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Conserved domains on  [gi|1622872052|ref|XP_028690880|]
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LOW QUALITY PROTEIN: coiled-coil domain-containing protein 180 [Macaca mulatta]

Protein Classification

coiled-coil domain-containing protein 180( domain architecture ID 12169837)

coiled-coil domain-containing protein 180

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4455 pfam14643
Domain of unknown function (DUF4455); This domain family is found in bacteria and eukaryotes, ...
325-793 0e+00

Domain of unknown function (DUF4455); This domain family is found in bacteria and eukaryotes, and is approximately 480 amino acids in length. There are two completely conserved residues (W and P) that may be functionally important.


:

Pssm-ID: 464231 [Multi-domain]  Cd Length: 469  Bit Score: 612.36  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  325 AEHKRRSYEGALASFEEEIAQVGKEMEALIVDTAGLFLKKLTESDEEMNRLFLKVENDTNLEDYTIQALLELWDKVARRF 404
Cdd:pfam14643    1 AESRRERHEKALASFEKELASLSNEVEPLIAEAGELLLQKLAESDEEINALFKKLEDDDALEDYTIQQLEELWDIVAQHS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  405 LLQKQEIKELDEALHSLEFSRVNKLKGVLKKYAEVIEKTSYLMRPDVYKLINKEAMVMNYALLGNRKALAQLFINLMEST 484
Cdd:pfam14643   81 LLRKSWIKELDETLEKLEKERADKLKSVLKKYVEILEDIAHLLPPDVYRLIDKEAMEINQALLENRRAYAKLFANLMEAE 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  485 LQQELDSRHRWQGLVDTWKDLKKEALLQSFSEFMASESIHTPQAVVKELEVMLKTQNVLQQRRLKHLCTICDLLPPNYSK 564
Cdd:pfam14643  161 LKQELSFRLRWQDRVDRWKALKTEHLIQEFKEFIASEEIQNPPERKKELEEMLKEQKKLQQKRLELLQKISDLLPPAYSK 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  565 TQLTEWHSSLNSMNKELDTYHVDCMMRIRLLYEKTWQECLMLVQNCKKQLLDWKAFTEEEAETLVNQFFFQTVGALQGKV 644
Cdd:pfam14643  241 SKVEEWWASLEALNEQLDQYHDQCMTKLRAEYEEVWQECLARVQKLKQELLDYKVCSEEEAEALVNEEFLPLVGKLQRDA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  645 EEDLELLDKSFETLADQTEWQSSNLFRYFQEAVQLWEAHQSKLLVQELELEKRMEQHQQKHSLESQVQEAHLDRLLDQLR 724
Cdd:pfam14643  321 EDELEKLDKFLEELAKQTEAQSEDLFKFFREAAQLWDVHQTELAKQELELEKKLEQCRQKHDQENQAKEAALDKKLDQLR 400
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622872052  725 QQSDKETLAFHLEKVKDYLKNMKSRYEYFHTLLTKEVMEYPAIILKELNSYSSNLSQYFFVREIFEQNL 793
Cdd:pfam14643  401 QASTEEKLKECLDKALKFLDDIEKEYEDFHDKLTAIVKEYPTMILEELESYSTSLSQYFEVREIFEQNL 469
DUF4456 pfam14644
Domain of unknown function (DUF4456); This domain family is found in bacteria and eukaryotes, ...
1514-1718 3.80e-70

Domain of unknown function (DUF4456); This domain family is found in bacteria and eukaryotes, and is approximately 210 amino acids in length. There is a single completely conserved residue E that may be functionally important.


:

