|
Name |
Accession |
Description |
Interval |
E-value |
| Muskelin_N |
pfam06588 |
Muskelin N-terminus; This family represents the N-terminal region of muskelin and is found in ... |
12-207 |
4.73e-124 |
|
Muskelin N-terminus; This family represents the N-terminal region of muskelin and is found in conjunction with several pfam01344 repeats. Muskelin is an intracellular, kelch repeat protein that is needed in cell-spreading responses to the matrix adhesion molecule, thrombospondin-1.
Pssm-ID: 284099 Cd Length: 197 Bit Score: 366.84 E-value: 4.73e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 12 ECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFG 91
Cdd:pfam06588 1 EYSVLPYEIHSYSSYSSVYLPENILVDDPNDQNSRWSTSTNSPPQYLILKLPRPAIVTTITFGKYEKMHVCNLKKFRVYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 92 GMNEENMTELLSSGLKNDYNKETFTLKHKI-DEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDVVQPCLNWYSK 170
Cdd:pfam06588 81 GRDGEEMRELLCGGLKNDSNMETFNLLVKDyNEIYFPCQYIKIVPLLAWGPSFNFSIWYVELHGIDDPSAVSEFVKNYEM 160
|
170 180 190
....*....|....*....|....*....|....*..
gi 1622918265 171 YREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHP 207
Cdd:pfam06588 161 VREGEAIRLCLKHFRQCGYLDIFEILQKRTSDKIEHP 197
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
284-608 |
2.18e-12 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 67.87 E-value: 2.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 284 TVYLFGGWDGTQDLADFWAYSVKENQWtcisrdTEKENGPSARSCHKMCIdIQRRQIYTLGRYldSSVRNSKSLKSDFYR 363
Cdd:COG3055 24 KVYVAGGLSGGSASNSFEVYDPATNTW------SELAPLPGPPRHHAAAV-AQDGKLYVFGGF--TGANPSSTPLNDVYV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 364 YDIDTNTWmllsedTAADGGPKLVFDHQMCMDSEKhmIYTFGGRilTCNGSVDDsrasepqfsgLFAFNCQCQTWKLLre 443
Cdd:COG3055 95 YDPATNTW------TKLAPMPTPRGGATALLLDGK--IYVVGGW--DDGGNVAW----------VEVYDPATGTWTQL-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 444 dscnagPEDIQSRIGHCMLFHSKNRcLYVFGGQRSktylndffsydvdsdhvdiiSDGTKKDSGMVPMTGFTQRATIDPE 523
Cdd:COG3055 153 ------APLPTPRDHLAAAVLPDGK-ILVIGGRNG--------------------SGFSNTWTTLAPLPTARAGHAAAVL 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 524 LNEIHVLSGlskdkekrEENVRNSFWIYDIVRNSWScvykndqAAKDNPTkslqeeepcPRFAHQLV-YDElhKVhYLFG 602
Cdd:COG3055 206 GGKILVFGG--------ESGFSDEVEAYDPATNTWT-------ALGELPT---------PRHGHAAVlTDG--KV-YVIG 258
|
....*...
gi 1622918265 603 G--NPGKS 608
Cdd:COG3055 259 GetKPGVR 266
|
|
| Kelch_3 |
pfam13415 |
Galactose oxidase, central domain; |
282-334 |
3.72e-07 |
|
Galactose oxidase, central domain;
Pssm-ID: 433188 [Multi-domain] Cd Length: 49 Bit Score: 47.28 E-value: 3.72e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1622918265 282 TETVYLFGGWD--GTQDLADFWAYSVKENQWTCISrdtekeNGPSARSCHKMCID 334
Cdd:pfam13415 1 GDKLYIFGGLGfdGQTRLNDLYVYDLDTNTWTQIG------DLPPPRSGHSATYI 49
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
307-475 |
1.31e-06 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 51.14 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 307 ENQWtcISRDTEKENGPSARSCHKMCIdiQRRQIYTLGryldSSVRNSKSLKSDFYRYDIDTNTWMLlsedTAADGGPKL 386
Cdd:PLN02153 6 QGGW--IKVEQKGGKGPGPRCSHGIAV--VGDKLYSFG----GELKPNEHIDKDLYVFDFNTHTWSI----APANGDVPR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 387 VFDHQMCMDSEKHMIYTFGGRiltcngsvDDSRAsepqFSGLFAFNCQCQTWKLLREDSCNAGPEdiqSRIGHCMLfhSK 466
Cdd:PLN02153 74 ISCLGVRMVAVGTKLYIFGGR--------DEKRE----FSDFYSYDTVKNEWTFLTKLDEEGGPE---ARTFHSMA--SD 136
|
....*....
