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Conserved domains on  [gi|1622850714|ref|XP_028686768|]
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3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X2 [Macaca mulatta]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-349 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 554.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  19 AGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV-FFREEYML 97
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  98 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 177
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 178 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFMLEEHMDKINSCFSANTMEEIIENL 257
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 258 KQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 335
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 1622850714 336 DLKEVTDEDLNNHF 349
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-349 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 554.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  19 AGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV-FFREEYML 97
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  98 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 177
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 178 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFMLEEHMDKINSCFSANTMEEIIENL 257
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 258 KQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 335
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 1622850714 336 DLKEVTDEDLNNHF 349
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
7-351 4.20e-159

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 449.27  E-value: 4.20e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   7 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNI 86
Cdd:PRK05617    1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  87 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 165
Cdd:PRK05617   81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 166 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfmLEEHMDKINSC 244
Cdd:PRK05617  161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 245 FSANTMEEIIENLKQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLI 324
Cdd:PRK05617  236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLI 315
                         330       340
                  ....*....|....*....|....*..
gi 1622850714 325 DKDQSPKWKPADLKEVTDEDLNNHFKS 351
Cdd:PRK05617  316 DKDRNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
11-195 6.22e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 193.93  E-value: 6.22e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApVF 90
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 169
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                         170       180
                  ....*....|....*....|....*.
gi 1622850714 170 LTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
11-323 1.38e-52

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 174.20  E-value: 1.38e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApvF 90
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEEARA--F 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 169
Cdd:COG1024    78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 170 LTGFRLKGRDVYRAGIATHFVDSEKLamleedllalkspskeniasvlenyhteskidrdksfmleehmdkinscfsant 249
Cdd:COG1024   158 LTGRRIDAEEALELGLVNRVVPDDEL------------------------------------------------------ 183
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622850714 250 MEEiienlkqdgssfALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 323
Cdd:COG1024   184 LAA------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
3-195 2.14e-15

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 75.27  E-value: 2.14e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   3 KHTDAAADvllekkgcagvITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV------I 76
Cdd:TIGR01929   8 KSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVrgdygyI 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  77 SEAEKAKQNIAPVffreeymlNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 156
Cdd:TIGR01929  77 DDSGVHRLNVLDV--------QRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSY 148
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1622850714 157 LPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:TIGR01929 149 MARIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-349 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 554.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  19 AGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV-FFREEYML 97
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRdFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  98 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 177
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 178 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKidrDKSFMLEEHMDKINSCFSANTMEEIIENL 257
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESD---PPPSPLAAHREAIDRCFSADTVEEIIAAL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 258 KQ--DGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPA 335
Cdd:pfam16113 238 EAeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPA 317
                         330
                  ....*....|....
gi 1622850714 336 DLKEVTDEDLNNHF 349
Cdd:pfam16113 318 TLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
7-351 4.20e-159

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 449.27  E-value: 4.20e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   7 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNI 86
Cdd:PRK05617    1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  87 A-PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLG 165
Cdd:PRK05617   81 AaDRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 166 YFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKE-NIASVLENYHTESKIDRdksfmLEEHMDKINSC 244
Cdd:PRK05617  161 TYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGAdVVDAALAAFATPAPASE-----LAAQRAWIDEC 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 245 FSANTMEEIIENLKQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLI 324
Cdd:PRK05617  236 FAGDTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLI 315
                         330       340
                  ....*....|....*....|....*..
gi 1622850714 325 DKDQSPKWKPADLKEVTDEDLNNHFKS 351
Cdd:PRK05617  316 DKDRNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
11-350 1.15e-112

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 332.92  E-value: 1.15e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVF 90
Cdd:PLN02874   13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGRESDDSCLEVV 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREeYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLAL 170
Cdd:PLN02874   92 YRM-YWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGHLGEYLAL 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 171 TGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFmleEHMDKINSCFSANTM 250
Cdd:PLN02874  171 TGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFSKDVQADEDSIL---NKQSWINECFSKDTV 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 251 EEIIENL----KQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRG---HDFHEGVRAVL 323
Cdd:PLN02874  248 EEIIKAFeseaSKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNILRStvsDDVYEGIRALV 327
                         330       340
                  ....*....|....*....|....*..
gi 1622850714 324 IDKDQSPKWKPADLKEVTDEDLNNHFK 350
Cdd:PLN02874  328 IDKDNAPKWNPSTLDEVTDEKVDLVFQ 354
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-350 2.15e-92

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 281.22  E-value: 2.15e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIR-VISEA 79
Cdd:PLN02988    1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKG-HGRAFCAGGDVAaVVRDI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  80 EKAKQNIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 159
Cdd:PLN02988   80 EQGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 160 LQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFmleEHMD 239
Cdd:PLN02988  160 LPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAY---HRLD 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 240 KINSCFSANTMEEIIENLK----QDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGH-- 313
Cdd:PLN02988  237 VIDRCFSRRTVEEIISALEreatQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEis 316
                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1622850714 314 -DFHEGVRAVLIDKDQSPKWKPADLKEVTDEDLNNHFK 350
Cdd:PLN02988  317 kDFVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFE 354
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
2-356 8.96e-85