Pssm-ID: 464232  Cd Length: 209  Bit Score: 234.49  E-value: 3.80e-70
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052 1514 LLAVAEEFYR-KEKRPVTRPDCMYDTFDQCAENIGKKILDYQSQANKYHNSCLIELRIQMRRFEELLPQVCWLVMENFKE 1592
Cdd:pfam14644    1 LLSVAEPYYAqKGARPITRPEQIPETFEQCAENIQQKLLSYQEQADEYHNSCLQELRNQVERLEELLPSVPELIFESLLK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052 1593 HHWKMFCTSVKEIRGQFEGQQKQLEKRKDKNAQKLHLNLGHPIHFQEMESLHLSEDKRQEELDSMIRMNREKLEECTRRN 1672
Cdd:pfam14644   81 RHLQKLERAMKNIAAEFSQKQKQLEQLKQQHEQQLRPTLGHPQNAQELEQLCDREEDRQKEHIELIQAHREALLEAVDKV 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1622872052 1673 GQVFITNLAAFTEKFLLQLDEVVTIDDVQVA---RMEPPKQKLSMLIRR 1718
Cdd:pfam14644  161 ASTFVERLASLTEFLLLLFDSLLTPDDLQPLpgdAIEPKRKNLKVLLRR 209
RBP_receptor super family cl20677
Retinol binding protein receptor; Proteins in this family function as retinol binding protein ...
42-149 1.68e-45

Retinol binding protein receptor; Proteins in this family function as retinol binding protein receptors.


The actual alignment was detected with superfamily member pfam14752:

Pssm-ID: 464298  Cd Length: 603  Bit Score: 175.14  E-value: 1.68e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052   42 KAFHNFNYFLFFYNVLLGLGACLSRLLISCLLGTWLIARIDRTIMQNGYEGADMGFSAWIGMLYVDHYHTNPVLVSFCHI 121
Cdd:pfam14752  459 RALHLFTYLLFFYNVLVGLLACIWRLLISALYNIVHLGRIDRSLLQRGVEALDPGYRTYIGMLKIEVSQSHPVMKAFCGL 538
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1622872052  122 LI------------ANHKEKKLQQTTKYWCLNQSAESLRI 149
Cdd:pfam14752  539 LLqapkpqgraaqkPSDAEEGIQLLQTKKDFNAKGSGPRA 578
 
Name Accession Description Interval E-value
DUF4455 pfam14643
Domain of unknown function (DUF4455); This domain family is found in bacteria and eukaryotes, ...
325-793 0e+00

Domain of unknown function (DUF4455); This domain family is found in bacteria and eukaryotes, and is approximately 480 amino acids in length. There are two completely conserved residues (W and P) that may be functionally important.


Pssm-ID: 464231 [Multi-domain]  Cd Length: 469  Bit Score: 612.36  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  325 AEHKRRSYEGALASFEEEIAQVGKEMEALIVDTAGLFLKKLTESDEEMNRLFLKVENDTNLEDYTIQALLELWDKVARRF 404
Cdd:pfam14643    1 AESRRERHEKALASFEKELASLSNEVEPLIAEAGELLLQKLAESDEEINALFKKLEDDDALEDYTIQQLEELWDIVAQHS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  405 LLQKQEIKELDEALHSLEFSRVNKLKGVLKKYAEVIEKTSYLMRPDVYKLINKEAMVMNYALLGNRKALAQLFINLMEST 484
Cdd:pfam14643   81 LLRKSWIKELDETLEKLEKERADKLKSVLKKYVEILEDIAHLLPPDVYRLIDKEAMEINQALLENRRAYAKLFANLMEAE 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  485 LQQELDSRHRWQGLVDTWKDLKKEALLQSFSEFMASESIHTPQAVVKELEVMLKTQNVLQQRRLKHLCTICDLLPPNYSK 564
Cdd:pfam14643  161 LKQELSFRLRWQDRVDRWKALKTEHLIQEFKEFIASEEIQNPPERKKELEEMLKEQKKLQQKRLELLQKISDLLPPAYSK 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  565 TQLTEWHSSLNSMNKELDTYHVDCMMRIRLLYEKTWQECLMLVQNCKKQLLDWKAFTEEEAETLVNQFFFQTVGALQGKV 644
Cdd:pfam14643  241 SKVEEWWASLEALNEQLDQYHDQCMTKLRAEYEEVWQECLARVQKLKQELLDYKVCSEEEAEALVNEEFLPLVGKLQRDA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  645 EEDLELLDKSFETLADQTEWQSSNLFRYFQEAVQLWEAHQSKLLVQELELEKRMEQHQQKHSLESQVQEAHLDRLLDQLR 724
Cdd:pfam14643  321 EDELEKLDKFLEELAKQTEAQSEDLFKFFREAAQLWDVHQTELAKQELELEKKLEQCRQKHDQENQAKEAALDKKLDQLR 400
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622872052  725 QQSDKETLAFHLEKVKDYLKNMKSRYEYFHTLLTKEVMEYPAIILKELNSYSSNLSQYFFVREIFEQNL 793
Cdd:pfam14643  401 QASTEEKLKECLDKALKFLDDIEKEYEDFHDKLTAIVKEYPTMILEELESYSTSLSQYFEVREIFEQNL 469
DUF4456 pfam14644
Domain of unknown function (DUF4456); This domain family is found in bacteria and eukaryotes, ...
1514-1718 3.80e-70

