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Conserved domains on  [gi|1622852109|ref|XP_028686994|]
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collagen alpha-4(IV) chain isoform X3 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1376-1481 7.75e-54

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


:

Pssm-ID: 460201  Cd Length: 110  Bit Score: 183.56  E-value: 7.75e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109 1376 FLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQrNDRSYWLAS 1455
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGNGTCNYAS-NDYSYWLST 79

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1622852109 1456 AA-----PLPMMPLSEEAIRPYVSRCAVCEA 1481
Cdd:pfam01413   80 VEeqfrkPMSQTPKAGNELRSYISRCVVCEA 110
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1484-1596 9.70e-50

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


:

Pssm-ID: 460201  Cd Length: 110  Bit Score: 171.62  E-value: 9.70e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109 1484 QAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTgAGDQGGGQALMSPGSCLEDFRAAPFLECQGRqGTCHFFANEYSFWLT 1563
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHT-GNGEGHGQDLGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLS 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1622852109 1564 TVkaDLQFSSaPAPDTLKESQAQRQKISRCQVC 1596
Cdd:pfam01413   79 TV--EEQFRK-PMSQTPKAGNELRSYISRCVVC 108
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 697-919 1.96e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 89.96  E-value: 1.96e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  697 GYPGAEGPAGIPGFPGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGM 776
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  777 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGfPGFPGERGKPGAEGCPGTKGEPGEKGMSGFPGDQG 856
Cdd:NF038329   197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGD-PGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622852109  857 VRGAKGTIGPPGDEGEMAIISKKGKPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPG 919
Cdd:NF038329   276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 550-787 9.16e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 75.71  E-value: 9.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  550 GHPGVPGRPGVRGPDGLKGQKGDtvscnvtyPGRQGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTSEIPGPP 629
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGD--------RGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPA 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  630 GFRGDIGDPGFGGEKGSSPVGPPGPPGSPgvNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGYPGAEGPAGIPG 709
Cdd:NF038329   189 GEKGPQGPRGETGPAGEQGPAGPAGPDGE--AGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRG 266

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109  710 FPGLKGPKGREGhagfpgvpgppghscergapgipgQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 787
Cdd:NF038329   267 EAGPDGPDGKDG------------------------ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDG 320
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 95-264 5.67e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 73.02  E-value: 5.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109   95 GDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG----VGVKGQMGDPGEVGQQGSPGPTLLVEP 170
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgeAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  171 PDFCLYKGEKGIKGIPGMIGLPGPPGHKGESGIGAKGEKGIPGFPGPWGDPGSYGSPGFPGLKGELGLVGDPGPfgfLGP 250
Cdd:NF038329   197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP---DGP 273

                          170
                   ....*....|....
gi 1622852109  251 KGDPGDRGHPGPPG 264
Cdd:NF038329   274 DGKDGERGPVGPAG 287
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 907-1133 3.34e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 61.07  E-value: 3.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  907 GRRGEPGRYGPPGfYRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 986
Cdd:NF038329   117 GEKGEPGPAGPAG-PAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQG 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  987 PASHFGPPGPKGEPGSSGCPGHFGASGEQGLPGVQGPRGSPGWPGPPGSSGPPG-----------CPGDRGMPGLRGQPG 1055
Cdd:NF038329   196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPqgpdgpagkdgPRGDRGEAGPDGPDG 275

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109 1056 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGlhdvgppgPVGMPGLKGERGDPGSPGISPP 1133
Cdd:NF038329   276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPG--------KDGLPGKDGKDGQPGKPAPKTP 345
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 328-510 8.27e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  328 GEAGiPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVTYCSVGNPGPQGIKGKVGPPGGRGSKGEKGNEGlcacEPGPM 407
Cdd:NF038329   120 GEPG-PAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAG----EKGPQ 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  408 GPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKPGAsGPPGNKGAKGDVVISRVKGHKGERGPDGPPGF 487
Cdd:NF038329   195 GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDP-GPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP 273

                          170       180
                   ....*....|....*....|....*.
gi 1622852109  488 PGQPGSHGLDGHAG---EKGDPGLPG 510
Cdd:NF038329   274 DGKDGERGPVGPAGkdgQNGKDGLPG 299
 
Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1376-1481 7.75e-54

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 183.56  E-value: 7.75e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109 1376 FLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQrNDRSYWLAS 1455
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGNGTCNYAS-NDYSYWLST 79

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1622852109 1456 AA-----PLPMMPLSEEAIRPYVSRCAVCEA 1481
Cdd:pfam01413   80 VEeqfrkPMSQTPKAGNELRSYISRCVVCEA 110
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1484-1596 9.70e-50

