|
Name |
Accession |
Description |
Interval |
E-value |
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
13-652 |
0e+00 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 985.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 13 TKVTDWVDPSFDDFLECRDISTITATSLGVNNSSHRRKNGPSTLesskFPARKRGNLSsLEQIYGLENSKESLSENEPWV 92
Cdd:TIGR00602 1 MDVTDWVKPSFDDFLLSSLISTITKWSLSRPTSSHRRKNSPSTD----IHARKRGFLS-LEQDTGLELSSENLDGNEPWV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 93 DKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQggsILLITGPPGCGKTTTIKVLSKEHGIQVQEWINPVLPDFQKD 172
Cdd:TIGR00602 76 EKYKPETQHELAVHKKKIEEVETWLKAQVLENAPKR---ILLITGPSGCGKSTTIKILSKELGIQVQEWSNPTLPDFQKN 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 173 DFREIFNTESSFHMFpyQSQIAVFKEFLLRATkyNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLR-KYVRIGR 251
Cdd:TIGR00602 153 DHKVTLSLESCFSNF--QSQIEVFSEFLLRAT--NKLQMLGDDLMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGR 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 252 CPLIFVISDSLSGDNNQ-RLLFP------KEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLEL 324
Cdd:TIGR00602 229 CPLVFIITESLEGDNNQrRLLFPaetimnKEILEEPRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKVPKKTSVEL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 325 LCQGCSGDIRSAINSLQFSSSKGenNLWPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKIL 404
Cdd:TIGR00602 309 LCQGCSGDIRSAINSLQFSSSKS--GSLPIKKRMSTKSDAHASKSKIKGKHSSNNENQEIQALGGKDVSLFLFRALGKIL 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 405 YCKRASLTELDSPRLPSHLSEYERDTLLVEPEEIVEMSHMPGD-LFNLYLHQNYIDFFMDIDDIVRASEFLSFADILSGD 483
Cdd:TIGR00602 387 YCKRATLNELDSPRLPSHLSELSRDTLMVGPEEVVEMSHMPGDkTFNLYSHQNYNDFFVEFDDEVKASEFLNFADILSGD 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 484 WNTCSLLREYSTSIATRGVIHSNKARGYAHCQGGGSSFRPLHKPQWFLIYKKYRENCLAAKALF--PDFCLPALCLQTQL 561
Cdd:TIGR00602 467 WNTRSLLREYSTSSARRGVMHSNKARGIAHCQGGKSSFRPLHKPQWFLISKKYRENCLAAKALFkvEDFCLPADCLQTQL 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 562 LPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSTEESLGEPTQATAPETW 641
Cdd:TIGR00602 547 LPYLALDTIPMRNDAQISFIDDLGRLPLKRDFRRLKMEALTDREVGMIDPDSGDEETSFGDDPAVESDSDPSQAAGPETW 626
|
650
....*....|.
gi 1622945024 642 SLPLSQNSASE 652
Cdd:TIGR00602 627 SLPDSDNSLSE 637
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
83-270 |
3.07e-90 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 278.77 E-value: 3.07e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 83 ESLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKqggSILLITGPPGCGKTTTIKVLSKEHGIQVQEWI 162
Cdd:pfam03215 1 INDDGGEQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENAKH---RILLISGPSGCGKSTVIKELSKELGPKYREWS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 163 NPVL---PDFQKDDFREIFNTESSFhmfpyQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTL 239
Cdd:pfam03215 78 NPTSfrsPPNQVTDFRGDCIVNSRF-----LSQMESFSEFELKGARYLVMQKRGKNAQGNKKLILIEDLPNVFHIDTRRF 152
|
170 180 190
....*....|....*....|....*....|....
