NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1622923240|ref|XP_028701564|]
View 

LOW QUALITY PROTEIN: zinc finger protein 85-like [Macaca mulatta]

Protein Classification

KRAB domain-containing zinc finger protein( domain architecture ID 12204268)

KRAB (Kruppel-associated box) domain-containing zinc finger protein (KRAB-ZFP) plays important roles in cell differentiation and organ development, and in regulating viral replication and transcription

CATH:  3.30.160.60
Gene Ontology:  GO:0003700|GO:0046872
PubMed:  22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
4-63 3.29e-32

krueppel associated box;


:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 119.23  E-value: 3.29e-32
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240     4 LTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFLGIAICKPDLISCLEQEKEPW 63
Cdd:smart00349    1 VTFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPW 60
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
534-942 4.08e-15

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 79.35  E-value: 4.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  534 KPYKCEECGKAFN*SSALIGHKIIHTGEKPYKCEESG--KAFNLSSNLTAHKKIHLGEKPYKCE-ECGKAFNQSSTLTTH 610
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGcdKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  611 KIIHTEEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKMIHTGEKLykgdeCDKAFTRSST 690
Cdd:COG5048    112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  691 LTTHKIIHTGEKPYKCEECGKaFNGSSNLTEHKKIHTGEKSYKCEECGKAFNRSSNLTKHKKIHTGEKPYKCEECGKAFN 770
Cdd:COG5048    187 LISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  771 QFSTLTTHKIIHTGE-------KPYKCEECGKAFNLYVNLTTHK--KVHTGEK----SCKCEECGKAFNQVSTLTIDKRI 837
Cdd:COG5048    266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkpfSCPYSLCGKLFSRNDALKRHILL 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  838 HTGEKPYKCEECGKTFSQSSKLTTNK-------KIHTGEKPYKCE--KCGKAFNQSSTVSTHKIIHT--GEKCYKCEECG 906
Cdd:COG5048    346 HTSISPAKEKLLNSSSKFSPLLNNEPpqslqqyKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLsfRPYNCKNPPCS 425

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1622923240  907 KVFNRSSNLTEHKKIHTGEKSYKCEECGKAFNRSST 942
Cdd:COG5048    426 KSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDL 461
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-668 1.30e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 1.30e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  227 KPYKCKECGKAFNQTSHLVRHKRIHTEEKPYKCEECGRAFNQSST--LTTHNTIHTGGKPCKCEKCdrAFKQASKLTEHK 304
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPleLSRHLRTHHNNPSDLNSKS--LPLSNSKASSSS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  305 LIHTGEKP-YKCKECGKVFNQFSTFNTHKIIRTGEKPYECEEcgKAFN*SSKLTEhKCIHTGEKLYICEECGKAFNQSST 383
Cdd:COG5048    110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPL--PGNNSSSVNTP-QSNSLHPPLPANSLSKDPSSNLSL 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  384 LTTHKRIHSGEKPYKCEECGKAFKQSSNL*HKKIPTGEKPYKCEECGKAFN*SSNLTEHKKIHTAEKFYKCEECGKAFNQ 463
Cdd:COG5048    187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLP 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  464 LSNLTRHKLIHTGE-------KPYKCGEYGKAFNQSSALSAHK--IIHTGEN--PYKCRESGkvfhlssklstykkihtg 532
Cdd:COG5048    267 TASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkPFSCPYSL------------------ 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  533 ekpykceeCGKAFN*SSALIGHKIIHTGEKPYKC-------EESGKAFNLSSNLTAHKKIHLGEKPYKCE--ECGKAFNQ 603
Cdd:COG5048    329 --------CGKLFSRNDALKRHILLHTSISPAKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKR 400

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622923240  604 SSTLTTHKIIHT--EEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKM 668
Cdd:COG5048    401 DSNLSLHIITHLsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
4-63 3.29e-32

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 119.23  E-value: 3.29e-32
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240     4 LTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFLGIAICKPDLISCLEQEKEPW 63
Cdd:smart00349    1 VTFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPW 60
KRAB pfam01352
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ...
 3-44 5.29e-21

KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.


