U2 snRNP-associated SURP motif-containing protein isoform X4 [Macaca mulatta]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
RPR | smart00582 | domain present in proteins, which are involved in regulation of nuclear pre-mRNA; |
132-267 | 5.70e-31 | |||
domain present in proteins, which are involved in regulation of nuclear pre-mRNA; : Pssm-ID: 214731 Cd Length: 124 Bit Score: 116.99 E-value: 5.70e-31
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cwf21_SR140 | cd21370 | cwf21 domain found in U2-associated protein SR140 and similar proteins; SR140, also called U2 ... |
427-475 | 2.31e-22 | |||
cwf21 domain found in U2-associated protein SR140 and similar proteins; SR140, also called U2 snRNP-associated SURP motif-containing protein, U2SURP, or 140 kDa Ser/Arg-rich domain protein, is a putative splicing factor mainly found in higher eukaryotes. Although it was initially identified as a 17S U2 snRNP-associated protein, the molecular and physiological function of SR140 remains unclear. This model represents the cwf21 domain of SR140 and similar proteins. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. : Pssm-ID: 410597 Cd Length: 50 Bit Score: 90.34 E-value: 2.31e-22
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Surp | pfam01805 | Surp module; This domain is also known as the SWAP domain. SWAP stands for ... |
20-71 | 3.11e-20 | |||
Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding. : Pssm-ID: 460339 [Multi-domain] Cd Length: 52 Bit Score: 84.11 E-value: 3.11e-20
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Name | Accession | Description | Interval | E-value | |||
RPR | smart00582 | domain present in proteins, which are involved in regulation of nuclear pre-mRNA; |
132-267 | 5.70e-31 | |||
domain present in proteins, which are involved in regulation of nuclear pre-mRNA; Pssm-ID: 214731 Cd Length: 124 Bit Score: 116.99 E-value: 5.70e-31
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cwf21_SR140 | cd21370 | cwf21 domain found in U2-associated protein SR140 and similar proteins; SR140, also called U2 ... |
427-475 | 2.31e-22 | |||
cwf21 domain found in U2-associated protein SR140 and similar proteins; SR140, also called U2 snRNP-associated SURP motif-containing protein, U2SURP, or 140 kDa Ser/Arg-rich domain protein, is a putative splicing factor mainly found in higher eukaryotes. Although it was initially identified as a 17S U2 snRNP-associated protein, the molecular and physiological function of SR140 remains unclear. This model represents the cwf21 domain of SR140 and similar proteins. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Pssm-ID: 410597 Cd Length: 50 Bit Score: 90.34 E-value: 2.31e-22
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Surp | pfam01805 | Surp module; This domain is also known as the SWAP domain. SWAP stands for ... |
20-71 | 3.11e-20 | |||
Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding. Pssm-ID: 460339 [Multi-domain] Cd Length: 52 Bit Score: 84.11 E-value: 3.11e-20
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SWAP | smart00648 | Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ... |
19-73 | 3.34e-16 | |||
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes Pssm-ID: 197818 [Multi-domain] Cd Length: 54 Bit Score: 72.62 E-value: 3.34e-16
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CID_RPRD_like | cd16981 | CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing proteins; ... |
130-265 | 2.40e-09 | |||
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing proteins; This family is composed of Regulation of nuclear pre-mRNA domain-containing proteins 1A (RPRD1A), 1B (RPRD1B), 2 (RPRD2), yeast Rtt103, and similar proteins. RPRD1A, RPRD1B, and RPRD2 are CID (CTD-Interacting Domain) containing proteins that co-purify with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. Yeast transcription termination factor Rtt103 is a CID containing protein that functions in DNA damage response. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices. Pssm-ID: 340778 Cd Length: 125 Bit Score: 55.66 E-value: 2.40e-09
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CID | pfam04818 | CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase ... |
131-259 | 3.48e-09 | |||
CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase II. This domain is known as the CTD-interacting domain (CID). Pssm-ID: 461442 Cd Length: 117 Bit Score: 54.91 E-value: 3.48e-09
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cwf21 | pfam08312 | cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ... |
427-475 | 1.98e-06 | |||
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices. Pssm-ID: 462421 [Multi-domain] Cd Length: 44 Bit Score: 44.73 E-value: 1.98e-06
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Name | Accession | Description | Interval | E-value | |||
RPR | smart00582 | domain present in proteins, which are involved in regulation of nuclear pre-mRNA; |
132-267 | 5.70e-31 | |||
domain present in proteins, which are involved in regulation of nuclear pre-mRNA; Pssm-ID: 214731 Cd Length: 124 Bit Score: 116.99 E-value: 5.70e-31
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cwf21_SR140 | cd21370 | cwf21 domain found in U2-associated protein SR140 and similar proteins; SR140, also called U2 ... |
427-475 | 2.31e-22 | |||
cwf21 domain found in U2-associated protein SR140 and similar proteins; SR140, also called U2 snRNP-associated SURP motif-containing protein, U2SURP, or 140 kDa Ser/Arg-rich domain protein, is a putative splicing factor mainly found in higher eukaryotes. Although it was initially identified as a 17S U2 snRNP-associated protein, the molecular and physiological function of SR140 remains unclear. This model represents the cwf21 domain of SR140 and similar proteins. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Pssm-ID: 410597 Cd Length: 50 Bit Score: 90.34 E-value: 2.31e-22
