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Conserved domains on  [gi|1622827699|ref|XP_028706462|]
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tenascin-N isoform X2 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FReD cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...
 977-1188 2.51e-116

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.


:

Pssm-ID: 238040 [Multi-domain]  Cd Length: 215  Bit Score: 360.02  E-value: 2.51e-116
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  977 PHPSDCSQVQQNSNAASGLYTIYLHGdSSRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTKEFWLGL 1056
Cdd:cd00087      1 PLPRDCSEVLQRGGRTSGVYTIQPPG-SNEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699 1057 DKLHNLTTGTPtrYEVRVDLQT-ANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALSYHNGWKFTTFDRDNDIALSN 1135
Cdd:cd00087     80 EKIHLLTSQGP--YELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGN 157

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699 1136 CALTHHGGWWYKNCHLANPNGRYGETKH----SEGVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:cd00087    158 CAESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRP 214
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
600-980 4.88e-13

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 73.50  E-value: 4.88e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  600 VWAQKGDQESKKTDTKAQTDIDSPQNLVTDWVTENMATVSWDPVQATIDRYVVRYTSAKDGETREVPVGKEQNSTVLTGL 679
Cdd:COG3401     30 GGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNT 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  680 RPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPKNLVTDRVTENTATVSWDLVQATIDRYVVRYTSANGETREVPVGKEQ 759
Cdd:COG3401    110 GLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  760 SSTVLTGLR--PGVEYTVHVWAQKGNQESKKAD----TKAQTEIDSPKNLVTDRVTENMATVSWDPVQAT-IDKYVV-RY 831
Cdd:COG3401    190 TTLVDGGGDiePGTTYYYRVAATDTGGESAPSNevsvTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVyRS 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  832 TSADGETREVPVGKEhSSTVLTGLRPGMEYMVHVWAQKGD-QESKKADT-KAQTEI---DPPRNLRPSAVTQSGGVLTWT 906
Cdd:COG3401    270 NSGDGPFTKVATVTT-TSYTDTGLTNGTTYYYRVTAVDAAgNESAPSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWT 348

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699  907 PPS-AQIHGYILTY-QFPDGTVKEIQLGREDQRFELQGLEQGATYPVSLVAF-KGGLRSRNVSTTLSTVGARFPHPS 980
Cdd:COG3401    349 ASSdADVTGYNVYRsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVdAAGNESAPSEEVSATTASAASGES 425
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 444-526 2.29e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  444 DSPANLVTDRVTENTATISWDPVQAT---IDKYVVHYTSADNQETREVPVGK-EQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  520 ESKKANT 526
Cdd:cd00063     82 ESPPSES 88
fn3 pfam00041
Fibronectin type III domain;
264-342 4.58e-12

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 4.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEP----SSQVDHYFLNYYPLGKELSGKQIRVPKEQHSYEILGLLPGTKYIVTLRNVKKDIF 339
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPppdgNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 1622827699  340 SSP 342
Cdd:pfam00041   82 GPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 533-609 2.30e-10

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 58.01  E-value: 2.30e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   533 DSPKNLVTDRVTENMATVSWDPVQAT-----IDKYMVRYTSADGETREVPVGKEHSSTILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   608 ES 609
Cdd:smart00060   82 EG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 359-434 2.39e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 58.28  E-value: 2.39e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622827699  359 VTEETEHSLDVEWENPS---TEVDYYKLRYGPMTGQEVTEVTVPKSSDPksRYDITGLHPGTEYKITVVPMRGTLEGKP 434
Cdd:cd00063      9 VTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSET--SYTLTGLKPGTEYEFRVRAVNGGGESPP 85
EGF_Tenascin super family cl46594
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 171-197 2.97e-05

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934  Cd Length: 29  Bit Score: 41.90  E-value: 2.97e-05
                           10        20
                   ....*....|....*....|....*..
gi 1622827699  171 CPGACSGHGRCVDGRCLCHEPYVGADC 197
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
EGF_2 pfam07974
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
 236-259 1.05e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.


:

Pssm-ID: 400365  Cd Length: 26  Bit Score: 40.41  E-value: 1.05e-04
                           10        20
                   ....*....|....*....|....*.
gi 1622827699  236 DCSGHGFCD--TGECYCEEGFTGLDC 259
Cdd:pfam07974    1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
EGF_Tenascin super family cl46594
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 202-229 1.33e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934  Cd Length: 29  Bit Score: 37.28  E-value: 1.33e-03
                           10        20
                   ....*....|....*....|....*...
gi 1622827699  202 CPENCSGHGECVRGVCQCHEDFTSEDCS 229
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
 
Name Accession Description Interval E-value
FReD cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...
 977-1188 2.51e-116

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.


Pssm-ID: 238040 [Multi-domain]  Cd Length: 215  Bit Score: 360.02  E-value: 2.51e-116
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  977 PHPSDCSQVQQNSNAASGLYTIYLHGdSSRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTKEFWLGL 1056
Cdd:cd00087      1 PLPRDCSEVLQRGGRTSGVYTIQPPG-SNEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699 1057 DKLHNLTTGTPtrYEVRVDLQT-ANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALSYHNGWKFTTFDRDNDIALSN 1135
Cdd:cd00087     80 EKIHLLTSQGP--YELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGN 157

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699 1136 CALTHHGGWWYKNCHLANPNGRYGETKH----SEGVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:cd00087    158 CAESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRP 214
FBG smart00186
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ...
 978-1188 2.35e-103

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.