Pssm-ID: 460171  Cd Length: 42  Bit Score: 86.76  E-value: 5.29e-21
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1622923240    3 PLTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFLG 44
Cdd:pfam01352    1 SVTFEDVAVDFTQEEWALLDPAQRNLYRDVMLENYRNLVSLG 42
KRAB_A-box cd07765
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ...
 4-43 2.43e-18

KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation.


Pssm-ID: 143639  Cd Length: 40  Bit Score: 79.13  E-value: 2.43e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1622923240    4 LTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFL 43
Cdd:cd07765      1 VTFEDVAVYFSQEEWELLDPAQRDLYRDVMLENYENLVSL 40
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
534-942 4.08e-15

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 79.35  E-value: 4.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  534 KPYKCEECGKAFN*SSALIGHKIIHTGEKPYKCEESG--KAFNLSSNLTAHKKIHLGEKPYKCE-ECGKAFNQSSTLTTH 610
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGcdKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  611 KIIHTEEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKMIHTGEKLykgdeCDKAFTRSST 690
Cdd:COG5048    112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  691 LTTHKIIHTGEKPYKCEECGKaFNGSSNLTEHKKIHTGEKSYKCEECGKAFNRSSNLTKHKKIHTGEKPYKCEECGKAFN 770
Cdd:COG5048    187 LISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  771 QFSTLTTHKIIHTGE-------KPYKCEECGKAFNLYVNLTTHK--KVHTGEK----SCKCEECGKAFNQVSTLTIDKRI 837
Cdd:COG5048    266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkpfSCPYSLCGKLFSRNDALKRHILL 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  838 HTGEKPYKCEECGKTFSQSSKLTTNK-------KIHTGEKPYKCE--KCGKAFNQSSTVSTHKIIHT--GEKCYKCEECG 906
Cdd:COG5048    346 HTSISPAKEKLLNSSSKFSPLLNNEPpqslqqyKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLsfRPYNCKNPPCS 425

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1622923240  907 KVFNRSSNLTEHKKIHTGEKSYKCEECGKAFNRSST 942
Cdd:COG5048    426 KSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDL 461
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-668 1.30e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 1.30e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  227 KPYKCKECGKAFNQTSHLVRHKRIHTEEKPYKCEECGRAFNQSST--LTTHNTIHTGGKPCKCEKCdrAFKQASKLTEHK 304
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPleLSRHLRTHHNNPSDLNSKS--LPLSNSKASSSS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  305 LIHTGEKP-YKCKECGKVFNQFSTFNTHKIIRTGEKPYECEEcgKAFN*SSKLTEhKCIHTGEKLYICEECGKAFNQSST 383
Cdd:COG5048    110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPL--PGNNSSSVNTP-QSNSLHPPLPANSLSKDPSSNLSL 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  384 LTTHKRIHSGEKPYKCEECGKAFKQSSNL*HKKIPTGEKPYKCEECGKAFN*SSNLTEHKKIHTAEKFYKCEECGKAFNQ 463
Cdd:COG5048    187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLP 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  464 LSNLTRHKLIHTGE-------KPYKCGEYGKAFNQSSALSAHK--IIHTGEN--PYKCRESGkvfhlssklstykkihtg 532
Cdd:COG5048    267 TASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkPFSCPYSL------------------ 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  533 ekpykceeCGKAFN*SSALIGHKIIHTGEKPYKC-------EESGKAFNLSSNLTAHKKIHLGEKPYKCE--ECGKAFNQ 603
Cdd:COG5048    329 --------CGKLFSRNDALKRHILLHTSISPAKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKR 400

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622923240  604 SSTLTTHKIIHT--EEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKM 668
Cdd:COG5048    401 DSNLSLHIITHLsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
zf-H2C2_2 pfam13465
Zinc-finger double domain;
746-771 3.69e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.69e-04
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  746 NLTKHKKIHTGEKPYKCEECGKAFNQ 771
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
243-268 1.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.11e-03
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  243 HLVRHKRIHTEEKPYKCEECGRAFNQ 268
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
4-63 3.29e-32

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 119.23  E-value: 3.29e-32
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240     4 LTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFLGIAICKPDLISCLEQEKEPW 63
Cdd:smart00349    1 VTFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPW 60
KRAB pfam01352
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ...
 3-44 5.29e-21

KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.


