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Conserved domains on  [gi|1622901602|ref|XP_028699238|]
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centrosomal protein of 70 kDa isoform X8 [Macaca mulatta]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
53-312 1.64e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602   53 KDLIIFDKQSSQRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRAtnqEQRANDLEQIMESVKSKIGELEde 132
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL---EEEIEELQKELYALANEISRLE-- 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  133 slNRACQQQNKIKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKE---EEDRIVTQNRVFAYLCKRVphTVL 209
Cdd:TIGR02168  302 --QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEElesLEAELEELEAELEELESRL--EEL 377
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  210 DRQLLCL---IDYYESKIRKIHTQRQYKEDE-SQSEEENDYRSLDASptykGLLMSLQ-NQLKESNSQIDALLSEKLNLQ 284
Cdd:TIGR02168  378 EEQLETLrskVAQLELQIASLNNEIERLEARlERLEDRRERLQQEIE----ELLKKLEeAELKELQAELEELEEELEELQ 453
                          250       260
                   ....*....|....*....|....*...
gi 1622901602  285 KDLETRptQHELRLYKQQVKKLEKALKK 312
Cdd:TIGR02168  454 EELERL--EEALEELREELEEAEQALDA 479
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
53-312 1.64e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602   53 KDLIIFDKQSSQRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRAtnqEQRANDLEQIMESVKSKIGELEde 132
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL---EEEIEELQKELYALANEISRLE-- 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  133 slNRACQQQNKIKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKE---EEDRIVTQNRVFAYLCKRVphTVL 209
Cdd:TIGR02168  302 --QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEElesLEAELEELEAELEELESRL--EEL 377
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  210 DRQLLCL---IDYYESKIRKIHTQRQYKEDE-SQSEEENDYRSLDASptykGLLMSLQ-NQLKESNSQIDALLSEKLNLQ 284
Cdd:TIGR02168  378 EEQLETLrskVAQLELQIASLNNEIERLEARlERLEDRRERLQQEIE----ELLKKLEeAELKELQAELEELEEELEELQ 453
                          250       260
                   ....*....|....*....|....*...
gi 1622901602  285 KDLETRptQHELRLYKQQVKKLEKALKK 312
Cdd:TIGR02168  454 EELERL--EEALEELREELEEAEQALDA 479
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
64-347 2.85e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  64 QRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELEdESLNRACQQqnk 143
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-QDIARLEER--- 310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 144 IKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRVfaylckrvphtvldrqllclidyyESK 223
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA------------------------EEA 366
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 224 IRKIHTQRQYKEDESQSEEENDYRSLDASPTYKGLLMSLQNQLKESNSQIDALLSEKLNLQKDLETRpTQHELRLYKQQV 303
Cdd:COG1196   367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL-EEEEEEEEEALE 445
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1622901602 304 KKLEKALKKSVKLQELISPKKAEDTEKKDEPSKYNQQQALIDQR 347
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
64-190 1.22e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  64 QRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELED---------ESL 134
Cdd:PRK02224  512 ERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSklaelkeriESL 591
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622901602 135 NRACQQQNKIKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKE-EEDRI 190
Cdd:PRK02224  592 ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEfDEARI 648
Tht1 pfam04163
Tht1-like nuclear fusion protein;
65-135 1.31e-03

Tht1-like nuclear fusion protein;