Pssm-ID: 214548 [Multi-domain]  Cd Length: 212  Bit Score: 325.00  E-value: 2.35e-103
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   978 HPSDCSQVQQNSNAASGLYTIYLHGdSSRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTKEFWLGLD 1057
Cdd:smart00186    1 LPRDCSDVLQNGGKTSGLYTIYPDG-SSRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  1058 KLHNLTTGTPtrYEVRVDLQ-TANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDA-LSYHNGWKFTTFDRDNDIALSN 1135
Cdd:smart00186   80 NIHLLTSQGK--YELRIDLEdWEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDAsLTYHNGMQFSTYDRDNDKYSGN 157

                           170       180       190       200       210
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1622827699  1136 CALTHHGGWWYKNCHLANPNGRYG-ETKHSEGVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:smart00186  158 CAEEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRP 211
Fibrinogen_C pfam00147
Fibrinogen beta and gamma chains, C-terminal globular domain;
979-1188 6.79e-86

Fibrinogen beta and gamma chains, C-terminal globular domain;


Pssm-ID: 395095 [Multi-domain]  Cd Length: 221  Bit Score: 277.87  E-value: 6.79e-86
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  979 PSDCSQVQQNSNAASGLYTIYLHGDSsRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTK-EFWLGLD 1057
Cdd:pfam00147    2 GRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSPgEFWLGND 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699 1058 KLHNLTTGTPtrYEVRVDLQTAN-ESAYAIYDFFQVASSKERYKLTVGKYRGTAGDAL-------SYHNGWKFTTFDRDN 1129
Cdd:pfam00147   81 KIHLLTKQGP--YVLRIDLEDWNgETVFALYDSFKVTNENDKYRLHVENYIGDAGDALdtagrsmTYHNGMQFSTWDRDN 158

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622827699 1130 DIALSNCALTHHGGWWYKNCHLANPNGRY--GETKHSE-GVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:pfam00147  159 DSPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRP 220
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
600-980 4.88e-13

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 73.50  E-value: 4.88e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  600 VWAQKGDQESKKTDTKAQTDIDSPQNLVTDWVTENMATVSWDPVQATIDRYVVRYTSAKDGETREVPVGKEQNSTVLTGL 679
Cdd:COG3401     30 GGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNT 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  680 RPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPKNLVTDRVTENTATVSWDLVQATIDRYVVRYTSANGETREVPVGKEQ 759
Cdd:COG3401    110 GLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  760 SSTVLTGLR--PGVEYTVHVWAQKGNQESKKAD----TKAQTEIDSPKNLVTDRVTENMATVSWDPVQAT-IDKYVV-RY 831
Cdd:COG3401    190 TTLVDGGGDiePGTTYYYRVAATDTGGESAPSNevsvTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVyRS 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  832 TSADGETREVPVGKEhSSTVLTGLRPGMEYMVHVWAQKGD-QESKKADT-KAQTEI---DPPRNLRPSAVTQSGGVLTWT 906
Cdd:COG3401    270 NSGDGPFTKVATVTT-TSYTDTGLTNGTTYYYRVTAVDAAgNESAPSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWT 348

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699  907 PPS-AQIHGYILTY-QFPDGTVKEIQLGREDQRFELQGLEQGATYPVSLVAF-KGGLRSRNVSTTLSTVGARFPHPS 980
Cdd:COG3401    349 ASSdADVTGYNVYRsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVdAAGNESAPSEEVSATTASAASGES 425
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 621-703 1.27e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.83  E-value: 1.27e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  621 DSPQNLVTDWVTENMATVSWDPVQAT---IDRYVVRYTSAKDGETREVPVGK-EQNSTVLTGLRPGVEYTVHVWAQKGAQ 696
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  697 ESKKADT 703
Cdd:cd00063     82 ESPPSES 88
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 444-526 2.29e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  444 DSPANLVTDRVTENTATISWDPVQAT---IDKYVVHYTSADNQETREVPVGK-EQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  520 ESKKANT 526
Cdd:cd00063     82 ESPPSES 88
fn3 pfam00041
Fibronectin type III domain;
444-522 2.60e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 63.59  E-value: 2.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  444 DSPANLVTDRVTENTATISWDP---VQATIDKYVVHYTSADNQE-TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEpWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ...
gi 1622827699  520 ESK 522
Cdd:pfam00041   81 EGP 83
fn3 pfam00041
Fibronectin type III domain;
264-342 4.58e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 4.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEP----SSQVDHYFLNYYPLGKELSGKQIRVPKEQHSYEILGLLPGTKYIVTLRNVKKDIF 339
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPppdgNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 1622827699  340 SSP 342
Cdd:pfam00041   82 GPP 84
fn3 pfam00041
Fibronectin type III domain;
710-787 1.49e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 61.66  E-value: 1.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  710 DSPKNLVTDRVTENTATVSW---DLVQATIDRYVVRYTSANGET--REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGNQ 784
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ...
gi 1622827699  785 ESK 787
Cdd:pfam00041   81 EGP 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 710-786 1.51e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.48  E-value: 1.51e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   710 DSPKNLVTDRVTENTATVSWDLVQAT-----IDRYVVRYTSANGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGNQ 784
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   785 ES 786
Cdd:smart00060   82 EG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 444-521 1.75e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.09  E-value: 1.75e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   444 DSPANLVTDRVTENTATISWD-PVQATIDKYVVHYT---SADNQETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGYRveyREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   520 ES 521
Cdd:smart00060   82 EG 83
GGGWT_bact NF040941
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ...
 982-1021 2.04e-10

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.


