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Conserved domains on  [gi|1622825279|ref|XP_028699573|]
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adenylate kinase 2, mitochondrial isoform X3 [Macaca mulatta]

Protein Classification

adenylate kinase family protein( domain architecture ID 11426204)

adenylate kinase family protein such as adenylate kinase that catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0019205|GO:0005524|GO:0016310|GO:0006139
PubMed:  2841070|14568537|3023080

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-178 3.26e-91

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


:

Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 265.45  E-value: 3.26e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:COG0563    34 MLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGFILDGFPRTVAQAEALDELLAELGIKLDAVIEL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:COG0563   114 DVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLV 193

                         170
                  ....*....|....*...
gi 1622825279 161 AIDASQTPDVVFASILAA 178
Cdd:COG0563   194 EIDGEGSIEEVTADILAI 211
 
Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-178 3.26e-91

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 265.45  E-value: 3.26e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:COG0563    34 MLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGFILDGFPRTVAQAEALDELLAELGIKLDAVIEL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:COG0563   114 DVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLV 193

                         170
                  ....*....|....*...
gi 1622825279 161 AIDASQTPDVVFASILAA 178
Cdd:COG0563   194 EIDGEGSIEEVTADILAI 211
adk PRK00279
adenylate kinase; Reviewed
 1-181 1.30e-89

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 261.24  E-value: 1.30e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK00279   34 MLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNGFLLDGFPRTIPQAEALDEMLKELGIKLDAVIEI 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK00279  114 DVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLK 193

                         170       180
                  ....*....|....*....|.
gi 1622825279 161 AIDASQTPDVVFASILAAFSK 181
Cdd:PRK00279  194 KIDGTGSIDEVFADILKALGK 214
ADK pfam00406
Adenylate kinase;
1-156 2.58e-89

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 259.55  E-value: 2.58e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEkRKEKLDSVIEF 80
Cdd:pfam00406  30 LLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLDGFPRTVPQAEALEELLE-RGIKLDYVIEF 108

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKR 156
Cdd:pfam00406 109 DVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 1-180 2.06e-78

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 232.90  E-value: 2.06e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLET-PLCKNGFLLDGFPRTVRQAEMLDDLMekrKEKLDSVIE 79
Cdd:TIGR01351  33 LLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQnDDNENGFILDGFPRTLSQAEALDALL---EEPIDAVIE 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  80 FSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIH 159
Cdd:TIGR01351 110 LDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGIL 189

                         170       180
                  ....*....|....*....|.
gi 1622825279 160 SAIDASQTPDVVFASILAAFS 180
Cdd:TIGR01351 190 VQIDGNGPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 1-171 4.76e-74

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 221.34  E-value: 4.76e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKeKLDSVIEF 80
Cdd:cd01428    33 LLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGFILDGFPRTVDQAEALDELLDEGI-KPDKVIEL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEefnppkepMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:cd01428   112 DVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLV 183

                         170
                  ....*....|.
gi 1622825279 161 AIDASQTPDVV 171
Cdd:cd01428   184 EIDGSGDIDEV 194
 
Name Accession Description Interval E-value
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-178 3.26e-91

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 265.45  E-value: 3.26e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:COG0563    34 MLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANGFILDGFPRTVAQAEALDELLAELGIKLDAVIEL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:COG0563   114 DVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRADDNEETVRKRLEVYHEQTAPLIDYYRKKGKLV 193

                         170
                  ....*....|....*...
gi 1622825279 161 AIDASQTPDVVFASILAA 178
Cdd:COG0563   194 EIDGEGSIEEVTADILAI 211
adk PRK00279
adenylate kinase; Reviewed
 1-181 1.30e-89

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 261.24  E-value: 1.30e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK00279   34 MLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNGFLLDGFPRTIPQAEALDEMLKELGIKLDAVIEI 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK00279  114 DVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLK 193

                         170       180
                  ....*....|....*....|.
gi 1622825279 161 AIDASQTPDVVFASILAAFSK 181
Cdd:PRK00279  194 KIDGTGSIDEVFADILKALGK 214
ADK pfam00406
Adenylate kinase;
1-156 2.58e-89

