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Conserved domains on  [gi|1622834693|ref|XP_028694872|]
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rootletin isoform X5 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 293-820 3.28e-28

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 124.28  E-value: 3.28e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  293 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 372
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  373 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 452
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  453 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL 532
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  533 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLeqQLPTLRHERSRLQEQLAQLSRQLSGREQE 612
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  613 LEQA--RRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARR 690
Cdd:COG1196    540 LEAAlaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  691 EHLEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAA 768
Cdd:COG1196    620 DTLLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834693  769 WRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE 820
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 581-1137 1.77e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.50  E-value: 1.77e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  581 LEQQLPTLRHERSRlqeqlAQLSRQLSGREQELEQARRAAQRQ--MEALERAAREKEALAKERAGLAVQLAAAEREGRTL 658
Cdd:COG1196    198 LERQLEPLERQAEK-----AERYRELKEELKELEAELLLLKLRelEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  659 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEK--ASLDKELMAQKL 736
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEleELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  737 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE---------ELLARLEAEKEELSEEIAT 807
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  808 LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL 887
Cdd:COG1196    433 LEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  888 EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL-----RESQEGREVQRQEAG 962
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  963 ELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEAR 1042
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1043 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1122
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570
                   ....*....|....*
gi 1622834693 1123 RTRERRLLGSLEEAR 1137
Cdd:COG1196    752 ALEELPEPPDLEELE 766
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
1-95 2.99e-25

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 104.74  E-value: 2.99e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693    1 MLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFT 80
Cdd:pfam15035   96 LLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTAT 175

                           90
                   ....*....|....*
gi 1622834693   81 ERDLLQLGGELARTS 95
Cdd:pfam15035  176 ERDLSELKTEFSRTS 190
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 817-1620 2.46e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.69  E-value: 2.46e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  817 LLAESEKQQALSLKESEKT----ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD-RSTVNALTSELRDLRAQLEEAV 891
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  892 AAHaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 971
Cdd:TIGR02168  274 LEV----SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  972 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR- 1050
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKk 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1051 ----QMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1126
Cdd:TIGR02168  430 leeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1127 RRLLGSLEEA--RGTEKQQLDHARGLELKLEATraeaaeLGLRLSAAEGRaqGLEAELARVEAQR-----RAAEAQLGGL 1199
Cdd:TIGR02168  510 ALLKNQSGLSgiLGVLSELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKqnelgRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1200 RSALRRGLGLGRAPS------PAPRPVPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAppdLDPETVR-- 1271
Cdd:TIGR02168  582 KGTEIQGNDREILKNiegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVT---LDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1272 ----GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlrarQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1347
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-------ELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1348 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1427
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1428 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSsaslns 1507
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL------ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1508 tqdknlhlqkaltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQE 1587
Cdd:TIGR02168  886 ---------------EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1622834693 1588 GEA-AALHMVQKLQDERRLLQERLGSLQRALAQL 1620
Cdd:TIGR02168  951 LTLeEAEALENKIEDDEEEARRRLKRLENKIKEL 984
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1518-1738 2.91e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1518 ALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQ 1597
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1598 KLQDERRLLQERLGSLQRALAQLEAEKR-----------EVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK 1666
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPlalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1667 GRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1738
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 293-820 3.28e-28

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 124.28  E-value: 3.28e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  293 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 372
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  373 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 452
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  453 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL 532
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  533 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLeqQLPTLRHERSRLQEQLAQLSRQLSGREQE 612
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  613 LEQA--RRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARR 690
Cdd:COG1196    540 LEAAlaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  691 EHLEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAA 768
Cdd:COG1196    620 DTLLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834693  769 WRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE 820
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 376-1196 5.19e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 120.55  E-value: 5.19e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  376 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrreLERSHRQLEQLEgkRSVLAKELVEVREALSRA 455
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAER--------YKELKAELRELE--LALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  456 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGR 535
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  536 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQ 615
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  616 ARRAAQRQMEALERAAREKEALAKERAglAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLE- 694
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEr 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  695 --AEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELM--AQKLVQAEREAQASLreqRAAHEEDLQRLQREKEAAWR 770
Cdd:TIGR02168  483 elAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvLSELISVDEGYEAAI---EAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  771 elEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLL----AESEKQQALS-------LKESEKTALsE 839
Cdd:TIGR02168  560 --KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkFDPKLRKALSyllggvlVVDDLDNAL-E 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  840 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL--TSELRDLRAQLEEavaahaqevrrLQEQAQDLGKQRDSCLR 917
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEE-----------LEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  918 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI 997
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  998 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1077
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1078 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAT 1157
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-RSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1622834693 1158 RAEAAELGLRlsAAEGRAQGLEAELARVEAQRRAAEAQL 1196
Cdd:TIGR02168  945 LSEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 581-1137 1.77e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.50  E-value: 1.77e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  581 LEQQLPTLRHERSRlqeqlAQLSRQLSGREQELEQARRAAQRQ--MEALERAAREKEALAKERAGLAVQLAAAEREGRTL 658
Cdd:COG1196    198 LERQLEPLERQAEK-----AERYRELKEELKELEAELLLLKLRelEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  659 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEK--ASLDKELMAQKL 736
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEleELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  737 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE---------ELLARLEAEKEELSEEIAT 807
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  808 LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL 887
Cdd:COG1196    433 LEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  888 EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL-----RESQEGREVQRQEAG 962
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  963 ELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEAR 1042
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1043 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1122
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570
                   ....*....|....*
gi 1622834693 1123 RTRERRLLGSLEEAR 1137
Cdd:COG1196    752 ALEELPEPPDLEELE 766
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
1-95 2.99e-25

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 104.74  E-value: 2.99e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693    1 MLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFT 80
Cdd:pfam15035   96 LLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTAT 175

                           90
                   ....*....|....*
gi 1622834693   81 ERDLLQLGGELARTS 95
Cdd:pfam15035  176 ERDLSELKTEFSRTS 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 817-1620 2.46e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.69  E-value: 2.46e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  817 LLAESEKQQALSLKESEKT----ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD-RSTVNALTSELRDLRAQLEEAV 891
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  892 AAHaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 971
Cdd:TIGR02168  274 LEV----SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  972 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR- 1050
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKk 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1051 ----QMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1126
Cdd:TIGR02168  430 leeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1127 RRLLGSLEEA--RGTEKQQLDHARGLELKLEATraeaaeLGLRLSAAEGRaqGLEAELARVEAQR-----RAAEAQLGGL 1199
Cdd:TIGR02168  510 ALLKNQSGLSgiLGVLSELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKqnelgRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1200 RSALRRGLGLGRAPS------PAPRPVPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAppdLDPETVR-- 1271
Cdd:TIGR02168  582 KGTEIQGNDREILKNiegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVT---LDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1272 ----GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlrarQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1347
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-------ELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1348 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1427
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1428 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSsaslns 1507
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL------ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1508 tqdknlhlqkaltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQE 1587
Cdd:TIGR02168  886 ---------------EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1622834693 1588 GEA-AALHMVQKLQDERRLLQERLGSLQRALAQL 1620
Cdd:TIGR02168  951 LTLeEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 524-1204 3.05e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.05e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  524 QLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS 603
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  604 RQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQL 683
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  684 AQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQR 763
Cdd:TIGR02168  396 ASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  764 EKEAAWRELEAERAQLQSQLQREqeELLARLEAEKEELSEEIATLQQERdEGLLLAESEKQQALSLKESEKTALSEKLMG 843
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARL--DSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  844 TRHSLATISLEMERQKRDAQSRQEQDRSTVNALTS-------ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCL 916
Cdd:TIGR02168  546 RLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgteiqGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  917 REAEELRTQLRLL------------------------------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRR 966
Cdd:TIGR02168  626 LVVDDLDNALELAkklrpgyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  967 SLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQ 1046
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1047 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL------QEQEG 1120
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1121 EFRTRERRLLGSLEEARGTEKQQLDHARgleLKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLR 1200
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLR---SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942


                   ....
gi 1622834693 1201 SALR 1204
Cdd:TIGR02168  943 ERLS 946
PTZ00121 PTZ00121
MAEBL; Provisional
 325-1015 2.66e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.04  E-value: 2.66e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  325 ERRALEEQLQRLRDKTDGAMQAQEDAqREVQRLRSANELLSREKSNLAHSLQVAQQ--QAEELRQEREKLQAAQEELRRQ 402
Cdd:PTZ00121  1138 DARKAEEARKAEDAKRVEIARKAEDA-RKAEEARKAEDAKKAEAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEE 1216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  403 RDRLEEEQE-DAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQrdmlqAEKAEVAEALTKAEAGRV 481
Cdd:PTZ00121  1217 ARKAEDAKKaEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK-----AEEARKADELKKAEEKKK 1291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  482 --ELELSMTKLRAEEASLQ-DSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRL 558
Cdd:PTZ00121  1292 adEAKKAEEKKKADEAKKKaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  559 EQEVARQGLEGSLRVAEQAQEVLEQQlptlrhERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALA 638
Cdd:PTZ00121  1372 KKEEAKKKADAAKKKAEEKKKADEAK------KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  639 KERAGLAVQLAAAEREGRTLSEEATRL-RLEKEALEG-SLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQ 716
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKAdEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD 1525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  717 QIIAIQEKASLDKELMAQKLVQAEREAQAslrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 796
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  797 EKeelseeiatlQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRhslatislEMERQKRDAQSRQEQDRSTVNAl 876
Cdd:PTZ00121  1603 EE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK--------EAEEKKKAEELKKAEEENKIKA- 1663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  877 tselrDLRAQLEEAVAAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQlrlledarDGLRRELLEAQRKLRESQEGREV 956
Cdd:PTZ00121  1664 -----AEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEEAKKA--------EELKKKEAEEKKKAEELKKAEEE 1727

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693  957 QRQEAGELRRSLGEGAKEREALRRSNEELRaavKKAESERISLKLANEDKEQKLALLEE 1015
Cdd:PTZ00121  1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---KIAHLKKEEEKKAEEIRKEKEAVIEE 1783
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1417-1754 1.61e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.61e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1417 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTE 1496
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1497 ALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQ 1576
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1577 QLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1656
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1657 EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA-----QQQQHLELQQEVERLRSAQVQ 1731
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGLAGAVAVLIGVEAA 535

                          330       340
                   ....*....|....*....|...
gi 1622834693 1732 TERTLEARERAHRQRVRGLEEQV 1754
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV 558
PTZ00121 PTZ00121
MAEBL; Provisional
 603-1193 1.17e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 83.65  E-value: 1.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  603 SRQLSGREQELEQARRAAQRQMEALERAAREKEAlaKERAGLAVQLAAAERegrtlSEEATRLRLEKEALEGSLFEVQRQ 682
Cdd:PTZ00121  1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEA--KKKAEDARKAEEARK-----AEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  683 LAqlEARREHLEAEGQALLLAKETltgelaglrQQIIAIQEKASLDKELMAQKLVQAER-EAQASLREQRAAHEED-LQR 760
Cdd:PTZ00121  1160 AE--DARKAEEARKAEDAKKAEAA---------RKAEEVRKAEELRKAEDARKAEAARKaEEERKAEEARKAEDAKkAEA 1228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  761 LQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEglLLAESEKQQALSLKESEKTALSEK 840
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADEAKKAEEKKKADE 1306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  841 LMGtrhslatiSLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVA---AHAQEVRRLQEQAQDLGKQRDSCLR 917
Cdd:PTZ00121  1307 AKK--------KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAeaeAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  918 EAEELRTQLRLLEDArDGLRRELLEAQRKLRESQEgREVQRQEAGELRRSLGEGAKEREALRRSNEELRA--AVKKAESE 995
Cdd:PTZ00121  1379 KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKK-AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  996 RISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL--AELQGRL 1073
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkAEEAKKA 1536

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1074 ALGERAEKESRRETLGLRQRLLKGEaslevmrQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELK 1153
Cdd:PTZ00121  1537 DEAKKAEEKKKADELKKAEELKKAE-------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622834693 1154 LEATRAEAAEL-GLRLSAAEGRAQGLEAELARVEAQRRAAE 1193
Cdd:PTZ00121  1610 EEAKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 313-1137 2.51e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 2.51e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  313 GTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ-------VAQQQAEEL 385
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQakkaleyYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  386 RQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 465
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  466 KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATV 545
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  546 AREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQME 625
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  626 ALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKE 705
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  706 TLTGELAGLRQQIIAIQEKASLDKE--------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERA 777
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQKLvraltelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  778 QLQSQLQREQEELLARLEAEKEELSEEIATLQQERdeglLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 857
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEE----GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  858 QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLR 937
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  938 RELLEAQRKLRESQEGREVQRQEagELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEAR 1017
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQE--EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1018 TAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETlgLRQRLLKG 1097
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE--EAEILLKY 933

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622834693 1098 EASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1137
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
PTZ00121 PTZ00121
MAEBL; Provisional
 970-1740 5.32e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 5.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  970 EGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagELRTGLQEVERSRLEARRELQELR 1049
Cdd:PTZ00121  1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAK--------KTETGKAEEARKAEEAKKKAEDAR 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1050 RQMKMLDSENTRLGREL--AELQGRLALGERAEKESRRETLGLRQRLLKGEAS---LEVMR-QELQVAQRKLQEQEGEFR 1123
Cdd:PTZ00121  1129 KAEEARKAEDARKAEEArkAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkaEEVRKaEELRKAEDARKAEAARKA 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1124 TRERRLlgslEEARGTEKQQLDHA--RGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGglrS 1201
Cdd:PTZ00121  1209 EEERKA----EEARKAEDAKKAEAvkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA---D 1281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1202 ALRRGLGLGRAPspaprpvpgspardaaaggsgdglsspsnlECSPGSQPPSPGPATSPAPPDLDPETVRGALQEFLQEL 1281
Cdd:PTZ00121  1282 ELKKAEEKKKAD------------------------------EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1282 RSAQRERDDLRTQTSAlshQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGrlSGVQAEMALQEESVRRSERERRAT 1361
Cdd:PTZ00121  1332 DAAKKKAEEAKKAAEA---AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEAKKKAEEDKKK 1406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1362 LDQIATLERSLQATESELRASQEKiskMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQ 1441
Cdd:PTZ00121  1407 ADELKKAAAAKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1442 aqalqdRVDSLQRQVADSEVKAGTLQLTVERLNGA--LAKVEESEGAlrDKVRGLTEALAQSSASLNSTQDKNLHLQKA- 1518
Cdd:PTZ00121  1484 ------KADEAKKKAEEAKKKADEAKKAAEAKKKAdeAKKAEEAKKA--DEAKKAEEAKKADEAKKAEEKKKADELKKAe 1555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1519 -LTACEHDRQVLQ-----ERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAA 1592
Cdd:PTZ00121  1556 eLKKAEEKKKAEEakkaeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1593 LHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRT 1672
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693 1673 LTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARE 1740
Cdd:PTZ00121  1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 482-1172 2.20e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 2.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  482 ELELSMTKLRAEEASLQDSlSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELrleqe 561
Cdd:pfam12128  257 ELRLSHLHFGYKSDETLIA-SRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQ----- 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  562 vARQGLEGSLRVAEQAQEvleqQLPTLRHERSRLQEQLAQLSRQLSGREQELEqaRRAAQRQMEALERAAREKEALAKER 641
Cdd:pfam12128  331 -HGAFLDADIETAAADQE----QLPSWQSELENLEERLKALTGKHQDVTAKYN--RRRSKIKEQNNRDIAGIKDKLAKIR 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  642 AGLAVQLAAAEREGRTLSEEAtrlrleKEALEGSLFEVQRQLAQLEARREHLEaegqaLLLAKETLTGElagLRQQIIAI 721
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRLGELK-----LRLNQATATPE---LLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKasLDKELMAQKLVQAERE-AQASLREQRAAHEEDLQRLQREkEAAWRELEAERAQLQSQLQREQEELLARLEAEKEE 800
Cdd:pfam12128  470 DER--IERAREEQEAANAEVErLQSELRQARKRRDQASEALRQA-SRRLEERQSALDELELQLFPQAGTLLHFLRKEAPD 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  801 LSEEIATLqqerdeglllaeseKQQALSLKESEKTALSEKLMGTRHSLATISLEMERqkrdaqsrqeQDRSTVNALTSEL 880
Cdd:pfam12128  547 WEQSIGKV--------------ISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKR----------IDVPEWAASEEEL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  881 RDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQlrlLEDARDGLRRELLEAQRKLRESQEGREVQRQE 960
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTA---LKNARLDLRRLFDEKQSEKDKKNKALAERKDS 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  961 AGELRRSLgegAKEREALRRSNEELRAAVKKAESErislklANEDKEQKLALLEEARTAvgkeagELRTGLQEVERSRLE 1040
Cdd:pfam12128  680 ANERLNSL---EAQLKQLDKKHQAWLEEQKEQKRE------ARTEKQAYWQVVEGALDA------QLALLKAAIAARRSG 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1041 ARRELQELRRQMKM------LDSEN-TRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQR 1113
Cdd:pfam12128  745 AKAELKALETWYKRdlaslgVDPDViAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1114 KLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAE 1172
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQ 883
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1518-1738 2.91e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1518 ALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQ 1597
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1598 KLQDERRLLQERLGSLQRALAQLEAEKR-----------EVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK 1666
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPlalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1667 GRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1738
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1274-1613 8.49e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.20  E-value: 8.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1274 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1353
Cdd:pfam07888   47 LQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1354 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESrtvklelQRRSLEGELQRSRL 1433
Cdd:pfam07888  127 HEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE-------ELRSLSKEFQELRN 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1434 GLSDREAQAQALQDRVDSL-------QRQVADSEVKAGTLQLTVERLNGALAKVE------ESEGALRDKVRG-LTEALA 1499
Cdd:pfam07888  200 SLAQRDTQVLQLQDTITTLtqklttaHRKEAENEALLEELRSLQERLNASERKVEglgeelSSMAAQRDRTQAeLHQARL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1500 QSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLE-----------LQQ 1568
Cdd:pfam07888  280 QAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEvelgrekdcnrVQL 359

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1622834693 1569 VEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSL 1613
Cdd:pfam07888  360 SESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETV 404
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 307-622 4.02e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 45.60  E-value: 4.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  307 ASQDLLGTLRKQLSDSESERRALEEQlqrlrdktdgaMQAQEDAQRevqrlrsanelLSREKSNLAHSLQVAQQQAEELR 386
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADK-----------ERAEADRQR-----------LEQEKQQQLAAISGSQSQLESTD 1596

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  387 QereklQAAQEELRRQRDRLEEEQEDavqdgarVRRELERSHRQLEQLEGK-----------RSVLAKELVE-VREALSR 454
Cdd:NF012221  1597 Q-----NALETNGQAQRDAILEESRA-------VTKELTTLAQGLDALDSQatyagesgdqwRNPFAGGLLDrVQEQLDD 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  455 ATLQ--------RDMLQAEKAEVAEALTKAEAGRVELElsmtKLRAEeasLQDSLSKLSALNESLAQDKLDlNRLVAQLE 526
Cdd:NF012221  1665 AKKIsgkqladaKQRHVDNQQKVKDAVAKSEAGVAQGE----QNQAN---AEQDIDDAKADAEKRKDDALA-KQNEAQQA 1736

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  527 EEKA--ALQGRQRQAEQEATVAREEQERLEELRLEQEVA------RQGLEGSlRVAEQAQEVlEQQLPTLRHERSRLQEQ 598
Cdd:NF012221  1737 ESDAnaAANDAQSRGEQDASAAENKANQAQADAKGAKQDesdkpnRQGAAGS-GLSGKAYSV-EGVAEPGSHINPDSPAA 1814

                          330       340
                   ....*....|....*....|....*.
gi 1622834693  599 L-AQLSRQLSGREQE-LEQARRAAQR 622
Cdd:NF012221  1815 AdGRFSEGLTEQEQEaLEGATNAVNR 1840
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 293-820 3.28e-28

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 124.28  E-value: 3.28e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  293 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 372
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  373 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 452
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  453 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAAL 532
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  533 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLeqQLPTLRHERSRLQEQLAQLSRQLSGREQE 612
Cdd:COG1196    462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  613 LEQA--RRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARR 690
Cdd:COG1196    540 LEAAlaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  691 EHLEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAA 768
Cdd:COG1196    620 DTLLGRtlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834693  769 WRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAE 820
Cdd:COG1196    700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 376-1196 5.19e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 120.55  E-value: 5.19e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  376 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrreLERSHRQLEQLEgkRSVLAKELVEVREALSRA 455
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAER--------YKELKAELRELE--LALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  456 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGR 535
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  536 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQ 615
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  616 ARRAAQRQMEALERAAREKEALAKERAglAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLE- 694
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEr 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  695 --AEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELM--AQKLVQAEREAQASLreqRAAHEEDLQRLQREKEAAWR 770
Cdd:TIGR02168  483 elAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvLSELISVDEGYEAAI---EAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  771 elEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLL----AESEKQQALS-------LKESEKTALsE 839
Cdd:TIGR02168  560 --KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkFDPKLRKALSyllggvlVVDDLDNAL-E 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  840 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL--TSELRDLRAQLEEavaahaqevrrLQEQAQDLGKQRDSCLR 917
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEE-----------LEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  918 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI 997
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  998 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1077
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1078 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAT 1157
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK-RSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1622834693 1158 RAEAAELGLRlsAAEGRAQGLEAELARVEAQRRAAEAQL 1196
Cdd:TIGR02168  945 LSEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 326-1117 1.41e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 119.01  E-value: 1.41e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  326 RRALEEQLQRLRDKTDGAMQAQE--DAQREVQRLRSANELLS--REKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 401
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKElkAELRELELALLVLRLEElrEELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  402 QRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRV 481
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  482 ELELSMTKLRAEeasLQDSLSKLSALNESLaqdkLDLNRLVAQLEEEKAALQGRQRQAEQ-----EATVAREEQERLEEL 556
Cdd:TIGR02168  355 SLEAELEELEAE---LEELESRLEELEEQL----ETLRSKVAQLELQIASLNNEIERLEArlerlEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  557 RLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQAR---RAAQRQMEALERAARE 633
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEG 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  634 KEALAKERAGL-------------------AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLE 694
Cdd:TIGR02168  508 VKALLKNQSGLsgilgvlselisvdegyeaAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  695 AEGQALLLAKETLTGELAGLRQQIIAIQEKAS--LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQRekeaaWREL 772
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSylLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG-----GVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  773 EAERAQLQSQLQREQEellarleaekeelseeIATLQQERDEgLLLAESEKQQALSLKESEKTALSEKLmgtrHSLATIS 852
Cdd:TIGR02168  663 GGSAKTNSSILERRRE----------------IEELEEKIEE-LEEKIAELEKALAELRKELEELEEEL----EQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  853 LEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAvaahAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDA 932
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL----EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  933 RDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL 1012
Cdd:TIGR02168  798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1013 LEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA-LGERAEKESRRETLGLR 1091
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEAE 957

                          810       820
                   ....*....|....*....|....*.
gi 1622834693 1092 QRLLKGEASLEVMRQELQVAQRKLQE 1117
Cdd:TIGR02168  958 ALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 581-1137 1.77e-26

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 118.50  E-value: 1.77e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  581 LEQQLPTLRHERSRlqeqlAQLSRQLSGREQELEQARRAAQRQ--MEALERAAREKEALAKERAGLAVQLAAAEREGRTL 658
Cdd:COG1196    198 LERQLEPLERQAEK-----AERYRELKEELKELEAELLLLKLRelEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  659 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEK--ASLDKELMAQKL 736
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEleELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  737 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE---------ELLARLEAEKEELSEEIAT 807
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  808 LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL 887
Cdd:COG1196    433 LEEEEEE-EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  888 EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL-----RESQEGREVQRQEAG 962
Cdd:COG1196    512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratfLPLDKIRARAALAAA 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  963 ELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEAR 1042
Cdd:COG1196    592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1043 RELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEF 1122
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570
                   ....*....|....*
gi 1622834693 1123 RTRERRLLGSLEEAR 1137
Cdd:COG1196    752 ALEELPEPPDLEELE 766
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 293-1073 6.60e-26

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 117.08  E-value: 6.60e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  293 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLA 372
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  373 HSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQedavqdgARVRRELErshRQLEQLEGKRSVLAKELVEVREAL 452
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEEL-------AELEEKLE---ELKEELESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  453 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLA-QDKLDLNRLVAQLEEEKAA 531
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  532 LQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLE---QQLPTLRHERSRLQEQLAQLSRQLSG 608
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsEGVKALLKNQSGLSGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  609 REqELEQARRAAQRQ------MEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQ 682
Cdd:TIGR02168  532 DE-GYEAAIEAALGGrlqavvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  683 LAQLEARREHL-------EAEGQALLLAKE--------TLTGELA--------GLRQQIIAIQEKASLDKELMAQKLVQA 739
Cdd:TIGR02168  611 DPKLRKALSYLlggvlvvDDLDNALELAKKlrpgyrivTLDGDLVrpggvitgGSAKTNSSILERRREIEELEEKIEELE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  740 EREAQasLREQRAAHEEDLQRLQREKEAAWRELEAERAQLqsqlqREQEELLARLEAEKEELSEEIATLQQERDEglLLA 819
Cdd:TIGR02168  691 EKIAE--LEKALAELRKELEELEEELEQLRKELEELSRQI-----SALRKDLARLEAEVEQLEERIAQLSKELTE--LEA 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  820 ESEKQQALSLKESEKTALSEKLMGTRhslatislemERQKRDAQSRQEQDRSTVNALTSELRDLR---AQLEEAVAAHAQ 896
Cdd:TIGR02168  762 EIEELEERLEEAEEELAEAEAEIEEL----------EAQIEQLKEELKALREALDELRAELTLLNeeaANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  897 EVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKERE 976
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  977 ALRRSNEELRAAVKKAESERISLKLanedkeQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLD 1056
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLEV------RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985

                          810
                   ....*....|....*..
gi 1622834693 1057 SENTRLGRELAELQGRL 1073
Cdd:TIGR02168  986 PVNLAAIEEYEELKERY 1002
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 397-996 1.65e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 115.42  E-value: 1.65e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  397 EELRRQRDRLEEEQEDAVQdGARVRRELERshRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 476
Cdd:COG1196    196 GELERQLEPLERQAEKAER-YRELKEELKE--LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  477 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEatvareeqerLEEL 556
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE----------LEEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  557 RLEQEVA---RQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAARE 633
Cdd:COG1196    343 EEELEEAeeeLEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  634 KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAG 713
Cdd:COG1196    423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  714 LRQQIIAIQEKASLDKELMAQKLVQAEREAQAslREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELlaR 793
Cdd:COG1196    503 YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEA--AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--P 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  794 LEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 873
Cdd:COG1196    579 LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  874 NALTSELRDLRAQLEEAVAAhaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEG 953
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAE-----AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1622834693  954 REVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 996
Cdd:COG1196    734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
1-95 2.99e-25

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 104.74  E-value: 2.99e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693    1 MLREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFT 80
Cdd:pfam15035   96 LLREQLEQASRANEALREDLQKLTNDWERAREELEQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTAT 175

                           90
                   ....*....|....*
gi 1622834693   81 ERDLLQLGGELARTS 95
Cdd:pfam15035  176 ERDLSELKTEFSRTS 190
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 309-910 7.43e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 113.11  E-value: 7.43e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  309 QDLLGTLRKQLSDSESERRALEE--QLQRLRDKTDGAMQAQEDAQREVQRlrsanELLSREKSNLAHSLQVAQQQAEELR 386
Cdd:COG1196    192 EDILGELERQLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAEL-----EELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  387 QEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEK 466
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  467 AEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVA 546
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  547 REEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsGREQELEQARRAAQRQMEA 626
Cdd:COG1196    427 EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  627 LERAAREKEALAKERagLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKET 706
Cdd:COG1196    506 FLEGVKAALLLAGLR--GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  707 LTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 786
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  787 QEELLARLEAEKEelseeiATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQ 866
Cdd:COG1196    664 GGSRRELLAALLE------AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1622834693  867 EQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGK 910
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 817-1620 2.46e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 111.69  E-value: 2.46e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  817 LLAESEKQQALSLKESEKT----ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD-RSTVNALTSELRDLRAQLEEAV 891
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEaEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  892 AAHaqevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 971
Cdd:TIGR02168  274 LEV----SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  972 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR- 1050
Cdd:TIGR02168  350 KEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKk 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1051 ----QMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1126
Cdd:TIGR02168  430 leeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1127 RRLLGSLEEA--RGTEKQQLDHARGLELKLEATraeaaeLGLRLSAAEGRaqGLEAELARVEAQR-----RAAEAQLGGL 1199
Cdd:TIGR02168  510 ALLKNQSGLSgiLGVLSELISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKqnelgRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1200 RSALRRGLGLGRAPS------PAPRPVPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAppdLDPETVR-- 1271
Cdd:TIGR02168  582 KGTEIQGNDREILKNiegflgVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVT---LDGDLVRpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1272 ----GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlrarQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1347
Cdd:TIGR02168  659 gvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-------ELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1348 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1427
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1428 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSsaslns 1507
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL------ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1508 tqdknlhlqkaltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQE 1587
Cdd:TIGR02168  886 ---------------EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1622834693 1588 GEA-AALHMVQKLQDERRLLQERLGSLQRALAQL 1620
Cdd:TIGR02168  951 LTLeEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 879-1690 8.06e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.15  E-value: 8.06e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  879 ELRDLRAQLEEA-VAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 957
Cdd:TIGR02168  214 RYKELKAELRELeLALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  958 RQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1037
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1038 RLEARRELQELRRqmkmldsentrlGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQvAQRKLQE 1117
Cdd:TIGR02168  374 LEELEEQLETLRS------------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-ELKELQA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1118 QEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAE---GRAQGLEAELARVEAQRRAAEA 1194
Cdd:TIGR02168  441 ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLErlqENLEGFSEGVKALLKNQSGLSG 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1195 QLGGLRSALRRGLGLGRApspaprpvpgspaRDAAAGGSGDGL---SSPSNLECSPGSQPPSPGPATSPAPPDLDPETVR 1271
Cdd:TIGR02168  521 ILGVLSELISVDEGYEAA-------------IEAALGGRLQAVvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1272 GALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARR-SVDGRLSGVQAEMALQEES 1350
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIvTLDGDLVRPGGVITGGSAK 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1351 VRRsererratldqiatlerSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQR 1430
Cdd:TIGR02168  668 TNS-----------------SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1431 SRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQD 1510
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1511 KNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEA 1590
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1591 AALHMVQKLQDERRLLQERLGSLQRALAQLEAekrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEkgrLD 1670
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSELRRELEELRE---KLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK---IE 964

                          810       820
                   ....*....|....*....|
gi 1622834693 1671 RTLTGAELELAEAQRQIQQL 1690
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 524-1204 3.05e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 3.05e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  524 QLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS 603
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  604 RQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQL 683
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  684 AQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQR 763
Cdd:TIGR02168  396 ASLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  764 EKEAAWRELEAERAQLQSQLQREqeELLARLEAEKEELSEEIATLQQERdEGLLLAESEKQQALSLKESEKTALSEKLMG 843
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQARL--DSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSELISVDEGYEAAIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  844 TRHSLATISLEMERQKRDAQSRQEQDRSTVNALTS-------ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCL 916
Cdd:TIGR02168  546 RLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgteiqGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  917 REAEELRTQLRLL------------------------------EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRR 966
Cdd:TIGR02168  626 LVVDDLDNALELAkklrpgyrivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  967 SLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQ 1046
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1047 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKL------QEQEG 1120
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1121 EFRTRERRLLGSLEEARGTEKQQLDHARgleLKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLR 1200
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLR---SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942