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 171.62  E-value: 9.70e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109 1484 QAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTgAGDQGGGQALMSPGSCLEDFRAAPFLECQGRqGTCHFFANEYSFWLT 1563
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHT-GNGEGHGQDLGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLS 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1622852109 1564 TVkaDLQFSSaPAPDTLKESQAQRQKISRCQVC 1596
Cdd:pfam01413   79 TV--EEQFRK-PMSQTPKAGNELRSYISRCVVC 108
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1375-1482 1.16e-45

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 160.25  E-value: 1.16e-45
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  1375 GFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLA 1454
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGRGVCNYASRNDYSFWLS 80

                            90       100       110
                    ....*....|....*....|....*....|....*
gi 1622852109  1455 S-------AAPLPMMPLSEEaIRPYVSRCAVCEAP 1482
Cdd:smart00111   81 TiepsdqfTAPRPMTPKAGD-LRPYISRCQVCEKP 114
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1483-1598 2.03e-42

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 151.00  E-value: 2.03e-42
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  1483 AQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFA-NEYSFW 1561
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQD-LGSPGSCLERFRTMPFIECNGR-GVCNYASrNDYSFW 78

                            90       100       110
                    ....*....|....*....|....*....|....*..
gi 1622852109  1562 LTTVKADLQFsSAPAPDTLKESQAqRQKISRCQVCVK 1598
Cdd:smart00111   79 LSTIEPSDQF-TAPRPMTPKAGDL-RPYISRCQVCEK 113
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 697-919 1.96e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 89.96  E-value: 1.96e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  697 GYPGAEGPAGIPGFPGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGM 776
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  777 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGfPGFPGERGKPGAEGCPGTKGEPGEKGMSGFPGDQG 856
Cdd:NF038329   197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGD-PGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622852109  857 VRGAKGTIGPPGDEGEMAIISKKGKPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPG 919
Cdd:NF038329   276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 550-787 9.16e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 75.71  E-value: 9.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  550 GHPGVPGRPGVRGPDGLKGQKGDtvscnvtyPGRQGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTSEIPGPP 629
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGD--------RGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPA 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  630 GFRGDIGDPGFGGEKGSSPVGPPGPPGSPgvNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGYPGAEGPAGIPG 709
Cdd:NF038329   189 GEKGPQGPRGETGPAGEQGPAGPAGPDGE--AGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRG 266

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109  710 FPGLKGPKGREGhagfpgvpgppghscergapgipgQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 787
Cdd:NF038329   267 EAGPDGPDGKDG------------------------ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDG 320
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 95-264 5.67e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 73.02  E-value: 5.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109   95 GDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG----VGVKGQMGDPGEVGQQGSPGPTLLVEP 170
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgeAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  171 PDFCLYKGEKGIKGIPGMIGLPGPPGHKGESGIGAKGEKGIPGFPGPWGDPGSYGSPGFPGLKGELGLVGDPGPfgfLGP 250
Cdd:NF038329   197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP---DGP 273

                          170
                   ....*....|....
gi 1622852109  251 KGDPGDRGHPGPPG 264
Cdd:NF038329   274 DGKDGERGPVGPAG 287
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 2-262 3.66e-10

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.16  E-value: 3.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109    2 RGDRGPPGTAGDKGDKGPTGVPGFPGLDGIPGHPGPPgprGKPGKCGYNGSRGDPGfpggrgalgpggppghpgekgekg 81
Cdd:NF038329   137 RGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQ---GPAGKDGEAGAKGPAG------------------------ 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109   82 nsvfilgaIKGIQGDRGDPGLPGLPGSwgaggpagptgyPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGS 161
Cdd:NF038329   190 --------EKGPQGPRGETGPAGEQGP------------AGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGP 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  162 PGPTLLVEPpdfclyKGEKGIKGIPGMIGLPGPPGHKGESGIGAK-GEKGIPGFPGPWGDPGSYGSPGFPGLKGELGLvg 240
Cdd:NF038329   250 QGPDGPAGK------DGPRGDRGEAGPDGPDGKDGERGPVGPAGKdGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQ-- 321

                          250       260
                   ....*....|....*....|..
gi 1622852109  241 dPGPFGFLGPKGDPGDRGHPGP 262
Cdd:NF038329   322 -PGKDGLPGKDGKDGQPGKPAP 342
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 907-1133 3.34e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 61.07  E-value: 3.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  907 GRRGEPGRYGPPGfYRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 986
Cdd:NF038329   117 GEKGEPGPAGPAG-PAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQG 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  987 PASHFGPPGPKGEPGSSGCPGHFGASGEQGLPGVQGPRGSPGWPGPPGSSGPPG-----------CPGDRGMPGLRGQPG 1055
Cdd:NF038329   196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPqgpdgpagkdgPRGDRGEAGPDGPDG 275