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 259.55  E-value: 2.58e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEkRKEKLDSVIEF 80
Cdd:pfam00406  30 LLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLDGFPRTVPQAEALEELLE-RGIKLDYVIEF 108

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKR 156
Cdd:pfam00406 109 DVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNEETVKKRLETYHKQTKPLIDYYKKK 184
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 1-180 2.06e-78

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 232.90  E-value: 2.06e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLET-PLCKNGFLLDGFPRTVRQAEMLDDLMekrKEKLDSVIE 79
Cdd:TIGR01351  33 LLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQnDDNENGFILDGFPRTLSQAEALDALL---EEPIDAVIE 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  80 FSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIH 159
Cdd:TIGR01351 110 LDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDDTEEVVKKRLEVYKEQTEPLIDYYKKRGIL 189

                         170       180
                  ....*....|....*....|.
gi 1622825279 160 SAIDASQTPDVVFASILAAFS 180
Cdd:TIGR01351 190 VQIDGNGPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 1-171 4.76e-74

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 221.34  E-value: 4.76e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKeKLDSVIEF 80
Cdd:cd01428    33 LLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGFILDGFPRTVDQAEALDELLDEGI-KPDKVIEL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEefnppkepMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:cd01428   112 DVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSDDNEETIKKRLEVYKEQTAPLIDYYKKKGKLV 183

                         170
                  ....*....|.
gi 1622825279 161 AIDASQTPDVV 171
Cdd:cd01428   184 EIDGSGDIDEV 194
PLN02674 PLN02674
adenylate kinase
 1-180 2.77e-71

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 215.90  E-value: 2.77e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PLN02674   65 MLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLAKQGAKIDKVLNF 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PLN02674  145 AIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRKDDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVA 224

                         170       180
                  ....*....|....*....|
gi 1622825279 161 AIDASQTPDVVFASILAAFS 180
Cdd:PLN02674  225 NLHAEKPPKEVTAEVQKALS 244
PRK14532 PRK14532
adenylate kinase; Provisional
 1-182 8.90e-48

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 154.21  E-value: 8.90e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK14532   34 MLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAGGAIFDGFPRTVAQAEALDKMLASRGQKIDVVIRL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRlihpksgrsYHEEfnppkepmkdditgepliRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK14532  114 KVDDEALIERIVKR---------FEEQ------------------GRPDDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLT 166

                         170       180
                  ....*....|....*....|..
gi 1622825279 161 AIDASQTPDVVFASILAAFSKA 182
Cdd:PRK14532  167 EVDGMGSIEAVAASIDAALEGV 188
PRK14530 PRK14530
adenylate kinase; Provisional
 17-183 3.95e-42

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 140.69  E-value: 3.95e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  17 KATMDAGKLVSDEMVVELIEKNLETplcKNGFLLDGFPRTVRQAEMLDDLMEkrkekLDSVIEFSIPDSLLIRRITGRLI 96
Cdd:PRK14530   57 GEYMDAGELVPDAVVNEIVEEALSD---ADGFVLDGYPRNLEQAEYLESITD-----LDVVLYLDVSEEELVDRLTGRRV 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  97 HPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASIL 176
Cdd:PRK14530  129 CPDCGANYHVEFNQPEEEGVCDECGGELIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQ 208


                  ....*..
gi 1622825279 177 AAFSKAT 183
Cdd:PRK14530  209 DAIDDAT 215
adk PRK02496
adenylate kinase; Provisional
 1-178 1.40e-38

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 130.64  E-value: 1.40e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK02496   35 ILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANGWILDGFPRKVTQAAFLDELLQEIGQSGERVVNL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRlihpksgrsyheefnppkepmkdditgepliRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK02496  115 DVPDDVVVERLLAR-------------------------------GRKDDTEEVIRRRLEVYREQTAPLIDYYRDRQKLL 163