Domain of unknown function (DUF4456); This domain family is found in bacteria and eukaryotes, and is approximately 210 amino acids in length. There is a single completely conserved residue E that may be functionally important.


Pssm-ID: 464232  Cd Length: 209  Bit Score: 234.49  E-value: 3.80e-70
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052 1514 LLAVAEEFYR-KEKRPVTRPDCMYDTFDQCAENIGKKILDYQSQANKYHNSCLIELRIQMRRFEELLPQVCWLVMENFKE 1592
Cdd:pfam14644    1 LLSVAEPYYAqKGARPITRPEQIPETFEQCAENIQQKLLSYQEQADEYHNSCLQELRNQVERLEELLPSVPELIFESLLK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052 1593 HHWKMFCTSVKEIRGQFEGQQKQLEKRKDKNAQKLHLNLGHPIHFQEMESLHLSEDKRQEELDSMIRMNREKLEECTRRN 1672
Cdd:pfam14644   81 RHLQKLERAMKNIAAEFSQKQKQLEQLKQQHEQQLRPTLGHPQNAQELEQLCDREEDRQKEHIELIQAHREALLEAVDKV 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1622872052 1673 GQVFITNLAAFTEKFLLQLDEVVTIDDVQVA---RMEPPKQKLSMLIRR 1718
Cdd:pfam14644  161 ASTFVERLASLTEFLLLLFDSLLTPDDLQPLpgdAIEPKRKNLKVLLRR 209
RBP_receptor pfam14752
Retinol binding protein receptor; Proteins in this family function as retinol binding protein ...
42-149 1.68e-45

Retinol binding protein receptor; Proteins in this family function as retinol binding protein receptors.


Pssm-ID: 464298  Cd Length: 603  Bit Score: 175.14  E-value: 1.68e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052   42 KAFHNFNYFLFFYNVLLGLGACLSRLLISCLLGTWLIARIDRTIMQNGYEGADMGFSAWIGMLYVDHYHTNPVLVSFCHI 121
Cdd:pfam14752  459 RALHLFTYLLFFYNVLVGLLACIWRLLISALYNIVHLGRIDRSLLQRGVEALDPGYRTYIGMLKIEVSQSHPVMKAFCGL 538
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1622872052  122 LI------------ANHKEKKLQQTTKYWCLNQSAESLRI 149
Cdd:pfam14752  539 LLqapkpqgraaqkPSDAEEGIQLLQTKKDFNAKGSGPRA 578
 
Name Accession Description Interval E-value
DUF4455 pfam14643
Domain of unknown function (DUF4455); This domain family is found in bacteria and eukaryotes, ...
325-793 0e+00

Domain of unknown function (DUF4455); This domain family is found in bacteria and eukaryotes, and is approximately 480 amino acids in length. There are two completely conserved residues (W and P) that may be functionally important.


