953 KSIDFYQVCFVYPQlhhniKNGSLMLTLYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKID 1023
Cdd:COG4615 326 QTLELRGVTYRYPG-----EDGDEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESgEILLD 392
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
990-1226 |
5.94e-04 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 44.10 E-value: 5.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 990 GEITALIGETGSGKSTIMRLLK-RMYDpvrtikidENFNNMIWMNceelinifrycylelslplpNKEDSANIIrldgip 1068
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAgRIQG--------NNFTGTILAN--------------------NRKPTKQIL------ 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1069 iacfsttflrKAFGILEQNPCVFENMTFFENISFFA-----------DNASVREMVITSARVCRCE------SFIKNhpl 1131
Cdd:PLN03211 140 ----------KRTGFVTQDDILYPHLTVRETLVFCSllrlpksltkqEKILVAESVISELGLTKCEntiignSFIRG--- 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1132 sydapvgrLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEFmrARGGSTAIIISHRPSA--LRL 1209
Cdd:PLN03211 207 --------ISGGERKRVSIAHEMLINPS---LLILDEPTSGLDATAAYRLVLTLGSL--AQKGKTIVTSMHQPSSrvYQM 273
|
250
....*....|....*..
gi 1624762192 1210 AGRVVLLGDgGRSMYEG 1226
Cdd:PLN03211 274 FDSVLVLSE-GRCLFFG 289
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
1137-1231 |
6.37e-04 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 43.55 E-value: 6.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1137 VGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISHRPSALRLAGRVVLL 1216
Cdd:PRK11432 134 VDQISGGQQQRVALARALILK---PKVLLFDEPLSNLDANLRRSMREKIRE-LQQQFNITSLYVTHDQSEAFAVSDTVIV 209
|
90
....*....|....*
gi 1624762192 1217 GDGGRSMYEGPPSGL 1231
Cdd:PRK11432 210 MNKGKIMQIGSPQEL 224
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
980-1219 |
6.78e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 43.15 E-value: 6.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMYDP----VRTIKIDENFNNMIWMNCEELINIfrycylELSLPLPNK 1055
Cdd:PRK13651 23 LDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPdtgtIEWIFKDEKNKKKTKEKEKVLEKL------VIQKTRFKK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1056 EDSANIIRldgipiacfsttflrKAFGILEQnpcvFENMTFFE-----NISFFADNASV-REMVITSAR-----VCRCES 1124
Cdd:PRK13651 97 IKKIKEIR---------------RRVGVVFQ----FAEYQLFEqtiekDIIFGPVSMGVsKEEAKKRAAkyielVGLDES 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1125 FIKNHPLSydapvgrLSAGERQRLALARALvssrAGSGLFL-LDEPTAHLDGHSegcVEEALAEFMRA-RGGSTAIIISH 1202
Cdd:PRK13651 158 YLQRSPFE-------LSGGQKRRVALAGIL----AMEPDFLvFDEPTAGLDPQG---VKEILEIFDNLnKQGKTIILVTH 223
|
250
....*....|....*...
gi 1624762192 1203 R-PSALRLAGRVVLLGDG 1219
Cdd:PRK13651 224 DlDNVLEWTKRTIFFKDG 241
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
987-1228 |
7.26e-04 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 44.23 E-value: 7.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 987 FRAGEITALIGETGSGKSTIMRLLKRMYDPVRTikidenfnnmiwmnceelinifrycylelSLPLPNKEDSANiirLDG 1066
Cdd:TIGR01257 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSG-----------------------------TVLVGGKDIETN---LDA 1000
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1067 IpiacfsttflRKAFGILEQNPCVFENMTFFENISFFAdnaSVREMVITSARVcRCESFIKNHPLSY--DAPVGRLSAGE 1144
Cdd:TIGR01257 1001 V----------RQSLGMCPQHNILFHHLTVAEHILFYA---QLKGRSWEEAQL-EMEAMLEDTGLHHkrNEEAQDLSGGM 1066
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1145 RQRLALARALVSSragSGLFLLDEPTAHLDGHSEGCVEEALaefMRARGGSTAIIISHRPSALRLAGRVVLLGDGGRSMY 1224
Cdd:TIGR01257 1067 QRKLSVAIAFVGD---AKVVVLDEPTSGVDPYSRRSIWDLL---LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYC 1140
|
....
gi 1624762192 1225 EGPP 1228
Cdd:TIGR01257 1141 SGTP 1144
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
1123-1174 |
7.69e-04 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 43.32 E-value: 7.69e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1624762192 1123 ESFIKNHPLSydapvgrLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD 1174
Cdd:PRK11144 119 EPLLDRYPGS-------LSGGEKQRVAIGRALLTAPE---LLLMDEPLASLD 160
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1134-1174 |
8.71e-04 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 42.41 E-value: 8.71e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVSSragSGLFLLDEPTAHLD 1174
Cdd:PRK09544 115 DAPMQKLSGGETQRVLLARALLNR---PQLLVLDEPTQGVD 152
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
1140-1170 |
8.89e-04 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 43.48 E-value: 8.89e-04
10 20 30
....*....|....*....|....*....|...