                   ....
gi 1622834693 1201 SALR 1204
Cdd:TIGR02168  943 ERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 823-1381 1.22e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 106.17  E-value: 1.22e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  823 KQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHA---QEVR 899
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArleQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  900 RLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALR 979
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  980 RSNEELRAAVKKAESERISLKLANEDKEQKLALLEEartavgkEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSEN 1059
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEE-------ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1060 TRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGT 1139
Cdd:COG1196    459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1140 EKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLeaELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRP 1219
Cdd:COG1196    539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL--PLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1220 VPGSPARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAPPDLDPETVRGALQEFLQELRSAQRERDDLRTQTSALS 1299
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1300 HQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESEL 1379
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ..
gi 1622834693 1380 RA 1381
Cdd:COG1196    777 EA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 755-1521 3.18e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 101.67  E-value: 3.18e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  755 EEDLQRLQREKEAA--WRELEAERAQLQSQLQ----REQEELLARLEAEKEELSEEIATLQQErdeglllaESEKQQALS 828
Cdd:TIGR02168  199 ERQLKSLERQAEKAerYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAE--------LQELEEKLE 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  829 LKESEKTALSEK---LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAvaahAQEVRRLQEQA 905
Cdd:TIGR02168  271 ELRLEVSELEEEieeLQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL----AEELAELEEKL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  906 QDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEEL 985
Cdd:TIGR02168  347 EELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  986 RAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeageLRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRE 1065
Cdd:TIGR02168  427 LKKLEEAELKELQAELEELEEELEELQEELER---------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1066 LAELQGrLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK-LQEQEGEFRTRERRLLGSLEEARgtekqqL 1144
Cdd:TIGR02168  498 QENLEG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNE------L 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1145 DHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSA--LRRGLGLGRAPSPAPRPVPG 1222
Cdd:TIGR02168  571 GRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVddLDNALELAKKLRPGYRIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1223 SP----ARDAAAGGSGDGLSSPSNLECSPGSQPPSPGPATSPAPPDLDP-ETVRGALQEFLQELRSAQRERDDLRTQTSA 1297
Cdd:TIGR02168  651 DGdlvrPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKAlAELRKELEELEEELEQLRKELEELSRQISA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1298 LSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERerratldQIATLERSLQATES 1377
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA-------QIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1378 ELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVA 1457
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834693 1458 DSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTA 1521
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE 947
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 942-1754 9.33e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 9.33e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  942 EAQRKLRESQEGREVQRQEAGELRR---SLGEGAKEREALRRSNEELRAAvkkaesERISLKLANEDKEQKLALLEEART 1018
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERqlkSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1019 AVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGE 1098
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1099 ASLEVMRQELQVAQRKLQEQEGEFRtrerRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGL 1178
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1179 EAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgsPARDAAAGGSGDGLSSPSNLECSPgsqppspgpat 1258
Cdd:TIGR02168  406 EARLERLEDRRERLQQEIEELLKKLEE------------------AELKELQAELEELEEELEELQEEL----------- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1259 spappdldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDhatlRARQLQKAVAESEEARRSVDGRLS 1338
Cdd:TIGR02168  457 ---------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----NLEGFSEGVKALLKNQSGLSGILG 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1339 GVQA------------EMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEV 1406
Cdd:TIGR02168  524 VLSElisvdegyeaaiEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1407 LDASESRTVKLelqRRSLEGELQRSRLglSDREAQAQALQDRVDSLQRQVadseVKAGTLQLTVERLNGALAKVEESEGA 1486
Cdd:TIGR02168  604 AKDLVKFDPKL---RKALSYLLGGVLV--VDDLDNALELAKKLRPGYRIV----TLDGDLVRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1487 LRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1566
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1567 QQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLD 1646
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1647 KVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLR 1726
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          810       820
                   ....*....|....*....|....*...
gi 1622834693 1727 sAQVQTERTLEARERAHRQRVRGLEEQV 1754
Cdd:TIGR02168  915 -RELEELREKLAQLELRLEGLEVRIDNL 941
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 856-1457 4.01e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.62  E-value: 4.01e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  856 ERQKRDAQS----RQEQDRSTVNALTSELRDLRAQLEEA---VAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRL 928
Cdd:COG1196    206 ERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELeaeLEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  929 LEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQ 1008
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1009 KLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETL 1088
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1089 GLRQRLLKGEASLEVMRQELQVAQRKLQEQEgefrTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRL 1168
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLE----AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1169 SAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRApspaprpvpgspARDAAAGgsgdglsspsnlecspg 1248
Cdd:COG1196    522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY------------LKAAKAG----------------- 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1249 sqPPSPGPATSPAPPDLDPETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAER-DHATLRARQLQKAVAESE 1327
Cdd:COG1196    573 --RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARlEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1328 EARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVL 1407
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1408 DASESRTVKLELQrrsLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVA 1457
Cdd:COG1196    731 EAEREELLEELLE---EEELLEEEALEELPEPPDLEELERELERLEREIE 777
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 380-1146 1.16e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 93.21  E-value: 1.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  380 QQAEELRQEREKLQAAQEELRRQRDR----LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRA 455
Cdd:TIGR02169  198 QQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  456 TLQRDML--------QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEE 527
Cdd:TIGR02169  278 NKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  528 EKAALQGRQRQAEQEAtvareeqerleelrleqevarQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLS 607
Cdd:TIGR02169  358 EYAELKEELEDLRAEL---------------------EEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  608 GREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 687
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  688 ARREHLEAEGQALLLAKETLTGELAGL-----------RQQIIAIQEKAS-------LDKELMAQKLVQAEREAQAS--- 746
Cdd:TIGR02169  497 AQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgERYATAIEVAAGnrlnnvvVEDDAVAKEAIELLKRRKAGrat 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  747 ---LREQRAAHEE--------------DLQRLQREKEAAWRELeaeraqLQSQLQREQEELLARLeaekeELSEEIATLq 809
Cdd:TIGR02169  577 flpLNKMRDERRDlsilsedgvigfavDLVEFDPKYEPAFKYV------FGDTLVVEDIEAARRL-----MGKYRMVTL- 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  810 qerdEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEE 889
Cdd:TIGR02169  645 ----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  890 avaahaqevrrLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLG 969
Cdd:TIGR02169  721 -----------IEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  970 EgaKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagelrtglqeversrlearrelQELR 1049
Cdd:TIGR02169  790 H--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI----------------------------QELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1050 RQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRL 1129
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ-IEKKRKR 918

                          810
                   ....*....|....*..
gi 1622834693 1130 LGSLEEARGTEKQQLDH 1146
Cdd:TIGR02169  919 LSELKAKLEALEEELSE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 722-1205 1.56e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 92.69  E-value: 1.56e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKASLDKELMAQKLVQAERE---AQASLREQRAAHEEdLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEK 798
Cdd:COG1196    220 EELKELEAELLLLKLRELEAEleeLEAELEELEAELEE-LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  799 EELSEEIatLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMErQKRDAQSRQEQDRSTVNALTS 878
Cdd:COG1196    299 RLEQDIA--RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE-EAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  879 ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR 958
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  959 QEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQK----LALLEEARTAVGKEAGELRTGLQEV 1034
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFlegvKAALLLAGLRGLAGAVAVLIGVEAA 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1035 ERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRqelqvaqrk 1114
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS--------- 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1115 LQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEA 1194
Cdd:COG1196    607 DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686

                          490
                   ....*....|.
gi 1622834693 1195 QLGGLRSALRR 1205
Cdd:COG1196    687 RLAEEELELEE 697
PTZ00121 PTZ00121
MAEBL; Provisional
 325-1015 2.66e-17

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 89.04  E-value: 2.66e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  325 ERRALEEQLQRLRDKTDGAMQAQEDAqREVQRLRSANELLSREKSNLAHSLQVAQQ--QAEELRQEREKLQAAQEELRRQ 402
Cdd:PTZ00121  1138 DARKAEEARKAEDAKRVEIARKAEDA-RKAEEARKAEDAKKAEAARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEE 1216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  403 RDRLEEEQE-DAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQrdmlqAEKAEVAEALTKAEAGRV 481
Cdd:PTZ00121  1217 ARKAEDAKKaEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK-----AEEARKADELKKAEEKKK 1291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  482 --ELELSMTKLRAEEASLQ-DSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRL 558
Cdd:PTZ00121  1292 adEAKKAEEKKKADEAKKKaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  559 EQEVARQGLEGSLRVAEQAQEVLEQQlptlrhERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALA 638
Cdd:PTZ00121  1372 KKEEAKKKADAAKKKAEEKKKADEAK------KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK 1445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  639 KERAGLAVQLAAAEREGRTLSEEATRL-RLEKEALEG-SLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQ 716
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKAdEAKKKAEEAkKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD 1525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  717 QIIAIQEKASLDKELMAQKLVQAEREAQAslrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 796
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  797 EKeelseeiatlQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRhslatislEMERQKRDAQSRQEQDRSTVNAl 876
Cdd:PTZ00121  1603 EE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKK--------EAEEKKKAEELKKAEEENKIKA- 1663

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  877 tselrDLRAQLEEAVAAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQlrlledarDGLRRELLEAQRKLRESQEGREV 956
Cdd:PTZ00121  1664 -----AEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEEAKKA--------EELKKKEAEEKKKAEELKKAEEE 1727

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693  957 QRQEAGELRRSLGEGAKEREALRRSNEELRaavKKAESERISLKLANEDKEQKLALLEE 1015
Cdd:PTZ00121  1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKK---KIAHLKKEEEKKAEEIRKEKEAVIEE 1783
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 368-707 4.84e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.80  E-value: 4.84e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  368 KSNLAHSLQVAQQQA-EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELV 446
Cdd:TIGR02168  664 GSAKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  447 EVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLE 526
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  527 EEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQL 606
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  607 SGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAA-AEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQ 685
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 1622834693  686 L--------------EARREHLEAEGQALLLAKETL 707
Cdd:TIGR02168  984 LgpvnlaaieeyeelKERYDFLTAQKEDLTEAKETL 1019
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 284-1018 9.07e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 87.05  E-value: 9.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  284 LALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESER--------RALEEQLQRLRDKTDGAMQAQEDAQREVQ 355
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqlrvkekiGELEAEIASLERSIAEKERELEDAEERLA 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  356 RLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLE 435
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  436 GKRSVLAKELVEVREALsratlqrdmlqaekAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDK 515
Cdd:TIGR02169  406 RELDRLQEELQRLSEEL--------------ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  516 LDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSL----RVAEQAQEVLEQQLPTLRHE 591
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVaqlgSVGERYATAIEVAAGNRLNN 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  592 RSRLQEQLAQLSRQLSGREQeleqARRAAQRQMEALERAAREKEALAKERA-GLAVQLAAAERE---------GRTLS-- 659
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKRRK----AGRATFLPLNKMRDERRDLSILSEDGViGFAVDLVEFDPKyepafkyvfGDTLVve 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  660 --EEATRL--RLEKEALEGSLFEVQ-------RQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASld 728
Cdd:TIGR02169  628 diEAARRLmgKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLD-- 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  729 kelmaqKLVQAEREAQASLREQRAaheeDLQRLQREKEAAWRELEAERAQLQSqLQREQEELLARLEAEKEELSEEIATL 808
Cdd:TIGR02169  706 ------ELSQELSDASRKIGEIEK----EIEQLEQEEEKLKERLEELEEDLSS-LEQEIENVKSELKELEARIEELEEDL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  809 QQERDEgllLAESEKQQALSlKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLE 888
Cdd:TIGR02169  775 HKLEEA---LNDLEARLSHS-RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  889 EavaahaqevrrLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL 968
Cdd:TIGR02169  851 S-----------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834693  969 GEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEART 1018
Cdd:TIGR02169  920 SELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1417-1754 1.61e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.61e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1417 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTE 1496
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1497 ALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQ 1576
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1577 QLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSH 1656
Cdd:COG1196    376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1657 EDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA-----QQQQHLELQQEVERLRSAQVQ 1731
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGLAGAVAVLIGVEAA 535

                          330       340
                   ....*....|....*....|...
gi 1622834693 1732 TERTLEARERAHRQRVRGLEEQV 1754
Cdd:COG1196    536 YEAALEAALAAALQNIVVEDDEV 558
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 557-1204 1.90e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 1.90e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  557 RLEQEVARQGLEGSLRVAEQAQEvLEQQLPTLRHERS-----RLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAA 631
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKE-LKAELRELELALLvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  632 REKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGEL 711
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  712 AGLRQQIIAIQEK--ASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEE 789
Cdd:TIGR02168  354 ESLEAELEELEAEleELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  790 LLARLEAEKEELSEEIATLqQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQK---------R 860
Cdd:TIGR02168  434 ELKELQAELEELEEELEEL-QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkalL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  861 DAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQ--EVRRLQEQAQDLGKQRDSCL-------------REAEELRTQ 925
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavVVENLNAAKKAIAFLKQNELgrvtflpldsikgTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  926 LRLLEDARDGLRRELLEAQRKLR--------------ESQEGREVQRQEAGELR--------------RSLGEGAKEREA 977
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvdDLDNALELAKKLRPGYRivtldgdlvrpggvITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  978 LRRSNE--ELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKML 1055
Cdd:TIGR02168  673 LERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1056 DSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEE 1135
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1136 ARGTEKQqldhARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALR 1204
Cdd:TIGR02168  833 IAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897
PTZ00121 PTZ00121
MAEBL; Provisional
 360-1044 2.31e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.96  E-value: 2.31e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  360 ANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ-----EELRRQRD--RLEEE---QEDAVQDGARVRRELERSHR 429
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEdarkaEEARKAEDarKAEEArkaEDAKRVEIARKAEDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  430 QLEQLEGKRSVLAKELVEVREAlsratlqRDMLQAEKAEVAEALTKAEAGRvelelsmtklRAEEASLQDSLSKLSALNE 509
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKA-------EELRKAEDARKAEAARKAEEER----------KAEEARKAEDAKKAEAVKK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  510 SLAQDKldlnrlvaQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEgsLRVAEQAQEVLEQQlptlR 589
Cdd:PTZ00121  1232 AEEAKK--------DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADEAK----K 1297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  590 HERSRLQEQL---AQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLR 666
Cdd:PTZ00121  1298 AEEKKKADEAkkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  667 LEKEALEGSLFEVQRQLaqlEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKElMAQKLVQAErEAQAS 746
Cdd:PTZ00121  1378 KKADAAKKKAEEKKKAD---EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKK-KAEEAKKAD-EAKKK 1452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  747 LREQRAAhEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELL-----ARLEAEKEELSEEIATLQQERDEGLLLAES 821
Cdd:PTZ00121  1453 AEEAKKA-EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKkkadeAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  822 EKQQALSLKESEKTALSEKLMGTRHslatISLEMERQKRDAQSRQEQDRSTVNALTSELRDL------------------ 883
Cdd:PTZ00121  1532 EAKKADEAKKAEEKKKADELKKAEE----LKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAeearieevmklyeeekkm 1607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  884 ---RAQLEEAVAAHAQEVRRLQE---QAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 957
Cdd:PTZ00121  1608 kaeEAKKAEEAKIKAEELKKAEEekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  958 RQEAGELRRSLGEGAKEREALRRSNEELRAA--VKKAESER-ISLKLANEDKEQKLALLEEARTAVGkEAGELRTGLQEV 1034
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAeeLKKAEEENkIKAEEAKKEAEEDKKKAEEAKKDEE-EKKKIAHLKKEE 1766

                          730
                   ....*....|
gi 1622834693 1035 ERSRLEARRE 1044
Cdd:PTZ00121  1767 EKKAEEIRKE 1776
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 942-1622 4.13e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 4.13e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  942 EAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEeLRAAVKKAESERISLKLanEDKEQKLALLEEARTAVG 1021
Cdd:COG1196    176 EAERKLEATEENLERLEDILGELERQLEPLERQAEKAERYRE-LKEELKELEAELLLLKL--RELEAELEELEAELEELE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1022 KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASL 1101
Cdd:COG1196    253 AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1102 EVMRQELQVAQRKLQEQEGEFRTRERRL---LGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGL 1178
Cdd:COG1196    333 EELEEELEELEEELEEAEEELEEAEAELaeaEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1179 EAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgspARDAAaggsgdglsspsnlecspgsqppspgpat 1258
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEE-------------------EEEAL----------------------------- 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1259 spappdldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLS 1338
Cdd:COG1196    445 ---------EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1339 GVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKIskmkanetklegdkRRLKEVLDASESRTVKLE 1418
Cdd:COG1196    516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------------EYLKAAKAGRATFLPLDK 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1419 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAgtlqLTVERLNGALAKVEESEGALRDKVRGLTEAL 1498
Cdd:COG1196    582 IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT----LVAARLEAALRRAVTLAGRLREVTLEGEGGS 657

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1499 AQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQL 1578
Cdd:COG1196    658 AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1622834693 1579 REVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEA 1622
Cdd:COG1196    738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1280-1753 8.86e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 8.86e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1280 ELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERR 1359
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1360 ATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDRE 1439
Cdd:COG1196    306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1440 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKAL 1519
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1520 TACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAD------------------------------------ 1563
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalllaglrglagavavligveaayeaaleaala 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1564 --LELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVAL 1641
Cdd:COG1196    546 aaLQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1642 RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQE 1721
Cdd:COG1196    626 TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1622834693 1722 VERLRSAQVQTERTLEARERAHRQRVRGLEEQ 1753
Cdd:COG1196    706 ERELAEAEEERLEEELEEEALEEQLEAEREEL 737
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1150-1738 1.06e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.45  E-value: 1.06e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1150 LELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgspARDAA 1229
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEE-------------------LRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1230 AggsgdglsspsNLECSPGSQPPSPGPATSpappdlDPETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAER 1309
Cdd:COG1196    277 E-----------ELELELEEAQAEEYELLA------ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1310 DHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKM 1389
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1390 KANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT 1469
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1470 VERLNGALAKVEES-----------EGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQ 1538
Cdd:COG1196    500 EADYEGFLEGVKAAlllaglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1539 ALSEARKQSSSLGEQVQTLRGeVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALA 1618
Cdd:COG1196    580 DKIRARAALAAALARGAIGAA-VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1619 QLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLE 1698
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1622834693 1699 QSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1738
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 603-1193 1.17e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 83.65  E-value: 1.17e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  603 SRQLSGREQELEQARRAAQRQMEALERAAREKEAlaKERAGLAVQLAAAERegrtlSEEATRLRLEKEALEGSLFEVQRQ 682
Cdd:PTZ00121  1087 NRADEATEEAFGKAEEAKKTETGKAEEARKAEEA--KKKAEDARKAEEARK-----AEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  683 LAqlEARREHLEAEGQALLLAKETltgelaglrQQIIAIQEKASLDKELMAQKLVQAER-EAQASLREQRAAHEED-LQR 760
Cdd:PTZ00121  1160 AE--DARKAEEARKAEDAKKAEAA---------RKAEEVRKAEELRKAEDARKAEAARKaEEERKAEEARKAEDAKkAEA 1228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  761 LQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEglLLAESEKQQALSLKESEKTALSEK 840
Cdd:PTZ00121  1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE--LKKAEEKKKADEAKKAEEKKKADE 1306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  841 LMGtrhslatiSLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVA---AHAQEVRRLQEQAQDLGKQRDSCLR 917
Cdd:PTZ00121  1307 AKK--------KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAeaeAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  918 EAEELRTQLRLLEDArDGLRRELLEAQRKLRESQEgREVQRQEAGELRRSLGEGAKEREALRRSNEELRA--AVKKAESE 995
Cdd:PTZ00121  1379 KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKK-AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEA 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  996 RISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL--AELQGRL 1073
Cdd:PTZ00121  1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkAEEAKKA 1536

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1074 ALGERAEKESRRETLGLRQRLLKGEaslevmrQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELK 1153
Cdd:PTZ00121  1537 DEAKKAEEKKKADELKKAEELKKAE-------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622834693 1154 LEATRAEAAEL-GLRLSAAEGRAQGLEAELARVEAQRRAAE 1193
Cdd:PTZ00121  1610 EEAKKAEEAKIkAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 756-1650 7.01e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.88  E-value: 7.01e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  756 EDLQRLQREKEAAWRELEaeraqLQSQLQ-REQEELLARLEAEKEElseeIATLQQERDEglllAESEKQQAlslkESEK 834
Cdd:TIGR02169  198 QQLERLRREREKAERYQA-----LLKEKReYEGYELLKEKEALERQ----KEAIERQLAS----LEEELEKL----TEEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  835 TALSEKLMGTRHSLATISLEMERQKRDaqsRQEQDRSTVNALTSElrdlRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDS 914
Cdd:TIGR02169  261 SELEKRLEEIEQLLEELNKKIKDLGEE---EQLRVKEKIGELEAE----IASLERSIAEKERELEDAEERLAKLEAEIDK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  915 CLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAV----- 989
Cdd:TIGR02169  334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELdrlqe 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  990 --KKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELA 1067
Cdd:TIGR02169  414 elQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELA 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1068 ELQGRLALGERAEKESRRETLGLRQRLlkgEASLEVMRQELQVaqrklqeqegefrtrERRLLGSLEEARGTEKQ----- 1142
Cdd:TIGR02169  494 EAEAQARASEERVRGGRAVEEVLKASI---QGVHGTVAQLGSV---------------GERYATAIEVAAGNRLNnvvve 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1143 -QLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAE-------LARVEAQRRAAEAQLGGLRSAL--------RRG 1206
Cdd:TIGR02169  556 dDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEdgvigfaVDLVEFDPKYEPAFKYVFGDTLvvedieaaRRL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1207 LGLGRAPSPAPRPVPGSPA----RDAAAGGSGDGLSSPSNLECSPGsqppspgpatspappdlDPETVRGALQEFLQELR 1282
Cdd:TIGR02169  636 MGKYRMVTLEGELFEKSGAmtggSRAPRGGILFSRSEPAELQRLRE-----------------RLEGLKRELSSLQSELR 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1283 SAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATL 1362
Cdd:TIGR02169  699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1363 DQIATLERSLqateselraSQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQrsrlglsDREAQA 1442
Cdd:TIGR02169  779 EALNDLEARL---------SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ-------ELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1443 QALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRgltEALAQSSASLNSTQDKNLHLQKAltac 1522
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD---ELEAQLRELERKIEELEAQIEKK---- 915

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1523 ehdrQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLElqQVEAEgqlqqlrevlRQRQEGEAAALHMVQKLQ-D 1601
Cdd:TIGR02169  916 ----RKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLE--DVQAE----------LQRVEEEIRALEPVNMLAiQ 979

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1602 ERRLLQERLGSLQRALAQLEAEKREV-ERSALRLEKDRVALRRTLDKVER 1650
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAIlERIEEYEKKKREVFMEAFEAINE 1029
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
315-790 1.54e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 79.31  E-value: 1.54e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  315 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSlqvaQQQAEELRQEREKLQA 394
Cdd:PRK02224   204 LHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDL----RETIAETEREREELAE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  395 AQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQ---------------- 458
Cdd:PRK02224   280 EVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEaeslredaddleerae 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  459 -----RDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQ 533
Cdd:PRK02224   360 elreeAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  534 GRQRQAEQeatvareeqerlEELRLEQEVARQGLEGSLRV-----AEQAQEVLEQQLPTLRHERSRLQ---EQLAQLSRQ 605
Cdd:PRK02224   440 ERVEEAEA------------LLEAGKCPECGQPVEGSPHVetieeDRERVEELEAELEDLEEEVEEVEerlERAEDLVEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  606 LSGREQELEQARRAAQRQMEALERAAREKEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQ 685
Cdd:PRK02224   508 EDRIERLEERREDLEELIAERRETIEEKRERAEELRE----RAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAE 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  686 LEARREHLEAEgQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKlvqAEREAQASLREQRAAHEEDLQRLQREK 765
Cdd:PRK02224   584 LKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDERRERLAEK---RERKRELEAEFDEARIEEAREDKERAE 659

                          490       500       510
                   ....*....|....*....|....*....|.
gi 1622834693  766 EA------AWRELEAERAQLQSQLQREQEEL 790
Cdd:PRK02224   660 EYleqveeKLDELREERDDLQAEIGAVENEL 690
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1025-1692 1.78e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1025 GELRTGLQEVERSRLEARReLQELRRQMKMLDSEntRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1104
Cdd:COG1196    196 GELERQLEPLERQAEKAER-YRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1105 RQELQVAQRKLQEQegefRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELAR 1184
Cdd:COG1196    273 RLELEELELELEEA----QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1185 VEAQRRAAEAQLgglrsalrrglglgrapspaprpvpgspardaaaggsgdglsspsnlecspgsqppspgpatspappd 1264
Cdd:COG1196    349 AEEELEEAEAEL-------------------------------------------------------------------- 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1265 ldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEM 1344
Cdd:COG1196    361 ---AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1345 ALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASE--SRTVKLELQRR 1422
Cdd:COG1196    438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgfLEGVKAALLLA 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1423 SLEGELQRSRLGLSDREAQAQALQDR--VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQ 1500
Cdd:COG1196    518 GLRGLAGAVAVLIGVEAAYEAALEAAlaAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1501 SSASLNSTQDknlhlQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLRE 1580
Cdd:COG1196    598 GAAVDLVASD-----LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1581 VLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLdkvEREKLRSHEDTV 1660
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL---LEELLEEEELLE 749

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1622834693 1661 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEA 1692
Cdd:COG1196    750 EEALEELPEPPDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 288-641 3.14e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 3.14e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  288 HSALHKRQlQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSRE 367
Cdd:TIGR02168  670 SSILERRR-EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  368 KSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE 447
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  448 VREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEE 527
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  528 EKAAL-QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLS--- 603
Cdd:TIGR02168  909 KRSELrRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGpvn 988

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1622834693  604 -------RQLSGREQELEQARRAAQRQMEALERAAREKEALAKER 641
Cdd:TIGR02168  989 laaieeyEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 55-695 1.58e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 1.58e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693   55 EHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTgLRLAESRTEAALEKQALLQAQLEEQL 134
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-LELELEEAQAEEYELLAELARLEQDI 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  135 RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALEtedgeglqq 214
Cdd:COG1196    305 ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA--------- 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  215 tlrdlaqavlsdsesgvqlsgsertadasdgslrglsgqrtpspprrsspgrgrsprrgpspacsdsstlALIHSALHKR 294
Cdd:COG1196    376 ----------------------------------------------------------------------EAEEELEELA 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  295 QLQVQDMRGRYEASQDLLGtLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHS 374
Cdd:COG1196    386 EELLEALRAAAELAAQLEE-LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  375 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGK--RSVLAKELVEVREAL 452
Cdd:COG1196    465 LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAvlIGVEAAYEAALEAAL 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  453 SRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEkaAL 532
Cdd:COG1196    545 AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD--TL 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  533 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQqlptLRHERSRLQEQLAQLSRQLSGREQE 612
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA----LLEAEAELEELAERLAEEELELEEA 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  613 LEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREH 692
Cdd:COG1196    699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778


                   ...
gi 1622834693  693 LEA 695
Cdd:COG1196    779 LGP 781
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 831-1628 5.45e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 5.45e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  831 ESEKTALSEKLMGTRHSLATISLeMERQKRDAQSRQEQDRSTvnalTSELRDLRAQLEE-AVAAHAQEVRRLQEQAQDLG 909
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDL-IIDEKRQQLERLRREREK----AERYQALLKEKREyEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  910 KQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQrqeageLRRSLGEGAKEREALRRSNEELRAAV 989
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR------VKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  990 KKAESERISLKlanEDKEQKLALLEEARTAVGKEAGELRTGLQEVErsrlEARRELQELRRQMKMLDSENTRLGRELAEL 1069
Cdd:TIGR02169  318 EDAEERLAKLE---AEIDKLLAEIEELEREIEEERKRRDKLTEEYA----ELKEELEDLRAELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1070 QGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEqegeFRTRERRLLGSLEEARGTEKQQLDHARG 1149
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE----LEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1150 LELKLEATRAEAAELGLRLSAaegraqgLEAELARVEAQRRAAEAQLGGLRSA---LRRGLG-----LGRAPSPAPRPVP 1221
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSK-------LQRELAEAEAQARASEERVRGGRAVeevLKASIQgvhgtVAQLGSVGERYAT 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1222 gspARDAAAGGSGDGLSSPSNL---ECSPGSQPPSPGPAT-------SPAPPDLDPETVRGA------LQEFLQELRSAQ 1285
Cdd:TIGR02169  540 ---AIEVAAGNRLNNVVVEDDAvakEAIELLKRRKAGRATflplnkmRDERRDLSILSEDGVigfavdLVEFDPKYEPAF 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1286 RE--RDDLRTQtsalshqlaEMEAERDH------ATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESvrrsere 1357
Cdd:TIGR02169  617 KYvfGDTLVVE---------DIEAARRLmgkyrmVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLR------- 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1358 rratlDQIATLERSLQATESELR--------------ASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS 1423
Cdd:TIGR02169  681 -----ERLEGLKRELSSLQSELRrienrldelsqelsDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN 755

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1424 LEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKagtlqltverlngalaKVEESEGALRDKVRGLTEALAQSSA 1503
Cdd:TIGR02169  756 VKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP----------------EIQAELSKLEEEVSRIEARLREIEQ 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1504 SLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLR 1583
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLR 899

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 1622834693 1584 QRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVE 1628
Cdd:TIGR02169  900 ELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
443-1074 2.21e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 72.64  E-value: 2.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  443 KELVEVREALSRATLQRDMLQAEKaEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLsklsalnesLAQDKLDLNRLV 522
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIR-ELAERYAAARERLAELEYLRAALRLWFAQRRLEL---------LEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  523 AQLEEEKAALQGRQRQAEQEATVAREeqerleelrleqevARQGLEGS-LRVAEQAQEVLEQQLPTLRHERSRLQEQLAQ 601
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEA--------------QIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  602 LSRQLSGREQELEQARRAAQrqmEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQR 681
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAA---ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  682 QLAQ---------------LEARREHLEAE--------GQALLLA--------------KETLTGELAGLR-QQIIAIQE 723
Cdd:COG4913    448 ALAEalgldeaelpfvgelIEVRPEEERWRgaiervlgGFALTLLvppehyaaalrwvnRLHLRGRLVYERvRTGLPDPE 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  724 KASLDKELMAQKLVQAEREAQASLREQ--------RAAHEEDLQRLQR---------EKEAAWRELEAERAQLQSQLQRE 786
Cdd:COG4913    528 RPRLDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvCVDSPEELRRHPRaitragqvkGNGTRHEKDDRRRIRSRYVLGFD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  787 QEELLARLEAEKEELSEEIATLQQERDEglllaesekqqalslkesektalseklmgtrhsLATISLEMERQKRDAQSRQ 866
Cdd:COG4913    608 NRAKLAALEAELAELEEELAEAEERLEA---------------------------------LEAELDALQERREALQRLA 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  867 EQDRSTVN--ALTSELRDLRAQLEEAVAAHAqEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ 944
Cdd:COG4913    655 EYSWDEIDvaSAEREIAELEAELERLDASSD-DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  945 RKLRE-SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISL-KLANEDKEQKLALLEEARTAVGk 1022
Cdd:COG4913    734 DRLEAaEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAETADLDADLE- 812

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1023 EAGELRTGLQEVERSRLEARRElqelrrqmKMLDSENTRLGRELAELQGRLA 1074
Cdd:COG4913    813 SLPEYLALLDRLEEDGLPEYEE--------RFKELLNENSIEFVADLLSKLR 856
PTZ00121 PTZ00121
MAEBL; Provisional
 609-1194 2.75e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.48  E-value: 2.75e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  609 REQELEQARRAaqRQMEALERAAREKEALAKERAGLAVQLAAAER--EGRTLSEEATRLRLEKEALEGSLFEVQRqLAQL 686
Cdd:PTZ00121  1189 KAEELRKAEDA--RKAEAARKAEEERKAEEARKAEDAKKAEAVKKaeEAKKDAEEAKKAEEERNNEEIRKFEEAR-MAHF 1265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  687 EARREHLEAE----GQALLLAKETLTGELAGLRQQIIAIQE---KASLDK--ELMAQKLVQAEREAQASLREQRAAHEED 757
Cdd:PTZ00121  1266 ARRQAAIKAEearkADELKKAEEKKKADEAKKAEEKKKADEakkKAEEAKkaDEAKKKAEEAKKKADAAKKKAEEAKKAA 1345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  758 LQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESE--KT 835
Cdd:PTZ00121  1346 EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADeaKK 1425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  836 ALSEKlmgTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSC 915
Cdd:PTZ00121  1426 KAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  916 LREAEELRT--QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQE----AGELRRS--LGEGAKEREALRRSNEELRA 987
Cdd:PTZ00121  1503 KKAAEAKKKadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADelkkAEELKKAeeKKKAEEAKKAEEDKNMALRK 1582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  988 A--VKKAESERIS--LKLANEDKEQKLALL---EEARTAVG--KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSE 1058
Cdd:PTZ00121  1583 AeeAKKAEEARIEevMKLYEEEKKMKAEEAkkaEEAKIKAEelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1059 NTRLGRELAELQGRLALGERAEKESRRetlglrqrllKGEASLEVMRQELQVAQRKLQEQEgefrtrERRllgSLEEARG 1138
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKK----------AAEALKKEAEEAKKAEELKKKEAE------EKK---KAEELKK 1723

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834693 1139 TEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEA 1194
Cdd:PTZ00121  1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
297-790 3.40e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 71.87  E-value: 3.40e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  297 QVQDMRGRYEASQDLLGTLRKQLsdsESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ 376
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQI---ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  377 VAQQQAEELRQEREKLQAAQEELRRQR--------DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 448
Cdd:COG4913    306 RLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  449 REALSRAtlqRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ--------DSLSKLSALNESLAQDKLDLnR 520
Cdd:COG4913    386 RAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLErrksnipaRLLALRDALAEALGLDEAEL-P 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  521 LVAQL----EEEKA-------ALQGRQR----QAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEqQL 585
Cdd:COG4913    462 FVGELievrPEEERwrgaierVLGGFALtllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAG-KL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  586 PTLRHE-RSRLQEQLAQL-SRQLSGREQELEQARRAAQRQ-MEALERAAREK--------------------EALAKERA 642
Cdd:COG4913    541 DFKPHPfRAWLEAELGRRfDYVCVDSPEELRRHPRAITRAgQVKGNGTRHEKddrrrirsryvlgfdnraklAALEAELA 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  643 GLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLF---------EVQRQLAQLEARREHLEAEGQALLLAKE-------- 705
Cdd:COG4913    621 ELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvaSAEREIAELEAELERLDASSDDLAALEEqleeleae 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  706 --TLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREK--EAAWRELEAERAQLQS 781
Cdd:COG4913    701 leELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAveRELRENLEERIDALRA 780


                   ....*....
gi 1622834693  782 QLQREQEEL 790
Cdd:COG4913    781 RLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
293-775 5.98e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 71.10  E-value: 5.98e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  293 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQ--------EDAQREVQRLRSANELL 364
Cdd:COG4913    278 RAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnggdrlEQLEREIERLERELEER 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  365 SREKSNLAHSLQVAQQQ----AEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSV 440
Cdd:COG4913    358 ERRRARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  441 LAKELVEVREALSRAtlqrdmLQAEKAE---VAEALTKAEAGR-----VELELSMTKLR--AEEASLQDSLS-------- 502
Cdd:COG4913    438 IPARLLALRDALAEA------LGLDEAElpfVGELIEVRPEEErwrgaIERVLGGFALTllVPPEHYAAALRwvnrlhlr 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  503 ------KLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGL--------E 568
Cdd:COG4913    512 grlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVCVDSPEELRRHPRAITRAGQvkgngtrhE 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  569 GSLRVAEQAQEVL----EQQLPTLRHERSRLQEQLAQLSRQLSGREQELE--QARRAAQRQMEALERAAREKEALAKERA 642
Cdd:COG4913    592 KDDRRRIRSRYVLgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIA 671

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  643 GLAVQLAAAER---EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLtGELAGLRQQII 719
Cdd:COG4913    672 ELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA-EDLARLELRAL 750

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834693  720 AIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 775
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETAD 806
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1341-1754 9.47e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 9.47e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1341 QAEMALQEESVRRSERERRATL--DQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLE 1418
Cdd:COG1196    208 QAEKAERYRELKEELKELEAELllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1419 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEAL 1498
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1499 AQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQL 1578
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1579 REVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEA-EKREVERSALRLEKDRVALRRTLDKVEREKLRSHE 1657
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAArLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1658 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLE 1737
Cdd:COG1196    528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                          410
                   ....*....|....*..
gi 1622834693 1738 ARERAHRQRVRGLEEQV 1754
Cdd:COG1196    608 LREADARYYVLGDTLLG 624
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 327-660 2.26e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.33  E-value: 2.26e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  327 RALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 406
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  407 EEEQEDavqdgarVRRELERSHRQLEQLEgkrsvlaKELVEVREALsrATLQRDMLQAEKAEVAEALTKAEAGRVELELS 486
Cdd:TIGR02169  750 EQEIEN-------VKSELKELEARIEELE-------EDLHKLEEAL--NDLEARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  487 MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG 566
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  567 LEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQE----------------LEQARRAAQRQMEALE-- 628
Cdd:TIGR02169  894 LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPkgedeeipeeelsledVQAELQRVEEEIRALEpv 973

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1622834693  629 --RAAREKEALAKERAGLAVQLAAAEREGRTLSE 660
Cdd:TIGR02169  974 nmLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 14-785 2.43e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 2.43e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693   14 QALSEDIRKVtsDWARSRKELEQREAAWRREEESFNAY---FSNEHSRLLLLWRQVVGFRRLVSEVkmftERDLLQLGGE 90
Cdd:TIGR02168  216 KELKAELREL--ELALLVLRLEELREELEELQEELKEAeeeLEELTAELQELEEKLEELRLEVSEL----EEEIEELQKE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693   91 LARTSRAVQEaglgLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQsdldKADLSARVTELGLAVE 170
Cdd:TIGR02168  290 LYALANEISR----LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK----LEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  171 RLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEglQQTLRDlaqavlsdsesgvQLSGSERTADASDGSLRGL 250
Cdd:TIGR02168  362 ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE--IERLEA-------------RLERLEDRRERLQQEIEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  251 SGQRtpspprrsspgrgrsprrgpspacsDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALE 330
Cdd:TIGR02168  427 LKKL-------------------------EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  331 EQLQRLRDKTDGA---MQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQqaeelrQEREKLQAAQEELRRQRDRLE 407
Cdd:TIGR02168  482 RELAQLQARLDSLerlQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEG------YEAAIEAALGGRLQAVVVENL 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  408 EEQEDAVQDGARVR--------------RELERSHRQLEQLEGKRSVLAKELVEVREALSRA------------------ 455
Cdd:TIGR02168  556 NAAKKAIAFLKQNElgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvddldnal 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  456 -------------TLQRDMLQAEKAeVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 522
Cdd:TIGR02168  636 elakklrpgyrivTLDGDLVRPGGV-ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  523 AQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQL 602
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  603 SRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQ 682
Cdd:TIGR02168  795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  683 LAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMA------QKLVQAEREAQASLREQRAAHEE 756
Cdd:TIGR02168  875 LEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAqlelrlEGLEVRIDNLQERLSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*....
gi 1622834693  757 DLQRLQREKEAAWRELEAERAQLQSQLQR 785
Cdd:TIGR02168  955 EAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 313-1137 2.51e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 2.51e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  313 GTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ-------VAQQQAEEL 385
Cdd:pfam02463  142 GKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQakkaleyYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  386 RQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAE 465
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  466 KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATV 545
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  546 AREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQME 625
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  626 ALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKE 705
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  706 TLTGELAGLRQQIIAIQEKASLDKE--------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERA 777
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQKLvraltelpLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  778 QLQSQLQREQEELLARLEAEKEELSEEIATLQQERdeglLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 857
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEE----GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  858 QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLR 937
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  938 RELLEAQRKLRESQEGREVQRQEagELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEAR 1017
Cdd:pfam02463  778 EEREKTEKLKVEEEKEEKLKAQE--EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1018 TAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETlgLRQRLLKG 1097
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE--EAEILLKY 933

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622834693 1098 EASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1137
Cdd:pfam02463  934 EEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELG 973
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
572-1130 3.69e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 68.40  E-value: 3.69e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  572 RVAEQAQEVLEQ--QLPTLRHERSRLQEQLAQLS--RQLSGREQELEQARRAAQRQMEALE--RAAREKEALAKERAGLA 645
Cdd:COG4913    222 DTFEAADALVEHfdDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRlwFAQRRLELLEAELEELR 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  646 VQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQ-RQLAQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEK 724
Cdd:COG4913    302 AELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERE-------LEERERRRARLEALLAALGLP 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  725 ASLDKE------LMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQlQSQLQREQEELLARLEAEK 798
Cdd:COG4913    375 LPASAEefaalrAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR-KSNIPARLLALRDALAEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  799 EELSEE-------IATLQQERD-----EGLLlaeseKQQALSLKESEKT--ALSEKLMGTRHSLATISLEMERQKRDAQS 864
Cdd:COG4913    454 GLDEAElpfvgelIEVRPEEERwrgaiERVL-----GGFALTLLVPPEHyaAALRWVNRLHLRGRLVYERVRTGLPDPER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  865 RQEQDRSTVNALTSELRDLRAQLEEAVAAHAQevRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELL--- 941
Cdd:COG4913    529 PRLDPDSLAGKLDFKPHPFRAWLEAELGRRFD--YVCVDSPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRYVlgf 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  942 EAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANE--DKEQKLALLEEARTA 1019
Cdd:COG4913    607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDASSDD 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1020 VGkeagELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEA 1099
Cdd:COG4913    687 LA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1622834693 1100 SLEVMRQELQVAQRKLQEQEGEFRTRERRLL 1130
Cdd:COG4913    763 VERELRENLEERIDALRARLNRAEEELERAM 793
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 747-1482 4.45e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 4.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  747 LREQRAaHEEDLQRLQREKE--------AAWRELEAERAQLQSQLQREQEELlARLEAEKEELSEEIATLQQERDEglll 818
Cdd:TIGR02169  203 LRRERE-KAERYQALLKEKReyegyellKEKEALERQKEAIERQLASLEEEL-EKLTEEISELEKRLEEIEQLLEE---- 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  819 aESEKQQALSLKES-EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEavaaHAQE 897
Cdd:TIGR02169  277 -LNKKIKDLGEEEQlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE----ERKR 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  898 VRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGE------G 971
Cdd:TIGR02169  352 RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADlnaaiaG 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  972 AKER-EALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRR 1050
Cdd:TIGR02169  432 IEAKiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRA 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1051 QMKMLDSEN-------TRLGRELAELQGRL--ALGER------AEKESRRETLGLRQRLLKGEAS------LEVMRQELQ 1109
Cdd:TIGR02169  512 VEEVLKASIqgvhgtvAQLGSVGERYATAIevAAGNRlnnvvvEDDAVAKEAIELLKRRKAGRATflplnkMRDERRDLS 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1110 VAQRK--------LQEQEGEFRTRERRLLGS--LEEARGTEKQQLDHARGLELKLEATRAEAAELG--LRLSAAEGRAQG 1177
Cdd:TIGR02169  592 ILSEDgvigfavdLVEFDPKYEPAFKYVFGDtlVVEDIEAARRLMGKYRMVTLEGELFEKSGAMTGgsRAPRGGILFSRS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1178 LEAELARVEAQRRAAEAQLGGLRSALRRGLGLgrapspaprpvpgspaRDAAAGGSGDGLSSPSNLECSPGSQPPspgpa 1257
Cdd:TIGR02169  672 EPAELQRLRERLEGLKRELSSLQSELRRIENR----------------LDELSQELSDASRKIGEIEKEIEQLEQ----- 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1258 tspappdlDPETVRGALQEFLQELRSAQRER--------------DDLRTQTSALSHQLAEMEAERDHATLR-----ARQ 1318
Cdd:TIGR02169  731 --------EEEKLKERLEELEEDLSSLEQEIenvkselkeleariEELEEDLHKLEEALNDLEARLSHSRIPeiqaeLSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1319 LQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEG 1398
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1399 DKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVAD------SEVKAGTLQLTVER 1472
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeEELSLEDVQAELQR 962

                          810
                   ....*....|
gi 1622834693 1473 LNGALAKVEE 1482
Cdd:TIGR02169  963 VEEEIRALEP 972
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1365-1700 5.40e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 5.40e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1365 IATLERSLQATESELRASQEKISKmkaNETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQA 1444
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIER---LDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1445 LQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKV--------EESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQ 1516
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1517 KALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMV 1596
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1597 QKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGA 1676
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340
                   ....*....|....*....|....
gi 1622834693 1677 ELELAEAQRQIQQLEAQVVVLEQS 1700
Cdd:TIGR02169  482 EKELSKLQRELAEAEAQARASEER 505
mukB PRK04863
chromosome partition protein MukB;
286-1071 1.62e-10

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 66.52  E-value: 1.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  286 LIHSALHKRQlQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLS 365
Cdd:PRK04863   284 HLEEALELRR-ELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  366 ReksnLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQE-------------DAVQDGARVRRELERSHRQLE 432
Cdd:PRK04863   363 R----LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQaldvqqtraiqyqQAVQALERAKQLCGLPDLTAD 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  433 QLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQdsLSKLSALNESLA 512
Cdd:PRK04863   439 NAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARELLRR--LREQRHLAEQLQ 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  513 QDKLDLNRLVAQLEEEKAAlQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHER 592
Cdd:PRK04863   517 QLRMRLSELEQRLRQQQRA-ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARI 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  593 SRL----------QEQLAQLSRQlSGREQEleqarrAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLS--- 659
Cdd:PRK04863   596 QRLaarapawlaaQDALARLREQ-SGEEFE------DSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSqpg 668

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  660 -EEATRLRLEKEALEGSL---------------FE-----------------VQRQLAQLEARREHL------------- 693
Cdd:PRK04863   669 gSEDPRLNALAERFGGVLlseiyddvsledapyFSalygparhaivvpdlsdAAEQLAGLEDCPEDLyliegdpdsfdds 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  694 --EAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELmaqKLVQAEREAQASLREQRAAHEEDLQRL---------- 761
Cdd:PRK04863   749 vfSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRI---EQLRAEREELAERYATLSFDVQKLQRLhqafsrfigs 825

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  762 ------QREKEAAWRELEAERAQLQSQLQREQEELLaRLEAEKEELSEEIATLQQERDE-GLLLAESEKQQALSLKESEK 834
Cdd:PRK04863   826 hlavafEADPEAELRQLNRRRVELERALADHESQEQ-QQRSQLEQAKEGLSALNRLLPRlNLLADETLADRVEEIREQLD 904

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  835 TALSEKLMGTRHSLATISLE---------------MERQKRDAQSRQEQDRSTVNALTsELRDLRAQLeeavaAHAQEVR 899
Cdd:PRK04863   905 EAEEAKRFVQQHGNALAQLEpivsvlqsdpeqfeqLKQDYQQAQQTQRDAKQQAFALT-EVVQRRAHF-----SYEDAAE 978

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  900 RLQEQAQdlgkqrdsclrEAEELRTQLRLLEDARDGLRRELLEAQRKLRES-------QEGREVQRQEAGELRRSLG--- 969
Cdd:PRK04863   979 MLAKNSD-----------LNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYnqvlaslKSSYDAKRQMLQELKQELQdlg 1047

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  970 ----EGAKEREALRRsnEELRAAVKKAESERISLklanedkEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARREL 1045
Cdd:PRK04863  1048 vpadSGAEERARARR--DELHARLSANRSRRNQL-------EKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGW 1118

                          890       900
                   ....*....|....*....|....*.
gi 1622834693 1046 QELRRQMKMLDSENTRLGRELAELQG 1071
Cdd:PRK04863  1119 CAVLRLVKDNGVERRLHRRELAYLSA 1144
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1004-1621 4.10e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 65.32  E-value: 4.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1004 EDKEQKLALLEEARTAvGKEAGELRTGLQEVERsrLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKES 1083
Cdd:COG4913    245 EDAREQIELLEPIREL-AERYAAARERLAELEY--LRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1084 RRETLGLRQRLLK-GEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQL--------DHARGLELKL 1154
Cdd:COG4913    322 REELDELEAQIRGnGGDRLEQLEREIERLERELEERERR-RARLEALLAALGLPLPASAEEFaalraeaaALLEALEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1155 EATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSP--------APRPVPGSPAR 1226
Cdd:COG4913    401 EALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAI 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1227 DAAAGGSGDGLSSPSNLECSPGSQppspgpatspappdLDPETVRGALQefLQELRSAQRERDDLRTQTSALSHQL---- 1302
Cdd:COG4913    481 ERVLGGFALTLLVPPEHYAAALRW--------------VNRLHLRGRLV--YERVRTGLPDPERPRLDPDSLAGKLdfkp 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1303 --------AEMEAERDHATLRarqlqkAVAESEEARRSV--DG--RLSGVQAEMALQEESVRRSERERRATlDQIATLER 1370
Cdd:COG4913    545 hpfrawleAELGRRFDYVCVD------SPEELRRHPRAItrAGqvKGNGTRHEKDDRRRIRSRYVLGFDNR-AKLAALEA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1371 SLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR-----EAQAQAL 1445
Cdd:COG4913    618 ELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDdlaalEEQLEEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1446 QDRVDSLQRQVADSEVKAGTLQltvERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHD 1525
Cdd:COG4913    698 EAELEELEEELDELKGEIGRLE---KELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1526 RQVLQERLDAARQALSEARKQ-SSSLGEQVQTLRGEVADLE-----LQQVEAEG---QLQQLREVLRQRQEGEAAALHmv 1596
Cdd:COG4913    775 IDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPeylalLDRLEEDGlpeYEERFKELLNENSIEFVADLL-- 852

                          650       660
                   ....*....|....*....|....*
gi 1622834693 1597 QKLQDERRLLQERLGSLQRALAQLE 1621
Cdd:COG4913    853 SKLRRAIREIKERIDPLNDSLKRIP 877
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
742-1194 7.62e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.29  E-value: 7.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  742 EAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEelLARLEAEKEELSEEIATLQQERDEgLLLAES 821
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE--LETLEAEIEDLRETIAETEREREE-LAEEVR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  822 EKQQALSLKESEKTALSEKLMGTRHSLATISL---EMERQKRDAQSRQEQDRSTVNALTSELRDLRaqleEAVAAHAQEV 898
Cdd:PRK02224   283 DLRERLEELEEERDDLLAEAGLDDADAEAVEArreELEDRDEELRDRLEECRVAAQAHNEEAESLR----EDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  899 RRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 978
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  979 R---RSNEELRAA-------------------------VKKAESERISLKLANEDKEQKLALLEEARTAvGKEAGELRTG 1030
Cdd:PRK02224   439 RervEEAEALLEAgkcpecgqpvegsphvetieedrerVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1031 LQEVE------RSRLEARRE-LQELRRQMKMLDSEN-------TRLGRELAELQGRLAL--GERAEKESRRETLGLRQRL 1094
Cdd:PRK02224   518 REDLEeliaerRETIEEKRErAEELRERAAELEAEAeekreaaAEAEEEAEEAREEVAElnSKLAELKERIESLERIRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1095 LKGEASLEVMRQELQVAQRKLQEQE-------GEFRTRERRLLGSLEEARGTEKQQlDHARG------LELKLEATRAEA 1161
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNderrerlAEKRERKRELEAEFDEARIEEARE-DKERAeeyleqVEEKLDELREER 676

                          490       500       510
                   ....*....|....*....|....*....|....*.
gi 1622834693 1162 AELGLRLSAAEGRAQGLEA---ELARVEAQRRAAEA 1194
Cdd:PRK02224   677 DDLQAEIGAVENELEELEElreRREALENRVEALEA 712
PTZ00121 PTZ00121
MAEBL; Provisional
 315-872 8.12e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.39  E-value: 8.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  315 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 394
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  395 AQEELRRQRDRLEEEQEDAVQDGARVRRElerSHRQLEQLEGKrsvlAKELVEVREALSRATlqrdmlQAEKAEvaEALT 474
Cdd:PTZ00121  1400 AEEDKKKADELKKAAAAKKKADEAKKKAE---EKKKADEAKKK----AEEAKKADEAKKKAE------EAKKAE--EAKK 1464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  475 KAEAGRVELELsmtKLRAEEASLQDSLSKLSalneslAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATvareeqerle 554
Cdd:PTZ00121  1465 KAEEAKKADEA---KKKAEEAKKADEAKKKA------EEAKKKADEAKKAAEAKKKADEAKKAEEAKKAD---------- 1525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  555 elrleqevarqglegSLRVAEQAQEVLEQQlptlRHERSRLQEQLAQLSRQLSGRE-QELEQARRAAQRQMEALERAARE 633
Cdd:PTZ00121  1526 ---------------EAKKAEEAKKADEAK----KAEEKKKADELKKAEELKKAEEkKKAEEAKKAEEDKNMALRKAEEA 1586

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  634 KEAlakERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEgslfevqrqlaqlEARREHLEAEGQALLLAKETLTGELAg 713
Cdd:PTZ00121  1587 KKA---EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE-------------ELKKAEEEKKKVEQLKKKEAEEKKKA- 1649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  714 lrQQIIAIQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAA--WRELEAERAQLQSQLQREQEE 789
Cdd:PTZ00121  1650 --EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKaeEDEKKAAEALKKEAEEAKKAeeLKKKEAEEKKKAEELKKAEEE 1727

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  790 LLARLEAEKEELSEeiatlQQERDEGLLLAESEKQQALSLKESEktalsEKLMGTRHSLATISLEMERQKRDAQSRQEQD 869
Cdd:PTZ00121  1728 NKIKAEEAKKEAEE-----DKKKAEEAKKDEEEKKKIAHLKKEE-----EKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797


                   ...
gi 1622834693  870 RST 872
Cdd:PTZ00121  1798 KKI 1800
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1284-1750 1.12e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.78  E-value: 1.12e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1284 AQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDG-RLSGVQAEMALQEESVRRSERERRATL 1362
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGdRLEQLEREIERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1363 DQIATLERSLQATESELRASQEKIskmKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSD----- 1437
Cdd:COG4913    366 ALLAALGLPLPASAEEFAALRAEA---AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNiparl 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1438 ---REAQAQALQDRVDSLQ-----RQVADSEVK------------AGTLQLTVERLNGALAKVEESEGALR---DKVRGL 1494
Cdd:COG4913    443 lalRDALAEALGLDEAELPfvgelIEVRPEEERwrgaiervlggfALTLLVPPEHYAAALRWVNRLHLRGRlvyERVRTG 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1495 TEALAQSSASLNSTQDKnlhlqkaLTACEHD-----RQVLQERLDAA-----------RQALSEA--RKQSSSLGE---- 1552
Cdd:COG4913    523 LPDPERPRLDPDSLAGK-------LDFKPHPfrawlEAELGRRFDYVcvdspeelrrhPRAITRAgqVKGNGTRHEkddr 595

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1553 ---------------QVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEgEAAALHMVQKLQDErrllQERLGSLQRAL 1617
Cdd:COG4913    596 rrirsryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREALQRLAEYSWD----EIDVASAEREI 670

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1618 AQLEAEKREVERSALRLEkdrvALRRTLDKVEREKlrshedtVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVL 1697
Cdd:COG4913    671 AELEAELERLDASSDDLA----ALEEQLEELEAEL-------EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622834693 1698 EQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGL 1750
Cdd:COG4913    740 EDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
297-794 1.44e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.14  E-value: 1.44e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  297 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQ 376
Cdd:PRK02224   238 EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  377 VAQQQAEELRQEREKLQAAQEELRRQRDRLEE-------EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 449
Cdd:PRK02224   318 ELEDRDEELRDRLEECRVAAQAHNEEAESLREdaddleeRAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELR 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  450 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELElsmTKLRAEEASLQDSLSKLSA---------LNESLAQDKLDLNR 520
Cdd:PRK02224   398 ERFGDAPVDLGNAEDFLEELREERDELREREAELE---ATLRTARERVEEAEALLEAgkcpecgqpVEGSPHVETIEEDR 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  521 -LVAQLEEEKAALQGRQRQAEQEATVAREEQErleelrleqevARQGLEGSLRVAEQAQEVLEQQLPTLRHERsrlqEQL 599
Cdd:PRK02224   475 eRVEELEAELEDLEEEVEEVEERLERAEDLVE-----------AEDRIERLEERREDLEELIAERRETIEEKR----ERA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  600 AQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLS------EEATRLRLEKEALE 673
Cdd:PRK02224   540 EELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAaiadaeDEIERLREKREALA 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  674 GSLFEVQRQLAQLEARREHLEAE--GQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQ-KLVQAEREAQASLREQ 750
Cdd:PRK02224   620 ELNDERRERLAEKRERKRELEAEfdEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEiGAVENELEELEELRER 699

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1622834693  751 RAAHEEDLQRLQREKEAAwRELEAERAQLQSQLQREQEELLARL 794
Cdd:PRK02224   700 REALENRVEALEALYDEA-EELESMYGDLRAELRQRNVETLERM 742
PTZ00121 PTZ00121
MAEBL; Provisional
 723-1472 1.55e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 1.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  723 EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLqrekEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELS 802
Cdd:PTZ00121  1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKA----EEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  803 EEIATLQQERDEGLLLAESEK--QQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSEL 880
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  881 RDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRREllEAQRKLRESQEGREVQRQE 960
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD--EAKKKAEEAKKKADAAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  961 AGELRRSlGEGAKEREalRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTA--VGKEAGELRTGLQEVERSR 1038
Cdd:PTZ00121  1338 AEEAKKA-AEAAKAEA--EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdeAKKKAEEDKKKADELKKAA 1414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1039 LEARR--ELQELRRQMKMLDSENTRL--GRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK 1114
Cdd:PTZ00121  1415 AAKKKadEAKKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEE 1494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1115 LQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELglRLSAAEGRAQgleAELARVEAQRRAAEA 1194
Cdd:PTZ00121  1495 AKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE--KKKADELKKA---EELKKAEEKKKAEEA 1569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1195 QlgglRSALRRGLGLGRApspaprpvpgspardaaaggsgdglsspsnlecspGSQPPSPGPATSPAPPDLDPETVRGAl 1274
Cdd:PTZ00121  1570 K----KAEEDKNMALRKA-----------------------------------EEAKKAEEARIEEVMKLYEEEKKMKA- 1609

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1275 qeflQELRSAQRERDDlrtqtsalSHQLAEMEAERDHATLRARQLQKAVAESEEARRSvdgrlsgvQAEMALQEESVRRS 1354
Cdd:PTZ00121  1610 ----EEAKKAEEAKIK--------AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA--------EEENKIKAAEEAKK 1669

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1355 ERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1434
Cdd:PTZ00121  1670 AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA 1749

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1622834693 1435 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVER 1472
Cdd:PTZ00121  1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 329-1001 1.63e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.21  E-value: 1.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  329 LEEQLQRLRDKTDGAMQAQ-EDAQREVQRLRSANELlsrEKSNLAHSLQVAQQQAEELRQErekLQAAQEELRRQRDRLE 407
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLlQQHQDRIEQLISEHEV---EITGLTEKASSARSQANSIQSQ---LEIIQEQARNQNSMYM 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  408 EEQEDAVQDGARVRRELERSHRQLEQlegKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK--AEAGRVELEL 485
Cdd:pfam15921  317 RQLSDLESTVSQLRSELREAKRMYED---KIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKllADLHKREKEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  486 SMTKLRAEEASLQDSLSKLSA--LNESLAQDKLDLNRLVAQLEEEKAALQGRQRQaeqeatvareeqerleelrleQEVA 563
Cdd:pfam15921  394 SLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAMKSECQGQMER---------------------QMAA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  564 RQGLEGSLrvaeqaqevleQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAG 643
Cdd:pfam15921  453 IQGKNESL-----------EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITK 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  644 LAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQalLLAKEtltGELAGLRQQiiaiqE 723
Cdd:pfam15921  522 LRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ--LVGQH---GRTAGAMQV-----E 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  724 KASLDKELMAQKLvqaereaqaslreqraaHEEDLQRLQREKEAAWRELEAERAQLQSQLQReqeellarleaekeelse 803
Cdd:pfam15921  592 KAQLEKEINDRRL-----------------ELQEFKILKDKKDAKIRELEARVSDLELEKVK------------------ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  804 eiatlqqerdegLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL 883
Cdd:pfam15921  637 ------------LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSA 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  884 RAQLE---------EAVAAHAQEVrrlqeqAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRE---LLEAQRKLreSQ 951
Cdd:pfam15921  705 QSELEqtrntlksmEGSDGHAMKV------AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEkhfLKEEKNKL--SQ 776

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834693  952 EGREVQRQE---AGEL------RRSLGEGAKERE-ALRRSN---EELRAAVKKAESERISLKL 1001
Cdd:pfam15921  777 ELSTVATEKnkmAGELevlrsqERRLKEKVANMEvALDKASlqfAECQDIIQRQEQESVRLKL 839
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 291-1140 2.48e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 62.76  E-value: 2.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  291 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQE---------------DAQREVQ 355
Cdd:TIGR00606  250 LKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYhnhqrtvrekerelvDCQRELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  356 RLRSANELLSREKSNLahslqVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQeDAVQDGARVRRELERSHR-QLEQL 434
Cdd:TIGR00606  330 KLNKERRLLNQEKTEL-----LVEQGRLQLQADRHQEHIRARDSLIQSLATRLEL-DGFERGPFSERQIKNFHTlVIERQ 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  435 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEAL----TKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNES 510
Cdd:TIGR00606  404 EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIelkkEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  511 LAQ-DKLDLNRLVAQLEEEKAALQGRQ----RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQA-------- 577
Cdd:TIGR00606  484 ERElSKAEKNSLTETLKKEVKSLQNEKadldRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKsrhsdelt 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  578 --------QEVLEQQLPTLRHERSRLQEQLAQLSRQLsgreQELEQARRAAQRQMEALEraarEKEALAKERAGLAVQLA 649
Cdd:TIGR00606  564 sllgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKEL----ASLEQNKNHINNELESKE----EQLSSYEDKLFDVCGSQ 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  650 AAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQI-IAIQEKASLD 728
Cdd:TIGR00606  636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLrLAPDKLKSTE 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  729 KELmaqKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQrEQEELLARLEAEKEELSEEIATL 808
Cdd:TIGR00606  716 SEL---KKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE-EQETLLGTIMPEEESAKVCLTDV 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  809 QQERDEGLLLAESEKQQALSLKESEK-------TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRStVNALTSELR 881
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKLQGsdldrtvQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH-LKSKTNELK 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  882 DLRAQLEEAvaahAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA 961
Cdd:TIGR00606  871 SEKLQIGTN----LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDI 946

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  962 GELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKlalleeartavgKEAGELRTGLQEVERSRLEA 1041
Cdd:TIGR00606  947 KEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQE------------KINEDMRLMRQDIDTQKIQE 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1042 RRELQELRRQMKmlDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ---ELQVAQRKLQEQ 1118
Cdd:TIGR00606 1015 RWLQDNLTLRKR--ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQkgyEKEIKHFKKELR 1092

                          890       900
                   ....*....|....*....|..
gi 1622834693 1119 EGEFRTRERRLLGSLEEARGTE 1140
Cdd:TIGR00606 1093 EPQFRDAEEKYREMMIVMRTTE 1114
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
573-1095 6.50e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 61.21  E-value: 6.50e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  573 VAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQlsgREQElEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAE 652
Cdd:PRK02224   196 IEEKEEKDLHERLNGLESELAELDEEIERYEEQ---REQA-RETRDEADEVLEEHEERREELETLEAEIEDLRETIAETE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  653 REGRTLSEEATRLRLEKEALEgslfevqRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASldkelM 732
Cdd:PRK02224   272 REREELAEEVRDLRERLEELE-------EERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ-----A 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  733 AQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLqSQLQREQEELLARLEAEKEELSEEIATLQQER 812
Cdd:PRK02224   340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI-EELEEEIEELRERFGDAPVDLGNAEDFLEELR 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  813 DEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRdaQSRQEQDRSTVNALTSELRDLRAQLE---- 888
Cdd:PRK02224   419 EERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPH--VETIEEDRERVEELEAELEDLEEEVEevee 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  889 -----EAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGE 963
Cdd:PRK02224   497 rleraEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  964 LRRSLGEGAKEREALRRSnEELRAAVKKAESERISLklaNEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLE-AR 1042
Cdd:PRK02224   577 LNSKLAELKERIESLERI-RTLLAAIADAEDEIERL---REKREALAELNDERRERLAEKRERKRELEAEFDEARIEeAR 652

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693 1043 RELQELRRQMKMLDSENTRLGRELAELQGRL-----ALGERAEKESRRETLGLRQRLL 1095
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIgavenELEELEELRERREALENRVEAL 710
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 315-1128 6.78e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 61.14  E-value: 6.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  315 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKL-- 392
Cdd:pfam02463  197 LQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENke 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  393 -QAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAE 471
Cdd:pfam02463  277 eEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  472 ALTKAEAGRVELELSMTKLRAEEASLQDSLSK-LSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQ 550
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSaAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  551 ERLEELRLEQEVARQGLEgSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRqmealera 630
Cdd:pfam02463  437 ESIELKQGKLTEEKEELE-KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARS-------- 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  631 aREKEALAKERAGLAVQLAAAEREGRTLSEEATrlrLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGE 710
Cdd:pfam02463  508 -GLKVLLALIKDGVGGRIISAHGRLGDLGVAVE---NYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLL 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  711 LAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwRELEAERAQLQSQLQREQEEL 790
Cdd:pfam02463  584 IPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA-KAKESGLRKGVSLEEGLAEKS 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  791 LARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSE----KLMGTRHSLATISLEMERQKRDAQSRQ 866
Cdd:pfam02463  663 EVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEElkklKLEAEELLADRVQEAQDKINEELKLLK 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  867 EQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQ 944
Cdd:pfam02463  743 QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTekLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  945 RKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEA 1024
Cdd:pfam02463  823 LIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1025 GELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLAlgERAEKESRRETLGLRQRLLKGEASLEVM 1104
Cdd:pfam02463  903 EEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEE--NNKEEEEERNKRLLLAKEELGKVNLMAI 980

                          810       820
                   ....*....|....*....|....
gi 1622834693 1105 RQELQVAQRKLQEQEGEFRTRERR 1128
Cdd:pfam02463  981 EEFEEKEERYNKDELEKERLEEEK 1004
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 322-794 9.87e-09

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 60.58  E-value: 9.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  322 SESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANElLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ--EEL 399
Cdd:PRK10246   214 TPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRLDE-LQQEASRRQQALQQALAAEEKAQPQLAALSLAQpaRQL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  400 RRQRDRLeEEQEDAVqdgARVRRELERSHRQLEQLEGKRSvlakelvEVREALSRatlQRDMLQAEKAEVAEALTKAEAG 479
Cdd:PRK10246   293 RPHWERI-QEQSAAL---AHTRQQIEEVNTRLQSTMALRA-------RIRHHAAK---QSAELQAQQQSLNTWLAEHDRF 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  480 RVeLELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-------RLVAQLEEEKAALQGRQRQAEQEATVAREEQER 552
Cdd:PRK10246   359 RQ-WNNELAGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNalpaitlTLTADEVAAALAQHAEQRPLRQRLVALHGQIVP 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  553 LEELRLEQEVARQGlegslrvAEQAQEVLEQQLPTLRHERSRLQEQLAQLSR--QLSGREQELEQARRAAQRQMEALERA 630
Cdd:PRK10246   438 QQKRLAQLQVAIQN-------VTQEQTQRNAALNEMRQRYKEKTQQLADVKTicEQEARIKDLEAQRAQLQAGQPCPLCG 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  631 AREKEALAkerAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGE 710
Cdd:PRK10246   511 STSHPAVE---AYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCAS 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  711 LAGLR-----------------QQIIAIQEKASLDKELMAQKlvQAEREAQASLREQRAAHEEDLQRL-----QREKEAA 768
Cdd:PRK10246   588 LNITLqpqddiqpwldaqeeheRQLRLLSQRHELQGQIAAHN--QQIIQYQQQIEQRQQQLLTALAGYaltlpQEDEEAS 665