gi 1622918265 467 NRCLYVFGG 475
Cdd:PLN02153 137 ENHVYVFGG 145
|
|
| Kelch |
smart00612 |
Kelch domain; |
285-311 |
1.30e-03 |
|
Kelch domain;
Pssm-ID: 128874 [Multi-domain] Cd Length: 47 Bit Score: 37.15 E-value: 1.30e-03
|
| LisH |
smart00667 |
Lissencephaly type-1-like homology motif; Alpha-helical motif present in Lis1, treacle, ... |
172-202 |
8.64e-03 |
|
Lissencephaly type-1-like homology motif; Alpha-helical motif present in Lis1, treacle, Nopp140, some katanin p60 subunits, muskelin, tonneau, LEUNIG and numerous WD40 repeat-containing proteins. It is suggested that LisH motifs contribute to the regulation of microtubule dynamics, either by mediating dimerisation, or else by binding cytoplasmic dynein heavy chain or microtubules directly.
Pssm-ID: 128913 Cd Length: 34 Bit Score: 34.33 E-value: 8.64e-03
10 20 30
....*....|....*....|....*....|.
gi 1622918265 172 REQEAIRLCLKHFRQHNYTEAFESLQKKTKI 202
Cdd:smart00667 2 SRSELNRLILEYLLRNGYEETAETLQKESGL 32
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Muskelin_N |
pfam06588 |
Muskelin N-terminus; This family represents the N-terminal region of muskelin and is found in ... |
12-207 |
4.73e-124 |
|
Muskelin N-terminus; This family represents the N-terminal region of muskelin and is found in conjunction with several pfam01344 repeats. Muskelin is an intracellular, kelch repeat protein that is needed in cell-spreading responses to the matrix adhesion molecule, thrombospondin-1.
Pssm-ID: 284099 Cd Length: 197 Bit Score: 366.84 E-value: 4.73e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 12 ECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFG 91
Cdd:pfam06588 1 EYSVLPYEIHSYSSYSSVYLPENILVDDPNDQNSRWSTSTNSPPQYLILKLPRPAIVTTITFGKYEKMHVCNLKKFRVYG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 92 GMNEENMTELLSSGLKNDYNKETFTLKHKI-DEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDVVQPCLNWYSK 170
Cdd:pfam06588 81 GRDGEEMRELLCGGLKNDSNMETFNLLVKDyNEIYFPCQYIKIVPLLAWGPSFNFSIWYVELHGIDDPSAVSEFVKNYEM 160
|
170 180 190
....*....|....*....|....*....|....*..
gi 1622918265 171 YREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHP 207
Cdd:pfam06588 161 VREGEAIRLCLKHFRQCGYLDIFEILQKRTSDKIEHP 197
|
|
| NanM |
COG3055 |
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis]; |
284-608 |
2.18e-12 |
|
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442289 [Multi-domain] Cd Length: 277 Bit Score: 67.87 E-value: 2.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 284 TVYLFGGWDGTQDLADFWAYSVKENQWtcisrdTEKENGPSARSCHKMCIdIQRRQIYTLGRYldSSVRNSKSLKSDFYR 363
Cdd:COG3055 24 KVYVAGGLSGGSASNSFEVYDPATNTW------SELAPLPGPPRHHAAAV-AQDGKLYVFGGF--TGANPSSTPLNDVYV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 364 YDIDTNTWmllsedTAADGGPKLVFDHQMCMDSEKhmIYTFGGRilTCNGSVDDsrasepqfsgLFAFNCQCQTWKLLre 443
Cdd:COG3055 95 YDPATNTW------TKLAPMPTPRGGATALLLDGK--IYVVGGW--DDGGNVAW----------VEVYDPATGTWTQL-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 444 dscnagPEDIQSRIGHCMLFHSKNRcLYVFGGQRSktylndffsydvdsdhvdiiSDGTKKDSGMVPMTGFTQRATIDPE 523
Cdd:COG3055 153 ------APLPTPRDHLAAAVLPDGK-ILVIGGRNG--------------------SGFSNTWTTLAPLPTARAGHAAAVL 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 524 LNEIHVLSGlskdkekrEENVRNSFWIYDIVRNSWScvykndqAAKDNPTkslqeeepcPRFAHQLV-YDElhKVhYLFG 602
Cdd:COG3055 206 GGKILVFGG--------ESGFSDEVEAYDPATNTWT-------ALGELPT---------PRHGHAAVlTDG--KV-YVIG 258
|
....*...
gi 1622918265 603 G--NPGKS 608
Cdd:COG3055 259 GetKPGVR 266
|
|
| F5_F8_type_C |
pfam00754 |
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family. |
24-152 |
8.94e-09 |
|
F5/8 type C domain; This domain is also known as the discoidin (DS) domain family.