Pssm-ID: 468872 [Multi-domain]  Cd Length: 46  Bit Score: 56.80  E-value: 2.04e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1622827699  982 CSQV-QQNSNAASGLYTIYLHGDSSR-PLQVYCDMDTDGGGW 1021
Cdd:NF040941     2 CWEIlQAGPSAPSGVYWIDPDGMGGLaPFQVYCDMTTDGGGW 43
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 533-609 2.30e-10

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 58.01  E-value: 2.30e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   533 DSPKNLVTDRVTENMATVSWDPVQAT-----IDKYMVRYTSADGETREVPVGKEHSSTILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   608 ES 609
Cdd:smart00060   82 EG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 359-434 2.39e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 58.28  E-value: 2.39e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622827699  359 VTEETEHSLDVEWENPS---TEVDYYKLRYGPMTGQEVTEVTVPKSSDPksRYDITGLHPGTEYKITVVPMRGTLEGKP 434
Cdd:cd00063      9 VTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSET--SYTLTGLKPGTEYEFRVRAVNGGGESPP 85
fn3 pfam00041
Fibronectin type III domain;
359-434 3.01e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.81  E-value: 3.01e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  359 VTEETEHSLDVEWENPST---EVDYYKLRYGPMTGQEV-TEVTVPKSsdpKSRYDITGLHPGTEYKITVVPMRGTLEGKP 434
Cdd:pfam00041    8 VTDVTSTSLTVSWTPPPDgngPITGYEVEYRPKNSGEPwNEITVPGT---TTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
fn3 pfam00041
Fibronectin type III domain;
533-612 4.45e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.42  E-value: 4.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  533 DSPKNLVTDRVTENMATVSWDP---VQATIDKYMVRYTSADGET--REVPVGKEHSSTILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*
gi 1622827699  608 ESKKT 612
Cdd:pfam00041   81 EGPPS 85
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
369-744 3.38e-09

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 61.17  E-value: 3.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  369 VEWENPSTEVDYYKLRYGPMTGQEVTEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGTLEGKP----ILLNGRTEID 444
Cdd:COG3401    155 ASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsnevSVTTPTTPPS 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  445 SPANLVTDRVTENTATISWDPVQAT-IDKYVVHYTSADNQETREVPVGKEQSSTVlTGLRPGVEYTVHVWAQKGD-RESK 522
Cdd:COG3401    235 APTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFTKVATVTTTSYTD-TGLTNGTTYYYRVTAVDAAgNESA 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  523 KANT-NAPTDI---DSPKNLVTDRVTENMATVSWDPV-QATIDKYMVrYTSADGETREVPVGKEHSST--ILTGLRPGME 595
Cdd:COG3401    314 PSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWTASsDADVTGYNV-YRSTSGGGTYTKIAETVTTTsyTDTGLTPGTT 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  596 YMVHVWAQ-KGDQESKKTDTKAQTDIDSPQNLVTD---WVTENMATVSWDPVQATIDRYVVRYTSAKDGETREVPVGKEQ 671
Cdd:COG3401    393 YYYKVTAVdAAGNESAPSEEVSATTASAASGESLTasvDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTT 472

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622827699  672 NSTVLTGLRPGVEYTVHV--WAQKGAQESKKADTKAQTDID-SPKNLVTDRVTENTATVSWDLVQATIDRYVVRYT 744
Cdd:COG3401    473 TSSTVTATTTDTTTANLSvtTGSLVGGSGASSVTNSVSVIGaSAAAAVGGAPDGTPNVTGASPVTVGASTGDVLIT 548
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 533-614 3.77e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 54.81  E-value: 3.77e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  533 DSPKNLVTDRVTENMATVSWDPVQAT---IDKYMVRYTSADGETREVPVGKEHSST--ILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPGSETsyTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  608 ESKKTDT 614
Cdd:cd00063     82 ESPPSES 88
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 264-332 8.60e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 53.77  E-value: 8.60e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622827699   264 APQGLQLLKSTEESLLVSWEP--SSQVDHYFLNYYPLGKELSGKQIRVPK--EQHSYEILGLLPGTKYIVTLR 332
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPppDDGITGYIVGYRVEYREEGSEWKEVNVtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 264-342 1.32e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 53.27  E-value: 1.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEPS----SQVDHYFLNYYPLGKELSGKQIRVPKEQHSYEILGLLPGTKYIVTLRNVKKDIF 339
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSWTPPeddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82


                   ...
gi 1622827699  340 SSP 342
Cdd:cd00063     83 SPP 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 359-424 1.20e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 1.20e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699   359 VTEETEHSLDVEWENPSTE-VDYYKLRYGPMTGQEVTEVTVPKSSDPKSRYDITGLHPGTEYKITVV 424
Cdd:smart00060    9 VTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 171-197 2.97e-05

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 41.90  E-value: 2.97e-05
                           10        20
                   ....*....|....*....|....*..
gi 1622827699  171 CPGACSGHGRCVDGRCLCHEPYVGADC 197
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
EGF_2 pfam07974
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
 236-259 1.05e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.


