zinc finger protein 862 isoform X2 [Macaca mulatta]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| ZnF_TTF | smart00597 | zinc finger in transposases and transcription factors; |
128-211 | 1.69e-26 | ||||
zinc finger in transposases and transcription factors; : Pssm-ID: 214739 Cd Length: 91 Bit Score: 104.11 E-value: 1.69e-26
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| ZnF_TTF super family | cl02692 | zinc finger in transposases and transcription factors; |
486-569 | 1.03e-22 | ||||
zinc finger in transposases and transcription factors; The actual alignment was detected with superfamily member smart00597: Pssm-ID: 214739 Cd Length: 91 Bit Score: 93.32 E-value: 1.03e-22
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| KRAB | smart00349 | krueppel associated box; |
326-417 | 2.22e-22 | ||||
krueppel associated box; : Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 91.50 E-value: 2.22e-22
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| KRAB super family | cl42959 | krueppel associated box; |
4-58 | 2.96e-09 | ||||
krueppel associated box; The actual alignment was detected with superfamily member smart00349: Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 54.14 E-value: 2.96e-09
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| DUF4371 super family | cl46273 | Domain of unknown function (DUF4371); |
528-732 | 8.06e-08 | ||||
Domain of unknown function (DUF4371); The actual alignment was detected with superfamily member pfam14291: Pssm-ID: 480613 Cd Length: 236 Bit Score: 54.54 E-value: 8.06e-08
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| Dimer_Tnp_hAT super family | cl05324 | hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ... |
1041-1091 | 5.30e-05 | ||||
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro. The actual alignment was detected with superfamily member pfam05699: Pssm-ID: 399013 Cd Length: 83 Bit Score: 42.63 E-value: 5.30e-05
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| Name | Accession | Description | Interval | E-value | ||||
| ZnF_TTF | smart00597 | zinc finger in transposases and transcription factors; |
128-211 | 1.69e-26 | ||||
zinc finger in transposases and transcription factors; Pssm-ID: 214739 Cd Length: 91 Bit Score: 104.11 E-value: 1.69e-26
|
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| ZnF_TTF | smart00597 | zinc finger in transposases and transcription factors; |
486-569 | 1.03e-22 | ||||
zinc finger in transposases and transcription factors; Pssm-ID: 214739 Cd Length: 91 Bit Score: 93.32 E-value: 1.03e-22
|
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| KRAB | smart00349 | krueppel associated box; |
326-417 | 2.22e-22 | ||||
krueppel associated box; Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 91.50 E-value: 2.22e-22
|
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| KRAB | pfam01352 | KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ... |
325-366 | 3.74e-18 | ||||
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation. Pssm-ID: 460171 Cd Length: 42 Bit Score: 78.67 E-value: 3.74e-18
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| KRAB_A-box | cd07765 | KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ... |
328-365 | 8.39e-17 | ||||
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation. Pssm-ID: 143639 Cd Length: 40 Bit Score: 74.89 E-value: 8.39e-17
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| KRAB | smart00349 | krueppel associated box; |
4-58 | 2.96e-09 | ||||
krueppel associated box; Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 54.14 E-value: 2.96e-09
|
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| DUF4371 | pfam14291 | Domain of unknown function (DUF4371); |
528-732 | 8.06e-08 | ||||
Domain of unknown function (DUF4371); Pssm-ID: 405048 Cd Length: 236 Bit Score: 54.54 E-value: 8.06e-08
|
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| KRAB_A-box | cd07765 | KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ... |
4-29 | 4.74e-07 | ||||
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation. Pssm-ID: 143639 Cd Length: 40 Bit Score: 47.16 E-value: 4.74e-07
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| KRAB | pfam01352 | KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ... |
3-29 | 5.23e-07 | ||||
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation. Pssm-ID: 460171 Cd Length: 42 Bit Score: 47.08 E-value: 5.23e-07
|
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| Dimer_Tnp_hAT | pfam05699 | hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ... |
1041-1091 | 5.30e-05 | ||||
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro. Pssm-ID: 399013 Cd Length: 83 Bit Score: 42.63 E-value: 5.30e-05
|
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| Name | Accession | Description | Interval | E-value | ||||
| ZnF_TTF | smart00597 | zinc finger in transposases and transcription factors; |
128-211 | 1.69e-26 | ||||
zinc finger in transposases and transcription factors; Pssm-ID: 214739 Cd Length: 91 Bit Score: 104.11 E-value: 1.69e-26
|
||||||||
| ZnF_TTF | smart00597 | zinc finger in transposases and transcription factors; |
486-569 | 1.03e-22 | ||||
zinc finger in transposases and transcription factors; Pssm-ID: 214739 Cd Length: 91 Bit Score: 93.32 E-value: 1.03e-22
|
||||||||
| KRAB | smart00349 | krueppel associated box; |
326-417 | 2.22e-22 | ||||
krueppel associated box; Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 91.50 E-value: 2.22e-22
|
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| KRAB | pfam01352 | KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ... |
325-366 | 3.74e-18 | ||||
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation. Pssm-ID: 460171 Cd Length: 42 Bit Score: 78.67 E-value: 3.74e-18
|
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| KRAB_A-box | cd07765 | KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ... |
328-365 | 8.39e-17 | ||||
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation. Pssm-ID: 143639 Cd Length: 40 Bit Score: 74.89 E-value: 8.39e-17
|
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| KRAB | smart00349 | krueppel associated box; |
4-58 | 2.96e-09 | ||||
krueppel associated box; Pssm-ID: 214630 [Multi-domain] Cd Length: 61 Bit Score: 54.14 E-value: 2.96e-09
|
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| DUF4371 | pfam14291 | Domain of unknown function (DUF4371); |
528-732 | 8.06e-08 | ||||
Domain of unknown function (DUF4371); Pssm-ID: 405048 Cd Length: 236 Bit Score: 54.54 E-value: 8.06e-08
|
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| KRAB_A-box | cd07765 | KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ... |
4-29 | 4.74e-07 | ||||
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation. Pssm-ID: 143639 Cd Length: 40 Bit Score: 47.16 E-value: 4.74e-07
|
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| KRAB | pfam01352 | KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ... |
3-29 | 5.23e-07 | ||||
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation. Pssm-ID: 460171 Cd Length: 42 Bit Score: 47.08 E-value: 5.23e-07
|
||||||||
| Dimer_Tnp_hAT | pfam05699 | hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ... |
1041-1091 | 5.30e-05 | ||||
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro. Pssm-ID: 399013 Cd Length: 83 Bit Score: 42.63 E-value: 5.30e-05
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| Blast search parameters | ||||
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