Pssm-ID: 459925 [Multi-domain] Cd Length: 127 Bit Score: 53.99 E-value: 8.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 24 SSFSSTYLPENiLVDkpNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLS 103
Cdd:pfam00754 6 SSYSGEGPAAA-ALD--GDPNTAWSAWSGDDPQWIQVDLGKPKKITGVVTQGRQDGSNGYVTSYKIEYSLDGENWTTVKD 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1622918265 104 SGLKNDYNKETftlkhkIDEQMFPC----RFIKIVPlLSWGPSFNFSIWyVEL 152
Cdd:pfam00754 83 EKIPGNNDNNT------PVTNTFDPpikaRYVRIVP-TSWNGGNGIALR-AEL 127
|
|
| Kelch_3 |
pfam13415 |
Galactose oxidase, central domain; |
282-334 |
3.72e-07 |
|
Galactose oxidase, central domain;
Pssm-ID: 433188 [Multi-domain] Cd Length: 49 Bit Score: 47.28 E-value: 3.72e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1622918265 282 TETVYLFGGWD--GTQDLADFWAYSVKENQWTCISrdtekeNGPSARSCHKMCID 334
Cdd:pfam13415 1 GDKLYIFGGLGfdGQTRLNDLYVYDLDTNTWTQIG------DLPPPRSGHSATYI 49
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
307-475 |
1.31e-06 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 51.14 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 307 ENQWtcISRDTEKENGPSARSCHKMCIdiQRRQIYTLGryldSSVRNSKSLKSDFYRYDIDTNTWMLlsedTAADGGPKL 386
Cdd:PLN02153 6 QGGW--IKVEQKGGKGPGPRCSHGIAV--VGDKLYSFG----GELKPNEHIDKDLYVFDFNTHTWSI----APANGDVPR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 387 VFDHQMCMDSEKHMIYTFGGRiltcngsvDDSRAsepqFSGLFAFNCQCQTWKLLREDSCNAGPEdiqSRIGHCMLfhSK 466
Cdd:PLN02153 74 ISCLGVRMVAVGTKLYIFGGR--------DEKRE----FSDFYSYDTVKNEWTFLTKLDEEGGPE---ARTFHSMA--SD 136
|
....*....
gi 1622918265 467 NRCLYVFGG 475
Cdd:PLN02153 137 ENHVYVFGG 145
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
285-376 |
4.58e-06 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 49.21 E-value: 4.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 285 VYLFGGWDGTQDLADFWAYSVKENQWTCISRdTEKENGPSARSCHKMCIDiqRRQIYTLGRYLDSSVRNSKSLKSDFYRY 364
Cdd:PLN02153 88 LYIFGGRDEKREFSDFYSYDTVKNEWTFLTK-LDEEGGPEARTFHSMASD--ENHVYVFGGVSKGGLMKTPERFRTIEAY 164
|
90
....*....|..
gi 1622918265 365 DIDTNTWMLLSE 376
Cdd:PLN02153 165 NIADGKWVQLPD 176
|
|
| Kelch_1 |
pfam01344 |
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ... |
270-314 |
4.69e-06 |
|
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.
Pssm-ID: 396078 [Multi-domain] Cd Length: 46 Bit Score: 43.75 E-value: 4.69e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1622918265 270 MRGGHQMVidVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCIS 314
Cdd:pfam01344 1 RRSGAGVV--VVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLP 43
|
|
| PLN02193 |
PLN02193 |
nitrile-specifier protein |
284-386 |
1.04e-04 |
|
nitrile-specifier protein
Pssm-ID: 177844 [Multi-domain] Cd Length: 470 Bit Score: 45.33 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 284 TVYLFGGWDGTQDLADFWAYSVKENQWTCIsrdTEKENGPSARSCHKMCIDiqRRQIYTLGRYldSSVRNSKSLKSdfyr 363
Cdd:PLN02193 230 TLYVFGGRDASRQYNGFYSFDTTTNEWKLL---TPVEEGPTPRSFHSMAAD--EENVYVFGGV--SATARLKTLDS---- 298
|
90 100
....*....|....*....|....*.