Pssm-ID: 282073  Cd Length: 595  Bit Score: 41.74  E-value: 1.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622901602  65 RMRQNLKLLVE-ETSRQQNMIQE--LIETNQQLRNELQLEHSRATNqeqRANDLEQIMESVKSKIGELEDESLN 135
Cdd:pfam04163 236 KVNDEIMGLVElENHEQEGMVLEkeIIEKIKQLKNEIDDIHHFFAD---FADELAGYKNDIIEKINDLKDDSEN 306
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
53-312 1.64e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602   53 KDLIIFDKQSSQRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRAtnqEQRANDLEQIMESVKSKIGELEde 132
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL---EEEIEELQKELYALANEISRLE-- 301
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  133 slNRACQQQNKIKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKE---EEDRIVTQNRVFAYLCKRVphTVL 209
Cdd:TIGR02168  302 --QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEElesLEAELEELEAELEELESRL--EEL 377
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  210 DRQLLCL---IDYYESKIRKIHTQRQYKEDE-SQSEEENDYRSLDASptykGLLMSLQ-NQLKESNSQIDALLSEKLNLQ 284
Cdd:TIGR02168  378 EEQLETLrskVAQLELQIASLNNEIERLEARlERLEDRRERLQQEIE----ELLKKLEeAELKELQAELEELEEELEELQ 453
                          250       260
                   ....*....|....*....|....*...
gi 1622901602  285 KDLETRptQHELRLYKQQVKKLEKALKK 312
Cdd:TIGR02168  454 EELERL--EEALEELREELEEAEQALDA 479
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
64-347 2.85e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  64 QRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELEdESLNRACQQqnk 143
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-QDIARLEER--- 310
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 144 IKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRVfaylckrvphtvldrqllclidyyESK 223
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA------------------------EEA 366
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 224 IRKIHTQRQYKEDESQSEEENDYRSLDASPTYKGLLMSLQNQLKESNSQIDALLSEKLNLQKDLETRpTQHELRLYKQQV 303
Cdd:COG1196   367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL-EEEEEEEEEALE 445
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1622901602 304 KKLEKALKKSVKLQELISPKKAEDTEKKDEPSKYNQQQALIDQR 347
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
64-327 1.19e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  64 QRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELEDESLnracQQQNK 143
Cdd:COG1196   270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE----ELEEE 345
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 144 IKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRvfaylckrvphtvldrqllclidyYESK 223
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE------------------------LAAQ 401
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 224 IRKIHTQRQYKEDESQSEEENDYRSLDASPTYKGLLMSLQNQLKESNSQIDALLSEKLNLQKDLETRptQHELRLYKQQV 303
Cdd:COG1196   402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL--LEEAALLEAAL 479
                         250       260
                  ....*....|....*....|....
gi 1622901602 304 KKLEKALKKSVKLQELISPKKAED 327
Cdd:COG1196   480 AELLEELAEAAARLLLLLEAEADY 503
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
64-190 1.22e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  64 QRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELED---------ESL 134
Cdd:PRK02224  512 ERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSklaelkeriESL 591
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622901602 135 NRACQQQNKIKDLQKEQKTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKE-EEDRI 190
Cdd:PRK02224  592 ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEfDEARI 648
Tht1 pfam04163
Tht1-like nuclear fusion protein;
65-135 1.31e-03

Tht1-like nuclear fusion protein;