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Surp | pfam01805 | Surp module; This domain is also known as the SWAP domain. SWAP stands for ... |
20-71 | 3.11e-20 | |||
Surp module; This domain is also known as the SWAP domain. SWAP stands for Suppressor-of-White-APricot. It has been suggested that these domains may be RNA binding. Pssm-ID: 460339 [Multi-domain] Cd Length: 52 Bit Score: 84.11 E-value: 3.11e-20
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SWAP | smart00648 | Suppressor-of-White-APricot splicing regulator; domain present in regulators which are ... |
19-73 | 3.34e-16 | |||
Suppressor-of-White-APricot splicing regulator; domain present in regulators which are responsible for pre-mRNA splicing processes Pssm-ID: 197818 [Multi-domain] Cd Length: 54 Bit Score: 72.62 E-value: 3.34e-16
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cwf21 | cd21369 | cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the ... |
427-475 | 2.03e-11 | |||
cwf21 domain; The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevents its binding to Prp8. The domain is composed of two alpha helices. Proteins containing the cwf21 domain include complexed with CEF1 protein 21 (CWC21) from budding yeast, complexed with cdc5 protein 21 (CWF21) from fission yeast, as well as their orthologs, serine/arginine repetitive matrix proteins (SRRM2 and SRRM3) from vertebrates. This domain family also includes U2-associated protein SR140 from Eumetazoa, protein RRC1, and similar proteins from plants. Pssm-ID: 410596 [Multi-domain] Cd Length: 48 Bit Score: 59.02 E-value: 2.03e-11
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CID_RPRD_like | cd16981 | CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing proteins; ... |
130-265 | 2.40e-09 | |||
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing proteins; This family is composed of Regulation of nuclear pre-mRNA domain-containing proteins 1A (RPRD1A), 1B (RPRD1B), 2 (RPRD2), yeast Rtt103, and similar proteins. RPRD1A, RPRD1B, and RPRD2 are CID (CTD-Interacting Domain) containing proteins that co-purify with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. Yeast transcription termination factor Rtt103 is a CID containing protein that functions in DNA damage response. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices. Pssm-ID: 340778 Cd Length: 125 Bit Score: 55.66 E-value: 2.40e-09
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CID | pfam04818 | CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase ... |
131-259 | 3.48e-09 | |||
CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase II. This domain is known as the CTD-interacting domain (CID). Pssm-ID: 461442 Cd Length: 117 Bit Score: 54.91 E-value: 3.48e-09
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cwf21 | pfam08312 | cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a ... |
427-475 | 1.98e-06 | |||
cwf21 domain; The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe. The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in the cwf21 domain prevent Prp8 from binding. The structure of this domain has recently been solved which shows this domain to be composed of two alpha helices. Pssm-ID: 462421 [Multi-domain] Cd Length: 44 Bit Score: 44.73 E-value: 1.98e-06
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cwf21_RRC1-like | cd21371 | cwf21 domain found in Arabidopsis thaliana protein RRC1 and similar proteins; RRC1, also ... |
427-474 | 1.20e-03 | |||
cwf21 domain found in Arabidopsis thaliana protein RRC1 and similar proteins; RRC1, also called reduced red-light responses in cry1cry2 background 1, is a SR-like splicing factor required for phytochrome B (phyB) signal transduction and involved in phyB-dependent alternative splicing. This subfamily also includes protein RRC1-like, which may also function as a SR-like splicing factor. SR family splicing factors are characterized by the presence of a domain rich in arginine and serine dipeptides, called the RS domain. This model represents the cwf21 domain of RRC1 and similar proteins. The cwf21 domain is involved in mRNA splicing; it binds directly to the spliceosomal protein Prp8. Pssm-ID: 410598 Cd Length: 50 Bit Score: 37.05 E-value: 1.20e-03
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CID_Pcf11 | cd16982 | CID (CTD-Interacting Domain) of Pcf11; Pcf11 is conserved across eukaryotes. The best studied ... |
134-227 | 3.97e-03 | |||
CID (CTD-Interacting Domain) of Pcf11; Pcf11 is conserved across eukaryotes. The best studied protein is Saccharomyces cerevisiae Pcf11, also called protein 1 of CF I, an essential subunit of the cleavage factor IA (CFIA) complex which is required for polyadenylation-dependent pre-mRNA 3'-end processing and RNA polymerase (Pol) II (RNAP II) transcription termination. Human Pcf11, also referred to as pre-mRNA cleavage complex 2 protein Pcf11, has been shown to enhance degradation of RNAP II-associated nascent RNA and transcriptional termination. The family also includes plant PCFS4 (Pcf11-similar-4 protein or Polyadenylation and cleavage factor homolog 4) and Caenorhabditis elegans Polyadenylation and cleavage factor homolog 11. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. Pcf11 CID preferentially interacts with CTD phosphorylated at Ser2. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices. Pssm-ID: 340779 Cd Length: 127 Bit Score: 37.93 E-value: 3.97e-03
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Blast search parameters | ||||
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