Pssm-ID: 464231 [Multi-domain]  Cd Length: 469  Bit Score: 612.36  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  325 AEHKRRSYEGALASFEEEIAQVGKEMEALIVDTAGLFLKKLTESDEEMNRLFLKVENDTNLEDYTIQALLELWDKVARRF 404
Cdd:pfam14643    1 AESRRERHEKALASFEKELASLSNEVEPLIAEAGELLLQKLAESDEEINALFKKLEDDDALEDYTIQQLEELWDIVAQHS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  405 LLQKQEIKELDEALHSLEFSRVNKLKGVLKKYAEVIEKTSYLMRPDVYKLINKEAMVMNYALLGNRKALAQLFINLMEST 484
Cdd:pfam14643   81 LLRKSWIKELDETLEKLEKERADKLKSVLKKYVEILEDIAHLLPPDVYRLIDKEAMEINQALLENRRAYAKLFANLMEAE 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  485 LQQELDSRHRWQGLVDTWKDLKKEALLQSFSEFMASESIHTPQAVVKELEVMLKTQNVLQQRRLKHLCTICDLLPPNYSK 564
Cdd:pfam14643  161 LKQELSFRLRWQDRVDRWKALKTEHLIQEFKEFIASEEIQNPPERKKELEEMLKEQKKLQQKRLELLQKISDLLPPAYSK 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  565 TQLTEWHSSLNSMNKELDTYHVDCMMRIRLLYEKTWQECLMLVQNCKKQLLDWKAFTEEEAETLVNQFFFQTVGALQGKV 644
Cdd:pfam14643  241 SKVEEWWASLEALNEQLDQYHDQCMTKLRAEYEEVWQECLARVQKLKQELLDYKVCSEEEAEALVNEEFLPLVGKLQRDA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052  645 EEDLELLDKSFETLADQTEWQSSNLFRYFQEAVQLWEAHQSKLLVQELELEKRMEQHQQKHSLESQVQEAHLDRLLDQLR 724
Cdd:pfam14643  321 EDELEKLDKFLEELAKQTEAQSEDLFKFFREAAQLWDVHQTELAKQELELEKKLEQCRQKHDQENQAKEAALDKKLDQLR 400
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622872052  725 QQSDKETLAFHLEKVKDYLKNMKSRYEYFHTLLTKEVMEYPAIILKELNSYSSNLSQYFFVREIFEQNL 793
Cdd:pfam14643  401 QASTEEKLKECLDKALKFLDDIEKEYEDFHDKLTAIVKEYPTMILEELESYSTSLSQYFEVREIFEQNL 469
DUF4456 pfam14644
Domain of unknown function (DUF4456); This domain family is found in bacteria and eukaryotes, ...
1514-1718 3.80e-70

Domain of unknown function (DUF4456); This domain family is found in bacteria and eukaryotes, and is approximately 210 amino acids in length. There is a single completely conserved residue E that may be functionally important.


Pssm-ID: 464232  Cd Length: 209  Bit Score: 234.49  E-value: 3.80e-70
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052 1514 LLAVAEEFYR-KEKRPVTRPDCMYDTFDQCAENIGKKILDYQSQANKYHNSCLIELRIQMRRFEELLPQVCWLVMENFKE 1592
Cdd:pfam14644    1 LLSVAEPYYAqKGARPITRPEQIPETFEQCAENIQQKLLSYQEQADEYHNSCLQELRNQVERLEELLPSVPELIFESLLK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052 1593 HHWKMFCTSVKEIRGQFEGQQKQLEKRKDKNAQKLHLNLGHPIHFQEMESLHLSEDKRQEELDSMIRMNREKLEECTRRN 1672
Cdd:pfam14644   81 RHLQKLERAMKNIAAEFSQKQKQLEQLKQQHEQQLRPTLGHPQNAQELEQLCDREEDRQKEHIELIQAHREALLEAVDKV 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1622872052 1673 GQVFITNLAAFTEKFLLQLDEVVTIDDVQVA---RMEPPKQKLSMLIRR 1718
Cdd:pfam14644  161 ASTFVERLASLTEFLLLLFDSLLTPDDLQPLpgdAIEPKRKNLKVLLRR 209
RBP_receptor pfam14752
Retinol binding protein receptor; Proteins in this family function as retinol binding protein ...
42-149 1.68e-45

Retinol binding protein receptor; Proteins in this family function as retinol binding protein receptors.


Pssm-ID: 464298  Cd Length: 603  Bit Score: 175.14  E-value: 1.68e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622872052   42 KAFHNFNYFLFFYNVLLGLGACLSRLLISCLLGTWLIARIDRTIMQNGYEGADMGFSAWIGMLYVDHYHTNPVLVSFCHI 121
Cdd:pfam14752  459 RALHLFTYLLFFYNVLVGLLACIWRLLISALYNIVHLGRIDRSLLQRGVEALDPGYRTYIGMLKIEVSQSHPVMKAFCGL 538
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1622872052  122 LI------------ANHKEKKLQQTTKYWCLNQSAESLRI 149
Cdd:pfam14752  539 LLqapkpqgraaqkPSDAEEGIQLLQTKKDFNAKGSGPRA 578
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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