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Conserved domains on  [gi|1622925520|ref|XP_028701914|]
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A-kinase anchor protein 9 isoform X14 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3659-3740 2.46e-25

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


:

Pssm-ID: 463115  Cd Length: 77  Bit Score: 101.90  E-value: 2.46e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3659 KYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTdleviTNRPKGFTRFRSAVRVSIAISRMKFLVR 3738
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD-----RPSRKPRRKLKSAALAVIAIARMKRLAR 75


                   ..
gi 1622925520 3739 RW 3740
Cdd:pfam10495   76 EW 77
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 270-998 3.00e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 3.00e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  270 IRTHQQQLEEQDHLLEDYQKKKEdftmQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKA----ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  350 DKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNhkdsqfetdivqrmeQETQRK 429
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL---------------DELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  430 LEQLRAELDEMygQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQK 509
Cdd:TIGR02168  339 LAELEEKLEEL--KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  510 EKLKEELGVILE-----EKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKE 584
Cdd:TIGR02168  417 ERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  585 LELKHEAEvTNYKIKLEMLEKEKNAVLDRMAESQEAElERLRTQLLFSHEEELSKL-KEDLEIEHQInIEKLKDN----- 658
Cdd:TIGR02168  497 LQENLEGF-SEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAALGGRLQAVvVENLNAAKKA-IAFLKQNelgrv 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  659 ----LGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLkdLQQSLVNSKSEEMTLQINELQKEIEIL--- 731
Cdd:TIGR02168  574 tflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL--LGGVLVVDDLDNALELAKKLRPGYRIVtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  732 ------------RQEEKEKGTLE--QEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMlkihtpd 797
Cdd:TIGR02168  652 gdlvrpggvitgGSAKTNSSILErrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------- 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  798 NQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEvnyqELQEEYAcllKVKDD 877
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIE---QLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  878 LEDSknkqeleyKSKLKALNEELHLQRINPTTVKTKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEvtkREKLELSQ 957
Cdd:TIGR02168  798 LKAL--------REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA---AEIEELEE 866

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1622925520  958 RLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELE 998
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1804-2569 7.27e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 7.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1804 RLQAAVEKLLEAISETSSQLEHAKvTQTELMrESFRQKQEATESLKCQ------EDLRERLHEESRAREQLAVELSKAEG 1877
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLE-RQAEKA-ERYKELKAELRELELAllvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1878 VIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQL--LQETEK 1955
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLdeLAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1956 LMKEKLEvqcQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQE---KNAELMDLRQQNQALEKQLEKMRKFLdeQAIDRE 2032
Cdd:TIGR02168  341 ELEEKLE---ELKEELESLEAELEELEAELEELESRLEELEEQletLRSKVAQLELQIASLNNEIERLEARL--ERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2033 HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELE 2112
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2113 qALLVSADTFQK-----VEDRKQFGA----------VEAKPELSLEVQLQAERDAIDRKEKEITNLE-EQLEQ------- 2169
Cdd:TIGR02168  496 -RLQENLEGFSEgvkalLKNQSGLSGilgvlselisVDEGYEAAIEAALGGRLQAVVVENLNAAKKAiAFLKQnelgrvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2170 FREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL--GLAIKESDAVSTQDQHVL------------- 2234
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELAKKLrpgyrivtldgdl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2235 ----------FGKFAQIIQEKEVEIDQLNEQIMKLQQQLKIT--------TDNKVIEEKNELIRDLETQIECLMSDQECV 2296
Cdd:TIGR02168  655 vrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELekalaelrKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2297 KRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLdmviAEKLALEQQVETTNEEMTFTKNILKETNF 2376
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2377 KMNQLTQELFSLKRERESMEKIQSIPGKSVNMA---IDDMSKDKPELEVVLTEDALKSLENQTYLKSFEENGKGSIINLE 2453
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLeeqIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2454 TRLLQLES------TVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEKVAAALVSQIQLEAVQEYAKFCQ 2527
Cdd:TIGR02168  891 LLRSELEElseelrELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA 970

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1622925520 2528 DNQTISSEPERTNIQNLNQLREDEsgsnISALTLRISELESQ 2569
Cdd:TIGR02168  971 RRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQ 1008
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3046-3393 7.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 7.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3046 LSEIQALHAQMNGRKITLKREQENEKSSQELleyniqqkQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQ 3125
Cdd:COG1196    188 LERLEDILGELERQLEPLERQAEKAERYREL--------KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3126 TKLELETtlkaqhkhlKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSE---ERDKEELEDLKF 3202
Cdd:COG1196    260 AELAELE---------AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEerlEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3203 SLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQ 3282
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3283 sndgtgqsrpslpseDLLKELQKQLEEKHSRIVELLNETEKyKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHE 3362
Cdd:COG1196    411 ---------------ALLERLERLEEELEELEEALAELEEE-EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1622925520 3363 LQSKVEDLQRQLEEKRQQVYKLDLEGQRLQG 3393
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEG 505
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 161-365 3.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEMRVTYgTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQI 240
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEE-KALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  241 QFQQlQASETLRNSTHSS-----TAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKK 315
Cdd:COG4942    105 ELAE-LLRALYRLGRQPPlalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  316 VENSNK--EEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQ 365
Cdd:COG4942    184 EEERAAleALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3659-3740 2.46e-25

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 101.90  E-value: 2.46e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3659 KYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTdleviTNRPKGFTRFRSAVRVSIAISRMKFLVR 3738
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD-----RPSRKPRRKLKSAALAVIAIARMKRLAR 75


                   ..
gi 1622925520 3739 RW 3740
Cdd:pfam10495   76 EW 77
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 270-998 3.00e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 3.00e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  270 IRTHQQQLEEQDHLLEDYQKKKEdftmQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKA----ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  350 DKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNhkdsqfetdivqrmeQETQRK 429
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL---------------DELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  430 LEQLRAELDEMygQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQK 509
Cdd:TIGR02168  339 LAELEEKLEEL--KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  510 EKLKEELGVILE-----EKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKE 584
Cdd:TIGR02168  417 ERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  585 LELKHEAEvTNYKIKLEMLEKEKNAVLDRMAESQEAElERLRTQLLFSHEEELSKL-KEDLEIEHQInIEKLKDN----- 658
Cdd:TIGR02168  497 LQENLEGF-SEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAALGGRLQAVvVENLNAAKKA-IAFLKQNelgrv 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  659 ----LGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLkdLQQSLVNSKSEEMTLQINELQKEIEIL--- 731
Cdd:TIGR02168  574 tflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL--LGGVLVVDDLDNALELAKKLRPGYRIVtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  732 ------------RQEEKEKGTLE--QEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMlkihtpd 797
Cdd:TIGR02168  652 gdlvrpggvitgGSAKTNSSILErrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------- 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  798 NQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEvnyqELQEEYAcllKVKDD 877
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIE---QLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  878 LEDSknkqeleyKSKLKALNEELHLQRINPTTVKTKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEvtkREKLELSQ 957
Cdd:TIGR02168  798 LKAL--------REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA---AEIEELEE 866

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1622925520  958 RLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELE 998
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1804-2569 7.27e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 7.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1804 RLQAAVEKLLEAISETSSQLEHAKvTQTELMrESFRQKQEATESLKCQ------EDLRERLHEESRAREQLAVELSKAEG 1877
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLE-RQAEKA-ERYKELKAELRELELAllvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1878 VIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQL--LQETEK 1955
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLdeLAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1956 LMKEKLEvqcQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQE---KNAELMDLRQQNQALEKQLEKMRKFLdeQAIDRE 2032
Cdd:TIGR02168  341 ELEEKLE---ELKEELESLEAELEELEAELEELESRLEELEEQletLRSKVAQLELQIASLNNEIERLEARL--ERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2033 HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELE 2112
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2113 qALLVSADTFQK-----VEDRKQFGA----------VEAKPELSLEVQLQAERDAIDRKEKEITNLE-EQLEQ------- 2169
Cdd:TIGR02168  496 -RLQENLEGFSEgvkalLKNQSGLSGilgvlselisVDEGYEAAIEAALGGRLQAVVVENLNAAKKAiAFLKQnelgrvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2170 FREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL--GLAIKESDAVSTQDQHVL------------- 2234
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELAKKLrpgyrivtldgdl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2235 ----------FGKFAQIIQEKEVEIDQLNEQIMKLQQQLKIT--------TDNKVIEEKNELIRDLETQIECLMSDQECV 2296
Cdd:TIGR02168  655 vrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELekalaelrKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2297 KRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLdmviAEKLALEQQVETTNEEMTFTKNILKETNF 2376
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2377 KMNQLTQELFSLKRERESMEKIQSIPGKSVNMA---IDDMSKDKPELEVVLTEDALKSLENQTYLKSFEENGKGSIINLE 2453
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLeeqIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2454 TRLLQLES------TVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEKVAAALVSQIQLEAVQEYAKFCQ 2527
Cdd:TIGR02168  891 LLRSELEElseelrELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA 970

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1622925520 2528 DNQTISSEPERTNIQNLNQLREDEsgsnISALTLRISELESQ 2569
Cdd:TIGR02168  971 RRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQ 1008
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 173-790 8.47e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.52  E-value: 8.47e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  173 ELNRELEEMRVTYGtegLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLR 252
Cdd:COG1196    217 ELKEELKELEAELL---LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  253 NSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKvensnKEEIQEKETIIE 332
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA-----EAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  333 ELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDs 412
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA- 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  413 qfetdivQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMN 492
Cdd:COG1196    448 -------AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  493 VAINELNIKLQDTNSQKEKLKEELGVILEEK-CALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDL 571
Cdd:COG1196    521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIvVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQIN 651
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  652 IEKLKDNLGIHYKQQIDGLQNEMSQKIEtmqfekdnlitkQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 731
Cdd:COG1196    681 LEELAERLAEEELELEEALLAEEEEERE------------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520  732 RQEEKEKGTLEQEVQELQLKIELLEKQMKEKE----------NDLQEKFTQLEAENSILKDEKKALEDM 790
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEALGpvnllaieeyEELEERYDFLSEQREDLEEARETLEEA 817
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1804-2374 1.08e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 1.08e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1804 RLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYA 1883
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1884 DEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQL--LQETEKLMKEKL 1961
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLeeLEEAEEALLERL 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1962 EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDE--QAIDREHERDVFQ 2039
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEllEELAEAAARLLLL 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2040 QEIQKLEQQLKVVPRFQPISEHQTREVEQLtnHLKEKTDKCSELLLSkEQLQRDIQERNEEIEKLEFRVRELEQALLVSA 2119
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAV--AVLIGVEAAYEAALE-AALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2120 DTFQKVEDRKQFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFR----EELENKNEEVQQLHMQLEIQKKES 2195
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlvaARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2196 TTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEK 2275
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2276 NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIG---QKTLVDAHSLPEEADSLKHQLDMVIAEKLA 2352
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGpvnLLAIEEYEELEERYDFLSEQREDLEEARET 813

                          570       580
                   ....*....|....*....|..
gi 1622925520 2353 LEQQVETTNEEMtftKNILKET 2374
Cdd:COG1196    814 LEEAIEEIDRET---RERFLET 832
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 195-988 5.61e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 72.31  E-value: 5.61e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  195 EFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLrnsthsSTAADLLQAKQQIRTHQ 274
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQL------KEKLELEEEYLLYLDYL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  275 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKvyEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTA 354
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEE--EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKV 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  355 ADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGT-VEELQKRNHKDSQFETDIVQRMEQETQRKLEQL 433
Cdd:pfam02463  311 DDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEeEEELEKLQEKLEQLEEELLAKKKLESERLSSAA 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  434 RAELDEMYGQQIVQMKQELIRQHVSQMEELKTRHKgemeNALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLK 513
Cdd:pfam02463  391 KLKEEELELKSEEEKEAQLLLELARQLEDLLKEEK----KEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  514 EELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKaeivSASESRKELELKHEAEV 593
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRII----SAHGRLGDLGVAVENYK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  594 TNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNE 673
Cdd:pfam02463  543 VAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRA 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  674 MSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIE 753
Cdd:pfam02463  623 KVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIK 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  754 LLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLifiDSIKSKSKDSVWEKEIEILTEENEDLK 833
Cdd:pfam02463  703 KKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  834 QQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKTK 913
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  914 SSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKE 988
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3046-3393 7.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 7.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3046 LSEIQALHAQMNGRKITLKREQENEKSSQELleyniqqkQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQ 3125
Cdd:COG1196    188 LERLEDILGELERQLEPLERQAEKAERYREL--------KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3126 TKLELETtlkaqhkhlKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSE---ERDKEELEDLKF 3202
Cdd:COG1196    260 AELAELE---------AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEerlEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3203 SLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQ 3282
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3283 sndgtgqsrpslpseDLLKELQKQLEEKHSRIVELLNETEKyKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHE 3362
Cdd:COG1196    411 ---------------ALLERLERLEEELEELEEALAELEEE-EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1622925520 3363 LQSKVEDLQRQLEEKRQQVYKLDLEGQRLQG 3393
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
495-990 9.49e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 9.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  495 INELNIKLQDTNSQKEKL---KEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDL 571
Cdd:PRK03918   209 INEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSASESRKELElKHEAEVTNYKIKLEMLEKEKNAVLDRM--AESQEAELERLRtQLLFSHEEELSKLKEDLEIEHQ 649
Cdd:PRK03918   289 KEKAEEYIKLSEFYE-EYLDELREIEKRLSRLEEEINGIEERIkeLEEKEERLEELK-KKLKELEKRLEELEERHELYEE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  650 I-----NIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL--QIN 722
Cdd:PRK03918   367 AkakkeELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgrELT 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  723 ELQKEiEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLqEKFTQLEAENSILkDEKKALEDMLKIHT-----PD 797
Cdd:PRK03918   447 EEHRK-ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL-KKESELIKLKELA-EQLKELEEKLKKYNleeleKK 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  798 NQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNE------EIEKQRNTFSF-AEKNFEVNYQELQE---E 867
Cdd:PRK03918   524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDEleeelaELLKELEELGFeSVEELEERLKELEPfynE 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  868 YACLLKVKDDLEDSKNKQELEyKSKLKALNEELhlQRINPTTVKTKSSVFDEDKTFVAETLEMgevVEKDTTELMEKLEV 947
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKL-EEELDKAFEEL--AETEKRLEELRKELEELEKKYSEEEYEE---LREEYLELSRELAG 677

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1622925520  948 TKREKLELSQRLADLS---EQLKQKHGEISFLNEEVKSLKQEKEQV 990
Cdd:PRK03918   678 LRAELEELEKRREEIKktlEKLKEELEEREKAKKELEKLEKALERV 723
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3083-3401 1.74e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3083 QKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLN 3162
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3163 DTLASEQKKSRELQWALEKEKAKLGHSEERdKEELEDLKFSLESQkqrnlqlnllleqqkqlLDESQQKIESQRMLYDAQ 3242
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEE-LAEAEAEIEELEAQ-----------------IEQLKEELKALREALDEL 808

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3243 LSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSNDGTGQSrpslpSEDLLKELQKQLEEKHSRIVELLNEte 3322
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES-----LAAEIEELEELIEELESELEALLNE-- 881

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520 3323 kykldslqtRQQMEKDRQVHRKTLQTEQEantegqkKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQ 3401
Cdd:TIGR02168  882 ---------RASLEEALALLRSELEELSE-------ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2087-2735 7.95e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 7.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2087 KEQLQRDIQERNEEIEKLEFRVRELEQallvsadtfqkVEDRKQFGAVEAKPELSLEVQ-LQAERDAI----DRKEKEIT 2161
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNE-----------LHEKQKFYLRQSVIDLQTKLQeMQMERDAMadirRRESQSQE 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2162 NLEEQLEQFREELEN----KNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGK 2237
Cdd:pfam15921  142 DLRNQLQNTVHELEAakclKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSA 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2238 FAQIIQEKEVEIDQLNEQIMKLQQQ---LKITTDNKVieekNELIRDLETQIECLMSDQE----------CVKRNREEEI 2304
Cdd:pfam15921  222 ISKILRELDTEISYLKGRIFPVEDQleaLKSESQNKI----ELLLQQHQDRIEQLISEHEveitgltekaSSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2305 EQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKL-ALEQQVETTNEEMTFTKNILKETNFKMNQLTQ 2383
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIeELEKQLVLANSELTEARTERDQFSQESGNLDD 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2384 ELFSL-----KRERE-SMEKIQ-----------SIPGKSVNMAIDDMSKDKPELEVVLTedALKS-LENQTYLKSFEENG 2445
Cdd:pfam15921  378 QLQKLladlhKREKElSLEKEQnkrlwdrdtgnSITIDHLRRELDDRNMEVQRLEALLK--AMKSeCQGQMERQMAAIQG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2446 KG-SIINLETRLLQLEST----------VRAKDLELTQCYKQIKDMQ----------EQGQSEIEVLQKKI-LNLQKILE 2503
Cdd:pfam15921  456 KNeSLEKVSSLTAQLESTkemlrkvveeLTAKKMTLESSERTVSDLTaslqekeraiEATNAEITKLRSRVdLKLQELQH 535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2504 EKVAAALVSQIQLEAVQEYAKFCQDNQTIssEPERTNIQNLNQLrEDESGSNISALTLRISELESQLVEMHTSL-----I 2578
Cdd:pfam15921  536 LKNEGDHLRNVQTECEALKLQMAEKDKVI--EILRQQIENMTQL-VGQHGRTAGAMQVEKAQLEKEINDRRLELqefkiL 612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2579 LGKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQGGKERKRSPQDF--EVLKTTTELFHSNEE-----SGFLNELEALRA 2651
Cdd:pfam15921  613 KDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLlnEVKTSRNELNSLSEDyevlkRNFRNKSEEMET 692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2652 ESVATKAQLTGYKEKTEKLQGELLIKETN-------MASLQKDLSQVRDHLAEAKEKLSILEKEDKTAvqeNKKACMFKP 2724
Cdd:pfam15921  693 TTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvAMGMQKQITAKRGQIDALQSKIQFLEEAMTNA---NKEKHFLKE 769

                          730
                   ....*....|.
gi 1622925520 2725 LPVKLSKSIAS 2735
Cdd:pfam15921  770 EKNKLSQELST 780
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1968-2504 1.52e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 1.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1968 EKVRDDLQKQVKALEiDVEEQVSRFIELEQEKNAELMDLRQQNQAlEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQ 2047
Cdd:PRK03918   144 DESREKVVRQILGLD-DYENAYKNLGEVIKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELRE 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2048 QLKVVprfqpisEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEqallvsadtfQKVED 2127
Cdd:PRK03918   222 ELEKL-------EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE----------EKVKE 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2128 RKQFGAvEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFRE---ELENKNEEVQqlhmQLEIQKKESTTRLQELEQ 2204
Cdd:PRK03918   285 LKELKE-KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEErikELEEKEERLE----ELKKKLKELEKRLEELEE 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2205 ENKLFKDDMEKLGlaikESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQqlKITTDNKVIEEKNELIRDLET 2284
Cdd:PRK03918   360 RHELYEEAKAKKE----ELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA--RIGELKKEIKELKKAIEELKK 433

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2285 qieclmSDQECVKRNREEEIEQLNEVIEKLQQELANIgQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQvETTNEEM 2364
Cdd:PRK03918   434 ------AKGKCPVCGRELTEEHRKELLEEYTAELKRI-EKELKEIEEKERKLRKELRELEKVLKKESELIKL-KELAEQL 505

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2365 TFTKNILKETNF-KMNQLTQELFSLKRERESMEKIQSIPGKSVNmAIDDMSKDKPELEVVL--TEDALKSLENQtylksF 2441
Cdd:PRK03918   506 KELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLdeLEEELAELLKE-----L 579

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622925520 2442 EENGKGSIINLETRLLQLESTVRaKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEE 2504
Cdd:PRK03918   580 EELGFESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKR 641
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 161-365 3.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEMRVTYgTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQI 240
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEE-KALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  241 QFQQlQASETLRNSTHSS-----TAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKK 315
Cdd:COG4942    105 ELAE-LLRALYRLGRQPPlalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  316 VENSNK--EEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQ 365
Cdd:COG4942    184 EEERAAleALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PTZ00121 PTZ00121
MAEBL; Provisional
 3029-3401 5.59e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.84  E-value: 5.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3029 EYQAAMEYLQKADRRSLLSEIQALHAQMNGRKITLKREQENEKSSQELLEYNIQQKQSQMLEMQVElssMKDRATELQEQ 3108
Cdd:PTZ00121  1376 AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE---EAKKADEAKKK 1452

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3109 lSSEKMVVAELRSELAQTKLELETTLKAQH-KHLKELEAFRLEVKDKTDEVHllndTLASEQKKSRELQWALEKEKAKLG 3187
Cdd:PTZ00121  1453 -AEEAKKAEEAKKKAEEAKKADEAKKKAEEaKKADEAKKKAEEAKKKADEAK----KAAEAKKKADEAKKAEEAKKADEA 1527

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3188 HSEErDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEhgrnlelqvLLESEKVRIREM 3267
Cdd:PTZ00121  1528 KKAE-EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE---------AKKAEEARIEEV 1597

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3268 SSTLDRERELHAQL-----QSNDGTGQSRPSLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVH 3342
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEakkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 3343 RKTLQTEQEAN--TEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQ 3401
Cdd:PTZ00121  1678 EEAKKAEEDEKkaAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE 1738
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 2088-2317 2.13e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.47  E-value: 2.13e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  2088 EQLQRDIQERNEEIEKLEFRVRELEQALLV---SADTFQKVEDRKQFGAVEAKPELslevqlQAERDAIDRKEKEITNLE 2164
Cdd:smart00787   73 KELKKYISEGRDLFKEIEEETLINNPPLFKeyfSASPDVKLLMDKQFQLVKTFARL------EAKKMWYEWRMKLLEGLK 146

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  2165 EQLEQFREELENKNEEVQQ-------LHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKEsdAVSTQDQHvlfgk 2237
Cdd:smart00787  147 EGLDENLEGLKEDYKLLMKelellnsIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKE--KLKKLLQE----- 219

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  2238 faqiIQEKEVEIDQLNEQIMKLQQqlkittdnkVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQE 2317
Cdd:smart00787  220 ----IMIKVKKLEELEEELQELES---------KIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3168-3400 7.81e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 7.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3168 EQKKSRELQWALEKEKAKLGHSEERDKE-----ELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQ 3242
Cdd:pfam17380  305 KEEKAREVERRRKLEEAEKARQAEMDRQaaiyaEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQ 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3243 LSEEHGRNLELQVLLESEKVRIREMsstlDRERELHAQLQSNDGTGQSRpslpsEDLLKELQKQLEEKHSRivellnETE 3322
Cdd:pfam17380  385 MERQQKNERVRQELEAARKVKILEE----ERQRKIQQQKVEMEQIRAEQ-----EEARQREVRRLEEERAR------EME 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3323 KYKLDSLQTRQQMEKDRQ--VHRKTLQTEQEANTEGQKKMHELQSKVedLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQK 3400
Cdd:pfam17380  450 RVRLEEQERQQQVERLRQqeEERKRKKLELEKEKRDRKRAEEQRRKI--LEKELEERKQAMIEEERKRKLLEKEMEERQK 527
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 664-793 9.93e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 9.93e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520   664 KQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLV--------------NSKSEEMTLQINELQK--- 726
Cdd:smart00787  139 MKLLEGLKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEeelrqlkqledeleDCDPTELDRAKEKLKKllq 218

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520   727 EIEILRQEEKEkgtLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKI 793
Cdd:smart00787  219 EIMIKVKKLEE---LEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKL 282
 
Name Accession Description Interval E-value
PACT_coil_coil pfam10495
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ...
 3659-3740 2.46e-25

Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.


Pssm-ID: 463115  Cd Length: 77  Bit Score: 101.90  E-value: 2.46e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3659 KYLRAESFRKALIYQKKYLLLLLGGFQECEDATLALLARMGGQPAFTdleviTNRPKGFTRFRSAVRVSIAISRMKFLVR 3738
Cdd:pfam10495    1 KLLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDD-----RPSRKPRRKLKSAALAVIAIARMKRLAR 75


                   ..
gi 1622925520 3739 RW 3740
Cdd:pfam10495   76 EW 77
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 270-998 3.00e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 3.00e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  270 IRTHQQQLEEQDHLLEDYQKKKEdftmQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKELKA----ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  350 DKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNhkdsqfetdivqrmeQETQRK 429
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL---------------DELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  430 LEQLRAELDEMygQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQK 509
Cdd:TIGR02168  339 LAELEEKLEEL--KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  510 EKLKEELGVILE-----EKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKE 584
Cdd:TIGR02168  417 ERLQQEIEELLKkleeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  585 LELKHEAEvTNYKIKLEMLEKEKNAVLDRMAESQEAElERLRTQLLFSHEEELSKL-KEDLEIEHQInIEKLKDN----- 658
Cdd:TIGR02168  497 LQENLEGF-SEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAALGGRLQAVvVENLNAAKKA-IAFLKQNelgrv 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  659 ----LGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLkdLQQSLVNSKSEEMTLQINELQKEIEIL--- 731
Cdd:TIGR02168  574 tflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL--LGGVLVVDDLDNALELAKKLRPGYRIVtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  732 ------------RQEEKEKGTLE--QEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMlkihtpd 797
Cdd:TIGR02168  652 gdlvrpggvitgGSAKTNSSILErrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------- 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  798 NQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEvnyqELQEEYAcllKVKDD 877
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIE---QLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  878 LEDSknkqeleyKSKLKALNEELHLQRINPTTVKTKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEvtkREKLELSQ 957
Cdd:TIGR02168  798 LKAL--------REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA---AEIEELEE 866

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1622925520  958 RLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELE 998
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-884 4.06e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 4.06e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  207 ITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLED 286
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  287 YQKKKEDFTMQISFLQEKIkvyemEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQV 366
Cdd:TIGR02168  314 LERQLEELEAQLEELESKL-----DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  367 VQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNH----KDSQFETDIVQRMEQETQRKLEQLRAELDEMyg 442
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeaelKELQAELEELEEELEELQEELERLEEALEEL-- 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  443 QQIVQMKQELIRQHVSQMEELKTRHKG--EMENALRSYP----NITVNEDQIK--------------------------- 489
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSleRLQENLEGFSegvkALLKNQSGLSgilgvlselisvdegyeaaieaalggr 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  490 LMNVAINELNIKLQDTNSQKEKLKEELGVI-------------------------------------------------- 519
Cdd:TIGR02168  547 LQAVVVENLNAAKKAIAFLKQNELGRVTFLpldsikgteiqgndreilkniegflgvakdlvkfdpklrkalsyllggvl 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  520 ----LEEKCALQRQL-----------------------EDLFEELSFSREQ-IQRARQTIAEQESKLNEAQKSLSTVEDL 571
Cdd:TIGR02168  627 vvddLDNALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRReIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMA-------------ESQEAELERLRTQLLfSHEEELS 638
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAqlskelteleaeiEELEERLEEAEEELA-EAEAEIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  639 KLKEDLE---IEHQINIEKLKDNLGIHYKQQIDGLQNEmsQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLvNSKSE 715
Cdd:TIGR02168  786 ELEAQIEqlkEELKALREALDELRAELTLLNEEAANLR--ERLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  716 EMTLQINELQKEIEILrqeEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMlkiht 795
Cdd:TIGR02168  863 ELEELIEELESELEAL---LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL----- 934

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  796 pdnQEERLIFIDSIKSKSKDS--VWEKEIEILTEENEDLKQQCIQLNEEIEkqrntfSFAEKNFEV--NYQELQEEYACL 871
Cdd:TIGR02168  935 ---EVRIDNLQERLSEEYSLTleEAEALENKIEDDEEEARRRLKRLENKIK------ELGPVNLAAieEYEELKERYDFL 1005

                          810
                   ....*....|...
gi 1622925520  872 LKVKDDLEDSKNK 884
Cdd:TIGR02168 1006 TAQKEDLTEAKET 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1804-2569 7.27e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 7.27e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1804 RLQAAVEKLLEAISETSSQLEHAKvTQTELMrESFRQKQEATESLKCQ------EDLRERLHEESRAREQLAVELSKAEG 1877
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLE-RQAEKA-ERYKELKAELRELELAllvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1878 VIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQL--LQETEK 1955
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLdeLAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1956 LMKEKLEvqcQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQE---KNAELMDLRQQNQALEKQLEKMRKFLdeQAIDRE 2032
Cdd:TIGR02168  341 ELEEKLE---ELKEELESLEAELEELEAELEELESRLEELEEQletLRSKVAQLELQIASLNNEIERLEARL--ERLEDR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2033 HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELE 2112
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2113 qALLVSADTFQK-----VEDRKQFGA----------VEAKPELSLEVQLQAERDAIDRKEKEITNLE-EQLEQ------- 2169
Cdd:TIGR02168  496 -RLQENLEGFSEgvkalLKNQSGLSGilgvlselisVDEGYEAAIEAALGGRLQAVVVENLNAAKKAiAFLKQnelgrvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2170 FREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL--GLAIKESDAVSTQDQHVL------------- 2234
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELAKKLrpgyrivtldgdl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2235 ----------FGKFAQIIQEKEVEIDQLNEQIMKLQQQLKIT--------TDNKVIEEKNELIRDLETQIECLMSDQECV 2296
Cdd:TIGR02168  655 vrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELekalaelrKELEELEEELEQLRKELEELSRQISALRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2297 KRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLdmviAEKLALEQQVETTNEEMTFTKNILKETNF 2376
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2377 KMNQLTQELFSLKRERESMEKIQSIPGKSVNMA---IDDMSKDKPELEVVLTEDALKSLENQTYLKSFEENGKGSIINLE 2453
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLeeqIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2454 TRLLQLES------TVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEKVAAALVSQIQLEAVQEYAKFCQ 2527
Cdd:TIGR02168  891 LLRSELEElseelrELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEA 970

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1622925520 2528 DNQTISSEPERTNIQNLNQLREDEsgsnISALTLRISELESQ 2569
Cdd:TIGR02168  971 RRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQ 1008
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 154-968 2.02e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 87.05  E-value: 2.02e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  154 LTHLEMMESELAGKQHEIEELNRELEEMRVtygteglqQLQEFEAAIKQRDGIITQLtanlqqARREKDETMREFLELTE 233
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEELEKLTE--------EISELEKRLEEIEQLLEEL------NKKIKDLGEEEQLRVKE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  234 QSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKI--KVYEME 311
Cdd:TIGR02169  295 KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELedLRAELE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  312 QDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSS 391
Cdd:TIGR02169  375 EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  392 EEIKQLMGTVEELQKRNHKDSQfETDIVQRMEQETQRKLEQLRAELD-----EMYGQQIVQMKQELIRQ---HVSQMEEL 463
Cdd:TIGR02169  455 WKLEQLAADLSKYEQELYDLKE-EYDRVEKELSKLQRELAEAEAQARaseerVRGGRAVEEVLKASIQGvhgTVAQLGSV 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  464 KTRHKGEMENALRSYPNITVNED------------QIKLMNVAINELNiKLQDTNSQKEKLKEElGVI--------LEEK 523
Cdd:TIGR02169  534 GERYATAIEVAAGNRLNNVVVEDdavakeaiellkRRKAGRATFLPLN-KMRDERRDLSILSED-GVIgfavdlveFDPK 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  524 --CALQRQLED--LFEELSFSREQIQRARQTIAEQEskLNEAQKSLS--TVEDLKAEIVSASESRKELELKHEaevtnyk 597
Cdd:TIGR02169  612 yePAFKYVFGDtlVVEDIEAARRLMGKYRMVTLEGE--LFEKSGAMTggSRAPRGGILFSRSEPAELQRLRER------- 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  598 ikLEMLEKEKNAVLDRMAEsQEAELERLRTQLLFSHEE--ELSKLKEDLEIEHQINIEKLKdnlgihykqQIDGLQNEMS 675
Cdd:TIGR02169  683 --LEGLKRELSSLQSELRR-IENRLDELSQELSDASRKigEIEKEIEQLEQEEEKLKERLE---------ELEEDLSSLE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  676 QKIETMQFEKDNLITKQNQLILEISKLK----DLQQSLVNSKSEEMTLQINELQKEI-----------EILRQEEKEKGT 740
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEealnDLEARLSHSRIPEIQAELSKLEEEVsriearlreieQKLNRLTLEKEY 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  741 LEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMlkihtpdnqEERLIFIdsikskskdsvwEK 820
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL---------ESRLGDL------------KK 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  821 EIEILTEENEDLKQQCIQLNEEIEKQRNTFsfaeKNFEVNYQELQEEYACLLK-VKDDLEDSKNKQELE-YKSKLKALNE 898
Cdd:TIGR02169  890 ERDELEAQLRELERKIEELEAQIEKKRKRL----SELKAKLEALEEELSEIEDpKGEDEEIPEEELSLEdVQAELQRVEE 965

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  899 ELhlQRINPTTVKTkssvfdedktfvaetLEMGEVVEKDTTELMEKLEVTKREKLELSQRLADLSEQLKQ 968
Cdd:TIGR02169  966 EI--RALEPVNMLA---------------IQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 173-988 1.61e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 1.61e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  173 ELNRELEEMRVTYgteglqQLQEFEAAIKQRDgiitQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLR 252
Cdd:TIGR02168  217 ELKAELRELELAL------LVLRLEELREELE----ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  253 NSTHSSTAADLLQAKQQIRTHQQQLEEqdhlLEDYQKKKEDftmQISFLQEKIkvyemEQDKKVENSNKEEIQEKETIIE 332
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLAN----LERQLEELEA---QLEELESKL-----DELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  333 ELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNH--- 409
Cdd:TIGR02168  355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeae 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  410 -KDSQFETDIVQRMEQETQRKLEQLRAELDEMygQQIVQMKQELIRQHVSQMEELKTRHKG--EMENALRSYP----NIT 482
Cdd:TIGR02168  435 lKELQAELEELEEELEELQEELERLEEALEEL--REELEEAEQALDAAERELAQLQARLDSleRLQENLEGFSegvkALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  483 VNEDQIK-LMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQ-ESKLNE 560
Cdd:TIGR02168  513 KNQSGLSgILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEiQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  561 AQKSLSTVEDLKAEIVSASES-RKELE--LKHEAEVTNYKIKLEMLEKEKnavLDRMAESQEAEL----------ERLRT 627
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKlRKALSylLGGVLVVDDLDNALELAKKLR---PGYRIVTLDGDLvrpggvitggSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  628 QLLFSHEEELSKLKEDLEiEHQINIEKLKDNLgihykQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQ 707
Cdd:TIGR02168  670 SSILERRREIEELEEKIE-ELEEKIAELEKAL-----AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  708 SLvnskSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKAL 787
Cdd:TIGR02168  744 QL----EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  788 edmlkihtpDNQEERLifidsIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEE 867
Cdd:TIGR02168  820 ---------ANLRERL-----ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  868 YACLLKVKDDLEDsKNKQELEYKSKLKALNEELHLQRINPTTVKTKSSVFDEDktfVAETLEMGEVVEKDTTELMEKLEV 947
Cdd:TIGR02168  886 EEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR---IDNLQERLSEEYSLTLEEAEALEN 961

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1622925520  948 TKREKLELSQRLADLSEQLKQKHGEISFLN-EEVKSLKQEKE 988
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKELGPVNLAAiEEYEELKERYD 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 173-790 8.47e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.52  E-value: 8.47e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  173 ELNRELEEMRVTYGtegLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLR 252
Cdd:COG1196    217 ELKEELKELEAELL---LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  253 NSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKvensnKEEIQEKETIIE 332
Cdd:COG1196    294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA-----EAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  333 ELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDs 412
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA- 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  413 qfetdivQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMN 492
Cdd:COG1196    448 -------AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  493 VAINELNIKLQDTNSQKEKLKEELGVILEEK-CALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDL 571
Cdd:COG1196    521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIvVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQIN 651
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  652 IEKLKDNLGIHYKQQIDGLQNEMSQKIEtmqfekdnlitkQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 731
Cdd:COG1196    681 LEELAERLAEEELELEEALLAEEEEERE------------LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520  732 RQEEKEKGTLEQEVQELQLKIELLEKQMKEKE----------NDLQEKFTQLEAENSILKDEKKALEDM 790
Cdd:COG1196    749 EEEALEELPEPPDLEELERELERLEREIEALGpvnllaieeyEELEERYDFLSEQREDLEEARETLEEA 817
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 150-772 1.12e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.14  E-value: 1.12e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  150 AQYSLTHLEMMESELAGKQHEIEELNRELEEMRvtygteglQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFL 229
Cdd:COG1196    227 AELLLLKLRELEAELEELEAELEELEAELEELE--------AELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  230 ELTEQSQKLQIQFQQLQASETlrnsthsSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYE 309
Cdd:COG1196    299 RLEQDIARLEERRRELEERLE-------ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  310 MEQDKKVE--NSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKE 387
Cdd:COG1196    372 AELAEAEEelEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  388 RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK-----QELIRQHVSQMEE 462
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAlllagLRGLAGAVAVLIG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  463 LKTRHKGEMENALRSYPNITVNEDQIKLMNvAINELNIK-------LQDTNSQKEKLKEELGVILEEKCALQRQLEDLFE 535
Cdd:COG1196    532 VEAAYEAALEAALAAALQNIVVEDDEVAAA-AIEYLKAAkagratfLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  536 ELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEvtnykIKLEMLEKEKNAVLDRMA 615
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR-----RELLAALLEAEAELEELA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  616 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL 695
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520  696 ILEISKLKDLQQSL--VNSKSEEmtlQINELQKEIEILrqeEKEKGTLEQEVQELQLKIELLEKQMKEKendLQEKFTQ 772
Cdd:COG1196    766 ERELERLEREIEALgpVNLLAIE---EYEELEERYDFL---SEQREDLEEARETLEEAIEEIDRETRER---FLETFDA 835
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1984-2387 2.97e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 2.97e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1984 DVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQT 2063
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2064 REVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfgaveakpelSLE 2143
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE----------SLE 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2144 VQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKEsttrLQELEQENKLFKDDMEKLGLAIKES 2223
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE----RASLEEALALLRSELEELSEELREL 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2224 DAVSTQDQHVL------FGKFAQIIQEKEVEIDQLNEQIMklqqqlkittdnkvieekNELIRDLETQIEClmsdqecvK 2297
Cdd:TIGR02168  907 ESKRSELRRELeelrekLAQLELRLEGLEVRIDNLQERLS------------------EEYSLTLEEAEAL--------E 960

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2298 RNREEEIEQLNEVIEKLQQELANIGQKTLV---DAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMtftKNILKET 2374
Cdd:TIGR02168  961 NKIEDDEEEARRRLKRLENKIKELGPVNLAaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREA---RERFKDT 1037

                          410
                   ....*....|...
gi 1622925520 2375 NFKMNQLTQELFS 2387
Cdd:TIGR02168 1038 FDQVNENFQRVFP 1050
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 133-898 3.06e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.11  E-value: 3.06e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  133 LLREEEFGVDDSYSEQGAQYSlTHLEMMESELAGKQHEIEELNRELEEMRvtygteglQQLQEFEAAIKQRDGIITQLTA 212
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRVK-EKIGELEAEIASLERSIAEKERELEDAE--------ERLAKLEAEIDKLLAEIEELER 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  213 NLQQARREKDETMREFLELTEQSQKLQIQFQQLQAsetlrnsTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKE 292
Cdd:TIGR02169  344 EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK-------EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  293 DFTMQISFLQEKIKVYEMEQDK--KVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKN 370
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINEleEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  371 QEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELqkrnhkdSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 450
Cdd:TIGR02169  497 AQARASEERVRGGRAVEEVLKASIQGVHGTVAQL-------GSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKR 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  451 E---------LIRQHVSQMEELKTRHKGEMENAL------RSYPNI-------TVNEDQI----KLMNV----------- 493
Cdd:TIGR02169  570 RkagratflpLNKMRDERRDLSILSEDGVIGFAVdlvefdPKYEPAfkyvfgdTLVVEDIeaarRLMGKyrmvtlegelf 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  494 ----AINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLstvE 569
Cdd:TIGR02169  650 eksgAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI---E 726