gi 1622945024 240 HEVLRKYVRIGRC-PLIFVIS--DSLSGDNNQRL 270
Cdd:pfam03215 153 QQVIRQWLYSSEPlPLIICITecEILEGDNNQRK 186
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
90-502 |
5.61e-20 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 93.45 E-value: 5.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 90 PWVDKYKPETQHELAVHKKKIEEVETWLKAQvLERQPKQGgsiLLITGPPGCGKTTTIKVLSKEHGIQVQEwINpvlpdf 169
Cdd:PRK04195 3 PWVEKYRPKTLSDVVGNEKAKEQLREWIESW-LKGKPKKA---LLLYGPPGVGKTSLAHALANDYGWEVIE-LN------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 170 qKDDFReifNTEssfhmfpyqsqiaVFKEFLLRATKYNKLqmlgddLRTDKKIILVEDLPNQFYR-DSHTLHEVLrKYVR 248
Cdd:PRK04195 72 -ASDQR---TAD-------------VIERVAGEAATSGSL------FGARRKLILLDEVDGIHGNeDRGGARAIL-ELIK 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 249 IGRCPLIFVISDSLSgdnnqrlLFPKEIQEECSIsnISFNPVAPTIMMKFLNRIVTIEanknggKITVPDKTsLELLCQG 328
Cdd:PRK04195 128 KAKQPIILTANDPYD-------PSLRELRNACLM--IEFKRLSTRSIVPVLKRICRKE------GIECDDEA-LKEIAER 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 329 CSGDIRSAINSLQfSSSKGENNLwprkkgmslksdavlskskrrkkpdrvfENQEVQAIGGKDVSLFLFRALGKIL---Y 405
Cdd:PRK04195 192 SGGDLRSAINDLQ-AIAEGYGKL----------------------------TLEDVKTLGRRDREESIFDALDAVFkarN 242
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 406 CKRA--SLTELDsprlpshlseyerdtllVEPEEIVEmshmpgdlfnlYLHQNYIDFFMDIDDIVRASEFLSFADILSG- 482
Cdd:PRK04195 243 ADQAleASYDVD-----------------EDPDDLIE-----------WIDENIPKEYDDPEDIARAYDALSRADIFLGr 294
|
410 420
....*....|....*....|....*
gi 1622945024 483 -----DWntcSLLReYSTSIATRGV 502
Cdd:PRK04195 295 vkrtqNY---DLWR-YASDLMTAGV 315
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
292-350 |
3.58e-09 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 53.79 E-value: 3.58e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1622945024 292 PTIMMKFLNRIVTIEANKNGGKITVPDKtSLELLCQGCSGDIRSAINSLQFSSSKGENN 350
Cdd:cd18139 3 EEDLEKLLKRALEDKERGGDRKVTIDDE-ALELLAEAADGDARSALNLLELAVLSAEED 60
|
|
| Kti12 |
COG4088 |
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ... |
130-200 |
5.51e-07 |
|
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];
Pssm-ID: 443264 [Multi-domain] Cd Length: 179 Bit Score: 50.11 E-value: 5.51e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622945024 130 GSILLITGPPGCGKTTTIKVLSKEHGiqVQEWINPVLPdfqKDDFREIFNTESsfhmFPYQSQIAVFKEFL 200
Cdd:COG4088 4 PMLLILTGPPGSGKTTFAKALAQRLY--AEGIAVALLH---SDDFRRFLVNES----FPKETYEEVVEDVR 65
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
130-153 |
1.11e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 40.05 E-value: 1.11e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
13-652 |
0e+00 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 985.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 13 TKVTDWVDPSFDDFLECRDISTITATSLGVNNSSHRRKNGPSTLesskFPARKRGNLSsLEQIYGLENSKESLSENEPWV 92
Cdd:TIGR00602 1 MDVTDWVKPSFDDFLLSSLISTITKWSLSRPTSSHRRKNSPSTD----IHARKRGFLS-LEQDTGLELSSENLDGNEPWV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 93 DKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQggsILLITGPPGCGKTTTIKVLSKEHGIQVQEWINPVLPDFQKD 172
Cdd:TIGR00602 76 EKYKPETQHELAVHKKKIEEVETWLKAQVLENAPKR---ILLITGPSGCGKSTTIKILSKELGIQVQEWSNPTLPDFQKN 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 173 DFREIFNTESSFHMFpyQSQIAVFKEFLLRATkyNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLR-KYVRIGR 251
Cdd:TIGR00602 153 DHKVTLSLESCFSNF--QSQIEVFSEFLLRAT--NKLQMLGDDLMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGR 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 252 CPLIFVISDSLSGDNNQ-RLLFP------KEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLEL 324
Cdd:TIGR00602 229 CPLVFIITESLEGDNNQrRLLFPaetimnKEILEEPRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKVPKKTSVEL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 325 LCQGCSGDIRSAINSLQFSSSKGenNLWPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKIL 404
Cdd:TIGR00602 309 LCQGCSGDIRSAINSLQFSSSKS--GSLPIKKRMSTKSDAHASKSKIKGKHSSNNENQEIQALGGKDVSLFLFRALGKIL 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 405 YCKRASLTELDSPRLPSHLSEYERDTLLVEPEEIVEMSHMPGD-LFNLYLHQNYIDFFMDIDDIVRASEFLSFADILSGD 483
Cdd:TIGR00602 387 YCKRATLNELDSPRLPSHLSELSRDTLMVGPEEVVEMSHMPGDkTFNLYSHQNYNDFFVEFDDEVKASEFLNFADILSGD 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 484 WNTCSLLREYSTSIATRGVIHSNKARGYAHCQGGGSSFRPLHKPQWFLIYKKYRENCLAAKALF--PDFCLPALCLQTQL 561
Cdd:TIGR00602 467 WNTRSLLREYSTSSARRGVMHSNKARGIAHCQGGKSSFRPLHKPQWFLISKKYRENCLAAKALFkvEDFCLPADCLQTQL 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 562 LPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSTEESLGEPTQATAPETW 641
Cdd:TIGR00602 547 LPYLALDTIPMRNDAQISFIDDLGRLPLKRDFRRLKMEALTDREVGMIDPDSGDEETSFGDDPAVESDSDPSQAAGPETW 626
|
650
....*....|.