                          490       500
                   ....*....|....*....|....*.
gi 1622834693  769 WRELEAERAQLQSQLQREQEELLARL 794
Cdd:PRK10246   666 WLATRQQEAQSWQQRQNELTALQNRI 691
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
575-1127 1.07e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.46  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  575 EQAQEVLEQQLPTLRHERSRLQEQLAQ---LSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERaglavqlaaa 651
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRtenIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV---------- 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  652 eREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQalllaketltgELAGLRQQIIAIQEKASLDKEL 731
Cdd:PRK03918   231 -KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE-----------ELEEKVKELKELKEKAEEYIKL 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  732 MA--QKLVQAEREAQ---ASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQREQE-----ELLARLEAEKEEL 801
Cdd:PRK03918   299 SEfyEEYLDELREIEkrlSRLEEEINGIEERIKELE-EKEERLEELKKKLKELEKRLEELEErhelyEEAKAKKEELERL 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  802 SEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD-----AQSRQEQDRSTVNAL 876
Cdd:PRK03918   378 KKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgRELTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  877 TSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDscLREAEELRTQLRLLEDARDGLRRELLEaqRKLRESQEGREV 956
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE--LIKLKELAEQLKELEEKLKKYNLEELE--KKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  957 QRQEAGELrRSLGEGAKEREALRRSNEELRAAVKKAESERISLK--------LANEDKEQKLALLEEARtavgKEAGELR 1028
Cdd:PRK03918   534 LIKLKGEI-KSLKKELEKLEELKKKLAELEKKLDELEEELAELLkeleelgfESVEELEERLKELEPFY----NEYLELK 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1029 TGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR---ELAELQGRLAlgERAEKESRRETLGLRQRLLKGEASLEVMR 1105
Cdd:PRK03918   609 DAEKELEREEKELKKLEEELDKAFEELAETEKRLEElrkELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELE 686

                          570       580
                   ....*....|....*....|..
gi 1622834693 1106 QELQVAQRKLQEQEGEFRTRER 1127
Cdd:PRK03918   687 KRREEIKKTLEKLKEELEEREK 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 371-622 1.18e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 1.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  371 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVRE 450
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  451 ALSRATLQRDMLQAEKAEVAEALTKAEagrvelELSMTKLRAEEASLQDSLSKLSALNESLAQDKldlnRLVAQLEEEKA 530
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRLG------RQPPLALLLSPEDFLDAVRRLQYLKYLAPARR----EQAEELRADLA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  531 ALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGRE 610
Cdd:COG4942    161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240

                          250
                   ....*....|..
gi 1622834693  611 QELEQARRAAQR 622
Cdd:COG4942    241 ERTPAAGFAALK 252
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 322-535 1.53e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  322 SESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRR 401
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  402 QRDRLEEEQEDAVQDGARVRR-----------ELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVA 470
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRqpplalllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693  471 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGR 535
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
667-1205 1.57e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  667 LEKEALEGSLFEVQRQLAQL-EARREHLEAEGQALLLAketltgELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQA 745
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLeRAHEALEDAREQIELLE------PIRELAERYAAARERLAELEYLRAALRLWFAQRRLE 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  746 SLREQRAAHEEDLQRLQREK---EAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEgllLAESE 822
Cdd:COG4913    292 LLEAELEELRAELARLEAELerlEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR---LEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  823 KQQALSLKESEK--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQlEEAVAAHAQEVRR 900
Cdd:COG4913    369 AALGLPLPASAEefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR-KSNIPARLLALRD 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  901 lqEQAQDLGKQRDSC--------LREAEE---------LRTQ-LRLLEDARDglRRELLEA--QRKLRESQEGREVQRQE 960
Cdd:COG4913    448 --ALAEALGLDEAELpfvgelieVRPEEErwrgaiervLGGFaLTLLVPPEH--YAAALRWvnRLHLRGRLVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  961 AGELRRSLGEGA-------KEREALRRSNEEL--RAAVKKAESERislKLANEDKeqklALLEEARTAVGKEAGELRTGL 1031
Cdd:COG4913    524 PDPERPRLDPDSlagkldfKPHPFRAWLEAELgrRFDYVCVDSPE---ELRRHPR----AITRAGQVKGNGTRHEKDDRR 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1032 QEVE--------RSRLEA-RRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEK------------ESRRETLGL 1090
Cdd:COG4913    597 RIRSryvlgfdnRAKLAAlEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEyswdeidvasaeREIAELEAE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1091 RQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRlLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSA 1170
Cdd:COG4913    677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGE-IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1622834693 1171 AEGRAQGLEAELAR-VEAQRRAAEAQLGGLRSALRR 1205
Cdd:COG4913    756 AAALGDAVERELREnLEERIDALRARLNRAEEELER 791
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
831-1193 1.91e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 1.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  831 ESEKTALSEKLMGTRHSLATISLEMER---QKRDAQ----------SRQEQDRSTVNALTSELRDLRAQLEEAV---AAH 894
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERyeeQREQARetrdeadevlEEHEERREELETLEAEIEDLRETIAETErerEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  895 AQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLREsqegrevQRQEAGELRRSLGEGAKE 974
Cdd:PRK02224   278 AEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE-------CRVAAQAHNEEAESLRED 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  975 REALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKM 1054
Cdd:PRK02224   351 ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1055 LDSENTRLGRELAELQGRLA------LGERAEKESRRETLG-LRQRLLKGEASLEVMRQELQVAQRKLQEQEgEFRTRER 1127
Cdd:PRK02224   431 LEATLRTARERVEEAEALLEagkcpeCGQPVEGSPHVETIEeDRERVEELEAELEDLEEEVEEVEERLERAE-DLVEAED 509

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1128 RLLGSLEEARGTEKQQLDHARGLE---LKLEATRAEAAElgLRLSAAEGRAQGLEAELARVEAQRRAAE 1193
Cdd:PRK02224   510 RIERLEERREDLEELIAERRETIEekrERAEELRERAAE--LEAEAEEKREAAAEAEEEAEEAREEVAE 576
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-543 2.17e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693    2 LREQLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEESfnayfSNEHSRLLLLWRQvvgfRRLVSEVKMFTE 81
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE-----LEELEEELEELEE----ELEEAEEELEEA 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693   82 RDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSAR 161
Cdd:COG1196    357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  162 VTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTAD 241
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  242 ASDGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQ------LQVQDMRGRYEASQDLLGTL 315
Cdd:COG1196    517 AGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKagratfLPLDKIRARAALAAALARGA 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  316 RKQLSDS-ESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 394
Cdd:COG1196    597 IGAAVDLvASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  395 AQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEgkrsvlaKELVEVREALSRATLQRDMLQAEKAEVAEALT 474
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL-------EEELEEEALEEQLEAEREELLEELLEEEELLE 749

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834693  475 KAEAGRVELELSMTKLRAEEASLQDSLSKLSALN-------ESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEA 543
Cdd:COG1196    750 EEALEELPEPPDLEELERELERLEREIEALGPVNllaieeyEELEERYDFLSEQREDLEEARETLEEAIEEIDRET 825
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 291-1204 2.22e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  291 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRlrdKTDGAMQAQEDAQREVQRLRSANELLSREKSN 370
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQA---ETELCAEAEEMRARLAARKQELEEILHELESR 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  371 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELE----------RSHRQLEQLEGKRSV 440
Cdd:pfam01576   84 LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEdillledqnsKLSKERKLLEERISE 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  441 LAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSA----LNESLAQDKL 516
Cdd:pfam01576  164 FTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAqiaeLRAQLAKKEE 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  517 DLNRLVAQLEEE---KAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERS 593
Cdd:pfam01576  244 ELQAALARLEEEtaqKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRS 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  594 RLQEQLAQLSRQL-------SGREQELEQARRAAQRQM-EALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRL 665
Cdd:pfam01576  324 KREQEVTELKKALeeetrshEAQLQEMRQKHTQALEELtEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDS 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  666 RLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQ-EKASLDKELM-AQKLVQAEREA 743
Cdd:pfam01576  404 EHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSkDVSSLESQLQdTQELLQEETRQ 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  744 QASLREQRAAHEED---LQRLQREKEAAWRELEAERAQLQSQL------------------------QREQEELLARLEA 796
Cdd:pfam01576  484 KLNLSTRLRQLEDErnsLQEQLEEEEEAKRNVERQLSTLQAQLsdmkkkleedagtlealeegkkrlQRELEALTQQLEE 563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  797 EKEELSEEIAT---LQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTV 873
Cdd:pfam01576  564 KAAAYDKLEKTknrLQQELDD-LLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLA 642

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  874 NALtSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQ-------RDSCLREAEELRTQLRLLED----ARDGLRRelLE 942
Cdd:pfam01576  643 RAL-EEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNvhelersKRALEQQVEEMKTQLEELEDelqaTEDAKLR--LE 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  943 AQRKLRESQEGREVQ-RQEAG-ELRRSLGEGAKEREALRrsnEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAV 1020
Cdd:pfam01576  720 VNMQALKAQFERDLQaRDEQGeEKRRQLVKQVRELEAEL---EDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEA 796

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1021 GKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEAS 1100
Cdd:pfam01576  797 VKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASG 876

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1101 LEVMRQELQVAQRKLQEQEGEfrtrerrllgsLEEARGTEKQQLDHARGLELKLEATRAEaaelglrLSAAEGRAQGLEA 1180
Cdd:pfam01576  877 KSALQDEKRRLEARIAQLEEE-----------LEEEQSNTELLNDRLRKSTLQVEQLTTE-------LAAERSTSQKSES 938

                          970       980
                   ....*....|....*....|....
gi 1622834693 1181 ELARVEAQRRAAEAQLGGLRSALR 1204
Cdd:pfam01576  939 ARQQLERQNKELKAKLQEMEGTVK 962
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 310-1086 2.42e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.58  E-value: 2.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  310 DLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQrlrSANELLSReksnlahsLQVAQQQAEELRQER 389
Cdd:COG3096    285 ERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQ---AASDHLNL--------VQTALRQQEKIERYQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  390 EKLQAAQEELRRQRDRLEEEQEdavqdgarvrrELERSHRQLEQLEGKRSVLAKELVEVREAL----SRATLQRDMLQA- 464
Cdd:COG3096    354 EDLEELTERLEEQEEVVEEAAE-----------QLAEAEARLEAAEEEVDSLKSQLADYQQALdvqqTRAIQYQQAVQAl 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  465 EKAEVAEALTKAEAGRVELELSMTKLRAEEA-----SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQ--- 536
Cdd:COG3096    423 EKARALCGLPDLTPENAEDYLAAFRAKEQQAteevlELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTAREllr 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  537 ------RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQ--AQEVLEQQLPTLRHERSRLQEQLAQLSRQLSG 608
Cdd:COG3096    503 ryrsqqALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQldAAEELEELLAELEAQLEELEEQAAEAVEQRSE 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  609 REQELEQARrAAQRQMEALERAARE-KEALAKERAGLAVQLAAAEREGRTLSEEATRLRlekealegslfEVQRQLAQLE 687
Cdd:COG3096    583 LRQQLEQLR-ARIKELAARAPAWLAaQDALERLREQSGEALADSQEVTAAMQQLLERER-----------EATVERDELA 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  688 ARREHLEAEGQALLLA-----------KETLTGELAGLRQQIIAIQEKASLDKEL--MAQKLVQAEREAQASLREQRAAH 754
Cdd:COG3096    651 ARKQALESQIERLSQPggaedprllalAERLGGVLLSEIYDDVTLEDAPYFSALYgpARHAIVVPDLSAVKEQLAGLEDC 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  755 EEDLQRLQRE----KEAAWRELEAERAQLQSQLQRE-------QEELLARleaekEELSEEIATLQQERDEgllLAESEK 823
Cdd:COG3096    731 PEDLYLIEGDpdsfDDSVFDAEELEDAVVVKLSDRQwrysrfpEVPLFGR-----AAREKRLEELRAERDE---LAEQYA 802

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  824 QQALSLKESEKTALS-EKLMGTRHSLATIS------LEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQL--------- 887
Cdd:COG3096    803 KASFDVQKLQRLHQAfSQFVGGHLAVAFAPdpeaelAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLqllnkllpq 882

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  888 -----EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLE---DARDGLRRELLEAQRKLRESQEGRE---- 955
Cdd:COG3096    883 anllaDETLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFalse 962

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  956 -VQR------QEAGEL---RRSLGEGAKER-----EALRRSNEELRAAVKKAES---ERISLKLANEDKEQKLALLEEAR 1017
Cdd:COG3096    963 vVQRrphfsyEDAVGLlgeNSDLNEKLRARleqaeEARREAREQLRQAQAQYSQynqVLASLKSSRDAKQQTLQELEQEL 1042

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1018 TAVGKEAGELRTGLQEVERSRLEArrELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRE 1086
Cdd:COG3096   1043 EELGVQADAEAEERARIRRDELHE--ELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQ 1109
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
463-994 4.19e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.51  E-value: 4.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  463 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQE 542
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  543 ATVAREEQERLEELRLeqevARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEqlaqlsrqlsgreqELEQARRAAQR 622
Cdd:PRK02224   278 AEEVRDLRERLEELEE----ERDDLLAEAGLDDADAEAVEARREELEDRDEELRD--------------RLEECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  623 QMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLL 702
Cdd:PRK02224   340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELRE 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  703 AKETLTGELAGLRQQIIAIQEKASLDKELMA--------QKLVQAER-EAQASLREQRAAHEEDLQRLQREKEAawRELE 773
Cdd:PRK02224   420 ERDELREREAELEATLRTARERVEEAEALLEagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEE--VEER 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  774 AERAQLQSQLQREQEELLARLEaekeelseeiaTLQQERDEGLLLAESEKQQALSLKEsEKTALSEKLMGTRHSLATISL 853
Cdd:PRK02224   498 LERAEDLVEAEDRIERLEERRE-----------DLEELIAERRETIEEKRERAEELRE-RAAELEAEAEEKREAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  854 EMERqKRDAQSRQEQDRSTVNALTSELRDLRAQLEEaVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDAR 933
Cdd:PRK02224   566 EAEE-AREEVAELNSKLAELKERIESLERIRTLLAA-IADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834693  934 DGLRRELLEAQR------------KLRESQEGREVQRQEAGELRRSLgegaKEREALRRSNEELRAAVKKAES 994
Cdd:PRK02224   644 DEARIEEAREDKeraeeyleqveeKLDELREERDDLQAEIGAVENEL----EELEELRERREALENRVEALEA 712
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 588-1463 4.41e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.54  E-value: 4.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  588 LRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAvqlaaaEREGRTLSEEATRLRL 667
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG------EEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  668 EKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQ--A 745
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKefA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  746 SLREQRAAHEEDLQRLQREKEaawrELEAERAQLQSQLQREQEELlARLEAEKEELSEEIATLQQERDEGLLLAESEKQQ 825
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREIN----ELKRELDRLQEELQRLSEEL-ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  826 ALSLKEsEKTALSEKLMGTRHSLAtislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQlEEAVAAHAQEVRRLQEQA 905
Cdd:TIGR02169  457 LEQLAA-DLSKYEQELYDLKEEYD----RVEKELSKLQRELAEAEAQARASEERVRGGRAV-EEVLKASIQGVHGTVAQL 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  906 QDLGKQRDSCLREAEELRTQLRLLEDARDGLRR-ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNE 983
Cdd:TIGR02169  531 GSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAiELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVdLVEFDP 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  984 ELRAAVKKAeserISLKLANEDKEQKLALLEEAR--TAVGK--EAGELRTGLQEVERSR----LEARRELQELRRQMKML 1055
Cdd:TIGR02169  611 KYEPAFKYV----FGDTLVVEDIEAARRLMGKYRmvTLEGElfEKSGAMTGGSRAPRGGilfsRSEPAELQRLRERLEGL 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1056 DSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEqegefrtrerrllgsLEE 1135
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS---------------LEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1136 ARGTEKQQLDHARG----LELKLEATRAEAAELGLRLSaaEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRglglgr 1211
Cdd:TIGR02169  752 EIENVKSELKELEArieeLEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR------ 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1212 apspaprpvpgspardaaaggsgdglsspsnlecspgsqppspgpatspapPDLDPETVRGALQEFLQELRSAQRERDDL 1291
Cdd:TIGR02169  824 ---------------------------------------------------LTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1292 RTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERS 1371
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1372 LQATESELRASQEkISKMKANETKLEGDKRRLKEVLDASESRTVKL-----ELQRRSLEGELQRSRLglsdrEAQAQALQ 1446
Cdd:TIGR02169  933 LSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyeEVLKRLDELKEKRAKL-----EEERKAIL 1006

                          890
                   ....*....|....*..
gi 1622834693 1447 DRVDSLQRQVADSEVKA 1463
Cdd:TIGR02169 1007 ERIEEYEKKKREVFMEA 1023
PTZ00121 PTZ00121
MAEBL; Provisional
 970-1740 5.32e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 5.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  970 EGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARtavgkeagELRTGLQEVERSRLEARRELQELR 1049
Cdd:PTZ00121  1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAK--------KTETGKAEEARKAEEAKKKAEDAR 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1050 RQMKMLDSENTRLGREL--AELQGRLALGERAEKESRRETLGLRQRLLKGEAS---LEVMR-QELQVAQRKLQEQEGEFR 1123
Cdd:PTZ00121  1129 KAEEARKAEDARKAEEArkAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAArkaEEVRKaEELRKAEDARKAEAARKA 1208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1124 TRERRLlgslEEARGTEKQQLDHA--RGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGglrS 1201
Cdd:PTZ00121  1209 EEERKA----EEARKAEDAKKAEAvkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA---D 1281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1202 ALRRGLGLGRAPspaprpvpgspardaaaggsgdglsspsnlECSPGSQPPSPGPATSPAPPDLDPETVRGALQEFLQEL 1281
Cdd:PTZ00121  1282 ELKKAEEKKKAD------------------------------EAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1282 RSAQRERDDLRTQTSAlshQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGrlSGVQAEMALQEESVRRSERERRAT 1361
Cdd:PTZ00121  1332 DAAKKKAEEAKKAAEA---AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEAKKKAEEDKKK 1406

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1362 LDQIATLERSLQATESELRASQEKiskMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQ 1441
Cdd:PTZ00121  1407 ADELKKAAAAKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1442 aqalqdRVDSLQRQVADSEVKAGTLQLTVERLNGA--LAKVEESEGAlrDKVRGLTEALAQSSASLNSTQDKNLHLQKA- 1518
Cdd:PTZ00121  1484 ------KADEAKKKAEEAKKKADEAKKAAEAKKKAdeAKKAEEAKKA--DEAKKAEEAKKADEAKKAEEKKKADELKKAe 1555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1519 -LTACEHDRQVLQ-----ERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAA 1592
Cdd:PTZ00121  1556 eLKKAEEKKKAEEakkaeEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1593 LHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRT 1672
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK 1715

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693 1673 LTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARE 1740
Cdd:PTZ00121  1716 KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
760-1193 6.57e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 6.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  760 RLQREKEAAWRELEAERAQLQSqlqREQEELLARLEAEKEELSEEIATLQQERDEglllAESEKQQA---LSLKESEKTA 836
Cdd:PRK02224   180 RVLSDQRGSLDQLKAQIEEKEE---KDLHERLNGLESELAELDEEIERYEEQREQ----ARETRDEAdevLEEHEERREE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  837 LSEKLMGTRHSLATISlEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAahaqEVRRLQEQAQDLGKQRDSCL 916
Cdd:PRK02224   253 LETLEAEIEDLRETIA-ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDA----DAEAVEARREELEDRDEELR 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  917 REAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 996
Cdd:PRK02224   328 DRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  997 islklanEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA-- 1074
Cdd:PRK02224   408 -------GNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEel 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1075 LGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRerrllgsLEEARGTEKQQLDHARGLELKL 1154
Cdd:PRK02224   481 EAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRET-------IEEKRERAEELRERAAELEAEA 553

                          410       420       430
                   ....*....|....*....|....*....|....*....
gi 1622834693 1155 EATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAE 1193
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE 592
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
376-940 1.02e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  376 QVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEgkrsVLAKELVEVREALSRA 455
Cdd:PRK02224   195 QIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE----TLEAEIEDLRETIAET 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  456 tlqrdmlQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRlvaQLEEEKAALQGR 535
Cdd:PRK02224   271 -------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD---RLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  536 QRQAEQEATVAREeqerleelrleqevarqgLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLsrqlsgrEQELEQ 615
Cdd:PRK02224   341 NEEAESLREDADD------------------LEERAEELREEAAELESELEEAREAVEDRREEIEEL-------EEEIEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  616 ARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLS---EEATRLRLE------KEALEGS-----LFEVQR 681
Cdd:PRK02224   396 LRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARervEEAEALLEAgkcpecGQPVEGSphvetIEEDRE 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  682 QLAQLEARREHLEAEGQALLLAKETLTgELAGLRQQIIAIQEKASLDKELMAQK--LVQAEREAQASLREQRAAHEEDLQ 759
Cdd:PRK02224   476 RVEELEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERreTIEEKRERAEELRERAAELEAEAE 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  760 rlQREKEAAWRELEAERAQ-----LQSQLQREQEEL--LARLEAEKEELSEEIATLQ--QERDEGLLLAESEKQQALSLK 830
Cdd:PRK02224   555 --EKREAAAEAEEEAEEAReevaeLNSKLAELKERIesLERIRTLLAAIADAEDEIErlREKREALAELNDERRERLAEK 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  831 ESEKTALSEKLMGTRhslatisLEMERQKRDaqsRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGK 910
Cdd:PRK02224   633 RERKRELEAEFDEAR-------IEEAREDKE---RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREA 702

                          570       580       590
                   ....*....|....*....|....*....|
gi 1622834693  911 QRDSCLReAEELRTQLRLLEDARDGLRREL 940
Cdd:PRK02224   703 LENRVEA-LEALYDEAEELESMYGDLRAEL 731
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
660-1088 1.20e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  660 EEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQA 739
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  740 EREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEgLLLA 819
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE-LEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  820 ESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRD----AQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHA 895
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvLFLVLGLLALLFLLLAREKASLGKEAEELQALPA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  896 QEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRR-ELLEAQRKLRESQEGREVQRQEAG----ELRRSLGE 970
Cdd:COG4717    313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGvedeEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  971 GAKEREALRRSNEELRAAVKKAESERISLKLANEDK--EQKLALLEEARTAVGKEAGELRTGLQEVER--SRLEARRELQ 1046
Cdd:COG4717    393 QAEEYQELKEELEELEEQLEELLGELEELLEALDEEelEEELEELEEELEELEEELEELREELAELEAelEQLEEDGELA 472

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1622834693 1047 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETL 1088
Cdd:COG4717    473 ELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
289-668 1.59e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 1.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  289 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDK---TDGAMQAQEDAQREVQRLRSANELLS 365
Cdd:PRK02224   377 EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREReaeLEATLRTARERVEEAEALLEAGKCPE 456

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  366 REKSnLAHSLQVAqqQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVqdgarvrrELERSHRQLEQLEGKRSVLAKEL 445
Cdd:PRK02224   457 CGQP-VEGSPHVE--TIEEDRERVEELEAELEDLEEEVEEVEERLERAE--------DLVEAEDRIERLEERREDLEELI 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  446 VEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQdslSKLSALNESLAQdkldLNRLVAQL 525
Cdd:PRK02224   526 AERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELN---SKLAELKERIES----LERIRTLL 598

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  526 EEEKAALQGRQRQAEQEATVAREEQERLEELRleqevarqglEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQ 605
Cdd:PRK02224   599 AAIADAEDEIERLREKREALAELNDERRERLA----------EKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEK 668

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834693  606 LsgreQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAE---REGRTLSEEATRLRLE 668
Cdd:PRK02224   669 L----DELREERDDLQAEIGAVENELEELEELRERREALENRVEALEalyDEAEELESMYGDLRAE 730
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
881-1460 2.38e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 2.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  881 RDLRAQLEEAVAAHaQEVRRLQEQAQDLGKQRDSClREAEELRTQLRLLEDARDGLRreLLEAQRKLRESQEGREVQRQE 960
Cdd:COG4913    228 DALVEHFDDLERAH-EALEDAREQIELLEPIRELA-ERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAE 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  961 AGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI-SLKLANEDKEQKLALLEEARTAVGKEAGELR----TGLQEVE 1035
Cdd:COG4913    304 LARLEAELERLEARLDALREELDELEAQIRGNGGDRLeQLEREIERLERELEERERRRARLEALLAALGlplpASAEEFA 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1036 RSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA--LGERAEKESRRETLGLRQRLLKGE--ASLEVMRQELQVA 1111
Cdd:COG4913    384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRelEAEIASLERRKSNIPARLLALRDAlaEALGLDEAELPFV 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1112 QRKLQEQEGE-------------FRTR-------ERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAA 1171
Cdd:COG4913    464 GELIEVRPEEerwrgaiervlggFALTllvppehYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFK 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1172 EGRAQG-LEAELAR---------VEAQRRAAEA-QLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAaaggsgdglssp 1240
Cdd:COG4913    544 PHPFRAwLEAELGRrfdyvcvdsPEELRRHPRAiTRAGQVKGNGTRHEKDDRRRIRSRYVLGFDNRAK------------ 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1241 snlecspgsqppspgpatspappdldpetvrgaLQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERdhatlRARQLQ 1320
Cdd:COG4913    612 ---------------------------------LAALEAELAELEEELAEAEERLEALEAELDALQERR-----EALQRL 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1321 KAVAESEEARRSVDGRLSGVQAEMAlqeesvrrserERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDK 1400
Cdd:COG4913    654 AEYSWDEIDVASAEREIAELEAELE-----------RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKEL 722

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834693 1401 RRLKEVLDASESR---TVKLELQRRSLEGELQRSRLGLSDREAQ-AQALQDRVDSLQRQVADSE 1460
Cdd:COG4913    723 EQAEEELDELQDRleaAEDLARLELRALLEERFAAALGDAVERElRENLEERIDALRARLNRAE 786
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1271-1686 2.66e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.82  E-value: 2.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1271 RGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARrsvdgrlSGVQAEMALqees 1350
Cdd:PRK02224   236 RDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-------DDLLAEAGL---- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1351 vrrSERERRATLDQIATLERSLQATESELRASQEKIskmkaneTKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQR 1430
Cdd:PRK02224   305 ---DDADAEAVEARREELEDRDEELRDRLEECRVAA-------QAHNEEAESLREDADDLEERAEELREEAAELESELEE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1431 SRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA------- 1503
Cdd:PRK02224   375 AREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkc 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1504 --------------SLNSTQDKNLHLQKALTACEHDRQVLQERLDAArQALSEARKQSSSLGEQVQTLRGEVADLELQQV 1569
Cdd:PRK02224   455 pecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1570 EAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVER---SALRLEKDRVALRRTLD 1646
Cdd:PRK02224   534 EKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtLLAAIADAEDEIERLRE 613

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1622834693 1647 KVEREKLRSHEDTVRLSAEKGR---LDRTLTGAELELAEAQRQ 1686
Cdd:PRK02224   614 KREALAELNDERRERLAEKRERkreLEAEFDEARIEEAREDKE 656
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
348-889 2.75e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 2.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  348 EDAQREVQRLRSANELLSREKSNLAHsLQVAQQQAEELRQEREKLQAAQEELRRQRD-RLEEEQEDAVQDGARVRRELER 426
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIEL-LEPIRELAERYAAARERLAELEYLRAALRLwFAQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  427 SHRQLEQLEGKRSVLAKELVEVREALSRATLQR-DMLQAEKAEVAEALTKAEAGRVELElsmTKLRAEEASLQDSLSKLS 505
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLE---ALLAALGLPLPASAEEFA 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  506 ALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELR----LEQEVARQGLEGSLRVAEQA---- 577
Cdd:COG4913    384 ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAElpfv 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  578 -------------QEVLEQQLPTLR--------------------HERSRLQEQLAQLSRQLSGREQELEQ--------- 615
Cdd:COG4913    464 gelievrpeeerwRGAIERVLGGFAltllvppehyaaalrwvnrlHLRGRLVYERVRTGLPDPERPRLDPDslagkldfk 543

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  616 ---ARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGslFEVQRQLAQLEARREH 692
Cdd:COG4913    544 phpFRAWLEAELGRRFDYVCVDSPEELRRHPRAITRAGQVKGNGTRHEKDDRRRIRSRYVLG--FDNRAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  693 LEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQ--------------ASLREQRAAHEEDL 758
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELeaelerldassddlAALEEQLEELEAEL 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  759 QRLQREKEAAWRELEAERAQLQsQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALS 838
Cdd:COG4913    702 EELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRA 780

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622834693  839 EklmgtrhsLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEE 889
Cdd:COG4913    781 R--------LNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDR 823
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 574-1118 5.61e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 5.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  574 AEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAglavqlAAAER 653
Cdd:TIGR00618  210 TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAV------LEETQ 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  654 EGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaketLTGELAGLRQQIIAIQEKASLDKELMA 733
Cdd:TIGR00618  284 ERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL----------LMKRAAHVKQQSSIEEQRRLLQTLHSQ 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  734 QKLVQAEREAQASLREQRAAHEEDLQRL--QREKEAAWRELEAERAQLQSQLQREQEELLARLeaekeelseeiatlQQE 811
Cdd:TIGR00618  354 EIHIRDAHEVATSIREISCQQHTLTQHIhtLQQQKTTLTQKLQSLCKELDILQREQATIDTRT--------------SAF 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  812 RDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAV 891
Cdd:TIGR00618  420 RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLEL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  892 AAHAQEVR------------------------RLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKL 947
Cdd:TIGR00618  500 QEEPCPLCgscihpnparqdidnpgpltrrmqRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  948 RESQEGREVQRQEAGELRRSLGEGAKEREALR-RSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGE 1026
Cdd:TIGR00618  580 NRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAcEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQER 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1027 LRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ 1106
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARED 739

                          570
                   ....*....|..
gi 1622834693 1107 ELQVAQRKLQEQ 1118
Cdd:TIGR00618  740 ALNQSLKELMHQ 751
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 305-873 6.60e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.34  E-value: 6.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  305 YEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSReksnlahSLQVAQQQAEE 384
Cdd:pfam05483  221 HEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDE-------NLKELIEKKDH 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  385 LRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRaTLQRDMLQA 464
Cdd:pfam05483  294 LTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE-LLRTEQQRL 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  465 EKAEVAEALTKAEAGRVELELS-MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEA 543
Cdd:pfam05483  373 EKNEDQLKIITMELQKKSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEI 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  544 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQR- 622
Cdd:pfam05483  453 HDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERm 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  623 --QMEALERAARE--------KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREH 692
Cdd:pfam05483  533 lkQIENLEEKEMNlrdelesvREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEE 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  693 LEAEGQALllaKETLTGELAGLRQQIIAIQeKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwrel 772
Cdd:pfam05483  613 LHQENKAL---KKKGSAENKQLNAYEIKVN-KLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIA---- 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  773 eAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEklmgTRHSLATI- 851
Cdd:pfam05483  685 -DEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSN----IKAELLSLk 759

                          570       580
                   ....*....|....*....|...
gi 1622834693  852 -SLEMERQKRDAQSRQEQDRSTV 873
Cdd:pfam05483  760 kQLEIEKEEKEKLKMEAKENTAI 782
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 5-602 7.07e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 7.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693    5 QLDQAGLANQALSEDIRKVTSDWARSRKELEQREAAWRREEEsfnayfsnEHSRLLLLWRQVVGFRRLVSEVKMFTERDL 84
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL--------ELEELELELEEAQAEEYELLAELARLEQDI 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693   85 LQLGGELARTSRAVQEaglgLSTGLRLAESRTEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTE 164
Cdd:COG1196    305 ARLEERRRELEERLEE----LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  165 LGLAVERLQKQNLEKDQVNKDLTEKLEALESLrLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASD 244
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEAL-LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  245 GSLRGLSGQRTpspprrsspgrgrsprrgpspacsdssTLALIHSALHKRQLQVQDMRGRYEASQDLlgtLRKQLSDSES 324
Cdd:COG1196    460 ALLELLAELLE---------------------------EAALLEAALAELLEELAEAAARLLLLLEA---EADYEGFLEG 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  325 ERRALEEQLQRLRDKTDGAMQAQEDAQREVQrlrsANELLSREKSNLAHSLQVAQQQAEELRQERE-KLQAAQEELRRQR 403
Cdd:COG1196    510 VKAALLLAGLRGLAGAVAVLIGVEAAYEAAL----EAALAAALQNIVVEDDEVAAAAIEYLKAAKAgRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  404 DRLEEEQEDAVQDGARVRRELErshrqLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 483
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASD-----LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  484 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVA 563
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1622834693  564 RQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQL 602
Cdd:COG1196    741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 596-843 8.47e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 8.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  596 QEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGS 675
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  676 LFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKasldkelmAQKLVQAEREAQASLREQRAAHE 755
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA--------RREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  756 EDLQRLQREKEaawrELEAERAQLQsQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKT 835
Cdd:COG4942    171 AERAELEALLA----ELEEERAALE-ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                   ....*...
gi 1622834693  836 ALSEKLMG 843
Cdd:COG4942    246 AGFAALKG 253
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1495-1710 8.54e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 8.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1495 TEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQ 1574
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1575 LQQLREVLRQ---------RQEGEAAALHMVQKLQDERRL--LQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRR 1643
Cdd:COG4942     99 LEAQKEELAEllralyrlgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622834693 1644 TLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA 1710
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 298-965 9.31e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.19  E-value: 9.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  298 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDG--AMQAQEDAQREVQRLRSANELLSR--------- 366
Cdd:COG3096    443 LAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEveRSQAWQTARELLRRYRSQQALAQRlqqlraqla 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  367 EKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELV 446
Cdd:COG3096    523 ELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAP 602

