|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
673-898 |
4.83e-64 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
:
Pssm-ID: 397130 Cd Length: 203 Bit Score: 216.46 E-value: 4.83e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 673 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 752
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 753 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 832
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622905303 833 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLR 898
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELR 200
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1350-1482 |
2.85e-57 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
:
Pssm-ID: 211397 Cd Length: 134 Bit Score: 194.04 E-value: 2.85e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1350 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC- 1428
Cdd:cd11559 1 LPLLRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDd 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1622905303 1429 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1482
Cdd:cd11559 81 DEQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1154-1266 |
6.90e-37 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
:
Pssm-ID: 397128 Cd Length: 113 Bit Score: 135.10 E-value: 6.90e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1154 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1233
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1622905303 1234 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1266
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
4-482 |
2.43e-06 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 2.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 4 PSQISYPASQGAYYIPGQGRStyvvPTQQYPVQPG--APGFYPGASPTEfgtyagAYYP-----AQGVQQFPTGVA--PA 74
Cdd:PHA03247 2483 PAEARFPFAAGAAPDPGGGGP----PDPDAPPAPSrlAPAILPDEPVGE------PVHPrmltwIRGLEELASDDAgdPP 2552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 75 PVLMNQPPQIAPKRERKTIRIRdPNQGGKDITeeimsgARTASTPTPPQTGGGLEPQANGETPQVAVivrPDDRSQGAII 154
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPA-PRPSEPAVT------SRARRPDAPPQSARPRAPVDDRGDPRGPA---PPSPLPPDTH 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 155 ADRPGLPGPEHSPSESQPSSPSPTPSPSpvlEPGSEPNLAVLSIPGDTMATIQMSVEESTP------ISRETGEPYRLS- 227
Cdd:PHA03247 2623 APDPPPPSPSPAANEPDPHPPPTVPPPE---RPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrrAARPTVGSLTSLa 2699
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 228 ----PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQASTPLASHTveihePNGMV----PSEDLEPEVESSPELALPPAC 299
Cdd:PHA03247 2700 dpppPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV-----PAGPAtpggPARPARPPTTAGPPAPAPPAA 2774
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 300 PSESP---VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEvTASVAPATILSATPAMAPSATSPAqeeemeeeEEE 376
Cdd:PHA03247 2775 PAAGPprrLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL-PPAASPAGPLPPPTSAQPTAPPPP--------PGP 2845
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 377 EEEGEAGEAESEKGGE--ELLPSESTPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEavgdlLDAFKEANPAVPE 454
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPER-----PPQPQAPPPPQPQ 2920
|
490 500
....*....|....*....|....*...
gi 1622905303 455 VENQPPAGSNPGPESEGSGVPPRPEEAD 482
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPRPQPPLAPTTD 2948
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
673-898 |
4.83e-64 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 216.46 E-value: 4.83e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 673 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 752
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 753 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 832
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622905303 833 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLR 898
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELR 200
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1350-1482 |
2.85e-57 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 194.04 E-value: 2.85e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1350 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC- 1428
Cdd:cd11559 1 LPLLRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDd 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1622905303 1429 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1482
Cdd:cd11559 81 DEQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
674-901 |
1.68e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 186.03 E-value: 1.68e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 674 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 753
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 754 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 833
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622905303 834 KLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRGSN 901
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1154-1266 |
6.90e-37 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 135.10 E-value: 6.90e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1154 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1233
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1622905303 1234 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1266
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1154-1266 |
8.13e-36 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 131.98 E-value: 8.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1154 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1233
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1622905303 1234 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1266
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1421-1504 |
1.84e-26 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 104.29 E-value: 1.84e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1421 KLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFKW 1500
Cdd:smart00515 2 PLLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTW 79
|
....