Pssm-ID: 282073  Cd Length: 595  Bit Score: 41.74  E-value: 1.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622901602  65 RMRQNLKLLVE-ETSRQQNMIQE--LIETNQQLRNELQLEHSRATNqeqRANDLEQIMESVKSKIGELEDESLN 135
Cdd:pfam04163 236 KVNDEIMGLVElENHEQEGMVLEkeIIEKIKQLKNEIDDIHHFFAD---FADELAGYKNDIIEKINDLKDDSEN 306
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
70-333 1.47e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.59  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  70 LKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELED--ESLNRACQQQNKIKDL 147
Cdd:PRK03918  298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErhELYEEAKAKKEELERL 377
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 148 QKEQKTLQV-----KCQHYKKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRVFAY-----LCKRvphTVLDRQLLCLI 217
Cdd:PRK03918  378 KKRLTGLTPeklekELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpVCGR---ELTEEHRKELL 454
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 218 DYYESKIRKIHTQRQyKEDESQSEEENDYRSLDASPTYKGLLMSLQ---NQLKESNSQIDALLSEKLNlQKDLETRPTQH 294
Cdd:PRK03918  455 EEYTAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKLKelaEQLKELEEKLKKYNLEELE-KKAEEYEKLKE 532
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1622901602 295 ELRLYKQQVKKLEKALKksvKLQELISpKKAEDTEKKDE 333
Cdd:PRK03918  533 KLIKLKGEIKSLKKELE---KLEELKK-KLAELEKKLDE 567
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
75-325 2.69e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.13  E-value: 2.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  75 EETSRQQNMIQELIETNQQLRNELQLEHSRATNQeqrANDLEQIMESVKSKIGELEDEsLNracQQQNKIKDLQKEQKTL 154
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQ---LAALERRIAALARRIRALEQE-LA---ALEAELAELEKEIAEL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 155 QvkcqhykKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRVFAYLCKRV-PHTVLDRQLLCLIDYYESKIRKIHTQRQY 233
Cdd:COG4942    96 R-------AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqYLKYLAPARREQAEELRADLAELAALRAE 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 234 KEDESQSeeendyrsldasptykglLMSLQNQLKESNSQIDALLSEKLNLQKDLETR--PTQHELRLYKQQVKKLEKALK 311
Cdd:COG4942   169 LEAERAE------------------LEALLAELEEERAALEALKAERQKLLARLEKElaELAAELAELQQEAEELEALIA 230
                         250
                  ....*....|....
gi 1622901602 312 KSVKLQELISPKKA 325
Cdd:COG4942   231 RLEAEAAAAAERTP 244
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
58-320 2.74e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 2.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  58 FDKQSSQRMRQNLKLLVEETSRQQNMiqELIETNQQLRNELQL----EHSRATNQEQRanDLEQI-MESVKSKIGELEDE 132
Cdd:pfam17380 293 FEKMEQERLRQEKEEKAREVERRRKL--EEAEKARQAEMDRQAaiyaEQERMAMERER--ELERIrQEERKRELERIRQE 368
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 133 SLNRACQQQNKIKDLQ--KEQKTLQVK-----CQHYKKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRVF----AYLC 201
Cdd:pfam17380 369 EIAMEISRMRELERLQmeRQQKNERVRqeleaARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLeeerAREM 448
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602 202 KRVPHTVLDRQllclidyyeskiRKIHTQRQYKEDESQSEEENDYRSLDASPTYKGLLMSLQNQLKESNSQIDALLSEKL 281
Cdd:pfam17380 449 ERVRLEEQERQ------------QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRK 516
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1622901602 282 NLQKDLETRPT---QHELRLYKQQVKKLEKALKKSVKLQELI 320
Cdd:pfam17380 517 LLEKEMEERQKaiyEEERRREAEEERRKQQEMEERRRIQEQM 558
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
20-306 3.94e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 3.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602   20 TEKQQEEAEWESINVLLMMHGLKPLSLVKRTDLKDL---IIFDKQSSQRMRQNLKLLVEETSRQQNMIQELIETNQQLRN 96
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALrkdLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602   97 ELQLEHSRATNQEQRANDLEQIMESVKSKIGELEDE--SLN-RACQQQNKIKDLQKEQKTLQVKCQHYKKKRTEQQETIA 173
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAEltLLNeEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  174 SLQTEvcrLRKEEEDRIVTQNRVFAYLCKRVPHTVLDRQLLCLIDYYESKIRKIHTQRQYKEDESQS--EEENDYRSlda 251
Cdd:TIGR02168  856 SLAAE---IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEElrEKLAQLEL--- 929
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622901602  252 spTYKGLLMSLQNQLKESNS--QIDALLSEKLNLQKDLETRPTQHELRLYKQQVKKL 306
Cdd:TIGR02168  930 --RLEGLEVRIDNLQERLSEeySLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
50-285 5.13e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 5.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602   50 TDLKDLIIFDKQSSQRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGEL 129
Cdd:TIGR02168  270 EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  130 EdESLNRACQQQNKIKDLQKEQKT----LQVKCQHYKKKRTEQQETIASLQTEVCRLRKEEED----RIVTQNRVFAYLC 201
Cdd:TIGR02168  350 K-EELESLEAELEELEAELEELESrleeLEEQLETLRSKVAQLELQIASLNNEIERLEARLERledrRERLQQEIEELLK 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622901602  202 KRVPHTVLDRQLLClidyyESKIRKIHTQRQYKEDESQSEEENDYRSLDAsptyKGLLMSLQNQLKESNSQIDALLSEKL 281
Cdd:TIGR02168  429 KLEEAELKELQAEL-----EELEEELEELQEELERLEEALEELREELEEA----EQALDAAERELAQLQARLDSLERLQE 499

                   ....
gi 1622901602  282 NLQK 285
Cdd:TIGR02168  500 NLEG 503
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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