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  570 DLKAEIVSASESRKELELKHEA---EVTNYKIKLEMLEKEKNAvLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEI 646
Cdd:TIGR02169  727 QLEQEEEKLKERLEELEEDLSSleqEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEE 805

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  647 EHqinieklkdnlgihykQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDlQQSLVNSKSEEMTLQINELQK 726
Cdd:TIGR02169  806 EV----------------SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE-QIKSIEKEIENLNGKKEELEE 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  727 EIEILRQEEKEkgtLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEdmlkihtpdNQEERLIFI 806
Cdd:TIGR02169  869 ELEELEAALRD---LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE---------ALEEELSEI 936

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  807 DSIKSKSKDSVWEKEIEilteenEDLKQQCIQLNEEIEKQRntfsfaeknfEVNYQELQeEYACLLKVKDDLEDSKNKQE 886
Cdd:TIGR02169  937 EDPKGEDEEIPEEELSL------EDVQAELQRVEEEIRALE----------PVNMLAIQ-EYEEVLKRLDELKEKRAKLE 999

                          810
                   ....*....|..
gi 1622925520  887 LEYKSKLKALNE 898
Cdd:TIGR02169 1000 EERKAILERIEE 1011
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1804-2374 1.08e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 1.08e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1804 RLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYA 1883
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1884 DEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQL--LQETEKLMKEKL 1961
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLeeLEEAEEALLERL 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1962 EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDE--QAIDREHERDVFQ 2039
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEllEELAEAAARLLLL 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2040 QEIQKLEQQLKVVPRFQPISEHQTREVEQLtnHLKEKTDKCSELLLSkEQLQRDIQERNEEIEKLEFRVRELEQALLVSA 2119
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAV--AVLIGVEAAYEAALE-AALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2120 DTFQKVEDRKQFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFR----EELENKNEEVQQLHMQLEIQKKES 2195
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlvaARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2196 TTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEK 2275
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2276 NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIG---QKTLVDAHSLPEEADSLKHQLDMVIAEKLA 2352
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGpvnLLAIEEYEELEERYDFLSEQREDLEEARET 813

                          570       580
                   ....*....|....*....|..
gi 1622925520 2353 LEQQVETTNEEMtftKNILKET 2374
Cdd:COG1196    814 LEEAIEEIDRET---RERFLET 832
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 321-884 2.53e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.53e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  321 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGT 400
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  401 VEELQKRNHKDSQfETDIVQRMEQETQRKLEQLRAELdemygQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRsypn 480
Cdd:COG1196    325 LAELEEELEELEE-ELEELEEELEEAEEELEEAEAEL-----AEAEEALLEAEAELAEAEEELEELAEELLEALRA---- 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  481 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNE 560
Cdd:COG1196    395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  561 AQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNA--------VLDRMAESQEAELERLRTQLLFS 632
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavavligVEAAYEAALEAALAAALQNIVVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  633 HEEELSKLKEDLEIE----------HQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKL 702
Cdd:COG1196    555 DDEVAAAAIEYLKAAkagratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  703 KDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKD 782
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  783 EKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEEN-EDLKQQCIQLNEEIEkqrntfsfaekNFE-VN 860
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDlEELERELERLEREIE-----------ALGpVN 783

                          570       580       590
                   ....*....|....*....|....*....|
gi 1622925520  861 ------YQELQEEYACLLKVKDDLEDSKNK 884
Cdd:COG1196    784 llaieeYEELEERYDFLSEQREDLEEARET 813
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 154-792 5.79e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 75.44  E-value: 5.79e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  154 LTHLEMMESELAGKQHEIEELNRELEEMR--VTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLEL 231
Cdd:TIGR04523  144 LTEIKKKEKELEKLNNKYNDLKKQKEELEneLNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISEL 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  232 TEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME 311
Cdd:TIGR04523  224 KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  312 QDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSS 391
Cdd:TIGR04523  304 KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYK 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  392 EEIKQLMGTVEELQKrnhkdsqfETDIVQRMEQETQRKLEQLRAELDEMyGQQIVQMKQELIRQH--VSQMEELKTRHKG 469
Cdd:TIGR04523  384 QEIKNLESQINDLES--------KIQNQEKLNQQKDEQIKKLQQEKELL-EKEIERLKETIIKNNseIKDLTNQDSVKEL 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  470 EMENALRSypnITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQ 549
Cdd:TIGR04523  455 IIKNLDNT---RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  550 TIAEQESKLNeaqkslstveDLKAEIVSASESRKELELkhEAEVTNYKIKLEMLEKEKNAVLDRMAESQEaELERLRTQL 629
Cdd:TIGR04523  532 EKKEKESKIS----------DLEDELNKDDFELKKENL--EKEIDEKNKEIEELKQTQKSLKKKQEEKQE-LIDQKEKEK 598

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  630 LFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLqqsl 709
Cdd:TIGR04523  599 KDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTK---- 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  710 vnskseemtlqineLQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKqmkekendLQEKFTQLEAENSILKDEKKALED 789
Cdd:TIGR04523  675 --------------IDDIIELMKDWLKELSLHYKKYITRMIRIKDLPK--------LEEKYKEIEKELKKLDEFSKELEN 732


                   ...
gi 1622925520  790 MLK 792
Cdd:TIGR04523  733 IIK 735
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2087-2708 1.59e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 1.59e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2087 KEQLQRDIQERNEEIEKLEFRVRELE--------QALLVSADTFQKVEDRKQFGAVEAKPELSLEVQLQAERDAIDRKEK 2158
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEDILNELErqlkslerQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2159 EITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKE---STTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVL- 2234
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyaLANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLd 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2235 -----FGKFAQIIQEKEVEIDQLNEQIMKLQQQL-----KITTDNKVIEEKNELIRDLETQIECLMSDQEcvkrNREEEI 2304
Cdd:TIGR02168  334 elaeeLAELEEKLEELKEELESLEAELEELEAELeelesRLEELEEQLETLRSKVAQLELQIASLNNEIE----RLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2305 EQLNEVIEKLQQELANIGQK-TLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQ 2383
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2384 ELFSLKRERESMEKI----------QSIPGKSVNMAIDDMSKDK-----------PELEVVLTEDALKSLENQTYLKSfE 2442
Cdd:TIGR02168  490 RLDSLERLQENLEGFsegvkallknQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQ-N 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2443 ENGKGSIINLETRLLQLESTVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEkVAAALVSQIQLEAvqEY 2522
Cdd:TIGR02168  569 ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD-LDNALELAKKLRP--GY 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2523 AKFCQDNQTISSE------PERTNIQNLNQLRE-DESGSNISALTLRISELESQLVEMHTSLILGKEQVEIAEKNVLEKE 2595
Cdd:TIGR02168  646 RIVTLDGDLVRPGgvitggSAKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2596 KKLLELQKLLEGNEKKQGGKERKRSPQDFEVLKTTtelfhsNEESGFLNELEALRAESVATKAQLTGYKEKTEKLQGELL 2675
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELE------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799

                          650       660       670
                   ....*....|....*....|....*....|...
gi 1622925520 2676 IKETNMASLQKDLSQVRDHLAEAKEKLSILEKE 2708
Cdd:TIGR02168  800 ALREALDELRAELTLLNEEAANLRERLESLERR 832
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1951-2715 2.28e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 2.28e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1951 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEeQVSRFIEL-EQEKNAELMDLRQQNQALEKQLEKmrkfLDEQAI 2029
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAE-KAERYKELkAELRELELALLVLRLEELREELEE----LQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2030 DREHERDVFQQEIQKLEQQLKVVPRFQPISEhqtREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 2109
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELE---EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2110 ELEQALLVSADTFQKVEDRKQfgaveakpelSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLE 2189
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLE----------ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2190 IQKKEST---TRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQhvlfgkfaqiIQEKEVEIDQLNEQIMKLQQQLKIT 2266
Cdd:TIGR02168  397 SLNNEIErleARLERLEDRRERLQQEIEELLKKLEEAELKELQAE----------LEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2267 TDNkvIEEKNELIRDLETQIECLmsdqecvkRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMV 2346
Cdd:TIGR02168  467 REE--LEEAEQALDAAERELAQL--------QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2347 IAEKLALE---QQVETTNEEMTF-TKNILKETNFkmNQLTQELFSLKRERE----SMEKIQSIPGksVNMAIDDMSKDKP 2418
Cdd:TIGR02168  537 AAIEAALGgrlQAVVVENLNAAKkAIAFLKQNEL--GRVTFLPLDSIKGTEiqgnDREILKNIEG--FLGVAKDLVKFDP 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2419 ELEVVLtEDAL------KSLENQTYLKSfEENGKGSIINLETRLL-----------QLESTVRAKDLELTQCYKQIKDMQ 2481
Cdd:TIGR02168  613 KLRKAL-SYLLggvlvvDDLDNALELAK-KLRPGYRIVTLDGDLVrpggvitggsaKTNSSILERRREIEELEEKIEELE 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2482 EQ---GQSEIEVLQKKILNLQKILEEKVAAALVSQIQLEAVQEYAKFcqdnqtissepERTNIQNLNQLREDESGsNISA 2558
Cdd:TIGR02168  691 EKiaeLEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR-----------LEAEVEQLEERIAQLSK-ELTE 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2559 LTLRISELESQLVEMHTSLILGKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQGGKERKRSPQDFEVLKTTTELFHSNE 2638
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622925520 2639 ESGFLNE-LEALRAESVATKAQLTGYKEKTEKLQGELLIKETNMASLQKDLSQVRDHLAEAKEKLSILEKEDKTAVQE 2715
Cdd:TIGR02168  839 RLEDLEEqIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRE 916
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 195-988 5.61e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 72.31  E-value: 5.61e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  195 EFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLrnsthsSTAADLLQAKQQIRTHQ 274
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQL------KEKLELEEEYLLYLDYL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  275 QQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKvyEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTA 354
Cdd:pfam02463  233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEE--EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKV 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  355 ADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGT-VEELQKRNHKDSQFETDIVQRMEQETQRKLEQL 433
Cdd:pfam02463  311 DDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEeEEELEKLQEKLEQLEEELLAKKKLESERLSSAA 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  434 RAELDEMYGQQIVQMKQELIRQHVSQMEELKTRHKgemeNALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLK 513
Cdd:pfam02463  391 KLKEEELELKSEEEKEAQLLLELARQLEDLLKEEK----KEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  514 EELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKaeivSASESRKELELKHEAEV 593
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRII----SAHGRLGDLGVAVENYK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  594 TNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNE 673
Cdd:pfam02463  543 VAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRA 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  674 MSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIE 753
Cdd:pfam02463  623 KVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIK 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  754 LLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLifiDSIKSKSKDSVWEKEIEILTEENEDLK 833
Cdd:pfam02463  703 KKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  834 QQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKTK 913
Cdd:pfam02463  780 REKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERL 859

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  914 SSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKE 988
Cdd:pfam02463  860 EEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 158-986 1.86e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.92  E-value: 1.86e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  158 EMMESELAGKQHEIEELNRELEEmrvtygTEGLQQLQEFEAaikqRDGIItQLTANLQQARREKDeTMREFLELTEQSQ- 236
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNE------SNELHEKQKFYL----RQSVI-DLQTKLQEMQMERD-AMADIRRRESQSQe 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  237 ----KLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDftmqisflqekiKVYEMEQ 312
Cdd:pfam15921  142 dlrnQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGK------------KIYEHDS 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  313 DKKVENSNKEEIQEKetIIEELNTKIIEEEKKTLELKDKLTA-----ADKLLGELQEQVVQKNQEIKNMKLELTNSKQKE 387
Cdd:pfam15921  210 MSTMHFRSLGSAISK--ILRELDTEISYLKGRIFPVEDQLEAlksesQNKIELLLQQHQDRIEQLISEHEVEITGLTEKA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  388 RQSSEEIKQLMGTVEELQKRnhkdSQFETDIVQRMEQETQRKLEQLRAELDE---MYGQQIVQMKQELIRQHvSQMEELK 464
Cdd:pfam15921  288 SSARSQANSIQSQLEIIQEQ----ARNQNSMYMRQLSDLESTVSQLRSELREakrMYEDKIEELEKQLVLAN-SELTEAR 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  465 T------RHKGEMENALRSY-PNITVNEDQIKLMNvainELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEEL 537
Cdd:pfam15921  363 TerdqfsQESGNLDDQLQKLlADLHKREKELSLEK----EQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  538 SfSREQIQRARQTIAEQESklneaQKSLSTVEDLKAEIvsasESRKELELKHEAEVTNYKIKLEMLEKeknAVLDRMAES 617
Cdd:pfam15921  439 K-SECQGQMERQMAAIQGK-----NESLEKVSSLTAQL----ESTKEMLRKVVEELTAKKMTLESSER---TVSDLTASL 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  618 QEAElerlrtQLLFSHEEELSKLKEDLEIEhqinIEKLKdnlgiHYKQQIDGLQNemsqkietmqfekdnlitkqnqlil 697
Cdd:pfam15921  506 QEKE------RAIEATNAEITKLRSRVDLK----LQELQ-----HLKNEGDHLRN------------------------- 545

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  698 eisklkdlqqslVNSKSEEMTLQINELQKEIEILRQEEKEK----GTLEQEVQELQLKIELLEKQMKEKENDLQEKftql 773
Cdd:pfam15921  546 ------------VQTECEALKLQMAEKDKVIEILRQQIENMtqlvGQHGRTAGAMQVEKAQLEKEINDRRLELQEF---- 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  774 eaenSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSvwekeieilteenEDLKQQCIQLNEEIEKQRNTFSFA 853
Cdd:pfam15921  610 ----KILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAV-------------KDIKQERDQLLNEVKTSRNELNSL 672

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  854 EKNFEVNYQELQEEyacllkvKDDLEDSKNKQELEYKSKLKALNEELH-LQRINPTTVKTKSSVFDEDKTFVAETLEMG- 931
Cdd:pfam15921  673 SEDYEVLKRNFRNK-------SEEMETTTNKLKMQLKSAQSELEQTRNtLKSMEGSDGHAMKVAMGMQKQITAKRGQIDa 745

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  932 -----EVVEKDTTELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQE 986
Cdd:pfam15921  746 lqskiQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEK 805
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 309-856 3.51e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 69.66  E-value: 3.51e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  309 EMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKEr 388
Cdd:TIGR04523  132 QKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKI- 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  389 qssEEIKQLMGTVEELQKRNhkdSQFETDIvqrmeQETQRKLEQLRAELDEMYgQQIVQMKQElirqhvsQMEELKTRHK 468
Cdd:TIGR04523  211 ---QKNKSLESQISELKKQN---NQLKDNI-----EKKQQEINEKTTEISNTQ-TQLNQLKDE-------QNKIKKQLSE 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  469 GEMEnalrsypnITVNEDQIKLMNVAINELNIKLQDTNSQKE-----KLKEELGVILEEKCALQRQLEDLFEELSFSREQ 543
Cdd:TIGR04523  272 KQKE--------LEQNNKKIKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  544 IQRARQTIAEQESKLNEAQKSL----STVEDLKAEIVSASESRKELELKHEAEVTNYKI--KLEMLEKEKNAVLDRMAES 617
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELeekqNEIEKLKKENQSYKQEIKNLESQINDLESKIQNqeKLNQQKDEQIKKLQQEKEL 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  618 QEAELERLRTQLLFSHEEELSKLKEDLEIEHQI-NIEKLKDNLgihyKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLI 696
Cdd:TIGR04523  424 LEKEIERLKETIIKNNSEIKDLTNQDSVKELIIkNLDNTRESL----ETQLKVLSRSINKIKQNLEQKQKELKSKEKELK 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  697 LEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKgTLEQEVQELQ--LKIELLEKQMKEKendlQEKFTQLE 774
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS-DLEDELNKDDfeLKKENLEKEIDEK----NKEIEELK 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  775 AENSILKDEKKALEDMLKIHTPDNQEerLIFIDSIKSKSKDSVwEKEIEILTEENEDL--------------KQQCIQLN 840
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKD--LIKEIEEKEKKISSL-EKELEKAKKENEKLssiiknikskknklKQEVKQIK 651

                          570
                   ....*....|....*.
gi 1622925520  841 EEIEKQRNTFSFAEKN 856
Cdd:TIGR04523  652 ETIKEIRNKWPEIIKK 667
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1839-2412 7.16e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 7.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1839 RQKQEATESLKCQEDLRERLHEE-SRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLqel 1917
Cdd:COG1196    207 RQAEKAERYRELKEELKELEAELlLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL--- 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1918 eaeqQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQcQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQ 1997
Cdd:COG1196    284 ----EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA-ELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1998 EKNAELMDLRQQNQALEKQLEKMRKFLDEQAiDREHERDVFQQEIQKLEQQLKVVPRFQpisEHQTREVEQLTNHLKEKT 2077
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELL-EALRAAAELAAQLEELEEAEEALLERL---ERLEEELEELEEALAELE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2078 DKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEAKPELSLEVQLQAERDAIDRKE 2157
Cdd:COG1196    435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2158 KEI--------------------TNLEEQLEQFREELENKNEEVQQLHMQLEIQKKEST------TRLQELEQENKLFKD 2211
Cdd:COG1196    515 LLAglrglagavavligveaayeAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflplDKIRARAALAAALAR 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2212 DMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITT-DNKVIEEKNELIRDLETQIEclm 2290
Cdd:COG1196    595 GAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTlEGEGGSAGGSLTGGSRRELL--- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2291 SDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNI 2370
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1622925520 2371 LKE---TNFKMNQLTQELFSLKRERESMEKiqsipgksVNM-AIDD 2412
Cdd:COG1196    752 ALEelpEPPDLEELERELERLEREIEALGP--------VNLlAIEE 789
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 553-886 9.47e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.54  E-value: 9.47e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  553 EQESKLNEAQKSLSTVEDLKAEIvsasesRKELE-LKHEAEVTN-YKIKLEMLEKEKNAVLDRMAESQEAELERLRTQL- 629
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNEL------ERQLKsLERQAEKAErYKELKAELRELELALLVLRLEELREELEELQEELk 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  630 -----LFSHEEELSKLKEDLEiehQINIEKLKDNLGIHYKQQ----IDGLQNEMSQKIETMQFEKDNLITKQNQLILEI- 699
Cdd:TIGR02168  250 eaeeeLEELTAELQELEEKLE---ELRLEVSELEEEIEELQKelyaLANEISRLEQQKQILRERLANLERQLEELEAQLe 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  700 ---SKLKDLQQSLvnsksEEMTLQINELQKEIEILRQEEKEKgtlEQEVQELQLKIELLEKQM---KEKENDLQEKFTQL 773
Cdd:TIGR02168  327 eleSKLDELAEEL-----AELEEKLEELKEELESLEAELEEL---EAELEELESRLEELEEQLetlRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  774 EAENSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEIlteenEDLKQQCIQLNEEIEKQRNTFSFA 853
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL-----EELQEELERLEEALEELREELEEA 473

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1622925520  854 EKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 886
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSE 506
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 166-535 1.09e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.16  E-value: 1.09e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  166 GKQHEIEELNRELEEMrvtygtegLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQL 245
Cdd:TIGR02168  674 ERRREIEELEEKIEEL--------EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  246 QAsetlrnsTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDftmqisfLQEKIkvyemEQDKKVENSNKEEIQ 325
Cdd:TIGR02168  746 EE-------RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE-------LEAQI-----EQLKEELKALREALD 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  326 EKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQL----MGTV 401
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALlnerASLE 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  402 EELQKRNHKDSQFETDIvQRMEQEtQRKLEQLRAELDEMYGQqiVQMKQELIRQHVSQM-EELKTRHKGEMENALRSYPN 480
Cdd:TIGR02168  887 EALALLRSELEELSEEL-RELESK-RSELRRELEELREKLAQ--LELRLEGLEVRIDNLqERLSEEYSLTLEEAEALENK 962

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  481 ITVN----EDQIKLMNVAINEL-NIKLqDTNSQKEKLKEELGVILEEKCALQRQLEDLFE 535
Cdd:TIGR02168  963 IEDDeeeaRRRLKRLENKIKELgPVNL-AAIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1585-2362 2.27e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.39  E-value: 2.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1585 NEEQLEDMRQELVRQYQehqqatELLRQAhmRQMERQREDQEQLQE--------EIKRLNKQLAQngNENQGEAEEQTFK 1656
Cdd:TIGR02168  187 NLDRLEDILNELERQLK------SLERQA--EKAERYKELKAELRElelallvlRLEELREELEE--LQEELKEAEEELE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1657 EKELDRKPEHVPPEILSNERYALQKANNRLLKILLEVVKTTAAVEETIGRHVlgiLDRSSKSQSSASLIWRSEAEASVKS 1736
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR---ERLANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1737 CVHEEHTRVTDEsipsysgSDMPRNDINMWSKVTEEGTELSQRLVRsgfagTEIDPENEelvlniSSRLQAAVEKLLEAI 1816
Cdd:TIGR02168  334 ELAEELAELEEK-------LEELKEELESLEAELEELEAELEELES-----RLEELEEQ------LETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1817 SETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLreRLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEK 1896
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1897 TDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAG--PVEQQLLQETEKLMKEkLEVQCQAEK---VR 1971
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGilGVLSELISVDEGYEAA-IEAALGGRLqavVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1972 DDLQKQVKALEIDVEEQVSR--FIELEQEKNAELmdlrqqNQALEKQLEKMRKFLDeQAIDREHERDVFQQEIQKLEQQL 2049
Cdd:TIGR02168  553 ENLNAAKKAIAFLKQNELGRvtFLPLDSIKGTEI------QGNDREILKNIEGFLG-VAKDLVKFDPKLRKALSYLLGGV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2050 KVVPRFQ------PISEHQTREV----EQLTNH--LKEKTDKCSELLLSKeqlQRDIQERNEEIEKLEFRVRELEQALlv 2117
Cdd:TIGR02168  626 LVVDDLDnalelaKKLRPGYRIVtldgDLVRPGgvITGGSAKTNSSILER---RREIEELEEKIEELEEKIAELEKAL-- 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2118 sADTFQKVEDRKQFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTT 2197
Cdd:TIGR02168  701 -AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2198 RLQELEQENKLFKDDMEKLGLAIKESDAVSTQ--DQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNkvIEEK 2275
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAEltLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED--IESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2276 NELIRDLETQIECLMSDQECV---KRNREEEIEQLNEVIEKLQQELANIGQKtlvdAHSLPEEADSLKHQLDMVIAEKLA 2352
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALlneRASLEEALALLRSELEELSEELRELESK----RSELRRELEELREKLAQLELRLEG 933

                          810
                   ....*....|
gi 1622925520 2353 LEQQVETTNE 2362
Cdd:TIGR02168  934 LEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1585-2228 3.14e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.50  E-value: 3.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1585 NEEQLEDMRQELVRQYQE-HQQA------TELLRQAHMRQMERQREDQEQLQEEIKRLNKQLAQNGNENQGEAEEQTFKE 1657
Cdd:COG1196    187 NLERLEDILGELERQLEPlERQAekaeryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1658 KELDRkpehvppeilsnERYALQKANNRLLKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEAsvksc 1737
Cdd:COG1196    267 AELEE------------LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE----- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1738 vheehtrvtdesipsysgsdmprndinmwskvtEEGTELSQRLVRSGFAGTEIDPENEELVLNIsSRLQAAVEKLLEAIS 1817
Cdd:COG1196    330 ---------------------------------EELEELEEELEELEEELEEAEEELEEAEAEL-AEAEEALLEAEAELA 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1818 ETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKT 1897
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1898 DIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQ 1977
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAA 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1978 VKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEK----QLEKMRK-FLDEQAIDREHERDVFQQEIQKLEQQLKVV 2052
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatflPLDKIRArAALAAALARGAIGAAVDLVASDLREADARY 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2053 PRFQPISEHQTREVEQLTNHLKEKTdKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFG 2132
Cdd:COG1196    616 YVLGDTLLGRTLVAARLEAALRRAV-TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2133 AVEAKPELSLEVQLQAERDAIDRKEK-EITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKD 2211
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEElEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774

                          650       660
                   ....*....|....*....|.
gi 1622925520 2212 DMEKLG----LAIKESDAVST 2228
Cdd:COG1196    775 EIEALGpvnlLAIEEYEELEE 795
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 321-1255 7.08e-10

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 65.84  E-value: 7.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  321 KEEIQEKETIIEELNTKIIEEEK-------KTLELKDKLTAADKLLGELQEQ---VVQKNQEIK---NMKLELTN----- 382
Cdd:TIGR01612  557 KKLIHEIKKELEEENEDSIHLEKeikdlfdKYLEIDDEIIYINKLKLELKEKiknISDKNEYIKkaiDLKKIIENnnayi 636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  383 ---SKQKERQSSEEIK---QLMGTVE-ELQK---------RNHKDSQFETDIVQRMEQETqrKLEQLRAELDEMYgQQIV 446
Cdd:TIGR01612  637 delAKISPYQVPEHLKnkdKIYSTIKsELSKiyeddidalYNELSSIVKENAIDNTEDKA--KLDDLKSKIDKEY-DKIQ 713

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  447 QMKQELIRQHVSQME-----------ELKTRHKGEMENALrsypNITVNEDQIKLmnvaiNELNIKLQDTNSQKEKLKEE 515
Cdd:TIGR01612  714 NMETATVELHLSNIEnkknelldiivEIKKHIHGEINKDL----NKILEDFKNKE-----KELSNKINDYAKEKDELNKY 784

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  516 LGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTN 595
Cdd:TIGR01612  785 KSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEKIDS 864

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  596 YKIKL-EMLEKEKNAVLDRMAESQEAEL---ERLRTQLLFSHEEELSKLKEDLEIEHQINI-EKLKDNL-GIHYKQQIdg 669
Cdd:TIGR01612  865 EHEQFaELTNKIKAEISDDKLNDYEKKFndsKSLINEINKSIEEEYQNINTLKKVDEYIKIcENTKESIeKFHNKQNI-- 942

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  670 LQNEMSQKIETMQfeKDNLITK------QNQLILEISKL----KDLQQSLVNSKSEEMTLQINELQ------KEIEILRQ 733
Cdd:TIGR01612  943 LKEILNKNIDTIK--ESNLIEKsykdkfDNTLIDKINELdkafKDASLNDYEAKNNELIKYFNDLKanlgknKENMLYHQ 1020

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  734 -EEKEKGT--LEQEVQELQLKIELLEKQMKEKENDLQEkftqlEAENSILKDEKKALEDMLKihtpdNQEERLIFIDSIK 810
Cdd:TIGR01612 1021 fDEKEKATndIEQKIEDANKNIPNIEIAIHTSIYNIID-----EIEKEIGKNIELLNKEILE-----EAEINITNFNEIK 1090

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  811 SKSK-----DSVWEKEIEILTEENEdLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQ 885
Cdd:TIGR01612 1091 EKLKhynfdDFGKEENIKYADEINK-IKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPE 1169

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  886 ELEYKsklkalneelhlQRINPTTVKTKSSVFDEDKTFVAETLEmgevVEKDTTElmekLEVTKREKLELSQRLADL--- 962
Cdd:TIGR01612 1170 EIEKK------------IENIVTKIDKKKNIYDEIKKLLNEIAE----IEKDKTS----LEEVKGINLSYGKNLGKLfle 1229

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  963 --SEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIIINHNRAGNVqscdTQVSSLSDGVVTMTSRDAEGSVSKVNk 1040
Cdd:TIGR01612 1230 kiDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMET----FNISHDDDKDHHIISKKHDENISDIR- 1304

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1041 sfgEESKIMVEDKVSFENMTTGKESKQEQLildhlpsvtkesslraaqpSENDKLQKELNVLKSEQNDLRLQMEAQRIcl 1120
Cdd:TIGR01612 1305 ---EKSLKIIEDFSEESDINDIKKELQKNL-------------------LDAQKHNSDINLYLNEIANIYNILKLNKI-- 1360

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1121 slvySTHVDQVREYMeNEKDKALCSLKEELiSAQEEKIKELQKIHQLELQNTKTQETGDeGKPLHLLIGKLRKA----VS 1196
Cdd:TIGR01612 1361 ----KKIIDEVKEYT-KEIEENNKNIKDEL-DKSEKLIKKIKDDINLEECKSKIESTLD-DKDIDECIKKIKELknhiLS 1433

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1197 EECSyfLQTLCSVLGEYYTPALKCEVNAEDRENSGDYTSENE-DSELQDYRYEVQDFQEN 1255
Cdd:TIGR01612 1434 EESN--IDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKkDNATNDHDFNINELKEH 1491
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3046-3393 7.68e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 7.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3046 LSEIQALHAQMNGRKITLKREQENEKSSQELleyniqqkQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQ 3125
Cdd:COG1196    188 LERLEDILGELERQLEPLERQAEKAERYREL--------KEELKELEAELLLLKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3126 TKLELETtlkaqhkhlKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSE---ERDKEELEDLKF 3202
Cdd:COG1196    260 AELAELE---------AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEerlEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3203 SLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQ 3282
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3283 sndgtgqsrpslpseDLLKELQKQLEEKHSRIVELLNETEKyKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHE 3362
Cdd:COG1196    411 ---------------ALLERLERLEEELEELEEALAELEEE-EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1622925520 3363 LQSKVEDLQRQLEEKRQQVYKLDLEGQRLQG 3393
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
495-990 9.49e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 9.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  495 INELNIKLQDTNSQKEKL---KEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDL 571
Cdd:PRK03918   209 INEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSASESRKELElKHEAEVTNYKIKLEMLEKEKNAVLDRM--AESQEAELERLRtQLLFSHEEELSKLKEDLEIEHQ 649
Cdd:PRK03918   289 KEKAEEYIKLSEFYE-EYLDELREIEKRLSRLEEEINGIEERIkeLEEKEERLEELK-KKLKELEKRLEELEERHELYEE 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  650 I-----NIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL--QIN 722
Cdd:PRK03918   367 AkakkeELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgrELT 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  723 ELQKEiEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLqEKFTQLEAENSILkDEKKALEDMLKIHT-----PD 797
Cdd:PRK03918   447 EEHRK-ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL-KKESELIKLKELA-EQLKELEEKLKKYNleeleKK 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  798 NQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNE------EIEKQRNTFSF-AEKNFEVNYQELQE---E 867
Cdd:PRK03918   524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDEleeelaELLKELEELGFeSVEELEERLKELEPfynE 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  868 YACLLKVKDDLEDSKNKQELEyKSKLKALNEELhlQRINPTTVKTKSSVFDEDKTFVAETLEMgevVEKDTTELMEKLEV 947
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKL-EEELDKAFEEL--AETEKRLEELRKELEELEKKYSEEEYEE---LREEYLELSRELAG 677

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1622925520  948 TKREKLELSQRLADLS---EQLKQKHGEISFLNEEVKSLKQEKEQV 990
Cdd:PRK03918   678 LRAELEELEKRREEIKktlEKLKEELEEREKAKKELEKLEKALERV 723
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 508-792 1.01e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  508 QKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLstvedlkaEIVSASESRKELEL 587
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE--------YELLAELARLEQDI 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  588 KHEAE-VTNYKIKLEMLEKEKnAVLDRMAESQEAELERLRTQLlfshEEELSKLKEDLEIEHQInieklkdnlgihyKQQ 666
Cdd:COG1196    305 ARLEErRRELEERLEELEEEL-AELEEELEELEEELEELEEEL----EEAEEELEEAEAELAEA-------------EEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  667 IDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKS--EEMTLQINELQKEIEILRQEEKEKGTLEQE 744
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErlERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622925520  745 VQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILK---DEKKALEDMLK 792
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLeelAEAAARLLLLL 497
PTZ00121 PTZ00121
MAEBL; Provisional
 161-949 1.05e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.16  E-value: 1.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQI 240
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  241 --QFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDftmqisflqekikvYEMEQDKKVEN 318
Cdd:PTZ00121  1169 arKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA--------------KKAEAVKKAEE 1234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  319 SNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKnmkleltnsKQKERQSSEEIKQlm 398
Cdd:PTZ00121  1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKK---------KADEAKKAEEKKK-- 1303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  399 gtVEELQKRnhKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQ-QIVQMKQELIRQHVSQMEELKTRHKGEMENALRS 477
Cdd:PTZ00121  1304 --ADEAKKK--AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  478 YPNITVNEDQIKlmnvAINELNIKLQDTNSQKEKLKEELGvilEEKCAlqrqledlfEELSFSREQIQRARQTI--AEQE 555
Cdd:PTZ00121  1380 ADAAKKKAEEKK----KADEAKKKAEEDKKKADELKKAAA---AKKKA---------DEAKKKAEEKKKADEAKkkAEEA 1443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  556 SKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEvtnykiklemlEKEKNAVLDRMAESQEAELERLRTQllfshEE 635
Cdd:PTZ00121  1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAE-----------EAKKADEAKKKAEEAKKKADEAKKA-----AE 1507

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  636 ELSKLKEDLEIEHQINIEKLKdnlgihykqqidglQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Cdd:PTZ00121  1508 AKKKADEAKKAEEAKKADEAK--------------KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  716 EmtlQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHT 795
Cdd:PTZ00121  1574 E---DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  796 PDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKvK 875
Cdd:PTZ00121  1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEN-K 1729

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  876 DDLEDSKNKQELEYKSKLKALNEELHLQRInpTTVKTKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTK 949
Cdd:PTZ00121  1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKI--AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 3021-3320 1.17e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 1.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3021 QRIQEQGVEYQAAMEYLQKADRRSLLSEIQALHAQMNGRKITLKREQENEKSSQELLEYNIQQKQSQMLEMQVELSSMKD 3100
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3101 RATELQEQLSSEKMVVAELRSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQwALE 3180
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE-AEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3181 KEKAKLGHSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLESE 3260
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622925520 3261 KVRIREMSSTLDRERELHAQLQS--NDGTGQSRPSLPSEDLLKELQKQLEEKHSRIVELLNE 3320
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAalAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2039-2397 1.88e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 1.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2039 QQEIQKLEQQLKvvpRFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVS 2118
Cdd:TIGR02169  680 RERLEGLKRELS---SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2119 ADTFQKVEDRKQfgaveakpelSLEVQLQAERDAIDRKEKEItnLEEQLEQFREELENKNEEVQQLHMQL---EIQKKES 2195
Cdd:TIGR02169  757 KSELKELEARIE----------ELEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKLEEEVSRIEARLreiEQKLNRL 824

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2196 TTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLfGKFAQIIQEKEVEIDQLNEQIMKLQQQ-LKITTDNKVIEE 2274
Cdd:TIGR02169  825 TLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK-EELEEELEELEAALRDLESRLGDLKKErDELEAQLRELER 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2275 KnelIRDLETQIECLmsdqecvkrnrEEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADslkhqLDMVIAEKLALE 2354
Cdd:TIGR02169  904 K---IEELEAQIEKK-----------RKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-----LEDVQAELQRVE 964

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1622925520 2355 QQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKRERESMEK 2397
Cdd:TIGR02169  965 EEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 365-776 2.90e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 2.90e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  365 QVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKrnhkdsqfETDIVQRMEQETQRKLEQLRAELDEmygqq 444
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--------ELEQLRKELEELSRQISALRKDLAR----- 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  445 ivqmkqelIRQHVSQMEELKTRHKGEMENAlrsypnitvnEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKC 524
Cdd:TIGR02168  738 --------LEAEVEQLEERIAQLSKELTEL----------EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  525 ALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLstvEDLKAEIVSASESRKELelkhEAEVTNYKIKLEMLE 604
Cdd:TIGR02168  800 ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL---EDLEEQIEELSEDIESL----AAEIEELEELIEELE 872

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  605 KEKNAVLDRMAESQEAeLERLRTQLLFSHEEELSKLKEDLEIEHQinIEKLKDNLGiHYKQQIDGLQNEMSQKIETM--- 681
Cdd:TIGR02168  873 SELEALLNERASLEEA-LALLRSELEELSEELRELESKRSELRRE--LEELREKLA-QLELRLEGLEVRIDNLQERLsee 948

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  682 -QFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTlqINELQkeIEILRQEEKEKGTLEQEVQELQLKIELLEKQM- 759
Cdd:TIGR02168  949 ySLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP--VNLAA--IEEYEELKERYDFLTAQKEDLTEAKETLEEAIe 1024

                          410       420
                   ....*....|....*....|
gi 1622925520  760 ---KEKENDLQEKFTQLEAE 776
Cdd:TIGR02168 1025 eidREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 508-999 4.45e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  508 QKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSL----STVEDLKAEIVSASESRK 583
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalaNEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  584 ELELKHEAevtnYKIKLEMLEKEKNAVLDRMAEsQEAELERLRTQLLfSHEEELSKLKEDLEIEHQINIEKlkdnlgihy 663
Cdd:TIGR02168  313 NLERQLEE----LEAQLEELESKLDELAEELAE-LEEKLEELKEELE-SLEAELEELEAELEELESRLEEL--------- 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  664 KQQIDGLQNEMSQKIETMQfekdnliTKQNQLILEISKLKDLQQSLVNSKSE----EMTLQINELQKEIEILRQEEKEKG 739
Cdd:TIGR02168  378 EEQLETLRSKVAQLELQIA-------SLNNEIERLEARLERLEDRRERLQQEieelLKKLEEAELKELQAELEELEEELE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  740 TLEQEVQELQLKIELLEKQMKEKENDLQekftQLEAENSILKDEKKALEDMLKIHTPDNQEERLIF-------------I 806
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALD----AAERELAQLQARLDSLERLQENLEGFSEGVKALLknqsglsgilgvlS 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  807 DSIKSKSKdsvWEKEIEI--------LTEENEDLKQQCIQLNEEIEKQRNTF----SFAEKNFEVNYQELQEEYACLLKV 874
Cdd:TIGR02168  527 ELISVDEG---YEAAIEAalggrlqaVVVENLNAAKKAIAFLKQNELGRVTFlpldSIKGTEIQGNDREILKNIEGFLGV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  875 KDDLEDSKNKQEL-------------EYKSKLKALNEELHLQRI--------------NPTTVKTKSSVFdEDKTFVAET 927
Cdd:TIGR02168  604 AKDLVKFDPKLRKalsyllggvlvvdDLDNALELAKKLRPGYRIvtldgdlvrpggviTGGSAKTNSSIL-ERRREIEEL 682

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  928 LEMGEVVEKDTTELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEI 999
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
284-784 4.54e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 4.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  284 LEDYQKKKEDFTMQISFLQEKIKVYE--MEQDKKVEN---SNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKL 358
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEkfIKRTENIEElikEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  359 ---LGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFET-----DIVQRMEQETQRKL 430
Cdd:PRK03918   237 keeIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyEEYLDELREIEKRL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  431 EQLRAELDEMYGQ-QIVQMKQELIRQHVSQMEELKtRHKGEMENALRSYPNITVNEDQIKlmnvainelNIKLQDTNSQK 509
Cdd:PRK03918   317 SRLEEEINGIEERiKELEEKEERLEELKKKLKELE-KRLEELEERHELYEEAKAKKEELE---------RLKKRLTGLTP 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  510 EKLKEELGVILEEKcalqrqlEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIvsASESRKELELKH 589
Cdd:PRK03918   387 EKLEKELEELEKAK-------EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGREL--TEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  590 EAEVTNYKIKLEMLEKEKNAVLDRMAE-----SQEAELERLRT--QLLFSHEEELSKL-KEDLEIEHQiNIEKLKDNLgI 661
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRElekvlKKESELIKLKElaEQLKELEEKLKKYnLEELEKKAE-EYEKLKEKL-I 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  662 HYKQQIDGLQNEMSqKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQ---KEIEILRQEEKEK 738
Cdd:PRK03918   536 KLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyNEYLELKDAEKEL 614

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1622925520  739 GTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEK 784
Cdd:PRK03918   615 EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE 660
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
160-660 6.31e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 6.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  160 MESELAGKQHEIEELNRELEEMRVTygTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQ 239
Cdd:PRK03918   212 ISSELPELREELEKLEKEVKELEEL--KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  240 IQFQQLQASETLRNSTHSS------TAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQD 313
Cdd:PRK03918   290 EKAEEYIKLSEFYEEYLDElreiekRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  314 KKVensNKEEIQEKETI--IEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSS 391
Cdd:PRK03918   370 KKE---ELERLKKRLTGltPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELT 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  392 EEIKqlmgtvEELQKRNHKdsqfETDIVQRMEQETQRKLEQLRAELDEMygQQIVQMKQELIRQH--VSQMEELKTRHKG 469
Cdd:PRK03918   447 EEHR------KELLEEYTA----ELKRIEKELKEIEEKERKLRKELREL--EKVLKKESELIKLKelAEQLKELEEKLKK 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  470 ----EMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDL-FEELSFSREQI 544
Cdd:PRK03918   515 ynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgFESVEELEERL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  545 QRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKheaevtnyKIKLEMLEKEKNAVLDRMAESQEAELER 624
Cdd:PRK03918   595 KELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAET--------EKRLEELRKELEELEKKYSEEEYEELRE 666

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1622925520  625 LRTQL---LFSHEEELSKLKEDLEiEHQINIEKLKDNLG 660
Cdd:PRK03918   667 EYLELsreLAGLRAELEELEKRRE-EIKKTLEKLKEELE 704
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 425-792 7.05e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 7.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  425 ETQRKLEQLRAELDEMYGQ-QIVQMKQELIRQhvsQMEELKT-RHKGEMENALRSypnitvnedqiKLMNVAINELNIKL 502
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENiERLDLIIDEKRQ---QLERLRReREKAERYQALLK-----------EKREYEGYELLKEK 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  503 QDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELsfsrEQIQRARQTIAEQESKL--NEAQKSLSTVEDLKAEIVSA-- 578
Cdd:TIGR02169  233 EALERQKEAIERQLASLEEELEKLTEEISELEKRL----EEIEQLLEELNKKIKDLgeEEQLRVKEKIGELEAEIASLer 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  579 SESRKELELKH-EAEVTNYKIKLEMLEKEKNAvLDRMAESQEAELERLRTQLLfSHEEELSKLK---EDLEIEHQINIEK 654
Cdd:TIGR02169  309 SIAEKERELEDaEERLAKLEAEIDKLLAEIEE-LEREIEEERKRRDKLTEEYA-ELKEELEDLRaelEEVDKEFAETRDE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  655 LKDnlgihYKQQIDGLQNEMsqkiETMQFEKDNLITKQNQLILEIS----KLKDLQQSLVNSKSEEMTLQInELQKEIEI 730
Cdd:TIGR02169  387 LKD-----YREKLEKLKREI----NELKRELDRLQEELQRLSEELAdlnaAIAGIEAKINELEEEKEDKAL-EIKKQEWK 456

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  731 LRQEEKEKGTLEQEVQELQLKIELLEKQMKEkendLQEKFTQLEAENSILKDE---KKALEDMLK 792
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSK----LQRELAEAEAQARASEERvrgGRAVEEVLK 517
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 267-1075 7.22e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 62.38  E-value: 7.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  267 KQQIRTHQQQLEEQDHLLEDYQKKKEDFtmqISFLQEKIKVYEMEQDKKVENSNKEEIQEK-ETIIEELNTK--IIEEEK 343
Cdd:TIGR01612 1117 KDDIKNLDQKIDHHIKALEEIKKKSENY---IDEIKAQINDLEDVADKAISNDDPEEIEKKiENIVTKIDKKknIYDEIK 1193

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  344 KTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKerQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Cdd:TIGR01612 1194 KLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKK--KSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMD 1271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  424 QETQRKLEQLRAELDEMY-------GQQIVQMKQELIR--QHVSQMEELKTRHKGEMENALRSYPNitvNEDQIKLMNVA 494
Cdd:TIGR01612 1272 IKAEMETFNISHDDDKDHhiiskkhDENISDIREKSLKiiEDFSEESDINDIKKELQKNLLDAQKH---NSDINLYLNEI 1348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  495 INELNI-KLQDTNSQKEKLKEELGVILEEKcalqrqlEDLFEELSFSREQIQRARQTIAEQESKlneaQKSLSTVE--DL 571
Cdd:TIGR01612 1349 ANIYNIlKLNKIKKIIDEVKEYTKEIEENN-------KNIKDELDKSEKLIKKIKDDINLEECK----SKIESTLDdkDI 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSASESRKELeLKHEAEVTNYKIKLEmlEKEKNAVLD----RMAESQEAELERLRTQLLFS-HEEELSKLKEDLEI 646
Cdd:TIGR01612 1418 DECIKKIKELKNHI-LSEESNIDTYFKNAD--ENNENVLLLfkniEMADNKSQHILKIKKDNATNdHDFNINELKEHIDK 1494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  647 EHQINIEKLKDNLGI--------HYKQQIDGLQNEMSQKIETMQFEKDNliTKQNQLILEISKLKDlQQSLVNSKSEEmt 718
Cdd:TIGR01612 1495 SKGCKDEADKNAKAIeknkelfeQYKKDVTELLNKYSALAIKNKFAKTK--KDSEIIIKEIKDAHK-KFILEAEKSEQ-- 1569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  719 lQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQM------KEKENDLQEKFTQLEAENSILKDEKKALEdmLK 792
Cdd:TIGR01612 1570 -KIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFlkisdiKKKINDCLKETESIEKKISSFSIDSQDTE--LK 1646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  793 iHTPDNQEERLIFIDSIKSKSKDSvwekeieilteenEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYAcll 872
Cdd:TIGR01612 1647 -ENGDNLNSLQEFLESLKDQKKNI-------------EDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIA--- 1709

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  873 kvkddledSKNKQELEYKSKLkalneelhlqrINPTTVKTKSSVFDEDktfvAETLEMGEVVEKDTTELMEKLEvtkrEK 952
Cdd:TIGR01612 1710 --------IANKEEIESIKEL-----------IEPTIENLISSFNTND----LEGIDPNEKLEEYNTEIGDIYE----EF 1762

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  953 LELSQRLADLSEQLKQ--------KHGEISFLNEEVKSLKQEKEQVL----LRCRELEIIINHNRagnvqscdtqvSSLS 1020
Cdd:TIGR01612 1763 IELYNIIAGCLETVSKepitydeiKNTRINAQNEFLKIIEIEKKSKSylddIEAKEFDRIINHFK-----------KKLD 1831

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520 1021 DGVVTMTSRdaegsVSKVNKSFGEESKimvedkvSFENMttgKESKQEQLILDHL 1075
Cdd:TIGR01612 1832 HVNDKFTKE-----YSKINEGFDDISK-------SIENV---KNSTDENLLFDIL 1871
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1997-2225 7.65e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.93  E-value: 7.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1997 QEKNAELMDLRQQNQALEKQLEKMRKfldeqaidrehERDVFQQEIQKLEQQLKVvprfqpisehQTREVEQLTNHLKEK 2076
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKK-----------EEKALLKQLAALERRIAA----------LARRIRALEQELAAL 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2077 TDKCSELLLSKEQLQRDIQERNEEIEKlefRVRELEQ-------ALLVSADTFQKVEDRKQ-FGAVEAkpelslevQLQA 2148
Cdd:COG4942     82 EAELAELEKEIAELRAELEAQKEELAE---LLRALYRlgrqpplALLLSPEDFLDAVRRLQyLKYLAP--------ARRE 150

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520 2149 ERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDA 2225
Cdd:COG4942    151 QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 330-1002 1.05e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  330 IIEELNTKIIEEEKKTLELK-------DKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVE 402
Cdd:TIGR04523   27 IANKQDTEEKQLEKKLKTIKnelknkeKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLS 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  403 ELqkrnhkDSQFETDIVQRMEQETQ-RKLEQLRAELDEmygqQIVQMKQELIRQHvSQMEELKTRHKgEMENALRSYpni 481
Cdd:TIGR04523  107 KI------NSEIKNDKEQKNKLEVElNKLEKQKKENKK----NIDKFLTEIKKKE-KELEKLNNKYN-DLKKQKEEL--- 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  482 tvnEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVI---LEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKL 558
Cdd:TIGR04523  172 ---ENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLkkkIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  559 NEAQKSLSTVEDLKAEIVSaSESRKELELKH--------EAEVTNYKIKLEMLEKEKNAVLDRMA----ESQEAELERLR 626
Cdd:TIGR04523  249 SNTQTQLNQLKDEQNKIKK-QLSEKQKELEQnnkkikelEKQLNQLKSEISDLNNQKEQDWNKELkselKNQEKKLEEIQ 327

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  627 TQLLFShEEELSKLKEDLEiehqiNIEKLKDNLGIHyKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLkdlq 706
Cdd:TIGR04523  328 NQISQN-NKIISQLNEQIS-----QLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDL---- 396

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  707 qslvNSKSEEMTLQINELQKEIEILrqeEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKA 786
Cdd:TIGR04523  397 ----ESKIQNQEKLNQQKDEQIKKL---QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  787 LEDMLKIhtpdnqeerlifIDSIKSKSKDSVWE-----KEIEILTEENEDLKQQCIQLNEEIEKQRNTfsfaEKNFEVNY 861
Cdd:TIGR04523  470 LKVLSRS------------INKIKQNLEQKQKElkskeKELKKLNEEKKELEEKVKDLTKKISSLKEK----IEKLESEK 533

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  862 QELQEEYACLLKVKDDLEDSKNKQELEykSKLKALNEELHLQRINPTTVKTKSSVFDED-KTFVAETLEMGEVVEKDTT- 939
Cdd:TIGR04523  534 KEKESKISDLEDELNKDDFELKKENLE--KEIDEKNKEIEELKQTQKSLKKKQEEKQELiDQKEKEKKDLIKEIEEKEKk 611

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  940 --ELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIIIN 1002
Cdd:TIGR04523  612 isSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKID 676
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 555-1163 1.20e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  555 ESKLNEAQKSLSTVEDLKAEIvsasesRKELE-LKHEAEVTN--YKIKLEMLEKEKNAVLDRMaESQEAELERLRTQLLf 631
Cdd:COG1196    178 ERKLEATEENLERLEDILGEL------ERQLEpLERQAEKAEryRELKEELKELEAELLLLKL-RELEAELEELEAELE- 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  632 SHEEELSKLKEDLEiEHQINIEKLKdnlgihykQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLvn 711
Cdd:COG1196    250 ELEAELEELEAELA-ELEAELEELR--------LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL-- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  712 sksEEMTLQINELQKEIEILRQE----EKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENS-ILKDEKKA 786
Cdd:COG1196    319 ---EELEEELAELEEELEELEEEleelEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEeLLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  787 LEDMLKIHTPDNQEERLIfIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNtfsfAEKNFEVNYQELQE 866
Cdd:COG1196    396 AELAAQLEELEEAEEALL-ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE----EEEALLELLAELLE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  867 EYACLLKVKDDLEDSKNKQELEYKSKLKAlnEELHLQRINPTTVKTKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLE 946
Cdd:COG1196    471 EAALLEAALAELLEELAEAAARLLLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  947 VTKRekLELSQRLADLSEQLKQ-KHGEISFL-----------NEEVKSLKQEKEQVLLRCRELEIIINHNRAGNVQSCDT 1014
Cdd:COG1196    549 QNIV--VEDDEVAAAAIEYLKAaKAGRATFLpldkiraraalAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1015 QVSSLSD-GVVTMTSRDAEGSVSKVNKSFGEESKIMVEDKVSFENMTTGKESKQEQLILDHLPSVTKESSLRAAQPSEND 1093
Cdd:COG1196    627 LVAARLEaALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE 706

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1094 KLQKELNVLKSEQNDLRLQMEAQRicLSLVYSTHVDQVREYMENEKDKALCSLKEELISAQEEKIKELQK 1163
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEEQL--EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774
PTZ00121 PTZ00121
MAEBL; Provisional
 215-945 1.42e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 1.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  215 QQARREKDETMREFLELTEQSQ-------KLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQ-QQLEEQDHLLED 286
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARmahfarrQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEaKKKAEEAKKADE 1319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  287 YQKKKEDFTMQISFLQEKikvyeMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQ--E 364
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKK-----AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKkaD 1394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  365 QVVQKNQEIKNmKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQ 444
Cdd:PTZ00121  1395 EAKKKAEEDKK-KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  445 IVQMKQELIRQhvsqMEELKtrhKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKc 524
Cdd:PTZ00121  1474 EAKKKAEEAKK----ADEAK---KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK- 1545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  525 alqRQLEDLFEElsfsrEQIQRARQTIAEQESKLNEAQKSLSTvedLKAEIVSASESRKELELKHEAEvTNYKIKLEMLE 604
Cdd:PTZ00121  1546 ---KKADELKKA-----EELKKAEEKKKAEEAKKAEEDKNMAL---RKAEEAKKAEEARIEEVMKLYE-EEKKMKAEEAK 1613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  605 KEKNAVLdRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKlkdnlgihyKQQIDGLQNEMSQKIETMQFE 684
Cdd:PTZ00121  1614 KAEEAKI-KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK---------AAEEAKKAEEDKKKAEEAKKA 1683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  685 KDNLITKQNQLILEISKLKdlqqslvnsKSEEMTLQINELQKEIEILRQEEKEKGT----LEQEVQELQLKIELLEKQMK 760
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAK---------KAEELKKKEAEEKKKAEELKKAEEENKIkaeeAKKEAEEDKKKAEEAKKDEE 1754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  761 EKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSV-----------WEKEIEIlTEEN 829
Cdd:PTZ00121  1755 EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIeggkegnlvinDSKEMED-SAIK 1833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  830 EDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQElqeeyACLLKVKDDLEDskNKQELEYKSKLKALNEELHLQRINPTT 909
Cdd:PTZ00121  1834 EVADSKNMQLEEADAFEKHKFNKNNENGEDGNKE-----ADFNKEKDLKED--DEEEIEEADEIEKIDKDDIEREIPNNN 1906

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1622925520  910 VKTKSSVFDEDKtfvaetLEMGEVVEKDTTELMEKL 945
Cdd:PTZ00121  1907 MAGKNNDIIDDK------LDKDEYIKRDAEETREEI 1936
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 304-857 1.50e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 60.89  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  304 KIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNS 383
Cdd:pfam05483  102 KQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREET 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  384 KQKERQSSEEIKQLMGTVEELQKRN-------HKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQqiVQMKQELIRQH 456
Cdd:pfam05483  182 RQVYMDLNNNIEKMILAFEELRVQAenarlemHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQ--ITEKENKMKDL 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  457 VSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEE 536
Cdd:pfam05483  260 TFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEE 339

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  537 LSFSREQ----IQRARQTIAEQESKLNEAQKSLSTVEDlKAEIVSASESRKELELKHEAEVTNYKiKLEMLEKEKNAVLD 612
Cdd:pfam05483  340 LNKAKAAhsfvVTEFEATTCSLEELLRTEQQRLEKNED-QLKIITMELQKKSSELEEMTKFKNNK-EVELEELKKILAED 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  613 RMAESQEAELERLRTQLLFSHEEELSKL----KEDLEIEHQINIEKLKDNlgiHYKQQIDGLQNEMSQ---KIETMQFEK 685
Cdd:pfam05483  418 EKLLDEKKQFEKIAEELKGKEQELIFLLqareKEIHDLEIQLTAIKTSEE---HYLKEVEDLKTELEKeklKNIELTAHC 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  686 DNLITKQNQLILEIS----KLKDLQQSLVNSKSEE--MTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKIELLEKQ 758
Cdd:pfam05483  495 DKLLLENKELTQEASdmtlELKKHQEDIINCKKQEerMLKQIENLEEKEMNLRDElESVREEFIQKGDEVKCKLDKSEEN 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  759 MKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQ 838
Cdd:pfam05483  575 ARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEE 654

                          570
                   ....*....|....*....
gi 1622925520  839 LNEEIEKQRNTFSFAEKNF 857
Cdd:pfam05483  655 IIDNYQKEIEDKKISEEKL 673
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 190-998 1.52e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 1.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  190 LQQLQEFEAAIKQRDGIITQLTANLQQARREKDETmrefleltEQSQKLQIQFQQLQASETLRnsthsstaadllqakqQ 269
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKA--------ERYQALLKEKREYEGYELLK----------------E 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  270 IRTHQQQLEEQDHLLEDYQKKKEDFTMQISflqekikvyemeqdkkvenSNKEEIQEKETIIEELNTKIIEE-EKKTLEL 348
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEELEKLTEEIS-------------------ELEKRLEEIEQLLEELNKKIKDLgEEEQLRV 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  349 KDKLtaadkllGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRnhkdsqfetdivqrmEQETQR 428
Cdd:TIGR02169  293 KEKI-------GELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE---------------IEEERK 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  429 KLEQLRAELDEmygqqivqmKQELIRQHVSQMEELKTRHKgemenalrsypnitvnedqiklmnvainELNIKLQDTNSQ 508
Cdd:TIGR02169  351 RRDKLTEEYAE---------LKEELEDLRAELEEVDKEFA----------------------------ETRDELKDYREK 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  509 KEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELK 588
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  589 HEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLF------------------------------------- 631
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLkasiqgvhgtvaqlgsvgeryataievaagnrlnnvv 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  632 -------------------------------SHEEELSKLKEDLEIEHQIN------------------------IEKLK 656
Cdd:TIGR02169  554 veddavakeaiellkrrkagratflplnkmrDERRDLSILSEDGVIGFAVDlvefdpkyepafkyvfgdtlvvedIEAAR 633

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  657 DNLGIHYKQQIDG---------------------LQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLvNSKSE 715
Cdd:TIGR02169  634 RLMGKYRMVTLEGelfeksgamtggsraprggilFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDEL-SQELS 712

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  716 EMTLQINELQKEIEIL-RQEEKEKGTLEQ---EVQELQLKIELLEKQMKEKENDLQEKFTQLEAensiLKDEKKALEDML 791
Cdd:TIGR02169  713 DASRKIGEIEKEIEQLeQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHK----LEEALNDLEARL 788

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  792 KIHTPDN--------------QEERLIFIDSIKSKS--KDSVWEKEIEILTEENEDLKQQCIQLNEEIE---KQRNTFSF 852
Cdd:TIGR02169  789 SHSRIPEiqaelskleeevsrIEARLREIEQKLNRLtlEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKEELEE 868

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  853 AEKNFEVNYQELQEEYACLLKVKDDLEdsknKQELEYKSKLKALNEELHLQRINPTTVKTK-SSVFDEDKTFVAETLEMG 931
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELE----AQLRELERKIEELEAQIEKKRKRLSELKAKlEALEEELSEIEDPKGEDE 944

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520  932 EVVEKDTTElmEKLEVTKREKLELSQRLADLS----EQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELE 998
Cdd:TIGR02169  945 EIPEEELSL--EDVQAELQRVEEEIRALEPVNmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYE 1013
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1835-2207 2.06e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 2.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1835 RESFRQKQEATESLK-----CQEDLRE---RLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQE 1906
Cdd:TIGR02169  673 PAELQRLRERLEGLKrelssLQSELRRienRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1907 LLCASNRLQELEAEQqqiqeerELLSRQKEAMKAEAGPVEQQLLQEteklmkeklevqcQAEKVRDDLQKqvkaLEIDVE 1986
Cdd:TIGR02169  753 IENVKSELKELEARI-------EELEEDLHKLEEALNDLEARLSHS-------------RIPEIQAELSK----LEEEVS 808

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1987 EQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKfLDEQAIDREHERDVFQQEIQKLEQQLKvvprfqpisEHQTrEV 2066
Cdd:TIGR02169  809 RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRID-LKEQIKSIEKEIENLNGKKEELEEELE---------ELEA-AL 877

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2067 EQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEAKPELSLEvQL 2146
Cdd:TIGR02169  878 RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLE-DV 956

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520 2147 QAERdaiDRKEKEITNLEE----QLEQFREELENKNeEVQQLHMQLEIQKKESTTRLQELEQENK 2207
Cdd:TIGR02169  957 QAEL---QRVEEEIRALEPvnmlAIQEYEEVLKRLD-ELKEKRAKLEEERKAILERIEEYEKKKR 1017
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1836-2401 2.27e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.42  E-value: 2.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1836 ESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLcasnRLQ 1915
Cdd:TIGR04523  125 ELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLL----KLE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1916 ELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKV------RDDLQKQVKALEIDVEEQV 1989
Cdd:TIGR04523  201 LLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLnqlkdeQNKIKKQLSEKQKELEQNN 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1990 SRFIELE---QEKNAELMDLRQQ-NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRfqpISEHQTRE 2065
Cdd:TIGR04523  281 KKIKELEkqlNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK---ELTNSESE 357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2066 VEQLTNHLKEKTDKCselllskEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfgaVEAKPELSLEVQ 2145
Cdd:TIGR04523  358 NSEKQRELEEKQNEI-------EKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIK---KLQQEKELLEKE 427

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2146 LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLgLAIKESDA 2225
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL-KKLNEEKK 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2226 VSTQDQHVLFGKFAQIIQ----------EKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQEc 2295
Cdd:TIGR04523  507 ELEEKVKDLTKKISSLKEkieklesekkEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQE- 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2296 vkrNREEEIEQLNEVIEKLQQELANIGQKTLvdahSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETN 2375
Cdd:TIGR04523  586 ---EKQELIDQKEKEKKDLIKEIEEKEKKIS----SLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIR 658

                          570       580
                   ....*....|....*....|....*.
gi 1622925520 2376 FKMNQLtqelfsLKRERESMEKIQSI 2401
Cdd:TIGR04523  659 NKWPEI------IKKIKESKTKIDDI 678
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 302-1173 4.90e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 4.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  302 QEKIKVYEMEQDKKVENSNKEEIQ-EKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLEL 380
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIiDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  381 TNSKQKERQSSeeiKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMygQQIVQMKQELIRQ---HV 457
Cdd:pfam02463  246 LRDEQEEIESS---KQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEL--LKLERRKVDDEEKlkeSE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  458 SQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGvilEEKCALQRQLEDLFEEL 537
Cdd:pfam02463  321 KEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK---LESERLSSAAKLKEEEL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  538 SFsREQIQRARQTIAEQESKLNEAQKSLSTVEdlkAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Cdd:pfam02463  398 EL-KSEEEKEAQLLLELARQLEDLLKEEKKEE---LEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  618 QEAELErlrTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQ-NQLI 696
Cdd:pfam02463  474 LKETQL---VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAIsTAVI 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  697 LEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAE 776
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILK 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  777 NSILKDEKKALEDMLKIHTPDNQEERLIFidsIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKN 856
Cdd:pfam02463  631 DTELTKLKESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQR 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  857 FEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSKLKALNEELHLQRINPTTVKTKSSVFDEDKTFVAETLEMGEV 933
Cdd:pfam02463  708 EKEELKKLKLEAEELLADRVQEAQDKINEElklLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  934 VEKDTTELMEKLEVTKREKLELSQRLADLSEQLkQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIIINHNRAGNVQSCD 1013
Cdd:pfam02463  788 VEEEKEEKLKAQEEELRALEEELKEEAELLEEE-QLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1014 TQVSSLSDGVVTMTSRDAEgSVSKVNKSFGEESKIMVEDKVSFENMTTGKESKQEQLILDHLPSVTKESSLRAAQPSEND 1093
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1094 KLQKELNVLKSEQNDLRLQMEAQRICLSLVystHVDQVREYMENEKDKAlcSLKEELISAQEEKIKELQKIHQLELQNTK 1173
Cdd:pfam02463  946 DEKEKEENNKEEEEERNKRLLLAKEELGKV---NLMAIEEFEEKEERYN--KDELEKERLEEEKKKLIRAIIEETCQRLK 1020
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 170-810 5.27e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.21  E-value: 5.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  170 EIEELNRELEEMRVTYgtEGLQQLQEFEAAIKQRDGIITQLTANLQQAR---------REKDETMREFLELTEQS----- 235
Cdd:TIGR00618  227 ELKHLREALQQTQQSH--AYLTQKREAQEEQLKKQQLLKQLRARIEELRaqeavleetQERINRARKAAPLAAHIkavtq 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  236 --QKLQIQFQQLQASETLRNSTHSSTAAdlLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDftMQISFLQEKIKVYEMEQD 313
Cdd:TIGR00618  305 ieQQAQRIHTELQSKMRSRAKLLMKRAA--HVKQQSSIEEQRRLLQTLHSQEIHIRDAHE--VATSIREISCQQHTLTQH 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  314 KKVENSNKEEIQEKETIIEELNTKIIEEEKKTL-------ELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSK-- 384
Cdd:TIGR00618  381 IHTLQQQKTTLTQKLQSLCKELDILQREQATIDtrtsafrDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKih 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  385 -QKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMY-----GQQIVQMKQELIRQHVS 458
Cdd:TIGR00618  461 lQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQdidnpGPLTRRMQRGEQTYAQL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  459 QMEELKTRHKG--EMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEK----CALQRQLED 532
Cdd:TIGR00618  541 ETSEEDVYHQLtsERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEdmlaCEQHALLRK 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  533 LFEELSfsrEQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLD 612
Cdd:TIGR00618  621 LQPEQD---LQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  613 RMAESQEAelerlrTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHyKQQIDGLQNEMSQKIETMQFEKDNLITKQ 692
Cdd:TIGR00618  698 MLAQCQTL------LRELETHIEEYDREFNEIENASSSLGSDLAAREDAL-NQSLKELMHQARTVLKARTEAHFNNNEEV 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  693 NQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQ 772
Cdd:TIGR00618  771 TAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQ 850

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1622925520  773 LEAENSILKDEKKALEDMLKIHTpdnQEERLIFIDSIK 810
Cdd:TIGR00618  851 LLKYEECSKQLAQLTQEQAKIIQ---LSDKLNGINQIK 885
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1804-2184 5.67e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 5.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1804 RLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYA 1883
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1884 DEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEV 1963
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1964 QcQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKfLDEQAIDREHERDVFQQEIQ 2043
Cdd:TIGR02168  841 E-DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELE 918

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2044 KLEQQLkvvprfqpiSEHQTREvEQLTNHLKEKTDKCSELL-LSKEQLQRDIQERNEEIEKLEFRVRELEQAL------- 2115
Cdd:TIGR02168  919 ELREKL---------AQLELRL-EGLEVRIDNLQERLSEEYsLTLEEAEALENKIEDDEEEARRRLKRLENKIkelgpvn 988

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2116 LVSADTFQKVEDRKQFgaveakpelsLEVQLQAERDAIDRKEKEITNL-EEQLEQFREELENKNEEVQQL 2184
Cdd:TIGR02168  989 LAAIEEYEELKERYDF----------LTAQKEDLTEAKETLEEAIEEIdREARERFKDTFDQVNENFQRV 1048
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1993-2506 5.93e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.88  E-value: 5.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1993 IELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQaidreherdvfQQEIQKLEQQLKVvprfqpISEHQTREVEQLTNH 2072
Cdd:TIGR04523  210 IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEK-----------TTEISNTQTQLNQ------LKDEQNKIKKQLSEK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2073 LKEktdkcselllsKEQLQRDIQERNEEIEKLEFRVRELEQallvsadtfQKVEDRKQfgavEAKPEL-SLEVQLQAERD 2151
Cdd:TIGR04523  273 QKE-----------LEQNNKKIKELEKQLNQLKSEISDLNN---------QKEQDWNK----ELKSELkNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2152 AIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEiqkkESTTRLQELEQENKLFKDDMEKLGLAIKESDAvSTQDQ 2231
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELE----EKQNEIEKLKKENQSYKQEIKNLESQINDLES-KIQNQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2232 HVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQlkITTDNKVIEEKNELIRDLETQIECLmsdqECVKRNREEEIEQLNEVI 2311
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKET--IIKNNSEIKDLTNQDSVKELIIKNL----DNTRESLETQLKVLSRSI 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2312 EKLQQELANIGQktlvdahslpeEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKRE 2391
Cdd:TIGR04523  478 NKIKQNLEQKQK-----------ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2392 RESMEkiqsipgksvnmaiDDMSKDKPELEVVLTEDALKSL-ENQTYLKSFEENGKGSIINLETRLLQLESTVRAKDLEL 2470
Cdd:TIGR04523  547 LNKDD--------------FELKKENLEKEIDEKNKEIEELkQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKI 612

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1622925520 2471 TQCYKQIKDMQEQgQSEIEVLQKKILNLQKILEEKV 2506
Cdd:TIGR04523  613 SSLEKELEKAKKE-NEKLSSIIKNIKSKKNKLKQEV 647
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2063-2713 5.98e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.88  E-value: 5.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2063 TREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEdrkqfgaveaKPELSL 2142
Cdd:TIGR04523   39 EKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLN----------SDLSKI 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2143 EVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEI---QKKESTTRLQELEQENKLFKDDMEKLGLA 2219
Cdd:TIGR04523  109 NSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKlnnKYNDLKKQKEELENELNLLEKEKLNIQKN 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2220 IKESDAVSTQDQHVLFgkfaqIIQEKEVEIDQLNEQIMKLQQQLKITTDNkvIEEKNELIRDLETQIECLMSDQECVKRN 2299
Cdd:TIGR04523  189 IDKIKNKLLKLELLLS-----NLKKKIQKNKSLESQISELKKQNNQLKDN--IEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2300 REEEIEQLNEVIEKLQQELANIGQKTlVDAHSLPEEADSLKHQLDMVIAEKlaLEQQVETTNEEMTFTKNILKETNFKMN 2379
Cdd:TIGR04523  262 QNKIKKQLSEKQKELEQNNKKIKELE-KQLNQLKSEISDLNNQKEQDWNKE--LKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2380 QLTQELFSLKRERESMEkiqsipgkSVNMAIDDMSKDKPELEVVLTEDALKSLENQTYLKSFEENGKGSIINLETRLLQL 2459
Cdd:TIGR04523  339 QLNEQISQLKKELTNSE--------SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2460 ESTVRAKDLELTQCYKQIKDMQEQ---GQSEIEVLQKKILNLQKILEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEP 2536
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETiikNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKE 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2537 ERTNIQNLNQLREDES---------GSNISALTLRISELESQLVEMHTSLILGKEQVEIAEKNVLEKEKKLLELQKLLEG 2607
Cdd:TIGR04523  491 LKSKEKELKKLNEEKKeleekvkdlTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEI 570

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2608 NEKKQGGKERKRSPQDFEVLKTTTElfhsNEESGFLNELEALRAESVATKAQLTGYKEKTEKLQGELLIKETNMASLQKD 2687
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKE----KEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646

                          650       660
                   ....*....|....*....|....*.
gi 1622925520 2688 LSQVRDHLAEAKEKLSILEKEDKTAV 2713
Cdd:TIGR04523  647 VKQIKETIKEIRNKWPEIIKKIKESK 672
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 574-1361 7.35e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.83  E-value: 7.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  574 EIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQ----EAELERLRTQLLFSHEEELSKLKEDLEIEHQ 649
Cdd:pfam02463  145 EIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIidleELKLQELKLKEQAKKALEYYQLKEKLELEEE 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  650 INIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDN---LITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 726
Cdd:pfam02463  225 YLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKeeeKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLK 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  727 EIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSIlKDEKKALEDMLKIHTPDNQEERLIFI 806
Cdd:pfam02463  305 LERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEE-EEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  807 DSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKnKQE 886
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELK-LLK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  887 LEYKSKLKALNEELHLQRINPTTVKTKSSVFDEDKTFVAETlemgEVVEKDTTELMEKLEVTKREKLELSQRLADLSEQL 966
Cdd:pfam02463  463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES----KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  967 -KQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIIINHNRAGNVQSCDTQVSSLSDGVVTMTSRDAEGSVSKVNKSFGEE 1045
Cdd:pfam02463  539 eNYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1046 SKIMVEDKVSFENMTTGKE---SKQEQLILDHLPSVTKESSLRAAQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLSL 1122
Cdd:pfam02463  619 DKRAKVVEGILKDTELTKLkesAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQ 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1123 VYSTHVDQVREYMENEKDKALCSLKEELISAQEEKIKELQKIHQlelqntktQETGDEGKPLHLLIGKLRKAVSEECSYF 1202
Cdd:pfam02463  699 LEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLK--------QKIDEEEEEEEKSRLKKEEKEEEKSELS 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1203 LQTLCSVLGEYYTPALKCEVNAEDRENSGDyTSENEDSELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSkiwg 1282
Cdd:pfam02463  771 LKEKELAEEREKTEKLKVEEEKEEKLKAQE-EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE---- 845

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520 1283 qQTDGMKLEFGEENLPKEETKFLSIHSQMTSLEDSDVNHKSKLSSLQHLEKTEQLEEQVQELESLISSLQQQLKETEQS 1361
Cdd:pfam02463  846 -QKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 505-835 1.29e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 57.83  E-value: 1.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  505 TNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSR---EQIQRARQTiaEQESKLNEAQKSLSTVEDLKAEIVsASES 581
Cdd:pfam17380  264 TMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERlrqEKEEKAREV--ERRRKLEEAEKARQAEMDRQAAIY-AEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  582 RKELELKHEAE---VTNYKIKLEMLEKEKNAV-LDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKD 657
Cdd:pfam17380  341 RMAMERERELErirQEERKRELERIRQEEIAMeISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKV 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  658 NLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKdlQQSLVNSKSEEMTLQINELQKEIEILRQE--E 735
Cdd:pfam17380  421 EMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLR--QQEEERKRKKLELEKEKRDRKRAEEQRRKilE 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  736 KEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILK----DEKKALEDMLKIHTpdnqEERlifidsiks 811
Cdd:pfam17380  499 KELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKqqemEERRRIQEQMRKAT----EER--------- 565

                          330       340
                   ....*....|....*....|....
gi 1622925520  812 kSKDSVWEKEIEILTEENEDLKQQ 835
Cdd:pfam17380  566 -SRLEAMEREREMMRQIVESEKAR 588
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3083-3401 1.74e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3083 QKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLN 3162
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3163 DTLASEQKKSRELQWALEKEKAKLGHSEERdKEELEDLKFSLESQkqrnlqlnllleqqkqlLDESQQKIESQRMLYDAQ 3242
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEE-LAEAEAEIEELEAQ-----------------IEQLKEELKALREALDEL 808

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3243 LSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSNDGTGQSrpslpSEDLLKELQKQLEEKHSRIVELLNEte 3322
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES-----LAAEIEELEELIEELESELEALLNE-- 881

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520 3323 kykldslqtRQQMEKDRQVHRKTLQTEQEantegqkKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQ 3401
Cdd:TIGR02168  882 ---------RASLEEALALLRSELEELSE-------ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1947-2181 2.37e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 2.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1947 QQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQE---KNAELMDLRQQNQALEKQLEKMRKF 2023
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQElaaLEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2024 LDEQ--AIDREHERD-----VFQQEIQKLEQQLKVvprFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQE 2096
Cdd:COG4942    106 LAELlrALYRLGRQPplallLSPEDFLDAVRRLQY---LKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2097 RNEEIEKLEFRVRELEQALlvsadtfqkvedrkqfgaveakpeLSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELEN 2176
Cdd:COG4942    183 LEEERAALEALKAERQKLL------------------------ARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ....*
gi 1622925520 2177 KNEEV 2181
Cdd:COG4942    239 AAERT 243
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 157-440 2.67e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 2.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  157 LEMMESELAGKQHEIEELNRELEEMRVtYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQ 236
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEA-EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  237 KLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQIsflqekikvyemeqdkkv 316
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL------------------ 875

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  317 eNSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQkerQSSEEIKQ 396
Cdd:TIGR02168  876 -EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE---RLSEEYSL 951

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1622925520  397 LMGTVEELQKRNHKDsqfetdivqrmEQETQRKLEQLRAELDEM 440
Cdd:TIGR02168  952 TLEEAEALENKIEDD-----------EEEARRRLKRLENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 528-900 3.37e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 56.61  E-value: 3.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  528 RQLEDLFEELSFSREQIQRARQTIAEQESKLneaqkslstvEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEK 607
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQL----------ERLRREREKAERYQALLKEKREYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  608 NAVLDRMAEsQEAELERLrTQLLFSHEEELSKLKEDLEiEHQINIEKLKDNLGIHYKQQIDGLQNEMSQ---KIETMQFE 684
Cdd:TIGR02169  240 EAIERQLAS-LEEELEKL-TEEISELEKRLEEIEQLLE-ELNKKIKDLGEEEQLRVKEKIGELEAEIASlerSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  685 KDNLITKQNQLILEISKLKdlqqslvnskseemtLQINELQKEIEilrQEEKEKGTLEQEVQELQLKIELLEKQMKEKEN 764
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLL---------------AEIEELEREIE---EERKRRDKLTEEYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  765 DLQEKFTQLeaensilKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIE 844
Cdd:TIGR02169  379 EFAETRDEL-------KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622925520  845 KQRntfsfaeknfevnyQELQEEYACLLKVKDDLEDSKNKQElEYKSKLKALNEEL 900
Cdd:TIGR02169  452 KQE--------------WKLEQLAADLSKYEQELYDLKEEYD-RVEKELSKLQREL 492
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 161-860 3.55e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.52  E-value: 3.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEM---RVTYGTEGLQQLQEFEAAIKQRDGIIT---QLTANLQQARREKDETMREFLELTEQ 234
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELeikREAEEEEEEELEKLQEKLEQLEEELLAkkkLESERLSSAAKLKEEELELKSEEEKE 406

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  235 SQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDK 314
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  315 KVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVV-QKNQEIKNMKLELTNSKQKERQSSEE 393
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEnYKVAISTAVIVEVSATADEVEERQKL 566

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  394 IKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVqmKQELIRQHVSQMEELKTRHKGEMEN 473
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDD--KRAKVVEGILKDTELTKLKESAKAK 644

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  474 ALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKcaLQRQLEDLFEELSFSREQIQRARQTIAE 553
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEI--LRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  554 QESKLNEAQ-KSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFS 632
Cdd:pfam02463  723 LADRVQEAQdKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  633 HEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNS 712
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQ 882

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  713 KSEEMTLqinELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDE----KKALE 788
Cdd:pfam02463  883 KLKDELE---SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKeennKEEEE 959

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  789 DMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVN 860
Cdd:pfam02463  960 ERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINK 1031
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2087-2401 6.84e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 6.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2087 KEQLQRDIQERNEEIEKLEFRVRELEQALlvsadtfQKVEDRKqfgaveAKPELSLEVQLQAERDAIDRKEKEITNLEEQ 2166
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQL-------ERLRRER------EKAERYQALLKEKREYEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2167 LEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKfaqiIQEKE 2246
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS----IAEKE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2247 VEIDQLNEQIMKLQQQlkittdnkvIEEKNELIRDLETQIEclmsDQECVKRNREEEIEQLNEVIEKLQQELANIGQK-- 2324
Cdd:TIGR02169  315 RELEDAEERLAKLEAE---------IDKLLAEIEELEREIE----EERKRRDKLTEEYAELKEELEDLRAELEEVDKEfa 381

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520 2325 TLVDAH-SLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKRE-RESMEKIQSI 2401
Cdd:TIGR02169  382 ETRDELkDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEiKKQEWKLEQL 460
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 92-1174 6.97e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.83  E-value: 6.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520   92 ITSHEQVFSVeLESEISTT-ADDYSSEVNGCSFVMKTGKPTNLlrEEEFGVDDSYSEQGAQYSLTH---LEMMESELAGK 167
Cdd:TIGR01612  651 LKNKDKIYST-IKSELSKIyEDDIDALYNELSSIVKENAIDNT--EDKAKLDDLKSKIDKEYDKIQnmeTATVELHLSNI 727

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  168 QHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDgiiTQLTANLQQARREKDEtmrefleLTEQSQKLQIQFQQLQA 247
Cdd:TIGR01612  728 ENKKNELLDIIVEIKKHIHGEINKDLNKILEDFKNKE---KELSNKINDYAKEKDE-------LNKYKSKISEIKNHYND 797