gi 1622905303 1501 LREA 1504
Cdd:smart00515 80 LQEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1433-1509 |
3.47e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 94.52 E-value: 3.47e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622905303 1433 ELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFKWLREAEEESD 1509
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-482 |
2.43e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 2.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 4 PSQISYPASQGAYYIPGQGRStyvvPTQQYPVQPG--APGFYPGASPTEfgtyagAYYP-----AQGVQQFPTGVA--PA 74
Cdd:PHA03247 2483 PAEARFPFAAGAAPDPGGGGP----PDPDAPPAPSrlAPAILPDEPVGE------PVHPrmltwIRGLEELASDDAgdPP 2552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 75 PVLMNQPPQIAPKRERKTIRIRdPNQGGKDITeeimsgARTASTPTPPQTGGGLEPQANGETPQVAVivrPDDRSQGAII 154
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPA-PRPSEPAVT------SRARRPDAPPQSARPRAPVDDRGDPRGPA---PPSPLPPDTH 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 155 ADRPGLPGPEHSPSESQPSSPSPTPSPSpvlEPGSEPNLAVLSIPGDTMATIQMSVEESTP------ISRETGEPYRLS- 227
Cdd:PHA03247 2623 APDPPPPSPSPAANEPDPHPPPTVPPPE---RPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrrAARPTVGSLTSLa 2699
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 228 ----PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQASTPLASHTveihePNGMV----PSEDLEPEVESSPELALPPAC 299
Cdd:PHA03247 2700 dpppPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV-----PAGPAtpggPARPARPPTTAGPPAPAPPAA 2774
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 300 PSESP---VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEvTASVAPATILSATPAMAPSATSPAqeeemeeeEEE 376
Cdd:PHA03247 2775 PAAGPprrLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL-PPAASPAGPLPPPTSAQPTAPPPP--------PGP 2845
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 377 EEEGEAGEAESEKGGE--ELLPSESTPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEavgdlLDAFKEANPAVPE 454
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPER-----PPQPQAPPPPQPQ 2920
|
490 500
....*....|....*....|....*...
gi 1622905303 455 VENQPPAGSNPGPESEGSGVPPRPEEAD 482
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPRPQPPLAPTTD 2948
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
53-364 |
8.45e-04 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 43.80 E-value: 8.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 53 TYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDiTEEIMSGARTA--STPTPPQTGGGLEP 130
Cdd:pfam17823 116 AAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASA-PHAASPAPRTAasSTTAASSTTAASSA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 131 QANGETPQVAVIVRPDDRSQGAIIADRPGLpGPEHSPSESQPSSPSPTPSPSPVLEPGSepnLAVLSIPGDTMATIQMSV 210
Cdd:pfam17823 195 PTTAASSAPATLTPARGISTAATATGHPAA-GTALAAVGNSSPAAGTVTAAVGTVTPAA---LATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 211 EESTPISRetgepyRLSPeptplaepilevevtlSKPVPESEFSSSPLQASTPLASHTVeihepngMVPSEDlEPEVESS 290
Cdd:pfam17823 271 NMGDPHAR------RLSP----------------AKHMPSDTMARNPAAPMGAQAQGPI-------IQVSTD-QPVHNTA 320
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622905303 291 PElalppacpsESPVPIAPTAQPeellNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMapSATSP 364
Cdd:pfam17823 321 GE---------PTPSPSNTTLEP----NTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEV--EATSP 379
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MIF4G |
pfam02854 |
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). ... |
673-898 |
4.83e-64 |
|
MIF4G domain; MIF4G is named after Middle domain of eukaryotic initiation factor 4G (eIF4G). Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA.
Pssm-ID: 397130 Cd Length: 203 Bit Score: 216.46 E-value: 4.83e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 673 FRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlkvpttekpTVTVNFR 752
Cdd:pfam02854 1 LKKVKGILNKLSPENFEKLIKELLKLIMSDPELLKYLIELIFEKAVEEPNFIPAYARLCSGLNL---------RNPTDFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 753 KLLLNRCQKEFEKdkdddevfekkqkemdeaataeergrlKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCV 832
Cdd:pfam02854 72 IHLLNRLQEEFEK---------------------------RFELEENEQGNRRRRLGLVRFLGELYKFGLLTEKILFECL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622905303 833 VKLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKII---KEKKTSSRIRFMLQDVLDLR 898
Cdd:pfam02854 125 KELLSSLtkedlkrDLFNLECLLTLLTTIGKLLENEKLPKLMDQFLDEIQKYVlskDDPKLSSRLRFMLQDLIELR 200
|
|
| W2_eIF4G1_like |
cd11559 |
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar ... |
1350-1482 |
2.85e-57 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; eIF4G1 is a component of the multi-subunit eukaryotic translation initiation factor 4F, which facilitates recruitment of the mRNA to the ribosome, a rate-limiting step during translation initiation. This C-terminal domain, whose structure resembles that of a set of concatenated HEAT repeats, has been associated with binding to/recruiting the kinase Mnk1, which phosphorylates eIF4E.
