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Conserved domains on  [gi|1622934296|ref|XP_028703469|]
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tubby-related protein 1 [Macaca mulatta]

Protein Classification

tubby family protein( domain architecture ID 13314231)

tubby family protein plays an important role in maintenance and function of neuronal cells during post differentiation and development in mammals, and may participate in the abscisic acid (ABA) signaling pathway in plants

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tub pfam01167
Tub family;
295-536 3.42e-130

Tub family;


:

Pssm-ID: 460094  Cd Length: 251  Bit Score: 379.61  E-value: 3.42e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 295 LRPAPQGRTVRCRLTRDKKGMdrGMYPSYFLHLD---SEKKVFLLAGRKRKRSKTANYLISSDPTNLSRAGENFIGKLRS 371
Cdd:pfam01167   1 KQPGPRDGTIQCFIKRDKSGM--GLTPTYHLYLElspGDGGKFLLAARKRRRSTTSNYLISLDADDLSRGSNGYIGKLRS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 372 NLLGNRFTVFDN-----GQNPQRG----YSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNaS 442
Cdd:pfam01167  79 NFLGTKFTLYDNqppynGANPSKSrssfGSKKVSPGRYELAAVSYELNVLGTRGPRRMKVIIPSIPASGQQVPIQPQS-E 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 443 DGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLC 522
Cdd:pfam01167 158 SSLLEDFKSGRLDELLVLKNKPPRWNEQLQCYCLNFHGRVTVASVKNFQLVAPEDQDKVILQFGKVGKDMFTMDYRYPLS 237

                         250
                  ....*....|....
gi 1622934296 523 ALQAFAIALSSFDG 536
Cdd:pfam01167 238 AFQAFAICLSSFDT 251
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 15-241 2.95e-04

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 2.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296  15 DSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTE------APESPCPTGSKPRKPGAGRKGRPREEPSPD-PAQARAPQTV 87
Cdd:PTZ00449  584 DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPElldipkSPKRPESPKSPKRPPPPQRPSSPERPEGPKiIKSPKPPKSP 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296  88 YARFlrDPEAKKR----------DPRETflvaRAPDAEDEEEEEEEDEDDEEEEAEEKKEKILLPPKKPLKEKSSADlke 157
Cdd:PTZ00449  664 KPPF--DPKFKEKfyddyldaaaKSKET----KTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFE--- 734

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 158 rrakaqgPRGDLGSPNP-------PPKALRVRNKEAPAGEGTKMRKTKKKGSGEADKDpSGSPASARKSPAamflvgegS 230
Cdd:PTZ00449  735 -------PIGDPDAEQPddiefftPPEEERTFFHETPADTPLPDILAEEFKEEDIHAE-TGEPDEAMKRPD--------S 798

                         250
                  ....*....|.
gi 1622934296 231 PDKKALKKKGT 241
Cdd:PTZ00449  799 PSEHEDKPPGD 809
 
Name Accession Description Interval E-value
Tub pfam01167
Tub family;
295-536 3.42e-130

Tub family;


Pssm-ID: 460094  Cd Length: 251  Bit Score: 379.61  E-value: 3.42e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 295 LRPAPQGRTVRCRLTRDKKGMdrGMYPSYFLHLD---SEKKVFLLAGRKRKRSKTANYLISSDPTNLSRAGENFIGKLRS 371
Cdd:pfam01167   1 KQPGPRDGTIQCFIKRDKSGM--GLTPTYHLYLElspGDGGKFLLAARKRRRSTTSNYLISLDADDLSRGSNGYIGKLRS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 372 NLLGNRFTVFDN-----GQNPQRG----YSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNaS 442
Cdd:pfam01167  79 NFLGTKFTLYDNqppynGANPSKSrssfGSKKVSPGRYELAAVSYELNVLGTRGPRRMKVIIPSIPASGQQVPIQPQS-E 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 443 DGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLC 522
Cdd:pfam01167 158 SSLLEDFKSGRLDELLVLKNKPPRWNEQLQCYCLNFHGRVTVASVKNFQLVAPEDQDKVILQFGKVGKDMFTMDYRYPLS 237

