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Conserved domains on  [gi|1622910501|ref|XP_028696273|]
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dynein regulatory complex subunit 4 isoform X2 [Macaca mulatta]

Protein Classification

GAS domain-containing protein( domain architecture ID 12155935)

GAS (growth-arrest specific micro-tubule binding) domain-containing protein similar to Homo sapiens dynein regulatory complex subunit 4, also known as GAS-8/GAS-11, which is a component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes

Gene Ontology:  GO:0031514|GO:0048870

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
221-407 2.21e-72

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


:

Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 227.10  E-value: 2.21e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 221 TLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANY 300
Cdd:pfam13851   1 ELMKNHEKAFNEIKNYYNDITRNNLELIKSLKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLENY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 301 QRDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEK 380
Cdd:pfam13851  81 EKDKQSLKNLKARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYDKFEAAIQDVQQKTGLKNLLLEKKLQALGETLEK 160
                         170       180
                  ....*....|....*....|....*..
gi 1622910501 381 KEVQFNEVLAASNLDPAALTLVSRKLE 407
Cdd:pfam13851 161 KEAQLNEVLAAANLDPDALQAVTEKLE 187
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
64-375 7.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 7.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   64 EITRRQLEEKKAELRNKDREMEEAEERhqveikvyKQKVKHLLYEHQNNLTEMKAEgtvVMKLAQKEHRTQEGVLRKDMR 143
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEE--------IEELQKELYALANEISRLEQQ---KQILRERLANLERQLEELEAQ 324
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  144 ALKVELKEQELAnevvvknlrlkhtEEITKMRNDFERQVREIEAkydkkmkmLRDELDlrrktELHEVEERKNSQINTLM 223
Cdd:TIGR02168  325 LEELESKLDELA-------------EELAELEEKLEELKEELES--------LEAELE-----ELEAELEELESRLEELE 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  224 QRHEEAFTDIKNYYNDITLNNlALINSLKEQMEdmrkkedhleremaevsvqnkRLADPLQKAREEMSEMQKQLANYQRD 303
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLN-NEIERLEARLE---------------------RLEDRRERLQQEIEELLKKLEEAELK 436
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622910501  304 KqillcTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNlVLERKLQALS 375
Cdd:TIGR02168  437 E-----LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-SLERLQENLE 502
 
Name Accession Description Interval E-value
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
221-407 2.21e-72

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 227.10  E-value: 2.21e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 221 TLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANY 300
Cdd:pfam13851   1 ELMKNHEKAFNEIKNYYNDITRNNLELIKSLKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLENY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 301 QRDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEK 380
Cdd:pfam13851  81 EKDKQSLKNLKARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYDKFEAAIQDVQQKTGLKNLLLEKKLQALGETLEK 160
                         170       180
                  ....*....|....*....|....*..
gi 1622910501 381 KEVQFNEVLAASNLDPAALTLVSRKLE 407
Cdd:pfam13851 161 KEAQLNEVLAAANLDPDALQAVTEKLE 187
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
143-393 2.60e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 2.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  143 RALKVELKEQELANEVVVKNLRLKHTEEITKMRNDFERQVREIEAK---YDKKMKMLRDElDLRRKTELHEVE------- 212
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAElqeLEEKLEELRLE-VSELEEEIEELQkelyala 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  213 ---ERKNSQINTLMQRHEEAFTDIKnYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREE 289
Cdd:TIGR02168  295 neiSRLEQQKQILRERLANLERQLE-ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  290 MSEMQKQLaNYQRDKQILLctKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFT-AAIQEVQQKTGFKNLVLE 368
Cdd:TIGR02168  374 LEELEEQL-ETLRSKVAQL--ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELE 450
                          250       260
                   ....*....|....*....|....*
gi 1622910501  369 RKLQALSAAVEKKEVQFNEVLAASN 393
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQ 475
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
246-408 1.25e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 246 ALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQRDKQILlctKARLKVTEKELKDLQ 325
Cdd:COG1196   246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL---EERRRELEERLEELE 322
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 326 WEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRK 405
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                  ...
gi 1622910501 406 LEL 408
Cdd:COG1196   403 EEL 405
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
64-375 7.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 7.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   64 EITRRQLEEKKAELRNKDREMEEAEERhqveikvyKQKVKHLLYEHQNNLTEMKAEgtvVMKLAQKEHRTQEGVLRKDMR 143
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEE--------IEELQKELYALANEISRLEQQ---KQILRERLANLERQLEELEAQ 324
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  144 ALKVELKEQELAnevvvknlrlkhtEEITKMRNDFERQVREIEAkydkkmkmLRDELDlrrktELHEVEERKNSQINTLM 223
Cdd:TIGR02168  325 LEELESKLDELA-------------EELAELEEKLEELKEELES--------LEAELE-----ELEAELEELESRLEELE 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  224 QRHEEAFTDIKNYYNDITLNNlALINSLKEQMEdmrkkedhleremaevsvqnkRLADPLQKAREEMSEMQKQLANYQRD 303
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLN-NEIERLEARLE---------------------RLEDRRERLQQEIEELLKKLEEAELK 436
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622910501  304 KqillcTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNlVLERKLQALS 375
Cdd:TIGR02168  437 E-----LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-SLERLQENLE 502
PTZ00121 PTZ00121
MAEBL; Provisional
69-383 1.01e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   69 QLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGtvvMKLAQKEHRTQEGVLRKDMRALKVE 148
Cdd:PTZ00121  1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE---AKKAEEKKKADELKKAEELKKAEEK 1563
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  149 LKEQELANEVVVKNLRLKHTEEITKMRndfERQVREIEAKYDKKMKM----LRDELDLRRKTELHEVEERKNSQINTLMQ 224
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAE---EARIEEVMKLYEEEKKMkaeeAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  225 RHEEAftdiknyynditlnnlalinslKEQMEDMRKKEDHLE---REMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQ 301
Cdd:PTZ00121  1641 KEAEE----------------------KKKAEELKKAEEENKikaAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  302 RDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKK 381
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778