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109 1056 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGlhdvgppgPVGMPGLKGERGDPGSPGISPP 1133
Cdd:NF038329   276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPG--------KDGLPGKDGKDGQPGKPAPKTP 345
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 328-510 8.27e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  328 GEAGiPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVTYCSVGNPGPQGIKGKVGPPGGRGSKGEKGNEGlcacEPGPM 407
Cdd:NF038329   120 GEPG-PAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAG----EKGPQ 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  408 GPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKPGAsGPPGNKGAKGDVVISRVKGHKGERGPDGPPGF 487
Cdd:NF038329   195 GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDP-GPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP 273

                          170       180
                   ....*....|....*....|....*.
gi 1622852109  488 PGQPGSHGLDGHAG---EKGDPGLPG 510
Cdd:NF038329   274 DGKDGERGPVGPAGkdgQNGKDGLPG 299
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 737-788 5.47e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 45.18  E-value: 5.47e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622852109  737 ERGAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 788
Cdd:pfam01391    2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 387-720 3.37e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 3.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  387 GRGSKGEKGNEGlcacepgpmgPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKPGASGPPGNKGAKGD 466
Cdd:NF038329   115 GDGEKGEPGPAG----------PAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGA 184

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  467 VVISRVKGHKGERGPDGPPGFPGQPGSHGLDGHAGEKGDPGLPGDHEDaiaggkgfpgplgppgkagpvgppglgfpgpp 546
Cdd:NF038329   185 KGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGD-------------------------------- 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  547 gerghpGVPGRPGVRGPDGLKGQKGDTvscnvtypgrqgppgfdgppgpkgfpgpqgapGLSGSDGHKGRPGTPGTSEIP 626
Cdd:NF038329   233 ------GQQGPDGDPGPTGEDGPQGPD--------------------------------GPAGKDGPRGDRGEAGPDGPD 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  627 GPPGFRGDIGDPGFGGEkgsspvgppgppgspgvNGQKGIPGDPafghlGPPGKRGLSGVPGIKGPRGDPGYPGAEGPAG 706
Cdd:NF038329   275 GKDGERGPVGPAGKDGQ-----------------NGKDGLPGKD-----GKDGQNGKDGLPGKDGKDGQPGKDGLPGKDG 332

                          330
                   ....*....|....
gi 1622852109  707 IPGFPGLKGPKGRE 720
Cdd:NF038329   333 KDGQPGKPAPKTPE 346
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
676-871 5.54e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 41.17  E-value: 5.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  676 GPPGKRGLSGVPGIKGPRGDPGYPGAEGPAGIPGFPGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGDPGS 755
Cdd:COG5164     10 GPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  756 PGAP---GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 832
Cdd:COG5164     90 TRPAgntGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGSTTPPGDGGSTTPPG 169

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1622852109  833 AEGCPGTKGEPGEKGmSGFPGDQGVRGAKGTIGPPGDEG 871
Cdd:COG5164    170 PGGSTTPPDDGGSTT-PPNKGETGTDIPTGGTPRQGPDG 207
 
Name Accession Description Interval E-value
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1376-1481 7.75e-54

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 183.56  E-value: 7.75e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109 1376 FLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQrNDRSYWLAS 1455
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGNGTCNYAS-NDYSYWLST 79

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1622852109 1456 AA-----PLPMMPLSEEAIRPYVSRCAVCEA 1481
Cdd:pfam01413   80 VEeqfrkPMSQTPKAGNELRSYISRCVVCEA 110
C4 pfam01413
C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of ...
 1484-1596 9.70e-50

C-terminal tandem repeated domain in type 4 procollagen; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 460201  Cd Length: 110  Bit Score: 171.62  E-value: 9.70e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109 1484 QAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTgAGDQGGGQALMSPGSCLEDFRAAPFLECQGRqGTCHFFANEYSFWLT 1563
Cdd:pfam01413    1 FLIAVHSQTTQIPDCPPGWTSLWTGYSLLMHT-GNGEGHGQDLGSPGSCLERFRTMPFIECNGN-GTCNYASNDYSYWLS 78

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1622852109 1564 TVkaDLQFSSaPAPDTLKESQAQRQKISRCQVC 1596
Cdd:pfam01413   79 TV--EEQFRK-PMSQTPKAGNELRSYISRCVVC 108
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1375-1482 1.16e-45