                         170
                  ....*....|....*...
gi 1622825279 161 AIDASQTPDVVFASILAA 178
Cdd:PRK02496  164 TIDGNQSVEAVTTELKAA 181
PRK13808 PRK13808
adenylate kinase; Provisional
 1-185 6.19e-36

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 128.08  E-value: 6.19e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK13808   34 MLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANGFILDGFPRTVPQAEALDALLKDKQLKLDAVVEL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSgrsyheefnppkepmkddiTGEPLirRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK13808  114 RVNEGALLARVETRVAEMRA-------------------RGEEV--RADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLL 172

                         170       180
                  ....*....|....*....|....*...
gi 1622825279 161 AIDASQTPDVVFASI---LAAFSKATCK 185
Cdd:PRK13808  173 TVDGMMTIDEVTREIgrvLAAVGAANAK 200
PRK14527 PRK14527
adenylate kinase; Provisional
 1-180 6.97e-35

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 121.44  E-value: 6.97e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLeTPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK14527   40 ILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDEL-AGMEPVRVIFDGFPRTLAQAEALDRLLEELGARLLAVVLL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLihpksgrsyHEEfnppkepmkdditgepliRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK14527  119 EVPDEELIRRIVERA---------RQE------------------GRSDDNEETVRRRQQVYREQTQPLVDYYEARGHLK 171

                         170       180
                  ....*....|....*....|
gi 1622825279 161 AIDASQTPDVVFASILAAFS 180
Cdd:PRK14527  172 RVDGLGTPDEVYARILKALG 191
PRK14528 PRK14528
adenylate kinase; Provisional
 1-176 9.97e-35

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 120.89  E-value: 9.97e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK14528   35 ILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQADALDALLKNEGKSIDKAINL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIhpKSGrsyheefnppkepmkdditgeplirRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK14528  115 EVPDGELLKRLLGRAE--IEG-------------------------RADDNEATIKNRLDNYNKKTLPLLDFYAAQKKLS 167

                         170
                  ....*....|....*.
gi 1622825279 161 AIDASQTPDVVFASIL 176
Cdd:PRK14528  168 QVNGVGSLEEVTSLIQ 183
PLN02842 PLN02842
nucleotide kinase
 1-181 8.63e-34

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 124.97  E-value: 8.63e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETP-LCKNGFLLDGFPRTVRQAEMLDDLmekrKEKLDSVIE 79
Cdd:PLN02842   31 LLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREdAKEKGWLLDGYPRSFAQAQSLEKL----KIRPDIFIL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  80 FSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPmkdDITGEpLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKrgIH 159
Cdd:PLN02842  107 LDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPESE---EIKAR-LITRPDDTEEKVKARLQIYKKNAEAILSTYSD--IM 180

                         170       180
                  ....*....|....*....|..
gi 1622825279 160 SAIDASQTPDVVFASILAAFSK 181
Cdd:PLN02842  181 VKIDGNRPKEVVFEEISSLLSQ 202
PRK14531 PRK14531
adenylate kinase; Provisional
 1-180 1.11e-33

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 117.99  E-value: 1.11e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETpLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEF 80
Cdd:PRK14531   36 LLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKA-LNSGGWLLDGFPRTVAQAEALEPLLEELKQPIEAVVLL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRlihpksgrsyheefnppkepmkdditgepliRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK14531  115 ELDDAVLIERLLAR-------------------------------GRADDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQ 163

                         170       180
                  ....*....|....*....|
gi 1622825279 161 AIDASQTPDVVFASILAAFS 180
Cdd:PRK14531  164 SVEAQGSIEAITERIEKVLA 183
PRK14526 PRK14526
adenylate kinase; Provisional
 1-181 3.41e-32

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 114.95  E-value: 3.41e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKekldsVIEF 80
Cdd:PRK14526   34 LFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNDNFILDGFPRNINQAKALDKFLPNIK-----IINF 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PRK14526  109 LIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDDKEESLKTRLQEYKLQTKPLIEFYSKCNRLN 188