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  248 SETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTmqisflqEKIKVYemeqdKKVENSNKEEIQEK 327
Cdd:TIGR01612  798 QINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFL-------NKVDKF-----INFENNCKEKIDSE 865

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  328 ETIIEELNTKIIEE--EKKTLELKDKLTAADKLLGELQEQVVQKNQEI-------------KNMKLELTNSKQKERQSSE 392
Cdd:TIGR01612  866 HEQFAELTNKIKAEisDDKLNDYEKKFNDSKSLINEINKSIEEEYQNIntlkkvdeyikicENTKESIEKFHNKQNILKE 945

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  393 EIKQLMGTVEE--LQKRNHKDsQFETDIVQRMeQETQRKLEQLRAELDEMYGQQIVQM-----------KQELIRQHVSQ 459
Cdd:TIGR01612  946 ILNKNIDTIKEsnLIEKSYKD-KFDNTLIDKI-NELDKAFKDASLNDYEAKNNELIKYfndlkanlgknKENMLYHQFDE 1023

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  460 MEELKTRHKGEMENALRSYPNITV--------------NE--DQIKLMNVAI-NELNIKLQDTNSQKEKLKEE--LGVIL 520
Cdd:TIGR01612 1024 KEKATNDIEQKIEDANKNIPNIEIaihtsiyniideieKEigKNIELLNKEIlEEAEINITNFNEIKEKLKHYnfDDFGK 1103

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  521 EEKCALQRQLEDLFEELSFSREQIQRARQTIAE----QESKLNEAQKSLSTVEDLKAEIVSaSESRKELELKHEAEVTNY 596
Cdd:TIGR01612 1104 EENIKYADEINKIKDDIKNLDQKIDHHIKALEEikkkSENYIDEIKAQINDLEDVADKAIS-NDDPEEIEKKIENIVTKI 1182

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  597 KIKLEMLEkEKNAVLDRMA--ESQEAELERLRTqLLFSHEEELSKL------KEDLEIEHQIN-IEKLKDNLGiHYKQQI 667
Cdd:TIGR01612 1183 DKKKNIYD-EIKKLLNEIAeiEKDKTSLEEVKG-INLSYGKNLGKLflekidEEKKKSEHMIKaMEAYIEDLD-EIKEKS 1259

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  668 DGLQNEM------SQKIETMQF----EKDNLITKQNQlILEISKLKDLQQSLVNSKSEEMtlQINELQKEIEI-LRQEEK 736
Cdd:TIGR01612 1260 PEIENEMgiemdiKAEMETFNIshddDKDHHIISKKH-DENISDIREKSLKIIEDFSEES--DINDIKKELQKnLLDAQK 1336

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  737 EKGTLEQEVQELQLKIELLE-KQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDnqeerlIFIDSIKSKSKD 815
Cdd:TIGR01612 1337 HNSDINLYLNEIANIYNILKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDD------INLEECKSKIES 1410

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  816 SVWEKEIEilteenedlkqQCIQlneEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE--LEYKSKL 893
Cdd:TIGR01612 1411 TLDDKDID-----------ECIK---KIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDN 1476

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  894 KALNEELHLQRINPTTVKTK--SSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEvtkreKLELSQRLADLSEQLKQKHG 971
Cdd:TIGR01612 1477 ATNDHDFNINELKEHIDKSKgcKDEADKNAKAIEKNKELFEQYKKDVTELLNKYS-----ALAIKNKFAKTKKDSEIIIK 1551

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  972 EISFLNEEVKSLKQEKEQVLLRCRELEIIINHNRAGNVQSCDTQVsslsdgvvtmtsrDAEGSVSKVNKSFGEESKImve 1051
Cdd:TIGR01612 1552 EIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAI-------------DIQLSLENFENKFLKISDI--- 1615

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1052 dKVSFENMTTGKESKQEQLilDHLPSVTKESSLRAAQPSENdKLQKELNVLKSEQNDLrlqmEAQRICLSlvystHVDQV 1131
Cdd:TIGR01612 1616 -KKKINDCLKETESIEKKI--SSFSIDSQDTELKENGDNLN-SLQEFLESLKDQKKNI----EDKKKELD-----ELDSE 1682

                         1130      1140      1150      1160
                   ....*....|....*....|....*....|....*....|...
gi 1622925520 1132 REYMENEKDKALCSLKEELIsaqeEKIKELQKIHQLELQNTKT 1174
Cdd:TIGR01612 1683 IEKIEIDVDQHKKNYEIGII----EKIKEIAIANKEEIESIKE 1721
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2087-2735 7.95e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 7.95e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2087 KEQLQRDIQERNEEIEKLEFRVRELEQallvsadtfqkVEDRKQFGAVEAKPELSLEVQ-LQAERDAI----DRKEKEIT 2161
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNE-----------LHEKQKFYLRQSVIDLQTKLQeMQMERDAMadirRRESQSQE 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2162 NLEEQLEQFREELEN----KNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGK 2237
Cdd:pfam15921  142 DLRNQLQNTVHELEAakclKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSA 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2238 FAQIIQEKEVEIDQLNEQIMKLQQQ---LKITTDNKVieekNELIRDLETQIECLMSDQE----------CVKRNREEEI 2304
Cdd:pfam15921  222 ISKILRELDTEISYLKGRIFPVEDQleaLKSESQNKI----ELLLQQHQDRIEQLISEHEveitgltekaSSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2305 EQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKL-ALEQQVETTNEEMTFTKNILKETNFKMNQLTQ 2383
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIeELEKQLVLANSELTEARTERDQFSQESGNLDD 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2384 ELFSL-----KRERE-SMEKIQ-----------SIPGKSVNMAIDDMSKDKPELEVVLTedALKS-LENQTYLKSFEENG 2445
Cdd:pfam15921  378 QLQKLladlhKREKElSLEKEQnkrlwdrdtgnSITIDHLRRELDDRNMEVQRLEALLK--AMKSeCQGQMERQMAAIQG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2446 KG-SIINLETRLLQLEST----------VRAKDLELTQCYKQIKDMQ----------EQGQSEIEVLQKKI-LNLQKILE 2503
Cdd:pfam15921  456 KNeSLEKVSSLTAQLESTkemlrkvveeLTAKKMTLESSERTVSDLTaslqekeraiEATNAEITKLRSRVdLKLQELQH 535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2504 EKVAAALVSQIQLEAVQEYAKFCQDNQTIssEPERTNIQNLNQLrEDESGSNISALTLRISELESQLVEMHTSL-----I 2578
Cdd:pfam15921  536 LKNEGDHLRNVQTECEALKLQMAEKDKVI--EILRQQIENMTQL-VGQHGRTAGAMQVEKAQLEKEINDRRLELqefkiL 612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2579 LGKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQGGKERKRSPQDF--EVLKTTTELFHSNEE-----SGFLNELEALRA 2651
Cdd:pfam15921  613 KDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLlnEVKTSRNELNSLSEDyevlkRNFRNKSEEMET 692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2652 ESVATKAQLTGYKEKTEKLQGELLIKETN-------MASLQKDLSQVRDHLAEAKEKLSILEKEDKTAvqeNKKACMFKP 2724
Cdd:pfam15921  693 TTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvAMGMQKQITAKRGQIDALQSKIQFLEEAMTNA---NKEKHFLKE 769

                          730
                   ....*....|.
gi 1622925520 2725 LPVKLSKSIAS 2735
Cdd:pfam15921  770 EKNKLSQELST 780
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 156-593 8.01e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 8.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  156 HLEMMESELAGKQHEIEELNRELEEMRVTYGT--EGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREfleLTE 233
Cdd:pfam15921  445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMlrKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE---ITK 521

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  234 QSQKLQIQFQQLQasetlrnstHSSTAADLLQ-AKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME- 311
Cdd:pfam15921  522 LRSRVDLKLQELQ---------HLKNEGDHLRnVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEk 592

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  312 -QDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQS 390
Cdd:pfam15921  593 aQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  391 SEEIkqlmgtveELQKRNHKDSQFE----TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHvsqmeelktr 466
Cdd:pfam15921  673 SEDY--------EVLKRNFRNKSEEmettTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK---------- 734

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  467 hkgemenalrsypNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQR 546
Cdd:pfam15921  735 -------------QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERR 801

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1622925520  547 ARQTIAEQESKLNEAQKSLSTVEDLkaeIVSASESRKELELKHEAEV 593
Cdd:pfam15921  802 LKEKVANMEVALDKASLQFAECQDI---IQRQEQESVRLKLQHTLDV 845
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1795-2284 8.94e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 55.51  E-value: 8.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1795 EELVLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMREsfrQKQEATESLKCQEDLRERLHEESRAREQLAVELSK 1874
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTE---RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQ 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1875 AEGVID---GYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 1951
Cdd:pfam15921  400 NKRLWDrdtGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRK 479

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1952 ETEKLMKEKLEVQCQAEKVRD---DLQKQVKALEidveeqvsrfieleqEKNAELMDLRQQnqaLEKQLEKMRKFLDEQa 2028
Cdd:pfam15921  480 VVEELTAKKMTLESSERTVSDltaSLQEKERAIE---------------ATNAEITKLRSR---VDLKLQELQHLKNEG- 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2029 idrEHERDVfQQEIQKLEQQLKVVPRFQPISEHQtreVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEF-- 2106
Cdd:pfam15921  541 ---DHLRNV-QTECEALKLQMAEKDKVIEILRQQ---IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIlk 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2107 -----RVRELEQAllVSADTFQKVEdrkqfgAVEAKPELSLEVQ-LQAERDAIDRKEK----EITNLEEQLEQFREELEN 2176
Cdd:pfam15921  614 dkkdaKIRELEAR--VSDLELEKVK------LVNAGSERLRAVKdIKQERDQLLNEVKtsrnELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2177 KNEEVQQLHMQLEIQKKESTTrlqELEQENKLFKDDMEKLGLAIKEsdAVSTQDQhvlfgkfaqiIQEKEVEIDQLNEQI 2256
Cdd:pfam15921  686 KSEEMETTTNKLKMQLKSAQS---ELEQTRNTLKSMEGSDGHAMKV--AMGMQKQ----------ITAKRGQIDALQSKI 750

                          490       500       510
                   ....*....|....*....|....*....|
gi 1622925520 2257 MKLQQQLKITTDNK--VIEEKNELIRDLET 2284
Cdd:pfam15921  751 QFLEEAMTNANKEKhfLKEEKNKLSQELST 780
PTZ00121 PTZ00121
MAEBL; Provisional
 216-797 9.59e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 9.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  216 QARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLE---EQDHLLEDYQKKKE 292
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKkkaEEAKKAEEAKKKAE 1467

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  293 dftmqisflqEKIKVYEMEqdKKVENSNKEEIQEKETiieELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQE 372
Cdd:PTZ00121  1468 ----------EAKKADEAK--KKAEEAKKADEAKKKA---EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE 1532

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  373 IKNMKlelTNSKQKERQSSEEIKQL--MGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 450
Cdd:PTZ00121  1533 AKKAD---EAKKAEEKKKADELKKAeeLKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  451 ELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQdtnSQKEKLKEElgvilEEKcalqRQL 530
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK---AAEEAKKAE-----EDK----KKA 1677

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  531 EDLFEELSFSREQIQRARQTiaEQESKLNEAQKSLSTVEDLKAEIVSASESRKEL---ELKHEAEVTNYKIKLEMLEKEK 607
Cdd:PTZ00121  1678 EEAKKAEEDEKKAAEALKKE--AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIkaeEAKKEAEEDKKKAEEAKKDEEE 1755

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  608 NAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDN 687
Cdd:PTZ00121  1756 KKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEV 1835

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  688 LITKQNQliLEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILR--QEEKEKGTLEQEVQELQLKIELLEKQMKEKEND 765
Cdd:PTZ00121  1836 ADSKNMQ--LEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEddEEEIEEADEIEKIDKDDIEREIPNNNMAGKNND 1913

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1622925520  766 LqeKFTQLEAENSILKDEKKALEDMLKIHTPD 797
Cdd:PTZ00121  1914 I--IDDKLDKDEYIKRDAEETREEIIKISKKD 1943
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 512-831 1.47e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 54.55  E-value: 1.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  512 LKEELGVILEekcALQR----QLEDLFEELSfsREQIQRARqtiaeqeSKLNEAQKSLSTVEDLKAEIVSASESRKELEL 587
Cdd:PRK05771    14 LKSYKDEVLE---ALHElgvvHIEDLKEELS--NERLRKLR-------SLLTKLSEALDKLRSYLPKLNPLREEKKKVSV 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  588 KHEAEVtnykikLEMLEKEKNAVLDRMaESQEAELERLRTQLlfsheEELSKLKEDLEIEHQINIEkLKDNLGIHYKQQI 667
Cdd:PRK05771    82 KSLEEL------IKDVEEELEKIEKEI-KELEEEISELENEI-----KELEQEIERLEPWGNFDLD-LSLLLGFKYVSVF 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  668 DGlqnemsqKIETMQFEKDNLITKQNQLIlEISKLKDLQQSLVNSKSEEMTLQINELqKEIEILRQEEKEKGTLEQEVQE 747
Cdd:PRK05771   149 VG-------TVPEDKLEELKLESDVENVE-YISTDKGYVYVVVVVLKELSDEVEEEL-KKLGFERLELEEEGTPSELIRE 219

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  748 LQLKIELLEKQMKEKENDLQEK-------FTQLEAENSILKDEKKALEDMLK------IH--TPDNQEERLifIDSIKSK 812
Cdd:PRK05771   220 IKEELEEIEKERESLLEELKELakkyleeLLALYEYLEIELERAEALSKFLKtdktfaIEgwVPEDRVKKL--KELIDKA 297

                          330
                   ....*....|....*....
gi 1622925520  813 SKDSVWEKEIEIlTEENED 831
Cdd:PRK05771   298 TGGSAYVEFVEP-DEEEEE 315
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1968-2504 1.52e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 1.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1968 EKVRDDLQKQVKALEiDVEEQVSRFIELEQEKNAELMDLRQQNQAlEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQ 2047
Cdd:PRK03918   144 DESREKVVRQILGLD-DYENAYKNLGEVIKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELRE 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2048 QLKVVprfqpisEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEqallvsadtfQKVED 2127
Cdd:PRK03918   222 ELEKL-------EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE----------EKVKE 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2128 RKQFGAvEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFRE---ELENKNEEVQqlhmQLEIQKKESTTRLQELEQ 2204
Cdd:PRK03918   285 LKELKE-KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEErikELEEKEERLE----ELKKKLKELEKRLEELEE 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2205 ENKLFKDDMEKLGlaikESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQqlKITTDNKVIEEKNELIRDLET 2284
Cdd:PRK03918   360 RHELYEEAKAKKE----ELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA--RIGELKKEIKELKKAIEELKK 433

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2285 qieclmSDQECVKRNREEEIEQLNEVIEKLQQELANIgQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQvETTNEEM 2364
Cdd:PRK03918   434 ------AKGKCPVCGRELTEEHRKELLEEYTAELKRI-EKELKEIEEKERKLRKELRELEKVLKKESELIKL-KELAEQL 505

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2365 TFTKNILKETNF-KMNQLTQELFSLKRERESMEKIQSIPGKSVNmAIDDMSKDKPELEVVL--TEDALKSLENQtylksF 2441
Cdd:PRK03918   506 KELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLdeLEEELAELLKE-----L 579

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622925520 2442 EENGKGSIINLETRLLQLESTVRaKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEE 2504
Cdd:PRK03918   580 EELGFESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKR 641
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 489-1198 1.64e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  489 KLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELsfsreqIQRARQTIAEQESKLNEAQKSLSTV 568
Cdd:pfam02463  218 KLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEK------LAQVLKENKEEEKEKKLQEEELKLL 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  569 EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEH 648
Cdd:pfam02463  292 AKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  649 QINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILeisKLKDLQQSLVNSKSEEMTLQINELQKEI 728
Cdd:pfam02463  372 EEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDL---LKEEKKEELEILEEEEESIELKQGKLTE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  729 EILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLIFIDS 808
Cdd:pfam02463  449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  809 IKSKSKDSVWEKE----IEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 884
Cdd:pfam02463  529 GRLGDLGVAVENYkvaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  885 QELEYK-------SKLKALNEELHLQRINPTTVKTKSSVFDEDKTFVAETLEMGEV---VEKDTTELMEKLEVTKREKLE 954
Cdd:pfam02463  609 DKATLEadeddkrAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVkasLSELTKELLEIQELQEKAESE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  955 LsQRLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIIINHNRAGNVQ--------------SCDTQVSSLS 1020
Cdd:pfam02463  689 L-AKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQkideeeeeeeksrlKKEEKEEEKS 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1021 DGVVTMTSRDAEGSVSKVNKSFGEESKIMVEDKVSFENMttgKESKQEQLILDHLPSVTKESSLRAAQPSENDKLQKELN 1100
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL---EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKE 844

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1101 VLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELISA--QEEKIKELQKIHQLELQNTKTQETG 1178
Cdd:pfam02463  845 EQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEekKELEEESQKLNLLEEKENEIEERIK 924

                          730       740
                   ....*....|....*....|
gi 1622925520 1179 DEGKPLHLLIGKLRKAVSEE 1198
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEE 944
PRK01156 PRK01156
chromosome segregation protein; Provisional
 267-847 1.98e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 54.14  E-value: 1.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  267 KQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTL 346
Cdd:PRK01156   189 EEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSME 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  347 ELKD-KLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKrnhKDSQFETDIVQRMEQe 425
Cdd:PRK01156   269 LEKNnYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIK---KLSVLQKDYNDYIKK- 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  426 tQRKLEQLRAELDEMYGQQI-VQMKQELIRQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIklmNVAINELNIKLQD 504
Cdd:PRK01156   345 -KSRYDDLNNQILELEGYEMdYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI---KKELNEINVKLQD 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  505 TNSQKEKLKEELGVILEEKCALQRQLEDLFEE-------LSFSREQIQRARQTIAEQESKLNEAQKSLST-VEDLKAEIV 576
Cdd:PRK01156   421 ISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgTTLGEEKSNHIINHYNEKKSRLEEKIREIEIeVKDIDEKIV 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  577 SASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELErlrtqllfsHEEELSKLKE-DLEIEHQINIEKL 655
Cdd:PRK01156   501 DLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDK---------YEEIKNRYKSlKLEDLDSKRTSWL 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  656 KDNLGIhykQQIDgLQNEMSQKIETMQFEKDnLITKQNQLILEISKLKDLQQSlvnskseemtlQINELQKEIEILRQEE 735
Cdd:PRK01156   572 NALAVI---SLID-IETNRSRSNEIKKQLND-LESRLQEIEIGFPDDKSYIDK-----------SIREIENEANNLNNKY 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  736 KEKGTLEQEVQELQLKIELLEKQ---MKEKENDLQEKFTQLEAENSILKDEKKALEDmlkihtpdnqeerlifidsikSK 812
Cdd:PRK01156   636 NEIQENKILIEKLRGKIDNYKKQiaeIDSIIPDLKEITSRINDIEDNLKKSRKALDD---------------------AK 694

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1622925520  813 SKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQR 847
Cdd:PRK01156   695 ANRARLESTIEILRTRINELSDRINDINETLESMK 729
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1972-2175 2.25e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 2.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1972 DDLQKQVKALEiDVEEQVSRFIELEQEKnAELMDLRQQNQALEKQLEkmRKFLDEQAIDREHERDVFQQEIQKLEQQLkv 2051
Cdd:COG4913    245 EDAREQIELLE-PIRELAERYAAARERL-AELEYLRAALRLWFAQRR--LELLEAELEELRAELARLEAELERLEARL-- 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2052 vprfqpisEHQTREVEQLTNHLKE-KTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQ 2130
Cdd:COG4913    319 --------DALREELDELEAQIRGnGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAA 390

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 2131 fGAVEAKPELS---------LEVQLQAERDAIDRKEKEITNLE-------EQLEQFREELE 2175
Cdd:COG4913    391 -ALLEALEEELealeealaeAEAALRDLRRELRELEAEIASLErrksnipARLLALRDALA 450
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
2088-2312 3.39e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 53.32  E-value: 3.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2088 EQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDrkqfgaveakpELSLevqLQAERDAIDRKEKEITNLEEQL 2167
Cdd:COG2433    409 TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLER-----------ELSE---ARSEERREIRKDREISRLDREI 474

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2168 EQFREELENKNEEVQQLHMQLEIQKkesttRLQELEQENKLF---------KDDMEKL--GLAIKESDAVSTQDQHVLFG 2236
Cdd:COG2433    475 ERLERELEEERERIEELKRKLERLK-----ELWKLEHSGELVpvkvvekftKEAIRRLeeEYGLKEGDVVYLRDASGAGR 549

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2237 KFAQIIQEKEVEIDQLNEQI-MKLQQQLK------ITTDNKVIEEKNEL----IRDLETQIECLMSDQEcvKRNREEEIE 2305
Cdd:COG2433    550 STAELLAEAGPRAVIVPGELsEAADEVLFeegipvLPAEDVTIQEVDDLavvdEEELEAAIEDWEERAE--ERRREKKAE 627


                   ....*..
gi 1622925520 2306 QLNEVIE 2312
Cdd:COG2433    628 MLERLIS 634
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 161-365 3.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEMRVTYgTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQI 240
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEE-KALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  241 QFQQlQASETLRNSTHSS-----TAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKK 315
Cdd:COG4942    105 ELAE-LLRALYRLGRQPPlalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  316 VENSNK--EEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQ 365
Cdd:COG4942    184 EEERAAleALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PTZ00121 PTZ00121
MAEBL; Provisional
 309-999 4.57e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 4.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  309 EMEQDKKVENSNKEEIQEKETIIEE---LNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKnmKLELTNSKQ 385
Cdd:PTZ00121  1078 DFDFDAKEDNRADEATEEAFGKAEEakkTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEAR--KAEDAKRVE 1155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  386 KERQSSEEIKQLMGTVEELQKRNHKDSQFETdiVQRMEQ----ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHVSQME 461
Cdd:PTZ00121  1156 IARKAEDARKAEEARKAEDAKKAEAARKAEE--VRKAEElrkaEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAE 1233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  462 ELKTRhkgemENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQ-RQLEDL--FEELS 538
Cdd:PTZ00121  1234 EAKKD-----AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEaKKAEEKkkADEAK 1308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  539 FSREQIQRARQT--IAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKH-EAEVTNYKIKLEMLEKEKNAVLDRMA 615
Cdd:PTZ00121  1309 KKAEEAKKADEAkkKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAaEEKAEAAEKKKEEAKKKADAAKKKAE 1388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  616 ESQEAELERLRTQLLFSHEEELSKLKEDLEI--EHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQfEKDNLITKQN 693
Cdd:PTZ00121  1389 EKKKADEAKKKAEEDKKKADELKKAAAAKKKadEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK-KAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  694 qlilEISKLKDLQQSLVNS-KSEEMTLQINELQKEIEILRQEEKEKGTLEqevqelqlkiELLEKQMKEKENDLQEKFTQ 772
Cdd:PTZ00121  1468 ----EAKKADEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKAD----------EAKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  773 LEAENSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSF 852
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK 1613

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  853 AEKNFEVNYQELQEEYacllKVKDDLEDSKNKQElEYKSKLKALNEELHLQRINPTTVKTKSsvfDEDKTfVAETLEMGE 932
Cdd:PTZ00121  1614 KAEEAKIKAEELKKAE----EEKKKVEQLKKKEA-EEKKKAEELKKAEEENKIKAAEEAKKA---EEDKK-KAEEAKKAE 1684

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520  933 VVEKDTTELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEI 999
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKK 1751
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1837-2112 4.60e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.82  E-value: 4.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1837 SFRQKQEATESLKcQEDLRERLHEESRA---REQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQEllcasNR 1913
Cdd:pfam17380  285 SERQQQEKFEKME-QERLRQEKEEKAREverRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE-----ER 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1914 LQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKL----------EVQCQAEKVRDDL----QKQVK 1979
Cdd:pfam17380  359 KRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKIleeerqrkiqQQKVEMEQIRAEQeearQREVR 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1980 ALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQK-----LEQQLKVVPR 2054
Cdd:pfam17380  439 RLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEErkqamIEEERKRKLL 518

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622925520 2055 FQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELE 2112
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMERERE 576
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
272-776 5.18e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 5.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  272 THQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQdkkvensnkEEIQEKETIIEELNTKIIEEEKKTLELKDK 351
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR---------EELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  352 LTAADKLLGEL-----------------QEQVVQKNQEIKNMKLELTNSKQKERQS----SEEIKQLMGTVEELQKRNHK 410
Cdd:PRK02224   281 VRDLRERLEELeeerddllaeaglddadAEAVEARREELEDRDEELRDRLEECRVAaqahNEEAESLREDADDLEERAEE 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  411 --------DSQFETDIVQRMEQETQrkLEQLRAELDEM---YGQQIVQMK--QELIRQHVSQMEELKTRHKgEMENALRS 477
Cdd:PRK02224   361 lreeaaelESELEEAREAVEDRREE--IEELEEEIEELrerFGDAPVDLGnaEDFLEELREERDELREREA-ELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  478 YPNiTVNEDQIKL---------MNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQR---QLEDLFE---ELSFSRE 542
Cdd:PRK02224   438 ARE-RVEEAEALLeagkcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEErleRAEDLVEaedRIERLEE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  543 QIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMaesqeAEL 622
Cdd:PRK02224   517 RREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERI-----ESL 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  623 ERLRTQL--LFSHEEELSKLKEDLEIEHQINIEKlKDNLGiHYKQQIDGLQNEMSQ-KIETMQFEKDNLITKQNQlilei 699
Cdd:PRK02224   592 ERIRTLLaaIADAEDEIERLREKREALAELNDER-RERLA-EKRERKRELEAEFDEaRIEEAREDKERAEEYLEQ----- 664

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520  700 sklkdlqqslVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKEnDLQEKFTQLEAE 776
Cdd:PRK02224   665 ----------VEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALEALYDEAE-ELESMYGDLRAE 730
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2088-2263 5.51e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.61  E-value: 5.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2088 EQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEAkpELSlevQLQAERDAIDRKEKEITNLEEQL 2167
Cdd:COG4913    620 AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAER--EIA---ELEAELERLDASSDDLAALEEQL 694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2168 EQFREELENKNEEVQQLhmQLEIQKKEST-TRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKE 2246
Cdd:COG4913    695 EELEAELEELEEELDEL--KGEIGRLEKElEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLE 772

                          170
                   ....*....|....*..
gi 1622925520 2247 VEIDQLNEQIMKLQQQL 2263
Cdd:COG4913    773 ERIDALRARLNRAEEEL 789
PTZ00121 PTZ00121
MAEBL; Provisional
 3029-3401 5.59e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.84  E-value: 5.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3029 EYQAAMEYLQKADRRSLLSEIQALHAQMNGRKITLKREQENEKSSQELLEYNIQQKQSQMLEMQVElssMKDRATELQEQ 3108
Cdd:PTZ00121  1376 AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE---EAKKADEAKKK 1452

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3109 lSSEKMVVAELRSELAQTKLELETTLKAQH-KHLKELEAFRLEVKDKTDEVHllndTLASEQKKSRELQWALEKEKAKLG 3187
Cdd:PTZ00121  1453 -AEEAKKAEEAKKKAEEAKKADEAKKKAEEaKKADEAKKKAEEAKKKADEAK----KAAEAKKKADEAKKAEEAKKADEA 1527

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3188 HSEErDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEhgrnlelqvLLESEKVRIREM 3267
Cdd:PTZ00121  1528 KKAE-EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE---------AKKAEEARIEEV 1597

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3268 SSTLDRERELHAQL-----QSNDGTGQSRPSLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVH 3342
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEakkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA 1677

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 3343 RKTLQTEQEAN--TEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQ 3401
Cdd:PTZ00121  1678 EEAKKAEEDEKkaAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE 1738
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 352-586 6.93e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 6.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  352 LTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRnhkdsqfetdivqrmEQETQRKLE 431
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR---------------IRALEQELA 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  432 QLRAELDEMyGQQIVQMKQELIRQHvsqmEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEK 511
Cdd:COG4942     80 ALEAELAEL-EKEIAELRAELEAQK----EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE 154

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  512 LKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLstvEDLKAEIVSASESRKELE 586
Cdd:COG4942    155 LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKEL---AELAAELAELQQEAEELE 226
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2018-2216 7.04e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 50.31  E-value: 7.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2018 EKMRKFLDEQAIDreherdvfqQEIQKLEQQLKVVPRfqpisehqtrEVEQLTNHLKEKTDKCSELLLSKEQLQRDIQER 2097
Cdd:COG1579      4 EDLRALLDLQELD---------SELDRLEHRLKELPA----------ELAELEDELAALEARLEAAKTELEDLEKEIKRL 64

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2098 NEEIEKLEFRVRELEQALlvsadtfQKVEDRKQFGAveakpelsLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENK 2177
Cdd:COG1579     65 ELEIEEVEARIKKYEEQL-------GNVRNNKEYEA--------LQKEIESLKRRISDLEDEILELMERIEELEEELAEL 129

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1622925520 2178 NEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2216
Cdd:COG1579    130 EAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 191-407 7.43e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 7.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  191 QQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQI 270
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  271 RTHQQQLEEQdhlLEDYQKKKEDFTMQISFLQEKIK--VYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 348
Cdd:COG4942    100 EAQKEELAEL---LRALYRLGRQPPLALLLSPEDFLdaVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520  349 KDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR 407
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1810-2590 8.01e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 8.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1810 EKLLEAISETSSQLEHakvtQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYADEKTLF 1889
Cdd:pfam02463  173 EALKKLIEETENLAEL----IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1890 ERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELlsrQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEK 1969
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELK---LLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1970 VRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQL 2049
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2050 KVvprfQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRK 2129
Cdd:pfam02463  406 EA----QLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2130 QfgavEAKPELSLEVQLQAERDAIDRKEkeitnleeqleqfrEELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLF 2209
Cdd:pfam02463  482 L----QEQLELLLSRQKLEERSQKESKA--------------RSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKV 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2210 KDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKI-TTDNKVIEEKNELIRDLETQIEC 2288
Cdd:pfam02463  544 AISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIdPILNLAQLDKATLEADEDDKRAK 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2289 LMSDQE-CVKRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFT 2367
Cdd:pfam02463  624 VVEGILkDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2368 KNILKETNFKMNQLTQELFSLKRERESMEKIQSIPgKSVNMAIDDMSKDKPELEVVLTEDALKSLENQTYLKSFEENGKG 2447
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEEL-KLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREK 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2448 SIINLETRllQLESTVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEKVAAALVSQIQLEAVQEYAKFCQ 2527
Cdd:pfam02463  783 TEKLKVEE--EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLE 860

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622925520 2528 DNQTISSEPERTNIQNLNQLREDESGSNISALTLRISELESQLVEMHTSLILGKEQVEIAEKN 2590
Cdd:pfam02463  861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1796-2364 8.05e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 8.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1796 ELVL---NISSRLQAAVEkLLEAISETSSQLEHAK--VTQTELMRESFRQKQEATESLKCQEDLRERLHeesRAREQLAV 1870
Cdd:COG4913    215 EYMLeepDTFEAADALVE-HFDDLERAHEALEDAReqIELLEPIRELAERYAAARERLAELEYLRAALR---LWFAQRRL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1871 ELSKAEgvIDGYADEKTLFERQIQEKTDIIDRLEQELlcasnrlQELEaeqqqiqeerellsrqkEAMKAEAGPVEQQLL 1950
Cdd:COG4913    291 ELLEAE--LEELRAELARLEAELERLEARLDALREEL-------DELE-----------------AQIRGNGGDRLEQLE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1951 QETEKLMKEKLEVqcqaEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKmrkfLDEQAID 2030
Cdd:COG4913    345 REIERLERELEER----ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAE----AEAALRD 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2031 REHERDVFQQEIQKLEQQLKVVPRFQpiseHQTRevEQLTNHLKEKTDKC---SELLlskeqlqrDIQERNEE----IEK 2103
Cdd:COG4913    417 LRRELRELEAEIASLERRKSNIPARL----LALR--DALAEALGLDEAELpfvGELI--------EVRPEEERwrgaIER 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2104 LefrVRELEQALLVSADTFQK----VEDRKQFGAV---EAKPELSLEVQLQAERDAIDRK----EKEITN-LEEQLEQFR 2171
Cdd:COG4913    483 V---LGGFALTLLVPPEHYAAalrwVNRLHLRGRLvyeRVRTGLPDPERPRLDPDSLAGKldfkPHPFRAwLEAELGRRF 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2172 --------EELEN------------KNEEVQQLHMQLEIQKK-----ESTTRLQELEQENKLFKDDMEKLGLAIKESDAV 2226
Cdd:COG4913    560 dyvcvdspEELRRhpraitragqvkGNGTRHEKDDRRRIRSRyvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAE 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2227 --STQDQHVLFGKFAQiIQEKEVEIDQLNEQIMKLQQQL-KITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNR--- 2300
Cdd:COG4913    640 ldALQERREALQRLAE-YSWDEIDVASAEREIAELEAELeRLDASSDDLAALEEQLEELEAELEELEEELDELKGEIgrl 718

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520 2301 EEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEM 2364
Cdd:COG4913    719 EKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARL 782
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
157-563 9.06e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 9.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  157 LEMMESELAGKQHEIEELNRELEEMrvtygtEGLQQLQEFEAAIKQRDGIITQLTANLQQARREkdetMREFLELTEQSQ 236
Cdd:COG4717     97 LEELEEELEELEAELEELREELEKL------EKLLQLLPLYQELEALEAELAELPERLEELEER----LEELRELEEELE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  237 KLQIQFQQLQAS-ETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQdkk 315
Cdd:COG4717    167 ELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE--- 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  316 vENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIK 395
Cdd:COG4717    244 -RLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELE 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  396 QLMG--------TVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR--QHVSQMEELKT 465
Cdd:COG4717    323 ELLAalglppdlSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAalEQAEEYQELKE 402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  466 RHKgEMENALRSYPNitvnEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEElsfsrEQIQ 545
Cdd:COG4717    403 ELE-ELEEQLEELLG----ELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED-----GELA 472

                          410
                   ....*....|....*...
gi 1622925520  546 RARQTIAEQESKLNEAQK 563
Cdd:COG4717    473 ELLQELEELKAELRELAE 490
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 700-899 1.11e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  700 SKLKDLQQSLvnsksEEMTLQINELQKEIEILRQEEKEkgtLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSI 779
Cdd:COG4942     27 AELEQLQQEI-----AELEKELAALKKEEKALLKQLAA---LERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  780 LKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1622925520  860 NYQELQEEYACLLKVKDD---LEDSKNKQELEYKSKLKALNEE 899
Cdd:COG4942    179 LLAELEEERAALEALKAErqkLLARLEKELAELAAELAELQQE 221
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 153-1006 1.16e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.59  E-value: 1.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  153 SLTHLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAaIKQRDGiitqltanlQQARREKDETMREFLELT 232
Cdd:TIGR00606  263 KIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYH-NHQRTV---------REKERELVDCQRELEKLN 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  233 EQSQKLQiqfqqLQASETLRNSTHSSTAADLLQAKQQIRTHQQQlEEQDHLLEDYQKKKEDFTMQISFLQEkIKVYEMEQ 312
Cdd:TIGR00606  333 KERRLLN-----QEKTELLVEQGRLQLQADRHQEHIRARDSLIQ-SLATRLELDGFERGPFSERQIKNFHT-LVIERQED 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  313 DKKVENSNKEEIQEKETIIEELNTKIieeekktlelKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSE 392
Cdd:TIGR00606  406 EAKTAAQLCADLQSKERLKQEQADEI----------RDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILE 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  393 EIKQLMGTVEELQKRNhKDSQFETDI-----VQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHVS----QMEEL 463
Cdd:TIGR00606  476 LDQELRKAERELSKAE-KNSLTETLKkevksLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMdkdeQIRKI 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  464 KTRHKGEMENALRSYPNITVNED-------QIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQL------ 530
Cdd:TIGR00606  555 KSRHSDELTSLLGYFPNKKQLEDwlhskskEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgs 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  531 EDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVED--------------LKAEIVSASESRKELELKHEAEVTNY 596
Cdd:TIGR00606  635 QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDenqsccpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKST 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  597 KIKLEMLEKEKNAVLDrMAESQEAELERLrtqllfshEEELSKLKEDLEiEHQINIEKLKDNLGIHYKQqidgLQNEMSQ 676
Cdd:TIGR00606  715 ESELKKKEKRRDEMLG-LAPGRQSIIDLK--------EKEIPELRNKLQ-KVNRDIQRLKNDIEEQETL----LGTIMPE 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  677 KIETMQFEKDNLITKQNQLILEISKlKDLQQSLVNSKSEEMTLQINELQKEIEilrQEEKEKGTLEQEVQELQLKIELLE 756
Cdd:TIGR00606  781 EESAKVCLTDVTIMERFQMELKDVE-RKIAQQAAKLQGSDLDRTVQQVNQEKQ---EKQHELDTVVSKIELNRKLIQDQQ 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  757 KQMKEkendLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSKSKDSVWEKEIEILTEENEDLKQQC 836
Cdd:TIGR00606  857 EQIQH----LKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK 932

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  837 IQLNEEIEKQRNTFSFAEKNFEVNYQELQEeyacllKVKDDLEDSKNKQELEYKSKLKALNE-ELHLQRINPTTVKTKSS 915
Cdd:TIGR00606  933 ETSNKKAQDKVNDIKEKVKNIHGYMKDIEN------KIQDGKDDYLKQKETELNTVNAQLEEcEKHQEKINEDMRLMRQD 1006

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  916 VfdedktfvaETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLADLSE-QLKQKHGEISFLNEEVKSLKQEKEQVLLRC 994
Cdd:TIGR00606 1007 I---------DTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQmQVLQMKQEHQKLEENIDLIKRNHVLALGRQ 1077

                          890
                   ....*....|..
gi 1622925520  995 RELEIIINHNRA 1006
Cdd:TIGR00606 1078 KGYEKEIKHFKK 1089
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1933-2718 1.20e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1933 RQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQA 2012
Cdd:pfam02463  205 QAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2013 LEKQLEKMRKFLDEqaidreherdvfQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTdkcSELLLSKEQLQR 2092
Cdd:pfam02463  285 EEELKLLAKEEEEL------------KSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI---EELEKELKELEI 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2093 DIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFRE 2172
Cdd:pfam02463  350 KREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEEL 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2173 ELENKNEEVQQLhmqleIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQL 2252
Cdd:pfam02463  430 EILEEEEESIEL-----KQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2253 NEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSL 2332
Cdd:pfam02463  505 ARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2333 PEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNilkeTNFKMNQLTQELFSLKRERESMEKIQSIPGKSVNMAIDD 2412
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR----AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2413 MSKDKPELEVVLTEDALKSLENQtyLKSFEENgkgsIINLETRLLQLESTVRAKDLELTQCYKQIKDMQEQGQSEIEVLQ 2492
Cdd:pfam02463  661 KSEVKASLSELTKELLEIQELQE--KAESELA----KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2493 KKILN-LQKILEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDEsgsnisaLTLRISELESQLV 2571
Cdd:pfam02463  735 NEELKlLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE-------KLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2572 EMHTSLILGKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQGGKERKRSPQDFEVLKTTTELFHSNEESGFLNELEALRA 2651
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520 2652 ESVATKAQLTGYKEKTEKLQ--GELLIKETNMASLQKDLSQVRDHLAEAKEKLSILEKEDKTAVQENKK 2718
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQklNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKE 956
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 231-845 1.35e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.51  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  231 LTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQE---KIKV 307
Cdd:TIGR00618  199 LTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEElraQEAV 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  308 YEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLT---------AADKLLGELQEQVVQKNQEIKNMKL 378
Cdd:TIGR00618  279 LEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAkllmkraahVKQQSSIEEQRRLLQTLHSQEIHIR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQ---------LRAELDEMYGQQIVQMK 449
Cdd:TIGR00618  359 DAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtrtsafrdLQGQLAHAKKQQELQQR 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  450 ----QELIRQHVSQMEELKTRHKGEMENALR-------SYPNITVNEDQIKLMNVAI---------------NELNIKLQ 503
Cdd:TIGR00618  439 yaelCAAAITCTAQCEKLEKIHLQESAQSLKereqqlqTKEQIHLQETRKKAVVLARllelqeepcplcgscIHPNPARQ 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  504 D------TNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVS 577
Cdd:TIGR00618  519 DidnpgpLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  578 ASESRKELELKHEAEVTNYKIKLEmlekEKNAVLDRMAESQEAElERLRTQLLFSHEEELSKLKEDLEiEHQINIEKLKD 657
Cdd:TIGR00618  599 LTEKLSEAEDMLACEQHALLRKLQ----PEQDLQDVRLHLQQCS-QELALKLTALHALQLTLTQERVR-EHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  658 NLGIHYKQQIDGLQNEMSQ--KIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ---INELQKEIEILR 732
Cdd:TIGR00618  673 ELLASRQLALQKMQSEKEQltYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARedaLNQSLKELMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  733 QEEKEKGTLEQEVQELQLKIEL--------LEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLI 804
Cdd:TIGR00618  753 RTVLKARTEAHFNNNEEVTAALqtgaelshLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQ 832