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  447 EVREALSRATLQRDMLQAE---KAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESlaqDKLDLNRL-- 521
Cdd:COG3096    603 AWLAAQDALERLREQSGEAladSQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQPGGA---EDPRLLALae 679

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  522 ----------------------------------VAQLEEEKAALQGRQRQAEQ----EATVAREEQERLEELRLEQEVA 563
Cdd:COG3096    680 rlggvllseiyddvtledapyfsalygparhaivVPDLSAVKEQLAGLEDCPEDlyliEGDPDSFDDSVFDAEELEDAVV 759

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  564 RQGLEGSLRVAEQAQEVL------EQQLPTLRHERSRLQEQLAQLSRqlsgreqeleqARRAAQRQMEALERAAREKEAL 637
Cdd:COG3096    760 VKLSDRQWRYSRFPEVPLfgraarEKRLEELRAERDELAEQYAKASF-----------DVQKLQRLHQAFSQFVGGHLAV 828

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  638 AKEraglavqlAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEA-EGQALLLAKETLTGELAGLRQ 716
Cdd:COG3096    829 AFA--------PDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKlLPQANLLADETLADRLEELRE 900

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  717 QIIAIQEkasldkelmAQKLVQAEREAQASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQrEQEELLARLEA 796
Cdd:COG3096    901 ELDAAQE---------AQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADYLQAKEQQRRLKQQIF-ALSEVVQRRPH 969

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  797 EKEELSEEIATLQQERDEGLllaesekQQALSLKESEKTALSEKLMGTRHSLATISLEMErqkrDAQSRQEQDRSTVNAL 876
Cdd:COG3096    970 FSYEDAVGLLGENSDLNEKL-------RARLEQAEEARREAREQLRQAQAQYSQYNQVLA----SLKSSRDAKQQTLQEL 1038

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  877 TSELRDLRAQL-EEAVAAHAQEVRRLQEQA-------QDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA----- 943
Cdd:COG3096   1039 EQELEELGVQAdAEAEERARIRRDELHEELsqnrsrrSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAkagwc 1118

                          730       740
                   ....*....|....*....|....*....
gi 1622834693  944 --QRKLRESQEGREVQR-----QEAGELR 965
Cdd:COG3096   1119 avLRLARDNDVERRLHRrelayLSADELR 1147
mukB PRK04863
chromosome partition protein MukB;
324-1019 9.77e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.19  E-value: 9.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  324 SERRALEEQLQRLRdktdgamQAQEDAQREVQRLRSANELLSReksnlahslqvAQQQAEELRQEREKLQAAQEELRRQR 403
Cdd:PRK04863   506 REQRHLAEQLQQLR-------MRLSELEQRLRQQQRAERLLAE-----------FCKRLGKNLDDEDELEQLQEELEARL 567

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  404 DRLEEEQEDAVQDGARVRRELErshrQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 483
Cdd:PRK04863   568 ESLSESVSEARERRMALRQQLE----QLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLEREREL 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  484 ELSMTKLRAEEASLQDSLSKLSALNESLAQDkldLNRL------------------------------------VAQLEE 527
Cdd:PRK04863   644 TVERDELAARKQALDEEIERLSQPGGSEDPR---LNALaerfggvllseiyddvsledapyfsalygparhaivVPDLSD 720

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  528 EKAALQGRQRQAEQ----EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVL------EQQLPTLRHERSRLQE 597
Cdd:PRK04863   721 AAEQLAGLEDCPEDlyliEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFPEVPLfgraarEKRIEQLRAEREELAE 800

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  598 QLAQLSRQlsgreqeleqaRRAAQRQMEALERAAREKEALAKErAGLAVQLAAAEREGRTLSEEATRLRLEkealegslf 677
Cdd:PRK04863   801 RYATLSFD-----------VQKLQRLHQAFSRFIGSHLAVAFE-ADPEAELRQLNRRRVELERALADHESQ--------- 859

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  678 eVQRQLAQLEARREHLEA----EGQALLLAKETLTGELAGLRQQIIAIQE-KASLDKElmAQKLVQAEREAqASLREQra 752
Cdd:PRK04863   860 -EQQQRSQLEQAKEGLSAlnrlLPRLNLLADETLADRVEEIREQLDEAEEaKRFVQQH--GNALAQLEPIV-SVLQSD-- 933

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  753 ahEEDLQRLQREKEAAwrelEAERAQLQSQLqREQEELLARLEAEKEELSEEIATLQQERDEGLllaesekQQALSLKES 832
Cdd:PRK04863   934 --PEQFEQLKQDYQQA----QQTQRDAKQQA-FALTEVVQRRAHFSYEDAAEMLAKNSDLNEKL-------RQRLEQAEQ 999

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  833 EKTALSEKLMGTRHSLAtislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAhaqevrRLQEQAQDLGKQR 912
Cdd:PRK04863  1000 ERTRAREQLRQAQAQLA----QYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEE------RARARRDELHARL 1069

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  913 DSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRR-----SNEELRA 987
Cdd:PRK04863  1070 SANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRelaylSADELRS 1149

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 1622834693  988 AVKKAESeriSLKLA---NEDKEQKLALLEEARTA 1019
Cdd:PRK04863  1150 MSDKALG---ALRLAvadNEHLRDVLRLSEDPKRP 1181
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1360-1584 1.33e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1360 ATLDQIATLERSLQATE---------SELRASQEKISKMKANETKLEGDKRRLKevLDASESRTVKLELQRRSLEGELQR 1430
Cdd:COG4913    229 ALVEHFDDLERAHEALEdareqiellEPIRELAERYAAARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAELAR 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1431 SRLGLSDREAQAQALQDRVDSLQRQVADSEVKA-GTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQ 1509
Cdd:COG4913    307 LEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALR 386

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693 1510 DknlhlqkaltACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQ 1584
Cdd:COG4913    387 A----------EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
354-792 1.71e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 1.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  354 VQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQ 433
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  434 LEgkrsvLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL----QDSLSKLSALNE 509
Cdd:COG4717    128 LP-----LYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  510 SLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVA---------------RQGLEGSLRVA 574
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAallallglggsllslILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  575 EQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAERE 654
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  655 GRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEaegqALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQ 734
Cdd:COG4717    363 LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKE----ELEELEEQLEELLGELEELLEALDEEELEEELEELE 438

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693  735 KLVQAEREAQASLREQRAAHEEDLQRLQREKEAAwrELEAERAQLQSQLQREQEELLA 792
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLEEDGELA--ELLQELEELKAELRELAEEWAA 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1395-1633 2.12e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1395 KLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLN 1474
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1475 GALAKVeesegalrdkVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQV 1554
Cdd:COG4942    104 EELAEL----------LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1555 QTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALR 1633
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 482-1172 2.20e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 2.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  482 ELELSMTKLRAEEASLQDSlSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELrleqe 561
Cdd:pfam12128  257 ELRLSHLHFGYKSDETLIA-SRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQ----- 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  562 vARQGLEGSLRVAEQAQEvleqQLPTLRHERSRLQEQLAQLSRQLSGREQELEqaRRAAQRQMEALERAAREKEALAKER 641
Cdd:pfam12128  331 -HGAFLDADIETAAADQE----QLPSWQSELENLEERLKALTGKHQDVTAKYN--RRRSKIKEQNNRDIAGIKDKLAKIR 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  642 AGLAVQLAAAEREGRTLSEEAtrlrleKEALEGSLFEVQRQLAQLEARREHLEaegqaLLLAKETLTGElagLRQQIIAI 721
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRLGELK-----LRLNQATATPE---LLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKasLDKELMAQKLVQAERE-AQASLREQRAAHEEDLQRLQREkEAAWRELEAERAQLQSQLQREQEELLARLEAEKEE 800
Cdd:pfam12128  470 DER--IERAREEQEAANAEVErLQSELRQARKRRDQASEALRQA-SRRLEERQSALDELELQLFPQAGTLLHFLRKEAPD 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  801 LSEEIATLqqerdeglllaeseKQQALSLKESEKTALSEKLMGTRHSLATISLEMERqkrdaqsrqeQDRSTVNALTSEL 880
Cdd:pfam12128  547 WEQSIGKV--------------ISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKR----------IDVPEWAASEEEL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  881 RDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQlrlLEDARDGLRRELLEAQRKLRESQEGREVQRQE 960
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTA---LKNARLDLRRLFDEKQSEKDKKNKALAERKDS 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  961 AGELRRSLgegAKEREALRRSNEELRAAVKKAESErislklANEDKEQKLALLEEARTAvgkeagELRTGLQEVERSRLE 1040
Cdd:pfam12128  680 ANERLNSL---EAQLKQLDKKHQAWLEEQKEQKRE------ARTEKQAYWQVVEGALDA------QLALLKAAIAARRSG 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1041 ARRELQELRRQMKM------LDSEN-TRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQR 1113
Cdd:pfam12128  745 AKAELKALETWYKRdlaslgVDPDViAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1114 KLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAE 1172
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQ 883
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
408-1053 2.38e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 2.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  408 EEQEDAVQDGARVRRELERSHRQLEQLegkrsvlakelvevreaLSRATLQRDMLQAEKAEVAEALTKAEagrvELELSM 487
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKF-----------------IKRTENIEELIKEKEKELEEVLREIN----EISSEL 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  488 TKLRAEEASLQDSLSKLSALNESLAQdkldLNRLVAQLEEEKAALQGRQRQAEQEatvareeqerleelrleqevaRQGL 567
Cdd:PRK03918   217 PELREELEKLEKEVKELEELKEEIEE----LEKELESLEGSKRKLEEKIRELEER---------------------IEEL 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  568 EGSLRV-AEQAQEVLEQQLPTLRHER-SRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLA 645
Cdd:PRK03918   272 KKEIEElEEKVKELKELKEKAEEYIKlSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  646 VQLAAAEREGRTLsEEATRL-----RLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaKETLTGELAGLRqqiia 720
Cdd:PRK03918   352 KRLEELEERHELY-EEAKAKkeeleRLKKRLTGLTPEKLEKELEELEKAKEEIEEE-------ISKITARIGELK----- 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  721 iQEKASLDKELMaqKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELlarleAEKEE 800
Cdd:PRK03918   419 -KEIKELKKAIE--ELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELREL-----EKVLK 490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  801 LSEEIATLQQERDEglLLAESEKQQALSLKESEKTAlsEKLMGTRHSLATISLEMERQKRDAQSRQEqdrstvnaLTSEL 880
Cdd:PRK03918   491 KESELIKLKELAEQ--LKELEEKLKKYNLEELEKKA--EEYEKLKEKLIKLKGEIKSLKKELEKLEE--------LKKKL 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  881 RDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELleaqRKLRESQEGREVQRQE 960
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE----KELKKLEEELDKAFEE 634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  961 AGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANedKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLE 1040
Cdd:PRK03918   635 LAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAG--LRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712

                          650
                   ....*....|....*....
gi 1622834693 1041 ------ARRELQELRRQMK 1053
Cdd:PRK03918   713 leklekALERVEELREKVK 731
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 856-1074 2.98e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  856 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQL---EEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDA 932
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLaalERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  933 rdgLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL 1012
Cdd:COG4942    106 ---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1013 LEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA 1074
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
312-585 3.36e-06

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 51.44  E-value: 3.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  312 LGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREK 391
Cdd:COG4372     40 LDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEE 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  392 LQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAE 471
Cdd:COG4372    120 LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKE 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  472 ALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQE 551
Cdd:COG4372    200 EELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELE 279

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1622834693  552 RLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQL 585
Cdd:COG4372    280 IAALELEALEEAALELKLLALLLNLAALSLIGAL 313
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 314-870 3.37e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 3.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  314 TLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQ 393
Cdd:TIGR00618  271 ELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTL 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  394 AAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR--------EALSRATLQRDMLQAE 465
Cdd:TIGR00618  351 HSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQreqatidtRTSAFRDLQGQLAHAK 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  466 KAEVAEaLTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNR----------LVAQLEEEKAALQGR 535
Cdd:TIGR00618  431 KQQELQ-QRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQetrkkavvlaRLLELQEEPCPLCGS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  536 QRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQ------QLPTLRHERSRLQEQLAQLSRQLSGR 609
Cdd:TIGR00618  510 CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQraslkeQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  610 EQELEQARRAAQRQMEALERAARE--------KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQR 681
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEqhallrklQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRV 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  682 QLAQLEARREHLEAEGQALllaKETLTGELAGLRQQIIAIQEKASLDKEL--MAQKLVQAEREAQASLREQRAAHEEDLQ 759
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSE---KEQLTYWKEMLAQCQTLLRELETHIEEYdrEFNEIENASSSLGSDLAAREDALNQSLK 746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  760 RLQREKEAAWRELEAERAQLQ-------------SQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQA 826
Cdd:TIGR00618  747 ELMHQARTVLKARTEAHFNNNeevtaalqtgaelSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETL 826

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622834693  827 LSLKESEKTALsEKLMGTRHSLATISLEM-ERQKRDAQSRQEQDR 870
Cdd:TIGR00618  827 VQEEEQFLSRL-EEKSATLGEITHQLLKYeECSKQLAQLTQEQAK 870
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 728-1062 3.38e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 3.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  728 DKELMAQKLVQAEREAQASLREQRAAHEE-DLQRLQREKEAAWRELEAERAQLQSQLQREQEellarlEAEKEELSEEIA 806
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERRRKLEEAEKARQAE------MDRQAAIYAEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  807 TLQQERDEGLLLAESEKQQalslKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDlraq 886
Cdd:pfam17380  341 RMAMERERELERIRQEERK----RELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQ---- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  887 leeavaahaqevRRLQEQAQDLGKQRdsclREAEELRT-QLRLLEDARDglrRELLEAQRKLRESQEGREVQRQEAGELR 965
Cdd:pfam17380  413 ------------RKIQQQKVEMEQIR----AEQEEARQrEVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERK 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  966 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL-LEEARTAVGKEAGELRTGLQEVERSRLEARRE 1044
Cdd:pfam17380  474 RKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKeMEERQKAIYEEERRREAEEERRKQQEMEERRR 553

                          330
                   ....*....|....*...
gi 1622834693 1045 LQElrrQMKMLDSENTRL 1062
Cdd:pfam17380  554 IQE---QMRKATEERSRL 568
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
389-814 4.01e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 4.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  389 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAe 468
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  469 vaealtkaeagrvelelsmtklraeeasLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVARE 548
Cdd:COG4717    127 ----------------------------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEE 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  549 EQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSgREQELEQARRAAQRQMEALE 628
Cdd:COG4717    179 LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE-AAALEERLKEARLLLLIAAA 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  629 RAAREKEALAKERAGLAVQLAAAEREGrTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLT 708
Cdd:COG4717    258 LLALLGLGGSLLSLILTIAGVLFLVLG-LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSP 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  709 GELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE 788
Cdd:COG4717    337 EELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLG 416

                          410       420
                   ....*....|....*....|....*..
gi 1622834693  789 ELLARLEAEKEEL-SEEIATLQQERDE 814
Cdd:COG4717    417 ELEELLEALDEEElEEELEELEEELEE 443
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 315-615 4.57e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.56  E-value: 4.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  315 LRKQLSDSESERRALEEQLQRLRDKTdgamqaqEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQA 394
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEEKQNEI-------EKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  395 AQEELRRQRDRLEEEQEDAVQDGARVRRE----------LERSHRQLEQ----LEGKRSVLAKELVEVREALSRATLQRD 460
Cdd:TIGR04523  420 EKELLEKEIERLKETIIKNNSEIKDLTNQdsvkeliiknLDNTRESLETqlkvLSRSINKIKQNLEQKQKELKSKEKELK 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  461 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQdslSKLSALNESLAQDKLDLNRlvAQLEEEKAALQGRQRQAE 540
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKE---SKISDLEDELNKDDFELKK--ENLEKEIDEKNKEIEELK 574

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693  541 QEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQ 615
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 312-891 4.58e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.76  E-value: 4.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  312 LGTLRKQLSDSESERRALEEQLQRLRDktDGAMQAQEDAQREVQrLRSANELLSREKSNLAHSLQVAQQQAEELRQEREK 391
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRRRSKIKE 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  392 LQAAqeELRRQRDRLEEEQEDAVQDGARVRRELERSHRQL-EQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKaeva 470
Cdd:pfam12128  387 QNNR--DIAGIKDKLAKIREARDRQLAVAEDDLQALESELrEQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP---- 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  471 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEA------- 543
Cdd:pfam12128  461 ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAgtllhfl 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  544 -TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE------------------------------VLEQQLPTLRHER 592
Cdd:pfam12128  541 rKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGElnlygvkldlkridvpewaaseeelrerldKAEEALQSAREKQ 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  593 SRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALA-KERAGLAVQLAAAEREGRTLSEEATRLRLEKEA 671
Cdd:pfam12128  621 AAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKdKKNKALAERKDSANERLNSLEAQLKQLDKKHQA 700

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  672 LEGSLFEVQRQL--AQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQE--KASLDK----ELMAQKLVQAEREA 743
Cdd:pfam12128  701 WLEEQKEQKREArtEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETwyKRDLASlgvdPDVIAKLKREIRTL 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  744 QASLrEQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDeglllaESEK 823
Cdd:pfam12128  781 ERKI-ERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERK------ASEK 853

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693  824 QQALslkesektaLSEKLMGTRHSLATISlemeRQKRDAQSRQEQ-DRSTVNALTSELRDLRAQLEEAV 891
Cdd:pfam12128  854 QQVR---------LSENLRGLRCEMSKLA----TLKEDANSEQAQgSIGERLAQLEDLKLKRDYLSESV 909
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 878-1114 4.60e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 4.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  878 SELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 957
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  958 RQEAGELrrslgegakerealrrsneeLRAAVKKAESERISLKLANEDKEQ---KLALLEEARTAVGKEAGELRTGLQEV 1034
Cdd:COG4942    103 KEELAEL--------------------LRALYRLGRQPPLALLLSPEDFLDavrRLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1035 ERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK 1114
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
854-1187 6.99e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 6.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  854 EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEaVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDAR 933
Cdd:PRK03918   190 NIEELIKEKEKELEEVLREINEISSELPELREELEK-LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERI 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  934 DGLRRELLEAQRKLRESQEGREVQRQ--EAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERislklanEDKEQKLA 1011
Cdd:PRK03918   269 EELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-------EEKEERLE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1012 LLEEARTAVGKEAGELRTGLQEVERSRL------------------EARRELQELRRQMKMLDSENTRLGRELAELQGRL 1073
Cdd:PRK03918   342 ELKKKLKELEKRLEELEERHELYEEAKAkkeelerlkkrltgltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEI 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1074 ALGERA--EKESRRETLGLRQRLLKGEASLEVMRQ------ELQVAQRKLQEQEGEFRTRERRLLGSLEEARG--TEKQQ 1143
Cdd:PRK03918   422 KELKKAieELKKAKGKCPVCGRELTEEHRKELLEEytaelkRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKEL 501

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1144 LDHARGLELKLEATRAEAAE--------LGLRLSAAEGRAQGLEAELARVEA 1187
Cdd:PRK03918   502 AEQLKELEEKLKKYNLEELEkkaeeyekLKEKLIKLKGEIKSLKKELEKLEE 553
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 638-994 7.98e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.11  E-value: 7.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  638 AKERAGLAVQLAAAEREgrtLSEEATRLRLEKEALEgslfEVQRQLAQLEARREHLEAEGQAlllAKETLTGELAGLRQQ 717
Cdd:COG3096    277 ANERRELSERALELRRE---LFGARRQLAEEQYRLV----EMARELEELSARESDLEQDYQA---ASDHLNLVQTALRQQ 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  718 --IIAIQEK-ASLDKELMAQKLVQAER-EAQASLREQRAAHEEDLQRLQREKEAAWRELEAE--RA-QLQSQLQR--EQE 788
Cdd:COG3096    347 ekIERYQEDlEELTERLEEQEEVVEEAaEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQqtRAiQYQQAVQAleKAR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  789 ELLARLEAEKEELSEEIATLQ---QERDEGLLLAEsekqQALSLKESEKTALSEKLmgtrHSLATISLEMERQKRDAQSR 865
Cdd:COG3096    427 ALCGLPDLTPENAEDYLAAFRakeQQATEEVLELE----QKLSVADAARRQFEKAY----ELVCKIAGEVERSQAWQTAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  866 Q--EQDRSTVnALTSELRDLRAQLEEAVAAHAQEvRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 943
Cdd:COG3096    499 EllRRYRSQQ-ALAQRLQQLRAQLAELEQRLRQQ-QNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEA 576

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622834693  944 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAES 994
Cdd:COG3096    577 VEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQE 627
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
290-717 1.03e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  290 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREvQRLRSANELLSREKS 369
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE-AELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  370 NLAhSLQVAQQQAEELRQEREKLQAAQEELRRQRD--------RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVL 441
Cdd:COG4717    154 RLE-ELRELEEELEELEAELAELQEELEELLEQLSlateeelqDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  442 AKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRL 521
Cdd:COG4717    233 ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  522 VAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARqglEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQ 601
Cdd:COG4717    313 LEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE---AEELEEELQLEELEQEIAALLAEAGVEDEEELRA 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  602 LSRQLSgREQELEQARRAAQRQMEALERAARE------KEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALE-- 673
Cdd:COG4717    390 ALEQAE-EYQELKEELEELEEQLEELLGELEEllealdEEELEEELEELEEELEELEEELEELREELAELEAELEQLEed 468

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1622834693  674 GSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQ 717
Cdd:COG4717    469 GELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 564-793 1.04e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  564 RQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsgreQELEQARRAAQRQMEALERAAREKEA-LAKERA 642
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI----RALEQELAALEAELAELEKEIAELRAeLEAQKE 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  643 GLAVQLAAAEREGRTLSEEatrlrlekealegsLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQ 722
Cdd:COG4942    105 ELAELLRALYRLGRQPPLA--------------LLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834693  723 EKASLDKELMAQKlvQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLAR 793
Cdd:COG4942    171 AERAELEALLAEL--EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 291-606 1.18e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  291 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSN 370
Cdd:TIGR04523  365 LEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  371 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQdgarvrrELERSHRQLEQLEGKRSVLAKELVEVRE 450
Cdd:TIGR04523  445 LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK-------ELKSKEKELKKLNEEKKELEEKVKDLTK 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  451 ALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTK--LRAEEASLQDSLSKLSALNESL--AQDKLDLnrLVAQLE 526
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKenLEKEIDEKNKEIEELKQTQKSLkkKQEEKQE--LIDQKE 595

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  527 EEKAALqgRQRQAEQEATVAReeqerleelrleqevarqgLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQL 606
Cdd:TIGR04523  596 KEKKDL--IKEIEEKEKKISS-------------------LEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 323-1195 1.20e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.56  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  323 ESERRALEEQLQRLRDKtdgamqaQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 402
Cdd:pfam01576    4 EEEMQAKEEELQKVKER-------QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  403 RDRLEeeqedavqdgARVRRELERShrqlEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE 482
Cdd:pfam01576   77 LHELE----------SRLEEEEERS----QQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILL 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  483 LELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQeatvareeqerleelrleqev 562
Cdd:pfam01576  143 LEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEK--------------------- 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  563 ARQGLEgslrvaeQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQA----------RRAAQRQMEALERAAR 632
Cdd:pfam01576  202 GRQELE-------KAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAAlarleeetaqKNNALKKIRELEAQIS 274

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  633 E-KEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQrqlaQLEARREhleaegQALLLAKETLTGEL 711
Cdd:pfam01576  275 ElQEDLESERA----ARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQ----ELRSKRE------QEVTELKKALEEET 340

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  712 AGLRQQIIAIQEKASLDKELMAQKLVQAEReAQASLREQRAAHEEDLQRLQREK---EAAWRELEAERAQLQSQLQ---- 784
Cdd:pfam01576  341 RSHEAQLQEMRQKHTQALEELTEQLEQAKR-NKANLEKAKQALESENAELQAELrtlQQAKQDSEHKRKKLEGQLQelqa 419

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  785 ------REQEELLARLEAEKEELSEEIATLQQERDEGLLLA-----------------ESEKQQALSLK------ESEKT 835
Cdd:pfam01576  420 rlseseRQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSkdvsslesqlqdtqellQEETRQKLNLStrlrqlEDERN 499

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  836 ALSEKL---MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNA-------LTSELRDLRAQLEEAVAAhaqeVRRLQEQA 905
Cdd:pfam01576  500 SLQEQLeeeEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAleegkkrLQRELEALTQQLEEKAAA----YDKLEKTK 575

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  906 QDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEEL 985
Cdd:pfam01576  576 NRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEEL 655

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  986 RAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRlgre 1065
Cdd:pfam01576  656 ERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFER---- 731

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1066 laELQGRLALGEraekeSRRETLGLRQRLLKGEASLEVMRQELQVAQRK-----LQEQEGEFRTRERRLLGSLEEARGTE 1140
Cdd:pfam01576  732 --DLQARDEQGE-----EKRRQLVKQVRELEAELEDERKQRAQAVAAKKkleldLKELEAQIDAANKGREEAVKQLKKLQ 804

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1141 KQQLDHARglelKLEATRAEAAELGLRLSAAEGRAQGLEAE-------LARVEAQRRAAEAQ 1195
Cdd:pfam01576  805 AQMKDLQR----ELEEARASRDEILAQSKESEKKLKNLEAEllqlqedLAASERARRQAQQE 862
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1440-1669 1.38e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1440 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKAL 1519
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1520 tacEHDRQVLQERLDAA----RQALSEARKQSSSLGEQVQTLR--GEVADLELQQVEAEGQLQQLREVLRQRQEGEAAAL 1593
Cdd:COG4942    100 ---EAQKEELAELLRALyrlgRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1594 H-MVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV--RLSAEKGRL 1669
Cdd:COG4942    177 EaLLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPaaGFAALKGKL 255
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 346-1063 1.82e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.97  E-value: 1.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  346 AQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQedavqdgaRVRRELE 425
Cdd:TIGR00618  192 LHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--------KKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  426 RSHRQLEQLEGkrsvLAKELVEVREALSRATlQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLraeeaslqdslSKLS 505
Cdd:TIGR00618  264 QLRARIEELRA----QEAVLEETQERINRAR-KAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSR-----------AKLL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  506 ALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEelrleqevarqgLEGSLRVAEQAQEVLEQQL 585
Cdd:TIGR00618  328 MKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT------------LTQHIHTLQQQKTTLTQKL 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  586 PTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRL 665
Cdd:TIGR00618  396 QSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  666 R---------LEKEALEGS-LFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELmaqk 735
Cdd:TIGR00618  476 QtkeqihlqeTRKKAVVLArLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL---- 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  736 lvQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEG 815
Cdd:TIGR00618  552 --TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  816 LLLAESEKQQALSLKESEKTALSEKLMGTR---HSLATISLEMER-QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAV 891
Cdd:TIGR00618  630 VRLHLQQCSQELALKLTALHALQLTLTQERvreHALSIRVLPKELlASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREL 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  892 AAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQ-LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGE 970
Cdd:TIGR00618  710 ETHIEEYDREFNEIENASSSLGSDLAAREDALNQsLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQF 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  971 GAKEREALRRSNEELRAAVK-KAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVErsrlEARRELQELR 1049
Cdd:TIGR00618  790 FNRLREEDTHLLKTLEAEIGqEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYE----ECSKQLAQLT 865

                          730
                   ....*....|....
gi 1622834693 1050 RQMKMLDSENTRLG 1063
Cdd:TIGR00618  866 QEQAKIIQLSDKLN 879
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 722-1061 1.83e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 49.74  E-value: 1.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKASLDKEL-MAQKLVQAEREAQASLREQRAAHEEdlqrlqREKEAAWRELEAERAQLQSQlQREQEELLARLEAEKEE 800
Cdd:pfam17380  303 QEKEEKAREVeRRRKLEEAEKARQAEMDRQAAIYAE------QERMAMERERELERIRQEER-KRELERIRQEEIAMEIS 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  801 LSEEIATLQQERdeglllaeseKQQALSLKESEKTALSEKLmgtrhslatisLEMERQKRDAQSRQEQDRstvnaltsel 880
Cdd:pfam17380  376 RMRELERLQMER----------QQKNERVRQELEAARKVKI-----------LEEERQRKIQQQKVEMEQ---------- 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  881 rdLRAQLEEavaAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR-- 958
Cdd:pfam17380  425 --IRAEQEE---ARQREVRRLEEERA---REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRki 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  959 --QEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISlklanEDKEQKLALLEEARtavgKEAGELRTGLQevER 1036
Cdd:pfam17380  497 leKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREA-----EEERRKQQEMEERR----RIQEQMRKATE--ER 565

                          330       340
                   ....*....|....*....|....*
gi 1622834693 1037 SRLEARRELQELRRQMKmlDSENTR 1061
Cdd:pfam17380  566 SRLEAMEREREMMRQIV--ESEKAR 588
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1268-1636 2.06e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 2.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1268 ETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1347
Cdd:PRK02224   331 EECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1348 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1427
Cdd:PRK02224   411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEE 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1428 LQR--SRL----GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRD---KVRGLTEAL 1498
Cdd:PRK02224   491 VEEveERLeraeDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREaaaEAEEEAEEA 570

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1499 AQSSASLNSTQDKN----------LHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQq 1568
Cdd:PRK02224   571 REEVAELNSKLAELkeriesleriRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIE- 649

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693 1569 vEAEGQLQQLREVLRQRQEgeaaalhMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEK 1636
Cdd:PRK02224   650 -EAREDKERAEEYLEQVEE-------KLDELREERDDLQAEIGAVENELEELEELRERREALENRVEA 709
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1531-1702 2.07e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1531 ERLDAARQALSEARKQSSSL------GEQVQTLRGEVADLE-----LQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKL 1599
Cdd:COG4913    235 DDLERAHEALEDAREQIELLepirelAERYAAARERLAELEylraaLRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1600 QDERRLLQERLGSLQRA--------LAQLEAEKREVERSALRLEKDRVALRRTLDKVE-----------REKLRSHEDTV 1660
Cdd:COG4913    315 EARLDALREELDELEAQirgnggdrLEQLEREIERLERELEERERRRARLEALLAALGlplpasaeefaALRAEAAALLE 394

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1622834693 1661 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHS 1702
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS 436
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1312-1551 2.26e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1312 ATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKA 1391
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1392 NETKLEGDKRRLKEVLdasESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVE 1471
Cdd:COG4942     91 EIAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1472 RLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG 1551
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1518-1738 2.91e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1518 ALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQ 1597
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1598 KLQDERRLLQERLGSLQRALAQLEAEKR-----------EVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK 1666
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYRLGRQPPlalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1667 GRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1738
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
290-416 3.25e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  290 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKS 369
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622834693  370 NLAHSL---QVAQQQAEELRQE-REKLQAAQEELRRQRDRLEEEQEDAVQD 416
Cdd:COG4913    745 LELRALleeRFAAALGDAVERElRENLEERIDALRARLNRAEEELERAMRA 795
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 323-1073 3.43e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.02  E-value: 3.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  323 ESERRALEEQLQRLRDKTDGAM----QAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEE 398
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALeeltEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  399 LRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRAtlqRDMLQAEKaevaealtkaea 478
Cdd:pfam01576  417 LQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDT---QELLQEET------------ 481

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  479 gRVELELSmTKLRAEEAslqdslsKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRL 558
Cdd:pfam01576  482 -RQKLNLS-TRLRQLED-------ERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  559 EQEVARQGLEGSLRVA---EQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAarekE 635
Cdd:pfam01576  553 ELEALTQQLEEKAAAYdklEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRA----E 628

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  636 ALAKERAGLAVQLAAAEREGRTLSEEATR----LRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGEL 711
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERtnkqLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  712 -----AGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWR-ELEAERAQLQSQL-- 783
Cdd:pfam01576  709 qatedAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKkKLELDLKELEAQIda 788

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  784 ----QREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLkESEKTALSEKLMGTrhslatislemERQK 859
Cdd:pfam01576  789 ankgREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNL-EAELLQLQEDLAAS-----------ERAR 856