Pssm-ID: 460171  Cd Length: 42  Bit Score: 86.76  E-value: 5.29e-21
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1622923240    3 PLTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFLG 44
Cdd:pfam01352    1 SVTFEDVAVDFTQEEWALLDPAQRNLYRDVMLENYRNLVSLG 42
KRAB_A-box cd07765
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ...
 4-43 2.43e-18

KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation.


Pssm-ID: 143639  Cd Length: 40  Bit Score: 79.13  E-value: 2.43e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1622923240    4 LTFMDVAIEFSLEEWECLDSAQQSLYRHVMLENYRNLVFL 43
Cdd:cd07765      1 VTFEDVAVYFSQEEWELLDPAQRDLYRDVMLENYENLVSL 40
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
534-942 4.08e-15

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 79.35  E-value: 4.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  534 KPYKCEECGKAFN*SSALIGHKIIHTGEKPYKCEESG--KAFNLSSNLTAHKKIHLGEKPYKCE-ECGKAFNQSSTLTTH 610
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGcdKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  611 KIIHTEEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKMIHTGEKLykgdeCDKAFTRSST 690
Cdd:COG5048    112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  691 LTTHKIIHTGEKPYKCEECGKaFNGSSNLTEHKKIHTGEKSYKCEECGKAFNRSSNLTKHKKIHTGEKPYKCEECGKAFN 770
Cdd:COG5048    187 LISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  771 QFSTLTTHKIIHTGE-------KPYKCEECGKAFNLYVNLTTHK--KVHTGEK----SCKCEECGKAFNQVSTLTIDKRI 837
Cdd:COG5048    266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkpfSCPYSLCGKLFSRNDALKRHILL 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  838 HTGEKPYKCEECGKTFSQSSKLTTNK-------KIHTGEKPYKCE--KCGKAFNQSSTVSTHKIIHT--GEKCYKCEECG 906
Cdd:COG5048    346 HTSISPAKEKLLNSSSKFSPLLNNEPpqslqqyKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLsfRPYNCKNPPCS 425

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1622923240  907 KVFNRSSNLTEHKKIHTGEKSYKCEECGKAFNRSST 942
Cdd:COG5048    426 KSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDL 461
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-668 1.30e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 1.30e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  227 KPYKCKECGKAFNQTSHLVRHKRIHTEEKPYKCEECGRAFNQSST--LTTHNTIHTGGKPCKCEKCdrAFKQASKLTEHK 304
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPleLSRHLRTHHNNPSDLNSKS--LPLSNSKASSSS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  305 LIHTGEKP-YKCKECGKVFNQFSTFNTHKIIRTGEKPYECEEcgKAFN*SSKLTEhKCIHTGEKLYICEECGKAFNQSST 383
Cdd:COG5048    110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPL--PGNNSSSVNTP-QSNSLHPPLPANSLSKDPSSNLSL 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  384 LTTHKRIHSGEKPYKCEECGKAFKQSSNL*HKKIPTGEKPYKCEECGKAFN*SSNLTEHKKIHTAEKFYKCEECGKAFNQ 463
Cdd:COG5048    187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLP 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  464 LSNLTRHKLIHTGE-------KPYKCGEYGKAFNQSSALSAHK--IIHTGEN--PYKCRESGkvfhlssklstykkihtg 532
Cdd:COG5048    267 TASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGESlkPFSCPYSL------------------ 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  533 ekpykceeCGKAFN*SSALIGHKIIHTGEKPYKC-------EESGKAFNLSSNLTAHKKIHLGEKPYKCE--ECGKAFNQ 603
Cdd:COG5048    329 --------CGKLFSRNDALKRHILLHTSISPAKEkllnsssKFSPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKR 400