                         170       180
                  ....*....|....*....|.
gi 1622825279 161 AIDASQTPDVVFASILAAFSK 181
Cdd:PRK14526  189 NIDASKDIDEVKKKLIEIISK 209
PLN02459 PLN02459
probable adenylate kinase
 1-157 1.82e-29

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 109.17  E-value: 1.82e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCK--NGFLLDGFPRTVRQAEMLDDLMEkrkekLDSVI 78
Cdd:PLN02459   63 LVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEEEgeSGFILDGFPRTVRQAEILEGVTD-----IDLVV 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  79 EFSIPDSLLIRRITGRLIHPKSGRSYH-----------------EEFNPPKEPMKDditgepLIRRSDDNEKALKIRLQA 141
Cdd:PLN02459  138 NLKLREEVLVEKCLGRRICSECGKNFNvadidlkgedgrpgivmPPLLPPPECASK------LITRADDTEEVVKARLRV 211

                         170
                  ....*....|....*.
gi 1622825279 142 YHTQTTPLIEYYRKRG 157
Cdd:PLN02459  212 YKEESQPVEDFYRKRG 227
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 1-182 1.27e-27

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 102.59  E-value: 1.27e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRTVRQAEMLddlmEKRKEKLDSVIE 79
Cdd:TIGR01360  37 LLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAMVAALGTSkGFLIDGYPREVKQGEEF----ERRIGPPTLVLY 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  80 FSIPDSLLIRRITGRliHPKSGRSyheefnppkepmkdditgeplirrsDDNEKALKIRLQAYHTQTTPLIEYYRKRGIH 159
Cdd:TIGR01360 113 FDCSEDTMVKRLLKR--AETSGRV-------------------------DDNEKTIKKRLETYYKATEPVIAYYETKGKL 165

                         170       180
                  ....*....|....*....|...
gi 1622825279 160 SAIDASQTPDVVFASILAAFSKA 182
Cdd:TIGR01360 166 RKINAEGTVDDVFLQVCTAIDKL 188
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 1-180 6.89e-25

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 95.52  E-value: 6.89e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVA-SGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKrKEKLDSVIE 79
Cdd:TIGR01359  33 LLRAEIKrEGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKKFLIDGFPRNEENLEAWEKLMDN-KVNFKFVLF 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  80 FSIPDSLLIRRITGRliHPKSGrsyheefnppkepmkdditgeplirRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIH 159
Cdd:TIGR01359 112 FDCPEETMIKRLLKR--GQTSG-------------------------RVDDNIETLKKRFRTYNEETLPIIEHFENKGKV 164

                         170       180
                  ....*....|....*....|.
gi 1622825279 160 SAIDASQTPDVVFASILAAFS 180
Cdd:TIGR01359 165 KEINAEGSVEEVFEDVEKIFA 185
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 1-158 5.03e-22

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 89.09  E-value: 5.03e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPL--CKNGFLLDGFPRTVRQAEMLDDLmekrkEKLDSVI 78
Cdd:PTZ00088   40 ILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVTddCFKGFILDGFPRNLKQCKELGKI-----TNIDLFV 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  79 EFSIPDSLLIRRITGRLIHPKSGRSYH------EEFN-PPKEPMKDDIT--GEP-LIRRSDDNEKALKIRLQAYHTQTTP 148
Cdd:PTZ00088  115 NIYLPRNILIKKLLGRRICNTCNRNFNiahirsDPYDmPPILPPADCEGckGNPkLQKRSDDTEEIVAHRLNTYESTNSP 194

                         170
                  ....*....|
gi 1622825279 149 LIEYYRKRGI 158
Cdd:PTZ00088  195 IIQFFKNENC 204
PRK14529 PRK14529
adenylate kinase; Provisional
 3-147 2.60e-19

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 81.69  E-value: 2.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   3 RAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPlCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSI 82
Cdd:PRK14529   36 REHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQD-GKNGWLLDGFPRNKVQAEKLWEALQKEGMKLDYVIEILL 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622825279  83 PDSLLIRRITGRLI------HPKSgrSYHEEFNPPKEpmKDDITGEPLIRRSDD-NEKALKIRLQAYHTQTT 147
Cdd:PRK14529  115 PREVAKNRIMGRRLckndnnHPNN--IFIDAIKPDGD--VCRVCGGELSTRADDqDEEAINKRHDIYYDTET 182
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 94-129 2.67e-17