                   ..
gi 1622910501  382 EV 383
Cdd:PTZ00121  1779 AV 1780
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
55-359 1.39e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  55 ERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIkvykQKVKHLLYEHQnnltemkaegtvvmKLAQKEHRTQ 134
Cdd:pfam17380 289 QQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEM----DRQAAIYAEQE--------------RMAMEREREL 350
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 135 EGVLRKDMRALKVELKEQELANEVVvknlRLKHTEEITKMRNDFERQVREiEAKYDKKMKMLRDELDLRRKTELHEVEER 214
Cdd:pfam17380 351 ERIRQEERKRELERIRQEEIAMEIS----RMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQRKIQQQKVEMEQI 425
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 215 KNSQINTL---MQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEms 291
Cdd:pfam17380 426 RAEQEEARqreVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE-- 503
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622910501 292 emqkqlanyqrDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQK 359
Cdd:pfam17380 504 -----------RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRK 560
 
Name Accession Description Interval E-value
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
221-407 2.21e-72

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 227.10  E-value: 2.21e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 221 TLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANY 300
Cdd:pfam13851   1 ELMKNHEKAFNEIKNYYNDITRNNLELIKSLKEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLENY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 301 QRDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEK 380
Cdd:pfam13851  81 EKDKQSLKNLKARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYDKFEAAIQDVQQKTGLKNLLLEKKLQALGETLEK 160
                         170       180
                  ....*....|....*....|....*..
gi 1622910501 381 KEVQFNEVLAASNLDPAALTLVSRKLE 407
Cdd:pfam13851 161 KEAQLNEVLAAANLDPDALQAVTEKLE 187
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
143-393 2.60e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 2.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  143 RALKVELKEQELANEVVVKNLRLKHTEEITKMRNDFERQVREIEAK---YDKKMKMLRDElDLRRKTELHEVE------- 212
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAElqeLEEKLEELRLE-VSELEEEIEELQkelyala 294
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  213 ---ERKNSQINTLMQRHEEAFTDIKnYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREE 289
Cdd:TIGR02168  295 neiSRLEQQKQILRERLANLERQLE-ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  290 MSEMQKQLaNYQRDKQILLctKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFT-AAIQEVQQKTGFKNLVLE 368
Cdd:TIGR02168  374 LEELEEQL-ETLRSKVAQL--ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELE 450
                          250       260
                   ....*....|....*....|....*
gi 1622910501  369 RKLQALSAAVEKKEVQFNEVLAASN 393
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQ 475
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
68-379 6.81e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 6.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   68 RQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRTQEGVLRKDMRALKV 147
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  148 ELKEQELANEVVVKNLRLKHTE-EITKMRNDFERQVREIEAkYDKKMKMLRDELDlRRKTELHEVEERKNSQINTlMQRH 226
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEaEIEELEAQIEQLKEELKA-LREALDELRAELT-LLNEEAANLRERLESLERR-IAAT 836
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  227 EEAFTDIKNyyndITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQRDKQI 306
Cdd:TIGR02168  837 ERRLEDLEE----QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622910501  307 LlctKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVE 379
Cdd:TIGR02168  913 L---RRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
64-379 7.42e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 7.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   64 EITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKA-EGTVVMKLAQKEHRTQE-GVLRKD 141
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAiERQLASLEEELEKLTEEiSELEKR 266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  142 MRALKVELKEQELANEVVVKNLRLKHTEEITKMRNDFERQVREIEAKYDKKMKMLR----DELDLRRKTELHEVEERKNS 217
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEErlakLEAEIDKLLAEIEELEREIE 346