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 1622925520  805 FIDSIKSKSKDSVwekEIEILTEENEDLKQQCIQLNEEIEK 845
Cdd:TIGR00618  833 FLSRLEEKSATLG---EITHQLLKYEECSKQLAQLTQEQAK 870
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 319-547 1.45e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 1.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  319 SNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLM 398
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  399 GTVEELqkrnhkdsqfeTDIVQRMEQETQRKL-----EQLRAELDEMYGQQIVQMKQELIRQHVSQMEELKTRHKGEMEN 473
Cdd:COG4942    104 EELAEL-----------LRALYRLGRQPPLALllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  474 ALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRA 547
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1839-2385 1.48e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.51  E-value: 1.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1839 RQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELlCASNRLQELE 1918
Cdd:TIGR00618  307 QQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQH-TLTQHIHTLQ 385

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1919 AEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQET-EKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQ 1997
Cdd:TIGR00618  386 QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRdLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESA 465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1998 EKNAELMDLRQQNQALEKQLEKMRK----FLDEQAidrEHERDVFQQEIQ----------------KLEQQLKVVPRFQP 2057
Cdd:TIGR00618  466 QSLKEREQQLQTKEQIHLQETRKKAvvlaRLLELQ---EEPCPLCGSCIHpnparqdidnpgpltrRMQRGEQTYAQLET 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2058 ISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEAK 2137
Cdd:TIGR00618  543 SEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2138 PELSLEVQLQAERDAIDRKEKEITNLE-EQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2216
Cdd:TIGR00618  623 PEQDLQDVRLHLQQCSQELALKLTALHaLQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQC 702

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2217 GLAIKESDAV---STQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDL-----ETQIEC 2288
Cdd:TIGR00618  703 QTLLRELETHieeYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTaalqtGAELSH 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2289 LMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLdmviAEKLALEQQVETTNEEMTFTK 2368
Cdd:TIGR00618  783 LAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL----EEKSATLGEITHQLLKYEECS 858

                          570
                   ....*....|....*..
gi 1622925520 2369 NILKETNFKMNQLTQEL 2385
Cdd:TIGR00618  859 KQLAQLTQEQAKIIQLS 875
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1966-2263 1.49e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.49  E-value: 1.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1966 QAEKVrDDLQKQVKALEIDVEEQVsrfiELEQEKNAELMDLRQQNQALEKQLEKMRKFLD--EQAIDREHERDV-FQQEI 2042
Cdd:COG3096    345 QQEKI-ERYQEDLEELTERLEEQE----EVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyQQALDVQQTRAIqYQQAV 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2043 QKLE--QQLKVVP------------RFQPISEHQTREVEQLTNHL------KEKTDKCSELLLS--------------KE 2088
Cdd:COG3096    420 QALEkaRALCGLPdltpenaedylaAFRAKEQQATEEVLELEQKLsvadaaRRQFEKAYELVCKiageversqawqtaRE 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2089 QLQ--RDIQERNEEIEKLEFRVRELEQALlvsadtfqkvedRKQFGAVEAKPELSleVQLQAERDAIDrkekEITNLEEQ 2166
Cdd:COG3096    500 LLRryRSQQALAQRLQQLRAQLAELEQRL------------RQQQNAERLLEEFC--QRIGQQLDAAE----ELEELLAE 561

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2167 LEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL-------GLAIKESDAVSTQDQHVLfgkfa 2239
Cdd:COG3096    562 LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALerlreqsGEALADSQEVTAAMQQLL----- 636

                          330       340
                   ....*....|....*....|....
gi 1622925520 2240 qiiqEKEVEIDQLNEQIMKLQQQL 2263
Cdd:COG3096    637 ----EREREATVERDELAARKQAL 656
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2153-2505 1.73e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2153 IDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQL---EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQ 2229
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLnkdEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSK 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2230 DQHVLFGKFAQIIQeKEVEIDQLNEQIMKLQQQLK-----ITTDNKVIEEKNELIRDLETQIECLmsdqECVKRNREEEI 2304
Cdd:TIGR04523  108 INSEIKNDKEQKNK-LEVELNKLEKQKKENKKNIDkflteIKKKEKELEKLNNKYNDLKKQKEEL----ENELNLLEKEK 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2305 EQLNEVIEKLQQELaNIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQE 2384
Cdd:TIGR04523  183 LNIQKNIDKIKNKL-LKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2385 LFSLKREREsmEKIQSIpgKSVNMAIDDMSKDKPELEVVLTEdaLKSLENQTY---LKSFEENGKGSIINLETRLLQLES 2461
Cdd:TIGR04523  262 QNKIKKQLS--EKQKEL--EQNNKKIKELEKQLNQLKSEISD--LNNQKEQDWnkeLKSELKNQEKKLEEIQNQISQNNK 335

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1622925520 2462 TVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEK 2505
Cdd:TIGR04523  336 IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKEN 379
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1945-2396 2.44e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 50.51  E-value: 2.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1945 VEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALeIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFL 2024
Cdd:pfam05557   14 LQNEKKQMELEHKRARIELEKKASALKRQLDRESDRN-QELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2025 DEQAIDREHERDV----------FQQEIQKLEQQLKvvprfqpiseHQTREVEQLTNHLKEKTDKCSELllskEQLQRDI 2094
Cdd:pfam05557   93 NEKESQLADAREVisclknelseLRRQIQRAELELQ----------STNSELEELQERLDLLKAKASEA----EQLRQNL 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2095 QERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfgAVEAKPELSLEVQLQAERDAIDRKEKEITN-LEEQLEQFREE 2173
Cdd:pfam05557  159 EKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKS--ELARIPELEKELERLREHNKHLNENIENKLlLKEEVEDLKRK 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2174 LEnKNEEVQQLHMQLEIQKKESTTRLQELEqenKLFKDDmeklGLAIKESDAVSTQDQHVLFG-------KFAQIIQEKE 2246
Cdd:pfam05557  237 LE-REEKYREEAATLELEKEKLEQELQSWV---KLAQDT----GLNLRSPEDLSRRIEQLQQReivlkeeNSSLTSSARQ 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2247 VEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLN------------EVIEKL 2314
Cdd:pfam05557  309 LEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTmsnyspqlleriEEAEDM 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2315 QQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETtnEEMTFTKNILKETNFKMNQLTQELFSLKRERES 2394
Cdd:pfam05557  389 TQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESL--ADPSYSKEEVDSLRRKLETLELERQRLREQKNE 466


                   ..
gi 1622925520 2395 ME 2396
Cdd:pfam05557  467 LE 468
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 134-429 2.92e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.12  E-value: 2.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  134 LREEEFGVDDSYSEQGAQYSLTHLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEaaikqrdgiitqltaN 213
Cdd:pfam17380  318 LEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELE---------------R 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  214 LQQARREKDETMREFLElteQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQqiRTHQQQLEEQDHLLEDYQKKKED 293
Cdd:pfam17380  383 LQMERQQKNERVRQELE---AARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ--REVRRLEEERAREMERVRLEEQE 457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  294 FTMQISFLQEKikvyemEQDKKVENSNKEEIQEKETIIEELNTKIIEEE-----KKTLELKDKLTAADKLLGELQEQVVQ 368
Cdd:pfam17380  458 RQQQVERLRQQ------EEERKRKKLELEKEKRDRKRAEEQRRKILEKEleerkQAMIEEERKRKLLEKEMEERQKAIYE 531

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520  369 KNQEiknMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRK 429
Cdd:pfam17380  532 EERR---REAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARA 589
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
214-629 3.08e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 3.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  214 LQQARREKDETMREFLELTEQSQKLQIQFQQLQASET-----LRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQ 288
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEelreeLEKLEKLLQLLPLYQELEALEAELAELPERLEELEERL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  289 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNtkiieeekktlELKDKLTAADKLLGELQEQVVQ 368
Cdd:COG4717    156 EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE-----------ELQQRLAELEEELEEAQEELEE 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  369 KNQEIKNMKLELTNSKQKERQSSEEIKQL-MGTVEELQKRNHKDSQFETDI----------VQRMEQETQRKLEQLRAEL 437
Cdd:COG4717    225 LEEELEQLENELEAAALEERLKEARLLLLiAAALLALLGLGGSLLSLILTIagvlflvlglLALLFLLLAREKASLGKEA 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  438 DEMYGQQIVQMKQELirqhvsQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELN--IKLQDTNSQKEKLKEE 515
Cdd:COG4717    305 EELQALPALEELEEE------ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeeLQLEELEQEIAALLAE 378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  516 LGV----ILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEaqkslstvEDLKAEIVSASESRKELELKHE- 590
Cdd:COG4717    379 AGVedeeELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--------EELEEELEELEEELEELEEELEe 450

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1622925520  591 --AEVTNYKIKLEMLEKeknavlDRMAESQEAELERLRTQL 629
Cdd:COG4717    451 lrEELAELEAELEQLEE------DGELAELLQELEELKAEL 485
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3021-3320 3.33e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 3.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3021 QRIQEQGVEYQAAMEYLQKADRRSLLSEIQALHAQMNGRKITLKREQENEKSSQElleyNIQQKQSQMLEMQVELSSMKD 3100
Cdd:TIGR02168  206 ERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTA----ELQELEEKLEELRLEVSELEE 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3101 RATELQ------------------------EQLSSEKMVVAELRSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTD 3156
Cdd:TIGR02168  282 EIEELQkelyalaneisrleqqkqilrerlANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3157 EVHLLNDTLASEQKKSRELQWALEKEKAKLGHSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQ-QKIESQ 3235
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3236 RMLYDAQLSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSNdgtgqsrpslpsEDLLKELQKQLEEKHSRIV 3315
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR------------LDSLERLQENLEGFSEGVK 509


                   ....*
gi 1622925520 3316 ELLNE 3320
Cdd:TIGR02168  510 ALLKN 514
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 535-764 3.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 3.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  535 EELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRM 614
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  615 AESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQnemsQKIETMQFEKDNLITKQNQ 694
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR----ADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  695 LILEISKLKDLQQSLVNSKSEEMTLqINELQKEIEILRQEEKEkgtLEQEVQELQLKIELLEKQMKEKEN 764
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKL-LARLEKELAELAAELAE---LQQEAEELEALIARLEAEAAAAAE 241
PTZ00121 PTZ00121
MAEBL; Provisional
 454-1198 3.82e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 3.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  454 RQHVSQMEELKTRHKGEMENALRSYPNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLK--EELGVILEEKCALQ-RQL 530
Cdd:PTZ00121  1063 KAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKkaEDARKAEEARKAEDaRKA 1142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  531 EDLFEELSFSREQIQRArqtiAEQESKLNEAQKSlstvEDLKaeivSASESRKELELKHEAEVTNYKIKLEMLEKEKNAV 610
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARK----AEDARKAEEARKA----EDAK----KAEAARKAEEVRKAEELRKAEDARKAEAARKAEE 1210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  611 LDRMAESQEAELERlRTQLLFSHEEELSKLKEDLEIEHQIN---IEKLKDNLGIHYKQQIDGLQNEMSQKIEtmqfekdn 687
Cdd:PTZ00121  1211 ERKAEEARKAEDAK-KAEAVKKAEEAKKDAEEAKKAEEERNneeIRKFEEARMAHFARRQAAIKAEEARKAD-------- 1281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  688 litkqnqlilEISKLKDLQQSLVNSKSEEMTlQINELQKEIEilrqEEKEKGTLEQEVQELQLKIELLEKQMKE-KENDL 766
Cdd:PTZ00121  1282 ----------ELKKAEEKKKADEAKKAEEKK-KADEAKKKAE----EAKKADEAKKKAEEAKKKADAAKKKAEEaKKAAE 1346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  767 QEKFTQLEAENSILKDEKKALEDMLKihtpdnQEERLIFIDSIKSKSKDsvwEKEIEILTEENEDLKQQCIQLNEEIEKQ 846
Cdd:PTZ00121  1347 AAKAEAEAAADEAEAAEEKAEAAEKK------KEEAKKKADAAKKKAEE---KKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  847 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDL----EDSKNKQELEYKSKLKALNEELhlqrinpttvKTKSsvfdEDKT 922
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKADEAKKKAEEAKKADEAkkkaEEAKKAEEAKKKAEEAKKADEA----------KKKA----EEAK 1483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  923 FVAETLEMGEVVEKDTTELMEKLEVTKR----EKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQ-EKEQVLLRCREL 997
Cdd:PTZ00121  1484 KADEAKKKAEEAKKKADEAKKAAEAKKKadeaKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADElKKAEELKKAEEK 1563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  998 EIIINHNRAGNVQSCDTQVSSLSDGVVTMTSRDAEGSVSKVNKSFGEESKIMVEDKVSFENMTTGKESKQEQLILDHLPS 1077
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1078 VTKESSLRAAQPSENDKLQKELNVLKSEQN-----DLRLQMEAQRICLSLVY-----STHVDQVREYMENEKDKALCSLK 1147
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkaeEAKKAEEDEKKAAEALKkeaeeAKKAEELKKKEAEEKKKAEELKK 1723

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1148 ---------EELISAQEEKIKELQKIHQLELQNTKTQETGDEGKPLHLLIGKLRKAVSEE 1198
Cdd:PTZ00121  1724 aeeenkikaEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 3092-3399 4.00e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 4.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3092 QVELSSMKDRATELQEQLSSEKMVVAELRSELAqtklELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKK 3171
Cdd:TIGR02168  224 ELELALLVLRLEELREELEELQEELKEAEEELE----ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3172 srelqwaLEKEKAKLGHSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYD---AQLSEEHG 3248
Cdd:TIGR02168  300 -------LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3249 RNLELQVLLESEKVRIREMSSTLDRERelhAQLQSNdgtgqsrpslpsEDLLKELQKQLEEKHSRIVELLNETEKYKLDS 3328
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIASLN---NEIERL------------EARLERLEDRRERLQQEIEELLKKLEEAELKE 437

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 3329 LQTRQqmekdrqvhrktlqteqeanTEGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQ 3399
Cdd:TIGR02168  438 LQAEL--------------------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
161-681 4.38e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 4.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKqrdgiitqltanlqQARREKDETMREFLELTEQSQKLQI 240
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIE--------------RLERELEERERRRARLEALLAALGL 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  241 QFqqlqasetlrnsthSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQ----KKKEDFTMQISFLQEKIKVYEmeqdKKV 316
Cdd:COG4913    374 PL--------------PASAEEFAALRAEAAALLEALEEELEALEEALaeaeAALRDLRRELRELEAEIASLE----RRK 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  317 ENSNKEEIQEKETIIEELNtkIIEEEKK----TLELKDK----LTAADKLLGEL-------QEQVVQKNQEIKNMKLelt 381
Cdd:COG4913    436 SNIPARLLALRDALAEALG--LDEAELPfvgeLIEVRPEeerwRGAIERVLGGFaltllvpPEHYAAALRWVNRLHL--- 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  382 nskqKERQSSEEIKQlmGTVEELQKRNHKDSqfetdIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHVS--- 458
Cdd:COG4913    511 ----RGRLVYERVRT--GLPDPERPRLDPDS-----LAGKLDFKPHPFRAWLEAELGRRFDYVCVDSPEELRRHPRAitr 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  459 --QMEELKTRHKGEMENALRSYPNI-TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRqledlFE 535
Cdd:COG4913    580 agQVKGNGTRHEKDDRRRIRSRYVLgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR-----LA 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  536 ELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAevtnykiklemLEKEKNAVLDRMA 615
Cdd:COG4913    655 EYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDE-----------LKGEIGRLEKELE 723

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520  616 ESQEaELERLRTQLLFSHEEELSKLKEDLEIE-HQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETM 681
Cdd:COG4913    724 QAEE-ELDELQDRLEAAEDLARLELRALLEERfAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1852-2184 5.41e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 5.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1852 EDLRERLHEESRAREQ------LAVELSKAEGVIdgYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQ 1925
Cdd:TIGR02169  194 DEKRQQLERLRREREKaeryqaLLKEKREYEGYE--LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1926 EERELLSRQKEAMKAEagpveqqllqETEKLMKEKLEVQCQAEKVRDDLQKQVKALEiDVEEQVSRFIELEQEKNAELMD 2005
Cdd:TIGR02169  272 QLLEELNKKIKDLGEE----------EQLRVKEKIGELEAEIASLERSIAEKERELE-DAEERLAKLEAEIDKLLAEIEE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2006 LRQQNQALEKQLEKmrkfLDEQAIDREHERDVFQQEIQKLEQQLKVVprFQPISEHQtREVEQLTNHLKEKTDKCSELLL 2085
Cdd:TIGR02169  341 LEREIEEERKRRDK----LTEEYAELKEELEDLRAELEEVDKEFAET--RDELKDYR-EKLEKLKREINELKRELDRLQE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2086 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfgaveakpelSLEVQLQAERDAIDRKEKEITNLEE 2165
Cdd:TIGR02169  414 ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE----------QLAADLSKYEQELYDLKEEYDRVEK 483

                          330
                   ....*....|....*....
gi 1622925520 2166 QLEQFREELENKNEEVQQL 2184
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARAS 502
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1852-2398 6.37e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 6.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1852 EDLRERLHEESRAREQLAVELSKAEGV---IDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQeleaEQQQIQEER 1928
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKRTENIeelIKEKEKELEEVLREINEISSELPELREELEKLEKEVK----ELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1929 ELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALE-IDVEEQVSRFIELEQEKNAELMDLR 2007
Cdd:PRK03918   241 EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2008 QQNQALEKQLEKMRKfLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKCSELL-LS 2086
Cdd:PRK03918   321 EEINGIEERIKELEE-KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELeKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2087 KEQLQRDIQERNEEIEKLEFRVRELEQAL--LVSADTFQKVEDRKqfgaVEAKPELSLEVQLQAERDAIDRKEKEITNLE 2164
Cdd:PRK03918   400 KEEIEEEISKITARIGELKKEIKELKKAIeeLKKAKGKCPVCGRE----LTEEHRKELLEEYTAELKRIEKELKEIEEKE 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2165 EQLEQFREELE---NKNEEVQQLHMQLE----IQKKESTTRLQELEQENKLFKDDMEKLG-----LAIKESDAVSTQDQH 2232
Cdd:PRK03918   476 RKLRKELRELEkvlKKESELIKLKELAEqlkeLEEKLKKYNLEELEKKAEEYEKLKEKLIklkgeIKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2233 VLFGKFAQIIQEKEVEIDQLNEQIMKL------QQQLKITTDNKVIEEKNELiRDLETQIECLMSDQECVKRNREEEIEQ 2306
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELgfesveELEERLKELEPFYNEYLEL-KDAEKELEREEKELKKLEEELDKAFEE 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2307 LNEV---IEKLQQELANIGQKTLVDAH-SLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKEtnfkMNQLT 2382
Cdd:PRK03918   635 LAETekrLEELRKELEELEKKYSEEEYeELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE----REKAK 710

                          570
                   ....*....|....*.
gi 1622925520 2383 QELFSLKRERESMEKI 2398
Cdd:PRK03918   711 KELEKLEKALERVEEL 726
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1807-2397 6.44e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 6.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1807 AAVEKLLEAISETSSQLEHAKVTQTELMRE---SFRQKQEATE-SLKCQEDLRERLHEESRAREQLAVELSKA--EGVID 1880
Cdd:pfam12128  318 AKDRSELEALEDQHGAFLDADIETAAADQEqlpSWQSELENLEeRLKALTGKHQDVTAKYNRRRSKIKEQNNRdiAGIKD 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1881 GYADEKTLFERQIQEKTDIIDRLEQEL---LCASNRLQELEAEQQQIQEERELLsRQKEAMKAEAGPVEQQLLQETEKLM 1957
Cdd:pfam12128  398 KLAKIREARDRQLAVAEDDLQALESELreqLEAGKLEFNEEEYRLKSRLGELKL-RLNQATATPELLLQLENFDERIERA 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1958 KEKLEvqcQAEKVRDDLQKQVKALEIDVEEQVSRFieleQEKNAELMDLRQQNQALEKQLE----KMRKFLDEQAID-RE 2032
Cdd:pfam12128  477 REEQE---AANAEVERLQSELRQARKRRDQASEAL----RQASRRLEERQSALDELELQLFpqagTLLHFLRKEAPDwEQ 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2033 HERDVFQQEiqkLEQQLKVVPRFQPISEHQTREVEQLTNHLKektdkcselllskeqlQRDIQERNEEIEKLEFRVRELE 2112
Cdd:pfam12128  550 SIGKVISPE---LLHRTDLDPEVWDGSVGGELNLYGVKLDLK----------------RIDVPEWAASEEELRERLDKAE 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2113 QALlvsadtfQKVEDRKQfgaveakpelSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQ- 2191
Cdd:pfam12128  611 EAL-------QSAREKQA----------AAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAl 673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2192 ---KKESTTRLQELEQENKLFKDDMEKLGLAIKE-SDAVSTQDQHvlfgKFAQIIQEKEVEIDQLNEQIMKLQQQLKITT 2267
Cdd:pfam12128  674 aerKDSANERLNSLEAQLKQLDKKHQAWLEEQKEqKREARTEKQA----YWQVVEGALDAQLALLKAAIAARRSGAKAEL 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2268 DNKVIEEKNEL----------------IRDLETQIECLMSDQECVKR--------------NREEEIEQLNEVIEKLQQE 2317
Cdd:pfam12128  750 KALETWYKRDLaslgvdpdviaklkreIRTLERKIERIAVRRQEVLRyfdwyqetwlqrrpRLATQLSNIERAISELQQQ 829

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2318 LANIGQKTLVDAHSLPEEADSLKHQLDMVIAE--KLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKRERESM 2395
Cdd:pfam12128  830 LARLIADTKLRRAKLEMERKASEKQQVRLSENlrGLRCEMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESV 909


                   ..
gi 1622925520 2396 EK 2397
Cdd:pfam12128  910 KK 911
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
525-986 7.10e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 7.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  525 ALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEA---EVTNYKIKLE 601
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREElaeEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  602 MLEKEKNAVLDrmaesqEAELERLRTQLLFSHEEELSKLKEDLEIEhqinIEKLKDNLGIHyKQQIDGLQnemsQKIETM 681
Cdd:PRK02224   290 ELEEERDDLLA------EAGLDDADAEAVEARREELEDRDEELRDR----LEECRVAAQAH-NEEAESLR----EDADDL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  682 QFEKDNLITKQNQLILEISKLKdlqqslvnSKSEEMTLQINELQKEIEILRqeeKEKGTLEQEVQELQLKIELLEkqmkE 761
Cdd:PRK02224   355 EERAEELREEAAELESELEEAR--------EAVEDRREEIEELEEEIEELR---ERFGDAPVDLGNAEDFLEELR----E 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  762 KENDLQEKFTQLEAENSILKD---EKKALEDMLKIHTPDNQEERLIFIDSIKSKskdsvwEKEIEILTEENEDLKQQCIQ 838
Cdd:PRK02224   420 ERDELREREAELEATLRTARErveEAEALLEAGKCPECGQPVEGSPHVETIEED------RERVEELEAELEDLEEEVEE 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  839 LNEEIEKQRnTFSFAEKNFEV------NYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKT 912
Cdd:PRK02224   494 VEERLERAE-DLVEAEDRIERleerreDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE 572

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  913 KSSVFDEDKTFVAETLEMGEVVEkdttELMEKLEVTKREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQE 986
Cdd:PRK02224   573 EVAELNSKLAELKERIESLERIR----TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAE 642
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 503-782 7.60e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.02  E-value: 7.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  503 QDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESR 582
Cdd:pfam01576  204 QELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  583 KELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEaelerLRTQllfsHEEELSKLKEDLEIEHQInieklkdnlgih 662
Cdd:pfam01576  284 RAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQE-----LRSK----REQEVTELKKALEEETRS------------ 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  663 YKQQIDGLQNEMSQKIETMQFEKDNliTKQNQLILEISKlkdlqQSLVNskseemtlQINELQKEIEILRQ----EEKEK 738
Cdd:pfam01576  343 HEAQLQEMRQKHTQALEELTEQLEQ--AKRNKANLEKAK-----QALES--------ENAELQAELRTLQQakqdSEHKR 407

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1622925520  739 GTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKD 782
Cdd:pfam01576  408 KKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNE 451
COG5022 COG5022
Myosin heavy chain [General function prediction only];
356-788 8.59e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.92  E-value: 8.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  356 DKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKR--NHKDSQFETDIVQRMEQeTQRKLEQL 433
Cdd:COG5022    809 RKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRfsLLKKETIYLQSAQRVEL-AERQLQEL 887

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  434 RAELDEM-----YGQQIVQMKQELIRQHVSQME---ELKTRHKGEMENALRsypNITVNEDQIKlmNVAINELNIKLQDT 505
Cdd:COG5022    888 KIDVKSIsslklVNLELESEIIELKKSLSSDLIenlEFKTELIARLKKLLN---NIDLEEGPSI--EYVKLPELNKLHEV 962

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  506 NSQKEKLKEELGVILEekcalqrQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVS-------- 577
Cdd:COG5022    963 ESKLKETSEEYEDLLK-------KSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAElqsaskii 1035

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  578 ASESRKELELKHEAEVTNykikleMLEKEKNAVLDRMaesqEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKD 657
Cdd:COG5022   1036 SSESTELSILKPLQKLKG------LLLLENNQLQARY----KALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTN 1105

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  658 NlgihykqqiDGLQNEMSQKIETMQFEKDNLITKQNQLILeiSKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKE 737
Cdd:COG5022   1106 R---------NLVKPANVLQFIVAQMIKLNLLQEISKFLS--QLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPF 1174

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  738 KGTLEQE---VQELQLKIELLEKQMKEKENDLQEKFtQLEAENSILKDEKKALE 788
Cdd:COG5022   1175 AALSEKRlyqSALYDEKSKLSSSEVNDLKNELIALF-SKIFSGWPRGDKLKKLI 1227
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 684-1006 9.43e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  684 EKDNLITK-QNQLILEIsklKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ-LKIELLEKQMKE 761
Cdd:PRK05771    17 YKDEVLEAlHELGVVHI---EDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvKSLEELIKDVEE 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  762 KENDLQEKFTQLEAENSILKDEKKALEDMLKihtpdnqeerlifidsikskskdsvwekEIEILTEenedlkqqciqLNE 841
Cdd:PRK05771    94 ELEKIEKEIKELEEEISELENEIKELEQEIE----------------------------RLEPWGN-----------FDL 134

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  842 EIEKQRNTfsfaeKNFEVNYQELQEEYACLLKvkddLEDSKNKQELEYKSKLKALneelhlqrINPTTVKtkssvfdEDK 921
Cdd:PRK05771   135 DLSLLLGF-----KYVSVFVGTVPEDKLEELK----LESDVENVEYISTDKGYVY--------VVVVVLK-------ELS 190

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  922 TFVAETLEMGEVVEKDTtelmeklevtkREKLELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRE-LEII 1000
Cdd:PRK05771   191 DEVEEELKKLGFERLEL-----------EEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEyLEIE 259


                   ....*.
gi 1622925520 1001 INHNRA 1006
Cdd:PRK05771   260 LERAEA 265
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1986-2223 9.75e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 9.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1986 EEQVSRFIELEQEKNAE-LMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQL-----KVVPRfqpIS 2059
Cdd:PRK05771    27 ELGVVHIEDLKEELSNErLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVeeeleKIEKE---IK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2060 EhQTREVEQLTNHLKEKTDKCSEL------------LLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADT------ 2121
Cdd:PRK05771   104 E-LEEEISELENEIKELEQEIERLepwgnfdldlslLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKgyvyvv 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2122 -FQKVEDRKQFGAVEAKPELSlEVQLQAER---DAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ----LEIQKK 2193
Cdd:PRK05771   183 vVVLKELSDEVEEELKKLGFE-RLELEEEGtpsELIREIKEELEEIEKERESLLEELKELAKKYLEELLAlyeyLEIELE 261

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1622925520 2194 ESTTRLQELEqENKLF-------KDDMEKLGLAIKES 2223
Cdd:PRK05771   262 RAEALSKFLK-TDKTFaiegwvpEDRVKKLKELIDKA 297
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
444-683 9.91e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 9.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  444 QIVQMKQ-----ELIRQHV---SQMEELKTRHKGEMENALRSYPNITVNEDQIKLMN--VAINELNIKLQDTNSQKEKLK 513
Cdd:COG4913    199 KTQSFKPigdldDFVREYMleePDTFEAADALVEHFDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLR 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  514 EELGVILEEKCA--LQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLST-----VEDLKAEIVSASESRKELE 586
Cdd:COG4913    279 AALRLWFAQRRLelLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGnggdrLEQLEREIERLERELEERE 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  587 LKHEaevtNYKIKLEMLE----------KEKNAVLDRMAESQEAELERLRTQlLFSHEEELSKLKEDL-EIEHQIN-IEK 654
Cdd:COG4913    359 RRRA----RLEALLAALGlplpasaeefAALRAEAAALLEALEEELEALEEA-LAEAEAALRDLRRELrELEAEIAsLER 433

                          250       260
                   ....*....|....*....|....*....
gi 1622925520  655 LKDNLGIHYKQQIDGLQNEMSQKIETMQF 683
Cdd:COG4913    434 RKSNIPARLLALRDALAEALGLDEAELPF 462
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
489-776 1.00e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 1.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  489 KLMNVAINELNikLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSF---SREQIQRARQTIAEQ------ESKLN 559
Cdd:COG3206     94 PVLERVVDKLN--LDEDPLGEEASREAAIERLRKNLTVEPVKGSNVIEISYtspDPELAAAVANALAEAyleqnlELRRE 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  560 EAQKSLSTVEDLKAEIvsasesRKELELKhEAEVTNYKIK--LEMLEKEKNAVLDRMAESqEAELERLRTQLLfSHEEEL 637
Cdd:COG3206    172 EARKALEFLEEQLPEL------RKELEEA-EAALEEFRQKngLVDLSEEAKLLLQQLSEL-ESQLAEARAELA-EAEARL 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  638 SKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL-ILEISKLKDLQQSLVNSKSEE 716
Cdd:COG3206    243 AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIaALRAQLQQEAQRILASLEAEL 322

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  717 MTL--QINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMkekeNDLQEKFTQLEAE 776
Cdd:COG3206    323 EALqaREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELY----ESLLQRLEEARLA 380
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
239-598 1.03e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  239 QIQFQQLQASETLRNSTHSSTAADLLQAKQQI---RTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDK- 314
Cdd:COG3206     58 TLLVEPQSSDVLLSGLSSLSASDSPLETQIEIlksRPVLERVVDKLNLDEDPLGEEASREAAIERLRKNLTVEPVKGSNv 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  315 ---KVENSNKEEIQEketIIEELNTKIIEE--EKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKleltnSKQKERQ 389
Cdd:COG3206    138 ieiSYTSPDPELAAA---VANALAEAYLEQnlELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVD 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  390 SSEEIKQLMGTVEELQkrnhkdSQFETdiVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHVSQMEELKTRHKG 469
Cdd:COG3206    210 LSEEAKLLLQQLSELE------SQLAE--ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAE 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  470 EMENALRSYPnitvnedqiklmnvainelniKLQDTNSQKEKLKEELgvileeKCALQRQLEDLFEELSFSREQIQRARQ 549
Cdd:COG3206    282 LSARYTPNHP---------------------DVIALRAQIAALRAQL------QQEAQRILASLEAELEALQAREASLQA 334

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622925520  550 TIAEQESKLNEAQKSLSTVEDLKAEIVSASE-------SRKELELKHEAEVTNYKI 598
Cdd:COG3206    335 QLAQLEARLAELPELEAELRRLEREVEVARElyesllqRLEEARLAEALTVGNVRV 390
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 233-628 1.15e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 48.20  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  233 EQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME- 311
Cdd:pfam05557   48 DRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELEl 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  312 --QDKKVENSNkEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVvQKNQEIKNMKLELTNSKQKER- 388
Cdd:pfam05557  128 qsTNSELEELQ-ERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQE-QDSEIVKNSKSELARIPELEKe 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  389 --QSSEEIKQLMGTVE--ELQKRNHKDSQFETDIVQRMEQET---QRKLEQLRAEL------DEMYGQQIVqmKQELIRQ 455
Cdd:pfam05557  206 leRLREHNKHLNENIEnkLLLKEEVEDLKRKLEREEKYREEAatlELEKEKLEQELqswvklAQDTGLNLR--SPEDLSR 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  456 HVSQMEELKTRHKGE---MENALRSYP-NITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLE 531
Cdd:pfam05557  284 RIEQLQQREIVLKEEnssLTSSARQLEkARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILE 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  532 DLFEELSFSR-------------EQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEA-----EV 593
Cdd:pfam05557  364 SYDKELTMSNyspqllerieeaeDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPsyskeEV 443

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 1622925520  594 TNYKIKLEMLEKEkNAVLDRMAESQEAELERLRTQ 628
Cdd:pfam05557  444 DSLRRKLETLELE-RQRLREQKNELEMELERRCLQ 477
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 577-792 1.29e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  577 SASESRKELElKHEAEVTNYKIKLEMLEKEKNAVLDRMAEsQEAELERLrTQLLFSHEEELSKLKEDLEiEHQINIEKLK 656
Cdd:COG4942     21 AAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAA-LERRIAAL-ARRIRALEQELAALEAELA-ELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  657 dnlgihykQQIDGLQNEMSQKIETMQ----FEKDNLITKQNQLILEISKLKDLQQslVNSKSEEMTLQINELQKEIEILR 732
Cdd:COG4942     97 --------AELEAQKEELAELLRALYrlgrQPPLALLLSPEDFLDAVRRLQYLKY--LAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  733 QE-EKEKGTLEQEVQELQLKIELLEKQMKEKE---NDLQEKFTQLEAENSILKDEKKALEDMLK 792
Cdd:COG4942    167 AElEAERAELEALLAELEEERAALEALKAERQkllARLEKELAELAAELAELQQEAEELEALIA 230
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 307-986 1.41e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.12  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  307 VYEMEQDKKVENSNKEEIQEKETIIEELNTKiieeEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKnmklELTNSKQK 386
Cdd:TIGR00606  185 IKALETLRQVRQTQGQKVQEHQMELKYLKQY----KEKACEIRDQITSKEAQLESSREIVKSYENELD----PLKNRLKE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  387 ERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRaELDEMYGQQIVQMKQELIRQH-----VSQME 461
Cdd:TIGR00606  257 IEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLN-DLYHNHQRTVREKERELVDCQrelekLNKER 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  462 ELKTRHKGEMENalrsypnitvnEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGViLEEKCALQRQLEDLFEELSFSR 541
Cdd:TIGR00606  336 RLLNQEKTELLV-----------EQGRLQLQADRHQEHIRARDSLIQSLATRLELDG-FERGPFSERQIKNFHTLVIERQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  542 EQIQR-ARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEA 620
Cdd:TIGR00606  404 EDEAKtAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKA 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  621 ELERLRTQLLFSHE----EELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDglQNEMSQKIETMQFEK----------- 685
Cdd:TIGR00606  484 ERELSKAEKNSLTEtlkkEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT--QMEMLTKDKMDKDEQirkiksrhsde 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  686 ---------------DNLITKQNQLILEISKLKDLQQSLvnSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQL 750
Cdd:TIGR00606  562 ltsllgyfpnkkqleDWLHSKSKEINQTRDRLAKLNKEL--ASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEES 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  751 KIELLEKQMKEKENDL----------QEKFTQLEAENSI--------------LKDEKKALEDMLKIhTPDNQEERLIFI 806
Cdd:TIGR00606  640 DLERLKEEIEKSSKQRamlagatavySQFITQLTDENQSccpvcqrvfqteaeLQEFISDLQSKLRL-APDKLKSTESEL 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  807 DSIKSKS-----KDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKV------K 875
Cdd:TIGR00606  719 KKKEKRRdemlgLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtimerfQ 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  876 DDLEDSKNKQElEYKSKLKALNEELHLQRINpTTVKTKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLEL 955
Cdd:TIGR00606  799 MELKDVERKIA-QQAAKLQGSDLDRTVQQVN-QEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQI 876

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1622925520  956 S---QRLADLSEQLKQKHGEISFLNEEVKSLKQE 986
Cdd:TIGR00606  877 GtnlQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2144-2321 1.42e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2144 VQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAI--K 2221
Cdd:COG1579     10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2222 ESDAVSTQdqhvlfgkfaqiIQEKEVEIDQLNEQIMKLQQQlkittdnkvIEEKNELIRDLETQIECLMSDQECVKRNRE 2301
Cdd:COG1579     90 EYEALQKE------------IESLKRRISDLEDEILELMER---------IEELEEELAELEAELAELEAELEEKKAELD 148

                          170       180
                   ....*....|....*....|
gi 1622925520 2302 EEIEQLNEVIEKLQQELANI 2321
Cdd:COG1579    149 EELAELEAELEELEAEREEL 168
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 494-738 1.44e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  494 AINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKA 573
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  574 EIvsasesRKEL-ELKHEAEVTNYKIKLEMLEKEKNA--------VLDRMAESQEAELERLRTQLlfsheEELSKLKEDL 644
Cdd:COG4942    101 AQ------KEELaELLRALYRLGRQPPLALLLSPEDFldavrrlqYLKYLAPARREQAEELRADL-----AELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  645 EIEhqinieklkdnlgihyKQQIDGLQNEMSQKIETMQfekdNLITKQNQLILEISKLKDLQQslvnSKSEEMTLQINEL 724
Cdd:COG4942    170 EAE----------------RAELEALLAELEEERAALE----ALKAERQKLLARLEKELAELA----AELAELQQEAEEL 225

                          250
                   ....*....|....
gi 1622925520  725 QKEIEILRQEEKEK 738
Cdd:COG4942    226 EALIARLEAEAAAA 239
PRK01156 PRK01156
chromosome segregation protein; Provisional
 471-1002 1.51e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  471 MENALRSYpnitvnEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDL---FEELSFSREQIQRA 547
Cdd:PRK01156   188 LEEKLKSS------NLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELsslEDMKNRYESEIKTA 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  548 RQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRT 627
Cdd:PRK01156   262 ESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDY 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  628 QLLFSHEEELSKLKEDLEIEHQ------INIEKLKDNLGiHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEI-- 699
Cdd:PRK01156   342 IKKKSRYDDLNNQILELEGYEMdynsylKSIESLKKKIE-EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLqd 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  700 --SKLKDLQQSLVNSKSEEMtlqinELQKEIEILRQEEKEK---GTLEQEvqelqlKIELLEKQMKEKENDLQEKFTQLE 774
Cdd:PRK01156   421 isSKVSSLNQRIRALRENLD-----ELSRNMEMLNGQSVCPvcgTTLGEE------KSNHIINHYNEKKSRLEEKIREIE 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  775 AENSILKDEKKALEDMLKIHTPDNQEERLIFIDSIKSK----SKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNT- 849
Cdd:PRK01156   490 IEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESAradlEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTs 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  850 -FSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEY-------KSKLKALNEELHLQRINPTTVKTKSSVFDEdk 921
Cdd:PRK01156   570 wLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFpddksyiDKSIREIENEANNLNNKYNEIQENKILIEK-- 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  922 tfvaetleMGEVVEKDTTELMEKLEVTKREKlELSQRLADLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIII 1001
Cdd:PRK01156   648 --------LRGKIDNYKKQIAEIDSIIPDLK-EITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRI 718


                   .
gi 1622925520 1002 N 1002
Cdd:PRK01156   719 N 719
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
161-640 1.70e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  161 ESELAGKQHEIEELNRELEEMRvtygteglQQLQEFEAAIKQRDGI-ITQLTANLQQARREKDETMREFLELTEQSQKLQ 239
Cdd:COG4913    301 RAELARLEAELERLEARLDALR--------EELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALG 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  240 IQFqqlqasetlrnsthSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQ----KKKEDFTMQISFLQEKIKVYEmeqdKK 315
Cdd:COG4913    373 LPL--------------PASAEEFAALRAEAAALLEALEEELEALEEALaeaeAALRDLRRELRELEAEIASLE----RR 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  316 VENSNKEEIQEKETIIEELNtkIIEEEKK----TLELKDK----LTAADKLLGEL-------QEQVVQKNQEIKNMKLEL 380
Cdd:COG4913    435 KSNIPARLLALRDALAEALG--LDEAELPfvgeLIEVRPEeerwRGAIERVLGGFaltllvpPEHYAAALRWVNRLHLRG 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  381 --------TNSKQKERQSSEE-----------------IKQLMG---------TVEELQK----------RNHKDSQFET 416
Cdd:COG4913    513 rlvyervrTGLPDPERPRLDPdslagkldfkphpfrawLEAELGrrfdyvcvdSPEELRRhpraitragqVKGNGTRHEK 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  417 DIVQRMEQE------TQRKLEQLRAELDEMygqqivqmkQELIRQHVSQMEELKTRHKgEMENALRSYPNIT-VNEDQIK 489
Cdd:COG4913    593 DDRRRIRSRyvlgfdNRAKLAALEAELAEL---------EEELAEAEERLEALEAELD-ALQERREALQRLAeYSWDEID 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  490 LMnvainELNIKLQDTNSQKEKLKEELGVILEekcaLQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVE 569
Cdd:COG4913    663 VA-----SAEREIAELEAELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622925520  570 DLKAEIVSASESRKELELKheaevtnykiklEMLEKEKN-AVLDRMAESQEAELERLRTQlLFSHEEELSKL 640
Cdd:COG4913    734 DRLEAAEDLARLELRALLE------------ERFAAALGdAVERELRENLEERIDALRAR-LNRAEEELERA 792
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2163-2398 1.83e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 1.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2163 LEEQLEQFREELENK----NEEVQQLHMQLEiqkkESTTRLQELEQENKLFkDDMEKLGLAIKESDAVSTQdqhvlfgkf 2238
Cdd:COG3206    162 LEQNLELRREEARKAleflEEQLPELRKELE----EAEAALEEFRQKNGLV-DLSEEAKLLLQQLSELESQ--------- 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2239 aqiIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSD-QECVKRNREE--EIEQLNEVIEKLQ 2315
Cdd:COG3206    228 ---LAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAElAELSARYTPNhpDVIALRAQIAALR 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2316 QELANIGQKTLVDAHSlpeEADSLKHQLDMVIAEKLALEQQVETtneemtftknilketnfkMNQLTQELFSLKRERESM 2395
Cdd:COG3206    305 AQLQQEAQRILASLEA---ELEALQAREASLQAQLAQLEARLAE------------------LPELEAELRRLEREVEVA 363


                   ...
gi 1622925520 2396 EKI 2398
Cdd:COG3206    364 REL 366
PRK12704 PRK12704
phosphodiesterase; Provisional
 2087-2208 1.90e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.47  E-value: 1.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2087 KEQLQRDIQERNEEIEKLEFRVRELEQALlvsadtfqkvedRKQFGAVEAKpelslEVQLQAERDAIDRKEKEITNLEEQ 2166
Cdd:PRK12704    70 RNEFEKELRERRNELQKLEKRLLQKEENL------------DRKLELLEKR-----EEELEKKEKELEQKQQELEKKEEE 132

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622925520 2167 LEQFREELENKNEEVQQL------HMQLEIQKKESTT----RLQELEQENKL 2208
Cdd:PRK12704   133 LEELIEEQLQELERISGLtaeeakEILLEKVEEEARHeaavLIKEIEEEAKE 184
PRK11281 PRK11281
mechanosensitive channel MscK;
521-783 2.11e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 2.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  521 EEKCALQRQLE---DLFEELSFSREQIQRARQTIAEQESKLNEAQKSLstvEDLKAEIVSASESRKElelkheaevtnyK 597
Cdd:PRK11281    56 AEDKLVQQDLEqtlALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAEL---EALKDDNDEETRETLS------------T 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  598 IKLEMLEKEKNAVLDRMAESQEA------ELERLRTQLlfshEEELSKLKEDLEIEHQINIeKLKDNlgihykqQIDGLQ 671
Cdd:PRK11281   121 LSLRQLESRLAQTLDQLQNAQNDlaeynsQLVSLQTQP----ERAQAALYANSQRLQQIRN-LLKGG-------KVGGKA 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  672 NEMSQKIEtMQFEKD--NLITKQNQLILEISklkDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKgtleqevqelq 749
Cdd:PRK11281   189 LRPSQRVL-LQAEQAllNAQNDLQRKSLEGN---TQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSK----------- 253

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1622925520  750 lKIELLEKQMKEKENdlQEKfTQLEAENSILKDE 783
Cdd:PRK11281   254 -RLTLSEKTVQEAQS--QDE-AARIQANPLVAQE 283
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1580-2050 2.27e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1580 RQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHmRQMERQREDQEQLQEEIKRLNKQLAQ--------NGNENQGEAE 1651
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELE-EELEELEEELEEAEEELEEAEAELAEaeealleaEAELAEAEEE 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1652 EQTFKEKELDRKPEHvppEILSNERYALQKANNRLLKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAE 1731
Cdd:COG1196    381 LEELAEELLEALRAA---AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1732 ASVKSCVHEEHTRVTDESIPSYSGSDMPRNDinmwsKVTEEGTELSQRLVRSGFAGTEIDPENEELVLNISSRLQ----- 1806
Cdd:COG1196    458 EEALLELLAELLEEAALLEAALAELLEELAE-----AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAvligv 532

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1807 -AAVEKLLEAISETSSQLEHAKVTQTELMRESF--RQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYA 1883
Cdd:COG1196    533 eAAYEAALEAALAAALQNIVVEDDEVAAAAIEYlkAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1884 DEKTLFERQIQEKTDIIDRLEQEllcasNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEV 1963
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAA-----LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1964 QCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAIDREHE---RDVFQQ 2040
Cdd:COG1196    688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdLEELER 767

                          490
                   ....*....|
gi 1622925520 2041 EIQKLEQQLK 2050
Cdd:COG1196    768 ELERLEREIE 777
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 525-776 2.42e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  525 ALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLstvEDLKAEIVSASESRKELElkheAEVTNYKIKLEMLE 604
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL---AALERRIAALARRIRALE----QELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  605 KEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKedleieHQINIEKLKDNLgihykQQIDGLQNEMSQKIETMQFE 684
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLL------SPEDFLDAVRRL-----QYLKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  685 KDNLITKQNQLILEISKLKDLQQslvnskseemtlqinELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKEN 764
Cdd:COG4942    159 LAELAALRAELEAERAELEALLA---------------ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                          250
                   ....*....|..
gi 1622925520  765 DLQEKFTQLEAE 776
Cdd:COG4942    224 ELEALIARLEAE 235
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 482-645 2.55e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 2.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  482 TVNEDQIKLMNVAinELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEA 561
Cdd:COG1579      1 AMPEDLRALLDLQ--ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  562 QKSLSTV------EDLKAEIVSASESRKELElKHEAEVTNykiKLEMLEKEKNAVLDRMAEsQEAELERLRTQLlfshEE 635
Cdd:COG1579     79 EEQLGNVrnnkeyEALQKEIESLKRRISDLE-DEILELME---RIEELEEELAELEAELAE-LEAELEEKKAEL----DE 149

                          170
                   ....*....|
gi 1622925520  636 ELSKLKEDLE 645
Cdd:COG1579    150 ELAELEAELE 159
COG5022 COG5022
Myosin heavy chain [General function prediction only];
209-843 2.63e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.38  E-value: 2.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  209 QLTANLQQARREKDETMREFLELTEQSQKlqiQFQQLQASETLRNSthsstAADLLQAKQQIRTHQQQLEEQDHL-LEDY 287
Cdd:COG5022    831 KLRETEEVEFSLKAEVLIQKFGRSLKAKK---RFSLLKKETIYLQS-----AQRVELAERQLQELKIDVKSISSLkLVNL 902

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  288 QKKKE--DFTMQIS---FLQEKIKVYEMEQDKKV-ENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGE 361
Cdd:COG5022    903 ELESEiiELKKSLSsdlIENLEFKTELIARLKKLlNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTI 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  362 LQEQVVQKNQEIKNMKLELTN-SKQKER--QSSEEIKQLMGTVEELQKRNHKDSQfETDIVQRMeqetqRKLEQLRAELD 438
Cdd:COG5022    983 LVREGNKANSELKNFKKELAElSKQYGAlqESTKQLKELPVEVAELQSASKIISS-ESTELSIL-----KPLQKLKGLLL 1056

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  439 EMYGQQIVQMKQELIRQHVSQMEELKTRHKGEMENALRS--YPNITVNEDQikLMNVAINELNIKLQDTNSQKEKLKEEL 516
Cdd:COG5022   1057 LENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTinVKDLEVTNRN--LVKPANVLQFIVAQMIKLNLLQEISKF 1134

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  517 GVIL--------EEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQK-----SLSTVEDLKAEIVS-ASESR 582
Cdd:COG5022   1135 LSQLvntlepvfQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDeksklSSSEVNDLKNELIAlFSKIF 1214

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  583 KELELKHE-----AEVTNYKIKLEMLeKEKNAVLDRMAESQEAELERLRTQLLfSHEEELSKLKEDLEIEHQInieklkd 657
Cdd:COG5022   1215 SGWPRGDKlkkliSEGWVPTEYSTSL-KGFNNLNKKFDTPASMSNEKLLSLLN-SIDNLLSSYKLEEEVLPAT------- 1285

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  658 nlgihykqqidglQNEMSQKIETMQFekDNLITKQNQLILEISKLKDLQQSLVNSKSEEMtlQINELQKEIEILRQEEKE 737
Cdd:COG5022   1286 -------------INSLLQYINVGLF--NALRTKASSLRWKSATEVNYNSEELDDWCREF--EISDVDEELEELIQAVKV 1348

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  738 KGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDM-----LKIHTPDNQEERLIFIDSIKSK 812
Cdd:COG5022   1349 LQLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLPKEILKKIEALlikqeLQLSLEGKDETEVHLSEIFSEE 1428

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1622925520  813 ----SKDSVWEKEIEILTEENEDLKQQCIQLNEEI 843
Cdd:COG5022   1429 ksliSLDRNSIYKEEVLSSLSALLTKEKIALLDRK 1463
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 199-381 2.78e-04

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 46.77  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  199 AIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQL-QASETLRNSTHSstaadLLQAKQQIRTHQQQL 277
Cdd:pfam09726  396 ALVRLEQDIKKLKAELQASRQTEQELRSQISSLTSLERSLKSELGQLrQENDLLQTKLHN-----AVSAKQKDKQTVQQL 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  278 E-----EQDH-------LLEDYQKKKE----------------------------DFTMQISFLQEKIKVYEmEQDKKVE 317
Cdd:pfam09726  471 EkrlkaEQEArasaekqLAEEKKRKKEeeataaravalaaasrgecteslkqrkrELESEIKKLTHDIKLKE-EQIRELE 549

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  318 NSNKE--EIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKL-------LGE-------LQEQVVQKNQEIKNMKLELT 381
Cdd:pfam09726  550 IKVQElrKYKESEKDTEVLMSALSAMQDKNQHLENSLSAETRIkldlfsaLGDakrqleiAQGQIYQKDQEIKDLKQKIA 629
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
309-770 2.80e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 2.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  309 EMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLG--ELQEQVVQKNQEIKNMKLELTNSKQK 386
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  387 ErqssEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEmygqqiVQMKQELIRQHVSQMEELKTR 466
Cdd:COG4717    155 L----EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE------LQQRLAELEEELEEAQEELEE 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  467 HKGEMENALRSYPNITVNE--DQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQI 544
Cdd:COG4717    225 LEEELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  545 QRARQTIAE---QESKLNEAQKSLSTVEDLKAEIVSASESRKE--LELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQE 619
Cdd:COG4717    305 EELQALPALeelEEEELEELLAALGLPPDLSPEELLELLDRIEelQELLREAEELEEELQLEELEQEIAALLAEAGVEDE 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  620 AELERLRTQLlfsheEELSKLKEDL-EIEHQIN--IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLI 696
Cdd:COG4717    385 EELRAALEQA-----EEYQELKEELeELEEQLEelLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELE 459

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  697 LEISKLKDLQqslvnskseemtlQINELQKEIEILRQEEKEkgtLEQEVQELQLKIELLEKQMKEKENDLQEKF 770
Cdd:COG4717    460 AELEQLEEDG-------------ELAELLQELEELKAELRE---LAEEWAALKLALELLEEAREEYREERLPPV 517
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1939-2324 2.96e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1939 KAEAGPVEQ-----QLLQETEKLMKEKLEVQCQAEKVRDDL----------QKQVKALEIDVEEQVSRFIELEQEKNAEL 2003
Cdd:PRK02224   199 KEEKDLHERlngleSELAELDEEIERYEEQREQARETRDEAdevleeheerREELETLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2004 MDLRQQNQALEKQLEKMRKFLDEQAIDR------EHERDVFQQEI----QKLEQQLKVVPRFQPISEHQTREVEQLTNHL 2073
Cdd:PRK02224   279 EEVRDLRERLEELEEERDDLLAEAGLDDadaeavEARREELEDRDeelrDRLEECRVAAQAHNEEAESLREDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2074 KEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFgAVEAKPEL-----SLEVQLQA 2148
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEE-LREERDELrereaELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2149 ERDAIDRKEK---------------------EITNLEEQLEQFREELENKNEEVQQLHMQLEIQK--KESTTRLQELEQE 2205
Cdd:PRK02224   438 ARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2206 nklfKDDMEKLgLAIKESdavstqdqhvlfgkfaqIIQEKEVEIDQLNEQIMKL-----QQQLKITTDNKVIEEKNELIR 2280
Cdd:PRK02224   518 ----REDLEEL-IAERRE-----------------TIEEKRERAEELRERAAELeaeaeEKREAAAEAEEEAEEAREEVA 575

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1622925520 2281 DLETQIECLMSDQECVKRNRE--EEIEQLNEVIEKLQQELANIGQK 2324
Cdd:PRK02224   576 ELNSKLAELKERIESLERIRTllAAIADAEDEIERLREKREALAEL 621
mukB PRK04863
chromosome partition protein MukB;
1931-2261 3.59e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.87  E-value: 3.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1931 LSRQKEAMKAEAGPVEQQLLQETEKL--MKEKLEVQCQAEKVRDDLQKqvkaLEIDVEEQVsrfiELEQEKNAELMDLRQ 2008
Cdd:PRK04863   312 MARELAELNEAESDLEQDYQAASDHLnlVQTALRQQEKIERYQADLEE----LEERLEEQN----EVVEEADEQQEENEA 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2009 QNQALEKQLEKMRKFLD--EQAIDREHERDV-FQQEIQKLE--QQLKVVPRFQPisEHQTREVEQLTNHLKEKTDKcsel 2083
Cdd:PRK04863   384 RAEAAEEEVDELKSQLAdyQQALDVQQTRAIqYQQAVQALEraKQLCGLPDLTA--DNAEDWLEEFQAKEQEATEE---- 457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2084 LLSKEQLQRDIQERNEEIEKLEFRVREL------EQALLVSADTF-QKVEDRKQFGAVEA-KPELS-LEVQLQAERDAID 2154
Cdd:PRK04863   458 LLSLEQKLSVAQAAHSQFEQAYQLVRKIagevsrSEAWDVARELLrRLREQRHLAEQLQQlRMRLSeLEQRLRQQQRAER 537

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2155 R-------------KEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQ---ENKLFKDDMEKL-- 2216
Cdd:PRK04863   538 LlaefckrlgknldDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAArapAWLAAQDALARLre 617

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622925520 2217 --GLAIKESDAVSTQDQHVLFGKFAQIIQEKEVE--IDQLNEQIMKLQQ 2261
Cdd:PRK04863   618 qsGEEFEDSQDVTEYMQQLLERERELTVERDELAarKQALDEEIERLSQ 666
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1946-2397 3.74e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 3.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1946 EQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEiDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLD 2025
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2026 EQAIDRE-----HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKCS--------ELLLSKEQLQR 2092
Cdd:COG4717    127 LLPLYQElealeAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlateeelqDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2093 DIQERNEEIEKLEFRVRELEQAL------LVSADTFQKVEDRKQFGAVEAkPELSLEVQLQAERDAIDRKEKEITNLEEQ 2166
Cdd:COG4717    207 RLAELEEELEEAQEELEELEEELeqleneLEAAALEERLKEARLLLLIAA-ALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2167 LEQFREELENKNEEVQQlhmqlEIQKKESTTRLQELEQENklFKDDMEKLGLAIKESDAvstqdqhvlfgkFAQIIQEKE 2246
Cdd:COG4717    286 LALLFLLLAREKASLGK-----EAEELQALPALEELEEEE--LEELLAALGLPPDLSPE------------ELLELLDRI 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2247 VEIDQLNEQIMKLQQQLKIttdnkvieekneliRDLETQIECLMSDQECvkrnreEEIEQLNEVIEKLQQELANIGQKTL 2326
Cdd:COG4717    347 EELQELLREAEELEEELQL--------------EELEQEIAALLAEAGV------EDEEELRAALEQAEEYQELKEELEE 406

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 2327 VDaHSLPEEADSLKHQLDMVIAEklALEQQVETTNEEmtftkniLKETNFKMNQLTQELFSLKRERESMEK 2397
Cdd:COG4717    407 LE-EQLEELLGELEELLEALDEE--ELEEELEELEEE-------LEELEEELEELREELAELEAELEQLEE 467
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2143-2319 3.97e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 3.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2143 EVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGlaike 2222
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELG----- 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2223 SDAVSTQDQHVLFGKFAQIIQEKEVE--IDQLN--EQIMKLQQQL--KITTDNKVIEEKNELIRDLETQIECLMSDQECV 2296
Cdd:COG3883     90 ERARALYRSGGSVSYLDVLLGSESFSdfLDRLSalSKIADADADLleELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                          170       180
                   ....*....|....*....|...
gi 1622925520 2297 KRNREEEIEQLNEVIEKLQQELA 2319
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEA 192
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
260-561 3.98e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  260 AADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEqdkkvensnkEEIQEKEtiieelntkii 339
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAE----------REIAELE----------- 674

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  340 eeekktlELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQkrnhkdsqfetdiv 419
Cdd:COG4913    675 -------AELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ-------------- 733

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  420 QRMEQETQRKLEQLRAELDEMYGQ----QIVQMKQELIRQHVSQMEELKTRHKGEMENALRSY----PNITVNEDqIKLM 491
Cdd:COG4913    734 DRLEAAEDLARLELRALLEERFAAalgdAVERELRENLEERIDALRARLNRAEEELERAMRAFnrewPAETADLD-ADLE 812

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520  492 NVA--INELNiKLQDTN--SQKEKLKEelgvileekcALQRQLEDLFEELSFsreQIQRARQTIAEQESKLNEA 561
Cdd:COG4913    813 SLPeyLALLD-RLEEDGlpEYEERFKE----------LLNENSIEFVADLLS---KLRRAIREIKERIDPLNDS 872
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 147-475 4.01e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.50  E-value: 4.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  147 EQGAQYSLTHLEMMESELAgkQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTanlqqarrEKDETMR 226
Cdd:TIGR00618  638 SQELALKLTALHALQLTLT--QERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLA--------QCQTLLR 707

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  227 EFLELTEQSQKlqiQFQQLQASETLRNSThsstaadllqAKQQIRTHQQQLEEQDHLlEDYQKKKEDFTMQISFLQEKIK 306
Cdd:TIGR00618  708 ELETHIEEYDR---EFNEIENASSSLGSD----------LAAREDALNQSLKELMHQ-ARTVLKARTEAHFNNNEEVTAA 773

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  307 VYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQ-------EIKNMKLE 379
Cdd:TIGR00618  774 LQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEeksatlgEITHQLLK 853

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  380 LTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAeldemygqqivqmKQELIRQHVSQ 459
Cdd:TIGR00618  854 YEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLA-------------NQSEGRFHGRY 920

                          330
                   ....*....|....*.
gi 1622925520  460 MEELKTRHKGEMENAL 475
Cdd:TIGR00618  921 ADSHVNARKYQGLALL 936
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1803-2104 4.15e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 4.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1803 SRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEgvIDGY 1882
Cdd:TIGR02169  719 GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEI 796

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1883 ADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLE 1962
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAA 876

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1963 VQcQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER-----DV 2037
Cdd:TIGR02169  877 LR-DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEeelslED 955

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520 2038 FQQEIQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKcsellLSKEqlQRDIQERNEEIEKL 2104
Cdd:TIGR02169  956 VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAK-----LEEE--RKAILERIEEYEKK 1015
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 197-594 4.25e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 4.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  197 EAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQasETLRNSTHSSTAADLlQAKQQIRTHQQQ 276
Cdd:pfam07888   37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELK--EELRQSREKHEELEE-KYKELSASSEEL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  277 LEEQDHLL---EDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQ--EKETIIEELNTKIIEEEKKTLELKDK 351
Cdd:pfam07888  114 SEEKDALLaqrAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQrkEEEAERKQLQAKLQQTEEELRSLSKE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  352 LTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQE--TQRK 429
Cdd:pfam07888  194 FQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRdrTQAE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  430 LEQLRAELDEMYGQqivqmkqelIRQHVSQMEELKTRHKGEMENALRsypNITVNEDQIKLMNVAINELNIKLQDTNSQK 509
Cdd:pfam07888  274 LHQARLQAAQLTLQ---------LADASLALREGRARWAQERETLQQ---SAEADKDRIEKLSAELQRLEERLQEERMER 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  510 EKLKEELGvileekcalqrqledlfEELSFSREQIQRARQTIAEQESKLNEAQKSlstVEDLKAEIVSASESRKELELKH 589
Cdd:pfam07888  342 EKLEVELG-----------------REKDCNRVQLSESRRELQELKASLRVAQKE---KEQLQAEKQELLEYIRQLEQRL 401


                   ....*
gi 1622925520  590 EAEVT 594
Cdd:pfam07888  402 ETVAD 406
PRK12704 PRK12704
phosphodiesterase; Provisional
 555-738 4.59e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.92  E-value: 4.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  555 ESKLNEAQKSL-STVEDLKAEivsASESRKELELKHEAEVTNYKIKLEMLEKEKNavldrmaesqeAELERLRTQLLfSH 633
Cdd:PRK12704    30 EAKIKEAEEEAkRILEEAKKE---AEAIKKEALLEAKEEIHKLRNEFEKELRERR-----------NELQKLEKRLL-QK 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  634 EEELSKLKEDLEIEHQInIEKLKDNLgihykqqidglqNEMSQKIETMQFEKDNLITKQNQLILEISKL--KDLQQSLVN 711
Cdd:PRK12704    95 EENLDRKLELLEKREEE-LEKKEKEL------------EQKQQELEKKEEELEELIEEQLQELERISGLtaEEAKEILLE 161

                          170       180
                   ....*....|....*....|....*..
gi 1622925520  712 SKSEEMTLQINELQKEIEILRQEEKEK 738
Cdd:PRK12704   162 KVEEEARHEAAVLIKEIEEEAKEEADK 188
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1966-2205 5.02e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.16  E-value: 5.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1966 QAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNaeLMDLRQQNQALEKQLEKmrkfLDEQAIDREHERDVFQQEIQKL 2045
Cdd:COG3206    172 EARKALEFLEEQLPELRKELEEAEAALEEFRQKNG--LVDLSEEAKLLLQQLSE----LESQLAEARAELAEAEARLAAL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2046 EQQLKVVPRFQPiSEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSadtfqkv 2125
Cdd:COG3206    246 RAQLGSGPDALP-ELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAS------- 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2126 edrkqfgaveakpelslevqLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTT---RLQEL 2202
Cdd:COG3206    318 --------------------LEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESllqRLEEA 377


                   ...
gi 1622925520 2203 EQE 2205
Cdd:COG3206    378 RLA 380
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 677-783 5.19e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 5.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  677 KIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLE 756
Cdd:COG0542    405 EIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRY 484

                           90       100
                   ....*....|....*....|....*..
gi 1622925520  757 KQMKEKENDLQEKFTQLEAENSILKDE 783
Cdd:COG0542    485 GKIPELEKELAELEEELAELAPLLREE 511
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1950-2401 5.23e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.19  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1950 LQETEKLMKEKlevqcqaEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAI 2029
Cdd:TIGR00606  711 LKSTESELKKK-------EKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEES 783

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2030 DREHERDVfqQEIQKLEQQLKVVPR--FQPISEHQT----REVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEK 2103
Cdd:TIGR00606  784 AKVCLTDV--TIMERFQMELKDVERkiAQQAAKLQGsdldRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH 861

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2104 LEFRVRELEQALLVSADTFQKvedRKQFGavEAKPELSLEVQlqaerdAIDRKEKEITNLEEQLEQFREELENKNEEvqq 2183
Cdd:TIGR00606  862 LKSKTNELKSEKLQIGTNLQR---RQQFE--EQLVELSTEVQ------SLIREIKDAKEQDSPLETFLEKDQQEKEE--- 927

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2184 LHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQL 2263
Cdd:TIGR00606  928 LISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI 1007

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2264 KITTDNKVIEEKNELIRDLETQIECLMSD-QECVKRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKH- 2341
Cdd:TIGR00606 1008 DTQKIQERWLQDNLTLRKRENELKEVEEElKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHf 1087

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2342 QLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELfsLKRERESMEKIQSI 2401
Cdd:TIGR00606 1088 KKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAI--MKFHSMKMEEINKI 1145
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 3038-3317 6.01e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 6.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3038 QKADRRSLLSEIQALHAQMNGRKITLKR-EQENEKSSQEL--LEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKM 3114
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRiENRLDELSQELsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3115 VVAELRSELAQTKLELETTLKAQHKHLKELEAF-----RLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLgHS 3189
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK-EY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3190 EERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLESEKVRIREMSS 3269
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3270 TLDRERELHAQLQSNDGTGQSR------------PSLPSEDLLKELQKQLEEKHSRIVEL 3317
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEElseiedpkgedeEIPEEELSLEDVQAELQRVEEEIRAL 970
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1789-2318 6.38e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 6.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1789 EIDPENEELVLNISSRLQAaVEKLLEAISETSSQLEHAKVTQTELmresfRQKQEATESLKCQEDLRERLHEEsraREQL 1868
Cdd:PRK03918   235 ELKEEIEELEKELESLEGS-KRKLEEKIRELEERIEELKKEIEEL-----EEKVKELKELKEKAEEYIKLSEF---YEEY 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1869 AVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQ--ELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVE 1946
Cdd:PRK03918   306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEElkKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1947 -QQLLQETEKLMKEKLEVQCQAEKVRD---DLQKQVKALEIDVEEQVS---------RFIELEQEKN------AELMDLR 2007
Cdd:PRK03918   386 pEKLEKELEELEKAKEEIEEEISKITArigELKKEIKELKKAIEELKKakgkcpvcgRELTEEHRKElleeytAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2008 QQNQALEKQLEKMRKFLDEQAIDREHERDVFQQ-----EIQKLEQQLKVVPRFQpiSEHQTREVEQLTNH---------- 2072
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKESELIKLkelaeQLKELEEKLKKYNLEE--LEKKAEEYEKLKEKliklkgeiks 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2073 LKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELeqallvSADTFQKVEDRKQfgavEAKPELSLEVQLQAERDA 2152
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL------GFESVEELEERLK----ELEPFYNEYLELKDAEKE 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2153 IDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTtrlqelEQENKLFKDDMEKLGLAikesdavstqdqh 2232
Cdd:PRK03918   614 LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS------EEEYEELREEYLELSRE------------- 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2233 vLFGKFAQiIQEKEVEIDQLNEQIMKLQQQLkittdnKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 2312
Cdd:PRK03918   675 -LAGLRAE-LEELEKRREEIKKTLEKLKEEL------EEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVG 746


                   ....*.
gi 1622925520 2313 KLQQEL 2318
Cdd:PRK03918   747 EIASEI 752
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 505-803 7.12e-04

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 45.62  E-value: 7.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  505 TNSQKEKLKEELGVILEE---KCALQRQLEDLFEELSFSREQIQRARQTIAEQESKL-NEAQKSLSTV---EDLKAEI-- 575
Cdd:PLN03229   460 LNEMIEKLKKEIDLEYTEaviAMGLQERLENLREEFSKANSQDQLMHPVLMEKIEKLkDEFNKRLSRApnyLSLKYKLdm 539

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  576 -VSASESRKELELKHEAEV----TNYKIKLEMLE---KEKNAVLDRMAESQEA------------ELERLRTQLLFSHEE 635
Cdd:PLN03229   540 lNEFSRAKALSEKKSKAEKlkaeINKKFKEVMDRpeiKEKMEALKAEVASSGAssgdeldddlkeKVEKMKKEIELELAG 619

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  636 ELSKLKEDLEIEHQINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDnLITKQNQLILEISKlkdlqqslvNSKSE 715
Cdd:PLN03229   620 VLKSMGLEVIGVTKKNKDTAEQTPPPNLQEKIESLNEEINKKIERVIRSSD-LKSKIELLKLEVAK---------ASKTP 689

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  716 EMTLQinelqKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDlqekftqLEAENSILKdekkalEDMLKIHT 795
Cdd:PLN03229   690 DVTEK-----EKIEALEQQIKQKIAEALNSSELKEKFEELEAELAAARET-------AAESNGSLK------NDDDKEED 751


                   ....*...
gi 1622925520  796 PDNQEERL 803
Cdd:PLN03229   752 SKEDGSRV 759
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 227-784 7.20e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.87  E-value: 7.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  227 EFLELTEQSQKLQIQFQQLQASETLRNSTHSSTA-ADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKI 305
Cdd:pfam05483  222 EKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKmKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  306 KVyEMEQDKKVENSNKEEIQ-----------EKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIK 374
Cdd:pfam05483  302 KM-SLQRSMSTQKALEEDLQiatkticqlteEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLK 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  375 NMKLELTNSKQKERQSSE-------EIKQLMGTVEELQKRNHKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQI 445
Cdd:pfam05483  381 IITMELQKKSSELEEMTKfknnkevELEELKKILAEDEKLLDEKKQFEkiAEELKGKEQELIFLLQAREKEIHDLEIQLT 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  446 VQMKQEliRQHVSQMEELKTrhkgEMENALRSYPNITVNEDQIKLMNvaiNELNIKLQDTNSQKEKLKEELGVILEEKCA 525
Cdd:pfam05483  461 AIKTSE--EHYLKEVEDLKT----ELEKEKLKNIELTAHCDKLLLEN---KELTQEASDMTLELKKHQEDIINCKKQEER 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  526 LQRQLEDLFEELSFSREQIQRARQTIAEQESKLN-EAQKSLSTVEDLKAEIVSASESRKELELK---HEAEVTNYKIKLE 601
Cdd:pfam05483  532 MLKQIENLEEKEMNLRDELESVREEFIQKGDEVKcKLDKSEENARSIEYEVLKKEKQMKILENKcnnLKKQIENKNKNIE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  602 MLEKEKNAVLDR-MAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDNlgihykqqidglQNEMSQKIET 680
Cdd:pfam05483  612 ELHQENKALKKKgSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKIS------------EEKLLEEVEK 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  681 MQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKE----KGTLEQEVQELQLKIELLE 756
Cdd:pfam05483  680 AKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEqssaKAALEIELSNIKAELLSLK 759

                          570       580
                   ....*....|....*....|....*....
gi 1622925520  757 KQMkEKENDLQEKFTQLEAENS-ILKDEK 784
Cdd:pfam05483  760 KQL-EIEKEEKEKLKMEAKENTaILKDKK 787
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 158-989 7.27e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.94  E-value: 7.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  158 EMMESELAGKQHEIEELNRELEEmRVTYGTEGLQQLQEFEAAIKQRdgiITQLTANLqqarrEKDETMREFLELTEQSqk 237
Cdd:pfam01576   60 EEMRARLAARKQELEEILHELES-RLEEEEERSQQLQNEKKKMQQH---IQDLEEQL-----DEEEAARQKLQLEKVT-- 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  238 LQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVE 317
Cdd:pfam01576  129 TEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEK 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  318 NSNK---------EEIQEKETIIEELNTKIIEEEKKTLELKDKL-------TAADKLLGELQEQVVQKNQEIKNMKLELT 381
Cdd:pfam01576  209 AKRKlegestdlqEQIAELQAQIAELRAQLAKKEEELQAALARLeeetaqkNNALKKIRELEAQISELQEDLESERAARN 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  382 NSKQKERQSSEEIKQLMGTVEelqkrnhkDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMkQELIRQHVSQME 461
Cdd:pfam01576  289 KAEKQRRDLGEELEALKTELE--------DTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQL-QEMRQKHTQALE 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  462 ELKTrhkgEMENALRSYPNITVN----EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEEL 537
Cdd:pfam01576  360 ELTE----QLEQAKRNKANLEKAkqalESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKL 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  538 SFSREQIQRARQTIAEQESKLNEAQKSLSTVEdlkaeivSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Cdd:pfam01576  436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLE-------SQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEE 508

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  618 QEAEleRLRTQLLFSHEEELSKLKEDLEiEHQINIEKLKDNLGiHYKQQIDGLQNEMSQKIET----------MQFEKDN 687
Cdd:pfam01576  509 EEAK--RNVERQLSTLQAQLSDMKKKLE-EDAGTLEALEEGKK-RLQRELEALTQQLEEKAAAydklektknrLQQELDD 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  688 LITKQNQLILEISKLKDLQQSLVNSKSEEMTLQiNELQKEIEILRQEEKEKGT----LEQEVQELQLKIELLEKQMKEKE 763
Cdd:pfam01576  585 LLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAIS-ARYAEERDRAEAEAREKETralsLARALEEALEAKEELERTNKQLR 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  764 NDLQEKFTQ-----------------LEAENSILKDEKKALEDMLKIhTPDNQEERLIFIDSIKSKskdsvWEKEIEILT 826
Cdd:pfam01576  664 AEMEDLVSSkddvgknvhelerskraLEQQVEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKAQ-----FERDLQARD 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  827 EENEDLKQQCIQLNEEIE-------KQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDledsKNKQELEYKSKLKALNEE 899
Cdd:pfam01576  738 EQGEEKRRQLVKQVRELEaelederKQRAQAVAAKKKLELDLKELEAQIDAANKGREE----AVKQLKKLQAQMKDLQRE 813

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  900 LHLQRINPTTVKTKSSVFDED-KTFVAETLEMGE----------VVEKDTTELMEKL-------EVTKREKLELSQRLAD 961
Cdd:pfam01576  814 LEEARASRDEILAQSKESEKKlKNLEAELLQLQEdlaaserarrQAQQERDELADEIasgasgkSALQDEKRRLEARIAQ 893

                          890       900
                   ....*....|....*....|....*...
gi 1622925520  962 LSEQLKQKHGEISFLNEEVKSLKQEKEQ 989
Cdd:pfam01576  894 LEEELEEEQSNTELLNDRLRKSTLQVEQ 921
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1813-2265 8.02e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 8.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1813 LEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDgyadektlfeRQ 1892
Cdd:pfam15921  460 LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVD----------LK 529

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1893 IQEKtdiidrleqellcasnrlqeleaeqqqiqeerellsrqkeamkaeagpveQQLLQETEKLMkeklEVQCQAEKVRD 1972
Cdd:pfam15921  530 LQEL--------------------------------------------------QHLKNEGDHLR----NVQTECEALKL 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1973 DLQKQVKALEIdVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDE--------QAIDREHERDVFQQEIQK 2044
Cdd:pfam15921  556 QMAEKDKVIEI-LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkDAKIRELEARVSDLELEK 634

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2045 LEQQLKVVPRFQPISEHQtREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIE----KLEFRVRELEQALLVSAD 2120
Cdd:pfam15921  635 VKLVNAGSERLRAVKDIK-QERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnKLKMQLKSAQSELEQTRN 713

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2121 TFQKVEDRKQFGaveAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQ 2200
Cdd:pfam15921  714 TLKSMEGSDGHA---MKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAG 790

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520 2201 ELE----QENKLfKDDMEKLGLAIkesDAVSTQdqhvlFGKFAQIIQEKEVEIDQLneqimKLQQQLKI 2265
Cdd:pfam15921  791 ELEvlrsQERRL-KEKVANMEVAL---DKASLQ-----FAECQDIIQRQEQESVRL-----KLQHTLDV 845
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
155-468 8.15e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 8.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  155 THLEMMESELAGKQHEIEELNRELEEMRVTYG--TEGLQQLQEF-EAAIKQRDGI---ITQLTANLQQA--RREKDETMR 226
Cdd:PRK02224   370 SELEEAREAVEDRREEIEELEEEIEELRERFGdaPVDLGNAEDFlEELREERDELrerEAELEATLRTAreRVEEAEALL 449

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  227 E-------------------FLELTEQSQKLQIQFQQLQASETLRNSTHSStAADLLQAKQQIRTHQQQLEEQDHLLEDY 287
Cdd:PRK02224   450 EagkcpecgqpvegsphvetIEEDRERVEELEAELEDLEEEVEEVEERLER-AEDLVEAEDRIERLEERREDLEELIAER 528

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  288 QKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK--EEIQEKETIIEELNTKiIEEEKKTLELKDKLTAADKLLGELQEQ 365
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEAEAEEKREAAAEaeEEAEEAREEVAELNSK-LAELKERIESLERIRTLLAAIADAEDE 607

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  366 VVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE--LQKRNHKDSQFETDIVQRMEqetqrKLEQLRAELDEmygq 443
Cdd:PRK02224   608 IERLREKREALAELNDERRERLAEKRERKRELEAEFDEarIEEAREDKERAEEYLEQVEE-----KLDELREERDD---- 678

                          330       340
                   ....*....|....*....|....*
gi 1622925520  444 qiVQMKQELIRQHVSQMEELKTRHK 468
Cdd:PRK02224   679 --LQAEIGAVENELEELEELRERRE 701
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 157-628 8.50e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 8.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  157 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGlQQLQEFEAAIKQRDgiiTQLTANLQQARREKDETMREFLELTEQSQ 236
Cdd:pfam15921  344 IEELEKQLVLANSELTEARTERDQFSQESGNLD-DQLQKLLADLHKRE---KELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  237 KLQIQFQQLQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVyeMEQDKKV 316
Cdd:pfam15921  420 ELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMT--LESSERT 497

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  317 ENSNKEEIQEKETIIEELNTKI----------IEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQK 386
Cdd:pfam15921  498 VSDLTASLQEKERAIEATNAEItklrsrvdlkLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQL 577