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 71.34  E-value: 2.67e-17
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1622825279  94 RLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSD 129
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
PLN02200 PLN02200
adenylate kinase family protein
 1-180 2.43e-13

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 66.07  E-value: 2.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLcKNGFLLDGFPRTVRQAEMLDDLMekrKEKLDSVIEF 80
Cdd:PLN02200   77 LLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSD-NNKFLIDGFPRTEENRIAFERII---GAEPNVVLFF 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279  81 SIPDSLLIRRITGRlihpKSGrsyheefnppkepmkdditgeplirRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHS 160
Cdd:PLN02200  153 DCPEEEMVKRVLNR----NQG-------------------------RVDDNIDTIKKRLKVFNALNLPVIDYYSKKGKLY 203

                         170       180
                  ....*....|....*....|
gi 1622825279 161 AIDASQTPDVVFASILAAFS 180
Cdd:PLN02200  204 TINAVGTVDEIFEQVRPIFA 223
AAA_17 pfam13207
AAA domain;
1-104 8.81e-10

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 54.55  E-value: 8.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279   1 MLRAMVASGsELGKKLKAtMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKL--DSVI 78
Cdd:pfam13207  29 LLREEAKER-GLVEDRDE-MRKLPLEPQKELQKLAAERIAEEAGEGGVIVDGHPRIKTPAGYLPGLPVEVLRELkpDAII 106

                          90       100
                  ....*....|....*....|....*.
gi 1622825279  79 EFSIPDSLLIRRitgRLIHPKSGRSY 104
Cdd:pfam13207 107 LLEADPEEILER---RLKDRTRGRDD 129
BRO1_Rhophilin cd09244
Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin and related domains; ...
 108-187 9.08e-03

Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin and related domains; This family contains the Bro1-like domain of RhoA-binding proteins, Rhophilin-1 and -2, and related domains. It belongs to the BRO1_Alix_like superfamily which also includes the Bro1-like domains of mammalian Alix (apoptosis-linked gene-2 interacting protein X), His-Domain type N23 protein tyrosine phosphatase (HD-PTP, also known as PTPN23), Brox, Bro1 and Rim20 (also known as PalA) from Saccharomyces cerevisiae, Ustilago maydis Rim23 (also known as PalC), and related domains. Rhophilin-1 and -2 bind both GDP- and GTP-bound RhoA. Bro1-like domains are boomerang-shaped, and part of the domain is a tetratricopeptide repeat (TPR)-like structure. In addition to this Bro1-like domain, Rhophilin-1 and -2, contain an N-terminal Rho-binding domain and a C-terminal PDZ (PS.D.-95, Disc-large, ZO-1) domain. Their PDZ domains have limited homology. Rhophilin-1 and -2 have different activities. The Drosophila knockout of Rhophilin-1 is embryonic lethal, suggesting an essential role in embryonic development. Roles of Rhophilin-2 may include limiting stress fiber formation or increasing the turnover of F-actin in the absence of high levels of RhoA signaling activity. The isolated Bro1-like domain of Rhophilin-1 binds human immunodeficiency virus type 1 (HIV-1) nucleocapsid. This family lacks the V-shaped (V) domain found in many members of the BRO1_Alix _like superfamily.


Pssm-ID: 185767  Cd Length: 350  Bit Score: 36.17  E-value: 9.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622825279 108 FNPPKEPMK------DDITGEPLIRRSDDNEKA-LKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 180
Cdd:cd09244    74 FFPPDRSLGiyfhwyDSLTGVPSVQRSVAFEKAsVLFNIGALYTQIGAKQDRTTEEGIEAAVDAFQRAAGAFNYLRENFS 153


                  ....*..
gi 1622825279 181 KATCKDL 187
Cdd:cd09244   154 NAPSMDL 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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