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  218 QINTLMQRHEEAFTDIKNYYNDItLNNLALINS----LKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEM 293
Cdd:TIGR02169  347 EERKRRDKLTEEYAELKEELEDL-RAELEEVDKefaeTRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL 425
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  294 QKQLAnyqRDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQErdelYRKFTAAIQEVQQKTGFKNLVLERKLQA 373
Cdd:TIGR02169  426 NAAIA---GIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE----LYDLKEEYDRVEKELSKLQRELAEAEAQ 498

                   ....*.
gi 1622910501  374 LSAAVE 379
Cdd:TIGR02169  499 ARASEE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
246-408 1.25e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.54  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 246 ALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQRDKQILlctKARLKVTEKELKDLQ 325
Cdd:COG1196   246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL---EERRRELEERLEELE 322
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 326 WEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRK 405
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                  ...
gi 1622910501 406 LEL 408
Cdd:COG1196   403 EEL 405
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
68-391 2.63e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 2.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   68 RQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEhqnnltemkaegtvvMKLAQKEHRTQEgvlrkdmralkv 147
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE---------------LSDASRKIGEIE------------ 722
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  148 elKEQELANEVVVKNlrlkhTEEITKMRNDFERQVREIEAkYDKKMKMLRDELDlRRKTELHEVEErknsQINTLMQRHE 227
Cdd:TIGR02169  723 --KEIEQLEQEEEKL-----KERLEELEEDLSSLEQEIEN-VKSELKELEARIE-ELEEDLHKLEE----ALNDLEARLS 789
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  228 EAFTDIKNyynditlnnlALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQRDKQIL 307
Cdd:TIGR02169  790 HSRIPEIQ----------AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL 859
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  308 lctKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAaiqevqqktgfknlvLERKLQALSAAVEKKEVQFNE 387
Cdd:TIGR02169  860 ---NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE---------------LERKIEELEAQIEKKRKRLSE 921

                   ....
gi 1622910501  388 VLAA 391
Cdd:TIGR02169  922 LKAK 925
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
64-375 7.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 7.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   64 EITRRQLEEKKAELRNKDREMEEAEERhqveikvyKQKVKHLLYEHQNNLTEMKAEgtvVMKLAQKEHRTQEGVLRKDMR 143
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEE--------IEELQKELYALANEISRLEQQ---KQILRERLANLERQLEELEAQ 324
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  144 ALKVELKEQELAnevvvknlrlkhtEEITKMRNDFERQVREIEAkydkkmkmLRDELDlrrktELHEVEERKNSQINTLM 223
Cdd:TIGR02168  325 LEELESKLDELA-------------EELAELEEKLEELKEELES--------LEAELE-----ELEAELEELESRLEELE 378
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  224 QRHEEAFTDIKNYYNDITLNNlALINSLKEQMEdmrkkedhleremaevsvqnkRLADPLQKAREEMSEMQKQLANYQRD 303
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLN-NEIERLEARLE---------------------RLEDRRERLQQEIEELLKKLEEAELK 436
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622910501  304 KqillcTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNlVLERKLQALS 375
Cdd:TIGR02168  437 E-----LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD-SLERLQENLE 502
PTZ00121 PTZ00121
MAEBL; Provisional
69-383 1.01e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   69 QLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGtvvMKLAQKEHRTQEGVLRKDMRALKVE 148
Cdd:PTZ00121  1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE---AKKAEEKKKADELKKAEELKKAEEK 1563
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  149 LKEQELANEVVVKNLRLKHTEEITKMRndfERQVREIEAKYDKKMKM----LRDELDLRRKTELHEVEERKNSQINTLMQ 224
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAE---EARIEEVMKLYEEEKKMkaeeAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  225 RHEEAftdiknyynditlnnlalinslKEQMEDMRKKEDHLE---REMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQ 301
Cdd:PTZ00121  1641 KEAEE----------------------KKKAEELKKAEEENKikaAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  302 RDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKK 381
Cdd:PTZ00121  1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778