Pssm-ID: 211397 Cd Length: 134 Bit Score: 194.04 E-value: 2.85e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1350 LPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC- 1428
Cdd:cd11559 1 LPLLRVQAELLKLLQEDPNPDELYKWIKENVSPELYASPGFVRALMTAVLKYAIEEKSLPEKEKALLEKYAPLLQKYLDd 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1622905303 1429 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPA 1482
Cdd:cd11559 81 DEQLQLQALYALQALVHTLEFPKGLLLRFFDALYDEDVIEEEAFLKWKEDVDPA 134
|
|
| MIF4G |
smart00543 |
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The ... |
674-901 |
1.68e-53 |
|
Middle domain of eukaryotic initiation factor 4G (eIF4G); Also occurs in NMD2p and CBP80. The domain is rich in alpha-helices and may contain multiple alpha-helical repeats. In eIF4G, this domain binds eIF4A, eIF3, RNA and DNA. Ponting (TiBS) "Novel eIF4G domain homologues (in press)
Pssm-ID: 214713 Cd Length: 200 Bit Score: 186.03 E-value: 1.68e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 674 RRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAlKVPttekptvtvNFRK 753
Cdd:smart00543 2 KKVKGLINKLSPSNFESIIKELLKLNNSDKNLRKYILELIFEKAVEEPNFIPAYARLCALLNA-KNP---------DFGS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 754 LLLNRCQKEFEKDkdddevfekkqkemdeaataeergrlkeeLEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVV 833
Cdd:smart00543 72 LLLERLQEEFEKG-----------------------------LESEEESDKQRRLGLVRFLGELYNFQVLTSKIILELLK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622905303 834 KLLKNH-------DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKT---SSRIRFMLQDVLDLRGSN 901
Cdd:smart00543 123 ELLNDLtkldpprSDFSVECLLSLLPTCGKDLEREKSPKLLDEILERLQDYLLKKDKtelSSRLRFMLELLIELRKNK 200
|
|
| MA3 |
pfam02847 |
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain ... |
1154-1266 |
6.90e-37 |
|
MA3 domain; Domain in DAP-5, eIF4G, MA-3 and other proteins. Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains.
Pssm-ID: 397128 Cd Length: 113 Bit Score: 135.10 E-value: 6.90e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1154 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1233
Cdd:pfam02847 1 LKRKIFLILEEYLSSGDYDEAARCLLKLGLPSQHHEVVKVLIECALEESKTYREFYGLLLERLCEFNLISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1622905303 1234 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1266
Cdd:pfam02847 81 VLEDLEDLELDIPNAWRNLAEFVARLISDDGLP 113
|
|
| MA3 |
smart00544 |
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and ... |
1154-1266 |
8.13e-36 |
|
Domain in DAP-5, eIF4G, MA-3 and other proteins; Highly alpha-helical. May contain repeats and/or regions similar to MIF4G domains Ponting (TIBS) "Novel eIF4G domain homologues" in press
Pssm-ID: 214714 Cd Length: 113 Bit Score: 131.98 E-value: 8.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1154 LEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYE 1233
Cdd:smart00544 1 LKKKIFLIIEEYLSSGDTDEAVHCLLELKLPEQHHEVVKVLLTCALEEKRTYREMYSVLLSRLCQANVISTKQFEKGFWR 80
|
90 100 110
....*....|....*....|....*....|...
gi 1622905303 1234 ILELAEDMEIDIPHVWLYLAELVTPILQEGGVP 1266
Cdd:smart00544 81 LLEDIEDLELDIPNAWRNLAEFVARLISDGILP 113
|
|
| eIF5C |
smart00515 |
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
1421-1504 |
1.84e-26 |
|
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5;
Pssm-ID: 214705 Cd Length: 83 Bit Score: 104.29 E-value: 1.84e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1421 KLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqqGKGVALKSVTAFFKW 1500
Cdd:smart00515 2 PLLKFLAKDEEEQLELLYAIEEFCVELEKLGKLLPKILKSLYDADILEEEAILKWYEKAVSAE--GKKKVRKNAKPFVTW 79
|
....
gi 1622905303 1501 LREA 1504
Cdd:smart00515 80 LQEA 83
|
|
| W2 |
pfam02020 |
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
1433-1509 |
3.47e-23 |
|
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors.