gi 1624762192 1140 LSAGERQRLALARALvsSRAGSG--LFLLDEPT 1170
Cdd:COG0178 827 LSGGEAQRVKLASEL--SKRSTGktLYILDEPT 857
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
980-1014 |
1.51e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 42.47 E-value: 1.51e-03
10 20 30
....*....|....*....|....*....|....*
gi 1624762192 980 LYDFTAKFRAGEITALIGETGSGKSTIMRLLKRMY 1014
Cdd:NF040905 17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVY 51
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
988-1221 |
1.80e-03 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 41.99 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKSTIMRLLkrmydpvrtikidenfnNMiwmnceelinifrycyLElslplpnKEDSANIIrLDGI 1067
Cdd:COG1135 29 EKGEIFGIIGYSGAGKSTLIRCI-----------------NL----------------LE-------RPTSGSVL-VDGV 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1068 PIACFSTTFLRKA-------FgileQNPCVFENMTFFENISF---FAD------NASVREM---VITSARvcrcesfIKN 1128
Cdd:COG1135 68 DLTALSERELRAArrkigmiF----QHFNLLSSRTVAENVALpleIAGvpkaeiRKRVAELlelVGLSDK-------ADA 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1129 HPlsydapvGRLSAGERQRLALARALVSSRAgsgLFLLDEPTAHLDGHSEGCVEEALAEfMRARGGSTAIIISH-----R 1203
Cdd:COG1135 137 YP-------SQLSGGQKQRVGIARALANNPK---VLLCDEATSALDPETTRSILDLLKD-INRELGLTIVLITHemdvvR 205
|
250
....*....|....*...
gi 1624762192 1204 psalRLAGRVVLLgDGGR 1221
Cdd:COG1135 206 ----RICDRVAVL-ENGR 218
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
988-1174 |
1.89e-03 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 42.36 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 988 RAGEITALIGETGSGKST----IMRLLkrmydpvrtikidenfnnmiwmnceelinifrycylelslplpnkeDSANIIR 1063
Cdd:COG4172 310 RRGETLGLVGESGSGKSTlglaLLRLI----------------------------------------------PSEGEIR 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1064 LDGIPIACFSTT---FLRKAFGILEQNP------------CVFENMTFFENIsffADNASVREMVITS-ARVcrcesfik 1127
Cdd:COG4172 344 FDGQDLDGLSRRalrPLRRRMQVVFQDPfgslsprmtvgqIIAEGLRVHGPG---LSAAERRARVAEAlEEV-------- 412
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1624762192 1128 nhPLSYDApVGR----LSAGERQRLALARALVSSRAgsgLFLLDEPTAHLD 1174
Cdd:COG4172 413 --GLDPAA-RHRypheFSGGQRQRIAIARALILEPK---LLVLDEPTSALD 457
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1134-1219 |
2.38e-03 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 41.06 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPvGRLSAGERQRLALARALVSsraGSGLFLLDEPTAHLDghseGCVEEALAEFMR---ARGGSTAIIISHRPSALR-L 1209
Cdd:PRK11701 147 DLP-TTFSGGMQQRLQIARNLVT---HPRLVFMDEPTGGLD----VSVQARLLDLLRglvRELGLAVVIVTHDLAVARlL 218
|
90
....*....|
gi 1624762192 1210 AGRVVLLGDG 1219
Cdd:PRK11701 219 AHRLLVMKQG 228
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
988-1010 |
2.51e-03 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 41.98 E-value: 2.51e-03
10 20
....*....|....*....|....*..
gi 1624762192 988 RAGEITALIGETGSGKS----TIMRLL 1010
Cdd:COG4172 34 AAGETLALVGESGSGKSvtalSILRLL 60
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
990-1016 |
3.01e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 3.01e-03
|
| AAA_22 |
pfam13401 |
AAA domain; |
985-1023 |
3.43e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 38.86 E-value: 3.43e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1624762192 985 AKFRAGeITALIGETGSGKSTIMRLLKRMYD--PVRTIKID 1023
Cdd:pfam13401 1 IRFGAG-ILVLTGESGTGKTTLLRRLLEQLPevRDSVVFVD 40
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
982-1219 |
3.67e-03 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 41.54 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 982 DFTAkfRAGEITALIGETGSGKSTIMRLLKRMYDPVR-TIKIDENfnnmiwmnceelinifrycylelSLPLPNKEDSan 1060
Cdd:COG1129 272 SFSV--RAGEILGIAGLVGAGRTELARALFGADPADSgEIRLDGK-----------------------PVRIRSPRDA-- 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1061 iIRLdGIpiacfstTFL---RKAFGIleqnpcvFENMTFFENISFFADNASVREMVITSARVCR-CESFIKN---HPLSY 1133
Cdd:COG1129 325 -IRA-GI-------AYVpedRKGEGL-------VLDLSIRENITLASLDRLSRGGLLDRRRERAlAEEYIKRlriKTPSP 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1624762192 1134 DAPVGRLSAGERQRLALARALVssrAGSGLFLLDEPTAHLD-GhsegcveeALAE---FMR--ARGGSTAIIIShrpS-- 1205
Cdd:COG1129 389 EQPVGNLSGGNQQKVVLAKWLA---TDPKVLILDEPTRGIDvG--------AKAEiyrLIRelAAEGKAVIVIS---Sel 454
|
250
....*....|....*.
gi 1624762192 1206 --ALRLAGRVVLLGDG 1219
Cdd:COG1129 455 peLLGLSDRILVMREG 470
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1141-1174 |
3.77e-03 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 41.23 E-value: 3.77e-03
10 20 30
....*....|....*....|....*....|....
gi 1624762192 1141 SAGERQRLALARALVSSRAgsgLFLLDEPTAHLD 1174
Cdd:PRK15134 427 SGGQRQRIAIARALILKPS---LIILDEPTSSLD 457
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1134-1174 |
4.32e-03 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 41.33 E-value: 4.32e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1624762192 1134 DAPVGRLSAGERQRLALARALvsSRAGSgLFLLDEPTAHLD 1174
Cdd:PRK13409 207 DRDISELSGGELQRVAIAAAL--LRDAD-FYFFDEPTSYLD 244
|
|
| |