                   ..
gi 1622910501  382 EV 383
Cdd:PTZ00121  1779 AV 1780
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
191-397 1.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 191 KKMKMLRDELDLRRKT--ELHEVEERKNSQINTLMQRHEEAFTDIKNYYNDITLNNlALINSLKEQMEDMRKKEDHLERE 268
Cdd:COG4942    27 AELEQLQQEIAELEKElaALKKEEKALLKQLAALERRIAALARRIRALEQELAALE-AELAELEKEIAELRAELEAQKEE 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 269 MAEVSVQNKRL------------ADPLQKAREEM------SEMQKQLANYQRDKQILLCTKARLKVTEKELKDLQWEHEV 330
Cdd:COG4942   106 LAELLRALYRLgrqpplalllspEDFLDAVRRLQylkylaPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622910501 331 LEQRFTKVQQERDELYRKFTAAIQEVQQKTGfKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPA 397
Cdd:COG4942   186 ERAALEALKAERQKLLARLEKELAELAAELA-ELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
55-359 1.39e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.26  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  55 ERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIkvykQKVKHLLYEHQnnltemkaegtvvmKLAQKEHRTQ 134
Cdd:pfam17380 289 QQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEM----DRQAAIYAEQE--------------RMAMEREREL 350
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 135 EGVLRKDMRALKVELKEQELANEVVvknlRLKHTEEITKMRNDFERQVREiEAKYDKKMKMLRDELDLRRKTELHEVEER 214
Cdd:pfam17380 351 ERIRQEERKRELERIRQEEIAMEIS----RMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQRKIQQQKVEMEQI 425
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 215 KNSQINTL---MQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEms 291
Cdd:pfam17380 426 RAEQEEARqreVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE-- 503
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622910501 292 emqkqlanyqrDKQILLCTKARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQK 359
Cdd:pfam17380 504 -----------RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRK 560
Rabaptin pfam03528
Rabaptin;
55-378 3.96e-03

Rabaptin;