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  860 RDAQSRQEQ-------DRSTVNALTSELRDLRA---QLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLL 929
Cdd:pfam01576  857 RQAQQERDEladeiasGASGKSALQDEKRRLEAriaQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKS 936

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  930 EDARDGLRRELLEAQRKLRE-SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQ 1008
Cdd:pfam01576  937 ESARQQLERQNKELKAKLQEmEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERR 1016

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693 1009 KLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRL 1073
Cdd:pfam01576 1017 HADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 274-513 3.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 3.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  274 PSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQRE 353
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  354 VQRLRSAnelLSREKSNLAHSLQVAQQQAeelRQEREKLQAAQEELRRQRDRLEEEQEDAVQDgarvRRELERSHRQLEQ 433
Cdd:COG4942     92 IAELRAE---LEAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVRRLQYLKYLAPAR----REQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  434 LEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 513
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
593-892 4.91e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.59  E-value: 4.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  593 SRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEAL 672
Cdd:COG4372     34 RKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEEL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  673 EGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRA 752
Cdd:COG4372    114 QEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEAN 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  753 AHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKES 832
Cdd:COG4372    194 RNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDT 273

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  833 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVA 892
Cdd:COG4372    274 EEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 589-1062 4.92e-05

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 48.20  E-value: 4.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  589 RHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAERE-GRTLSEEATRLRL 667
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEaEEALREQAELNRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  668 EKEALEGSLFEVQRQLAQLEARREhleaegqalllAKETLTGELAGLRQQI-IAIQEKASLDKELMAQKLVQAEREAQAS 746
Cdd:pfam05557   81 KKKYLEALNKKLNEKESQLADARE-----------VISCLKNELSELRRQIqRAELELQSTNSELEELQERLDLLKAKAS 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  747 LREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS---QLQREQEEL--LARLEAEKEELSEEIATLQQERDEGLLLAES 821
Cdd:pfam05557  150 EAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQdseIVKNSKSELarIPELEKELERLREHNKHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  822 ekqqalslKESEKTALsEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---------------------------VN 874
Cdd:pfam05557  230 --------VEDLKRKL-EREEKYREEAATLELEKEKLEQELQSWVKLAQDTglnlrspedlsrrieqlqqreivlkeeNS 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  875 ALTSELRDLRAQLEEAVaahaQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR 954
Cdd:pfam05557  301 SLTSSARQLEKARRELE----QELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSP 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  955 EvqrqeageLRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEeaRTAVGKEAGELRTGLQEV 1034
Cdd:pfam05557  377 Q--------LLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALR--QQESLADPSYSKEEVDSL 446

                          490       500
                   ....*....|....*....|....*...
gi 1622834693 1035 ERSRLEARRELQELRRQMKMLDSENTRL 1062
Cdd:pfam05557  447 RRKLETLELERQRLREQKNELEMELERR 474
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 342-594 5.17e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 5.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  342 GAMQAQEDAQREvqrlrsanellsreksnlahsLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVR 421
Cdd:COG4942     17 AQADAAAEAEAE---------------------LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  422 RELERSHRQLEQLEGKRSVLAKELVEVREALSR--ATLQRDMLQAEKAEV--AEALTKAEAGRVELELSMTKLRAEEASL 497
Cdd:COG4942     76 QELAALEAELAELEKEIAELRAELEAQKEELAEllRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  498 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQA 577
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235

                          250
                   ....*....|....*..
gi 1622834693  578 QEVLEQQLPTLRHERSR 594
Cdd:COG4942    236 AAAAAERTPAAGFAALK 252
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 579-1053 5.22e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.09  E-value: 5.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  579 EVLEQQLPTLRHERSRLQEQLAQLSRQLSGRE------QELEQARRAAQRQMEALERA----AREKEALAKERAGLAVQL 648
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLElllsnlKKKIQKNKSLESQISELKKQnnqlKDNIEKKQQEINEKTTEI 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  649 AAAEREGRTLSEEATRLR-------LEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKetLTGELAGLRQQIIAI 721
Cdd:TIGR04523  249 SNTQTQLNQLKDEQNKIKkqlsekqKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE--LKSELKNQEKKLEEI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKASLDKELMAQ---KLVQAEREAQ------ASLREQRAAHEEDLQRLQREKEAAWRE---LEAERAQLQSQLQrEQEE 789
Cdd:TIGR04523  327 QNQISQNNKIISQlneQISQLKKELTnsesenSEKQRELEEKQNEIEKLKKENQSYKQEiknLESQINDLESKIQ-NQEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  790 LLARLEAEKEELSEEIATLQQERDEglLLAESEKQQA----LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 865
Cdd:TIGR04523  406 LNQQKDEQIKKLQQEKELLEKEIER--LKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  866 QEQDRSTVNALTSELRDLRaqleeavaahaQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQR 945
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLN-----------EEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  946 KLRESQEGREVQrqeagELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAG 1025
Cdd:TIGR04523  553 ELKKENLEKEID-----EKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENE 627

                          490       500
                   ....*....|....*....|....*...
gi 1622834693 1026 ELRTGLQEVERSRLEARRELQELRRQMK 1053
Cdd:TIGR04523  628 KLSSIIKNIKSKKNKLKQEVKQIKETIK 655
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 332-1195 5.24e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.50  E-value: 5.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  332 QLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE--- 408
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEieh 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  409 ------EQEDAVQDGARVRRELERSHRQLEQLEGK----RSVLAKELVEVREALSRA---TLQRDMLQAEKAEVAEALTK 475
Cdd:TIGR00606  260 nlskimKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQLNDLYHNHQRTVREkerELVDCQRELEKLNKERRLLN 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  476 AEAGRVELELSMTKLRAEEASLQdSLSKLSALNESLAQDKLDLNRLVAQLEEE-----KAALQGRQRQAEQEATVAREEQ 550
Cdd:TIGR00606  340 QEKTELLVEQGRLQLQADRHQEH-IRARDSLIQSLATRLELDGFERGPFSERQiknfhTLVIERQEDEAKTAAQLCADLQ 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  551 ERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsgreqELEQARRAAQRQMEALERA 630
Cdd:TIGR00606  419 SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL-----ELDQELRKAERELSKAEKN 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  631 ArEKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREhLEAEGQALLLA------- 703
Cdd:TIGR00606  494 S-LTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRK-IKSRHSDELTSllgyfpn 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  704 KETLTGELAGLRQQIIAIQEK-ASLDKELMAQKLVQAE-REAQASLREQRAAHEE-------------DLQRLQREKEAA 768
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRlAKLNKELASLEQNKNHiNNELESKEEQLSSYEDklfdvcgsqdeesDLERLKEEIEKS 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  769 WRELEAERA-----------------------QLQSQLQREQEELLARLEA-------EKEELSEEIATLQQERDEGLLL 818
Cdd:TIGR00606  652 SKQRAMLAGatavysqfitqltdenqsccpvcQRVFQTEAELQEFISDLQSklrlapdKLKSTESELKKKEKRRDEMLGL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  819 AESeKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALT--SELRDLRAQLEEAVAAHAQ 896
Cdd:TIGR00606  732 APG-RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQ 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  897 EVRRLqeQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEgrevQRQEAGELRRSLGEGAKERE 976
Cdd:TIGR00606  811 QAAKL--QGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKS----KTNELKSEKLQIGTNLQRRQ 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  977 ALRRSNEELRAAVKkaeseriSLKLANEDKEQKLALLEEARTAVGKEAGELrtgLQEVERSRLEARRELQELRRQMKMLD 1056
Cdd:TIGR00606  885 QFEEQLVELSTEVQ-------SLIREIKDAKEQDSPLETFLEKDQQEKEEL---ISSKETSNKKAQDKVNDIKEKVKNIH 954

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1057 SENTRLGRELAELQGRLALGERAEKESRRETLG-LRQRLLKGEASLEVMRQELQVA-QRKLQEQEGEFRTRERRLLGSLE 1134
Cdd:TIGR00606  955 GYMKDIENKIQDGKDDYLKQKETELNTVNAQLEeCEKHQEKINEDMRLMRQDIDTQkIQERWLQDNLTLRKRENELKEVE 1034

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834693 1135 EARGTEKQQLDHARGLELKLEATRAEAA--ELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQ 1195
Cdd:TIGR00606 1035 EELKQHLKEMGQMQVLQMKQEHQKLEENidLIKRNHVLALGRQKGYEKEIKHFKKELREPQFR 1097
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1268-1754 5.44e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 5.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1268 ETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQ 1347
Cdd:TIGR02169  304 ASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAET 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1348 EESVRRSERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1427
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1428 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTV-----------ERLNGAL--------------AKVEE 1482
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraveevlkASIQGVHgtvaqlgsvgeryaTAIEV 543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1483 SEGALRDKVRGLTEALAQSSAS--------------LNSTQDKNLHLQK---------ALTACEHDRQ------------ 1527
Cdd:TIGR02169  544 AAGNRLNNVVVEDDAVAKEAIEllkrrkagratflpLNKMRDERRDLSIlsedgvigfAVDLVEFDPKyepafkyvfgdt 623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1528 VLQERLDAARQALSEARkqssslgeqVQTLRGEVadLELQQVEAEGQLQQLREVLRQRQEGEAAAL--HMVQKLQDERRL 1605
Cdd:TIGR02169  624 LVVEDIEAARRLMGKYR---------MVTLEGEL--FEKSGAMTGGSRAPRGGILFSRSEPAELQRlrERLEGLKRELSS 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1606 LQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQR 1685
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834693 1686 QIQQLEAQVVVLEQ--SHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAhRQRVRGLEEQV 1754
Cdd:TIGR02169  773 DLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL-EKEIQELQEQR 842
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1040-1623 5.91e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 5.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1040 EARRELQELRRQMKMLdSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGE-ASLEVMRQELQVAQRKLQEQ 1118
Cdd:COG4913    239 RAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1119 EGEFRTRERRLLGSLEEARGTEKQQLDHA-RGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLG 1197
Cdd:COG4913    318 LDALREELDELEAQIRGNGGDRLEQLEREiERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1198 GLRSALRRglglgrapspaprpvpgspARDAAaggsgdglsspsnlecspgsqppspgpatspappdldpetvRGALQEF 1277
Cdd:COG4913    398 EELEALEE-------------------ALAEA-----------------------------------------EAALRDL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1278 LQELRSAQRERDDLRTQTSALSHQLAEMEAE-RDHATLRARQLQKA-----VAESEEA-RRSVDGRLSGVQAEMALQEes 1350
Cdd:COG4913    418 RRELRELEAEIASLERRKSNIPARLLALRDAlAEALGLDEAELPFVgelieVRPEEERwRGAIERVLGGFALTLLVPP-- 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1351 vrrsererratlDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASES---RTVKLELQRRSL--- 1424
Cdd:COG4913    496 ------------EHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHpfrAWLEAELGRRFDyvc 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1425 ---EGELQR-----SRLGLSDREAQAQALQDRVDSLQRQV--ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGL 1494
Cdd:COG4913    564 vdsPEELRRhpraiTRAGQVKGNGTRHEKDDRRRIRSRYVlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDAL 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1495 TEALAQSSASLN---------STQDKNLHLQKALTACE---HDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVA 1562
Cdd:COG4913    644 QERREALQRLAEyswdeidvaSAEREIAELEAELERLDassDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE 723

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693 1563 DLELQQVEAEGQLQQL----REVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAE 1623
Cdd:COG4913    724 QAEEELDELQDRLEAAedlaRLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEE 788
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 618-794 6.15e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 6.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  618 RAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEG 697
Cdd:COG1579      3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  698 QALLLAKE--TLTGELAGLRQQIIAIQEKAsldKELMAQklVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 775
Cdd:COG1579     83 GNVRNNKEyeALQKEIESLKRRISDLEDEI---LELMER--IEELEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170
                   ....*....|....*....
gi 1622834693  776 RAQLQSQLQREQEELLARL 794
Cdd:COG1579    158 LEELEAEREELAAKIPPEL 176
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 121-790 7.23e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 7.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  121 EKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKA-DLSARVTELGLAVERLQKQNLEKDQVNK--DLTEKLEALESLR 197
Cdd:TIGR00618  227 ELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLkQLRARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIE 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  198 LQEQAAL-ETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASDGSLRGLSGQRTpspPRRSSPGRGRSPRRGPSP 276
Cdd:TIGR00618  307 QQAQRIHtELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVAT---SIREISCQQHTLTQHIHT 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  277 ACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQR 356
Cdd:TIGR00618  384 LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  357 LRSAnellSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGArvrrELERSHRQLEQLEG 436
Cdd:TIGR00618  464 SAQS----LKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDID----NPGPLTRRMQRGEQ 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  437 KRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAqdkL 516
Cdd:TIGR00618  536 TYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA---C 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  517 DLNRLVAQLEEEKAALQGR--QRQAEQEATVAREEQERLEELRLEQEVArqglEGSLRVAEQAQEVLEQQLPTLRHERSR 594
Cdd:TIGR00618  613 EQHALLRKLQPEQDLQDVRlhLQQCSQELALKLTALHALQLTLTQERVR----EHALSIRVLPKELLASRQLALQKMQSE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  595 LQeqlaqlsrQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRleKEALEG 674
Cdd:TIGR00618  689 KE--------QLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA--RTVLKA 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  675 SLFEVQRQ------LAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLR 748
Cdd:TIGR00618  759 RTEAHFNNneevtaALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLE 838

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 1622834693  749 EQRAAHEEdlQRLQREKEAAWRELEAERAQLQSQLQREQEEL 790
Cdd:TIGR00618  839 EKSATLGE--ITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 314-833 7.39e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 7.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  314 TLRKQLSDSESERRALEEQLQRLR---DKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQERE 390
Cdd:TIGR04523  163 DLKKQKEELENELNLLEKEKLNIQkniDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEIN 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  391 KLQAAQEELRRQRDRLEEEQEdavqdgaRVRRELERSHRQLEQLEGKRSVLAKELVEVREALSraTLQRDMLQAEKAEVA 470
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQN-------KIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS--DLNNQKEQDWNKELK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  471 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRlvaQLEEEKAALQGRQRQAE---QEATVAR 547
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQR---ELEEKQNEIEKLKKENQsykQEIKNLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  548 EEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGRE---QELEQARRAAQRQM 624
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEliiKNLDNTRESLETQL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  625 EALERAAREKEAlakeraglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaK 704
Cdd:TIGR04523  471 KVLSRSINKIKQ----------NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESE-------K 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  705 ETLTGELAGLRQQIIAIQE---KASLDKELMA--QKLVQAEREAQASLREQRAAhEEDLQRLQREKEAAWRELEaERAQL 779
Cdd:TIGR04523  534 KEKESKISDLEDELNKDDFelkKENLEKEIDEknKEIEELKQTQKSLKKKQEEK-QELIDQKEKEKKDLIKEIE-EKEKK 611

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622834693  780 QSQLQREQEELlarlEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESE 833
Cdd:TIGR04523  612 ISSLEKELEKA----KKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 465-1137 7.67e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 7.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  465 EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSA----LNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAE 540
Cdd:TIGR00618  185 EFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKelkhLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQ 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  541 QEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHE---RSRLQEQLAQLSRQLSGREQELEQAR 617
Cdd:TIGR00618  265 LRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTElqsKMRSRAKLLMKRAAHVKQQSSIEEQR 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  618 RAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREgRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARrehleaeg 697
Cdd:TIGR00618  345 RLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHI-HTLQQQKTTLTQKLQSLCKELDILQREQATIDTR-------- 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  698 qalLLAKETLTGELAGLRQQIIAIQEKASLdKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQR-----EKEAAWREL 772
Cdd:TIGR00618  416 ---TSAFRDLQGQLAHAKKQQELQQRYAEL-CAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTkeqihLQETRKKAV 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  773 EAERAQLQSQLQREQEELLARLEAEKEELSEEIATlqQERDEGLLLAESEKQQALSLKESEKTAlseklmgtrhslatis 852
Cdd:TIGR00618  492 VLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL--TRRMQRGEQTYAQLETSEEDVYHQLTS---------------- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  853 lEMERQKRDAQSRQEQDRSTVnaltselrdLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDsclreaeELRTQLRLLEDA 932
Cdd:TIGR00618  554 -ERKQRASLKEQMQEIQQSFS---------ILTQCDNRSKEDIPNLQNITVRLQDLTEKLS-------EAEDMLACEQHA 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  933 rdgLRRELLEAQRKLRESQEGREVQRQEAgelrrsLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLAL 1012
Cdd:TIGR00618  617 ---LLRKLQPEQDLQDVRLHLQQCSQELA------LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQS 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1013 LEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLalgERAEKESRRETLGLRQ 1092
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL---MHQARTVLKARTEAHF 764

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1622834693 1093 RLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEAR 1137
Cdd:TIGR00618  765 NNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIG 809
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1274-1613 8.49e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.20  E-value: 8.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1274 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1353
Cdd:pfam07888   47 LQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1354 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESrtvklelQRRSLEGELQRSRL 1433
Cdd:pfam07888  127 HEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE-------ELRSLSKEFQELRN 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1434 GLSDREAQAQALQDRVDSL-------QRQVADSEVKAGTLQLTVERLNGALAKVE------ESEGALRDKVRG-LTEALA 1499
Cdd:pfam07888  200 SLAQRDTQVLQLQDTITTLtqklttaHRKEAENEALLEELRSLQERLNASERKVEglgeelSSMAAQRDRTQAeLHQARL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1500 QSSASLNSTQDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLE-----------LQQ 1568
Cdd:pfam07888  280 QAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEvelgrekdcnrVQL 359

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1622834693 1569 VEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSL 1613
Cdd:pfam07888  360 SESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETV 404
mukB PRK04863
chromosome partition protein MukB;
649-1118 9.09e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 9.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  649 AAAEREGRTLSEEATRLRLEK-------EALEGSLFEVQRQLAQLEARREHLEAEGQAlllAKETLTGELAGLRQQIIAI 721
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELytsrrqlAAEQYRLVEMARELAELNEAESDLEQDYQA---ASDHLNLVQTALRQQEKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKASLDKelmaqklVQAEREAQASLREQraAHEEdLQRLQREKEAAwrelEAERAQLQSQLQREQEELlarleaekeel 801
Cdd:PRK04863   352 RYQADLEE-------LEERLEEQNEVVEE--ADEQ-QEENEARAEAA----EEEVDELKSQLADYQQAL----------- 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  802 seeiaTLQQERdeglllaESEKQQALSLKESEKTALSeklmgtrhsLATISLEmerqkrDAQSRQEQDRSTVNALTSELR 881
Cdd:PRK04863   407 -----DVQQTR-------AIQYQQAVQALERAKQLCG---------LPDLTAD------NAEDWLEEFQAKEQEATEELL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  882 DLRAQLEEAVAAHAQevrrLQEQAQDLGKQRDSCLREAEElrtqlrllEDARDGLRRelLEAQRKLRESQEGRevqRQEA 961
Cdd:PRK04863   460 SLEQKLSVAQAAHSQ----FEQAYQLVRKIAGEVSRSEAW--------DVARELLRR--LREQRHLAEQLQQL---RMRL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  962 GELRRSLgegakereALRRSNEELRAAVKKaeseRISLKLANEDKEQKLAlleeartavgKEAGELRTGLQEVERSRLEA 1041
Cdd:PRK04863   523 SELEQRL--------RQQQRAERLLAEFCK----RLGKNLDDEDELEQLQ----------EELEARLESLSESVSEARER 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1042 RRELQELRRQMKMLDSENTRLGRELAELQGRLA-LGER--AEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQ 1118
Cdd:PRK04863   581 RMALRQQLEQLQARIQRLAARAPAWLAAQDALArLREQsgEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEE 660
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 284-472 1.03e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  284 LALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLR----- 358
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKeelae 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  359 ------------SANELLSREKSN--------LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGA 418
Cdd:COG4942    109 llralyrlgrqpPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA 188

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622834693  419 RVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEA 472
Cdd:COG4942    189 ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG3899 COG3899
Predicted ATPase [General function prediction only];
597-1111 1.15e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 47.16  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  597 EQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSL 676
Cdd:COG3899    729 ERALELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEE 808

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  677 FEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEE 756
Cdd:COG3899    809 AYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAA 888

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  757 DLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTA 836
Cdd:COG3899    889 AAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAA 968

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  837 LSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCL 916
Cdd:COG3899    969 AAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAA 1048

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  917 REAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 996
Cdd:COG3899   1049 LAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAA 1128

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  997 ISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALG 1076
Cdd:COG3899   1129 ARAAAALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAA 1208

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 1622834693 1077 ERAEKESRRETLGLRQRLLKGEASLEVMRQELQVA 1111
Cdd:COG3899   1209 LLALALLALEAAALLLLLLLAALALAAALLALRLL 1243
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1285-1702 1.30e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1285 QRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERRATLDQ 1364
Cdd:pfam15921  418 RRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT 497

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1365 IATLERSLQATESELRASQEKISKMKA---------NETKLEGDKRRLKEvldaSESRTVKLELQRRSLEGELQRSRLG- 1434
Cdd:pfam15921  498 VSDLTASLQEKERAIEATNAEITKLRSrvdlklqelQHLKNEGDHLRNVQ----TECEALKLQMAEKDKVIEILRQQIEn 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1435 ----LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQD 1510
Cdd:pfam15921  574 mtqlVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQ 653

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1511 KNLHLQKALTACEHDRQVLQERLDAARQALseaRKQSsslgEQVQTLRGEvadLELQQVEAEGQLQQLREVLRQRQEGEA 1590
Cdd:pfam15921  654 ERDQLLNEVKTSRNELNSLSEDYEVLKRNF---RNKS----EEMETTTNK---LKMQLKSAQSELEQTRNTLKSMEGSDG 723

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1591 AALHMVQKLQDE---RR----LLQERLGSLQRALAQLEAEKR--EVERSALRLEKDRVALRRTLDKVEREKLRSHEDtvR 1661
Cdd:pfam15921  724 HAMKVAMGMQKQitaKRgqidALQSKIQFLEEAMTNANKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQER--R 801

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1622834693 1662 LSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHS 1702
Cdd:pfam15921  802 LKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHT 842
mukB PRK04863
chromosome partition protein MukB;
405-793 1.36e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  405 RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA-GRVEL 483
Cdd:PRK04863   276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKiERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  484 ELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATvAREEQERLEELRLEQE 561
Cdd:PRK04863   356 DLEELEERLEEQNevVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQ-AVQALERAKQLCGLPD 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  562 VARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQ------EQLAQLSRQLSGreqelEQARRAAQRQMEALERAAREKE 635
Cdd:PRK04863   435 LTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQaahsqfEQAYQLVRKIAG-----EVSRSEAWDVARELLRRLREQR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  636 ALAKERAGLAVQLAAAEREGRtLSEEATRLRLEKEALEGSLF----EVQRQLAQLEARREHLEAEGQALLLAKETLTGEL 711
Cdd:PRK04863   510 HLAEQLQQLRMRLSELEQRLR-QQQRAERLLAEFCKRLGKNLddedELEQLQEELEARLESLSESVSEARERRMALRQQL 588

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  712 AGLRQQIiaiqekasldKELMAQKLV-QAEREAQASLREQRAAHEEDLQRL------QREKEAAWRELEAERAQLQSQLQ 784
Cdd:PRK04863   589 EQLQARI----------QRLAARAPAwLAAQDALARLREQSGEEFEDSQDVteymqqLLERERELTVERDELAARKQALD 658


                   ....*....
gi 1622834693  785 REQEELLAR 793
Cdd:PRK04863   659 EEIERLSQP 667
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 290-542 1.36e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  290 ALHKRQLQVQDMRGRYEASQdlLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKS 369
Cdd:TIGR02169  773 DLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK 850

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  370 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEqedavqdgarvRRELErshRQLEQLEGKRSVLAKELVEVR 449
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE-----------RDELE---AQLRELERKIEELEAQIEKKR 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  450 EALSRATLQRDMLQAEKAEVaEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALN-------ESLAQDKLDLNRLV 522
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKEKR 995

                          250       260
                   ....*....|....*....|
gi 1622834693  523 AQLEEEKAALQGRQRQAEQE 542
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
mukB PRK04863
chromosome partition protein MukB;
1306-1699 1.43e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.87  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1306 EAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMalqeesvrrsererratldqiATLERSLQATESELRASQEK 1385
Cdd:PRK04863   278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMAREL---------------------AELNEAESDLEQDYQAASDH 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1386 ISKMKANETKLEGDKRRLKEVLDASEsrtvKLELQRRSLEGelqrSRLGLSDREAQAQALQDRVDSLQRQVAD------- 1458
Cdd:PRK04863   337 LNLVQTALRQQEKIERYQADLEELEE----RLEEQNEVVEE----ADEQQEENEARAEAAEEEVDELKSQLADyqqaldv 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1459 SEVKAGTLQLTVERLNGA----------LAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALT-----ACE 1523
Cdd:PRK04863   409 QQTRAIQYQQAVQALERAkqlcglpdltADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiAGE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1524 HDRQVLQerlDAARQALSEARKQsSSLGEQVQTLRGEVADLElQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDER 1603
Cdd:PRK04863   489 VSRSEAW---DVARELLRRLREQ-RHLAEQLQQLRMRLSELE-QRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEEL 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1604 RLLQERLGSLQRALAQ----LEAEKREVERSALRLEKDRVALRRTLDKVERekLRSH-----EDTVRLSAEKGRLDRTLT 1674
Cdd:PRK04863   564 EARLESLSESVSEARErrmaLRQQLEQLQARIQRLAARAPAWLAAQDALAR--LREQsgeefEDSQDVTEYMQQLLERER 641

                          410       420
                   ....*....|....*....|....*
gi 1622834693 1675 GAELELAEAQRQIQQLEAQVVVLEQ 1699
Cdd:PRK04863   642 ELTVERDELAARKQALDEEIERLSQ 666
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
383-838 1.46e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 46.44  E-value: 1.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  383 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVevreALSRATLQRDML 462
Cdd:COG5278     79 EPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALV----RSGEGKALMDEI 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  463 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQE 542
Cdd:COG5278    155 RARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALEL 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  543 ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQR 622
Cdd:COG5278    235 LAALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAA 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  623 QMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLL 702
Cdd:COG5278    315 AAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  703 AKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQ 782
Cdd:COG5278    395 IAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAAL 474

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834693  783 LQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALS 838
Cdd:COG5278    475 AALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1516-1742 1.58e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1516 QKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALhm 1595
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR-- 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1596 vQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTG 1675
Cdd:COG4942     97 -AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622834693 1676 AELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERA 1742
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 660-786 1.84e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.61  E-value: 1.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  660 EEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKetltgeLAGLRQQIIAIQEKASldkELMAQklVQA 739
Cdd:COG0542    397 EAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFER------LAELRDELAELEEELE---ALKAR--WEA 465

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1622834693  740 EREAQASLREQRAAHEEDLQRLQrEKEAAWRELEAERAQLQSQLQRE 786
Cdd:COG0542    466 EKELIEEIQELKEELEQRYGKIP-ELEKELAELEEELAELAPLLREE 511
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 329-691 1.87e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 1.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  329 LEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE 408
Cdd:pfam07888   36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  409 EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMT 488
Cdd:pfam07888  116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  489 KLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLE 568
Cdd:pfam07888  196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELH 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  569 GSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEA----LAKERAGL 644
Cdd:pfam07888  276 QARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKleveLGREKDCN 355

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1622834693  645 AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 691
Cdd:pfam07888  356 RVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 323-644 1.88e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  323 ESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQ 402
Cdd:pfam07888   72 ERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  403 RDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE 482
Cdd:pfam07888  152 LERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAE 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  483 LELSMTKLRAEEASLQDSLSKLSALNEslaqdklDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEV 562
Cdd:pfam07888  232 NEALLEELRSLQERLNASERKVEGLGE-------ELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQ 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  563 ARQGLEGSL-----RVAEQAQEVLEQQlPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEAL 637
Cdd:pfam07888  305 ERETLQQSAeadkdRIEKLSAELQRLE-ERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQL 383


                   ....*..
gi 1622834693  638 AKERAGL 644
Cdd:pfam07888  384 QAEKQEL 390
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 645-871 2.16e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  645 AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEK 724
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  725 ASLDKELMAQKLVQAEREAQASlREQRAAHEEDLQRLQReKEAAWRELEAERAQLQSQLQREQEEL---LARLEAEKEEL 801
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQP-PLALLLSPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAELaalRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  802 SEEIATLQQERDEgLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRS 871
Cdd:COG4942    177 EALLAELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
734-1200 2.34e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 2.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  734 QKLVQAEREAQASLREQRAAHEEDLQRLqREKEAAWRELEAERAQLQSQLQR--EQEELLARLEAEKEELSEEIATLQ-- 809
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREI-NEISSELPELREELEKLEKEVKEleELKEEIEELEKELESLEGSKRKLEek 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  810 ----QERDEGLLLAESE-KQQALSLKESEKTA-----LSEKLMGTRHSLATISLEMERQKRDAQSRQEQ------DRSTV 873
Cdd:PRK03918   261 irelEERIEELKKEIEElEEKVKELKELKEKAeeyikLSEFYEEYLDELREIEKRLSRLEEEINGIEERikeleeKEERL 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  874 NALTSELRDLRAQLEEAVAAHA--QEVRRLQEQAQDLGKQRDSclREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQ 951
Cdd:PRK03918   341 EELKKKLKELEKRLEELEERHElyEEAKAKKEELERLKKRLTG--LTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  952 EGREVQRQEAGELR----------RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVG 1021
Cdd:PRK03918   419 KEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1022 KEAGE----LRTGLQEVERSRLEAR-RELQELRRQMKMLDSENTRLGREL---AELQGRLALGERAEKESRRETLGLRQR 1093
Cdd:PRK03918   499 KELAEqlkeLEEKLKKYNLEELEKKaEEYEKLKEKLIKLKGEIKSLKKELeklEELKKKLAELEKKLDELEEELAELLKE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1094 LL----KGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLS 1169
Cdd:PRK03918   579 LEelgfESVEELEERLKELEPFYNEYLELKDA-EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1622834693 1170 AAEGRA------------QGLEAELARVEAQRRAAEAQLGGLR 1200
Cdd:PRK03918   658 EEEYEElreeylelsrelAGLRAELEELEKRREEIKKTLEKLK 700
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 722-939 3.11e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  722 QEKASLDKELMA-QKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQsQLQREQEELLARLEAEKEE 800
Cdd:COG4942     27 AELEQLQQEIAElEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  801 LSEEIATLQQ--ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDaqsrQEQDRSTVNALTS 878
Cdd:COG4942    106 LAELLRALYRlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE----LEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834693  879 ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRE 939
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 350-954 3.14e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.98  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  350 AQREVQRLRSANELLSREKSNLAHSLQVAQQQ---AEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELER 426
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQeerQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEA 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  427 SHRQLEQLEG----KRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE--------LELSMTKLRAE- 493
Cdd:pfam12128  327 LEDQHGAFLDadieTAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqnnrdiagIKDKLAKIREAr 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  494 ---EASLQDSLSKL-SALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQaeqeATVAREEQERLEELRLEQEVARQGLEG 569
Cdd:pfam12128  407 drqLAVAEDDLQALeSELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQ----ATATPELLLQLENFDERIERAREEQEA 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  570 SLRVAEQAQEVLEQqlptLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGlavQLA 649
Cdd:pfam12128  483 ANAEVERLQSELRQ----ARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIG---KVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  650 AAEREGRT-LSEEATRlrlEKEALEGSLFEVQRQLAQLEARREHleaegqallLAKETLTGELAGLRQQIIAIQEKASLD 728
Cdd:pfam12128  556 SPELLHRTdLDPEVWD---GSVGGELNLYGVKLDLKRIDVPEWA---------ASEEELRERLDKAEEALQSAREKQAAA 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  729 KELMAQKLVQAErEAQASLREQRAAHE---EDLQRLQREKEAAWRELEAERAQLQSQLQREqeelLARLEAEKEELSEEI 805
Cdd:pfam12128  624 EEQLVQANGELE-KASREETFARTALKnarLDLRRLFDEKQSEKDKKNKALAERKDSANER----LNSLEAQLKQLDKKH 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  806 ATLQQERDEGLLLAESEKQQALSLKESEKTA----LSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 881
Cdd:pfam12128  699 QAWLEEQKEQKREARTEKQAYWQVVEGALDAqlalLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIR 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  882 DLRAQLEEAvAAHAQEVRR----LQE----QAQDLGKQRDSCLREAEELRTQL-RLLEDARdgLRRELLEAQRKLRESQE 952
Cdd:pfam12128  779 TLERKIERI-AVRRQEVLRyfdwYQEtwlqRRPRLATQLSNIERAISELQQQLaRLIADTK--LRRAKLEMERKASEKQQ 855