Pssm-ID: 400365  Cd Length: 26  Bit Score: 40.41  E-value: 1.05e-04
                           10        20
                   ....*....|....*....|....*.
gi 1622827699  236 DCSGHGFCD--TGECYCEEGFTGLDC 259
Cdd:pfam07974    1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
C_rich_MXAN6577 NF041328
MXAN_6577-like cysteine-rich domain;
170-253 2.09e-04

MXAN_6577-like cysteine-rich domain;


Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 42.82  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  170 ACPGACSGHGRCVDGRCLCHEPYVG------------ADCGypACPENCSGHGECVRGVCQ--CHEDFTseDCSeRRC-- 233
Cdd:NF041328    44 ACGVACGAGQTCVAGACGCGPGTVAcggacvdtasdpAHCG--ACGAACAPGQVCEGGACReaCSEGLT--RCG-GACvd 118

                           90       100
                   ....*....|....*....|....*
gi 1622827699  234 ----PGDCSGHG-FCDTGEcYCEEG 253
Cdd:NF041328   119 latdPLHCGACGvACDPGE-SCRGG 142
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 202-229 1.33e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 37.28  E-value: 1.33e-03
                           10        20
                   ....*....|....*....|....*...
gi 1622827699  202 CPENCSGHGECVRGVCQCHEDFTSEDCS 229
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
 
Name Accession Description Interval E-value
FReD cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...
 977-1188 2.51e-116

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.


Pssm-ID: 238040 [Multi-domain]  Cd Length: 215  Bit Score: 360.02  E-value: 2.51e-116
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  977 PHPSDCSQVQQNSNAASGLYTIYLHGdSSRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTKEFWLGL 1056
Cdd:cd00087      1 PLPRDCSEVLQRGGRTSGVYTIQPPG-SNEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699 1057 DKLHNLTTGTPtrYEVRVDLQT-ANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALSYHNGWKFTTFDRDNDIALSN 1135
Cdd:cd00087     80 EKIHLLTSQGP--YELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGN 157

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699 1136 CALTHHGGWWYKNCHLANPNGRYGETKH----SEGVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:cd00087    158 CAESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRP 214
FBG smart00186
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ...
 978-1188 2.35e-103

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.


Pssm-ID: 214548 [Multi-domain]  Cd Length: 212  Bit Score: 325.00  E-value: 2.35e-103
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   978 HPSDCSQVQQNSNAASGLYTIYLHGdSSRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTKEFWLGLD 1057
Cdd:smart00186    1 LPRDCSDVLQNGGKTSGLYTIYPDG-SSRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  1058 KLHNLTTGTPtrYEVRVDLQ-TANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDA-LSYHNGWKFTTFDRDNDIALSN 1135
Cdd:smart00186   80 NIHLLTSQGK--YELRIDLEdWEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDAsLTYHNGMQFSTYDRDNDKYSGN 157

                           170       180       190       200       210
                    ....*....|....*....|....*....|....*....|....*....|....
gi 1622827699  1136 CALTHHGGWWYKNCHLANPNGRYG-ETKHSEGVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:smart00186  158 CAEEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRP 211
Fibrinogen_C pfam00147
Fibrinogen beta and gamma chains, C-terminal globular domain;
979-1188 6.79e-86

Fibrinogen beta and gamma chains, C-terminal globular domain;


Pssm-ID: 395095 [Multi-domain]  Cd Length: 221  Bit Score: 277.87  E-value: 6.79e-86
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  979 PSDCSQVQQNSNAASGLYTIYLHGDSsRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPTK-EFWLGLD 1057
Cdd:pfam00147    2 GRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSPgEFWLGND 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699 1058 KLHNLTTGTPtrYEVRVDLQTAN-ESAYAIYDFFQVASSKERYKLTVGKYRGTAGDAL-------SYHNGWKFTTFDRDN 1129
Cdd:pfam00147   81 KIHLLTKQGP--YVLRIDLEDWNgETVFALYDSFKVTNENDKYRLHVENYIGDAGDALdtagrsmTYHNGMQFSTWDRDN 158

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622827699 1130 DIALSNCALTHHGGWWYKNCHLANPNGRY--GETKHSE-GVNWEPWKGHEFSIPYVELKIRP 1188
Cdd:pfam00147  159 DSPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRP 220
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
600-980 4.88e-13

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 73.50  E-value: 4.88e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  600 VWAQKGDQESKKTDTKAQTDIDSPQNLVTDWVTENMATVSWDPVQATIDRYVVRYTSAKDGETREVPVGKEQNSTVLTGL 679
Cdd:COG3401     30 GGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNT 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  680 RPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPKNLVTDRVTENTATVSWDLVQATIDRYVVRYTSANGETREVPVGKEQ 759
Cdd:COG3401    110 GLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  760 SSTVLTGLR--PGVEYTVHVWAQKGNQESKKAD----TKAQTEIDSPKNLVTDRVTENMATVSWDPVQAT-IDKYVV-RY 831
Cdd:COG3401    190 TTLVDGGGDiePGTTYYYRVAATDTGGESAPSNevsvTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRVyRS 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  832 TSADGETREVPVGKEhSSTVLTGLRPGMEYMVHVWAQKGD-QESKKADT-KAQTEI---DPPRNLRPSAVTQSGGVLTWT 906
Cdd:COG3401    270 NSGDGPFTKVATVTT-TSYTDTGLTNGTTYYYRVTAVDAAgNESAPSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWT 348