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  387 ERQSSEEIKQLMGTVEELQKRNHkDSQFETDIVQRMEQETQRKLEQLRAELDEM---------YGQQIVQMKQELIRQHV 457
Cdd:pfam15921  578 VGQHGRTAGAMQVEKAQLEKEIN-DRRLELQEFKILKDKKDAKIRELEARVSDLelekvklvnAGSERLRAVKDIKQERD 656

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  458 SQMEELKTRhKGEMENALRSYPNITVN-EDQIKLMNVAINELNIKLQDTNSQKEKLKEEL-------GVILEEKCALQRQ 529
Cdd:pfam15921  657 QLLNEVKTS-RNELNSLSEDYEVLKRNfRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQ 735

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  530 L-------EDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602
Cdd:pfam15921  736 ItakrgqiDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK 815

                          490       500
                   ....*....|....*....|....*.
gi 1622925520  603 LEKEKNAVLDrMAESQEAELERLRTQ 628
Cdd:pfam15921  816 ASLQFAECQD-IIQRQEQESVRLKLQ 840
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 612-796 8.87e-04

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 45.44  E-value: 8.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  612 DRMAESQEAeLERLRTQLLFSHEEELSKLKE--DLEIEHQI---NIEKLKDNLGIHyKQQIDGLQNEMSQKIETMqFEKD 686
Cdd:pfam13166  279 DEFTEFQNR-LQKLIEKVESAISSLLAQLPAvsDLASLLSAfelDVEDIESEAEVL-NSQLDGLRRALEAKRKDP-FKSI 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  687 NLITKQNqlilEISKLKDLQQSLVNS--KSEEMTLQINELQKE-IEILRQEEKEKgtLEQEVQELQLKIELLEKQMkeke 763
Cdd:pfam13166  356 ELDSVDA----KIESINDLVASINELiaKHNEITDNFEEEKNKaKKKLRLHLVEE--FKSEIDEYKDKYAGLEKAI---- 425

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1622925520  764 NDLQEKFTQLEAENSILKDEKKALEDMLKIHTP 796
Cdd:pfam13166  426 NSLEKEIKNLEAEIKKLREEIKELEAQLRDHKP 458
PRK01156 PRK01156
chromosome segregation protein; Provisional
 151-787 8.97e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.28  E-value: 8.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  151 QYSLTHLEMMESELAGKQHEIEELNRELEEMrvtygtEGLQQLQEFEaaikqrdgiITQLTANLQQARREK---DETMRE 227
Cdd:PRK01156   179 RAEISNIDYLEEKLKSSNLELENIKKQIADD------EKSHSITLKE---------IERLSIEYNNAMDDYnnlKSALNE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  228 FLELTEQSQKLQIQFQQLQASetlrnsthsstaadlLQAKQQIRTHQQQLEEQDHLLEDYQ--KKKEDFTMQISFLQEKI 305
Cdd:PRK01156   244 LSSLEDMKNRYESEIKTAESD---------------LSMELEKNNYYKELEERHMKIINDPvyKNRNYINDYFKYKNDIE 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  306 KVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELkdkltaaDKLLGELQEQVVQKNQEIKNMKleltNSKQ 385
Cdd:PRK01156   309 NKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDL-------NNQILELEGYEMDYNSYLKSIE----SLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  386 KERQSSEEIKQLMGTVEELQKRNHKDSqfetDIVQRMEQETQRKLEQLRAELDEMygqqivQMKQELIRQHVSQMEElkt 465
Cdd:PRK01156   378 KIEEYSKNIERMSAFISEILKIQEIDP----DAIKKELNEINVKLQDISSKVSSL------NQRIRALRENLDELSR--- 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  466 rhKGEMENALRSYP--NITVNEDQIklmNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDL----FEELSF 539
Cdd:PRK01156   445 --NMEMLNGQSVCPvcGTTLGEEKS---NHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLeseeINKSIN 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  540 SREQIQRARQTIAEQESKLNEAqkslstvedlkaeivsasesrKELELKHEAEVTNYK-IKLEMLEKEKNAVLDRMAESQ 618
Cdd:PRK01156   520 EYNKIESARADLEDIKIKINEL---------------------KDKHDKYEEIKNRYKsLKLEDLDSKRTSWLNALAVIS 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  619 EAELERLRTQllfsHEEELSKLKEDLEIEHQINIEKLKDNLGI-HYKQQIDGLQNEMSQKIETMQFEK---DNLITKQNQ 694
Cdd:PRK01156   579 LIDIETNRSR----SNEIKKQLNDLESRLQEIEIGFPDDKSYIdKSIREIENEANNLNNKYNEIQENKiliEKLRGKIDN 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  695 LILEISKLKDLQQSL--VNSKSEEMTLQINELQKEIEILRQEEKEKgtlEQEVQELQLKIELLEKQMKEKENDLqEKFTQ 772
Cdd:PRK01156   655 YKKQIAEIDSIIPDLkeITSRINDIEDNLKKSRKALDDAKANRARL---ESTIEILRTRINELSDRINDINETL-ESMKK 730

                          650
                   ....*....|....*
gi 1622925520  773 LEAENSILKDEKKAL 787
Cdd:PRK01156   731 IKKAIGDLKRLREAF 745
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 189-898 9.59e-04

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 45.59  E-value: 9.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  189 GLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQ-LQASETLRNSTHSSTAADLLQAK 267
Cdd:PTZ00440   359 SLEMLSMLDSLLIKKEKILNNLFNKLFGDLKEKIETLLDSEYFISKYTNIISLSEHtLKAAEDVLKENSQKIADYALYSN 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  268 QQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFL-----QEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEE 342
Cdd:PTZ00440   439 LEIIEIKKKYDEKINELKKSINQLKTLISIMKSFydliiSEKDSMDSKEKKESSDSNYQEKVDELLQIINSIKEKNNIVN 518

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  343 KKTLELKDKLTAADKLLGEL-------------QEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNH 409
Cdd:PTZ00440   519 NNFKNIEDYYITIEGLKNEIeglielikyylqsIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDEIDNIIQ 598

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  410 KDSQFETDIVQRMEQET------QRKLEQLRAELDEMYGQQIVQMKQELIRQHVSQMEELKTrhKGEMENALrsyPNITV 483
Cdd:PTZ00440   599 QIEELINEALFNKEKFInekndlQEKVKYILNKFYKGDLQELLDELSHFLDDHKYLYHEAKS--KEDLQTLL---NTSKN 673

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  484 NEDQIKLMNVAINELNIKLQDTNSQKEK-LKEELgvileekcaLQRQLEDLFEELSFSREQIqraRQTIAEQESKLNEAQ 562
Cdd:PTZ00440   674 EYEKLEFMKSDNIDNIIKNLKKELQNLLsLKENI---------IKKQLNNIEQDISNSLNQY---TIKYNDLKSSIEEYK 741

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  563 KSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRmaesqeaelERLRTQLLFSHEEELSKLKE 642
Cdd:PTZ00440   742 EEEEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNTYEEFLQYKDTILNK---------ENKISNDINILKENKKNNQD 812

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  643 DLEiEHQINIEKLKDNLGIHYkQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILeisklkdlqqSLVNSKSEEMTLQIN 722
Cdd:PTZ00440   813 LLN-SYNILIQKLEAHTEKND-EELKQLLQKFPTEDENLNLKELEKEFNENNQIV----------DNIIKDIENMNKNIN 880

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  723 ELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKEND-LQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEE 801
Cdd:PTZ00440   881 IIKTLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDnIIQKNEKLNLLNNLNKEKEKIEKQLSDTKINNLKMQ 960

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  802 RLIFIDSIKsKSKDSVwEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLlkVKDDLEDS 881
Cdd:PTZ00440   961 IEKTLEYYD-KSKENI-NGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILNKKIDDLIKKQHDDIIEL--IDKLIKEK 1036

                          730
                   ....*....|....*..
gi 1622925520  882 KNKQELEYKSKLKALNE 898
Cdd:PTZ00440  1037 GKEIEEKVDQYISLLEK 1053
PTZ00121 PTZ00121
MAEBL; Provisional
 1814-2504 9.82e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 9.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1814 EAISETSSQLEHAKVTQTELMRESFRQKqeatESLKCQEDLRE----RLHEESRAREqlavELSKAEgvidgyADEKTLF 1889
Cdd:PTZ00121  1091 EATEEAFGKAEEAKKTETGKAEEARKAE----EAKKKAEDARKaeeaRKAEDARKAE----EARKAE------DAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1890 ERQIQEKTDI-IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEagpvEQQLLQETEKLMKE-KLEVQCQA 1967
Cdd:PTZ00121  1157 ARKAEDARKAeEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAE----EERKAEEARKAEDAkKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1968 EKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQAleKQLEKMRKFLDEQAID--REHERDVFQQEIQKL 2045
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADeaKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2046 EQQLKVVPRFQPISEHQTREVEQLTNHLKEKTdKCSELLLSKEQLQRDIQERNEEIEKlefrvreleqallvsADTFQKV 2125
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAK-KAAEAAKAEAEAAADEAEAAEEKAE---------------AAEKKKE 1374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2126 EDRKQFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHmqlEIQKKESTTRLQELEQE 2205
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD---EAKKKAEEAKKADEAKK 1451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2206 NKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEK---NELIRDL 2282
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAkkaDEAKKAE 1531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2283 ETQIECLMSDQECVKrnREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEADSLKHqldmviAEKLALEQQVETTNE 2362
Cdd:PTZ00121  1532 EAKKADEAKKAEEKK--KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK------AEEARIEEVMKLYEE 1603

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2363 EMTFTKNILK---ETNFKMNQLTQElfslKRERESMEKIQSIPGKSVNMAiDDMSKDKPELEVVLTEDALKSLENQTYLK 2439
Cdd:PTZ00121  1604 EKKMKAEEAKkaeEAKIKAEELKKA----EEEKKKVEQLKKKEAEEKKKA-EELKKAEEENKIKAAEEAKKAEEDKKKAE 1678

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2440 SF-----EENGKGSIINLETRLLQLESTVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEE 2504
Cdd:PTZ00121  1679 EAkkaeeDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
PTZ00121 PTZ00121
MAEBL; Provisional
 1817-2540 1.03e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1817 SETSSQLEHAKVTQTELMRESFRQKQEA--TESLKCQEDLRERLHEESRAREQLAVELSkaegvidgyadektlfeRQIQ 1894
Cdd:PTZ00121  1196 AEDARKAEAARKAEEERKAEEARKAEDAkkAEAVKKAEEAKKDAEEAKKAEEERNNEEI-----------------RKFE 1258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1895 EKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDL 1974
Cdd:PTZ00121  1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA 1338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1975 QKQVKALEIDVEEQVSRFIELEQ-EKNAELMDLRQQN-----QALEKQLEKMRKflDEQAIDREHERDVFQQEIQKLEQQ 2048
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAaEEKAEAAEKKKEEakkkaDAAKKKAEEKKK--ADEAKKKAEEDKKKADELKKAAAA 1416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2049 LKVVPRFQPISEhQTREVEQLTNHLKEKTdKCSELLLSKEQlqrdiQERNEEIEKLEFRVRELEQALlvsadtfQKVEDR 2128
Cdd:PTZ00121  1417 KKKADEAKKKAE-EKKKADEAKKKAEEAK-KADEAKKKAEE-----AKKAEEAKKKAEEAKKADEAK-------KKAEEA 1482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2129 KQFGAVEAKPELSLEVQLQAERDAIDRKEKEitNLEEQLEQFREELENKNEEVQQLHmqlEIQKKESTTRLQELEQENKL 2208
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEAKKKAD--EAKKAEEAKKADEAKKAEEAKKAD---EAKKAEEKKKADELKKAEEL 1557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2209 FKDDMEKlglaiKESDAVSTQDQHVLFGKFAQIIQEKEveiDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIEc 2288
Cdd:PTZ00121  1558 KKAEEKK-----KAEEAKKAEEDKNMALRKAEEAKKAE---EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA- 1628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2289 lmsdqECVKRNREEEIEQLNEVIEKlQQELANIGQKTLVDAHSLPEEADSLKHQldmviAEKLALEQQVETTNEEMTFTK 2368
Cdd:PTZ00121  1629 -----EEEKKKVEQLKKKEAEEKKK-AEELKKAEEENKIKAAEEAKKAEEDKKK-----AEEAKKAEEDEKKAAEALKKE 1697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2369 nilKETNFKMNQLTQELFSLKRERESMEKIQSIPGKSVNMAIDDMSKDKPELEVVLTEDALKsleNQTYLKSFEENGKGS 2448
Cdd:PTZ00121  1698 ---AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK---KKIAHLKKEEEKKAE 1771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2449 IINLETRLLQLESTVRAKDLELTQCYKQIKDMQEQGQSEIEVLQKKILNLQKILEEKVAA----ALVSQIQLEAVQEYAK 2524
Cdd:PTZ00121  1772 EIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAikevADSKNMQLEEADAFEK 1851

                          730
                   ....*....|....*.
gi 1622925520 2525 FCQDNQTISSEPERTN 2540
Cdd:PTZ00121  1852 HKFNKNNENGEDGNKE 1867
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 301-586 1.13e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  301 LQEKIKVYEMEQDKKVENSNKEEI-QEKETIIEELNT--KIIEEEKKTLELKDKLTAadkLLGELQEQVVQKNQEIKNMK 377
Cdd:pfam17380  278 VQHQKAVSERQQQEKFEKMEQERLrQEKEEKAREVERrrKLEEAEKARQAEMDRQAA---IYAEQERMAMERERELERIR 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  378 LElTNSKQKERQSSEEIKQLMGTVEELQK----RNHKDSQFETDI-----VQRMEQETQRK-------LEQLRAELDEMY 441
Cdd:pfam17380  355 QE-ERKRELERIRQEEIAMEISRMRELERlqmeRQQKNERVRQELeaarkVKILEEERQRKiqqqkveMEQIRAEQEEAR 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  442 GQQIVQMK------------QELIRQH----VSQMEELKTRHKGEMENALRSYPNItvNEDQIKLMNVAINELNIKLQDT 505
Cdd:pfam17380  434 QREVRRLEeeraremervrlEEQERQQqverLRQQEEERKRKKLELEKEKRDRKRA--EEQRRKILEKELEERKQAMIEE 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  506 NSQKEKLKEELGvilEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVE---DLKAEIVSASESR 582
Cdd:pfam17380  512 ERKRKLLEKEME---ERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMErerEMMRQIVESEKAR 588


                   ....
gi 1622925520  583 KELE 586
Cdd:pfam17380  589 AEYE 592
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
3063-3398 1.15e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.05  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3063 LKREQENEKSSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQE--QLSSEKMVVAELRSELAQTKLELETTL------ 3134
Cdd:PRK03918   243 LEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkEKAEEYIKLSEFYEEYLDELREIEKRLsrleee 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3135 -KAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSEERDKEELEDLKFSLESQKQRNLQ 3213
Cdd:PRK03918   323 iNGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEE 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3214 LNLLLEQQKQLLDESQQKIESQRM-------------LYDAQLSEEHGRNLELQVLLESEKVRiREMSSTLDRERELHAQ 3280
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKaieelkkakgkcpVCGRELTEEHRKELLEEYTAELKRIE-KELKEIEEKERKLRKE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3281 LQSNDGTGQSRPSLPSEDLLKELQKQLEEKHSRIV--ELLNETEKY-----KLDSLQTRQQMEKDRQVHRKTLQTEQEan 3353
Cdd:PRK03918   482 LRELEKVLKKESELIKLKELAEQLKELEEKLKKYNleELEKKAEEYeklkeKLIKLKGEIKSLKKELEKLEELKKKLA-- 559

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1622925520 3354 tEGQKKMHELQSKVEDLQRQLEEKR-QQVYKLDLEGQRLQGIMQEF 3398
Cdd:PRK03918   560 -ELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEY 604
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
3241-3380 1.23e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3241 AQLSEEHGRNLELQVLLESEKVRIREmsstldRERELHAQLQSNDGtgqsrpslpseDLLKELQKQLEEKHSRIVELLNE 3320
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALRE------ELDELEAQIRGNGG-----------DRLEQLEREIERLERELEERERR 360

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520 3321 TEKY-------KLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQ 3380
Cdd:COG4913    361 RARLeallaalGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 614-788 1.27e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  614 MAESQEA--ELERLRTQLlFSHEEELSKLKEDLEiEHQINIEKLKDNLgIHYKQQIDGLQNEMSqKIETMQFEKDNLITK 691
Cdd:COG1579      2 MPEDLRAllDLQELDSEL-DRLEHRLKELPAELA-ELEDELAALEARL-EAAKTELEDLEKEIK-RLELEIEEVEARIKK 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  692 QNQLILEISKLKDLQQslvnskseeMTLQINELQKEIEILRQEEKE----KGTLEQEVQELQLKIELLEKQMKEKENDLQ 767
Cdd:COG1579     78 YEEQLGNVRNNKEYEA---------LQKEIESLKRRISDLEDEILElmerIEELEEELAELEAELAELEAELEEKKAELD 148

                          170       180
                   ....*....|....*....|.
gi 1622925520  768 EKFTQLEAENSILKDEKKALE 788
Cdd:COG1579    149 EELAELEAELEELEAEREELA 169
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1805-2368 1.32e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.71  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1805 LQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEateslkCQEDLRERLHEESRAREQLAVELSKAEGVIDGYA- 1883
Cdd:pfam05483  188 LNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQH------LEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTf 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1884 --DEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKL 1961
Cdd:pfam05483  262 llEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1962 EVQCQAEKVRDDLQKQVKALE---------IDVEEQVSRFIELE-QEKNAELMDLRQQNQALEKQLEKMRKFL--DEQAI 2029
Cdd:pfam05483  342 KAKAAHSFVVTEFEATTCSLEellrteqqrLEKNEDQLKIITMElQKKSSELEEMTKFKNNKEVELEELKKILaeDEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2030 DREHERDVFQQEIQKLEQQLKV---------------VPRFQPISEHQTREVEQLTNHL--------------------- 2073
Cdd:pfam05483  422 DEKKQFEKIAEELKGKEQELIFllqarekeihdleiqLTAIKTSEEHYLKEVEDLKTELekeklknieltahcdklllen 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2074 KEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEAKPEL-SLEVQLQAERDA 2152
Cdd:pfam05483  502 KELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLdKSEENARSIEYE 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2153 IDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELeqenKLFKDDMEKLGLAIKESDAvstqdqh 2232
Cdd:pfam05483  582 VLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQL----NAYEIKVNKLELELASAKQ------- 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2233 vlfgKFAQIIQ--EKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNE- 2309
Cdd:pfam05483  651 ----KFEEIIDnyQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSe 726

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 2310 --VIEKLQQELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTK 2368
Cdd:pfam05483  727 lgLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1810-2585 1.37e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1810 EKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEDLRE----RLHEESRAREQLAVELSKAEGVIDGYADE 1885
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEkreyEGYELLKEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1886 KTLFERQIQEKTDIIDRLEQELlcasnrLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLlQETEKLMKEKLEVQC 1965
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLL------EELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI-AEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1966 QAEKVRDDLQKQVKALEIDVEEQVSRFIELE---QEKNAELMDLRQQNQALEKQLEKMRkfldEQAIDREHERDVFQQEI 2042
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTeeyAELKEELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2043 QKLEQQLKvvpRFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTF 2122
Cdd:TIGR02169  402 NELKRELD---RLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2123 QKVEDR-----KQFGAVEAKPELSLEVQL--QAERDAIDRKEKEITNLEEQLEQFREE------------LEN---KNEE 2180
Cdd:TIGR02169  479 DRVEKElsklqRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrLNNvvvEDDA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2181 VQQLHMQLEIQKKESTTRLQELeqeNKLfkDDMEKLGLAIKESDAVSTQDQHVLFGK-----FAQIIQEKEVEIDQlnEQ 2255
Cdd:TIGR02169  559 VAKEAIELLKRRKAGRATFLPL---NKM--RDERRDLSILSEDGVIGFAVDLVEFDPkyepaFKYVFGDTLVVEDI--EA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2256 IMKLQQQLKITTDNKVIEEKNELIrdleTQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTlvdaHSLPEE 2335
Cdd:TIGR02169  632 ARRLMGKYRMVTLEGELFEKSGAM----TGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL----RRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2336 ADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKREresmekiqsipgksvnmaIDDMSK 2415
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE------------------LKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2416 DKPELEVVLT--EDALKSLENQTYLKSFEENGKGS------IINLETRLLQLESTVRAKDLELTQCYKQIKDMQEQG--- 2484
Cdd:TIGR02169  766 RIEELEEDLHklEEALNDLEARLSHSRIPEIQAELskleeeVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRidl 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2485 -------QSEIEVLQKKILNLQKILEEKVAAALvsqiQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDESgSNIS 2557
Cdd:TIGR02169  846 keqiksiEKEIENLNGKKEELEEELEELEAALR----DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR-KRLS 920

                          810       820
                   ....*....|....*....|....*...
gi 1622925520 2558 ALTLRISELESQLVEMHTSLILGKEQVE 2585
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPE 948
PRK11281 PRK11281
mechanosensitive channel MscK;
318-772 1.44e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.90  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  318 NSNKEEIQEKETIIEELNTkiieeekkTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQL 397
Cdd:PRK11281    49 NKQKLLEAEDKLVQQDLEQ--------TLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLST 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  398 MgTVEELQkrnhkdsqfetdivQRMEQeTQRKLEQLRAELDEMYGQQIVQMkqelirqhvSQMEelktrhkgemenalRS 477
Cdd:PRK11281   121 L-SLRQLE--------------SRLAQ-TLDQLQNAQNDLAEYNSQLVSLQ---------TQPE--------------RA 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  478 YPNITVNEDQIKLMNVAINELNI-KLQDTNSQKEKLKEELgVILEEKCALQR-------QLEDLFE-ELSFSREQIQRAR 548
Cdd:PRK11281   162 QAALYANSQRLQQIRNLLKGGKVgGKALRPSQRVLLQAEQ-ALLNAQNDLQRkslegntQLQDLLQkQRDYLTARIQRLE 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  549 QTIAEQESKLNEAQKSLS--TVE-----DLKAEIVSASESRKELELKHeaEVTNYKI----KLEMLEKE----KNaVLDR 613
Cdd:PRK11281   241 HQLQLLQEAINSKRLTLSekTVQeaqsqDEAARIQANPLVAQELEINL--QLSQRLLkateKLNTLTQQnlrvKN-WLDR 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  614 MAESQEAelerlrtqllfsheeelsklkedleIEHQINIekLKDNL---GIHYKQQI----DGLQNEMSQKIETM---QF 683
Cdd:PRK11281   318 LTQSERN-------------------------IKEQISV--LKGSLllsRILYQQQQalpsADLIEGLADRIADLrleQF 370

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  684 EkdnlITKQNQlilEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEekekgTLEQEVQEL--QL----KIELLEK 757
Cdd:PRK11281   371 E----INQQRD---ALFQPDAYIDKLEAGHKSEVTDEVRDALLQLLDERRE-----LLDQLNKQLnnQLnlaiNLQLNQQ 438

                          490
                   ....*....|....*
gi 1622925520  758 QMKEKENDLQEKFTQ 772
Cdd:PRK11281   439 QLLSVSDSLQSTLTQ 453
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
651-850 1.74e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  651 NIEKLKdnlgiHYKQQIDGLQNEMSQ---KIETMQFEKDNLITKQNQLileiSKLKDLQQSLVNSKSEEMTLQinELQKE 727
Cdd:COG4913    608 NRAKLA-----ALEAELAELEEELAEaeeRLEALEAELDALQERREAL----QRLAEYSWDEIDVASAEREIA--ELEAE 676

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  728 IEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEkendLQEKFTQLEAENSILKDEKKALEDMLKIHTPDNQEERLIFID 807
Cdd:COG4913    677 LERLDASSDDLAALEEQLEELEAELEELEEELDE----LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1622925520  808 SIKSKSKDSVWEKEI-EILTEENEDLKQQCIQLNEEIEKQRNTF 850
Cdd:COG4913    753 ERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAF 796
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2131-2361 1.80e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2131 FGAVEAKPELSLEVQLQAERDAIDRKEKEI-------TNLEEQLEQFREELENKNEEVQQLHMQLEIQKKE---STTRLQ 2200
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELaalkkeeKALLKQLAALERRIAALARRIRALEQELAALEAElaeLEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2201 ELEQENKLFKDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVeIDQLNEQIMKLQQQLKITTDNkvIEEKNELIR 2280
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAE--LAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2281 DLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKtlvdAHSLPEEADSLKHQLDMVIAEKLALEQQVETT 2360
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAE----LAELQQEAEELEALIARLEAEAAAAAERTPAA 246


                   .
gi 1622925520 2361 N 2361
Cdd:COG4942    247 G 247
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1862-2515 1.94e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1862 SRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELL----SRQKEA 1937
Cdd:TIGR00618  183 LMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQeeqlKKQQLL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1938 MKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKvrddLQKQVKALEiDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQ- 2016
Cdd:TIGR00618  263 KQLRARIEELRAQEAVLEETQERINRARKAAP----LAAHIKAVT-QIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQq 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2017 --LEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPIS--EHQTREVEQLTNHLKEKTDKCSEL---LLSKEQ 2089
Cdd:TIGR00618  338 ssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHtlQQQKTTLTQKLQSLCKELDILQREqatIDTRTS 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2090 LQRDIQE---RNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfgaVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQ 2166
Cdd:TIGR00618  418 AFRDLQGqlaHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHL---QESAQSLKEREQQLQTKEQIHLQETRKKAVVLA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2167 LEQFREELE---NKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL---GLAIKE---SDAVSTQDQHVLFGK 2237
Cdd:TIGR00618  495 RLLELQEEPcplCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVyhqLTSERKqraSLKEQMQEIQQSFSI 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2238 FAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQE 2317
Cdd:TIGR00618  575 LTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLT 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2318 LANIGQKtlvdahslpEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKRERESMEK 2397
Cdd:TIGR00618  655 LTQERVR---------EHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2398 IQSIPGKSVNMAIDDMSKDKPELEvVLTEDALKSLENQTYLKSFEENgkgSIINLETRLLQLESTVRAKDLELTQCYKQI 2477
Cdd:TIGR00618  726 ASSSLGSDLAAREDALNQSLKELM-HQARTVLKARTEAHFNNNEEVT---AALQTGAELSHLAAEIQFFNRLREEDTHLL 801

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1622925520 2478 KDMQEQGQSEIEVlQKKILNLQKILEEKVAAALVSQIQ 2515
Cdd:TIGR00618  802 KTLEAEIGQEIPS-DEDILNLQCETLVQEEEQFLSRLE 838
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 185-464 1.94e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 44.25  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  185 YGTEGLQQLQEFEAAIKQrDGIITQLTAnlQQARREKDETMrefleLTEQSQKLQIQFQQLQASeTLRNSTHSSTAADLL 264
Cdd:pfam05667  211 RNAAELAAAQEWEEEWNS-QGLASRLTP--EEYRKRKRTKL-----LKRIAEQLRSAALAGTEA-TSGASRSAQDLAELL 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  265 QAKQQIRTHQQQLEEQDHLLedyQKKKEDFTmQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKK 344
Cdd:pfam05667  282 SSFSGSSTTDTGLTKGSRFT---HTEKLQFT-NEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  345 TLELKDKLTAADKLLGELQEQVVQKNQEIKNMK--LEL-----TNSKQKER---QSSEEIKQLMGTVEELQK------RN 408
Cdd:pfam05667  358 IKKLESSIKQVEEELEELKEQNEELEKQYKVKKktLDLlpdaeENIAKLQAlvdASAQRLVELAGQWEKHRVplieeyRA 437

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622925520  409 HKDSQFETdivqrmEQETQRKLEQ---LRAELDEMygQQIVQMKQELIRQHVSQMEELK 464
Cdd:pfam05667  438 LKEAKSNK------EDESQRKLEEikeLREKIKEV--AEEAKQKEELYKQLVAEYERLP 488
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
148-577 1.96e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 1.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  148 QGAQYSLTHLEMMESELAGKQHEIEELNRELEEMRVTYGT-EGLQQLQEFEAAIKQRDGIIT--QLTANLQQARREKDET 224
Cdd:PRK03918   324 NGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELERLKKRLTGLTpeKLEKELEELEKAKEEI 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  225 MREFLELTEQSQKLQIQFQQLQ-ASETL-----------RNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKE 292
Cdd:PRK03918   404 EEEISKITARIGELKKEIKELKkAIEELkkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR 483

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  293 DFTMQISFLQEKIKVYEM-EQDKKVENS----NKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEqVV 367
Cdd:PRK03918   484 ELEKVLKKESELIKLKELaEQLKELEEKlkkyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAE-LE 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  368 QKNQEIKNMKLELtnSKQKERQSSEEIKQLMGTVEELQKRNH-----KDSQFETDIVQRMEQETQRKLEQLRAELDEMYG 442
Cdd:PRK03918   563 KKLDELEEELAEL--LKELEELGFESVEELEERLKELEPFYNeylelKDAEKELEREEKELKKLEEELDKAFEELAETEK 640

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  443 QqivqmkqelIRQHVSQMEELKTRH-KGEMENALRSYpniTVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILE 521
Cdd:PRK03918   641 R---------LEELRKELEELEKKYsEEEYEELREEY---LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622925520  522 EKCALqrqledlfEELSFSREQIQRARQTIAEQESKLNEAqkSLSTVEDLKAEIVS 577
Cdd:PRK03918   709 AKKEL--------EKLEKALERVEELREKVKKYKALLKER--ALSKVGEIASEIFE 754
PTZ00121 PTZ00121
MAEBL; Provisional
 1933-2414 1.99e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1933 RQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIEL----EQEKNAELMDLRQ 2008
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2009 QNQALE-KQLEKMRKFLD----EQAIDREHERDVFQQEIQKLEQQlkvvprfqpiseHQTREVEQLTNHLKEKTDKCSEL 2083
Cdd:PTZ00121  1545 KKKADElKKAEELKKAEEkkkaEEAKKAEEDKNMALRKAEEAKKA------------EEARIEEVMKLYEEEKKMKAEEA 1612

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2084 LLSKEQlqrdiQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfgaveAKPELSLEVQLQAERDAIDRKEKEITNL 2163
Cdd:PTZ00121  1613 KKAEEA-----KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKK 1682

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2164 EEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKES--DAVSTQDQHVLFGKFAQI 2241
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDkkKAEEAKKDEEEKKKIAHL 1762

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2242 IQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQE----CVKRNREEEIEQLNEVI--EKLQ 2315
Cdd:PTZ00121  1763 KKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKegnlVINDSKEMEDSAIKEVAdsKNMQ 1842

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2316 QELANIGQKTLVDAHSLPEEADSLKHQLDMVIAEKLALEQQVETTNEEMTFTKNILKE----TNFKMN-------QLTQE 2384
Cdd:PTZ00121  1843 LEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEReipnNNMAGKnndiiddKLDKD 1922

                          490       500       510
                   ....*....|....*....|....*....|
gi 1622925520 2385 LFSLKRERESMEKIQSIPGKsvNMAIDDMS 2414
Cdd:PTZ00121  1923 EYIKRDAEETREEIIKISKK--DMCINDFS 1950
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
701-1005 2.08e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  701 KLKDLQQSLVNSKSE--EMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENS 778
Cdd:PRK03918   194 LIKEKEKELEEVLREinEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKK 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  779 ILKDEKKALEDMLKIHTPDNQEERLI-FIDSIKSKSKDSvwEKEIEILTEENEDLKQQCIQL---NEEIEKQRNTFSFAE 854
Cdd:PRK03918   274 EIEELEEKVKELKELKEKAEEYIKLSeFYEEYLDELREI--EKRLSRLEEEINGIEERIKELeekEERLEELKKKLKELE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  855 KNFEVnYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHlqrinpttvKTKSSVFDEDKTFVAETLEMgEVV 934
Cdd:PRK03918   352 KRLEE-LEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELE---------KAKEEIEEEISKITARIGEL-KKE 420

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  935 EKDTTELMEKLEVTKRE----KLELSQRlaDLSEQLKQKHGEISFLNEEVKSLKQEKEQVLLRCRELEIIINHNR 1005
Cdd:PRK03918   421 IKELKKAIEELKKAKGKcpvcGRELTEE--HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES 493
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
3068-3401 2.12e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 2.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3068 ENEKSSQEL--LEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQTKLELETTLKaqhkHLKELE 3145
Cdd:PRK02224   245 EHEERREELetLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEA----RREELE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3146 AFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLL 3225
Cdd:PRK02224   321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERF 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3226 D---ESQQKIESQRMLYDAQLSEEHGRNLELQVLLESEKVRIREMSSTLDR----------ERELHAqlqsnDGTGQSRP 3292
Cdd:PRK02224   401 GdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHV-----ETIEEDRE 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3293 SLPS-EDLLKELQKQLEEKHSRI--VELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEantegqkKMHELQSKVED 3369
Cdd:PRK02224   476 RVEElEAELEDLEEEVEEVEERLerAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRE-------RAEELRERAAE 548

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1622925520 3370 LQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQ 3401
Cdd:PRK02224   549 LEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 2088-2317 2.13e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.47  E-value: 2.13e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  2088 EQLQRDIQERNEEIEKLEFRVRELEQALLV---SADTFQKVEDRKQFGAVEAKPELslevqlQAERDAIDRKEKEITNLE 2164
Cdd:smart00787   73 KELKKYISEGRDLFKEIEEETLINNPPLFKeyfSASPDVKLLMDKQFQLVKTFARL------EAKKMWYEWRMKLLEGLK 146

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  2165 EQLEQFREELENKNEEVQQ-------LHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKEsdAVSTQDQHvlfgk 2237
Cdd:smart00787  147 EGLDENLEGLKEDYKLLMKelellnsIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKE--KLKKLLQE----- 219

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  2238 faqiIQEKEVEIDQLNEQIMKLQQqlkittdnkVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQE 2317
Cdd:smart00787  220 ----IMIKVKKLEELEEELQELES---------KIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
PTZ00121 PTZ00121
MAEBL; Provisional
 3029-3384 2.16e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3029 EYQAAMEYLQKADRRSLLSEIQALHAQMNGRKITLKREQENEKSSQElleynIQQKQSQMLEMQVELSSMKDRATELQEQ 3108
Cdd:PTZ00121  1300 EKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAE-----AAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3109 LSSEKMVVAELRSELAQTKLELETTLKAQHKHLKELEAFRL------EVKDKTDEVHLLNDT--LASEQKKSREL-QWAL 3179
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAakkkadEAKKKAEEKKKADEAkkKAEEAKKADEAkKKAE 1454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3180 EKEKAKLGHSEERDKEELEDLKFSLEsQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLES 3259
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3260 EKVRIREMSSTLDRERELHaqlqsndgtgQSRPSLPSEDLLKELQKQLEEKHS----RIVELLNETEKYKLDSLQTRQQM 3335
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELK----------KAEELKKAEEKKKAEEAKKAEEDKnmalRKAEEAKKAEEARIEEVMKLYEE 1603

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1622925520 3336 EKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYKL 3384
Cdd:PTZ00121  1604 EKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652
46 PHA02562
endonuclease subunit; Provisional
 266-460 2.17e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 2.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  266 AKQQIRTHQQQLEEQDHL----LEDYQKK-------KEDFTMQISFLQEKIKVYEMEQDK-----------------KVE 317
Cdd:PHA02562   193 IQQQIKTYNKNIEEQRKKngenIARKQNKydelveeAKTIKAEIEELTDELLNLVMDIEDpsaalnklntaaakiksKIE 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  318 NSNKEE-IQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQvVQKNQEIKNMKLELTNSKQKERQSSEEIKQ 396
Cdd:PHA02562   273 QFQKVIkMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTA-IDELEEIMDEFNEQSKKLLELKNKISTNKQ 351

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  397 LMGTVEELQKRNHKD-SQFETDIVQRMEQetqrkLEQLRAELDEMYGQQIVQMKQELIRQHVSQM 460
Cdd:PHA02562   352 SLITLVDKAKKVKAAiEELQAEFVDNAEE-----LAKLQDELDKIVKTKSELVKEKYHRGIVTDL 411
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3100-3380 2.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3100 DRATELQEQLSsekmvvaELRSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQwal 3179
Cdd:COG4942     20 DAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE--- 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3180 ekekaklghseerdkEELEDLKFSLESQKQrnlqlnllleqqkqlldesqqkiESQRMLYDAQLSeehGRNLELQVLLES 3259
Cdd:COG4942     90 ---------------KEIAELRAELEAQKE-----------------------ELAELLRALYRL---GRQPPLALLLSP 128

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3260 EK----VRIREMSSTLDRERELHAQLQSNDgtgqsrpslpsEDLLKELQKQLEEKHSRIVELLNETEkykldslQTRQQM 3335
Cdd:COG4942    129 EDfldaVRRLQYLKYLAPARREQAEELRAD-----------LAELAALRAELEAERAELEALLAELE-------EERAAL 190

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1622925520 3336 EKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQ 3380
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
46 PHA02562
endonuclease subunit; Provisional
 2094-2324 2.34e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2094 IQERNEEIEKLEFRVRELEQALlvsaDTFQKVEDRkqfgaveakpelslevQLQAERDAIDRKEKEITNLEEQLEQFREE 2173
Cdd:PHA02562   176 IRELNQQIQTLDMKIDHIQQQI----KTYNKNIEE----------------QRKKNGENIARKQNKYDELVEEAKTIKAE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2174 LENKNEEVQQLHMQLEiqkkESTTRLQELEQENKLFKDDMEKLGLAIK-----------------ESDAVS--TQDQHVL 2234
Cdd:PHA02562   236 IEELTDELLNLVMDIE----DPSAALNKLNTAAAKIKSKIEQFQKVIKmyekggvcptctqqiseGPDRITkiKDKLKEL 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2235 FGKFAQI---IQEKEVEIDQLNEQIMKLQQ-QLKITTDNKVIEEKNELIRDLETQIECLMSDqecvKRNREEEIEQLNEV 2310
Cdd:PHA02562   312 QHSLEKLdtaIDELEEIMDEFNEQSKKLLElKNKISTNKQSLITLVDKAKKVKAAIEELQAE----FVDNAEELAKLQDE 387

                          250
                   ....*....|....
gi 1622925520 2311 IEKLQQELANIGQK 2324
Cdd:PHA02562   388 LDKIVKTKSELVKE 401
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 2154-2324 2.35e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 43.26  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2154 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQE--------------LEQENKLFKDDMEKLGLA 2219
Cdd:pfam15905  148 DGTQKKMSSLSMELMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHskgkvaqleeklvsTEKEKIEEKSETEKLLEY 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2220 IKESDAVSTQDQhvlfgKFAQIIQEKEVEIDQLNEQIMKLQQQL--KITTDNKVIEEKNELIRDLETQIECLMSDQECVK 2297
Cdd:pfam15905  228 ITELSCVSEQVE-----KYKLDIAQLEELLKEKNDEIESLKQSLeeKEQELSKQIKDLNEKCKLLESEKEELLREYEEKE 302

                          170       180
                   ....*....|....*....|....*..
gi 1622925520 2298 RNREEEIEQLNEVIEKLQQELANIGQK 2324
Cdd:pfam15905  303 QTLNAELEELKEKLTLEEQEHQKLQQK 329
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 323-568 3.11e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  323 EIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGtve 402
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR--- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  403 ELQKRNHKDSQFE--------TDIVQRMEqetqrkleqlraeldemYGQQIVQMKQELIRQHVSQMEELKTRHKGemena 474
Cdd:COG3883     94 ALYRSGGSVSYLDvllgsesfSDFLDRLS-----------------ALSKIADADADLLEELKADKAELEAKKAE----- 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  475 lrsypnitvNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQ 554
Cdd:COG3883    152 ---------LEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222