Pssm-ID: 460415 Cd Length: 76 Bit Score: 94.52 E-value: 3.47e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622905303 1433 ELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEqQGKGVALKSVTAFFKWLREAEEESD 1509
Cdd:pfam02020 1 QVDLLLALQEFCAKLEELLKLLLKILKALYDLDIVEEEAILKWWEDVSSAE-KGMKKVRKQAKPFVEWLEEAEEESD 76
|
|
| W2 |
cd11473 |
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
1351-1476 |
3.64e-23 |
|
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211395 Cd Length: 135 Bit Score: 96.78 E-value: 3.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1351 PSEELNRQLEKLLKEG-SSNQRVFDWIEANLSEQQIASNTLVRALMTAVCYSAIIFE----TPLRVDVAVLKARAKLLQK 1425
Cdd:cd11473 2 KNKKLRDSLLKELEEDkSSDVESVKAAKSKLDLDPISLEEVVKVLLTAVVNAVESADsislTQKEQLVLVLKKYGPVLRE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1622905303 1426 YLCD-EQKELQALYALQALVVT--LEQPPNLLRMFFDALYDEDVVKEDAFYSWE 1476
Cdd:cd11473 82 LLKLiKKDQLYLLLKIEKLCLQlkLSELISLLEKILDLLYDADVLSEEAILSWF 135
|
|
| W2_eIF2B_epsilon |
cd11558 |
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a ... |
1379-1509 |
2.48e-15 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a heteropentameric complex which functions as a guanine nucleotide exchange factor in the recycling of eIF-2 during the initiation of translation in eukaryotes. The epsilon and gamma subunits are sequence similar and both are essential in yeast. Epsilon appears to be the catalytically active subunit, with gamma enhancing its activity. The C-terminal domain of the eIF2B epsilon subunit contains bipartite motifs rich in acidic and aromatic residues, which are responsible for the interaction with eIF2. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211396 Cd Length: 169 Bit Score: 75.37 E-value: 2.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1379 NLSEQQIASNTlVRALMTAVCYSAIIFETPLRVDVAVLKARAK-LLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMF 1457
Cdd:cd11558 39 NVTDHDVRRAV-VKALLELILEVSSTSTAELLEALKKLLSKWGpLLENYVKSQDDQVELLLALEEFCLESEEGGPLFAKL 117
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1622905303 1458 FDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 1509
Cdd:cd11558 118 LHALYDLDILEEEAILEWWEEPDAGADEEMKKVRELVKKFIEWLEEAEEESD 169
|
|
| W2_eIF5 |
cd11561 |
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
1358-1509 |
4.26e-09 |
|
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211399 Cd Length: 157 Bit Score: 56.86 E-value: 4.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1358 QLEKLLKEGSSNQRVFDwIEANLSEQQIASNTLVRALmtavcysAIIFETPLRVD-VAVLKARAKLLQKYLCDEQKELQA 1436
Cdd:cd11561 10 ELGEFLKKNKDESGLSE-LKEILKEAERLDVVKDKAV-------LVLAEVLFDENiVKEIKKRKALLLKLVTDEKAQKAL 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622905303 1437 LYALQALVVtlEQPPNLLRMF---FDALYDEDVVKEDAFYSW---ESSKDPAEQQGKGVaLKSVTAFFKWLREAEEESD 1509
Cdd:cd11561 82 LGGIERFCG--KHSPELLKKVpliLKALYDNDILEEEVILKWyekVSKKYVSKEKSKKV-RKAAEPFVEWLEEAEEEEE 157
|
|
| W2_eIF5C_like |
cd11560 |
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
1347-1507 |
9.16e-08 |
|
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats.
Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 54.14 E-value: 9.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1347 QRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIASN--------TLVRALMTAVCYSA---IIFETPLRVdvav 1415
Cdd:cd11560 29 YRKQASQEIKKELQQELKEMIAEEEPVKEIIAAVKEQMKKSSlpehevvgLLWTALMDAVEWSKkedQIAEQALRH---- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 1416 LKARAKLLQKYLCDEQKELQALYALQalVVTLEQPpNLLRMFFD---ALYDEDVVKEDAFYSWesSKDPAEQQGKGVALK 1492
Cdd:cd11560 105 LKKYAPLLAAFCTTARAELALLNKIQ--EYCYENM-KFMKVFQKivkLLYKADVLSEDAILKW--YKKGHSPKGKQVFLK 179
|
170
....*....|....*
gi 1622905303 1493 SVTAFFKWLREAEEE 1507
Cdd:cd11560 180 QMEPFVEWLQEAEEE 194
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-482 |
2.43e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 2.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 4 PSQISYPASQGAYYIPGQGRStyvvPTQQYPVQPG--APGFYPGASPTEfgtyagAYYP-----AQGVQQFPTGVA--PA 74
Cdd:PHA03247 2483 PAEARFPFAAGAAPDPGGGGP----PDPDAPPAPSrlAPAILPDEPVGE------PVHPrmltwIRGLEELASDDAgdPP 2552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 75 PVLMNQPPQIAPKRERKTIRIRdPNQGGKDITeeimsgARTASTPTPPQTGGGLEPQANGETPQVAVivrPDDRSQGAII 154
Cdd:PHA03247 2553 PPLPPAAPPAAPDRSVPPPRPA-PRPSEPAVT------SRARRPDAPPQSARPRAPVDDRGDPRGPA---PPSPLPPDTH 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 155 ADRPGLPGPEHSPSESQPSSPSPTPSPSpvlEPGSEPNLAVLSIPGDTMATIQMSVEESTP------ISRETGEPYRLS- 227
Cdd:PHA03247 2623 APDPPPPSPSPAANEPDPHPPPTVPPPE---RPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrrAARPTVGSLTSLa 2699
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 228 ----PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQASTPLASHTveihePNGMV----PSEDLEPEVESSPELALPPAC 299
Cdd:PHA03247 2700 dpppPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAV-----PAGPAtpggPARPARPPTTAGPPAPAPPAA 2774
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 300 PSESP---VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEvTASVAPATILSATPAMAPSATSPAqeeemeeeEEE 376
Cdd:PHA03247 2775 PAAGPprrLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL-PPAASPAGPLPPPTSAQPTAPPPP--------PGP 2845
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 377 EEEGEAGEAESEKGGE--ELLPSESTPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEavgdlLDAFKEANPAVPE 454
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPER-----PPQPQAPPPPQPQ 2920
|
490 500
....*....|....*....|....*...
gi 1622905303 455 VENQPPAGSNPGPESEGSGVPPRPEEAD 482
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPRPQPPLAPTTD 2948
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
189-475 |
7.50e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 50.62 E-value: 7.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 189 SEPNLAVLSIPGDTMATIQMSVEE------STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAST 262
Cdd:PRK07003 336 GELGLAPDEYAGFTMTLLRMLAFEpavtggGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 263 PLASHTVEIHEPNGMVPSEDLEPEVESSPElalPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVS--------EP 334
Cdd:PRK07003 416 AAAAATRAEAPPAAPAPPATADRGDDAADG---DAPVPAKANARASADSRCDERDAQPPADSGSASAPASdappdaafEP 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 335 EEQAKEVTASVAPATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEELL----------------PSE 398
Cdd:PRK07003 493 APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALdvlrnagmrvssdrgaRAA 572
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622905303 399 STPVPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVP 475
Cdd:PRK07003 573 AAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDIPPDDYVPLSADEGFGGP 649
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
10-476 |
7.25e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 47.63 E-value: 7.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 10 PASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQ--FPTGVAPAPVLMNQPPQIAPK 87
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRraARPTVGSLTSLADPPPPPPTP 2708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 88 RERktirirdPNQGGKDITEEIMSGARTASTPTPPQTGGglePQANGETPQVAVIVRPDDRSQGAIIADRPGLP----GP 163
Cdd:PHA03247 2709 EPA-------PHALVSATPLPPGPAAARQASPALPAAPA---PPAVPAGPATPGGPARPARPPTTAGPPAPAPPaapaAG 2778
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 164 EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPYRLSPEPTPLAEPilevevT 243
Cdd:PHA03247 2779 PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP------L 2852
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 244 LSKPVPESEFSSSPLQASTPlASHTVEIHEPNGMVPSEDLEPEVESSPELALPPACPSESPVPIAPTAQPEELLNGAPSP 323
Cdd:PHA03247 2853 GGSVAPGGDVRRRPPSRSPA-AKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 324 -------PAVDLSPVSEPEEQAKEVTASVAP---ATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEE 393
Cdd:PHA03247 2932 pppppprPQPPLAPTTDPAGAGEPSGAVPQPwlgALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSL 3011
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 394 LLPSESTPVPANLSQNL------EAAAATQVAVSVPKRrrkikelNKKEAVgDLLDAFKEANPAVPEVENQPPAGSNPGP 467
Cdd:PHA03247 3012 ALHEETDPPPVSLKQTLwppddtEDSDADSLFDSDSER-------SDLEAL-DPLPPEPHDPFAHEPDPATPEAGARESP 3083
|
....*....