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699  907 PPS-AQIHGYILTY-QFPDGTVKEIQLGREDQRFELQGLEQGATYPVSLVAF-KGGLRSRNVSTTLSTVGARFPHPS 980
Cdd:COG3401    349 ASSdADVTGYNVYRsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVdAAGNESAPSEEVSATTASAASGES 425
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 621-703 1.27e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.83  E-value: 1.27e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  621 DSPQNLVTDWVTENMATVSWDPVQAT---IDRYVVRYTSAKDGETREVPVGK-EQNSTVLTGLRPGVEYTVHVWAQKGAQ 696
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  697 ESKKADT 703
Cdd:cd00063     82 ESPPSES 88
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 444-526 2.29e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.05  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  444 DSPANLVTDRVTENTATISWDPVQAT---IDKYVVHYTSADNQETREVPVGK-EQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  520 ESKKANT 526
Cdd:cd00063     82 ESPPSES 88
fn3 pfam00041
Fibronectin type III domain;
444-522 2.60e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 63.59  E-value: 2.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  444 DSPANLVTDRVTENTATISWDP---VQATIDKYVVHYTSADNQE-TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEpWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ...
gi 1622827699  520 ESK 522
Cdd:pfam00041   81 EGP 83
fn3 pfam00041
Fibronectin type III domain;
264-342 4.58e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 4.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEP----SSQVDHYFLNYYPLGKELSGKQIRVPKEQHSYEILGLLPGTKYIVTLRNVKKDIF 339
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPppdgNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 1622827699  340 SSP 342
Cdd:pfam00041   82 GPP 84
fn3 pfam00041
Fibronectin type III domain;
710-787 1.49e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 61.66  E-value: 1.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  710 DSPKNLVTDRVTENTATVSW---DLVQATIDRYVVRYTSANGET--REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGNQ 784
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ...
gi 1622827699  785 ESK 787
Cdd:pfam00041   81 EGP 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 710-786 1.51e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.48  E-value: 1.51e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   710 DSPKNLVTDRVTENTATVSWDLVQAT-----IDRYVVRYTSANGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGNQ 784
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   785 ES 786
Cdd:smart00060   82 EG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 444-521 1.75e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.09  E-value: 1.75e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   444 DSPANLVTDRVTENTATISWD-PVQATIDKYVVHYT---SADNQETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR 519
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGYRveyREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   520 ES 521
Cdd:smart00060   82 EG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 621-698 2.81e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 60.71  E-value: 2.81e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   621 DSPQNLVTDWVTENMATVSWD-PVQATIDRYVVRYT---SAKDGETREVPVGKEQNSTVLTGLRPGVEYTVHVWAQKGAQ 696
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGYRveyREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   697 ES 698
Cdd:smart00060   82 EG 83
fn3 pfam00041
Fibronectin type III domain;
621-699 4.67e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.12  E-value: 4.67e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  621 DSPQNL-VTDwVTENMATVSWDP---VQATIDRYVVRYTSAKDGE-TREVPVGKEQNSTVLTGLRPGVEYTVHVWAQKGA 695
Cdd:pfam00041    1 SAPSNLtVTD-VTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEpWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                   ....
gi 1622827699  696 QESK 699
Cdd:pfam00041   80 GEGP 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 798-874 5.63e-11

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 59.94  E-value: 5.63e-11
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   798 DSPKNLVTDRVTENMATVSWDPVQAT-----IDKYVVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGDQ 872
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   873 ES 874
Cdd:smart00060   82 EG 83
fn3 pfam00041
Fibronectin type III domain;
798-875 1.19e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 58.97  E-value: 1.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  798 DSPKNLVTDRVTENMATVSWDP---VQATIDKYVVRYTSADGET--REVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGDQ 872
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ...
gi 1622827699  873 ESK 875
Cdd:pfam00041   81 EGP 83
GGGWT_bact NF040941
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ...
 982-1021 2.04e-10

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.


Pssm-ID: 468872 [Multi-domain]  Cd Length: 46  Bit Score: 56.80  E-value: 2.04e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1622827699  982 CSQV-QQNSNAASGLYTIYLHGDSSR-PLQVYCDMDTDGGGW 1021
Cdd:NF040941     2 CWEIlQAGPSAPSGVYWIDPDGMGGLaPFQVYCDMTTDGGGW 43
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 533-609 2.30e-10

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 58.01  E-value: 2.30e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699   533 DSPKNLVTDRVTENMATVSWDPVQAT-----IDKYMVRYTSADGETREVPVGKEHSSTILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 1622827699   608 ES 609
Cdd:smart00060   82 EG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 359-434 2.39e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 58.28  E-value: 2.39e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622827699  359 VTEETEHSLDVEWENPS---TEVDYYKLRYGPMTGQEVTEVTVPKSSDPksRYDITGLHPGTEYKITVVPMRGTLEGKP 434
Cdd:cd00063      9 VTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSET--SYTLTGLKPGTEYEFRVRAVNGGGESPP 85
fn3 pfam00041
Fibronectin type III domain;
359-434 3.01e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.81  E-value: 3.01e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  359 VTEETEHSLDVEWENPST---EVDYYKLRYGPMTGQEV-TEVTVPKSsdpKSRYDITGLHPGTEYKITVVPMRGTLEGKP 434
Cdd:pfam00041    8 VTDVTSTSLTVSWTPPPDgngPITGYEVEYRPKNSGEPwNEITVPGT---TTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 710-791 3.27e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.89  E-value: 3.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  710 DSPKNLVTDRVTENTATVSWDLVQAT---IDRYVVRYTSANGET-REVPVGK-EQSSTVLTGLRPGVEYTVHVWAQKGNQ 784
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDwKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  785 ESKKADT 791
Cdd:cd00063     82 ESPPSES 88
fn3 pfam00041
Fibronectin type III domain;
533-612 4.45e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.42  E-value: 4.45e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  533 DSPKNLVTDRVTENMATVSWDP---VQATIDKYMVRYTSADGET--REVPVGKEHSSTILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....*
gi 1622827699  608 ESKKT 612
Cdd:pfam00041   81 EGPPS 85
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
524-836 6.12e-10

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 63.81  E-value: 6.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  524 ANTNAPTDIDSPKNL--VTDRVTENMATVSWDPVQATIDkYMVRYTSADGETREVPVGKEhSSTILTGLRPGmEYMVHVW 601
Cdd:COG4733    528 PPQWPPVNVTTSESLsvVAQGTAVTTLTVSWDAPAGAVA-YEVEWRRDDGNWVSVPRTSG-TSFEVPGIYAG-DYEVRVR 604

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  602 A-QKGDQESKKTDTKAQT---DIDSPQNLVTDWVTEN--MATVSWD-PVQATIDRYVVRYTSAKDGETREVPVGK-EQNS 673
Cdd:COG4733    605 AiNALGVSSAWAASSETTvtgKTAPPPAPTGLTATGGlgGITLSWSfPVDADTLRTEIRYSTTGDWASATVAQALyPGNT 684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  674 TVLTGLRPGVEYTVHVWA--QKGAQESKKADTKAQTDIDSPKNLVTDRVTENTATVSWDLVQATIDryVVRYTSANGETR 751
Cdd:COG4733    685 YTLAGLKAGQTYYYRARAvdRSGNVSAWWVSGQASADAAGILDAITGQILETELGQELDAIIQNAT--VAEVVAATVTDV 762

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  752 EVPVGKEQS-STVLTGLRPGVEYTVhVWAQKGNQESKKADTKAQTEIDSPKNLVTDrvTENMATVSWDPVQATIDKYVVR 830
Cdd:COG4733    763 TAQIDTAVLfAGVATAAAIGAEARV-AATVAESATAAAATGTAADAAGDASGGVTA--GTSGTTGAGDTAASTTRVAAAV 839


                   ....*.
gi 1622827699  831 YTSADG 836
Cdd:COG4733    840 VLAGVV 845
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 798-879 7.12e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 57.12  E-value: 7.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  798 DSPKNLVTDRVTENMATVSWDPVQAT---IDKYVVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGDQ 872
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPGSETsyTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  873 ESKKADT 879
Cdd:cd00063     82 ESPPSES 88
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
369-744 3.38e-09

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 61.17  E-value: 3.38e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  369 VEWENPSTEVDYYKLRYGPMTGQEVTEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGTLEGKP----ILLNGRTEID 444
Cdd:COG3401    155 ASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsnevSVTTPTTPPS 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  445 SPANLVTDRVTENTATISWDPVQAT-IDKYVVHYTSADNQETREVPVGKEQSSTVlTGLRPGVEYTVHVWAQKGD-RESK 522
Cdd:COG3401    235 APTGLTATADTPGSVTLSWDPVTESdATGYRVYRSNSGDGPFTKVATVTTTSYTD-TGLTNGTTYYYRVTAVDAAgNESA 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  523 KANT-NAPTDI---DSPKNLVTDRVTENMATVSWDPV-QATIDKYMVrYTSADGETREVPVGKEHSST--ILTGLRPGME 595
Cdd:COG3401    314 PSNVvSVTTDLtppAAPSGLTATAVGSSSITLSWTASsDADVTGYNV-YRSTSGGGTYTKIAETVTTTsyTDTGLTPGTT 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  596 YMVHVWAQ-KGDQESKKTDTKAQTDIDSPQNLVTD---WVTENMATVSWDPVQATIDRYVVRYTSAKDGETREVPVGKEQ 671
Cdd:COG3401    393 YYYKVTAVdAAGNESAPSEEVSATTASAASGESLTasvDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTT 472

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622827699  672 NSTVLTGLRPGVEYTVHV--WAQKGAQESKKADTKAQTDID-SPKNLVTDRVTENTATVSWDLVQATIDRYVVRYT 744
Cdd:COG3401    473 TSSTVTATTTDTTTANLSvtTGSLVGGSGASSVTNSVSVIGaSAAAAVGGAPDGTPNVTGASPVTVGASTGDVLIT 548
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 533-614 3.77e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 54.81  E-value: 3.77e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  533 DSPKNLVTDRVTENMATVSWDPVQAT---IDKYMVRYTSADGETREVPVGKEHSST--ILTGLRPGMEYMVHVWAQKGDQ 607
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVTPGSETsyTLTGLKPGTEYEFRVRAVNGGG 81


                   ....*..
gi 1622827699  608 ESKKTDT 614
Cdd:cd00063     82 ESPPSES 88
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 264-332 8.60e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 53.77  E-value: 8.60e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622827699   264 APQGLQLLKSTEESLLVSWEP--SSQVDHYFLNYYPLGKELSGKQIRVPK--EQHSYEILGLLPGTKYIVTLR 332
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPppDDGITGYIVGYRVEYREEGSEWKEVNVtpSSTSYTLTGLKPGTEYEFRVR 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 264-342 1.32e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 53.27  E-value: 1.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEPS----SQVDHYFLNYYPLGKELSGKQIRVPKEQHSYEILGLLPGTKYIVTLRNVKKDIF 339
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSWTPPeddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82


                   ...
gi 1622827699  340 SSP 342
Cdd:cd00063     83 SPP 85
fn3 pfam00041
Fibronectin type III domain;
886-959 2.10e-08

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 52.42  E-value: 2.10e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622827699  886 DPPRNLRPSAVTQSGGVLTWTPP---SAQIHGYILTYQFPDGT--VKEIQLGREDQRFELQGLEQGATYPVSLVAFKGG 959
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 359-424 1.20e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 1.20e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622827699   359 VTEETEHSLDVEWENPSTE-VDYYKLRYGPMTGQEVTEVTVPKSSDPKSRYDITGLHPGTEYKITVV 424
Cdd:smart00060    9 VTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVR 75
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 886-962 2.18e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 2.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  886 DPPRNLRPSAVTQSGGVLTWTPPS---AQIHGYILTYQ-FPDGTVKEIQLGREDQ-RFELQGLEQGATYPVSLVAFKGGL 960
Cdd:cd00063      2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYReKGSGDWKEVEVTPGSEtSYTLTGLKPGTEYEFRVRAVNGGG 81


                   ..
gi 1622827699  961 RS 962
Cdd:cd00063     82 ES 83
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
438-756 1.65e-06

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 52.64  E-value: 1.65e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  438 NGRTEIDSPANLVTDRVT------------ENTATISWDPVQATIDKYVVHYtsADNQETREVPVGKEQSSTVlTGLRPG 505
Cdd:COG4733    521 AGAFDDVPPQWPPVNVTTseslsvvaqgtaVTTLTVSWDAPAGAVAYEVEWR--RDDGNWVSVPRTSGTSFEV-PGIYAG 597

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  506 vEYTVHVWA-QKGDRESKKANT---------NAPTDidsPKNLVTDRVTEnMATVSWD-PVQATIDKYMVRY-TSADGET 573
Cdd:COG4733    598 -DYEVRVRAiNALGVSSAWAASsettvtgktAPPPA---PTGLTATGGLG-GITLSWSfPVDADTLRTEIRYsTTGDWAS 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  574 REVPVGKEHSST-ILTGLRPGMEYmvHVWAQKGDQESKKTD----TKAQTDIDSPQNLVTDWVTEnmaTVSWDPVQATID 648
Cdd:COG4733    673 ATVAQALYPGNTyTLAGLKAGQTY--YYRARAVDRSGNVSAwwvsGQASADAAGILDAITGQILE---TELGQELDAIIQ 747

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  649 RYVVRYTSAKDGETREVPVGKEQN-STVLTGLRPGVEYTVhVWAQKGAQESKKADTKAQTDIDSPKNLVTDR---VTENT 724
Cdd:COG4733    748 NATVAEVVAATVTDVTAQIDTAVLfAGVATAAAIGAEARV-AATVAESATAAAATGTAADAAGDASGGVTAGtsgTTGAG 826

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1622827699  725 ATVSWDLVQATIDRYVVRYTSANGETREVPVG 756
Cdd:COG4733    827 DTAASTTRVAAAVVLAGVVVYGDAIIESGNTG 858
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 886-959 3.69e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.07  E-value: 3.69e-06
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622827699   886 DPPRNLRPSAVTQSGGVLTWTPPSAQ-----IHGYILTYQFPDGTVKEIQLGREDQRFELQGLEQGATYPVSLVAFKGG 959
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 171-197 2.97e-05

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 41.90  E-value: 2.97e-05
                           10        20
                   ....*....|....*....|....*..
gi 1622827699  171 CPGACSGHGRCVDGRCLCHEPYVGADC 197
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
EGF_2 pfam07974
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
 236-259 1.05e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.


Pssm-ID: 400365  Cd Length: 26  Bit Score: 40.41  E-value: 1.05e-04
                           10        20
                   ....*....|....*....|....*.
gi 1622827699  236 DCSGHGFCD--TGECYCEEGFTGLDC 259
Cdd:pfam07974    1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
C_rich_MXAN6577 NF041328
MXAN_6577-like cysteine-rich domain;
170-253 2.09e-04

MXAN_6577-like cysteine-rich domain;


Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 42.82  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  170 ACPGACSGHGRCVDGRCLCHEPYVG------------ADCGypACPENCSGHGECVRGVCQ--CHEDFTseDCSeRRC-- 233
Cdd:NF041328    44 ACGVACGAGQTCVAGACGCGPGTVAcggacvdtasdpAHCG--ACGAACAPGQVCEGGACReaCSEGLT--RCG-GACvd 118

                           90       100
                   ....*....|....*....|....*
gi 1622827699  234 ----PGDCSGHG-FCDTGEcYCEEG 253
Cdd:NF041328   119 latdPLHCGACGvACDPGE-SCRGG 142
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
264-567 7.18e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 43.84  E-value: 7.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEPSSQVDhyfLNYYPL--GKELSGKQIRVPKEQH-SYEILGLLPGTKYIVTLRNVKKDIFS 340
Cdd:COG3401    235 APTGLTATADTPGSVTLSWDPVTESD---ATGYRVyrSNSGDGPFTKVATVTTtSYTDTGLTNGTTYYYRVTAVDAAGNE 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  341 SP--QHLLATTDLAALGTAW---VTEETEHSLDVEWENPSTE-VDYYKLRYGPMTGQEVTEVTvpkSSDPKSRYDITGLH 414
Cdd:COG3401    312 SApsNVVSVTTDLTPPAAPSgltATAVGSSSITLSWTASSDAdVTGYNVYRSTSGGGTYTKIA---ETVTTTSYTDTGLT 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  415 PGTEYKITVV-------------PMRGTLEGKPILLNGRTEIDSPANLVTDRVTENTATISWDPVQATI--DKYVVHYTS 479
Cdd:COG3401    389 PGTTYYYKVTavdaagnesapseEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVlaDGGDTGNAV 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  480 ADNQETREVPVGKEQSSTvltglrpGVEYTVHVWAQKGDRESKKANTNAPTDIDSPKNLVTDRvTENMATVSWDPVQATI 559
Cdd:COG3401    469 PFTTTSSTVTATTTDTTT-------ANLSVTTGSLVGGSGASSVTNSVSVIGASAAAAVGGAP-DGTPNVTGASPVTVGA 540


                   ....*...
gi 1622827699  560 DKYMVRYT 567
Cdd:COG3401    541 STGDVLIT 548
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 202-229 1.33e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 37.28  E-value: 1.33e-03
                           10        20
                   ....*....|....*....|....*...
gi 1622827699  202 CPENCSGHGECVRGVCQCHEDFTSEDCS 229
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
264-492 2.63e-03

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 41.91  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  264 APQGLQLLKSTEESLLVSWEPSSQVD--HYFLnYYPLGKELSGKQIRVPKEQHSYEILGLLPGTKYIVTLRNVKKDIFSS 341
Cdd:COG3401    329 APSGLTATAVGSSSITLSWTASSDADvtGYNV-YRSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGNES 407

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  342 PQHLLATtdlaalGTAWVTEETEHSLDVEWENPSTEVDYYKLRYGPMTGQEVTEVTVPKSSDPKSrYDITGLHPGTEYKI 421
Cdd:COG3401    408 APSEEVS------ATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGN-AVPFTTTSSTVTAT 480

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622827699  422 TVVPMRGTLEGKPILLNGRTEIDSPANLVTDRVTENTATISWDP--VQATIDKYVVHYTSADNQETREVPVGK 492
Cdd:COG3401    481 TTDTTTANLSVTTGSLVGGSGASSVTNSVSVIGASAAAAVGGAPdgTPNVTGASPVTVGASTGDVLITDLVSL 553
EGF_2 pfam07974
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
 174-197 2.95e-03

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.


Pssm-ID: 400365  Cd Length: 26  Bit Score: 36.17  E-value: 2.95e-03
                           10        20
                   ....*....|....*....|....*.
gi 1622827699  174 ACSGHGRCVD--GRCLCHEPYVGADC 197
Cdd:pfam07974    1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
273-665 3.32e-03

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 41.85  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  273 STEESLLVSWEPSSQVDHYFLNYYPLGkelsGKQIRVPK-EQHSYEILGLLPGTkYIVTLR-----NVKKDIFSSPQHLL 346
Cdd:COG4733    549 TAVTTLTVSWDAPAGAVAYEVEWRRDD----GNWVSVPRtSGTSFEVPGIYAGD-YEVRVRainalGVSSAWAASSETTV 623

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  347 A--TTDLAALGTAWVTEETEHsLDVEWENPS-TEVDYYKLRYGpmTGQEVTEVTVPKSSDPKSRYDITGLHPGTEYKITV 423
Cdd:COG4733    624 TgkTAPPPAPTGLTATGGLGG-ITLSWSFPVdADTLRTEIRYS--TTGDWASATVAQALYPGNTYTLAGLKAGQTYYYRA 700

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  424 --VPMRGTLEGKPILLNGRTEIDSPANLVTDRVTE-----------NTATISWDP------VQATIDKYVVHYTSADNQE 484
Cdd:COG4733    701 raVDRSGNVSAWWVSGQASADAAGILDAITGQILEtelgqeldaiiQNATVAEVVaatvtdVTAQIDTAVLFAGVATAAA 780

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  485 TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKANTNAPTDIDSPKNLVTDRVTENMATVSWDPVQATIDKYMV 564
Cdd:COG4733    781 IGAEARVAATVAESATAAAATGTAADAAGDASGGVTAGTSGTTGAGDTAASTTRVAAAVVLAGVVVYGDAIIESGNTGDI 860

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622827699  565 RYTSADGETREVPVGKEHSST-----ILTGLRPGMEYMVHVWAQKGDQESKKTDTKAQTDIDSPQnlvTDWVTENMATVS 639
Cdd:COG4733    861 VATGDIASAAAGAVATTVSGTtaadvSAVADSTAASLTAIVIAATTIIDAIGDGTTREPAGDIGA---SGGAQGFAVTIV 937

                          410       420
                   ....*....|....*....|....*.
gi 1622827699  640 WDPVQATIDRYVVRYTSAKDGETREV 665
Cdd:COG4733    938 GSFDGAGAVATVDAGQSVVDGVGTAV 963
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 233-260 5.06e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 35.74  E-value: 5.06e-03
                           10        20
                   ....*....|....*....|....*...
gi 1622827699  233 CPGDCSGHGFCDTGECYCEEGFTGLDCA 260
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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