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 160.25  E-value: 1.16e-45
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  1375 GFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLA 1454
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQDLGSPGSCLERFRTMPFIECNGRGVCNYASRNDYSFWLS 80

                            90       100       110
                    ....*....|....*....|....*....|....*
gi 1622852109  1455 S-------AAPLPMMPLSEEaIRPYVSRCAVCEAP 1482
Cdd:smart00111   81 TiepsdqfTAPRPMTPKAGD-LRPYISRCQVCEKP 114
C4 smart00111
C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of ...
 1483-1598 2.03e-42

C-terminal tandem repeated domain in type 4 procollagens; Duplicated domain in C-terminus of type 4 collagens. Mutations in alpha-5 collagen IV are associated with X-linked Alport syndrome.


Pssm-ID: 128421  Cd Length: 114  Bit Score: 151.00  E-value: 2.03e-42
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  1483 AQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQaLMSPGSCLEDFRAAPFLECQGRqGTCHFFA-NEYSFW 1561
Cdd:smart00111    1 GFVIAVHSQTTNVPQCPAGWVELWTGYSFLMHTGNGEGHGQD-LGSPGSCLERFRTMPFIECNGR-GVCNYASrNDYSFW 78

                            90       100       110
                    ....*....|....*....|....*....|....*..
gi 1622852109  1562 LTTVKADLQFsSAPAPDTLKESQAqRQKISRCQVCVK 1598
Cdd:smart00111   79 LSTIEPSDQF-TAPRPMTPKAGDL-RPYISRCQVCEK 113
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 697-919 1.96e-18

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 89.96  E-value: 1.96e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  697 GYPGAEGPAGIPGFPGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGM 776
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  777 KGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGfPGFPGERGKPGAEGCPGTKGEPGEKGMSGFPGDQG 856
Cdd:NF038329   197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGD-PGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622852109  857 VRGAKGTIGPPGDEGEMAIISKKGKPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPG 919
Cdd:NF038329   276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 550-787 9.16e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 75.71  E-value: 9.16e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  550 GHPGVPGRPGVRGPDGLKGQKGDtvscnvtyPGRQGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTSEIPGPP 629
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGD--------RGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPA 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  630 GFRGDIGDPGFGGEKGSSPVGPPGPPGSPgvNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGYPGAEGPAGIPG 709
Cdd:NF038329   189 GEKGPQGPRGETGPAGEQGPAGPAGPDGE--AGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRG 266

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109  710 FPGLKGPKGREGhagfpgvpgppghscergapgipgQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 787
Cdd:NF038329   267 EAGPDGPDGKDG------------------------ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDG 320
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 95-264 5.67e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 73.02  E-value: 5.67e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109   95 GDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG----VGVKGQMGDPGEVGQQGSPGPTLLVEP 170
Cdd:NF038329   117 GEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgeAGPQGPAGKDGEAGAKGPAGEKGPQGP 196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  171 PDFCLYKGEKGIKGIPGMIGLPGPPGHKGESGIGAKGEKGIPGFPGPWGDPGSYGSPGFPGLKGELGLVGDPGPfgfLGP 250
Cdd:NF038329   197 RGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGP---DGP 273

                          170
                   ....*....|....
gi 1622852109  251 KGDPGDRGHPGPPG 264
Cdd:NF038329   274 DGKDGERGPVGPAG 287
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 2-262 3.66e-10

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.16  E-value: 3.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109    2 RGDRGPPGTAGDKGDKGPTGVPGFPGLDGIPGHPGPPgprGKPGKCGYNGSRGDPGfpggrgalgpggppghpgekgekg 81
Cdd:NF038329   137 RGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQ---GPAGKDGEAGAKGPAG------------------------ 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109   82 nsvfilgaIKGIQGDRGDPGLPGLPGSwgaggpagptgyPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGS 161
Cdd:NF038329   190 --------EKGPQGPRGETGPAGEQGP------------AGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGP 249

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  162 PGPTLLVEPpdfclyKGEKGIKGIPGMIGLPGPPGHKGESGIGAK-GEKGIPGFPGPWGDPGSYGSPGFPGLKGELGLvg 240
Cdd:NF038329   250 QGPDGPAGK------DGPRGDRGEAGPDGPDGKDGERGPVGPAGKdGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQ-- 321