gi 1622918265 364 YDIDTNTWMLLS---EDTAADGGPKL 386
Cdd:PLN02193 299 YNIVDKKWFHCStpgDSFSIRGGAGL 324
|
|
| PLN02153 |
PLN02153 |
epithiospecifier protein |
371-558 |
2.29e-04 |
|
epithiospecifier protein
Pssm-ID: 177814 [Multi-domain] Cd Length: 341 Bit Score: 43.82 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 371 WMLLSEDTAADGGPKLvfDHQMCMDSEKhmIYTFGGRiLTCNGSVDDSrasepqfsgLFAFNCQCQTWKLLredSCNAGP 450
Cdd:PLN02153 9 WIKVEQKGGKGPGPRC--SHGIAVVGDK--LYSFGGE-LKPNEHIDKD---------LYVFDFNTHTWSIA---PANGDV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 451 EDIqSRIGHCMLfhSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIIsdgTKKDSGMVPMTGFTQRATIDPelNEIHVL 530
Cdd:PLN02153 72 PRI-SCLGVRMV--AVGTKLYIFGGRDEKREFSDFYSYDTVKNEWTFL---TKLDEEGGPEARTFHSMASDE--NHVYVF 143
|
170 180
....*....|....*....|....*...
gi 1622918265 531 SGLSKDKEKREENVRNSFWIYDIVRNSW 558
Cdd:PLN02153 144 GGVSKGGLMKTPERFRTIEAYNIADGKW 171
|
|
| Kelch_4 |
pfam13418 |
Galactose oxidase, central domain; |
271-314 |
4.00e-04 |
|
Galactose oxidase, central domain;
Pssm-ID: 433191 [Multi-domain] Cd Length: 49 Bit Score: 38.75 E-value: 4.00e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1622918265 271 RGGHQMVIdVQTETVYLFGG--WDGTQdLADFWAYSVKENQWTCIS 314
Cdd:pfam13418 2 RAYHTSTS-IPDDTIYLFGGegEDGTL-LSDLWVFDLSTNEWTRLG 45
|
|
| PLN02193 |
PLN02193 |
nitrile-specifier protein |
383-558 |
5.65e-04 |
|
nitrile-specifier protein
Pssm-ID: 177844 [Multi-domain] Cd Length: 470 Bit Score: 43.02 E-value: 5.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 383 GPKLVFDHQMCMDSEKhmIYTFGGRiLTCNGSVDDSrasepqfsgLFAFNCQCQTWKLlredSCNAGPEDIQSRIGHCML 462
Cdd:PLN02193 162 GPGLRCSHGIAQVGNK--IYSFGGE-FTPNQPIDKH---------LYVFDLETRTWSI----SPATGDVPHLSCLGVRMV 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622918265 463 fhSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIIsdgTKKDSGMVPMTGFTQRAtidpELNEIHVLSGLSKdkekree 542
Cdd:PLN02193 226 --SIGSTLYVFGGRDASRQYNGFYSFDTTTNEWKLL---TPVEEGPTPRSFHSMAA----DEENVYVFGGVSA------- 289
|
170
....*....|....*..
gi 1622918265 543 NVR-NSFWIYDIVRNSW 558
Cdd:PLN02193 290 TARlKTLDSYNIVDKKW 306
|
|
| Kelch_1 |
pfam01344 |
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ... |
456-493 |
1.08e-03 |
|
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.
Pssm-ID: 396078 [Multi-domain] Cd Length: 46 Bit Score: 37.21 E-value: 1.08e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1622918265 456 RIGHCMLFHskNRCLYVFGGQRSKTYLNDFFSYDVDSD 493
Cdd:pfam01344 2 RSGAGVVVV--GGKIYVIGGFDGNQSLNSVEVYDPETN 37
|
|
| Kelch |
smart00612 |
Kelch domain; |
285-311 |
1.30e-03 |
|
Kelch domain;
Pssm-ID: 128874 [Multi-domain] Cd Length: 47 Bit Score: 37.15 E-value: 1.30e-03
|
| LisH |
smart00667 |
Lissencephaly type-1-like homology motif; Alpha-helical motif present in Lis1, treacle, ... |
172-202 |
8.64e-03 |
|
Lissencephaly type-1-like homology motif; Alpha-helical motif present in Lis1, treacle, Nopp140, some katanin p60 subunits, muskelin, tonneau, LEUNIG and numerous WD40 repeat-containing proteins. It is suggested that LisH motifs contribute to the regulation of microtubule dynamics, either by mediating dimerisation, or else by binding cytoplasmic dynein heavy chain or microtubules directly.
Pssm-ID: 128913 Cd Length: 34 Bit Score: 34.33 E-value: 8.64e-03
10 20 30
....*....|....*....|....*....|.
gi 1622918265 172 REQEAIRLCLKHFRQHNYTEAFESLQKKTKI 202
Cdd:smart00667 2 SRSELNRLILEYLLRNGYEETAETLQKESGL 32
|
|
| |