gi 1622945024 642 SLPLSQNSASE 652
Cdd:TIGR00602 627 SLPDSDNSLSE 637
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
83-270 |
3.07e-90 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 278.77 E-value: 3.07e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 83 ESLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKqggSILLITGPPGCGKTTTIKVLSKEHGIQVQEWI 162
Cdd:pfam03215 1 INDDGGEQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENAKH---RILLISGPSGCGKSTVIKELSKELGPKYREWS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 163 NPVL---PDFQKDDFREIFNTESSFhmfpyQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTL 239
Cdd:pfam03215 78 NPTSfrsPPNQVTDFRGDCIVNSRF-----LSQMESFSEFELKGARYLVMQKRGKNAQGNKKLILIEDLPNVFHIDTRRF 152
|
170 180 190
....*....|....*....|....*....|....
gi 1622945024 240 HEVLRKYVRIGRC-PLIFVIS--DSLSGDNNQRL 270
Cdd:pfam03215 153 QQVIRQWLYSSEPlPLIICITecEILEGDNNQRK 186
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
90-502 |
5.61e-20 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 93.45 E-value: 5.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 90 PWVDKYKPETQHELAVHKKKIEEVETWLKAQvLERQPKQGgsiLLITGPPGCGKTTTIKVLSKEHGIQVQEwINpvlpdf 169
Cdd:PRK04195 3 PWVEKYRPKTLSDVVGNEKAKEQLREWIESW-LKGKPKKA---LLLYGPPGVGKTSLAHALANDYGWEVIE-LN------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 170 qKDDFReifNTEssfhmfpyqsqiaVFKEFLLRATKYNKLqmlgddLRTDKKIILVEDLPNQFYR-DSHTLHEVLrKYVR 248
Cdd:PRK04195 72 -ASDQR---TAD-------------VIERVAGEAATSGSL------FGARRKLILLDEVDGIHGNeDRGGARAIL-ELIK 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 249 IGRCPLIFVISDSLSgdnnqrlLFPKEIQEECSIsnISFNPVAPTIMMKFLNRIVTIEanknggKITVPDKTsLELLCQG 328
Cdd:PRK04195 128 KAKQPIILTANDPYD-------PSLRELRNACLM--IEFKRLSTRSIVPVLKRICRKE------GIECDDEA-LKEIAER 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 329 CSGDIRSAINSLQfSSSKGENNLwprkkgmslksdavlskskrrkkpdrvfENQEVQAIGGKDVSLFLFRALGKIL---Y 405
Cdd:PRK04195 192 SGGDLRSAINDLQ-AIAEGYGKL----------------------------TLEDVKTLGRRDREESIFDALDAVFkarN 242
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 406 CKRA--SLTELDsprlpshlseyerdtllVEPEEIVEmshmpgdlfnlYLHQNYIDFFMDIDDIVRASEFLSFADILSG- 482
Cdd:PRK04195 243 ADQAleASYDVD-----------------EDPDDLIE-----------WIDENIPKEYDDPEDIARAYDALSRADIFLGr 294
|
410 420
....*....|....*....|....*
gi 1622945024 483 -----DWntcSLLReYSTSIATRGV 502
Cdd:PRK04195 295 vkrtqNY---DLWR-YASDLMTAGV 315
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
292-350 |
3.58e-09 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 53.79 E-value: 3.58e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1622945024 292 PTIMMKFLNRIVTIEANKNGGKITVPDKtSLELLCQGCSGDIRSAINSLQFSSSKGENN 350
Cdd:cd18139 3 EEDLEKLLKRALEDKERGGDRKVTIDDE-ALELLAEAADGDARSALNLLELAVLSAEED 60
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
91-349 |
3.88e-07 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 52.68 E-value: 3.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 91 WVDKYKPETQHELAVHkkkiEEVETWLKAQVLERQPKQggsiLLITGPPGCGKTTTIKVLSKE-HGiqvQEWINPvLPDF 169
Cdd:PRK12402 5 WTEKYRPALLEDILGQ----DEVVERLSRAVDSPNLPH----LLVQGPPGSGKTAAVRALARElYG---DPWENN-FTEF 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 170 QKDDF-----REIFNTEsSFHMF------PYQSQIAVFKEFLLRATKYNKLQmlgddlrTDKKIILV---EDLPNQFyrd 235
Cdd:PRK12402 73 NVADFfdqgkKYLVEDP-RFAHFlgtdkrIRSSKIDNFKHVLKEYASYRPLS-------ADYKTILLdnaEALREDA--- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 236 SHTLHEVLRKYVRIGRcpliFVISDSlsgdNNQRLLFPkeIQEECsiSNISFNPVAPTIMMKFLNRIVTIEanknggKIT 315
Cdd:PRK12402 142 QQALRRIMEQYSRTCR----FIIATR----QPSKLIPP--IRSRC--LPLFFRAPTDDELVDVLESIAEAE------GVD 203
|
250 260 270
....*....|....*....|....*....|....
gi 1622945024 316 VPDKtSLELLCQGCSGDIRSAINSLQFSSSKGEN 349
Cdd:PRK12402 204 YDDD-GLELIAYYAGGDLRKAILTLQTAALAAGE 236
|
|
| Kti12 |
COG4088 |
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ... |
130-200 |
5.51e-07 |
|
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];
Pssm-ID: 443264 [Multi-domain] Cd Length: 179 Bit Score: 50.11 E-value: 5.51e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622945024 130 GSILLITGPPGCGKTTTIKVLSKEHGiqVQEWINPVLPdfqKDDFREIFNTESsfhmFPYQSQIAVFKEFL 200
Cdd:COG4088 4 PMLLILTGPPGSGKTTFAKALAQRLY--AEGIAVALLH---SDDFRRFLVNES----FPKETYEEVVEDVR 65
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
87-349 |
1.05e-05 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 47.95 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 87 ENEPWVDKYKPETQHELAVHkkkiEEVETWLKAQVLERQ-PKqggsiLLITGPPGCGKTTTIKVLSKEhgiqvqewinpV 165
Cdd:PRK00440 3 MEEIWVEKYRPRTLDEIVGQ----EEIVERLKSYVKEKNmPH-----LLFAGPPGTGKTTAALALARE-----------L 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 166 LPDFQKDDFREIfNTESsfhmfpyQSQIAV----FKEFLlratkynKLQMLGDdlrTDKKIILVeDLPNQFYRDS-HTLH 240
Cdd:PRK00440 63 YGEDWRENFLEL-NASD-------ERGIDVirnkIKEFA-------RTAPVGG---APFKIIFL-DEADNLTSDAqQALR 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 241 EVLRKYVRIGRcpliFVISDSLSgdnnQRLLFPkeIQEECSIsnISFNPVAPTIMMKFLNRIVTIEanknggKITVPDKt 320
Cdd:PRK00440 124 RTMEMYSQNTR----FILSCNYS----SKIIDP--IQSRCAV--FRFSPLKKEAVAERLRYIAENE------GIEITDD- 184
|
250 260
....*....|....*....|....*....
gi 1622945024 321 SLELLCQGCSGDIRSAINSLQFSSSKGEN 349
Cdd:PRK00440 185 ALEAIYYVSEGDMRKAINALQAAAATGKE 213
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
295-349 |
1.26e-05 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 43.29 E-value: 1.26e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1622945024 295 MMKFLNRIVTIEanknggKITVPDKtSLELLCQGCSGDIRSAINSLQFSSSKGEN 349
Cdd:cd18140 6 IVKRLREICKKE------GVKIDEE-ALEAIAEKSEGDMRKAINDLQAAAAGGGV 53
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
107-153 |
1.33e-05 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 47.98 E-value: 1.33e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1622945024 107 KKKIEEVETWLKAQVLERQ---PKQGGSILLiTGPPGCGKTTTIKVLSKE 153
Cdd:COG0464 166 KEELRELVALPLKRPELREeygLPPPRGLLL-YGPPGTGKTLLARALAGE 214
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
90-153 |
5.98e-05 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 45.49 E-value: 5.98e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945024 90 PWVDKYKPETQHELAVHKKKIEevetwlKAQVLERqpkqGGSI--LLITGPPGCGKTTTIKVLSKE 153
Cdd:PLN03025 2 PWVEKYRPTKLDDIVGNEDAVS------RLQVIAR----DGNMpnLILSGPPGTGKTTSILALAHE 57
|
|
| AAA_18 |
pfam13238 |
AAA domain; |
134-235 |
6.58e-05 |
|
AAA domain;
Pssm-ID: 433052 [Multi-domain] Cd Length: 128 Bit Score: 43.19 E-value: 6.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 134 LITGPPGCGKTTTIKVLSKEHGIQvqewinpvlpDFQKDDFREIFNTESSFHmfpyqsQIAVFKEFLLRATKYNKLQMLG 213
Cdd:pfam13238 2 LITGTPGVGKTTLAKELSKRLGFG----------DNVRDLALENGLVLGDDP------ETRESKRLDEDKLDRLLDLLEE 65
|
90 100
....*....|....*....|..
gi 1622945024 214 DDLRTDKKIILVEDLPNQFYRD 235
Cdd:pfam13238 66 NAALEEGGNLIIDGHLAELEPE 87
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
103-158 |
1.29e-04 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 43.04 E-value: 1.29e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945024 103 LAVHKKKIEEVETWLKAQVLERQPKQGgsILLItGPPGCGKTTTIKVLSKEHGIQV 158
Cdd:cd19481 2 KASLREAVEAPRRGSRLRRYGLGLPKG--ILLY-GPPGTGKTLLAKALAGELGLPL 54
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
117-187 |
1.84e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 42.13 E-value: 1.84e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945024 117 LKAQVLERQPKQGGSILLITGPPGCGKTTTIKVLSKEhgiqVQEWINPVL----PDF-QKDDFREIFNTESSFHMF 187
Cdd:cd00009 6 AIEALREALELPPPKNLLLYGPPGTGKTTLARAIANE----LFRPGAPFLylnaSDLlEGLVVAELFGHFLVRLLF 77
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
133-158 |
5.20e-04 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 40.65 E-value: 5.20e-04
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
130-153 |
1.11e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 40.05 E-value: 1.11e-03
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
129-158 |
1.95e-03 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 39.46 E-value: 1.95e-03
10 20 30
....*....|....*....|....*....|...
gi 1622945024 129 GGSILLITGPPGCGKTTTIKVL---SKEHGIQV 158
Cdd:cd17933 11 RNRVSVLTGGAGTGKTTTLKALlaaLEAEGKRV 43
|
|
| dNK |
pfam01712 |
Deoxynucleoside kinase; This family consists of various deoxynucleoside kinases cytidine EC:2. ... |
135-193 |
2.41e-03 |
|
Deoxynucleoside kinase; This family consists of various deoxynucleoside kinases cytidine EC:2.7.1.74, guanosine EC:2.7.1.113, adenosine EC:2.7.1.76 and thymidine kinase EC:2.7.1.21 (which also phosphorylates deoxyuridine and deoxycytosine.) These enzymes catalyze the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside. Using ATP and yielding ADP in the process.