gi 1622905303 468 ESEgSGVPP 476
Cdd:PHA03247 3084 SSQ-FGPPP 3091
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
28-487 |
1.10e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 47.24 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 28 VPTQQYPVQPGAPGF-----YPGASPTEfgtyAGAYYPAQGVQQFPTGVAPAPVlmnqPPQIAPKRERKTIRIRDPNQGG 102
Cdd:PHA03247 2568 VPPPRPAPRPSEPAVtsrarRPDAPPQS----ARPRAPVDDRGDPRGPAPPSPL----PPDTHAPDPPPPSPSPAANEPD 2639
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 103 KDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV-AVIVRPDDRSQGAIIAD-----RPGLPGPEhSPSESQPSSPS 176
Cdd:PHA03247 2640 PHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQAsSPPQRPRRRAARPTVGSltslaDPPPPPPT-PEPAPHALVSA 2718
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 177 PTPSPSPVLEPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPyrlSPEPTPLAEPILEVEVTLSKPVPESEFSSS 256
Cdd:PHA03247 2719 TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAG---PPAPAPPAAPAAGPPRRLTRPAVASLSESR 2795
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 257 PLQASTP-LASHTVEIHEPNGMVPSEDlEPEVESSPELALPPACPSESPVPIAPTAQPeellnGAPSPPAVDLSPVSEPE 335
Cdd:PHA03247 2796 ESLPSPWdPADPPAAVLAPAAALPPAA-SPAGPLPPPTSAQPTAPPPPPGPPPPSLPL-----GGSVAPGGDVRRRPPSR 2869
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 336 EQAKEVTASVAPATILSATPAMAPSATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEEL-LPSESTPV--PANLSQNLEA 412
Cdd:PHA03247 2870 SPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQpQPPPPPPPrpQPPLAPTTDP 2949
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622905303 413 AAATQVAVSVPKRRrkikelnkkeavgdlLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDS 487
Cdd:PHA03247 2950 AGAGEPSGAVPQPW---------------LGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWAS 3009
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
213-366 |
6.63e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 44.26 E-value: 6.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 213 STPISR-ETGEPYRLSPEPTPLAEPILeVEVTLSKPVPESEfSSSPLQASTPLASHTVEIHEPN--GMVPSEDLEPEVES 289
Cdd:PRK10811 844 RYPVVRpQDVQVEEQREAEEVQVQPVV-AEVPVAAAVEPVV-SAPVVEAVAEVVEEPVVVAEPQpeEVVVVETTHPEVIA 921
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 290 SPELALPP-------ACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMAPSAT 362
Cdd:PRK10811 922 APVTEQPQvitesdvAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEV 1001
|
....
gi 1622905303 363 SPAQ 366
Cdd:PRK10811 1002 APAQ 1005
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
318-484 |
7.19e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.10 E-value: 7.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 318 NGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMAPS----ATSPAQEEEMEEEEEEEEEGEAGEAESEKGGEE 393
Cdd:PRK12323 369 GGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAaaaaARAVAAAPARRSPAPEALAAARQASARGPGGAP 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 394 LLPSESTPVPANLSQNLEAAAATQVAVSVPKRRRKIKElNKKEAVGDLLDAFKEANPAVPEVenqPPAGSNPGPESEGSG 473
Cdd:PRK12323 449 APAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPA-AAPAPADDDPPPWEELPPEFASP---APAQPDAAPAGWVAE 524
|
170
....*....|.
gi 1622905303 474 VPPRPEEADET 484
Cdd:PRK12323 525 SIPDPATADPD 535
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
53-364 |
8.45e-04 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 43.80 E-value: 8.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 53 TYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDiTEEIMSGARTA--STPTPPQTGGGLEP 130
Cdd:pfam17823 116 AAAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAAASA-PHAASPAPRTAasSTTAASSTTAASSA 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 131 QANGETPQVAVIVRPDDRSQGAIIADRPGLpGPEHSPSESQPSSPSPTPSPSPVLEPGSepnLAVLSIPGDTMATIQMSV 210
Cdd:pfam17823 195 PTTAASSAPATLTPARGISTAATATGHPAA-GTALAAVGNSSPAAGTVTAAVGTVTPAA---LATLAAAAGTVASAAGTI 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 211 EESTPISRetgepyRLSPeptplaepilevevtlSKPVPESEFSSSPLQASTPLASHTVeihepngMVPSEDlEPEVESS 290
Cdd:pfam17823 271 NMGDPHAR------RLSP----------------AKHMPSDTMARNPAAPMGAQAQGPI-------IQVSTD-QPVHNTA 320
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622905303 291 PElalppacpsESPVPIAPTAQPeellNGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPAMapSATSP 364
Cdd:pfam17823 321 GE---------PTPSPSNTTLEP----NTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEV--EATSP 379
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
97-361 |
1.49e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.54 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 97 DPNQGGKDITEEIMSGARTAS------------TPTPPQTGgglePQANGETPQVAVIVRPDDRSQGAIIADRP------ 158
Cdd:PRK10263 308 DPLLNGAPITEPVAVAAAATTatqswaapvepvTQTPPVAS----VDVPPAQPTVAWQPVPGPQTGEPVIAPAPegypqq 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 159 ---GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMATIQMSVEESTPISRETGEPyrlsPEPTPLAE 235
Cdd:PRK10263 384 sqyAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEE----QQSTFAPQ 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 236 PILEVEVTLSKPVPESEFSSSPLQASTPLASHTV-EIHEPNGMVPSEDLEPEVESS-----PELAL---PPACPSESPVP 306
Cdd:PRK10263 460 STYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEpVVEETKPARPPLYYFEEVEEKrarerEQLAAwyqPIPEPVKEPEP 539
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1622905303 307 IAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAkevtASVAPATILSATPAMAPSA 361
Cdd:PRK10263 540 IKSSLKAPSVAAVPPVEAAAAVSPLASGVKKA----TLATGAAATVAAPVFSLAN 590
|
|
| TALPID3 |
pfam15324 |
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ... |
200-335 |
3.10e-03 |
|
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.
Pssm-ID: 434634 [Multi-domain] Cd Length: 1288 Bit Score: 42.18 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 200 GDTMATIQMSVEESTPISRETGEPYRLSPEPTPLAEPilevevTLSKPVPESEfsssPLQASTPLASHTVEIHEpngMVP 279
Cdd:pfam15324 959 GDREAQREPPVAASVPGDLPTKETLLPTPVPTPQPTP------PCSPPSPLKE----PSPVKTPDSSPCVSEHD---FFP 1025
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622905303 280 SEDLEPEVESSPELALPPA-CPSESPVPIAPTAqpeellnGAPSPP----AVDLSPVSEPE 335
Cdd:pfam15324 1026 VKEIPPEKGADTGPAVSLViTPTVTPIATPPPA-------ATPTPPlsenSIDKLKSPSPE 1079
|
|
| PHA03325 |
PHA03325 |
nuclear-egress-membrane-like protein; Provisional |
204-364 |
5.06e-03 |
|
nuclear-egress-membrane-like protein; Provisional
Pssm-ID: 223044 Cd Length: 418 Bit Score: 41.02 E-value: 5.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 204 ATIQMSVEESTPISRETG-EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQASTplashtveihepnGMVPSED 282
Cdd:PHA03325 262 FMLNSSLPTSAPKRRSRRaGAMRAAAGETADLADDDGSEHSDPEPLPASLPPPPVRRPRV-------------KHPEAGK 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622905303 283 LEPEVESSPElALPPACPSESP-VPIAPTAQPEEllnGAPSPPAVDLSPVSEPEEQAKEVTASVAPATILSATPaMAPSA 361
Cdd:PHA03325 329 EEPDGARNAE-AKEPAQPATSTsSKGSSSAQNKD---SGSTGPGSSLAAASSFLEDDDFGSPPLDLTTSLRHMP-SPSVT 403
|
...
gi 1622905303 362 TSP 364
Cdd:PHA03325 404 SAP 406
|
|
| |
