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Conserved domains on  [gi|1622834790|ref|XP_028695102|]
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protein FAM131C isoform X3 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM131 super family cl20887
Putative cell signalling; The precise function of this protein family is unknown, however ...
 19-185 8.66e-38

Putative cell signalling; The precise function of this protein family is unknown, however studies have shown it undergoes Protein N-myristoylation; a type of lipid modification in eukaryotic and viral proteins. Protein N-myristoylation is usually an irreversible co-translational protein modification which is useful in cell signal transduction pathways. This indicates that FAM131 may have some sort of role in cell signalling due to its ability to be myristoylated. This family of proteins is found in eukaryotes and are typically between 257 and 361 amino acids in length.


The actual alignment was detected with superfamily member pfam15010:

Pssm-ID: 464442  Cd Length: 292  Bit Score: 133.16  E-value: 8.66e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834790  19 LSDSRSCPSNYNVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSAQRAGWELSPAEDEHYCCLPDELREAR 98
Cdd:pfam15010   2 LPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPQDSPAALESDFNSYSDLSEGEQEAR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834790  99 FAAGVAEQFAITEATLSAWSSLD---------DEELYPENSPqgifqlqDLESIYLQDSLPSGPSQDDSL--QAFSSPSL 167
Cdd:pfam15010  82 FAAGVAEQFAIAEAKLRAWSSVDgedsnddsyDEDFAPATEP-------TMQSQDNAAQYPLGPWLHDYLhsGRCQSRPL 154

                         170
                  ....*....|....*...
gi 1622834790 168 SPESCPSLEEPPSTAGIP 185
Cdd:pfam15010 155 RQGSCEPESDGSQTVGSP 172
 
Name Accession Description Interval E-value
FAM131 pfam15010
Putative cell signalling; The precise function of this protein family is unknown, however ...
 19-185 8.66e-38

Putative cell signalling; The precise function of this protein family is unknown, however studies have shown it undergoes Protein N-myristoylation; a type of lipid modification in eukaryotic and viral proteins. Protein N-myristoylation is usually an irreversible co-translational protein modification which is useful in cell signal transduction pathways. This indicates that FAM131 may have some sort of role in cell signalling due to its ability to be myristoylated. This family of proteins is found in eukaryotes and are typically between 257 and 361 amino acids in length.


Pssm-ID: 464442  Cd Length: 292  Bit Score: 133.16  E-value: 8.66e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834790  19 LSDSRSCPSNYNVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSAQRAGWELSPAEDEHYCCLPDELREAR 98
Cdd:pfam15010   2 LPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPQDSPAALESDFNSYSDLSEGEQEAR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834790  99 FAAGVAEQFAITEATLSAWSSLD---------DEELYPENSPqgifqlqDLESIYLQDSLPSGPSQDDSL--QAFSSPSL 167
Cdd:pfam15010  82 FAAGVAEQFAIAEAKLRAWSSVDgedsnddsyDEDFAPATEP-------TMQSQDNAAQYPLGPWLHDYLhsGRCQSRPL 154

                         170
                  ....*....|....*...
gi 1622834790 168 SPESCPSLEEPPSTAGIP 185
Cdd:pfam15010 155 RQGSCEPESDGSQTVGSP 172
 
Name Accession Description Interval E-value
FAM131 pfam15010
Putative cell signalling; The precise function of this protein family is unknown, however ...
 19-185 8.66e-38

Putative cell signalling; The precise function of this protein family is unknown, however studies have shown it undergoes Protein N-myristoylation; a type of lipid modification in eukaryotic and viral proteins. Protein N-myristoylation is usually an irreversible co-translational protein modification which is useful in cell signal transduction pathways. This indicates that FAM131 may have some sort of role in cell signalling due to its ability to be myristoylated. This family of proteins is found in eukaryotes and are typically between 257 and 361 amino acids in length.


Pssm-ID: 464442  Cd Length: 292  Bit Score: 133.16  E-value: 8.66e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834790  19 LSDSRSCPSNYNVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSAQRAGWELSPAEDEHYCCLPDELREAR 98
Cdd:pfam15010   2 LPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPQDSPAALESDFNSYSDLSEGEQEAR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834790  99 FAAGVAEQFAITEATLSAWSSLD---------DEELYPENSPqgifqlqDLESIYLQDSLPSGPSQDDSL--QAFSSPSL 167
Cdd:pfam15010  82 FAAGVAEQFAIAEAKLRAWSSVDgedsnddsyDEDFAPATEP-------TMQSQDNAAQYPLGPWLHDYLhsGRCQSRPL 154

                         170
                  ....*....|....*...
gi 1622834790 168 SPESCPSLEEPPSTAGIP 185
Cdd:pfam15010 155 RQGSCEPESDGSQTVGSP 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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