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622923240  604 SSTLTTHKIIHT--EEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKM 668
Cdd:COG5048    401 DSNLSLHIITHLsfRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
339-752 2.25e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.58  E-value: 2.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  339 KPYECEECGKAFN*SSKLTEHKCIHTGEKLYICEECGKAFNQSST--LTTHKRIHSGEKPYKCEECGKAFKQSSNl*HKK 416
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPleLSRHLRTHHNNPSDLNSKSLPLSNSKAS-SSSL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  417 IPTGEKPYKCE-ECGKAFN*SSNLTEHKKIHTAEKFYKCEECGKAFNQLSNLTRHKLIHTGEKPYKCGEygkAFNQSSAL 495
Cdd:COG5048    111 SSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKD---PSSNLSLL 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  496 SAHKIIHTGENPYKCRESGKVFHLSSkLSTYKKIHTGEKPYKCEECGKAFN*SSALIGHKIIHTGEKPYKCEESGKAFNL 575
Cdd:COG5048    188 ISSNVSTSIPSSSENSPLSSSYSIPS-SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLP 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  576 SSNLTAHKKIHLGE-------KPYKCEECGKAFNQSSTLTTHK--IIHTEE--KQYKCDE--CGKAFTRSSKLIEHKKSH 642
Cdd:COG5048    267 TASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLH 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  643 TGEKPYKCEEC--------GKTSNNFSTFTKHKMIHTGEKLYK-GDECDKAFTRSSTLTTHKIIHTGEKP--YKCEECGK 711
Cdd:COG5048    347 TSISPAKEKLLnssskfspLLNNEPPQSLQQYKDLKNDKKSETlSNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSK 426

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1622923240  712 AFNGSSNLTEHKKIHTGEKSYKCEECGKaFNRSSNLTKHKK 752
Cdd:COG5048    427 SFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
452-857 2.33e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.58  E-value: 2.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  452 YKCEECGKAFNQLSNLTRHKLIHTGEKPYKCGEYGKAFNQS--SALSAHKIIHTGENPYkcRESGKVFHLSSKLSTYKKI 529
Cdd:COG5048     34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSSLS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  530 HTGEKPYKCE-ECGKAFN*SSALIGHKIIHTGEKPYKCEESGKAFNLSSNLTAHKKIHLGEKPYKCEECGKAFNQSSTLT 608
Cdd:COG5048    112 SSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  609 thkiIHTEEKQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGK------TSNNFSTFTKHKMIHTGEKLYKGDECD 682
Cdd:COG5048    192 ----VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQlspkslLSQSPSSLSSSDSSSSASESPRSSLPT 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  683 KAFTRSSTLTTHKIIHTG-EKPYKCEECGKAFNGSSNLTEHK--KIHTGE--KSYKCEE--CGKAFNRSSNLTKHKKIHT 755
Cdd:COG5048    268 ASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  756 GEKPYKC--EECGKAFNQFST-----LTTHKIIHTGEKPYKCE--ECGKAFNLYVNLTTHKKVHTGEKS--CKCEECGKA 824
Cdd:COG5048    348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1622923240  825 FNQVSTLTIDKRIHTGEKPYKCEECGKTFSQSS 857
Cdd:COG5048    428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
618-1026 1.89e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.88  E-value: 1.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  618 KQYKCDECGKAFTRSSKLIEHKKSHTGEKPYKC--EECGKTSNNFSTFTKHKMIHTGEKLYkgDECDKAFTRSSTLTTHK 695
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  696 IIHTGEKPYKCE-ECGKAFNGSSNLTEHKKIHTGEKSYKCEEcgKAFNRSSNLTKH--KKIHTGEKPykcEECGKAFNQF 772
Cdd:COG5048    110 LSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPL--PGNNSSSVNTPQsnSLHPPLPAN---SLSKDPSSNL 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  773 STLTTHKIIHTGEKPYKCEECGKaFNLYVNLTTHKKVHTGEKSCKCEECGKAF----NQVSTLTIDKRIHTGEKPYKCEE 848
Cdd:COG5048    185 SLLISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSpkslLSQSPSSLSSSDSSSSASESPRS 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  849 CGKT--FSQSSKLTTNKKIHTG-EKPYKCEKCGKAFNQSSTVSTHK--IIHTGEKCYKCEE----CGKVFNRSSNLTEHK 919
Cdd:COG5048    264 SLPTasSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGESLKPFSCpyslCGKLFSRNDALKRHI 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  920 KIHTGEKSYKC--EECGKAFNRSST--LTKYKVIHTGEKPYKCKE-----CGKAFKQFSHLAVHKIIHT--GEKLYKCEE 988
Cdd:COG5048    344 LLHTSISPAKEklLNSSSKFSPLLNnePPQSLQQYKDLKNDKKSEtlsnsCIRNFKRDSNLSLHIITHLsfRPYNCKNPP 423