                   ..
gi 1622834693  953 GR 954
Cdd:pfam12128  856 VR 857
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1278-1725 3.20e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 3.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1278 LQELRSAQRERDDLRTQTSALSHQLA----EMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1353
Cdd:COG3096    245 LEAIRVTQSDRDLFKHLITEATNYVAadymRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESD 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1354 SERERRATLDQIATLERSLQAteselrasQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRL 1433
Cdd:COG3096    325 LEQDYQAASDHLNLVQTALRQ--------QEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKS 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1434 GLSDREAQAQALQDRVDSLQRQV---ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNStQD 1510
Cdd:COG3096    397 QLADYQQALDVQQTRAIQYQQAVqalEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQ-FE 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1511 KNLHLQKALTAcEHDRQvlqERLDAARQALSEARKQSSsLGEQVQTLRGEVADLElQQVEAEGQLQQLREVLRQRQEGEA 1590
Cdd:COG3096    476 KAYELVCKIAG-EVERS---QAWQTARELLRRYRSQQA-LAQRLQQLRAQLAELE-QRLRQQQNAERLLEEFCQRIGQQL 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1591 AALHMVQKLQderrllqerlgslqralAQLEAEKREVERSALRLEKDRVALRRTLDKVE--REKLRSHEDTVRLSAEKGR 1668
Cdd:COG3096    550 DAAEELEELL-----------------AELEAQLEELEEQAAEAVEQRSELRQQLEQLRarIKELAARAPAWLAAQDALE 612

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693 1669 LDRTLTGAELE-LAEAQRQIQQLeaqvvvLEQSHSpAQLEVDAQQQQHLELQQEVERL 1725
Cdd:COG3096    613 RLREQSGEALAdSQEVTAAMQQL------LERERE-ATVERDELAARKQALESQIERL 663
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 290-636 3.35e-04

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 45.06  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  290 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKS 369
Cdd:pfam19220    7 LLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  370 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 449
Cdd:pfam19220   87 ELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATAR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  450 EALSRATLQRDMLQAEKAEVAEALTKAEAgrvelelsmtKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 529
Cdd:pfam19220  167 ERLALLEQENRRLQALSEEQAAELAELTR----------RLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAV 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  530 AALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLsgr 609
Cdd:pfam19220  237 EAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQF--- 313

                          330       340
                   ....*....|....*....|....*..
gi 1622834693  610 eQELEQARRAAQRQMEALERAAREKEA 636
Cdd:pfam19220  314 -QEMQRARAELEERAEMLTKALAAKDA 339
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
806-1239 3.53e-04

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 45.37  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  806 ATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRA 885
Cdd:COG5281     15 AAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAAALAEDAAAAAAA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  886 QLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELR 965
Cdd:COG5281     95 AEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALAAAAAAAAAAAAAAA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  966 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARREL 1045
Cdd:COG5281    175 AAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAASAAAQALAALAAAA 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1046 QELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQE--QEGEFR 1123
Cdd:COG5281    255 AAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAAAQALRAaaQALAAL 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1124 TRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQ----RRAAEAQLGGL 1199
Cdd:COG5281    335 AQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSATNVaaqvAQAATSAFSGL 414

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1622834693 1200 RSALRRGLGLGRAPSPAPRPVPGSPARDAAAGGSGDGLSS 1239
Cdd:COG5281    415 TDALAGAVTTGKLLFDALASSIASIADALANAALASAADA 454
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1360-1754 3.64e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1360 ATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDRE 1439
Cdd:PRK02224   234 ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1440 AQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKAL 1519
Cdd:PRK02224   314 ARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEI 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1520 TACEH-------DRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAdlELQQVEAEGQLQQLREVLRQRQEGEAAA 1592
Cdd:PRK02224   394 EELRErfgdapvDLGNAEDFLEELREERDELREREAELEATLRTARERVE--EAEALLEAGKCPECGQPVEGSPHVETIE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1593 --LHMVQKLQDERRLLQERLGSLQRALAQLEAEKrEVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLD 1670
Cdd:PRK02224   472 edRERVEELEAELEDLEEEVEEVEERLERAEDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1671 RTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA------QQQQHLELQQEVERLRSAQVQ-TERTLEARER-- 1741
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESlerirtLLAAIADAEDEIERLREKREAlAELNDERRERla 630

                          410
                   ....*....|...
gi 1622834693 1742 AHRQRVRGLEEQV 1754
Cdd:PRK02224   631 EKRERKRELEAEF 643
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 781-1189 3.70e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 3.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  781 SQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQ----QALSLKESEKTALSEKLMGTRHSLATISLEME 856
Cdd:pfam15921  223 SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQdrieQLISEHEVEITGLTEKASSARSQANSIQSQLE 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  857 RQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGL 936
Cdd:pfam15921  303 IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  937 RRELLEAQRKLR-ESQEGREVQRQEAG------ELRRSLGEGAKEREALRRSNEELRAAVK-KAESERISLKLANEDKEQ 1008
Cdd:pfam15921  383 LADLHKREKELSlEKEQNKRLWDRDTGnsitidHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEK 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1009 KLAL---LEEARTAVGKEAGEL---RTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR----ELAELQGRLALGER 1078
Cdd:pfam15921  463 VSSLtaqLESTKEMLRKVVEELtakKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSrvdlKLQELQHLKNEGDH 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1079 AeKESRRETLGLRQRLLKGEASLEVMRQELQvAQRKLQEQEGefrtrerRLLGSLEeargTEKQQldhargLELKLEATR 1158
Cdd:pfam15921  543 L-RNVQTECEALKLQMAEKDKVIEILRQQIE-NMTQLVGQHG-------RTAGAMQ----VEKAQ------LEKEINDRR 603

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1622834693 1159 AEAAELGLRLSAAEGRAQGLEAELARVEAQR 1189
Cdd:pfam15921  604 LELQEFKILKDKKDAKIRELEARVSDLELEK 634
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 382-1197 3.88e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 3.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  382 AEELRQEREKLQAAQEELRRQRDRLEEEQEdavqdgarvrrELERSHRQLEQLEGKRSVLAKELVEVREALSRatLQRDM 461
Cdd:COG3096    277 ANERRELSERALELRRELFGARRQLAEEQY-----------RLVEMARELEELSARESDLEQDYQAASDHLNL--VQTAL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  462 LQAEKAEVAEAltkaeagrvELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQ 541
Cdd:COG3096    344 RQQEKIERYQE---------DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQ 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  542 --EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE----VLEQQLPTLRHERSRLqEQLAQLSRQLSGreqelEQ 615
Cdd:COG3096    415 yqQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATeevlELEQKLSVADAARRQF-EKAYELVCKIAG-----EV 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  616 ARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLsEEATRLRLEKEALEG----SLFEVQRQLAQLEARRE 691
Cdd:COG3096    489 ERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQ-QNAERLLEEFCQRIGqqldAAEELEELLAELEAQLE 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  692 HLEAEgqalllaKETLTGELAGLRQQIIAIQEKAsldKELMAQKLV-QAEREAQASLREQRAAHEEDLQRLQrekEAAWR 770
Cdd:COG3096    568 ELEEQ-------AAEAVEQRSELRQQLEQLRARI---KELAARAPAwLAAQDALERLREQSGEALADSQEVT---AAMQQ 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  771 ELEAERA--QLQSQLQREQEELLARLEAEKEELSEEIATLQQ--ERDEGLLLAESEKQQALSlkesEKTALSEKLMGTRH 846
Cdd:COG3096    635 LLEREREatVERDELAARKQALESQIERLSQPGGAEDPRLLAlaERLGGVLLSEIYDDVTLE----DAPYFSALYGPARH 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  847 SLATISLEMERQK---------------RDAQS-------RQEQDRSTV---------------------NALTSELRDL 883
Cdd:COG3096    711 AIVVPDLSAVKEQlagledcpedlylieGDPDSfddsvfdAEELEDAVVvklsdrqwrysrfpevplfgrAAREKRLEEL 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  884 RAQLEEAVAAHAQ---EVRRLQEQAQD----LGKQRDSCLREAEElrTQLRLLEDARDGLRRELLEAQRKLRESQEGREV 956
Cdd:COG3096    791 RAERDELAEQYAKasfDVQKLQRLHQAfsqfVGGHLAVAFAPDPE--AELAALRQRRSELERELAQHRAQEQQLRQQLDQ 868

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  957 QRQEAGELRRSLGE-GAKEREALRRSNEELRAAVKKAESERISLKLanedKEQKLALLEEARTAVGKEAgelrTGLQEVE 1035
Cdd:COG3096    869 LKEQLQLLNKLLPQaNLLADETLADRLEELREELDAAQEAQAFIQQ----HGKALAQLEPLVAVLQSDP----EQFEQLQ 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1036 RSRLEARRELQELRRQMKMLDsentrlgrELAELQGRLALGERAEKESRRETLG--LRQRLLKGEASlevmRQELQVAQR 1113
Cdd:COG3096    941 ADYLQAKEQQRRLKQQIFALS--------EVVQRRPHFSYEDAVGLLGENSDLNekLRARLEQAEEA----RREAREQLR 1008

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1114 KLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAA-----ELGLRLSAAEGRAQGLEAELARVEAQ 1188
Cdd:COG3096   1009 QAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERArirrdELHEELSQNRSRRSQLEKQLTRCEAE 1088


                   ....*....
gi 1622834693 1189 RRAAEAQLG 1197
Cdd:COG3096   1089 MDSLQKRLR 1097
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 307-622 4.02e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 45.60  E-value: 4.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  307 ASQDLLGTLRKQLSDSESERRALEEQlqrlrdktdgaMQAQEDAQRevqrlrsanelLSREKSNLAHSLQVAQQQAEELR 386
Cdd:NF012221  1539 ESSQQADAVSKHAKQDDAAQNALADK-----------ERAEADRQR-----------LEQEKQQQLAAISGSQSQLESTD 1596

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  387 QereklQAAQEELRRQRDRLEEEQEDavqdgarVRRELERSHRQLEQLEGK-----------RSVLAKELVE-VREALSR 454
Cdd:NF012221  1597 Q-----NALETNGQAQRDAILEESRA-------VTKELTTLAQGLDALDSQatyagesgdqwRNPFAGGLLDrVQEQLDD 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  455 ATLQ--------RDMLQAEKAEVAEALTKAEAGRVELElsmtKLRAEeasLQDSLSKLSALNESLAQDKLDlNRLVAQLE 526
Cdd:NF012221  1665 AKKIsgkqladaKQRHVDNQQKVKDAVAKSEAGVAQGE----QNQAN---AEQDIDDAKADAEKRKDDALA-KQNEAQQA 1736

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  527 EEKA--ALQGRQRQAEQEATVAREEQERLEELRLEQEVA------RQGLEGSlRVAEQAQEVlEQQLPTLRHERSRLQEQ 598
Cdd:NF012221  1737 ESDAnaAANDAQSRGEQDASAAENKANQAQADAKGAKQDesdkpnRQGAAGS-GLSGKAYSV-EGVAEPGSHINPDSPAA 1814

                          330       340
                   ....*....|....*....|....*.
gi 1622834693  599 L-AQLSRQLSGREQE-LEQARRAAQR 622
Cdd:NF012221  1815 AdGRFSEGLTEQEQEaLEGATNAVNR 1840
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 582-992 4.50e-04

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 45.05  E-value: 4.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  582 EQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQArrAAQRQMEALERAAREK-EALAKERAGLAVQLAAAEREGRTL-- 658
Cdd:pfam13166   95 QEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKL--EADFLDECWKKIKRKKnSALSEALNGFKYEANFKSRLLREIek 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  659 --SEEATRLRLEK-EALEGSLFEVQRQ-LAQLEAR-REHLEAEGQALLLAKETLTGelaglrqqiIAIQEkasLDKELMA 733
Cdd:pfam13166  173 dnFNAGVLLSDEDrKAALATVFSDNKPeIAPLTFNvIDFDALEKAEILIQKVIGKS---------SAIEE---LIKNPDL 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  734 QKLVQAEREAqaslreqraaHEEDL-------QRLQREKeaaWRELEA----ERAQLQSQLQREQEELLaRLEAEKEELS 802
Cdd:pfam13166  241 ADWVEQGLEL----------HKAHLdtcpfcgQPLPAER---KAALEAhfddEFTEFQNRLQKLIEKVE-SAISSLLAQL 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  803 EEIATLQQERDEglllAESEKQQALSLKEsektALSEKLMGTRHslatislEMERQKRDAQSRQEQDRSTvnALTSELRD 882
Cdd:pfam13166  307 PAVSDLASLLSA----FELDVEDIESEAE----VLNSQLDGLRR-------ALEAKRKDPFKSIELDSVD--AKIESIND 369

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  883 LRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDscLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAG 962
Cdd:pfam13166  370 LVASINELIAKHNEITDNFEEEKNKAKKKLR--LHLVEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIK 447

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1622834693  963 ELRRSLG-------EGAKEREALRRSNEELRAAVKKA 992
Cdd:pfam13166  448 ELEAQLRdhkpgadEINKLLKAFGFGELELSFNEEGK 484
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 647-983 4.69e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 4.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  647 QLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalllaketlTGELAGLRQQ--IIAIQEK 724
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAE-----------KARQAEMDRQaaIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  725 ASLDKELMAQKLVQAEREAQ-ASLREQRAAHE----EDLQRLQREK----EAAWRELEAERAqlqsqlQREQEELLARLE 795
Cdd:pfam17380  342 MAMERERELERIRQEERKRElERIRQEEIAMEisrmRELERLQMERqqknERVRQELEAARK------VKILEEERQRKI 415

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  796 AEKEELSEEIATLQQE-RDEGLLLAESEKQQALS---LKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRS 871
Cdd:pfam17380  416 QQQKVEMEQIRAEQEEaRQREVRRLEEERAREMErvrLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRK 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  872 TVNALTSELRdlRAQLEEavaahaQEVRRLQEQAQDlgkQRDSCLREAEElrtqlrlledardglRRELLEAQRKLRESQ 951
Cdd:pfam17380  496 ILEKELEERK--QAMIEE------ERKRKLLEKEME---ERQKAIYEEER---------------RREAEEERRKQQEME 549

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1622834693  952 EGREVQRQ--EAGELRRSLGEGAKEREALRRSNE 983
Cdd:pfam17380  550 ERRRIQEQmrKATEERSRLEAMEREREMMRQIVE 583
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
745-1231 4.72e-04

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 44.99  E-value: 4.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  745 ASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQ 824
Cdd:COG5281      1 AAALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADAL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  825 QALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQ 904
Cdd:COG5281     81 AAALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  905 AQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 984
Cdd:COG5281    161 AAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAA 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  985 LRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR 1064
Cdd:COG5281    241 SAAAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAA 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1065 ELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEE----ARGTE 1140
Cdd:COG5281    321 AQALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEyadsATNVA 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1141 KQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPV 1220
Cdd:COG5281    401 AQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIADALANAALASAADALGGALAGALGGLFGGGGGAAAGAAVY 480

                          490
                   ....*....|.
gi 1622834693 1221 PGSPARDAAAG 1231
Cdd:COG5281    481 AGALGPFASGG 491
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 579-1203 4.78e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 4.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  579 EVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTL 658
Cdd:TIGR04523   78 KILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKL 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  659 SEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEgqalLLAKETLtgelaglrqqIIAIQEKASLDKELMAQKLvq 738
Cdd:TIGR04523  158 NNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK----LLKLELL----------LSNLKKKIQKNKSLESQIS-- 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  739 aereaqaSLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQsQLQREQEELLARLEAEkeelseeiaTLQQERDEGLLl 818
Cdd:TIGR04523  222 -------ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN-QLKDEQNKIKKQLSEK---------QKELEQNNKKI- 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  819 aeSEKQQALSLKESEKTAL-SEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQE 897
Cdd:TIGR04523  284 --KELEKQLNQLKSEISDLnNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEK 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  898 VRRLQE---QAQDLGKQRDSCLREAEELRTQLRLLEdardglrRELLEAQRKLRESQEGREVQRQEAGELRrslgegaKE 974
Cdd:TIGR04523  362 QRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLE-------SKIQNQEKLNQQKDEQIKKLQQEKELLE-------KE 427

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  975 REALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERsrlearrELQELRRQMKM 1054
Cdd:TIGR04523  428 IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK-------ELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1055 LDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRtrerrllgsLE 1134
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKE---------IE 571

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622834693 1135 EARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSAL 1203
Cdd:TIGR04523  572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKK 640
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 343-506 4.88e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 4.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  343 AMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVR- 421
Cdd:COG1579      1 AMPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEe 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  422 --------RELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAgrvELELSMTKLRAE 493
Cdd:COG1579     81 qlgnvrnnKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAE 157

                          170
                   ....*....|...
gi 1622834693  494 EASLQDSLSKLSA 506
Cdd:COG1579    158 LEELEAEREELAA 170
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
568-1014 6.32e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 44.51  E-value: 6.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  568 EGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALAK--ERAGLA 645
Cdd:COG5278     82 EEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEirARLLLL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  646 VQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKA 725
Cdd:COG5278    162 ALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALA 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  726 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEI 805
Cdd:COG5278    242 LALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAA 321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  806 ATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRA 885
Cdd:COG5278    322 AAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAA 401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  886 QLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELR 965
Cdd:COG5278    402 AAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAA 481

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1622834693  966 RSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLE 1014
Cdd:COG5278    482 AALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
291-695 6.36e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 6.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  291 LHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQR---LRDKTDGAMQAQEDAQREVQRLRSANELLSRe 367
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSR- 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  368 KSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEE---EQEDAVQDGARVRR-ELERSHRQLEQLEGKRSVLAK 443
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErheLYEEAKAKKEELERlKKRLTGLTPEKLEKELEELEK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  444 ELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEE---------ASLQDSLSKLSALNESLAQD 514
Cdd:PRK03918   399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkelleeytAELKRIEKELKEIEEKERKL 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  515 KLDLNRLVAQLEEEKAALQGRQ-----RQAEQEATVAREEQERLEELRLEQEVAR-QGLEGSLRVAE---QAQEVLEQQL 585
Cdd:PRK03918   479 RKELRELEKVLKKESELIKLKElaeqlKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIKSLKkelEKLEELKKKL 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  586 PTLRHERSRLQEQLAQLSRQLS-----------GREQELE-------QARRAAQRQMEALERAAREKEALAKERAGLAVQ 647
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEelgfesveeleERLKELEpfyneylELKDAEKELEREEKELKKLEEELDKAFEELAET 638

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622834693  648 LAAAEREGRTLS--------EEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEA 695
Cdd:PRK03918   639 EKRLEELRKELEelekkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 778-1190 6.52e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.81  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  778 QLQSQLQREQEELLARLEAEKEELSEEIATLQQERDE-GLLLAE-SEKQQALSLKESEKTALSEKLMGTRHSLATISLEM 855
Cdd:pfam10174  338 QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEkSTLAGEiRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQL 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  856 ERQKRDAQSRQEQDRSTVNALTSelrdlraqLEEAVAAHAQEVRRLQEQAQDLGKQRdscLREAEELRTQLRLLEDARDG 935
Cdd:pfam10174  418 AGLKERVKSLQTDSSNTDTALTT--------LEEALSEKERIIERLKEQREREDRER---LEELESLKKENKDLKEKVSA 486

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  936 LRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKlANEDKEQKLALLEe 1015
Cdd:pfam10174  487 LQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVR-TNPEINDRIRLLE- 564

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1016 artavgkeagelrtglQEVERSRLEARRELQELRRQMKML-DSENTRLGRElaelqgrlalgeraEKESRRETLGLRQrl 1094
Cdd:pfam10174  565 ----------------QEVARYKEESGKAQAEVERLLGILrEVENEKNDKD--------------KKIAELESLTLRQ-- 612

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1095 lkgeasleVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGR 1174
Cdd:pfam10174  613 --------MKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQS 684

                          410
                   ....*....|....*.
gi 1622834693 1175 AQGLEAELARVEAQRR 1190
Cdd:pfam10174  685 LAEKDGHLTNLRAERR 700
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 380-1048 7.29e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 7.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  380 QQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLE----------QLEGKRSVLAKELVEVR 449
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETElcaeaeemraRLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  450 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 529
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  530 AALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGR 609
Cdd:pfam01576  162 SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  610 EQELEQA----------RRAAQRQMEALERAARE-KEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFE 678
Cdd:pfam01576  242 EEELQAAlarleeetaqKNNALKKIRELEAQISElQEDLESERA----ARNKAEKQRRDLGEELEALKTELEDTLDTTAA 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  679 VQrqlaQLEARREhleaegQALLLAKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAEReAQASLREQRAAHEEDL 758
Cdd:pfam01576  318 QQ----ELRSKRE------QEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKR-NKANLEKAKQALESEN 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  759 QRLQREK---EAAWRELEAERAQLQSQLQreqeELLARLEAEKEELSEEiatlqqerdeglllaeSEKQQALSLKESEKT 835
Cdd:pfam01576  387 AELQAELrtlQQAKQDSEHKRKKLEGQLQ----ELQARLSESERQRAEL----------------AEKLSKLQSELESVS 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  836 ALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL---RAQLEEAVAAHAQEVRRLQEQAQDLGKQR 912
Cdd:pfam01576  447 SLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLedeRNSLQEQLEEEEEAKRNVERQLSTLQAQL 526

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  913 DSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKK- 991
Cdd:pfam01576  527 SDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKf 606

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622834693  992 ----AESERISLKLANE-DKEQKLALLEEART-AVGKEAGELRTGLQEVERSRLEARRELQEL 1048
Cdd:pfam01576  607 dqmlAEEKAISARYAEErDRAEAEAREKETRAlSLARALEEALEAKEELERTNKQLRAEMEDL 669
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
879-1212 7.43e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 7.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  879 ELRDLRAQLEEAVAAHAQEVRRLQEQAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQR 958
Cdd:COG4372     14 SLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  959 QEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSR 1038
Cdd:COG4372     94 AELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1039 LEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQ 1118
Cdd:COG4372    174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1119 EGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGG 1198
Cdd:COG4372    254 EVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333

                          330
                   ....*....|....
gi 1622834693 1199 LRSALRRGLGLGRA 1212
Cdd:COG4372    334 ILLAELADLLQLLL 347
PRK11281 PRK11281
mechanosensitive channel MscK;
494-767 8.58e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 8.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  494 EASLQDSLSKLSALNESLAQDKL---DLN---RLVAQLEEEKAALQGRQRQAEQ-EATVAREEQERLEELRLEQEVARQG 566
Cdd:PRK11281    38 EADVQAQLDALNKQKLLEAEDKLvqqDLEqtlALLDKIDRQKEETEQLKQQLAQaPAKLRQAQAELEALKDDNDEETRET 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  567 LEgSLRVAEqaqevLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRA---AQRQMEALERaarekealakerag 643
Cdd:PRK11281   118 LS-TLSLRQ-----LESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAAlyaNSQRLQQIRN-------------- 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  644 lavQLAAAEREGRTLSEEA-TRLRLEKEALEgslfevqrqlAQLEARREHLEAEG--QALLLAK-ETLTGELAGLRQQII 719
Cdd:PRK11281   178 ---LLKGGKVGGKALRPSQrVLLQAEQALLN----------AQNDLQRKSLEGNTqlQDLLQKQrDYLTARIQRLEHQLQ 244

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1622834693  720 AIQEkasldkELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEA 767
Cdd:PRK11281   245 LLQE------AINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEI 286
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1275-1763 8.86e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 8.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1275 QEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSvdgRLSGVQAEMALQEESVRrs 1354
Cdd:pfam12128  290 QLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE---QLPSWQSELENLEERLK-- 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1355 ererrATLDQIATLERSLQATESelRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQ-RRSLEGELQRSRL 1433
Cdd:pfam12128  365 -----ALTGKHQDVTAKYNRRRS--KIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1434 GLSDREAQAQALQDRVDSLQrqvADSEVKAgTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNL 1513
Cdd:pfam12128  438 EEYRLKSRLGELKLRLNQAT---ATPELLL-QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASR 513

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1514 HLQKALTACEHdrqvLQERLDAARQAL-----SEARKQSSSLGEQVQT-------LRGEVAD-------------LELQQ 1568
Cdd:pfam12128  514 RLEERQSALDE----LELQLFPQAGTLlhflrKEAPDWEQSIGKVISPellhrtdLDPEVWDgsvggelnlygvkLDLKR 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1569 VEAEGQLQQLREVLRQRQEGEAAalhmvqkLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKV 1648
Cdd:pfam12128  590 IDVPEWAASEEELRERLDKAEEA-------LQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEK 662

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1649 EREKLRSHEDTVRlsaekgrldrtltgaelELAEAQRQIQQLEAQVVVLEQSHSPAQLEVD-----AQQQQHLELQQEVE 1723
Cdd:pfam12128  663 QSEKDKKNKALAE-----------------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKeqkreARTEKQAYWQVVEG 725

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 1622834693 1724 RLRSAQVQTERTLEARERAHRQRVRGLEEQVCRPPRKAGP 1763
Cdd:pfam12128  726 ALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGV 765
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1535-1708 1.03e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.08  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1535 AARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVL---RQRQEGEAAALHMVQKLQDERRLLQERLG 1611
Cdd:COG2433    403 HEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELseaRSEERREIRKDREISRLDREIERLERELE 482

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1612 SLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEaqrQIQQLE 1691
Cdd:COG2433    483 EERERIEELKRKLERLKELWKLEHSGELVPVKVVEKFTKEAIRRLEEEYGLKEGDVVYLRDASGAGRSTAE---LLAEAG 559

                          170
                   ....*....|....*..
gi 1622834693 1692 AQVVVLEQSHSPAQLEV 1708
Cdd:COG2433    560 PRAVIVPGELSEAADEV 576
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 451-794 1.05e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.27  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  451 ALSRATLQRDMLQAE------KAEVAEALTKAEAGRVELELSMTKLRAEEASLqDSLSKLSA------LNESLAQDKLDL 518
Cdd:PRK10929    22 APDEKQITQELEQAKaaktpaQAEIVEALQSALNWLEERKGSLERAKQYQQVI-DNFPKLSAelrqqlNNERDEPRSVPP 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  519 NRLVAQLEEE----KAALQGRQRQAEQEATVAREEQERLEELRLEQEVAR----------QGLEGSLRVAEQAQEVLEQQ 584
Cdd:PRK10929   101 NMSTDALEQEilqvSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARrqlneierrlQTLGTPNTPLAQAQLTALQA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  585 LPTLRheRSRLQE-QLAQLS---RQ-LSGREQELEQARRA--------------AQRQMEAlERAAREKEALAKERAGLA 645
Cdd:PRK10929   181 ESAAL--KALVDElELAQLSannRQeLARLRSELAKKRSQqldaylqalrnqlnSQRQREA-ERALESTELLAEQSGDLP 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  646 VQLAAAEREGRTLSEEatrlrLEKEALEGSLF-EVQRQLAQ--LEARREHLEAEGQALLLAKETLTGElaGLRQQIIAIQ 722
Cdd:PRK10929   258 KSIVAQFKINRELSQA-----LNQQAQRMDLIaSQQRQAASqtLQVRQALNTLREQSQWLGVSNALGE--ALRAQVARLP 330

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693  723 EKAsldkelmaqKLVQAEREaQASLREQRAAHEEDLQRLQRE---KEAAWRELEAERAQLQSQLQREQEELLARL 794
Cdd:PRK10929   331 EMP---------KPQQLDTE-MAQLRVQRLRYEDLLNKQPQLrqiRQADGQPLTAEQNRILDAQLRTQRELLNSL 395
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1280-1707 1.08e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1280 ELRSAQRERDDLRTQTSALSHQLAEMEAERdHATLRARQLQKAVAES------------EEARRSVDGRLSGVQAEMALQ 1347
Cdd:pfam15921  357 ELTEARTERDQFSQESGNLDDQLQKLLADL-HKREKELSLEKEQNKRlwdrdtgnsitiDHLRRELDDRNMEVQRLEALL 435

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1348 EESVRRSErerratldqiATLERSLQATESElRASQEKISKMKAnetKLEGDKRRLKEVLDASESRTVKLELQRRS---L 1424
Cdd:pfam15921  436 KAMKSECQ----------GQMERQMAAIQGK-NESLEKVSSLTA---QLESTKEMLRKVVEELTAKKMTLESSERTvsdL 501

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1425 EGELQRSRLGLSDREAQAQALQDRVD-SLQ--RQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQS 1501
Cdd:pfam15921  502 TASLQEKERAIEATNAEITKLRSRVDlKLQelQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQH 581

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1502 SASLNSTQDKNLHLQKALtaceHDRqvlqerldaaRQALSEARKQSSSLGEQVQTLRGEVADLELQQVE-AEGQLQQLRE 1580
Cdd:pfam15921  582 GRTAGAMQVEKAQLEKEI----NDR----------RLELQEFKILKDKKDAKIRELEARVSDLELEKVKlVNAGSERLRA 647

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1581 VLRQRQEGEaaalhmvqKLQDERRLLQERLGSLQRalaQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV 1660
Cdd:pfam15921  648 VKDIKQERD--------QLLNEVKTSRNELNSLSE---DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLK 716

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1622834693 1661 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLE 1707
Cdd:pfam15921  717 SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKE 763
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 972-1226 1.10e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  972 AKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRrq 1051
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK-- 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1052 mkmldsentrlgrelAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEfRTRERRLLG 1131
Cdd:COG4942    104 ---------------EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD-LAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1132 SLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQLGGLRSALRR---GLG 1208
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAErtpAAG 247

                          250
                   ....*....|....*...
gi 1622834693 1209 LGRAPSPAPRPVPGSPAR 1226
Cdd:COG4942    248 FAALKGKLPWPVSGRVVR 265
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1274-1707 1.15e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1274 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQaEMALQEESVRR 1353
Cdd:PRK03918   219 LREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIK 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1354 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLEL--QRRSLEGELQRS 1431
Cdd:PRK03918   298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeEAKAKKEELERL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1432 RLGLSDR-----EAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEA-----LAQS 1501
Cdd:PRK03918   378 KKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhrkelLEEY 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1502 SASLNStqdknlhLQKALTACEHDRQVLQERLDAARQALSEARKQSS--SLGEQVQTLRGEVADLELQQVEAEGQ----L 1575
Cdd:PRK03918   458 TAELKR-------IEKELKEIEEKERKLRKELRELEKVLKKESELIKlkELAEQLKELEEKLKKYNLEELEKKAEeyekL 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1576 QQLREVLRQRQEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRValrRTLDKVEREKLRS 1655
Cdd:PRK03918   531 KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL---KELEPFYNEYLEL 607

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693 1656 HEDTVRLSAEKGRLDR---TLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLE 1707
Cdd:PRK03918   608 KDAEKELEREEKELKKleeELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE 662
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
304-996 1.16e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  304 RYEASQDLLGTLRKQLsdsESERRALEEQLQRlrdktdgamqaQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAE 383
Cdd:PRK03918   159 DYENAYKNLGEVIKEI---KRRIERLEKFIKR-----------TENIEELIKEKEKELEEVLREINEISSELPELREELE 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  384 ELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVrRELErshRQLEQLEGKRSVLAKELVEVREALSRATlqrdmlq 463
Cdd:PRK03918   225 KLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKI-RELE---ERIEELKKEIEELEEKVKELKELKEKAE------- 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  464 aEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQdkldLNRLVAQLEEEKAALQGRQRQAEqea 543
Cdd:PRK03918   294 -EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE----LKKKLKELEKRLEELEERHELYE--- 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  544 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSgreqELEQARRAAQRQ 623
Cdd:PRK03918   366 EAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE----ELKKAKGKCPVC 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  624 MEALERAAReKEALAKERAglavQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLA 703
Cdd:PRK03918   442 GRELTEEHR-KELLEEYTA----ELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYN 516

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  704 KETLtgelaglrqqiiaiqEKASLDKELMAQKLvqAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQL 783
Cdd:PRK03918   517 LEEL---------------EKKAEEYEKLKEKL--IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL 579

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  784 QREQEELLARLeaekeelSEEIATLQQERDEGLLL--AESEKQQALSLKESEKTALS---EKLMGTRHSLATISLEMER- 857
Cdd:PRK03918   580 EELGFESVEEL-------EERLKELEPFYNEYLELkdAEKELEREEKELKKLEEELDkafEELAETEKRLEELRKELEEl 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  858 QKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAvaahaqeVRRLQEQAQDLGKQRDScLREAEELRTQLRLLEDARDGLr 937
Cdd:PRK03918   653 EKKYSEEEYEELREEYLELSRELAGLRAELEEL-------EKRREEIKKTLEKLKEE-LEEREKAKKELEKLEKALERV- 723

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834693  938 RELLEAQRKLRESQEGREVQRQE--AGELRRSLGEGAKEREALRRSNEELRAAVKKAESER 996
Cdd:PRK03918   724 EELREKVKKYKALLKERALSKVGeiASEIFEELTEGKYSGVRVKAEENKVKLFVVYQGKER 784
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
841-1123 1.17e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  841 LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLE---EAVAAHAQEVRRLQEQAQDLGKQRDSCLR 917
Cdd:COG4372     15 LFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEqleEELEQARSELEQLEEELEELNEQLQAAQA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  918 EAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERI 997
Cdd:COG4372     95 ELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQ 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  998 SLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE 1077
Cdd:COG4372    175 ALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEE 254

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1622834693 1078 RAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFR 1123
Cdd:COG4372    255 VILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLAL 300
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
608-787 1.20e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 43.32  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  608 GREQeLEQARRAAQRQMEALERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATRLRLEKEAlegslFEVQRQLAQLE 687
Cdd:COG2268    190 GRRK-IAEIIRDARIAEAEAERETEIAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAE-----ERREAETARAE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  688 ARREHLEAEGQALLLAKETLTgelAGLRQQIIAIQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEA 767
Cdd:COG2268    264 AEAAYEIAEANAEREVQRQLE---IAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAKGLAEA 340