Pssm-ID: 396326 Cd Length: 201 Bit Score: 39.61 E-value: 2.41e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945024 135 ITGPPGCGKTTTIKVLSKEHGIQ-----VQEWINPVLPDFQKDDFREIF--NTESSFHMFPYQSQI 193
Cdd:pfam01712 3 IEGNIGAGKSTLTKILSKRLGFKvfeepVDRWTNPYLDKFYKDPSRWSFalQTYFLNSRFKQQLEA 68
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
107-153 |
2.59e-03 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 40.25 E-value: 2.59e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1622945024 107 KKKIEEV-ETWLKAQVLER---QPKQGgsiLLITGPPGCGKTTTIKVLSKE 153
Cdd:COG1223 11 KKKLKLIiKELRRRENLRKfglWPPRK---ILFYGPPGTGKTMLAEALAGE 58
|
|
| PRK13768 |
PRK13768 |
GTPase; Provisional |
131-263 |
2.79e-03 |
|
GTPase; Provisional
Pssm-ID: 237498 [Multi-domain] Cd Length: 253 Bit Score: 39.85 E-value: 2.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 131 SILLITGPPGCGKTTTIKVLSK---EHGIQVQ--------EWInPVLPDFqkdDFREIFNTES---SFHMFPYQSQIAVF 196
Cdd:PRK13768 3 YIVFFLGTAGSGKTTLTKALSDwleEQGYDVAivnldpavEYL-PYTPDF---DVRDYVTAREimkKYGLGPNGALIASV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622945024 197 kEFLLraTKYNKLQMLGDDLRTDkkIILVeDLPNQ---F-YRDSHTlhEVLRKYVRIGRCPLIFVISDSLS 263
Cdd:PRK13768 79 -DLLL--TKADEIKEEIESLDAD--YVLV-DTPGQmelFaFRESGR--KLVERLSGSSKSVVVFLIDAVLA 141
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
119-260 |
3.71e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 38.64 E-value: 3.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 119 AQVLERQPKQGGSILLITGPPGCGKTTTIKVLSKEHGIQvqewinpvlpdfqkddfREIFNTESSFHMFPYQSQIAVFKE 198
Cdd:pfam13191 13 LDALDRVRSGRPPSVLLTGEAGTGKTTLLRELLRALERD-----------------GGYFLRGKCDENLPYSPLLEALTR 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622945024 199 FLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRC---PLIFVISD 260
Cdd:pfam13191 76 EGLLRQLLDELESSLLEAWRAALLEALAPVPELPGDLAERLLDLLLRLLDLLARgerPLVLVLDD 140
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
61-205 |
3.96e-03 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 40.14 E-value: 3.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 61 FPARKRGNLSSLEQIYGLENSKESLSENEPWVDKYkpetqhelaVHKKKIEEVETWLKAqvLERQPkqggsILLITGPPG 140
Cdd:COG1401 168 APEDLSADALAAELSAAEELYSEDLESEDDYLKDL---------LREKFEETLEAFLAA--LKTKK-----NVILAGPPG 231
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622945024 141 CGKTTTIKVLSKEHGIQVQEWIN--PVLPDFQKDDFRE-IFNTESSFHmfpYQSQIAVFKEFLLRATK 205
Cdd:COG1401 232 TGKTYLARRLAEALGGEDNGRIEfvQFHPSWSYEDFLLgYRPSLDEGK---YEPTPGIFLRFCLKAEK 296
|
|
| ExeA |
COG3267 |
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ... |
128-150 |
4.17e-03 |
|
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442498 [Multi-domain] Cd Length: 261 Bit Score: 39.39 E-value: 4.17e-03
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
31-153 |
4.82e-03 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 39.60 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945024 31 DISTITATSLGVNNSSHRRKNGPSTLESSKFPARKRGNLSSLEQIYGLENSKESLSENEPWVDKYKPE-TQHELAVHKKK 109
Cdd:COG1222 7 IDENIKALLALIDALQERLGVELALLLQPVKALELLEEAPALLLNDANLTQKRLGTPRGTAVPAESPDvTFDDIGGLDEQ 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1622945024 110 IEE----VETWLK-AQVLER---QPKQGgsILLiTGPPGCGKTTTIKVLSKE 153
Cdd:COG1222 87 IEEireaVELPLKnPELFRKygiEPPKG--VLL-YGPPGTGKTLLAKAVAGE 135
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
91-158 |
6.52e-03 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 39.20 E-value: 6.52e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622945024 91 WVDKYKPETQHE--LAVHKKKIeevetwLKAQVlerqpKQGG--SILLITGPPGCGKTTTIKVLSKEHGIQV 158
Cdd:PHA02544 11 WEQKYRPSTIDEciLPAADKET------FKSIV-----KKGRipNMLLHSPSPGTGKTTVAKALCNEVGAEV 71
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
130-151 |
7.13e-03 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 37.61 E-value: 7.13e-03
|
| AAA_28 |
pfam13521 |
AAA domain; |
135-158 |
9.18e-03 |
|
AAA domain;
Pssm-ID: 433278 [Multi-domain] Cd Length: 164 Bit Score: 37.63 E-value: 9.18e-03
|
| Fap7 |
COG1936 |
Broad-specificity NMP kinase [Nucleotide transport and metabolism]; |
132-158 |
9.33e-03 |
|
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
Pssm-ID: 441539 [Multi-domain] Cd Length: 173 Bit Score: 37.49 E-value: 9.33e-03
10 20
....*....|....*....|....*..
gi 1622945024 132 ILLITGPPGCGKTTTIKVLSKEHGIQV 158
Cdd:COG1936 2 RIAITGTPGTGKTTVAKLLAERLGLEV 28
|
|
| |