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1622923240  989 RGKAFNLSSNLTAHKKNHTGVKPYKCEECGKANLSSTL 1026
Cdd:COG5048    424 CSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDL 461
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
400-811 4.48e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 69.72  E-value: 4.48e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  400 EECGKAFKQSSNL*HKKIPTGEKPYKCEECGKAFN*SSNLTEHKKIHTAEKFYKC--EECGKAFNQLSNLTRHKLIHTGE 477
Cdd:COG5048     10 SSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  478 KPYKC------GEYGKAFNQSSALSAHKIIHTGENPYKCRESGKVFHLSSKLSTYKKIHTGEKPYKcEECGKAFN*SSAL 551
Cdd:COG5048     90 PSDLNskslplSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNN-SSSVNTPQSNSLH 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  552 IGHKIIHTGEKPYKCEESGKAFNLSSNLTAHKKIHLGEKPYKceecgkafnQSSTLTTHKIIHTEEKqYKCDECGKAFTR 631
Cdd:COG5048    169 PPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYS---------IPSSSSDQNLENSSSS-LPLTTNSQLSPK 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  632 SSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFTKHKMIHTGE-------KLYKGDECDKAFTRSSTLTTHK--IIHTGE- 701
Cdd:COG5048    239 SLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEs 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  702 -KPYKCEE--CGKAFNGSSNLTEHKKIHTGEKSYKC--EECGKAFNRSSN-----LTKHKKIHTGEKPYKCE--ECGKAF 769
Cdd:COG5048    319 lKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNF 398

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1622923240  770 NQFSTLTTHKIIHTGEKP--YKCEECGKAFNLYVNLTTHKKVHT 811
Cdd:COG5048    399 KRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
201-611 3.97e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 3.97e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  201 YKYEECGRAFNWSSTLNKHKRIHMREKPYKC--KECGKAFNQTSHLVRHKRIHTEEKPYKCEECGRAFNQSSTLTTHNTI 278
Cdd:COG5048     34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLSSS 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  279 HTGG-KPCKCEKCDRAFKQASKLTEHKLIHTGEKPYKCKEC-GKVFNQFSTFNTHKIIRTGEKPYECEECGKAFN*SSKL 356
Cdd:COG5048    114 SSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSNVS 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  357 TEHKCIhtgeklYICEECGKAFNQSSTLTTHKRIHSgEKPYKCEECGKAFKQSSNL*-HKKIPTGEKPYKCEECGKAFN* 435
Cdd:COG5048    194 TSIPSS------SENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQsPSSLSSSDSSSSASESPRSSLP 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  436 SSNLTEHKKIHTAE-------KFYKCEECGKAFNQLSNLTRHK--LIHTGE--KPYKCGE--YGKAFNQSSALSAHKIIH 502
Cdd:COG5048    267 TASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLH 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  503 TGENPYKCR-------ESGKVFHLSSKLSTYKKIHTGEKPYKCE--ECGKAFN*SSALIGHKIIHTGEKPYKCEESG--K 571
Cdd:COG5048    347 TSISPAKEKllnssskFSPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKNPPcsK 426

