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Conserved domains on  [gi|1622938339|ref|XP_028704071|]
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cilia- and flagella-associated protein 99 [Macaca mulatta]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 310-614 2.05e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 2.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 310 QRQVEQELQRVDklvdgagdfSEFLEWQKKMQAKDREEQLAASECRRLQGKLSHEEAilarqsLMQENKQRVEQQKEQMA 389
Cdd:COG1196   262 LAELEAELEELR---------LELEELELELEEAQAEEYELLAELARLEQDIARLEE------RRRELEERLEELEEELA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 390 KLMLQHAETRLREDRSRKQLVEqvIEGQKNVKAAQTKLTKGRRQTVQEVIEESRGLLRRRAQAAQEEQRRRCELISQLRA 469
Cdd:COG1196   327 ELEEELEELEEELEELEEELEE--AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 470 LETQptrkgklvdltqtpgyglegEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNTVEQISLCRAAMGR 549
Cdd:COG1196   405 LEEA--------------------EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622938339 550 SAALRWEEKKALAAapeapsqderVQQLRRRISERAAERSRQAALLHVSAPRAAGPKPRAQLEAQ 614
Cdd:COG1196   465 LAELLEEAALLEAA----------LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 310-614 2.05e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 2.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 310 QRQVEQELQRVDklvdgagdfSEFLEWQKKMQAKDREEQLAASECRRLQGKLSHEEAilarqsLMQENKQRVEQQKEQMA 389
Cdd:COG1196   262 LAELEAELEELR---------LELEELELELEEAQAEEYELLAELARLEQDIARLEE------RRRELEERLEELEEELA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 390 KLMLQHAETRLREDRSRKQLVEqvIEGQKNVKAAQTKLTKGRRQTVQEVIEESRGLLRRRAQAAQEEQRRRCELISQLRA 469
Cdd:COG1196   327 ELEEELEELEEELEELEEELEE--AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 470 LETQptrkgklvdltqtpgyglegEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNTVEQISLCRAAMGR 549
Cdd:COG1196   405 LEEA--------------------EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622938339 550 SAALRWEEKKALAAapeapsqderVQQLRRRISERAAERSRQAALLHVSAPRAAGPKPRAQLEAQ 614
Cdd:COG1196   465 LAELLEEAALLEAA----------LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
PTZ00121 PTZ00121
MAEBL; Provisional
 303-591 5.43e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 5.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  303 LREGALYQRQVEQELQRVDKLVDGAGDFSEFLEWQKKMQAKDREEQLAASECRRLQGKLSHEEAILARQSLMQENKQRVE 382
Cdd:PTZ00121  1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  383 QQK--EQMAKLMLQHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLTKGRRQTVQEV--IEESRGLLRRRAQAAQEEQR 458
Cdd:PTZ00121  1568 EAKkaEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKK 1647

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  459 RRCELisqLRALETQPTRKGKLVDLTQTPGYGLEgEMSIVELRERLAllKENQRRKEEEKRD-----QIIQGKRTKSQEL 533
Cdd:PTZ00121  1648 KAEEL---KKAEEENKIKAAEEAKKAEEDKKKAE-EAKKAEEDEKKA--AEALKKEAEEAKKaeelkKKEAEEKKKAEEL 1721

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622938339  534 QNTVEQISLCRAAMGRSAAlrwEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQ 591
Cdd:PTZ00121  1722 KKAEEENKIKAEEAKKEAE---EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 361-594 4.49e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 361 LSHEEAILARQSlmQENKQRVEQQKeqmaklMLQHAETRLREDRSRKQLVEQ------VIEGQKNVKAAQTKLTKGRRQT 434
Cdd:pfam17380 278 VQHQKAVSERQQ--QEKFEKMEQER------LRQEKEEKAREVERRRKLEEAekarqaEMDRQAAIYAEQERMAMERERE 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 435 VQEVIEESRGllRRRAQAAQEEQRRRCELISQLRALETQPTRKGKLV--DLTQTPGYGLEGEMSIVELRERLALLKENQR 512
Cdd:pfam17380 350 LERIRQEERK--RELERIRQEEIAMEISRMRELERLQMERQQKNERVrqELEAARKVKILEEERQRKIQQQKVEMEQIRA 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 513 RKEEEKRDQIIQGKRTKSQELQNTVEQISLCRAAMGRSAALRWEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQA 592
Cdd:pfam17380 428 EQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507