                          250       260
                   ....*....|....*....|..
gi 1622852109  241 dPGPFGFLGPKGDPGDRGHPGP 262
Cdd:NF038329   322 -PGKDGLPGKDGKDGQPGKPAP 342
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 907-1133 3.34e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 61.07  E-value: 3.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  907 GRRGEPGRYGPPGfYRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 986
Cdd:NF038329   117 GEKGEPGPAGPAG-PAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQG 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  987 PASHFGPPGPKGEPGSSGCPGHFGASGEQGLPGVQGPRGSPGWPGPPGSSGPPG-----------CPGDRGMPGLRGQPG 1055
Cdd:NF038329   196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPqgpdgpagkdgPRGDRGEAGPDGPDG 275

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109 1056 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGlhdvgppgPVGMPGLKGERGDPGSPGISPP 1133
Cdd:NF038329   276 KDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPG--------KDGLPGKDGKDGQPGKPAPKTP 345
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 328-510 8.27e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 53.37  E-value: 8.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  328 GEAGiPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVTYCSVGNPGPQGIKGKVGPPGGRGSKGEKGNEGlcacEPGPM 407
Cdd:NF038329   120 GEPG-PAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAG----EKGPQ 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  408 GPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKPGAsGPPGNKGAKGDVVISRVKGHKGERGPDGPPGF 487
Cdd:NF038329   195 GPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDP-GPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP 273

                          170       180
                   ....*....|....*....|....*.
gi 1622852109  488 PGQPGSHGLDGHAG---EKGDPGLPG 510
Cdd:NF038329   274 DGKDGERGPVGPAGkdgQNGKDGLPG 299
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 737-788 5.47e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 45.18  E-value: 5.47e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622852109  737 ERGAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 788
Cdd:pfam01391    2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGA 53
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 739-788 2.60e-05

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 43.25  E-value: 2.60e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622852109  739 GAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 788
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGA 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 387-720 3.37e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 3.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  387 GRGSKGEKGNEGlcacepgpmgPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKPGASGPPGNKGAKGD 466
Cdd:NF038329   115 GDGEKGEPGPAG----------PAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGA 184

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  467 VVISRVKGHKGERGPDGPPGFPGQPGSHGLDGHAGEKGDPGLPGDHEDaiaggkgfpgplgppgkagpvgppglgfpgpp 546
Cdd:NF038329   185 KGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGD-------------------------------- 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  547 gerghpGVPGRPGVRGPDGLKGQKGDTvscnvtypgrqgppgfdgppgpkgfpgpqgapGLSGSDGHKGRPGTPGTSEIP 626
Cdd:NF038329   233 ------GQQGPDGDPGPTGEDGPQGPD--------------------------------GPAGKDGPRGDRGEAGPDGPD 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  627 GPPGFRGDIGDPGFGGEkgsspvgppgppgspgvNGQKGIPGDPafghlGPPGKRGLSGVPGIKGPRGDPGYPGAEGPAG 706
Cdd:NF038329   275 GKDGERGPVGPAGKDGQ-----------------NGKDGLPGKD-----GKDGQNGKDGLPGKDGKDGQPGKDGLPGKDG 332

                          330
                   ....*....|....
gi 1622852109  707 IPGFPGLKGPKGRE 720
Cdd:NF038329   333 KDGQPGKPAPKTPE 346
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 694-765 2.07e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 2.07e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622852109  694 GDPGYPGAEGPAGIPGFPGLKGPKGREGHagfpgvpgppghsceRGAPGIPGQPGLPGDPGSPGAPGGKGQP 765
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGP---------------PGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 688-760 2.35e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 2.35e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622852109  688 GIKGPRGDPGYPGAEGPAGIPGFPGLKGPKGreghagfpgvpgppghscERGAPGIPGQPGLPGDPGSPGAPG 760
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPG------------------EPGPPGPPGPPGPPGPPGAPGAPG 55
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 697-774 2.52e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.47  E-value: 2.52e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622852109  697 GYPGAEGPAGIPGFPGLKGPkgreghagfpgvpgppghsceRGAPGIPGQPGLPGDPGSPGAPGGKGQPGDVGPPGPA 774
Cdd:pfam01391    1 GPPGPPGPPGPPGPPGPPGP---------------------PGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
676-871 5.54e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 41.17  E-value: 5.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  676 GPPGKRGLSGVPGIKGPRGDPGYPGAEGPAGIPGFPGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGDPGS 755
Cdd:COG5164     10 GPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQGG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622852109  756 PGAP---GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 832
Cdd:COG5164     90 TRPAgntGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGSTTPPGDGGSTTPPG 169

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1622852109  833 AEGCPGTKGEPGEKGmSGFPGDQGVRGAKGTIGPPGDEG 871
Cdd:COG5164    170 PGGSTTPPDDGGSTT-PPNKGETGTDIPTGGTPRQGPDG 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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