                          250
                   ....*....|....
gi 1622925520  555 ESKLNEAQKSLSTV 568
Cdd:COG3883    223 AAAAAAAAAAAAAA 236
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 209-782 3.14e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 3.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  209 QLTANLQQARREKDETMREFLELTEQSQKLQiqfqqlQASETLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDhlLEDYQ 288
Cdd:TIGR00606  574 QLEDWLHSKSKEINQTRDRLAKLNKELASLE------QNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESD--LERLK 645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  289 KKKEDFTMQISFLQEKIKVYE--MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQ- 365
Cdd:TIGR00606  646 EEIEKSSKQRAMLAGATAVYSqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRr 725

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  366 ------VVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQK---------RNHKDSQFETDIVQRMEQET---Q 427
Cdd:TIGR00606  726 demlglAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETllgtimpeeESAKVCLTDVTIMERFQMELkdvE 805

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  428 RKLEQLRAELDEMYG-------QQIVQMKQELIRQHVSQMEELKTrhkgemenalrsypnitVNEDQiklmnvaiNELNI 500
Cdd:TIGR00606  806 RKIAQQAAKLQGSDLdrtvqqvNQEKQEKQHELDTVVSKIELNRK-----------------LIQDQ--------QEQIQ 860

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  501 KLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSlstvedlKAEIVSASE 580
Cdd:TIGR00606  861 HLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQE-------KEELISSKE 933

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  581 SRKElelKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERlrtqllfsHEEELSKLKEDLEiEHQINIEKLKDNLG 660
Cdd:TIGR00606  934 TSNK---KAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQ--------KETELNTVNAQLE-ECEKHQEKINEDMR 1001

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  661 IhYKQQIDglqnemSQKIETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 739
Cdd:TIGR00606 1002 L-MRQDID------TQKIQERWLQDNLTLRKRENELKEVEEeLKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLAL 1074

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622925520  740 TLEQEVQE--LQLKIELLEKQMKEKENDLQEKFTQLEAENSILKD 782
Cdd:TIGR00606 1075 GRQKGYEKeiKHFKKELREPQFRDAEEKYREMMIVMRTTELVNKD 1119
46 PHA02562
endonuclease subunit; Provisional
 531-792 3.15e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.46  E-value: 3.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  531 EDLFEELSFS------REQIQRARQTIAEQESKLNEAQKSLSTVEDLKaeivsasesrKELELKHEAEVTNYKIKLEMLE 604
Cdd:PHA02562   157 EDLLDISVLSemdklnKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNI----------EEQRKKNGENIARKQNKYDELV 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  605 KEknavldrmAESQEAELERLRTQLLfsheeelsklkedleiEHQINIEKLKDNLGiHYKQQIDGLQNEMSQ--KIETMQ 682
Cdd:PHA02562   227 EE--------AKTIKAEIEELTDELL----------------NLVMDIEDPSAALN-KLNTAAAKIKSKIEQfqKVIKMY 281

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  683 FEKDNLITKQNQLILEISKLKDLQQSLVnskseEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMK-- 760
Cdd:PHA02562   282 EKGGVCPTCTQQISEGPDRITKIKDKLK-----ELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLItl 356

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1622925520  761 -EKENDLQEKFTQLEAENSILKDEKKALEDMLK 792
Cdd:PHA02562   357 vDKAKKVKAAIEELQAEFVDNAEELAKLQDELD 389
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1931-2585 3.27e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1931 LSRQKEAMKAEAGPVEQQLLQEtEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNA--------- 2001
Cdd:pfam05483   83 LYKEAEKIKKWKVSIEAELKQK-ENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNAtrhlcnllk 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2002 ---------------ELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQ-------QEIQKLEQQLK--------V 2051
Cdd:pfam05483  162 etcarsaektkkyeyEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHfklkedhEKIQHLEEEYKkeindkekQ 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2052 VPRFQPISEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQF 2131
Cdd:pfam05483  242 VSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQI 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2132 gAVEAKPELSLEVQLQAERD---------AIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMqlEIQKKESttrlqEL 2202
Cdd:pfam05483  322 -ATKTICQLTEEKEAQMEELnkakaahsfVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITM--ELQKKSS-----EL 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2203 EQENKLfkddmeklglaikesdavsTQDQHVLFGKFAQIIQEKEVEIDQlNEQIMKLQQQLKITTDNKV--IEEKNELIR 2280
Cdd:pfam05483  394 EEMTKF-------------------KNNKEVELEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIflLQAREKEIH 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2281 DLETQIECLMSDQECVKRNREEEIEQLNEviEKLQQ-ELANIGQKTLVDAHSLPEEADslkhqlDMViaekLALEQQVET 2359
Cdd:pfam05483  454 DLEIQLTAIKTSEEHYLKEVEDLKTELEK--EKLKNiELTAHCDKLLLENKELTQEAS------DMT----LELKKHQED 521

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2360 TNEEMTFTKNILKEtnfkMNQLTQELFSLKRERESMEKIQSIPGKSVNMAIDDMSKD--KPELEVVLTEDALKSLENQ-T 2436
Cdd:pfam05483  522 IINCKKQEERMLKQ----IENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENarSIEYEVLKKEKQMKILENKcN 597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2437 YLKSFEENGKGSIINL--ETRLLQLESTVRAK------------DLELTQCYKQIKDMQEQGQSEIEVlqkKILNLQKIL 2502
Cdd:pfam05483  598 NLKKQIENKNKNIEELhqENKALKKKGSAENKqlnayeikvnklELELASAKQKFEEIIDNYQKEIED---KKISEEKLL 674

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2503 EEKVAAALVSQIQLEAVQEYAKFCQ-------------DNQTISSEPERTNIQNLNQLREDESGSNISALTLRISELESQ 2569
Cdd:pfam05483  675 EEVEKAKAIADEAVKLQKEIDKRCQhkiaemvalmekhKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAE 754

                          730
                   ....*....|....*.
gi 1622925520 2570 LVEMHTSLILGKEQVE 2585
Cdd:pfam05483  755 LLSLKKQLEIEKEEKE 770
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
419-998 3.31e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.49  E-value: 3.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  419 VQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELiRQHVSQMEELKTRHKGEMENALRSYPN----ITVNE---DQIKLM 491
Cdd:PRK02224   178 VERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGL-ESELAELDEEIERYEEQREQARETRDEadevLEEHEerrEELETL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  492 NVAINELNIKLQDTNSQKEKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTV--- 568
Cdd:PRK02224   257 EAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrva 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  569 -EDLKAEIVSASESRKELELKHEAevtnykiklemlEKEKNAVLDRMAESQEAELERLRTQL--LFSHEEELSKLKEDLE 645
Cdd:PRK02224   337 aQAHNEEAESLREDADDLEERAEE------------LREEAAELESELEEAREAVEDRREEIeeLEEEIEELRERFGDAP 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  646 IEHQiNIEKLKDNLgihyKQQIDGLQNEMSQKIETMQFEKDNLitKQNQLILEISKLKDLQQSLVNSkseemtlqinelq 725
Cdd:PRK02224   405 VDLG-NAEDFLEEL----REERDELREREAELEATLRTARERV--EEAEALLEAGKCPECGQPVEGS------------- 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  726 KEIEILRQEEKEKGTLEQEVQELQLKIELLEKQMKEKEnDLQEkftqLEAENSILKDEKKALEDMLKIHTPDNQEERLif 805
Cdd:PRK02224   465 PHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVE----AEDRIERLEERREDLEELIAERRETIEEKRE-- 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  806 idsiKSKSKDsvweKEIEILTEENEDLKQQCIQLNEEIEKQRNTFsfaeKNFEVNYQELQEEYACLLKVKDDLEDSKNkq 885
Cdd:PRK02224   538 ----RAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREEV----AELNSKLAELKERIESLERIRTLLAAIAD-- 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  886 eleYKSKLKALNEEL-HLQRINpttvktkssvfDEDKTFVAETLEM-----GEVVEKDTTELMEKLEVTKREKLELSQRL 959
Cdd:PRK02224   604 ---AEDEIERLREKReALAELN-----------DERRERLAEKRERkreleAEFDEARIEEAREDKERAEEYLEQVEEKL 669

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622925520  960 ADLSEQLKQKHGEISFLN---EEVKSLKQEKEQVLLRCRELE 998
Cdd:PRK02224   670 DELREERDDLQAEIGAVEnelEELEELRERREALENRVEALE 711
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1806-2205 3.57e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 3.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1806 QAAVEKLLEAISETSSQLEHAKVTQTELMRESfrqkqeatESLKCQEDLRERLHEESRAREQLAVELSKAEGVIDGYADE 1885
Cdd:COG4717     87 EEEYAELQEELEELEEELEELEAELEELREEL--------EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1886 KTLfERQIQEKTDIIDRLEQEL-LCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQL--LQETEKLMKEKLE 1962
Cdd:COG4717    159 REL-EEELEELEAELAELQEELeELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELeeLEEELEQLENELE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1963 VQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQ-E 2041
Cdd:COG4717    238 AAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEElE 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2042 IQKLEQQLKVVPRFQPISEHQTREVEQLTNHLKEKTDKCSELllskeQLQRDIQERNEEIEKL--EFRVRELEQALLVSA 2119
Cdd:COG4717    318 EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL-----EEELQLEELEQEIAALlaEAGVEDEEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2120 DTFQKVEDRKQFGAVEAK-PELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLhmQLEIQKKESTTR 2198
Cdd:COG4717    393 QAEEYQELKEELEELEEQlEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAEL--EAELEQLEEDGE 470


                   ....*..
gi 1622925520 2199 LQELEQE 2205
Cdd:COG4717    471 LAELLQE 477
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
3021-3201 3.62e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3021 QRIQEQGVEYQAAMEYLQKADRrsllsEIQALHAQMNGRKITLKREQenekssQELLEYNIQQKQSQMLEMQVELSSMKD 3100
Cdd:COG4913    255 EPIRELAERYAAARERLAELEY-----LRAALRLWFAQRRLELLEAE------LEELRAELARLEAELERLEARLDALRE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3101 RATELQEQLSSEKMV-VAELRSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWAL 3179
Cdd:COG4913    324 ELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEAL 403

                          170       180
                   ....*....|....*....|..
gi 1622925520 3180 EKEKAKLGHSEERDKEELEDLK 3201
Cdd:COG4913    404 EEALAEAEAALRDLRRELRELE 425
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
 503-654 3.69e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 43.51  E-value: 3.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  503 QDTNSQKeKLKEELGVILEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDlkaEIVSASESR 582
Cdd:pfam05911  678 LKTEENK-RLKEEFEQLKSEKENLEVELASCTENLESTKSQLQESEQLIAELRSELASLKESNSLAET---QLKCMAESY 753

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622925520  583 KELELKH---EAEVTNYKIKLEMLEKEknaVLDRMAESQEAELERLRTQL-LFSHEEELSKLKEDLEIEHQINIEK 654
Cdd:pfam05911  754 EDLETRLtelEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQEqLERNEKKESSNCDADQEDKKLQQEK 826
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2062-2325 3.75e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2062 QTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVsadtfqkvedrkqfgaveakpels 2141
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA------------------------ 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2142 LEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKddmeklglAIK 2221
Cdd:COG4942     74 LEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLK--------YLA 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2222 ESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKitTDNKVIEEKNELIRDLETQIEclmSDQECVKRNRE 2301
Cdd:COG4942    146 PARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA--ALEALKAERQKLLARLEKELA---ELAAELAELQQ 220

                          250       260
                   ....*....|....*....|....
gi 1622925520 2302 EEiEQLNEVIEKLQQELANIGQKT 2325
Cdd:COG4942    221 EA-EELEALIARLEAEAAAAAERT 243
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 703-846 3.77e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 43.09  E-value: 3.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  703 KDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEkgTLEQEVQELQLKIELLEKQMKEKENDLQ---EKFTQLEAENSI 779
Cdd:pfam05667  304 EKLQFTNEAPAATSSPPTKVETEEELQQQREEELE--ELQEQLEDLESSIQELEKEIKKLESSIKqveEELEELKEQNEE 381

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520  780 LKDEKKALEDMLKI-HTPDNQEERL--IFIDSIKSKSKDSV-WEKEIEILTEENEDLKQQCIQLNEEIEKQ 846
Cdd:pfam05667  382 LEKQYKVKKKTLDLlPDAEENIAKLqaLVDASAQRLVELAGqWEKHRVPLIEEYRALKEAKSNKEDESQRK 452
PRK12704 PRK12704
phosphodiesterase; Provisional
 2134-2204 3.90e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 3.90e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622925520 2134 VEAKPELsLEVQLQAERDaIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQ 2204
Cdd:PRK12704    60 LEAKEEI-HKLRNEFEKE-LRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEK 128
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 3021-3356 3.96e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 3.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3021 QRIQEQGVEYQAAMEYLQKADRRSLLSEIQALHAQmngrKITLKREQENEKSSQELLEYNIQQKQSQMLEMQVELSSMKD 3100
Cdd:TIGR02169  204 RREREKAERYQALLKEKREYEGYELLKEKEALERQ----KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3101 RAtelqEQLSSEKMVvaELRSELAQTKLELETTLKAQHkhLKELEAFRLEVKDKTDEVHLlnDTLASEQKKSRELQWALE 3180
Cdd:TIGR02169  280 KI----KDLGEEEQL--RVKEKIGELEAEIASLERSIA--EKERELEDAEERLAKLEAEI--DKLLAEIEELEREIEEER 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3181 KEKAKLGHSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDaqlseehgrnlELQVLLESE 3260
Cdd:TIGR02169  350 KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD-----------RLQEELQRL 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3261 KVRIREMSSTLDRERELHAQLQSNDGTGQSRPSlPSEDLLKELQKQL---EEKHSRIVELLNETEK------YKLDSLQT 3331
Cdd:TIGR02169  419 SEELADLNAAIAGIEAKINELEEEKEDKALEIK-KQEWKLEQLAADLskyEQELYDLKEEYDRVEKelsklqRELAEAEA 497

                          330       340
                   ....*....|....*....|....*
gi 1622925520 3332 RQQMEKDRQVHRKTLQTEQEANTEG 3356
Cdd:TIGR02169  498 QARASEERVRGGRAVEEVLKASIQG 522
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1983-2286 4.04e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1983 IDVEEQVSRFIELEQEKnaelmdLRQQNQALEKQLEKMRKfLDEQAIDREHERDvfQQEIQKLEQQLKVVPRFQPIS--- 2059
Cdd:pfam17380  284 VSERQQQEKFEKMEQER------LRQEKEEKAREVERRRK-LEEAEKARQAEMD--RQAAIYAEQERMAMERERELErir 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2060 -EHQTREVEQL-TNHLKEKTDKCSELllskEQLQRDIQERNEEIEKlefrvrELEQA----LLVSADTFQKVEDRKQFGA 2133
Cdd:pfam17380  355 qEERKRELERIrQEEIAMEISRMREL----ERLQMERQQKNERVRQ------ELEAArkvkILEEERQRKIQQQKVEMEQ 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2134 VEAKPELSLEVQLQ---AERD-AIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLF 2209
Cdd:pfam17380  425 IRAEQEEARQREVRrleEERArEMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEER 504

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520 2210 KDDMEKLGLAIKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQLNEQIMKLQQQLKITTDNKVIEEKNELIRDLETQI 2286
Cdd:pfam17380  505 KQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQI 581
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 2039-2344 4.21e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 43.09  E-value: 4.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2039 QQEIQKLEQQLKVVPRFQPIsEHQTREVEQLTNHLKEKTDKCseLLLSKEQLQRDIQERNEEIEKL-EFRVRELEQALLV 2117
Cdd:pfam05667  219 AQEWEEEWNSQGLASRLTPE-EYRKRKRTKLLKRIAEQLRSA--ALAGTEATSGASRSAQDLAELLsSFSGSSTTDTGLT 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2118 SADTFQKVEDRkQFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHM---QLEIQKKE 2194
Cdd:pfam05667  296 KGSRFTHTEKL-QFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESsikQVEEELEE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2195 STTRLQELEQENKLFK----------DDMEKLGLAIKEsdavSTQDQHVLFGKF--------------AQIIQEKEVEID 2250
Cdd:pfam05667  375 LKEQNEELEKQYKVKKktldllpdaeENIAKLQALVDA----SAQRLVELAGQWekhrvplieeyralKEAKSNKEDESQ 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2251 QLNEQIMKLQQQLKittdnKVIEE---KNELIRDLETQIECLMSDQecvkrNREEEIEQLNEV---IEKLQQELanigQK 2324
Cdd:pfam05667  451 RKLEEIKELREKIK-----EVAEEakqKEELYKQLVAEYERLPKDV-----SRSAYTRRILEIvknIKKQKEEI----TK 516

                          330       340
                   ....*....|....*....|
gi 1622925520 2325 TLVDAHSLPEEADSLKHQLD 2344
Cdd:pfam05667  517 ILSDTKSLQKEINSLTGKLD 536
PRK11281 PRK11281
mechanosensitive channel MscK;
190-400 4.31e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 4.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  190 LQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQ--------------------KLQIQFQQLQA-- 247
Cdd:PRK11281    65 LEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDeetretlstlslrqlesrlaQTLDQLQNAQNdl 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  248 ---------------------------SETLRNSTHSSTAA---------DLLQAKQ-----QIRTHQQQLEEQDHLLED 286
Cdd:PRK11281   145 aeynsqlvslqtqperaqaalyansqrLQQIRNLLKGGKVGgkalrpsqrVLLQAEQallnaQNDLQRKSLEGNTQLQDL 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  287 YQKKKEDFTMQISFLQEKIKVY-EMEQDKKVENSNK-----EEIQEKETIIEelNTKIIEEEKKTLELKDKLTAADKLLG 360
Cdd:PRK11281   225 LQKQRDYLTARIQRLEHQLQLLqEAINSKRLTLSEKtvqeaQSQDEAARIQA--NPLVAQELEINLQLSQRLLKATEKLN 302

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1622925520  361 ELqeqvVQKNQEIKNMkleLTNSKQKERQSSEEIKQLMGT 400
Cdd:PRK11281   303 TL----TQQNLRVKNW---LDRLTQSERNIKEQISVLKGS 335
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 261-407 4.34e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 4.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  261 ADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDkkvENSNKEEIQEKETIIEELNTKIIE 340
Cdd:COG1579     31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG---NVRNNKEYEALQKEIESLKRRISD 107

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520  341 EEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELtnsKQKERQSSEEIKQLMGTVEELQKR 407
Cdd:COG1579    108 LEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL---DEELAELEAELEELEAEREELAAK 171
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 197-406 4.46e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 4.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  197 EAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETlrnsthsSTAADLLQAKQQIRTHQQQ 276
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEID-------KLQAEIAEAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  277 LEEQdhlLEDYQKKK---------------EDFTMQISFLQekikvyemeqdkKVENSNKEEIQEKETIIEELNTKIIEE 341
Cdd:COG3883     88 LGER---ARALYRSGgsvsyldvllgsesfSDFLDRLSALS------------KIADADADLLEELKADKAELEAKKAEL 152

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520  342 EKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQK 406
Cdd:COG3883    153 EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2032-2232 4.62e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2032 EHERDVFQQEIQKLEQQLKVVprfqpisehqTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVREL 2111
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAA----------QAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEER 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2112 EQAL-------------------LVSADTFQKV------------EDRKQFGAVEAkpelsLEVQLQAERDAIDRKEKEI 2160
Cdd:COG3883     85 REELgeraralyrsggsvsyldvLLGSESFSDFldrlsalskiadADADLLEELKA-----DKAELEAKKAELEAKLAEL 159

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622925520 2161 TNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAVSTQDQH 2232
Cdd:COG3883    160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2139-2361 5.07e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 5.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2139 ELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREEL-------------ENKNEEVQQLhMQLEIQKKESTTRLQELEQE 2205
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALeefrqknglvdlsEEAKLLLQQL-SELESQLAEARAELAEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2206 NKLFKDDMEklglaiKESDAVSTQDQHVLFGKFAQIIQEKEVEIDQL-------NEQIMKLQQQLKiTTDNKVIEEKNEL 2278
Cdd:COG3206    242 LAALRAQLG------SGPDALPELLQSPVIQQLRAQLAELEAELAELsarytpnHPDVIALRAQIA-ALRAQLQQEAQRI 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2279 IRDLETQIECLmsdqecvkrnrEEEIEQLNEVIEKLQQELANIGQKtLVDAHSLPEEADSLKHQLDMVIA--EKLALEQQ 2356
Cdd:COG3206    315 LASLEAELEAL-----------QAREASLQAQLAQLEARLAELPEL-EAELRRLEREVEVARELYESLLQrlEEARLAEA 382


                   ....*
gi 1622925520 2357 VETTN 2361
Cdd:COG3206    383 LTVGN 387
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 170-587 5.29e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 5.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  170 EIEELNRELEEMRVTYGTEglqqLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQaSE 249
Cdd:TIGR00606  692 ELQEFISDLQSKLRLAPDK----LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLK-ND 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  250 TLRNSTHSSTAADLLQAKQQIRTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSN----KEEIQ 325
Cdd:TIGR00606  767 IEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHEldtvVSKIE 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  326 EKETIIEELNTKIIEEEKKTLELKD---KLTAADKLLGELQEQVVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVE 402
Cdd:TIGR00606  847 LNRKLIQDQQEQIQHLKSKTNELKSeklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKE 926

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  403 ELQKRNHKDSQFETDIVQRMEQETQRK---LEQLRAELDEMYGQQIVQmKQELIRQHVSQMEELKTRHKGEMENALRSYP 479
Cdd:TIGR00606  927 ELISSKETSNKKAQDKVNDIKEKVKNIhgyMKDIENKIQDGKDDYLKQ-KETELNTVNAQLEECEKHQEKINEDMRLMRQ 1005

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  480 NITVNEDQIKLM--NVAINELNIKLQDTNSQKEKLKEELGV--ILEEKCALQRQLEDL-----FEELSFSREQIQRARQT 550
Cdd:TIGR00606 1006 DIDTQKIQERWLqdNLTLRKRENELKEVEEELKQHLKEMGQmqVLQMKQEHQKLEENIdlikrNHVLALGRQKGYEKEIK 1085

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1622925520  551 IAEQESKLNEAQKSLSTVEDLKAEIVSASESRKELEL 587
Cdd:TIGR00606 1086 HFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDI 1122
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1947-2552 5.52e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 5.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1947 QQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNAELMDLRQQNQALEKQLEKMRKFL-- 2024
Cdd:pfam15921  116 QTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILvd 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2025 -DEQAIDREHERDVF-----------------------------------QQEIQKLEQQLKVVPRFQP--------ISE 2060
Cdd:pfam15921  196 fEEASGKKIYEHDSMstmhfrslgsaiskilreldteisylkgrifpvedQLEALKSESQNKIELLLQQhqdrieqlISE 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2061 HQTrEVEQLTNHLKEKTDKCSELLLSKEQLQRDIQERNE----EIEKLEFRVRELEQALLVSADTFQKVEDRKQFGAVEA 2136
Cdd:pfam15921  276 HEV-EITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLA 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2137 KPELS---------------LEVQLQAERDAIDRKEKEITNLEEQ--------------LEQFREELENKNEEVQQLHMQ 2187
Cdd:pfam15921  355 NSELTearterdqfsqesgnLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEAL 434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2188 LEIQKKESTTRLQE-----------LEQENKL---FKDDMEKLGLAIKESDA--VSTQDQHVLFGKFAQIIQEKEVEIDQ 2251
Cdd:pfam15921  435 LKAMKSECQGQMERqmaaiqgknesLEKVSSLtaqLESTKEMLRKVVEELTAkkMTLESSERTVSDLTASLQEKERAIEA 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2252 LNEQIMKLQQQLKITTDN-KVIEEKNELIRDLETQIECLmsdqecvkrnrEEEIEQLNEVIEKLQQELANIGQktLVDAH 2330
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQElQHLKNEGDHLRNVQTECEAL-----------KLQMAEKDKVIEILRQQIENMTQ--LVGQH 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2331 SLPEEAdslkhqldmVIAEKLALEQQVETTNEEMTFTKNILKETNFKMNQLTQELFSLKreresMEKIQSIPGKSVNM-A 2409
Cdd:pfam15921  582 GRTAGA---------MQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEKVKLVNAGSERLrA 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2410 IDDMSKDKPEL--EVVLTEDALKSLENQtyLKSFEENGKGSIINLETRLLQLESTVRAKDLELTQCYKQIKDMQEQGQSE 2487
Cdd:pfam15921  648 VKDIKQERDQLlnEVKTSRNELNSLSED--YEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHA 725

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622925520 2488 IEVlqkkILNLQKILEEKVAaalvsqiQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDES 2552
Cdd:pfam15921  726 MKV----AMGMQKQITAKRG-------QIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELS 779
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
494-880 5.60e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 5.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  494 AINELNIKLQDTNSQKEKLKEELGVI--LEEKCALQRQLEDLFEELSFSREQIQRARQTIAEQESKLNEAQKSLSTVEDL 571
Cdd:COG4717     96 ELEELEEELEELEAELEELREELEKLekLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAEL 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  572 KAEIVSAsesRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEaELERLRTQLlfsheEELSKLKEDLEIEHQIN 651
Cdd:COG4717    176 QEELEEL---LEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQE-ELEELEEEL-----EQLENELEAAALEERLK 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  652 IEK--LKDNLGIHYKQQIDGLQNEMSQKI--------------ETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Cdd:COG4717    247 EARllLLIAAALLALLGLGGSLLSLILTIagvlflvlgllallFLLLAREKASLGKEAEELQALPALEELEEEELEELLA 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  716 EMTLQINELQKEIEILRQEEKEKGTLEQEVQEL--QLKIELLEKQMK--------EKENDLQEKFTQLEAENSiLKDEKK 785
Cdd:COG4717    327 ALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQLEELEQEIAallaeagvEDEEELRAALEQAEEYQE-LKEELE 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  786 ALEDMLKIHTPDNQEERLIFidsiksksKDSVWEKEIEILTEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEvnYQELQ 865
Cdd:COG4717    406 ELEEQLEELLGELEELLEAL--------DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE--LAELL 475

                          410
                   ....*....|....*
gi 1622925520  866 EEYACLLKVKDDLED 880
Cdd:COG4717    476 QELEELKAELRELAE 490
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 285-899 5.67e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 42.90  E-value: 5.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  285 EDYQKKK---EDFTMQISFLQEKIKVYEMEqDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTAADKLLGE 361
Cdd:PTZ00440  1123 EHYNKKKkslEKIYKQMEKTLKELENMNLE-DITLNEVNEIEIEYERILIDHIVEQINNEAKKSKTIMEEIESYKKDIDQ 1201

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  362 LQEQVVQKNQEIKNmKLELTNSKQKERQSSEEIKQLmgTVEELQKRNHKDSQFETDIVQRMEQET----------QRKLE 431
Cdd:PTZ00440  1202 VKKNMSKERNDHLT-TFEYNAYYDKATASYENIEEL--TTEAKGLKGEANRSTNVDELKEIKLQVfsylqqvikeNNKME 1278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  432 QLRAELDEMYGQQIVQMKQEL---IRQHVSQMEELKTRHKGEMENALRSYPNItvnEDQIKLMNVAINELNIKLQ----D 504
Cdd:PTZ00440  1279 NALHEIKNMYEFLISIDSEKIlkeILNSTKKAEEFSNDAKKELEKTDNLIKQV---EAKIEQAKEHKNKIYGSLEdkqiD 1355

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  505 TNSQK-EKLKEElgvILEEKCALQRQLEDLFEELSFSREQIQRARQTIAE---------------QESKLNEAQKSLSTV 568
Cdd:PTZ00440  1356 DEIKKiEQIKEE---ISNKRKEINKYLSNIKSNKEKCDLHVRNASRGKDKidflnkheaiepsnsKEVNIIKITDNINKC 1432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  569 EDLKAEIVSAS---ESRKELELKHEAEVTN---------YKIKLEMLEKEKNAVLDRMaesqEAELERLRTQLLFShEEE 636
Cdd:PTZ00440  1433 KQYSNEAMETEnkaDENNDSIIKYEKEITNilnnssilgKKTKLEKKKKEATNIMDDI----NGEHSIIKTKLTKS-SEK 1507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  637 LSKLKEdleiehQINIEKLKDNLgihykqqidglqNEMSQKIETMQFEKDNLITKQNqlILEISKLKDLQQSLVNSKSEE 716
Cdd:PTZ00440  1508 LNQLNE------QPNIKREGDVL------------NNDKSTIAYETIQYNLGRVKHN--LLNILNIKDEIETILNKAQDL 1567

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  717 M--TLQINELQKEIEILRQEEKekgtlEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIH 794
Cdd:PTZ00440  1568 MrdISKISKIVENKNLENLNDK-----EADYVKYLDNILKEKQLMEAEYKKLNEIYSDVDNIEKELKKHKKNYEIGLLEK 1642

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  795 TPDNQEERLIFIDSIKSKSKDSVwekEIEILTEENEDLKQQCIqlNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKV 874
Cdd:PTZ00440  1643 VIEINKNIKLYMDSTKESLNSLV---NNFSSLFNNFYLNKYNI--NENLEKYKKKLNEIYNEFMESYNIIQEKMKEVSND 1717

                          650       660
                   ....*....|....*....|....*
gi 1622925520  875 KDDLEDSKNKQELEYKSKLKALNEE 899
Cdd:PTZ00440  1718 DVDYNEAKTLREEAQKEEVNLNNKE 1742
PRK12704 PRK12704
phosphodiesterase; Provisional
 596-762 5.73e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  596 YKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHQINIEKLKDnlgihykqqidgLQNEMS 675
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQK------------LEKRLL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  676 QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLvNSKSEEMTLQINELQKEIEI---LRQEEKEKGTLEQEVQELQLKI 752
Cdd:PRK12704    93 QKEENLDRKLELLEKREEELEKKEKELEQKQQEL-EKKEEELEELIEEQLQELERisgLTAEEAKEILLEKVEEEARHEA 171

                          170
                   ....*....|
gi 1622925520  753 ELLEKQMKEK 762
Cdd:PRK12704   172 AVLIKEIEEE 181
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 597-847 6.03e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 6.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  597 KIKLEMLEKEKNAVLDRMAESQEAELERL-------RTQLLFSH----EEELSKLKEDLEIEHQINIEKLK------DNL 659
Cdd:PRK05771     8 KVLIVTLKSYKDEVLEALHELGVVHIEDLkeelsneRLRKLRSLltklSEALDKLRSYLPKLNPLREEKKKvsvkslEEL 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  660 GIHYKQQIDGLQNEMSQKIETMQfEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQI-NELQKEIEILRQEEKEK 738
Cdd:PRK05771    88 IKDVEEELEKIEKEIKELEEEIS-ELENEIKELEQEIERLEPWGNFDLDLSLLLGFKYVSVFvGTVPEDKLEELKLESDV 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  739 GTLEqEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKIhtpdnqEERLIFIDSIKSKSKdsvw 818
Cdd:PRK05771   167 ENVE-YISTDKGYVYVVVVVLKELSDEVEEELKKLGFERLELEEEGTPSELIREI------KEELEEIEKERESLL---- 235

                          250       260
                   ....*....|....*....|....*....
gi 1622925520  819 eKEIEILTEENEDLKQQCIQLNeEIEKQR 847
Cdd:PRK05771   236 -EELKELAKKYLEELLALYEYL-EIELER 262
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2924-3376 6.05e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 6.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2924 EDHSIQQISESWLEERKAYLSTISSLQDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSvlLAAFRTE 3003
Cdd:COG1196    324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--AAELAAQ 401

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3004 LTALGTTDAvGLLNCLEQRIQEQGVEYQAAMEYLQKADR-RSLLSEIQALHAQMNGRKITLKREQENEKSSQELLEYNIQ 3082
Cdd:COG1196    402 LEELEEAEE-ALLERLERLEEELEELEEALAELEEEEEEeEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3083 QKQSQMLEMQVELSSMKDRATELQEQLSSEKM------------VVAELRSELAQTKLELETTLKAQHKHL------KEL 3144
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAalllaglrglagAVAVLIGVEAAYEAALEAALAAALQNIvveddeVAA 560

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3145 EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQL 3224
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3225 LDESQQKIESQRM--LYDAQLSEEHGRNLELQVLLESEKVRIREMSSTLDRERELHAQlqsndgtgqsrpslpsEDLLKE 3302
Cdd:COG1196    641 TLAGRLREVTLEGegGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA----------------LLAEEE 704

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622925520 3303 LQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEE 3376
Cdd:COG1196    705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2980-3262 6.20e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 6.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2980 ELLLALQQVFLEERSVLLAAFRTELTALgtTDAVGLLNCLEQRIQEQGVEyqaameylQKADRRSLLSEIQALHAQMNGR 3059
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEEL--EEELEQLRKELEELSRQISA--------LRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3060 KITLKREQENEKSSQELLEyniqQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELRSELAQTKLELETTLKAQHK 3139
Cdd:TIGR02168  753 SKELTELEAEIEELEERLE----EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3140 HLKELEAFRLEV-------KDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGHSEER------DKEELEDLKFSLES 3206
Cdd:TIGR02168  829 LERRIAATERRLedleeqiEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAlallrsELEELSEELRELES 908

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622925520 3207 QKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQLSEEHGRNLELQVLLESEKV 3262
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1974-2356 6.46e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.50  E-value: 6.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1974 LQKQVKALEIDVEEQVSrfieLEQEKNAELMDLRQQNQALEKQLEKMRKFLDEqaidREHERDVFQQEIQKLEQQLK--- 2050
Cdd:pfam10174  343 LQTEVDALRLRLEEKES----FLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDV----KERKINVLQKKIENLQEQLRdkd 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2051 --------VVPRFQPISEHQTREVEQLTNHLKEKtDKCSELLlsKEQLQRDIQERNEEIEKLEFRVRELEQALlvsaDTF 2122
Cdd:pfam10174  415 kqlaglkeRVKSLQTDSSNTDTALTTLEEALSEK-ERIIERL--KEQREREDRERLEELESLKKENKDLKEKV----SAL 487

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2123 QKVEDRKQFGAVEAKPELSlevqlqAERDAIDRKEKEITNLEEQLEQFREE---LENKNEEVQQLHMQLEIqKKESTTRL 2199
Cdd:pfam10174  488 QPELTEKESSLIDLKEHAS------SLASSGLKKDSKLKSLEIAVEQKKEEcskLENQLKKAHNAEEAVRT-NPEINDRI 560

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2200 QELEQENKLFKDDMEKlglaikesdavSTQDQHVLFGKFAQIIQEK---EVEIDQLNEQIMKLQQQLKITTDNKVIEEKN 2276
Cdd:pfam10174  561 RLLEQEVARYKEESGK-----------AQAEVERLLGILREVENEKndkDKKIAELESLTLRQMKEQNKKVANIKHGQQE 629

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2277 ELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTLVDAHSLPEEA---DSLKHQLDMVIAEKLAL 2353
Cdd:pfam10174  630 MKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDghlTNLRAERRKQLEEILEM 709


                   ...
gi 1622925520 2354 EQQ 2356
Cdd:pfam10174  710 KQE 712
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1799-2196 7.37e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1799 LNISSRLQAAVEKLLEAISETSSQL--EHAKVTQTELMRESFRQKQEA---------TESLKCQEDLRERLHEESRAREQ 1867
Cdd:pfam01576  365 LEQAKRNKANLEKAKQALESENAELqaELRTLQQAKQDSEHKRKKLEGqlqelqarlSESERQRAELAEKLSKLQSELES 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1868 LAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQ 1947
Cdd:pfam01576  445 VSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQA 524

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 1948 QLlQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELE-------QEKNAELMDLRQQNQALEKQLEKM 2020
Cdd:pfam01576  525 QL-SDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEktknrlqQELDDLLVDLDHQRQLVSNLEKKQ 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2021 RKF----LDEQAIDREHERDVFQQEIQKLEQQLKVVPrfqpisehQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDIQE 2096
Cdd:pfam01576  604 KKFdqmlAEEKAISARYAEERDRAEAEAREKETRALS--------LARALEEALEAKEELERTNKQLRAEMEDLVSSKDD 675

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2097 RNEEIEKLEFRVRELEQALLVSADTFQKVEDRKQfGAVEAKpeLSLEVQLQAERDAIDRkekEITNLEEQLEQFREELen 2176
Cdd:pfam01576  676 VGKNVHELERSKRALEQQVEEMKTQLEELEDELQ-ATEDAK--LRLEVNMQALKAQFER---DLQARDEQGEEKRRQL-- 747

                          410       420
                   ....*....|....*....|
gi 1622925520 2177 kNEEVQQLHMQLEIQKKEST 2196
Cdd:pfam01576  748 -VKQVRELEAELEDERKQRA 766
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 3168-3400 7.81e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 7.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3168 EQKKSRELQWALEKEKAKLGHSEERDKE-----ELEDLKFSLESQKQRNLQLNLLLEQQKQLLDESQQKIESQRMLYDAQ 3242
Cdd:pfam17380  305 KEEKAREVERRRKLEEAEKARQAEMDRQaaiyaEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQ 384

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3243 LSEEHGRNLELQVLLESEKVRIREMsstlDRERELHAQLQSNDGTGQSRpslpsEDLLKELQKQLEEKHSRivellnETE 3322
Cdd:pfam17380  385 MERQQKNERVRQELEAARKVKILEE----ERQRKIQQQKVEMEQIRAEQ-----EEARQREVRRLEEERAR------EME 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 3323 KYKLDSLQTRQQMEKDRQ--VHRKTLQTEQEANTEGQKKMHELQSKVedLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQK 3400
Cdd:pfam17380  450 RVRLEEQERQQQVERLRQqeEERKRKKLELEKEKRDRKRAEEQRRKI--LEKELEERKQAMIEEERKRKLLEKEMEERQK 527
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 311-432 8.53e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 8.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520  311 EQDKKVENSNKEEIqekETIIEELNTKIIEEEKKTLELKDKLTAADKLLGELQEQVVQKNQEIKNMKLELtnskqkERQS 390
Cdd:PRK00409   505 EEAKKLIGEDKEKL---NELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEA------EKEA 575

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1622925520  391 SEEIKQLMGTVEELQKRNHKDSQFETDIVQRME-QETQRKLEQ 432
Cdd:PRK00409   576 QQAIKEAKKEADEIIKELRQLQKGGYASVKAHElIEARKRLNK 618
mukB PRK04863
chromosome partition protein MukB;
2088-2264 9.29e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 9.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2088 EQLQRDIQERNEEIEKLEFRVRELEQAllvsadtfqkVEDRKQFGAVEAKPELSL--EVQLQAERDAIDRKEKEITNLEE 2165
Cdd:PRK04863   789 EQLRAEREELAERYATLSFDVQKLQRL----------HQAFSRFIGSHLAVAFEAdpEAELRQLNRRRVELERALADHES 858

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520 2166 QLEQFREELENKNEEVQQLHM---QLEIQKKES-TTRLQELEQEnklfkddmeklgLAIKESDAVSTQDQHVLFGKFAQI 2241
Cdd:PRK04863   859 QEQQQRSQLEQAKEGLSALNRllpRLNLLADETlADRVEEIREQ------------LDEAEEAKRFVQQHGNALAQLEPI 926

                          170       180
                   ....*....|....*....|....*.
gi 1622925520 2242 ---IQEKEVEIDQLNEQIMKLQQQLK 2264
Cdd:PRK04863   927 vsvLQSDPEQFEQLKQDYQQAQQTQR 952
PRK12704 PRK12704
phosphodiesterase; Provisional
 715-788 9.40e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 9.40e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622925520  715 EEMTLQINELQKEIEILRQEE--KEKGTLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALE 788
Cdd:PRK12704    45 EEAKKEAEAIKKEALLEAKEEihKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELE 120
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 664-793 9.93e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 9.93e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622925520   664 KQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLV--------------NSKSEEMTLQINELQK--- 726
Cdd:smart00787  139 MKLLEGLKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEeelrqlkqledeleDCDPTELDRAKEKLKKllq 218

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622925520   727 EIEILRQEEKEkgtLEQEVQELQLKIELLEKQMKEKENDLQEKFTQLEAENSILKDEKKALEDMLKI 793
Cdd:smart00787  219 EIMIKVKKLEE---LEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKL 282
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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