Pssm-ID: 367545 [Multi-domain]  Cd Length: 486  Bit Score: 39.70  E-value: 3.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  55 ERDKIHTFWEITRRQLEEKKAELRNKDREM----EEAEERHQVEIKVYKQKVKHL---LYEHQNNLTEMKAEGTV----- 122
Cdd:pfam03528  12 ELEKENAEFYRLKQQLEAEFNQKRAKFKELylakEEDLKRQNAVLQEAQVELDALqnqLALARAEMENIKAVATVsentk 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 123 ------VMKLAQKEHRTQEGVLRKDMRALKVELK---EQELAN--------EVVVKNLRLKHTE---------EITKMRN 176
Cdd:pfam03528  92 qeaideVKSQWQEEVASLQAIMKETVREYEVQFHrrlEQERAQwnqyresaEREIADLRRRLSEgqeeenledEMKKAQE 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 177 DFERqVREIEAKYDKKMKMLRDELdLRRKTELHEVEERKNSQINTLMQRHEEAFTDIKNYynditlnnLALINS----LK 252
Cdd:pfam03528 172 DAEK-LRSVVMPMEKEIAALKAKL-TEAEDKIKELEASKMKELNHYLEAEKSCRTDLEMY--------VAVLNTqksvLQ 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 253 EQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQRDKQILLCTKARLKVTEKELKDlQWEHEVLE 332
Cdd:pfam03528 242 EDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMESVLTSEQLRQVEEIKKKD-QEEHKRAR 320
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1622910501 333 QRFTKVQQERDELY-RKFTAAIQEVQQKTGFKNLVLERKLQALSAAV 378
Cdd:pfam03528 321 THKEKETLKSDREHtVSIHAVFSPAGVETSAPLSNVEEQINSAHGSV 367
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
129-408 4.65e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 4.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 129 KEHRTQEGVLRKDMRALKVELKEQELANEVVVKNLRLKHTEEITKMRNDFERQVREIEAKYDKkmkmLRDELDLRRKTEL 208
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE----LELELEEAQAEEY 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 209 HEVEE--RKNSQINTLMQRHEEAFTDIKNYYNDItLNNLALINSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKA 286
Cdd:COG1196   292 ELLAElaRLEQDIARLEERRRELEERLEELEEEL-AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 287 REEMSEMQKQLANYQRDKQILLctkARLKVTEKELKDLQWEHEVLEQRFTKVQQERDELY-------RKFTAAIQEVQQK 359
Cdd:COG1196   371 EAELAEAEEELEELAEELLEAL---RAAAELAAQLEELEEAEEALLERLERLEEELEELEealaeleEEEEEEEEALEEA 447
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1622910501 360 TGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRKLEL 408
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
194-398 6.32e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 38.78  E-value: 6.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 194 KMLRDELDLRRKTELHEVEERKNSQINTLMQRHE-----EAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLERE 268
Cdd:PTZ00436   43 KLIKDGLIIRKPVKVHSRSRWRHMKEAKSMGRHEgagrrEGTREARMPSKELWMRRLRILRRLLRKYREEKKIDRHIYRE 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501 269 MAEvsvqnKRLADPLQKAREEMSEMQKQLANYQRDKQIllctkaRLKVTEKELKDLQWEHEVLEQRFTKVQQERDELYRK 348
Cdd:PTZ00436  123 LYV-----KAKGNVFRNKRNLMEHIHKVKNEKKKERQL------AEQLAAKRLKDEQHRHKARKQELRKREKDRERARRE 191
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1622910501 349 FTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAA 398
Cdd:PTZ00436  192 DAAAAAAAKQKAAAKKAAAPSGKKSAKAAAPAKAAAAPAKAAAPPAKAAA 241
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
228-388 6.94e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.88  E-value: 6.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  228 EAFTDIKNYYNDITLNNLAL-INSLKEQMEDMRKKEDHLEREMAEVSVQNKRLADPLQKAREEMSEMQKQLANYQRDKQI 306
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYA 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  307 LLCTKARL----KVTEKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQ----KTGFKNLV--LERKLQALSA 376
Cdd:TIGR02168  293 LANEISRLeqqkQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEElkeeLESLEAELeeLEAELEELES 372
                          170
                   ....*....|..
gi 1622910501  377 AVEKKEVQFNEV 388
Cdd:TIGR02168  373 RLEELEEQLETL 384
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
69-380 8.98e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 38.56  E-value: 8.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501   69 QLEEKKAELRNKdreMEEAEERHQveikvykQKVKHLLYEHQNNLTEMKAEGTvvmklaqkEHRTQEGVLRKDMRALKVE 148
Cdd:pfam15921  246 QLEALKSESQNK---IELLLQQHQ-------DRIEQLISEHEVEITGLTEKAS--------SARSQANSIQSQLEIIQEQ 307
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  149 LKEQelanevvvKNLRLKHTEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRK--TELHEVEERKNSQINTLMQRH 226
Cdd:pfam15921  308 ARNQ--------NSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSelTEARTERDQFSQESGNLDDQL 379
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  227 EEAFTDIKNYYNDITLNnlalinslKEQMEDMRKKE-------DHLEREMAEVSVQNKRLADPLQKAREE-MSEMQKQLA 298
Cdd:pfam15921  380 QKLLADLHKREKELSLE--------KEQNKRLWDRDtgnsitiDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMA 451
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622910501  299 NYQRDKQIL---LCTKARLKVTEKELKDLQweHEVLEQRFTKVQQERDelYRKFTAAIQEVqqktgfknlvlERKLQALS 375
Cdd:pfam15921  452 AIQGKNESLekvSSLTAQLESTKEMLRKVV--EELTAKKMTLESSERT--VSDLTASLQEK-----------ERAIEATN 516

                   ....*
gi 1622910501  376 AAVEK 380
Cdd:pfam15921  517 AEITK 521
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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