                  ..
gi 1622938339 593 AL 594
Cdd:pfam17380 508 MI 509
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 332-597 4.80e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 4.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  332 EFLEWQKKMQAKDREEQLAASECRRLQGKL-----SHEEAILARQSLMQE-------------NKQRVEQQKEqmaklml 393
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELqeleeKLEELRLEVSELEEEieelqkelyalanEISRLEQQKQ------- 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  394 QHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLTKgrrqtVQEVIEESRGLLRRRAQAAQEEQRRRCELISQLRALETQ 473
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAE-----LEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  474 PTRKGKLVDLTQTPGYGLEGEmsIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNTVEQIslcraamgrsAAL 553
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNE--IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL----------EEE 448

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1622938339  554 RWEEKKALAAAPEA-PSQDERVQQLRRRISERAAERSRQAALLHV 597
Cdd:TIGR02168  449 LEELQEELERLEEAlEELREELEEAEQALDAAERELAQLQARLDS 493
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 310-614 2.05e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 2.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 310 QRQVEQELQRVDklvdgagdfSEFLEWQKKMQAKDREEQLAASECRRLQGKLSHEEAilarqsLMQENKQRVEQQKEQMA 389
Cdd:COG1196   262 LAELEAELEELR---------LELEELELELEEAQAEEYELLAELARLEQDIARLEE------RRRELEERLEELEEELA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 390 KLMLQHAETRLREDRSRKQLVEqvIEGQKNVKAAQTKLTKGRRQTVQEVIEESRGLLRRRAQAAQEEQRRRCELISQLRA 469
Cdd:COG1196   327 ELEEELEELEEELEELEEELEE--AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 470 LETQptrkgklvdltqtpgyglegEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNTVEQISLCRAAMGR 549
Cdd:COG1196   405 LEEA--------------------EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622938339 550 SAALRWEEKKALAAapeapsqderVQQLRRRISERAAERSRQAALLHVSAPRAAGPKPRAQLEAQ 614
Cdd:COG1196   465 LAELLEEAALLEAA----------LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
PTZ00121 PTZ00121
MAEBL; Provisional
 303-591 5.43e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 5.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  303 LREGALYQRQVEQELQRVDKLVDGAGDFSEFLEWQKKMQAKDREEQLAASECRRLQGKLSHEEAILARQSLMQENKQRVE 382
Cdd:PTZ00121  1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  383 QQK--EQMAKLMLQHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLTKGRRQTVQEV--IEESRGLLRRRAQAAQEEQR 458
Cdd:PTZ00121  1568 EAKkaEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKK 1647

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  459 RRCELisqLRALETQPTRKGKLVDLTQTPGYGLEgEMSIVELRERLAllKENQRRKEEEKRD-----QIIQGKRTKSQEL 533
Cdd:PTZ00121  1648 KAEEL---KKAEEENKIKAAEEAKKAEEDKKKAE-EAKKAEEDEKKA--AEALKKEAEEAKKaeelkKKEAEEKKKAEEL 1721

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622938339  534 QNTVEQISLCRAAMGRSAAlrwEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQ 591
Cdd:PTZ00121  1722 KKAEEENKIKAEEAKKEAE---EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 366-606 2.17e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 2.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 366 AILARQSLMQENKQRVEQQKEQMAKLMLQHAETRLREDRSRKQLveQVIEGQKNVKAAQTKLTKGRRQTVQEVIEEsrgL 445
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL--AALERRIAALARRIRALEQELAALEAELAE---L 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 446 LRRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQTPGYGLEGEMSIV-----ELRERLALLKENQRRKEEEKRD 520
Cdd:COG4942    89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLkylapARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 521 QIIQGKRTKSQELQNTVEQISLCRAAMGRSAALRWEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQAALLHVSAP 600
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                  ....*.
gi 1622938339 601 RAAGPK 606
Cdd:COG4942   249 AALKGK 254
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 346-632 3.48e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  346 EEQLAASECRRLQGKLSHEEAILARQSLMQENKQRVEQQKEQMAKLMLQHAETRlredrsrkqlvEQVIEGQKNVKAAQT 425
Cdd:COG3096    328 DYQAASDHLNLVQTALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAE-----------ARLEAAEEEVDSLKS 396

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  426 KLTKgrrqtVQEVIEE--SRGLLRRRAQAAQEEQRRRCEL--ISQLRALETQPTRKGKLVDLTQtpgyglegemSIVELR 501
Cdd:COG3096    397 QLAD-----YQQALDVqqTRAIQYQQAVQALEKARALCGLpdLTPENAEDYLAAFRAKEQQATE----------EVLELE 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  502 ERLALLKENQRRKEeekrdqiiqgkrtKSQELqntVEQISlcrAAMGRSAAlrWEE-KKALAAAPEAPSQDERVQQLRRR 580
Cdd:COG3096    462 QKLSVADAARRQFE-------------KAYEL---VCKIA---GEVERSQA--WQTaRELLRRYRSQQALAQRLQQLRAQ 520

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622938339  581 ISE-RAAERSRQAA--LLHVSAPRAAGPKP--------RAQLEAQ---HWLELERSRERRLQALQQ 632
Cdd:COG3096    521 LAElEQRLRQQQNAerLLEEFCQRIGQQLDaaeeleelLAELEAQleeLEEQAAEAVEQRSELRQQ 586
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 361-594 4.49e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 361 LSHEEAILARQSlmQENKQRVEQQKeqmaklMLQHAETRLREDRSRKQLVEQ------VIEGQKNVKAAQTKLTKGRRQT 434
Cdd:pfam17380 278 VQHQKAVSERQQ--QEKFEKMEQER------LRQEKEEKAREVERRRKLEEAekarqaEMDRQAAIYAEQERMAMERERE 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 435 VQEVIEESRGllRRRAQAAQEEQRRRCELISQLRALETQPTRKGKLV--DLTQTPGYGLEGEMSIVELRERLALLKENQR 512
Cdd:pfam17380 350 LERIRQEERK--RELERIRQEEIAMEISRMRELERLQMERQQKNERVrqELEAARKVKILEEERQRKIQQQKVEMEQIRA 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 513 RKEEEKRDQIIQGKRTKSQELQNTVEQISLCRAAMGRSAALRWEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQA 592
Cdd:pfam17380 428 EQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507


                  ..
gi 1622938339 593 AL 594
Cdd:pfam17380 508 MI 509
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 332-597 4.80e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 4.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  332 EFLEWQKKMQAKDREEQLAASECRRLQGKL-----SHEEAILARQSLMQE-------------NKQRVEQQKEqmaklml 393
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELqeleeKLEELRLEVSELEEEieelqkelyalanEISRLEQQKQ------- 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  394 QHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLTKgrrqtVQEVIEESRGLLRRRAQAAQEEQRRRCELISQLRALETQ 473
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAE-----LEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  474 PTRKGKLVDLTQTPGYGLEGEmsIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNTVEQIslcraamgrsAAL 553
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNE--IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL----------EEE 448

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1622938339  554 RWEEKKALAAAPEA-PSQDERVQQLRRRISERAAERSRQAALLHV 597
Cdd:TIGR02168  449 LEELQEELERLEEAlEELREELEEAEQALDAAERELAQLQARLDS 493
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
406-594 6.05e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 6.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  406 RKQLVEQVIEGQKNVKAAQTKLTKGRRQtvQEVIEESRGLLRRRAQAAQEEQRRRcELISQLRALETQptrkgkLVDLTQ 485
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEALEAE--LDALQERREALQRLAEYSWDEIDVA-SAEREIAELEAE------LERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  486 TPGyglegemSIVELRERLALLKENQRRKEEEkRDQIIQGKRTKSQELQNTVEQISLCRAAMGRSAAL-RWEEKKALAAA 564
Cdd:COG4913    683 SSD-------DLAALEEQLEELEAELEELEEE-LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLaRLELRALLEER 754

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1622938339  565 PEAPSQDERVQQLRRRI-SERAAERSRQAAL 594
Cdd:COG4913    755 FAAALGDAVERELRENLeERIDALRARLNRA 785
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 312-434 9.55e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.52  E-value: 9.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  312 QVEQELQRVDKLVDGAGDFSEFLEWQ-----KKMQAKDREEQLAAS-------ECRRLQG-----KLSHEEAILARQSLM 374
Cdd:pfam12128  601 ELRERLDKAEEALQSAREKQAAAEEQlvqanGELEKASREETFARTalknarlDLRRLFDekqseKDKKNKALAERKDSA 680

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622938339  375 QENKQRVEQQKEQMA---KLMLQHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLTKGRRQT 434
Cdd:pfam12128  681 NERLNSLEAQLKQLDkkhQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRS 743
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
344-594 1.17e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 344 DREEQLAASECRRLQGKLSHEEAilarqslmqenKQRVEQQKEqmaklmLQHAETRLREDRSRKQLVEQVIEGQKNVKAA 423
Cdd:PRK02224  472 EDRERVEELEAELEDLEEEVEEV-----------EERLERAED------LVEAEDRIERLEERREDLEELIAERRETIEE 534

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 424 QTKLTKGRRQTVQEVIEESRGL------LRRRAQAAQEE----QRRRCELISQLRALETQPTRKGKLVDLTQTPGYGLEG 493
Cdd:PRK02224  535 KRERAEELRERAAELEAEAEEKreaaaeAEEEAEEAREEvaelNSKLAELKERIESLERIRTLLAAIADAEDEIERLREK 614

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 494 EMSIVEL----RERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNTVEQISlcraamGRSAALRWEEKKALAAAPEAPS 569
Cdd:PRK02224  615 REALAELnderRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVE------EKLDELREERDDLQAEIGAVEN 688

                         250       260
                  ....*....|....*....|....*
gi 1622938339 570 QDERVQQLRRRISERAAERSRQAAL 594
Cdd:PRK02224  689 ELEELEELRERREALENRVEALEAL 713
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 303-631 1.30e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.88  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  303 LREGALYQRQVEQELQRVDKLVDGAGDFSEFLEWQKKMQAKDREEQLAASECRRLQGKLSHEEAILARQSLMQENKQRVE 382
Cdd:TIGR00618  351 HSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAK 430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  383 QQKEQMAKLMLQHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLtkGRRQTVQEVIEESRGLLRRRAQAAQEEQRRRCE 462
Cdd:TIGR00618  431 KQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQL--QTKEQIHLQETRKKAVVLARLLELQEEPCPLCG 508

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  463 LISQLRALETQPTRKGKLVDLTQTPGYGL-EGEMSIVELRERL-ALLKENQRRKEEEKR----DQIIQGKRTKSQELQNT 536
Cdd:TIGR00618  509 SCIHPNPARQDIDNPGPLTRRMQRGEQTYaQLETSEEDVYHQLtSERKQRASLKEQMQEiqqsFSILTQCDNRSKEDIPN 588

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  537 VEQIsLCRAAMGRSAALRWEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRAAGPKPR----AQLE 612
Cdd:TIGR00618  589 LQNI-TVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERvrehALSI 667

                          330
                   ....*....|....*....
gi 1622938339  613 AQHWLELERSRERRLQALQ 631
Cdd:TIGR00618  668 RVLPKELLASRQLALQKMQ 686
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 331-640 2.08e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 331 SEFLEWQKKMQAKDREEQLAASECRRLQGKLshEEAilarQSLMQENKQRVEQQKEQMAKLMLQHAETRLREDRSRKQLV 410
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAEL--EEL----NEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 411 EQVIEGQKNvkaaqtkltkGRRQTVQEVIEESRGL--LRRRAQAAQEEQRRRCELISQLRALETQPTRKGKlvdltqtpg 488
Cdd:COG3883    90 ERARALYRS----------GGSVSYLDVLLGSESFsdFLDRLSALSKIADADADLLEELKADKAELEAKKA--------- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 489 yglegemsivELRERLALLKENQRRKEEEKRDqiIQGKRTKSQELQNTVEQISlcRAAMGRSAALRWEEKKALAAAPEAP 568
Cdd:COG3883   151 ----------ELEAKLAELEALKAELEAAKAE--LEAQQAEQEALLAQLSAEE--AAAEAQLAELEAELAAAEAAAAAAA 216

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622938339 569 SQDERVQQLRRRISERAAERSRQAALLHVSAPRAAGPKPRAQLEAQHWLELERSRERRLQALQQGGSGPGPA 640
Cdd:COG3883   217 AAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGG 288
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
379-635 2.90e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 2.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  379 QRVEQQKEQMAKL--MLQHAEtRLREDRSRKQLVEQVIEGQkNVKAAQTKLtkgrrQTVQEVIEESRGLLRRRAQAAQEE 456
Cdd:COG4913    242 EALEDAREQIELLepIRELAE-RYAAARERLAELEYLRAAL-RLWFAQRRL-----ELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  457 QRRRCELISQLRALETQptrkgklvdLTQTPGyglegemsivelrERLALLKENQRRKEEEKRDQiiqgkRTKSQELQNT 536
Cdd:COG4913    315 EARLDALREELDELEAQ---------IRGNGG-------------DRLEQLEREIERLERELEER-----ERRRARLEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  537 VEQISLcraamgrsaALRWEEKKALAAAPEAPSQDERVQQLRRRISERAAERSRQaallhvsapraagpkpRAQLEAQHw 616
Cdd:COG4913    368 LAALGL---------PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA----------------LRDLRREL- 421

                          250
                   ....*....|....*....
gi 1622938339  617 leleRSRERRLQALQQGGS 635
Cdd:COG4913    422 ----RELEAEIASLERRKS 436
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 300-540 6.55e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 39.56  E-value: 6.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 300 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFLEWQKKMQAK--DREEQLAASEcrrlqGKLSHEEAILARQSLMQEN 377
Cdd:COG5185   267 LEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKAteSLEEQLAAAE-----AEQELEESKRETETGIQNL 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 378 KQRVEQQKEQMaklmlQHAETRLREDRSRKQLVEQVIEGQKNVKAAQTKLTKGRR---QTVQEVIEESRGLLRRRAQAAQ 454
Cdd:COG5185   342 TAEIEQGQESL-----TENLEAIKEEIENIVGEVELSKSSEELDSFKDTIESTKEsldEIPQNQRGYAQEILATLEDTLK 416

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339 455 EEQRRRCELISQLRALETQPTRKGKLVDltqtpgyglegeMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQ 534
Cdd:COG5185   417 AADRQIEELQRQIEQATSSNEEVSKLLN------------ELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLN 484


                  ....*.
gi 1622938339 535 NTVEQI 540
Cdd:COG5185   485 EELTQI 490
mukB PRK04863
chromosome partition protein MukB;
364-632 6.60e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 39.94  E-value: 6.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  364 EEAILARQSLMQENKQRVEQQK---EQMAKL-MLQHAETRLRED----RSRKQLVEQVIEGQKNVKAAQTKLTK--GRRQ 433
Cdd:PRK04863   286 EEALELRRELYTSRRQLAAEQYrlvEMARELaELNEAESDLEQDyqaaSDHLNLVQTALRQQEKIERYQADLEEleERLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  434 TVQEVIEESRGLL---RRRAQAAQEEQRrrcELISQL----RALETQPTRKG----------KLVDLTQTPGYGLEGems 496
Cdd:PRK04863   366 EQNEVVEEADEQQeenEARAEAAEEEVD---ELKSQLadyqQALDVQQTRAIqyqqavqaleRAKQLCGLPDLTADN--- 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622938339  497 iveLRERLALLkenqRRKEEEKRDQIIQGKRtKSQELQNTVEQ-----ISLCRAA--MGRSAALRWEeKKALAAAPEAPS 569
Cdd:PRK04863   440 ---AEDWLEEF----QAKEQEATEELLSLEQ-KLSVAQAAHSQfeqayQLVRKIAgeVSRSEAWDVA-RELLRRLREQRH 510

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622938339  570 QDERVQQLRRRISE--------RAAERSR----QAALLHVSAPRAAgPKPRAQLEAQ---HWLELERSRERRLQALQQ 632
Cdd:PRK04863   511 LAEQLQQLRMRLSEleqrlrqqQRAERLLaefcKRLGKNLDDEDEL-EQLQEELEARlesLSESVSEARERRMALRQQ 587
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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