                         250
                  ....*....|....
gi 1622934296 523 ALQAFAIALSSFDG 536
Cdd:pfam01167 238 AFQAFAICLSSFDT 251
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 15-241 2.95e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 2.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296  15 DSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTE------APESPCPTGSKPRKPGAGRKGRPREEPSPD-PAQARAPQTV 87
Cdd:PTZ00449  584 DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPElldipkSPKRPESPKSPKRPPPPQRPSSPERPEGPKiIKSPKPPKSP 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296  88 YARFlrDPEAKKR----------DPRETflvaRAPDAEDEEEEEEEDEDDEEEEAEEKKEKILLPPKKPLKEKSSADlke 157
Cdd:PTZ00449  664 KPPF--DPKFKEKfyddyldaaaKSKET----KTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFE--- 734

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 158 rrakaqgPRGDLGSPNP-------PPKALRVRNKEAPAGEGTKMRKTKKKGSGEADKDpSGSPASARKSPAamflvgegS 230
Cdd:PTZ00449  735 -------PIGDPDAEQPddiefftPPEEERTFFHETPADTPLPDILAEEFKEEDIHAE-TGEPDEAMKRPD--------S 798

                         250
                  ....*....|.
gi 1622934296 231 PDKKALKKKGT 241
Cdd:PTZ00449  799 PSEHEDKPPGD 809
 
Name Accession Description Interval E-value
Tub pfam01167
Tub family;
295-536 3.42e-130

Tub family;


Pssm-ID: 460094  Cd Length: 251  Bit Score: 379.61  E-value: 3.42e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 295 LRPAPQGRTVRCRLTRDKKGMdrGMYPSYFLHLD---SEKKVFLLAGRKRKRSKTANYLISSDPTNLSRAGENFIGKLRS 371
Cdd:pfam01167   1 KQPGPRDGTIQCFIKRDKSGM--GLTPTYHLYLElspGDGGKFLLAARKRRRSTTSNYLISLDADDLSRGSNGYIGKLRS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 372 NLLGNRFTVFDN-----GQNPQRG----YSTNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIRPRNaS 442
Cdd:pfam01167  79 NFLGTKFTLYDNqppynGANPSKSrssfGSKKVSPGRYELAAVSYELNVLGTRGPRRMKVIIPSIPASGQQVPIQPQS-E 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 443 DGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPLC 522
Cdd:pfam01167 158 SSLLEDFKSGRLDELLVLKNKPPRWNEQLQCYCLNFHGRVTVASVKNFQLVAPEDQDKVILQFGKVGKDMFTMDYRYPLS 237

                         250
                  ....*....|....
gi 1622934296 523 ALQAFAIALSSFDG 536
Cdd:pfam01167 238 AFQAFAICLSSFDT 251
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 15-241 2.95e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 2.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296  15 DSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTE------APESPCPTGSKPRKPGAGRKGRPREEPSPD-PAQARAPQTV 87
Cdd:PTZ00449  584 DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPElldipkSPKRPESPKSPKRPPPPQRPSSPERPEGPKiIKSPKPPKSP 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296  88 YARFlrDPEAKKR----------DPRETflvaRAPDAEDEEEEEEEDEDDEEEEAEEKKEKILLPPKKPLKEKSSADlke 157
Cdd:PTZ00449  664 KPPF--DPKFKEKfyddyldaaaKSKET----KTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFE--- 734

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622934296 158 rrakaqgPRGDLGSPNP-------PPKALRVRNKEAPAGEGTKMRKTKKKGSGEADKDpSGSPASARKSPAamflvgegS 230
Cdd:PTZ00449  735 -------PIGDPDAEQPddiefftPPEEERTFFHETPADTPLPDILAEEFKEEDIHAE-TGEPDEAMKRPD--------S 798

                         250
                  ....*....|.
gi 1622934296 231 PDKKALKKKGT 241
Cdd:PTZ00449  799 PSEHEDKPPGD 809
PRK01297 PRK01297
ATP-dependent RNA helicase RhlB; Provisional
 19-85 4.30e-03

ATP-dependent RNA helicase RhlB; Provisional


Pssm-ID: 234938 [Multi-domain]  Cd Length: 475  Bit Score: 39.90  E-value: 4.30e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622934296  19 EEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPgagRKGRPREEPSPDPAQARAPQ 85
Cdd:PRK01297   13 EAEQPAPAPPSPAAAPAPPPPAKTAAPATKAAAPAAAAPRAEKP---KKDKPRRERKPKPASLWKLE 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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