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1622923240  572 AFNLSSNLTAHKKIHLGEKPYKCEECGKAFNQSSTLTTHK 611
Cdd:COG5048    427 SFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
171-332 1.88e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.07  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  171 KHFKCKECGKTFCMLSHLTQHKR--IHIRVNFY----KYEECGRAFNWSSTLNKHKRIHMREKPYKCKEC------GKAF 238
Cdd:COG5048    288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGESLKpfscPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfSPLL 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  239 NQTSHLVRHKRIHTEEKPYKC---EECGRAFNQSSTLTTHNTIHTGGKP--CKCEKCDRAFKQASKLTEHKLIHTGEKPY 313
Cdd:COG5048    368 NNEPPQSLQQYKDLKNDKKSEtlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPL 447

                          170
                   ....*....|....*....
gi 1622923240  314 KCKECGKVFNQFSTFNTHK 332
Cdd:COG5048    448 LCSILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
746-771 3.69e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.69e-04
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  746 NLTKHKKIHTGEKPYKCEECGKAFNQ 771
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 700-779 6.68e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.55  E-value: 6.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  700 GEKPYKCE--ECGKAFNGSSNLTEHKKihTGEKSYKCEEcgkafnrSSNLTKHKKIHTGEKPYKCEECGKAFNQFSTLTT 777
Cdd:COG5189    346 DGKPYKCPveGCNKKYKNQNGLKYHML--HGHQNQKLHE-------NPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                   ..
gi 1622923240  778 HK 779
Cdd:COG5189    417 HR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 644-724 1.01e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  644 GEKPYKCE--ECGKTSNNfSTFTKHKMIHtgeklykgDECDKAFTRSSTLTTHKIIHTGEKPYKCEECGKAFNGSSNLTE 721
Cdd:COG5189    346 DGKPYKCPveGCNKKYKN-QNGLKYHMLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                   ...
gi 1622923240  722 HKK 724
Cdd:COG5189    417 HRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
243-268 1.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.11e-03
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  243 HLVRHKRIHTEEKPYKCEECGRAFNQ 268
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
384-408 1.47e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.47e-03
                           10        20
                   ....*....|....*....|....*
gi 1622923240  384 LTTHKRIHSGEKPYKCEECGKAFKQ 408
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
914-939 1.77e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.77e-03
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  914 NLTEHKKIHTGEKSYKCEECGKAFNR 939
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
718-743 1.77e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.77e-03
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  718 NLTEHKKIHTGEKSYKCEECGKAFNR 743
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
216-240 2.29e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.29e-03
                           10        20
                   ....*....|....*....|....*
gi 1622923240  216 LNKHKRIHMREKPYKCKECGKAFNQ 240
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 587-667 2.48e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 2.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622923240  587 LGEKPYKCE--ECGKAFNQSSTLTTHKiihteekqyKCDECGKAFTRSSKLIEHKKSHTGEKPYKCEECGKTSNNFSTFT 664
Cdd:COG5189    345 KDGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                   ...
gi 1622923240  665 KHK 667
Cdd:COG5189    416 YHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
578-603 3.86e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 3.86e-03
                           10        20
                   ....*....|....*....|....*.
gi 1622923240  578 NLTAHKKIHLGEKPYKCEECGKAFNQ 603
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 393-444 4.86e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 4.86e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622923240  393 GEKPYKCE--ECGKAFKQSSNL*-HKK--------------IPT-----GEKPYKCEECGKAFN*SSNLTEHKK 444
Cdd:COG5189    346 DGKPYKCPveGCNKKYKNQNGLKyHMLhghqnqklhenpspEKMnifsaKDKPYRCEVCDKRYKNLNGLKYHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
300-324 6.24e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.24e-03
                           10        20
                   ....*....|....*....|....*
gi 1622923240  300 LTEHKLIHTGEKPYKCKECGKVFNQ 324
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
691-714 7.90e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 7.90e-03
                           10        20
                   ....*....|....*....|....
gi 1622923240  691 LTTHKIIHTGEKPYKCEECGKAFN 714
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
775-798 7.90e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 7.90e-03
                           10        20
                   ....*....|....*....|....
gi 1622923240  775 LTTHKIIHTGEKPYKCEECGKAFN 798
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFK 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH