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Conserved domains on  [gi|1622904486|ref|XP_028699637|]
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leucine-, glutamate- and lysine-rich protein 1 isoform X1 [Macaca mulatta]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 321-595 3.28e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 3.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 321 YRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELM---LISHQKSIEQLQETL-RQKLLSDD 396
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAqaeEYELLAELARLEQDIaRLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 397 NWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALR 476
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 477 EKLHEshiryteeseskekeiENLKNLVAEFESRLKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEE 556
Cdd:COG1196   394 AAAEL----------------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1622904486 557 NTFLQETVRRECEERFELTEALSQAREQLLELRKLRGSL 595
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
Mplasa_alph_rch super family cl37461
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 35-588 3.96e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


The actual alignment was detected with superfamily member TIGR04523:

Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 3.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  35 HEFKAMEEKVKAMEKEMKFYQGSV-DREKRLQEKLHSLNQELEQYKIDSKskteRIYDVGMQLKNQQNEFQKVEKQLSHL 113
Cdd:TIGR04523  33 TEEKQLEKKLKTIKNELKNKEKELkNLDKNLNKDEEKINNSNNKIKILEQ----QIKDLNDKLKKNKDKINKLNSDLSKI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 114 QDELKIKYRQSYIFSQRLSEYKYFWNKTLSLLTFTKRELTSIKNEVYDNYQNWTSLKGEIflqiksisETALTEIDILNK 193
Cdd:TIGR04523 109 NSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK--------EELENELNLLEK 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 194 slivsqrNKVCLEKEMKNLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKE 273
Cdd:TIGR04523 181 -------EKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 274 MLMNKSNEADDCQRELRKLKFESVisesQHTMLLKEKEDSLMTCQQIYRAL----QEELTAKEKQE-EDIKRRINLAENE 348
Cdd:TIGR04523 254 QLNQLKDEQNKIKKQLSEKQKELE----QNNKKIKELEKQLNQLKSEISDLnnqkEQDWNKELKSElKNQEKKLEEIQNQ 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 349 LEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQ-KLLSDDNWKEKIEAELAKERAQHLvefeEQALLFKEE 427
Cdd:TIGR04523 330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEiEKLKKENQSYKQEIKNLESQINDL----ESKIQNQEK 405

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 428 TKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLitgatrdlRQEVTALREKLHESHIRYTEESESKEKEIENLKNLvaef 507
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--------NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL---- 473

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 508 esrlKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRRECEERFELTEALSQAREQLLE 587
Cdd:TIGR04523 474 ----SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549


                  .
gi 1622904486 588 L 588
Cdd:TIGR04523 550 D 550
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 321-595 3.28e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 3.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 321 YRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELM---LISHQKSIEQLQETL-RQKLLSDD 396
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAqaeEYELLAELARLEQDIaRLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 397 NWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALR 476
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 477 EKLHEshiryteeseskekeiENLKNLVAEFESRLKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEE 556
Cdd:COG1196   394 AAAEL----------------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1622904486 557 NTFLQETVRRECEERFELTEALSQAREQLLELRKLRGSL 595
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 338-589 6.19e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 6.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  338 IKRRINLAENELEITKT--LLNQTREEVLTLKNERELMlishQKSIEQLQETLRQKLLSDDNWKEKIEAELAK-ERAQHL 414
Cdd:TIGR02168  673 LERRREIEELEEKIEELeeKIAELEKALAELRKELEEL----EEELEQLRKELEELSRQISALRKDLARLEAEvEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  415 VEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDL------ITGATRDLRQEVTALREKLHESHIRYTE 488
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkaLREALDELRAELTLLNEEAANLRERLES 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  489 ESESKEKEIENLKNLVAEFEsRLKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRREC 568
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIE-ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          250       260
                   ....*....|....*....|.
gi 1622904486  569 EERFELTEALSQAREQLLELR 589
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLE 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 35-588 3.96e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 3.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  35 HEFKAMEEKVKAMEKEMKFYQGSV-DREKRLQEKLHSLNQELEQYKIDSKskteRIYDVGMQLKNQQNEFQKVEKQLSHL 113
Cdd:TIGR04523  33 TEEKQLEKKLKTIKNELKNKEKELkNLDKNLNKDEEKINNSNNKIKILEQ----QIKDLNDKLKKNKDKINKLNSDLSKI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 114 QDELKIKYRQSYIFSQRLSEYKYFWNKTLSLLTFTKRELTSIKNEVYDNYQNWTSLKGEIflqiksisETALTEIDILNK 193
Cdd:TIGR04523 109 NSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK--------EELENELNLLEK 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 194 slivsqrNKVCLEKEMKNLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKE 273
Cdd:TIGR04523 181 -------EKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 274 MLMNKSNEADDCQRELRKLKFESVisesQHTMLLKEKEDSLMTCQQIYRAL----QEELTAKEKQE-EDIKRRINLAENE 348
Cdd:TIGR04523 254 QLNQLKDEQNKIKKQLSEKQKELE----QNNKKIKELEKQLNQLKSEISDLnnqkEQDWNKELKSElKNQEKKLEEIQNQ 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 349 LEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQ-KLLSDDNWKEKIEAELAKERAQHLvefeEQALLFKEE 427
Cdd:TIGR04523 330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEiEKLKKENQSYKQEIKNLESQINDL----ESKIQNQEK 405

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 428 TKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLitgatrdlRQEVTALREKLHESHIRYTEESESKEKEIENLKNLvaef 507
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--------NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL---- 473

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 508 esrlKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRRECEERFELTEALSQAREQLLE 587
Cdd:TIGR04523 474 ----SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549


                  .
gi 1622904486 588 L 588
Cdd:TIGR04523 550 D 550
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 185-459 7.18e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.27  E-value: 7.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 185 LTEIDILNKSLIVSQRNKVCLEkemknlkllsdaailRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVK---L 261
Cdd:pfam17380 265 MTENEFLNQLLHIVQHQKAVSE---------------RQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARqaeM 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 262 QKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISE--SQHTMLLKEKEDSLMTCQQIYRALQEELTAKEK---QEE 336
Cdd:pfam17380 330 DRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEeiAMEISRMRELERLQMERQQKNERVRQELEAARKvkiLEE 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 337 DIKRRINLAENELEITKTLLNQTREE---VLTLKNERELMLISHQKSIEQLQ-ETLRQKllSDDNWKEKIEAElAKERAQ 412
Cdd:pfam17380 410 ERQRKIQQQKVEMEQIRAEQEEARQRevrRLEEERAREMERVRLEEQERQQQvERLRQQ--EEERKRKKLELE-KEKRDR 486

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1622904486 413 HLVEFEEQALLFKE-ETKLQLDIEKEKHQDIIQkykKEQEELQMKISD 459
Cdd:pfam17380 487 KRAEEQRRKILEKElEERKQAMIEEERKRKLLE---KEMEERQKAIYE 531
PRK12704 PRK12704
phosphodiesterase; Provisional
 329-460 6.67e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 6.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 329 TAKEKQ-EEDIKRRINLAENELE-ITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAEl 406
Cdd:PRK12704   30 EAKIKEaEEEAKRILEEAKKEAEaIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKR- 108

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1622904486 407 akeraQHLVEFEEQALLFKEEtklqlDIEKeKHQDIIQKYKKEQEELQmKISDL 460
Cdd:PRK12704  109 -----EEELEKKEKELEQKQQ-----ELEK-KEEELEELIEEQLQELE-RISGL 150
COG5022 COG5022
Myosin heavy chain [General function prediction only];
63-396 7.09e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.14  E-value: 7.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   63 RLQEKLHSLNQELEQYKidskSKTERIYDVGMQLKNQQNEFQKVEKQLSHLQDELKIKYRQSYIFSQRLSEYKY--FWNK 140
Cdd:COG5022    797 IKLQPLLSLLGSRKEYR----SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKetIYLQ 872

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  141 TLSLLTFTKRELTSIKNEVydnyqnwtslkgEIFLQIKSISETALTEIDILNKSLIVSQRNKV-CLEKEMKNLKLLSDAA 219
Cdd:COG5022    873 SAQRVELAERQLQELKIDV------------KSISSLKLVNLELESEIIELKKSLSSDLIENLeFKTELIARLKKLLNNI 940

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  220 ILRSQQI--QTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVK---LQKAVTEMDNYKEMLMNKSNEADDCQRELRKLKF 294
Cdd:COG5022    941 DLEEGPSieYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILvreGNKANSELKNFKKELAELSKQYGALQESTKQLKE 1020

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  295 ESVISesqhtmllkekeDSLMTCQQIYRALQEELtAKEKQEEDIKRRINLAEneleitktllNQTREEVLTLKNERE-LM 373
Cdd:COG5022   1021 LPVEV------------AELQSASKIISSESTEL-SILKPLQKLKGLLLLEN----------NQLQARYKALKLRREnSL 1077

                          330       340
                   ....*....|....*....|...
gi 1622904486  374 LISHQKSIEQLQETLRQKLLSDD 396
Cdd:COG5022   1078 LDDKQLYQLESTENLLKTINVKD 1100
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 34-486 1.15e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   34 LHEFKAM-EEKVKAMEKEM---------------KFYQGSVDREKRLQEKLHSLNQELEQYKIDsKSKTERIYDVGM--- 94
Cdd:pfam15921  333 LREAKRMyEDKIEELEKQLvlanseltearterdQFSQESGNLDDQLQKLLADLHKREKELSLE-KEQNKRLWDRDTgns 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   95 --------QLKNQQNEFQKVEKQLSHLQDELKIKYRQSYIFSQRLseykyfwNKTLSLLTFTKRELTSIKNEVYDNYQNW 166
Cdd:pfam15921  412 itidhlrrELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGK-------NESLEKVSSLTAQLESTKEMLRKVVEEL 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  167 TSLKGEIFLQIKSISEtalteidiLNKSLIVSQRNKVCLEKEMKNLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQE 246
Cdd:pfam15921  485 TAKKMTLESSERTVSD--------LTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQ 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  247 VLDLQCLVEALGVKLQKAVTEMDNYKE----MLMNKSN---EADDCQRELRKLKFESVISESQHTMLLKEKEDSLMTCQQ 319
Cdd:pfam15921  557 MAEKDKVIEILRQQIENMTQLVGQHGRtagaMQVEKAQlekEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVK 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  320 IYRALQEELTAKE--KQEED--------IKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLR 389
Cdd:pfam15921  637 LVNAGSERLRAVKdiKQERDqllnevktSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLK 716

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  390 QKLLSDDN-------WKEKIEAELAKERA-QHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKIsDLI 461
Cdd:pfam15921  717 SMEGSDGHamkvamgMQKQITAKRGQIDAlQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL-EVL 795

                          490       500
                   ....*....|....*....|....*
gi 1622904486  462 TGATRDLRQEVTALREKLHESHIRY 486
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQF 820
46 PHA02562
endonuclease subunit; Provisional
 185-440 8.83e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 39.23  E-value: 8.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 185 LTEIDILNKSLIVSqrnkvcLEKEMKNLKLLSDAAI--LRSQQIQTSRQQEVNlqtrcydlEQEVLDLQCLVEALGVKLQ 262
Cdd:PHA02562  165 LSEMDKLNKDKIRE------LNQQIQTLDMKIDHIQqqIKTYNKNIEEQRKKN--------GENIARKQNKYDELVEEAK 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 263 KAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISESQHTMLLK-----EKEDSLMTCQQiyralqeELTAKEKQEED 337
Cdd:PHA02562  231 TIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKvikmyEKGGVCPTCTQ-------QISEGPDRITK 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 338 IKRRINLAENELEitktLLNQTREEVltlkNERELMLISHQKSIEQLQ---ETLRQKLLSDDNWKEKIEAELAKERAQHL 414
Cdd:PHA02562  304 IKDKLKELQHSLE----KLDTAIDEL----EEIMDEFNEQSKKLLELKnkiSTNKQSLITLVDKAKKVKAAIEELQAEFV 375

                         250       260
                  ....*....|....*....|....*....
gi 1622904486 415 VEFEEQALLFKEETKL---QLDIEKEKHQ 440
Cdd:PHA02562  376 DNAEELAKLQDELDKIvktKSELVKEKYH 404
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 321-595 3.28e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 3.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 321 YRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELM---LISHQKSIEQLQETL-RQKLLSDD 396
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAqaeEYELLAELARLEQDIaRLEERRRE 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 397 NWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALR 476
Cdd:COG1196   314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 477 EKLHEshiryteeseskekeiENLKNLVAEFESRLKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEE 556
Cdd:COG1196   394 AAAEL----------------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1622904486 557 NTFLQETVRRECEERFELTEALSQAREQLLELRKLRGSL 595
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 338-589 6.19e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 6.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  338 IKRRINLAENELEITKT--LLNQTREEVLTLKNERELMlishQKSIEQLQETLRQKLLSDDNWKEKIEAELAK-ERAQHL 414
Cdd:TIGR02168  673 LERRREIEELEEKIEELeeKIAELEKALAELRKELEEL----EEELEQLRKELEELSRQISALRKDLARLEAEvEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  415 VEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDL------ITGATRDLRQEVTALREKLHESHIRYTE 488
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkaLREALDELRAELTLLNEEAANLRERLES 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  489 ESESKEKEIENLKNLVAEFEsRLKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRREC 568
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIE-ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907

                          250       260
                   ....*....|....*....|.
gi 1622904486  569 EERFELTEALSQAREQLLELR 589
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLE 928
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 223-587 3.59e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.99  E-value: 3.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  223 SQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISESQ 302
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  303 HTMLLKEKEdslmtcqQIYRALQEELTAKEKQEEDI---KRRINLAENELEITKTLLNQTREEVLTLKNERELM---LIS 376
Cdd:TIGR02168  763 IEELEERLE-------EAEEELAEAEAEIEELEAQIeqlKEELKALREALDELRAELTLLNEEAANLRERLESLerrIAA 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  377 HQKSIEQLQETLRQkllsddnwKEKIEAELAKERAqhlvefEEQALLFKEETKLQ-LDIEKEKHQDIIQKYKKEQEELQM 455
Cdd:TIGR02168  836 TERRLEDLEEQIEE--------LSEDIESLAAEIE------ELEELIEELESELEaLLNERASLEEALALLRSELEELSE 901

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  456 KISDLITGAtRDLRQEVTALREKLHESHIRYTEESESKEKEIENLKN---LVAEFESRLKKEIDSNDSVSEDLRKEMKQK 532
Cdd:TIGR02168  902 ELRELESKR-SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeysLTLEEAEALENKIEDDEEEARRRLKRLENK 980

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622904486  533 SDELKRVMLAQtqlIEQFNKSQEENTFLQETVrreceerfeltEALSQAREQLLE 587
Cdd:TIGR02168  981 IKELGPVNLAA---IEEYEELKERYDFLTAQK-----------EDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 182-460 1.35e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  182 ETALTEIDILNKSLIVSQRNKVCLEKEMKNLkllsdaailrSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKL 261
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQEL----------EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  262 QKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISESQHTMLLKEKEdslmtcqqiyrALQEELTAKEKQEEDIKRR 341
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-----------SLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  342 INLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAELAKERAQHLVEFEE-- 419
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEElq 453

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1622904486  420 QALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDL 460
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 35-588 3.96e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 3.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  35 HEFKAMEEKVKAMEKEMKFYQGSV-DREKRLQEKLHSLNQELEQYKIDSKskteRIYDVGMQLKNQQNEFQKVEKQLSHL 113
Cdd:TIGR04523  33 TEEKQLEKKLKTIKNELKNKEKELkNLDKNLNKDEEKINNSNNKIKILEQ----QIKDLNDKLKKNKDKINKLNSDLSKI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 114 QDELKIKYRQSYIFSQRLSEYKYFWNKTLSLLTFTKRELTSIKNEVYDNYQNWTSLKGEIflqiksisETALTEIDILNK 193
Cdd:TIGR04523 109 NSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK--------EELENELNLLEK 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 194 slivsqrNKVCLEKEMKNLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKE 273
Cdd:TIGR04523 181 -------EKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 274 MLMNKSNEADDCQRELRKLKFESVisesQHTMLLKEKEDSLMTCQQIYRAL----QEELTAKEKQE-EDIKRRINLAENE 348
Cdd:TIGR04523 254 QLNQLKDEQNKIKKQLSEKQKELE----QNNKKIKELEKQLNQLKSEISDLnnqkEQDWNKELKSElKNQEKKLEEIQNQ 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 349 LEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQ-KLLSDDNWKEKIEAELAKERAQHLvefeEQALLFKEE 427
Cdd:TIGR04523 330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEiEKLKKENQSYKQEIKNLESQINDL----ESKIQNQEK 405

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 428 TKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLitgatrdlRQEVTALREKLHESHIRYTEESESKEKEIENLKNLvaef 507
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--------NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL---- 473

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 508 esrlKKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRRECEERFELTEALSQAREQLLE 587
Cdd:TIGR04523 474 ----SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549


                  .
gi 1622904486 588 L 588
Cdd:TIGR04523 550 D 550
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 318-478 9.38e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.61  E-value: 9.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 318 QQIYRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQ-KSIEQLQETLRQKLLSDD 396
Cdd:COG1579    37 EDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKEiESLKRRISDLEDEILELM 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 397 NWKEKIEAELAKERAQHlvefeeqallfkEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALR 476
Cdd:COG1579   117 ERIEELEEELAELEAEL------------AELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPELLALYERIR 184


                  ..
gi 1622904486 477 EK 478
Cdd:COG1579   185 KR 186
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 260-477 4.19e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 4.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 260 KLQKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISESQHTML---LKEKEDSLMTCQQIYRALQEELTAKEKQEE 336
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELrleLEELELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 337 -DIKRRINLAENELEITKTL-------------LNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKI 402
Cdd:COG1196   306 rLEERRRELEERLEELEEELaeleeeleeleeeLEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622904486 403 EAELAKERAQ----HLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALRE 477
Cdd:COG1196   386 EELLEALRAAaelaAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 339-592 6.58e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 6.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 339 KRRINLAENELEITKT-------LLNQTREEVLTLKNERELmLISHQKSIEQLQETLRQKLLSDDNWKEKiEAELAKERA 411
Cdd:COG1196   171 KERKEEAERKLEATEEnlerledILGELERQLEPLERQAEK-AERYRELKEELKELEAELLLLKLRELEA-ELEELEAEL 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 412 QHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITgatrdLRQEVTALREKLHESHIRYTEESE 491
Cdd:COG1196   249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-----LEQDIARLEERRRELEERLEELEE 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 492 SKEKEIENLKNLVAEfESRLKKEIDSNDSVSEDLRKEMKQKSDELKRvmlAQTQLIEQFNKSQEENTFLQETVRRECEER 571
Cdd:COG1196   324 ELAELEEELEELEEE-LEELEEELEEAEEELEEAEAELAEAEEALLE---AEAELAEAEEELEELAEELLEALRAAAELA 399

                         250       260
                  ....*....|....*....|.
gi 1622904486 572 FELTEALSQAREQLLELRKLR 592
Cdd:COG1196   400 AQLEELEEAEEALLERLERLE 420
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 185-459 7.18e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.27  E-value: 7.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 185 LTEIDILNKSLIVSQRNKVCLEkemknlkllsdaailRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVK---L 261
Cdd:pfam17380 265 MTENEFLNQLLHIVQHQKAVSE---------------RQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARqaeM 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 262 QKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISE--SQHTMLLKEKEDSLMTCQQIYRALQEELTAKEK---QEE 336
Cdd:pfam17380 330 DRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEeiAMEISRMRELERLQMERQQKNERVRQELEAARKvkiLEE 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 337 DIKRRINLAENELEITKTLLNQTREE---VLTLKNERELMLISHQKSIEQLQ-ETLRQKllSDDNWKEKIEAElAKERAQ 412
Cdd:pfam17380 410 ERQRKIQQQKVEMEQIRAEQEEARQRevrRLEEERAREMERVRLEEQERQQQvERLRQQ--EEERKRKKLELE-KEKRDR 486

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1622904486 413 HLVEFEEQALLFKE-ETKLQLDIEKEKHQDIIQkykKEQEELQMKISD 459
Cdd:pfam17380 487 KRAEEQRRKILEKElEERKQAMIEEERKRKLLE---KEMEERQKAIYE 531
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 324-607 8.89e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 8.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  324 LQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQEtLRQKLLSDDNWKEKIE 403
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE-LEEDLSSLEQEIENVK 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  404 AELAKERAQhLVEFEEQALLFKEETKlqlDIEKEKHQDIIQKYKKEQEELQMKISDlITGATRDLRQEVTAL-------- 475
Cdd:TIGR02169  758 SELKELEAR-IEELEEDLHKLEEALN---DLEARLSHSRIPEIQAELSKLEEEVSR-IEARLREIEQKLNRLtlekeyle 832

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  476 --REKLHESHIRYTEESESKEKEIENLKNLVAEFESRLKKeidsndsvsedLRKEMKQKSDELKRVMLAQTQLIEQFNKS 553
Cdd:TIGR02169  833 keIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEE-----------LEAALRDLESRLGDLKKERDELEAQLREL 901

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622904486  554 QEENTFLQETVRRECEERFELTEALSQAREQLLELRKLRGS-LPFSPCSLSKGSL 607
Cdd:TIGR02169  902 ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdEEIPEEELSLEDV 956
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 259-546 1.03e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  259 VKLQKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISESQHTML---LKEKEDSLMTCQQIYRALQEELTAKEKQE 335
Cdd:TIGR02168  225 LELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELrleVSELEEEIEELQKELYALANEISRLEQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  336 EDIKRR--------------INLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKllsdDNWKEK 401
Cdd:TIGR02168  305 QILRERlanlerqleeleaqLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL----EELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  402 IEaELAKERAQHLvefEEQALLfkEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALREKLHE 481
Cdd:TIGR02168  381 LE-TLRSKVAQLE---LQIASL--NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622904486  482 SHIRYTEESESKEKEIENLKNLVAEFESRLkKEIDSNDSVSEDLRKEMKQKSDELKRVMLAQTQL 546
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAEREL-AQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 59-390 1.04e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   59 DREKRLQEKLHSLNQELEQYKIDSKSKTERIYDVGMQLKNQQNEFQKVEKQLSHLQDELKIKYRQSYIFSQRLSEYKYFW 138
Cdd:TIGR02169  681 ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSEL 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  139 NKTLSLLTFTKRELTSIKNEVYDNYQnwtSLKGEIFLQIKSISETALTE-------IDILNKSLIVSQRNKVCLEKEMKN 211
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEA---RLSHSRIPEIQAELSKLEEEvsriearLREIEQKLNRLTLEKEYLEKEIQE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  212 LKLLSDAAilrSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALG---VKLQKAVTEMDNYKEMLMNKSNEAD----- 283
Cdd:TIGR02169  838 LQEQRIDL---KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLEsrlGDLKKERDELEAQLRELERKIEELEaqiek 914

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  284 -DCQRELRKLKFESVISESQHTMLLKEKEDSLMTCQQIYRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREE 362
Cdd:TIGR02169  915 kRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEK 994

                          330       340
                   ....*....|....*....|....*...
gi 1622904486  363 VLTLKNERElmliSHQKSIEQLQETLRQ 390
Cdd:TIGR02169  995 RAKLEEERK----AILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 288-588 3.53e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  288 ELRKLKFESVISE--SQHTMLLKEKEDSLMtcqqiYRALQEELtakekqeedIKRRINLAENELEITKTLLNQTREEVLT 365
Cdd:TIGR02169  183 EENIERLDLIIDEkrQQLERLRREREKAER-----YQALLKEK---------REYEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  366 LknerelmlishQKSIEQLQETLRQKLLSddnwKEKIEAELAKERAQHLVEFEEQALLFKEETkLQLDIEKEKHQDIIQK 445
Cdd:TIGR02169  249 L-----------EEELEKLTEEISELEKR----LEEIEQLLEELNKKIKDLGEEEQLRVKEKI-GELEAEIASLERSIAE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  446 YKKEQEELQMKISDLITgATRDLRQEVTALREKLHESHIRYTEeseskekeienlknLVAEFESRlKKEIDSNDSVSEDL 525
Cdd:TIGR02169  313 KERELEDAEERLAKLEA-EIDKLLAEIEELEREIEEERKRRDK--------------LTEEYAEL-KEELEDLRAELEEV 376

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622904486  526 RKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRRECEERFELTEALSQAREQLLEL 588
Cdd:TIGR02169  377 DKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL 439
PRK12704 PRK12704
phosphodiesterase; Provisional
 329-460 6.67e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 6.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 329 TAKEKQ-EEDIKRRINLAENELE-ITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAEl 406
Cdd:PRK12704   30 EAKIKEaEEEAKRILEEAKKEAEaIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKR- 108

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1622904486 407 akeraQHLVEFEEQALLFKEEtklqlDIEKeKHQDIIQKYKKEQEELQmKISDL 460
Cdd:PRK12704  109 -----EEELEKKEKELEQKQQ-----ELEK-KEEELEELIEEQLQELE-RISGL 150
COG5022 COG5022
Myosin heavy chain [General function prediction only];
63-396 7.09e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.14  E-value: 7.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   63 RLQEKLHSLNQELEQYKidskSKTERIYDVGMQLKNQQNEFQKVEKQLSHLQDELKIKYRQSYIFSQRLSEYKY--FWNK 140
Cdd:COG5022    797 IKLQPLLSLLGSRKEYR----SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKetIYLQ 872

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  141 TLSLLTFTKRELTSIKNEVydnyqnwtslkgEIFLQIKSISETALTEIDILNKSLIVSQRNKV-CLEKEMKNLKLLSDAA 219
Cdd:COG5022    873 SAQRVELAERQLQELKIDV------------KSISSLKLVNLELESEIIELKKSLSSDLIENLeFKTELIARLKKLLNNI 940

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  220 ILRSQQI--QTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVK---LQKAVTEMDNYKEMLMNKSNEADDCQRELRKLKF 294
Cdd:COG5022    941 DLEEGPSieYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILvreGNKANSELKNFKKELAELSKQYGALQESTKQLKE 1020

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  295 ESVISesqhtmllkekeDSLMTCQQIYRALQEELtAKEKQEEDIKRRINLAEneleitktllNQTREEVLTLKNERE-LM 373
Cdd:COG5022   1021 LPVEV------------AELQSASKIISSESTEL-SILKPLQKLKGLLLLEN----------NQLQARYKALKLRREnSL 1077

                          330       340
                   ....*....|....*....|...
gi 1622904486  374 LISHQKSIEQLQETLRQKLLSDD 396
Cdd:COG5022   1078 LDDKQLYQLESTENLLKTINVKD 1100
PTZ00121 PTZ00121
MAEBL; Provisional
 308-584 7.63e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 7.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  308 KEKEDSLMTCQQIYRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVltlKNERELMLISHQKSIEQLQET 387
Cdd:PTZ00121  1496 KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL---KKAEELKKAEEKKKAEEAKKA 1572

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  388 LRQKLLSDDNWKEKIEAELAKeraqhlveFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLITGATRD 467
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEAR--------IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE 1644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  468 LRQEVTALREKLHESHIRYTEESESKEKEIENLKNLVAEFESRLKKEidsndsvsEDLRK--EMKQKSDELKRVMLAQTQ 545
Cdd:PTZ00121  1645 EKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAA--------EALKKeaEEAKKAEELKKKEAEEKK 1716

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1622904486  546 LIEQFNKSQEENTFLQETVRRECEERFELTEALSQAREQ 584
Cdd:PTZ00121  1717 KAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE 1755
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 34-486 1.15e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   34 LHEFKAM-EEKVKAMEKEM---------------KFYQGSVDREKRLQEKLHSLNQELEQYKIDsKSKTERIYDVGM--- 94
Cdd:pfam15921  333 LREAKRMyEDKIEELEKQLvlanseltearterdQFSQESGNLDDQLQKLLADLHKREKELSLE-KEQNKRLWDRDTgns 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   95 --------QLKNQQNEFQKVEKQLSHLQDELKIKYRQSYIFSQRLseykyfwNKTLSLLTFTKRELTSIKNEVYDNYQNW 166
Cdd:pfam15921  412 itidhlrrELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGK-------NESLEKVSSLTAQLESTKEMLRKVVEEL 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  167 TSLKGEIFLQIKSISEtalteidiLNKSLIVSQRNKVCLEKEMKNLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQE 246
Cdd:pfam15921  485 TAKKMTLESSERTVSD--------LTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQ 556

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  247 VLDLQCLVEALGVKLQKAVTEMDNYKE----MLMNKSN---EADDCQRELRKLKFESVISESQHTMLLKEKEDSLMTCQQ 319
Cdd:pfam15921  557 MAEKDKVIEILRQQIENMTQLVGQHGRtagaMQVEKAQlekEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVK 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  320 IYRALQEELTAKE--KQEED--------IKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLR 389
Cdd:pfam15921  637 LVNAGSERLRAVKdiKQERDqllnevktSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLK 716

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  390 QKLLSDDN-------WKEKIEAELAKERA-QHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKIsDLI 461
Cdd:pfam15921  717 SMEGSDGHamkvamgMQKQITAKRGQIDAlQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL-EVL 795

                          490       500
                   ....*....|....*....|....*
gi 1622904486  462 TGATRDLRQEVTALREKLHESHIRY 486
Cdd:pfam15921  796 RSQERRLKEKVANMEVALDKASLQF 820
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 182-412 1.19e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 182 ETALTEIDILNKSLIVSQRNKVCLEKEmknLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKL 261
Cdd:COG4942    30 EQLQQEIAELEKELAALKKEEKALLKQ---LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 262 QKAVTEM-----DNYKEMLMNksneADDCQRELRKLKFESVISESQhtmllkekedslmtcqqiyRALQEELTAKEKQEE 336
Cdd:COG4942   107 AELLRALyrlgrQPPLALLLS----PEDFLDAVRRLQYLKYLAPAR-------------------REQAEELRADLAELA 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622904486 337 DIKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAELAKERAQ 412
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 307-638 1.79e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 307 LKEKEDSLMTCQQIYRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELMlishQKSIEQLQE 386
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL----RAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 387 TLRQKLLSddnwkekieaelakerAQHLVEFEEQALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLitgatR 466
Cdd:COG4942   105 ELAELLRA----------------LYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL-----A 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 467 DLRQEVTALREKLheshiryteeseskekeienlknlvaefesrlkkeidsndsvsEDLRKEMKQKSDELKRVMLAQTQL 546
Cdd:COG4942   164 ALRAELEAERAEL-------------------------------------------EALLAELEEERAALEALKAERQKL 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 547 IEQFNKSQEEntfLQETVRRECEERFELTEALSQAREQLLELRKLRGSLPFSPcslSKGSLTSPAAA--VSNHGERSLAR 624
Cdd:COG4942   201 LARLEKELAE---LAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA---LKGKLPWPVSGrvVRRFGERDGGG 274

                         330
                  ....*....|....
gi 1622904486 625 LNSeKGIQIPSLRG 638
Cdd:COG4942   275 GRN-KGIDIAAPPG 287
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 331-595 3.46e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.82  E-value: 3.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  331 KEKQEEDIKRrinlAENELEITKTLLNQTREEVLTLKNERElMLISHQKSIEQLQETlRQKLLSddNWKEKIEAELAKER 410
Cdd:TIGR02169  172 KEKALEELEE----VEENIERLDLIIDEKRQQLERLRRERE-KAERYQALLKEKREY-EGYELL--KEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  411 AQhLVEFEEqallfkeetklqldiEKEKHQDIIQKYKKEQEELQMKISDLITGATRDLRQEVTALREKLHESHIRYTEES 490
Cdd:TIGR02169  244 RQ-LASLEE---------------ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  491 ESKEKEIENLKNLVAEfESRLKKEIDSNDSVSEDLRKEMKQKSDELkrvmlaqTQLIEQFNKSQEENTFLQETVRRECEE 570
Cdd:TIGR02169  308 RSIAEKERELEDAEER-LAKLEAEIDKLLAEIEELEREIEEERKRR-------DKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260
                   ....*....|....*....|....*
gi 1622904486  571 RFELTEALSQAREQLLELRKLRGSL 595
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINEL 404
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 319-590 3.72e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 40.59  E-value: 3.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  319 QIYRALQEELTAKEKQEEDIKRRINlAENELEITK-------TLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQK 391
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLES-AELRLSHLHfgyksdeTLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  392 LLSDDNWKEKIEAELAKERAQHLVeFE-----------EQALLFKEETKLQ---LDIEKEKHQDIIQKYK----KEQEEL 453
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGA-FLdadietaaadqEQLPSWQSELENLeerLKALTGKHQDVTAKYNrrrsKIKEQN 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  454 QMKISDL--------------ITGATRDLRQEVTALREKLHESHIRYTEESESKEKEIENLKNLV--AEFESRLKKEIDS 517
Cdd:pfam12128  389 NRDIAGIkdklakireardrqLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLnqATATPELLLQLEN 468

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622904486  518 NDSVSEDLRKEMKQKSDELKRVMLAQTQLIEQFNKS----QEENTFLQEtVRRECEerfELTEALSQAREQLLE-LRK 590
Cdd:pfam12128  469 FDERIERAREEQEAANAEVERLQSELRQARKRRDQAsealRQASRRLEE-RQSALD---ELELQLFPQAGTLLHfLRK 542
PRK12704 PRK12704
phosphodiesterase; Provisional
 261-429 4.51e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 4.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 261 LQKAVTEMDNYKEmlmNKSNEAddcQRELRKLKfesviseSQHTMLLKEKEDSLmtcQQIYRALQEELTAKEKQEEDIKR 340
Cdd:PRK12704   44 LEEAKKEAEAIKK---EALLEA---KEEIHKLR-------NEFEKELRERRNEL---QKLEKRLLQKEENLDRKLELLEK 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 341 RinlaENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQL----QETLRQKLLsddnwkEKIEAELAKERAQHLVE 416
Cdd:PRK12704  108 R----EEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERIsgltAEEAKEILL------EKVEEEARHEAAVLIKE 177

                         170
                  ....*....|...
gi 1622904486 417 FEEQAllfKEETK 429
Cdd:PRK12704  178 IEEEA---KEEAD 187
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 206-537 4.58e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 40.48  E-value: 4.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 206 EKEMKNLKLLSDAAILRSQQIQ-TSRQQEVNLQtrcyDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKEMLMNKSNEADD 284
Cdd:pfam05483 253 ENKMKDLTFLLEESRDKANQLEeKTKLQDENLK----ELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQ 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 285 CQRELRKLKFESVISESQHTMLLKEKEDSLMTCQQIYRALQEELTAKEKQEEDIKRRINLAENELEITKTLLNQTREEVL 364
Cdd:pfam05483 329 LTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 365 TLKN--ERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQDI 442
Cdd:pfam05483 409 ELKKilAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNI 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 443 iqkykkeqeELQMKiSDLITGATRDLRQEVTALREKLHESHIRYTEESESKEKEIENLKNLvAEFESRLKKEIDSndsvs 522
Cdd:pfam05483 489 ---------ELTAH-CDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENL-EEKEMNLRDELES----- 552

                         330
                  ....*....|....*
gi 1622904486 523 edLRKEMKQKSDELK 537
Cdd:pfam05483 553 --VREEFIQKGDEVK 565
PTZ00121 PTZ00121
MAEBL; Provisional
 273-590 4.93e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 4.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  273 EMLMNKSNEADDCQRELRKLKFESVISESQHTMLLKEKEDSLMTCQQIYRAlQEELTAKEKQEEDIKRRINLAENELEIT 352
Cdd:PTZ00121  1486 DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA-DEAKKAEEKKKADELKKAEELKKAEEKK 1564

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  353 KTllNQTREEvltlkNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAELAKERAQHLVEFEEqaLLFKEETKLQL 432
Cdd:PTZ00121  1565 KA--EEAKKA-----EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE--LKKAEEEKKKV 1635

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  433 DIEKEKHQDIIQK---YKKEQEELQMKISDLITGATRDLRQEVTALREKLHEShiryteeseskekeienlknlvaEFES 509
Cdd:PTZ00121  1636 EQLKKKEAEEKKKaeeLKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK-----------------------KAAE 1692

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  510 RLKKEIDSNDSVsEDLRK---EMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRRECEERFELTEALSQAREQLL 586
Cdd:PTZ00121  1693 ALKKEAEEAKKA-EELKKkeaEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771


                   ....
gi 1622904486  587 ELRK 590
Cdd:PTZ00121  1772 EIRK 1775
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 182-573 6.97e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 39.95  E-value: 6.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  182 ETALTEIDILNKSLIVSQRNKVCLEKEMKNLKLLSDAAILRSQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKL 261
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  262 QKAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISE-SQHTMLLKEKEDSLMTCQQIYRALQEELTAKEKQEEDiKR 340
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEeEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE-EL 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  341 RINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAELAkERAQHLVEFEEQ 420
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ-ELLLKEEELEEQ 882

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  421 ALLFKEETKLQLDIEKEKHQDIIQKYKKEQEELQMKISDLItgatrdlrQEVTALREKLHESHIRYTEESESKEKEIENL 500
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI--------KEEAEILLKYEEEPEELLLEEADEKEKEENN 954

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622904486  501 KNLVAEFESRLKKEIDsndsvsEDLRKEMKQKSDELKRVMLAQTQLIEQFNKSQEENTFLQETVRRECEERFE 573
Cdd:pfam02463  955 KEEEEERNKRLLLAKE------ELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 42-369 7.37e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 39.67  E-value: 7.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   42 EKVKAMEKEMKFYQgSVDREKRLQ-EKLHSLNQELEQYKIDSKSKTE-RIYDVGMQLKNQQNEFQKVEKQLSHLQDELKI 119
Cdd:TIGR02169  177 EELEEVEENIERLD-LIIDEKRQQlERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  120 KYRQSYIFSQRLSEYkyfwNKTLSLLTFTKRELTSiknevydnyqnwtslkgEIFLQIKSISETALTEIDILNKSLIVSQ 199
Cdd:TIGR02169  256 LTEEISELEKRLEEI----EQLLEELNKKIKDLGE-----------------EEQLRVKEKIGELEAEIASLERSIAEKE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  200 RNKVCLEKEMKNLKLLSDAAILR----SQQIQTSRQQEVNLQTRCYDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKEML 275
Cdd:TIGR02169  315 RELEDAEERLAKLEAEIDKLLAEieelEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  276 MNKSNEADDCQRELRKLKFESVISESQ---HTMLLKEKEDSLMTCQQIYRALQEELTAKEKQEEDIKRRINLAENELEIT 352
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEEladLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDL 474

                          330
                   ....*....|....*..
gi 1622904486  353 KTLLNQTREEVLTLKNE 369
Cdd:TIGR02169  475 KEEYDRVEKELSKLQRE 491
46 PHA02562
endonuclease subunit; Provisional
 185-440 8.83e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 39.23  E-value: 8.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 185 LTEIDILNKSLIVSqrnkvcLEKEMKNLKLLSDAAI--LRSQQIQTSRQQEVNlqtrcydlEQEVLDLQCLVEALGVKLQ 262
Cdd:PHA02562  165 LSEMDKLNKDKIRE------LNQQIQTLDMKIDHIQqqIKTYNKNIEEQRKKN--------GENIARKQNKYDELVEEAK 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 263 KAVTEMDNYKEMLMNKSNEADDCQRELRKLKFESVISESQHTMLLK-----EKEDSLMTCQQiyralqeELTAKEKQEED 337
Cdd:PHA02562  231 TIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKvikmyEKGGVCPTCTQ-------QISEGPDRITK 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486 338 IKRRINLAENELEitktLLNQTREEVltlkNERELMLISHQKSIEQLQ---ETLRQKLLSDDNWKEKIEAELAKERAQHL 414
Cdd:PHA02562  304 IKDKLKELQHSLE----KLDTAIDEL----EEIMDEFNEQSKKLLELKnkiSTNKQSLITLVDKAKKVKAAIEELQAEFV 375

                         250       260
                  ....*....|....*....|....*....
gi 1622904486 415 VEFEEQALLFKEETKL---QLDIEKEKHQ 440
Cdd:PHA02562  376 DNAEELAKLQDELDKIvktKSELVKEKYH 404
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 36-350 9.68e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 9.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486   36 EFKAMEEKVKAMEKEMkfyqgsvdreKRLQEKLHSLNQELEQYKIDSKSKTERIYDVGMQLKNQQNEFQKVEKQLSHLQD 115
Cdd:TIGR02168  685 KIEELEEKIAELEKAL----------AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  116 ELKIKYRQSYIFSQRLSEYKYFWNKTLSLLTFTKRELTSIKNEVYDNYQNWTSLKGEIFLQIKSISETALTeidilnksL 195
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER--------L 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622904486  196 IVSQRNKVCLEKEMKNLKllSDAAILRSQQIQTSRQQEvNLQTRCYDLEQEVLDLQCLVEALGVKLQKAVTEMDNYKEML 275
Cdd:TIGR02168  827 ESLERRIAATERRLEDLE--EQIEELSEDIESLAAEIE-ELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622904486  276 MNKSNEADDCQRELRKL--KFESVISESQHT-MLLKEKEDSLMTCQQIYRALQEELTAK-EKQEEDIKRRINLAENELE 350
Cdd:TIGR02168  904 RELESKRSELRRELEELreKLAQLELRLEGLeVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLENKIK 982
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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