                          170       180
                   ....*....|....*....|
gi 1622834693  768 AWRELEAERAQLQSQLQREQ 787
Cdd:COG2268    341 EGKRALAEAWNKLGDAAILL 360
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1274-1507 1.31e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1274 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRr 1353
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA- 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1354 sererratlDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRL 1433
Cdd:COG4942    108 ---------ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834693 1434 GLSDREAQAQALQDRVDSLQRQVADsevkagtLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNS 1507
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLAR-------LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PTZ00121 PTZ00121
MAEBL; Provisional
 290-504 1.37e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  290 ALHKRQLQVQDMRGRYEASQDLLGTLRKQlsDSESERRALEEQL--QRLRDKTDGAMQAQEDAQREVQRLRSANELLSRE 367
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKLYEEEKKM--KAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE 1656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  368 KSNLAHSLQVAQQQAEELRQErEKLQAAQEELRRQRDRLEEEQEDAvQDGARVRRELERSHRQLEQL---EGKRSVLAKE 444
Cdd:PTZ00121  1657 EENKIKAAEEAKKAEEDKKKA-EEAKKAEEDEKKAAEALKKEAEEA-KKAEELKKKEAEEKKKAEELkkaEEENKIKAEE 1734

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  445 LVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKL 504
Cdd:PTZ00121  1735 AKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1030-1738 1.52e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 1.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1030 GLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQG-----------RLALGERAEKESRRETLGLRQRLLKGE 1098
Cdd:TIGR02169  164 GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaeryqalLKEKREYEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1099 ASLEVMRQELQVAQRKLQEQEGEFRTRERRLLgslEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGL 1178
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLE---ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1179 EAELARVEAQRRAAEAQLGGLRSALRRglglgrapspaprpvpgspardaaaggsgdglsspSNLECSPGSQPPSPGPAT 1258
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEE-----------------------------------ERKRRDKLTEEYAELKEE 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1259 SpappdldpETVRGALQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEArrsvdgrls 1338
Cdd:TIGR02169  366 L--------EDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA--------- 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1339 gvqaemalqeesvrrsereRRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLE 1418
Cdd:TIGR02169  429 -------------------IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1419 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAK--VEESEGALRDKVRGLTE 1496
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvVVEDDAVAKEAIELLKR 569

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1497 ALA-----------QSSASLNSTQDKNLHLQKALTACEHDRQ------------VLQERLDAARQALSEAR--------- 1544
Cdd:TIGR02169  570 RKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEFDPKyepafkyvfgdtLVVEDIEAARRLMGKYRmvtlegelf 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1545 -KQSSSLGEQVQTLRGEVADL----ELQQVEAE-GQLQQLREVLRQRQ-EGEAAALHMVQKLQDERRLLQERLGSLQRAL 1617
Cdd:TIGR02169  650 eKSGAMTGGSRAPRGGILFSRsepaELQRLRERlEGLKRELSSLQSELrRIENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1618 AQLEAEKREVERSALRL---EKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAEL-----ELAEAQRQIQQ 1689
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLsslEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIpeiqaELSKLEEEVSR 809

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 1622834693 1690 LEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEA 1738
Cdd:TIGR02169  810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858
PRK09039 PRK09039
peptidoglycan -binding protein;
1048-1195 1.80e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1048 LRRQMKMLDSENTRLGRELAELQGRLALgERAEKESRRETLGlrqRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRER 1127
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSL-ERQGNQDLQDSVA---NLRASLSAAEAERSRLQALLAELAGAGAAAEGRAG 119

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622834693 1128 RLLGSLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELARVEAQRRAAEAQ 1195
Cdd:PRK09039   120 ELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLGRRLNVALAQ 187
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1535-1753 2.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1535 AARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEgeaaalhMVQKLQDERRLLQERLGSLQ 1614
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-------RIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1615 RALAQLEAEkreversalrLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQ- 1693
Cdd:COG4942     90 KEIAELRAE----------LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADl 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693 1694 --VVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHRQRVRGLEEQ 1753
Cdd:COG4942    160 aeLAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
328-637 2.39e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  328 ALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE 407
Cdd:COG4372     28 ALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQ 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  408 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 487
Cdd:COG4372    108 EEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDE 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  488 TKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGL 567
Cdd:COG4372    188 LLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  568 EGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEAL 637
Cdd:COG4372    268 LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLA 337
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1529-1693 2.41e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1529 LQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQEGEAAALHMVQKLQDERRLLQE 1608
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1609 RLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLtgAELELAEAQRQIQ 1688
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL--QALSEAEAEQALD 186


                   ....*
gi 1622834693 1689 QLEAQ 1693
Cdd:COG4372    187 ELLKE 191
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 612-993 2.65e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 2.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  612 ELEQARRAAQRQMEA-LERAAREKEALAKERAGLAVQLAAAEREGRTLSEEATrlrlekealegslfEVQRQLAQLEARR 690
Cdd:pfam07888   45 ELLQAQEAANRQREKeKERYKRDREQWERQRRELESRVAELKEELRQSREKHE--------------ELEEKYKELSASS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  691 EHLEAEGQALLLAKETLTGELAGLRQQIIAIQEKAsLDKELMAQKLVQAEREAQASLREQRAAHEeDLQRLQREKEAAWR 770
Cdd:pfam07888  111 EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRV-LERETELERMKERAKKAGAQRKEEEAERK-QLQAKLQQTEEELR 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  771 ELEAERAQLQSQL-QREQEELLARLEAEKEELSEEIATLQQERDEGLLLAESEKQQALSLKESEKTALSEKLMgtrhsla 849
Cdd:pfam07888  189 SLSKEFQELRNSLaQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELS------- 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  850 tislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQAQdlgKQRDSCLREAEELRTQLRLL 929
Cdd:pfam07888  262 ----SMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAE---ADKDRIEKLSAELQRLEERL 334

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834693  930 EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAE 993
Cdd:pfam07888  335 QEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
571-779 2.69e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 42.37  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  571 LRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSR-QLS-GREQELEQARR---AAQRQMEALERAArekEALAKERAGLA 645
Cdd:COG0497    167 WRALKKELEELRADEAERARELDLLRFQLEELEAaALQpGEEEELEEERRrlsNAEKLREALQEAL---EALSGGEGGAL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  646 VQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALllakETLTGELAGLRQ--------- 716
Cdd:COG0497    244 DLLGQALRALERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEFDPERL----EEVEERLALLRRlarkygvtv 319

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834693  717 -QIIAIQEKasldkelMAQKLVQAEreaqaslreqraAHEEDLQRLQREKEAAWRELEAERAQL 779
Cdd:COG0497    320 eELLAYAEE-------LRAELAELE------------NSDERLEELEAELAEAEAELLEAAEKL 364
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 729-1069 2.70e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  729 KELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEEL------LARLEAEKEELS 802
Cdd:pfam07888   28 RAELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELrqsrekHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  803 EEIATLQQERDeGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER---QKRDAQSRQEQDRSTVNALTSE 879
Cdd:pfam07888  108 ASSEELSEEKD-ALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKagaQRKEEEAERKQLQAKLQQTEEE 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  880 LRDLRAQLEEAVAAHAQ---EVRRLQE----------QAQDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 946
Cdd:pfam07888  187 LRSLSKEFQELRNSLAQrdtQVLQLQDtittltqkltTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQ 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  947 LRESQEGREVQRQEAGELRRSLGE-GAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAG 1025
Cdd:pfam07888  267 RDRTQAELHQARLQAAQLTLQLADaSLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEV 346

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1622834693 1026 ELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAEL 1069
Cdd:pfam07888  347 ELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQEL 390
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 294-514 2.87e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.73  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  294 RQLQVQDMRGRyEASqDLLGTLRKQLSDSeseRRALEEQLQRLRDKTDG----------AMQAQEDAQR----------- 352
Cdd:PRK10929   123 RQAQQEQDRAR-EIS-DSLSQLPQQQTEA---RRQLNEIERRLQTLGTPntplaqaqltALQAESAALKalvdelelaql 197

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  353 ------EVQRLRSanELLSREKSNLAHSLQVAQQQAEELRQereklQAAQEELRRQRdRLEEEQED---AVQDGARVRRE 423
Cdd:PRK10929   198 sannrqELARLRS--ELAKKRSQQLDAYLQALRNQLNSQRQ-----REAERALESTE-LLAEQSGDlpkSIVAQFKINRE 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  424 LERSHRQ----LEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAeVAEALtKAEAGRV-------ELELSMTKLRA 492
Cdd:PRK10929   270 LSQALNQqaqrMDLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNA-LGEAL-RAQVARLpempkpqQLDTEMAQLRV 347

                          250       260
                   ....*....|....*....|..
gi 1622834693  493 EEASLQDSLSKLSALNESLAQD 514
Cdd:PRK10929   348 QRLRYEDLLNKQPQLRQIRQAD 369
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1274-1744 3.47e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1274 LQEFLQELRSAQRERDDLRTQTSALSHQLAEMEAErdhaTLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRR 1353
Cdd:TIGR04523  175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKK----IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1354 SERERRATLDQIATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELqrRSLEGELQRSRL 1433
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSEL--KNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1434 GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTealaqssaslNSTQDKNL 1513
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE----------SQINDLES 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1514 HLQKAltacEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLrEVLRQRQEGEAAAL 1593
Cdd:TIGR04523  399 KIQNQ----EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNL-DNTRESLETQLKVL 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1594 HM-VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRT 1672
Cdd:TIGR04523  474 SRsINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFE 553

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622834693 1673 LTGAELE--LAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQHLELQQEVERLRSAQVQTERTLEARERAHR 1744
Cdd:TIGR04523  554 LKKENLEkeIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENE 627
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 400-695 3.82e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  400 RRQRDRLEE-EQEDAVQDGARVRRELERsHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMlqaEKAEVAEALTKAEA 478
Cdd:pfam17380  287 RQQQEKFEKmEQERLRQEKEEKAREVER-RRKLEEAEKARQAEMDRQAAIYAEQERMAMERER---ELERIRQEERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  479 GRV---ELELSMTKLRAEEASLQDSLSKlsalNESLAQDkLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEE 555
Cdd:pfam17380  363 ERIrqeEIAMEISRMRELERLQMERQQK----NERVRQE-LEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREV 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  556 LRLEQEVARQglegSLRVAEQAQEvLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKE 635
Cdd:pfam17380  438 RRLEEERARE----MERVRLEEQE-RQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622834693  636 ALAK--ERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEgslfEVQRQLAQLEARREHLEA 695
Cdd:pfam17380  513 RKRKllEKEMEERQKAIYEEERRREAEEERRKQQEMEERR----RIQEQMRKATEERSRLEA 570
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
145-682 4.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 4.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  145 AQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAvl 224
Cdd:COG4913    240 AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEAR-- 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  225 sdsesgvqlsgsertADASDGSLRGLSGQrtpsppRRSSPGRgrsprrgpspacsdssTLALIHSALHKRQLQVQDMRGR 304
Cdd:COG4913    318 ---------------LDALREELDELEAQ------IRGNGGD----------------RLEQLEREIERLERELEERERR 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  305 YEASQDLLGTLRKQLSDSESE-----------RRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAH 373
Cdd:COG4913    361 RARLEALLAALGLPLPASAEEfaalraeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  374 SLQVAQQQ-AEELRQEREKLQ-----------------AAQEELRRQRDRL--EEEQEDAV-------QDGARVRRELER 426
Cdd:COG4913    441 RLLALRDAlAEALGLDEAELPfvgelievrpeeerwrgAIERVLGGFALTLlvPPEHYAAAlrwvnrlHLRGRLVYERVR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  427 SHRQLEQLE--GKRSVLAKelVEVREALSRATLQR---------------DMLQAEKAEVAEALTKAEAGRVELELSmTK 489
Cdd:COG4913    521 TGLPDPERPrlDPDSLAGK--LDFKPHPFRAWLEAelgrrfdyvcvdspeELRRHPRAITRAGQVKGNGTRHEKDDR-RR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  490 LRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLE- 568
Cdd:COG4913    598 IRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAEl 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  569 GSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKE----ALAKERAGL 644
Cdd:COG4913    678 ERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARlelrALLEERFAA 757

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1622834693  645 AVQLAAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQ 682
Cdd:COG4913    758 ALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 284-690 4.34e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.02  E-value: 4.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  284 LALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSES---ERRALE---EQLQRLRDKTDGAMQAQE----DAQRE 353
Cdd:pfam05483  379 LKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKlldEKKQFEkiaEELKGKEQELIFLLQAREkeihDLEIQ 458

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  354 VQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQ 433
Cdd:pfam05483  459 LTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIEN 538

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  434 LEGKRSVLAKELVEVREALSRatlQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 513
Cdd:pfam05483  539 LEEKEMNLRDELESVREEFIQ---KGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQ 615

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  514 DKLDLNRLVAQLEEEKAALQGRQRQAEQE-ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHER 592
Cdd:pfam05483  616 ENKALKKKGSAENKQLNAYEIKVNKLELElASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID 695

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  593 SRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALERAAREKEALakeRAGLAVQLAAAEREGRTLSEEatrLRLEKEAL 672
Cdd:pfam05483  696 KRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSA---KAALEIELSNIKAELLSLKKQ---LEIEKEEK 769

                          410
                   ....*....|....*...
gi 1622834693  673 EGSLFEVQRQLAQLEARR 690
Cdd:pfam05483  770 EKLKMEAKENTAILKDKK 787
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 611-951 4.38e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 4.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  611 QELEQARRAAQRQMEALERAAREKEAL---AKERAGLAVQLAAAEREGRTLSEEATRLRLEKEALEGS--LFEVQRQLA- 684
Cdd:PRK10929    48 EALQSALNWLEERKGSLERAKQYQQVIdnfPKLSAELRQQLNNERDEPRSVPPNMSTDALEQEILQVSsqLLEKSRQAQq 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  685 ------------------QLEARREHLEAEGQALLLAKETLTGELAGLrqqiiaiqekASLDKELMAQKLVQAERE-AQA 745
Cdd:PRK10929   128 eqdrareisdslsqlpqqQTEARRQLNEIERRLQTLGTPNTPLAQAQL----------TALQAESAALKALVDELElAQL 197

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  746 SlreqrAAHEEDLQRL-----QREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEEL----SEEIATLQQERDegL 816
Cdd:PRK10929   198 S-----ANNRQELARLrselaKKRSQQLDAYLQALRNQLNSQRQREAERALESTELLAEQSgdlpKSIVAQFKINRE--L 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  817 LLAESEKQQALSLKESEKTALSEKLMGTRHSLATIslemerqkrdaqSRQEQDRSTVNALTSELRDLRAQLEeavaahaq 896
Cdd:PRK10929   271 SQALNQQAQRMDLIASQQRQAASQTLQVRQALNTL------------REQSQWLGVSNALGEALRAQVARLP-------- 330

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693  897 EVRRLQEQAQDLGKQRDSCLReAEELRTQLRLLEDARDGLRRELLEAQRKLRESQ 951
Cdd:PRK10929   331 EMPKPQQLDTEMAQLRVQRLR-YEDLLNKQPQLRQIRQADGQPLTAEQNRILDAQ 384
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 294-961 4.74e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 4.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  294 RQLQVQDMRGRYEASQDLLGTLRKQLSDSEserRALEEQLQRlrdktdgAMQAQEDAQR--EVQRLRSANELLSREKSNL 371
Cdd:COG3096    373 AAEQLAEAEARLEAAEEEVDSLKSQLADYQ---QALDVQQTR-------AIQYQQAVQAleKARALCGLPDLTPENAEDY 442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  372 AHSLQVAQQQA-EELRQEREKLQAAQEElRRQRDRLEEEQEDAVQDGAR-----VRRELERSHRQLEQLEGKRSVLAKEL 445
Cdd:COG3096    443 LAAFRAKEQQAtEEVLELEQKLSVADAA-RRQFEKAYELVCKIAGEVERsqawqTARELLRRYRSQQALAQRLQQLRAQL 521

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  446 VEVREALSRatlqrdmlQAEKAEVAEALTKAEAGRVELELSMTKLRAEeaslqdslskLSALNESLAQDKLDLNRLVAQL 525
Cdd:COG3096    522 AELEQRLRQ--------QQNAERLLEEFCQRIGQQLDAAEELEELLAE----------LEAQLEELEEQAAEAVEQRSEL 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  526 EEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVArqgLEGSLRVAEQAQEVLEQQLPT------LRHERSRLQEQL 599
Cdd:COG3096    584 RQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEA---LADSQEVTAAMQQLLEREREAtverdeLAARKQALESQI 660

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  600 AQLS---------------------------------------------------------RQLSGRE------------ 610
Cdd:COG3096    661 ERLSqpggaedprllalaerlggvllseiyddvtledapyfsalygparhaivvpdlsavkEQLAGLEdcpedlyliegd 740

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  611 -----------QELEQAR--RAAQRQME--------ALERAAREK--EALAKERAGLAVQLAAAEREGRTLSeeatRLRL 667
Cdd:COG3096    741 pdsfddsvfdaEELEDAVvvKLSDRQWRysrfpevpLFGRAAREKrlEELRAERDELAEQYAKASFDVQKLQ----RLHQ 816

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  668 EKEALEGSLFEV------QRQLAQLEARREHLEAEgqalllaKETLTGELAGLRQQIIAIQEKASLDKELMAQKLVQAER 741
Cdd:COG3096    817 AFSQFVGGHLAVafapdpEAELAALRQRRSELERE-------LAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADE 889

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  742 EAQA---SLREQRAAHEEDLQRLQREKEAAwRELEAERAQLQS------QLQREQEELLARLeaekEELSEEIATLQQER 812
Cdd:COG3096    890 TLADrleELREELDAAQEAQAFIQQHGKAL-AQLEPLVAVLQSdpeqfeQLQADYLQAKEQQ----RRLKQQIFALSEVV 964

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  813 DEGLLLAESEKQQALslkeSEKTALSEKLmgtRHSLAtislEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQLEeava 892
Cdd:COG3096    965 QRRPHFSYEDAVGLL----GENSDLNEKL---RARLE----QAEEARREAREQLRQAQAQYSQYNQVLASLKSSRD---- 1029

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  893 AHAQEVRRLQEQAQDLGKQRDSclrEAEE---------------LRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQ 957
Cdd:COG3096   1030 AKQQTLQELEQELEELGVQADA---EAEErarirrdelheelsqNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106


                   ....
gi 1622834693  958 RQEA 961
Cdd:COG3096   1107 REQV 1110
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 944-1196 4.75e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.80  E-value: 4.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  944 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAESERISLKLANEDKEQKLALLEEARTAVGKE 1023
Cdd:pfam07888   37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1024 AGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRelaelQGRLALGERAEKESRREtlGLRQRLLKGEASLEV 1103
Cdd:pfam07888  117 KDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKE-----RAKKAGAQRKEEEAERK--QLQAKLQQTEEELRS 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1104 MRQELQVAQRKLQEQEGEFRTrerrllgsLEEARGTEKQQLDHARGLELKLEATRAEAAELGLRLSAAEGRAQGLEAELA 1183
Cdd:pfam07888  190 LSKEFQELRNSLAQRDTQVLQ--------LQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELS 261

                          250
                   ....*....|...
gi 1622834693 1184 RVEAQRRAAEAQL 1196
Cdd:pfam07888  262 SMAAQRDRTQAEL 274
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 734-831 4.75e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.99  E-value: 4.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  734 QKLVQAEREAQASLREQRAAHEEDLQRLQREKEaawrELEAERAQLQSQLQREQEEL--LARLEAEKEELSEEIATLQQE 811
Cdd:COG0542    418 RRLEQLEIEKEALKKEQDEASFERLAELRDELA----ELEEELEALKARWEAEKELIeeIQELKEELEQRYGKIPELEKE 493

                           90       100
                   ....*....|....*....|
gi 1622834693  812 RDEgllLAESEKQQALSLKE 831
Cdd:COG0542    494 LAE---LEEELAELAPLLRE 510
PRK09039 PRK09039
peptidoglycan -binding protein;
1471-1579 5.02e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.10  E-value: 5.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1471 ERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQDKNLHLQKALTACEHDRQVLQER-------LDAARQALSEA 1543
Cdd:PRK09039    56 DRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRagelaqeLDSEKQVSARA 135

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1622834693 1544 RKQSSSLGEQVQTLRGEVADLE--LQQVEAEGQLQQLR 1579
Cdd:PRK09039   136 LAQVELLNQQIAALRRQLAALEaaLDASEKRDRESQAK 173
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 593-835 5.07e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 5.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  593 SRLQE----QLAQLSRQLSGreQELEQARRAAQRQMEALE--RAAREKEALAKERAGlavqlaaaEREGRTLSEEATRLR 666
Cdd:PRK05771    23 EALHElgvvHIEDLKEELSN--ERLRKLRSLLTKLSEALDklRSYLPKLNPLREEKK--------KVSVKSLEELIKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  667 LEKEALEGSLFEVQRQLAQLEARREHLEAEGQAL------------LLAKETLTGELAGL--RQQIIAIQEKASLDKELM 732
Cdd:PRK05771    93 EELEKIEKEIKELEEEISELENEIKELEQEIERLepwgnfdldlslLLGFKYVSVFVGTVpeDKLEELKLESDVENVEYI 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  733 AQK------LVQAEREAQASLREQRAAHEEDLQRLQREKEAAwRELEAERAQLqSQLQREQEELLARLEAEKEELSEEIA 806
Cdd:PRK05771   173 STDkgyvyvVVVVLKELSDEVEEELKKLGFERLELEEEGTPS-ELIREIKEEL-EEIEKERESLLEELKELAKKYLEELL 250

                          250       260       270
                   ....*....|....*....|....*....|
gi 1622834693  807 TLqqerdEGLLLAESEKQQALS-LKESEKT 835
Cdd:PRK05771   251 AL-----YEYLEIELERAEALSkFLKTDKT 275
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
1523-1631 5.29e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 41.37  E-value: 5.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1523 EHDRQVLQERLDAARQALSEARKQSS--SLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQRQegeaaalHMVQKLQ 1600
Cdd:COG3524    183 EEEVERAEERLRDAREALLAFRNRNGilDPEATAEALLQLIATLEGQLAELEAELAALRSYLSPNS-------PQVRQLR 255

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1622834693 1601 DERRLLQERLGSLQRALAQLEAEKREVERSA 1631
Cdd:COG3524    256 RRIAALEKQIAAERARLTGASGGDSLASLLA 286
PTZ00121 PTZ00121
MAEBL; Provisional
 293-529 5.37e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 5.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  293 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRD-KTDGAMQAQ--EDAQREVQRLRSANELlSREKS 369
Cdd:PTZ00121  1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEeKKMKAEEAKkaEEAKIKAEELKKAEEE-KKKVE 1636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  370 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 449
Cdd:PTZ00121  1637 QLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  450 EA--LSRATLQRDMLQAE-KAEVAEALTKAEAGRVElELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLE 526
Cdd:PTZ00121  1717 KAeeLKKAEEENKIKAEEaKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRME 1795


                   ...
gi 1622834693  527 EEK 529
Cdd:PTZ00121  1796 VDK 1798
PRK01156 PRK01156
chromosome segregation protein; Provisional
 409-1022 5.37e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 5.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  409 EQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMT 488
Cdd:PRK01156   139 EMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLK 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  489 KLRAEEASLQDSLSKLSALNESLaQDKLDLNRLVAQLEEEKAALQGR-QRQAEQEATVAREEQERLEELRLEQEVARQGL 567
Cdd:PRK01156   219 EIERLSIEYNNAMDDYNNLKSAL-NELSSLEDMKNRYESEIKTAESDlSMELEKNNYYKELEERHMKIINDPVYKNRNYI 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  568 EGSLRVAEQAqEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQELEQARRAAQRQMEALE---------RAAREKEALA 638
Cdd:PRK01156   298 NDYFKYKNDI-ENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILElegyemdynSYLKSIESLK 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  639 KERAGLAVQLaaaEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREHLEAEGQALLLAKETLTGELAGLRQQ- 717
Cdd:PRK01156   377 KKIEEYSKNI---ERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQs 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  718 -------------IIAIQEKASLDKELMAQKLVQAEREAQAsLREQRAAHEEDLQRLQREK----EAAWRELEAERAQLQ 780
Cdd:PRK01156   454 vcpvcgttlgeekSNHIINHYNEKKSRLEEKIREIEIEVKD-IDEKIVDLKKRKEYLESEEinksINEYNKIESARADLE 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  781 SqlqreqeellarleaekeeLSEEIATLQQERDEglllAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 860
Cdd:PRK01156   533 D-------------------IKIKINELKDKHDK----YEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRS 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  861 DAQSRQEQD-RSTVNALTSELRDLRAQLEEAVAAHAQEVRRLQEQ---AQDLGKQRDSCLREAEELRTQLrlleDARDGL 936
Cdd:PRK01156   590 NEIKKQLNDlESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKyneIQENKILIEKLRGKIDNYKKQI----AEIDSI 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  937 RRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRAAVKKAEsERISLKlanEDKEQKLALLEEA 1016
Cdd:PRK01156   666 IPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN-ETLESM---KKIKKAIGDLKRL 741


                   ....*.
gi 1622834693 1017 RTAVGK 1022
Cdd:PRK01156   742 REAFDK 747
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1280-1648 5.53e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1280 ELRSAQRERDDLRTQTSALSHQLAEMEAERDHATLRARQLQKAVAESEEARRSVDGRLSGVQAEMALQEESVRRSERERR 1359
Cdd:pfam01576  216 ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRR 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1360 ATLDQIATLERSLQATESELRASQEKISKMKANETKL-----EGDKRRLKEVLDASESRTVKLELQRRSLEgELQRSRLG 1434
Cdd:pfam01576  296 DLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELkkaleEETRSHEAQLQEMRQKHTQALEELTEQLE-QAKRNKAN 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1435 LSDR----EAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTQD 1510
Cdd:pfam01576  375 LEKAkqalESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEG 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1511 KNLHLQKALTACEHDRQVLQErldaarqALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEgqlQQLREVLRQRQEGEA 1590
Cdd:pfam01576  455 KNIKLSKDVSSLESQLQDTQE-------LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEE---EAKRNVERQLSTLQA 524

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622834693 1591 AALHMVQKLQDER---RLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKV 1648
Cdd:pfam01576  525 QLSDMKKKLEEDAgtlEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDL 585
PRK09039 PRK09039
peptidoglycan -binding protein;
577-699 7.36e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.72  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  577 AQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGREQ-------ELEQAR---RAAQRQMEALERAAREKEALAKERAGLAV 646
Cdd:PRK09039    40 AQFFLSREISGKDSALDRLNSQIAELADLLSLERQgnqdlqdSVANLRaslSAAEAERSRLQALLAELAGAGAAAEGRAG 119

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622834693  647 QLAAAEREGRTLSEEATRlrlEKEALEGSLFEVQRQLAQLEARREHLEAEGQA 699
Cdd:PRK09039   120 ELAQELDSEKQVSARALA---QVELLNQQIAALRRQLAALEAALDASEKRDRE 169
COG5283 COG5283
Phage-related tail protein [Mobilome: prophages, transposons];
311-411 7.40e-03

Phage-related tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444094 [Multi-domain]  Cd Length: 747  Bit Score: 41.38  E-value: 7.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  311 LLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRSANELLSREKSNLAHSLQVA----QQQAEELR 386
Cdd:COG5283      8 VDKPFKSALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQAgidtRQLSAAQR 87

                           90       100
                   ....*....|....*....|....*
gi 1622834693  387 QEREKLQAAQEELRRQRDRLEEEQE 411
Cdd:COG5283     88 RLRSSLEQTNRQLERQQQRLARLGA 112
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 282-445 7.66e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 7.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  282 STLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDA--QREVQRLRS 359
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEALQK 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  360 ANELLSREKSNLAhslqvaqqqaEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRS 439
Cdd:COG1579     97 EIESLKRRISDLE----------DEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166


                   ....*.
gi 1622834693  440 VLAKEL 445
Cdd:COG1579    167 ELAAKI 172
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 40-574 8.26e-03

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 41.40  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693   40 AWRREEesfnayfsnehsrllLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRTEAA 119
Cdd:COG3321    867 PFQRED---------------AAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLA 931

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  120 LEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVERLQKQNLEKDQVNKDLTEKLEALESLRLQ 199
Cdd:COG3321    932 LVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALL 1011

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  200 EQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASDGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACS 279
Cdd:COG3321   1012 LAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALA 1091

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  280 DSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAQEDAQREVQRLRS 359
Cdd:COG3321   1092 AAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAA 1171

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  360 ANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRS 439
Cdd:COG3321   1172 ALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAA 1251

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  440 VLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 519
Cdd:COG3321   1252 AAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALA 1331

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693  520 RLVAQLEEEKAALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVA 574
Cdd:COG3321   1332 ALAAAVAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAALAAAVA 1386
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
299-543 8.26e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  299 QDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTdGAMQAQEDAQREVQRLRSANellsreksnlahslqva 378
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKN-GLVDLSEEAKLLLQQLSELE----------------- 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  379 qQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGArvrrelershrqLEQLEGKRSVLAKELVEVREALSRATLQ 458
Cdd:COG3206    226 -SQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV------------IQQLRAQLAELEAELAELSARYTPNHPD 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  459 RDMLQAEKAEVAEALTK-AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKA---ALQG 534
Cdd:COG3206    293 VIALRAQIAALRAQLQQeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARElyeSLLQ 372


                   ....*....
gi 1622834693  535 RQRQAEQEA 543
Cdd:COG3206    373 RLEEARLAE 381
PRK11281 PRK11281
mechanosensitive channel MscK;
375-546 8.67e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.05  E-value: 8.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  375 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDgarVRRELE-RSHRQLEQLEGKRSVlakELVEVREALS 453
Cdd:PRK11281    72 LDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEE---TRETLStLSLRQLESRLAQTLD---QLQNAQNDLA 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  454 RA-----TLQRDMLQAEKA---------EVAEALTKAEAGRVELELSM-TKLRAEEASL--QDSLSKLSALNESLAQD-- 514
Cdd:PRK11281   146 EYnsqlvSLQTQPERAQAAlyansqrlqQIRNLLKGGKVGGKALRPSQrVLLQAEQALLnaQNDLQRKSLEGNTQLQDll 225

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1622834693  515 --KLDLNRL-VAQLEEEKAALQG---RQRQAEQEATVA 546
Cdd:PRK11281   226 qkQRDYLTArIQRLEHQLQLLQEainSKRLTLSEKTVQ 263
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1515-1710 9.11e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 9.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1515 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQQVEAEGQLQQLREVLRQR--------- 1585
Cdd:COG3883     21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaralyrsgg 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693 1586 ----------QEGEAAALHMVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1655
Cdd:COG3883    101 svsyldvllgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622834693 1656 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDA 1710
Cdd:COG3883    181 EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK11637 PRK11637
AmiB activator; Provisional
 379-634 9.47e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 40.45  E-value: 9.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  379 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVRealSRATLQ 458
Cdd:PRK11637    46 RDQLKSIQQDIAAKEKSVRQQQQQRASLLAQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLE---QQQAAQ 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  459 RDMLqaeKAEVAEALTKAEAGRVELELSmtklRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKAALQgrQRQ 538
Cdd:PRK11637   123 ERLL---AAQLDAAFRQGEHTGLQLILS----GEESQRGERILAYFGYLNQARQETIAELKQTREELAAQKAELE--EKQ 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  539 AEQEATVAreeqeRLEELRLEQEVARQGLEGSLRVAEQAQEVLEQQLPTLRHERSRLQEQLAQLSRQLSGR-EQELEQAR 617
Cdd:PRK11637   194 SQQKTLLY-----EQQAQQQKLEQARNERKKTLTGLESSLQKDQQQLSELRANESRLRDSIARAEREAKARaEREAREAA 268

                          250
                   ....*....|....*..
gi 1622834693  618 RAAQRQMEALERAAREK 634
Cdd:PRK11637   269 RVRDKQKQAKRKGSTYK 285
PLN02316 PLN02316
synthase/transferase
 382-445 9.53e-03

synthase/transferase


Pssm-ID: 215180 [Multi-domain]  Cd Length: 1036  Bit Score: 41.01  E-value: 9.53e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622834693  382 AEELRQEREKLQAAQEELRRQRD---RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKEL 445
Cdd:PLN02316   251 LEEKRRELEKLAKEEAERERQAEeqrRREEEKAAMEADRAQAKAEVEKRREKLQNLLKKASRSADNV 317
PRK12704 PRK12704
phosphodiesterase; Provisional
 348-497 9.91e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.53  E-value: 9.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  348 EDAQREVQRLRSANELLSREKsnlAHSLQvaQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS 427
Cdd:PRK12704    45 EEAKKEAEAIKKEALLEAKEE---IHKLR--NEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKEL 119

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622834693  428 HRQLEQLEGKRSVLAKELVEVREALSRATlqrdmlqaekaevaeALTKAEAGRVELELSMTKLRAEEASL 497
Cdd:PRK12704   120 EQKQQELEKKEEELEELIEEQLQELERIS---------------GLTAEEAKEILLEKVEEEARHEAAVL 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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