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 262.61  E-value: 8.96e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   2 SKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEA-E 80
Cdd:PLN02851   35 AANDDLQDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADVVSLYHLiN 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  81 KAKQNIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRL 160
Cdd:PLN02851  114 EGNVEECKLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRL 193
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 161 QGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHteSKIDRDKSFMLEEhMDK 240
Cdd:PLN02851  194 PGYLGEYLALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQYG--DLVYPDKSSVLHK-IET 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 241 INSCFSANTMEEIIENLKQDGSS----FALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMR---GH 313
Cdd:PLN02851  271 IDKCFGHDTVEEIIEALENEAASsydeWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLAREYRISLCGVSkwvSG 350
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1622850714 314 DFHEGVRAVLIDKDQSPKWKPADLKEVTDEDLNNHFKSLGSND 356
Cdd:PLN02851  351 DFCEGVRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPLDESE 393
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
6-352 3.12e-81

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 253.45  E-value: 3.12e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   6 DAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAE-KAKQ 84
Cdd:PLN02157   34 DLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSLYHLRkRGSP 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  85 NIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL 164
Cdd:PLN02157  113 DAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRL 192
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 165 GYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYhteSKIDRDKSFMLEEHMDKINSC 244
Cdd:PLN02157  193 GEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESCLEKC---AEVAHPEKTGVIRRIDLLEKC 269
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 245 FSANTMEEIIENLKQDGS----SFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRG---HDFHE 317
Cdd:PLN02157  270 FSHDTVEEIIDSLEIEAGrrkdTWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLIGpmsGNFCE 349
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1622850714 318 GVRAVLIDKDQSPKWKPADLKEVTDEDLNNHFKSL 352
Cdd:PLN02157  350 GVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCAL 384
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
11-195 6.22e-61

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 193.93  E-value: 6.22e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApVF 90
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEAR-AF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 169
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpARARELL 158
                         170       180
                  ....*....|....*....|....*.
gi 1622850714 170 LTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
11-323 1.38e-52

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 174.20  E-value: 1.38e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApvF 90
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAADPEEARA--F 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 169
Cdd:COG1024    78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlARAKELL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 170 LTGFRLKGRDVYRAGIATHFVDSEKLamleedllalkspskeniasvlenyhteskidrdksfmleehmdkinscfsant 249
Cdd:COG1024   158 LTGRRIDAEEALELGLVNRVVPDDEL------------------------------------------------------ 183
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622850714 250 MEEiienlkqdgssfALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 323
Cdd:COG1024   184 LAA------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
7-323 8.57e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 130.76  E-value: 8.57e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   7 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKA-KQN 85
Cdd:PRK06688    3 MVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGR-AFSAGGDIKDFPKAPPKpPDE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  86 IAPVFfreeyMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLqgkLG 165
Cdd:PRK06688   82 LAPVN-----RFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRL---IG 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 166 YF----LALTGFRLKGRDVYRAGIATHFVDSEKLAmleedllalkspskeniasvlenyhteskidrdksfmleehmdki 241
Cdd:PRK06688  154 RAraaeMLLLGEPLSAEEALRIGLVNRVVPAAELD--------------------------------------------- 188
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 242 nscfsantmeeiienlkqdgsSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRA 321
Cdd:PRK06688  189 ---------------------AEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATA 247

                  ..
gi 1622850714 322 VL 323
Cdd:PRK06688  248 FI 249
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
10-214 7.22e-27

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 107.14  E-value: 7.22e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  10 DVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS-----EAEKAKQ 84
Cdd:PRK05809    5 NVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKdlneeEGRKFGL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  85 NIAPVFFREEYMlnnavgscQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 163
Cdd:PRK05809   85 LGNKVFRKLENL--------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGpG 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622850714 164 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKLaMLEEDLLALKSPSKENIA 214
Cdd:PRK05809  157 KAKELIYTGDMINAEEALRIGLVNKVVEPEKL-MEEAKALANKIAANAPIA 206
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
20-218 3.30e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 105.20  E-value: 3.30e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  20 GVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDI--RVISEAEKAKQNIAPVffrEEYMl 97
Cdd:PRK07657   15 VKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLkeRAGMNEEQVRHAVSLI---RTTM- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  98 nNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLK 176
Cdd:PRK07657   91 -EMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRIS 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1622850714 177 GRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIASVLE 218
Cdd:PRK07657  170 AQEAKEIGLVEFVVPAHLLEEKAIEIaekIASNGPiavrqAKEAISNGIQ 219
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
1-204 6.88e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 104.40  E-value: 6.88e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDirvISEAE 80
Cdd:PRK06127    3 MSSISSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGAD---ISQFE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  81 KAKQNIAPVFFREEYMLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdvGGGY-FL 157
Cdd:PRK06127   80 ESRSDAEAVAAYEQAVEAaqAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL----GYGYdGV 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622850714 158 PRLQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA 204
Cdd:PRK06127  156 KNLVDLVGPSAAkdlfYTARRFDAAEALRIGLVHRVTAADDLETALADYAA 206
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-195 9.44e-26

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 103.59  E-value: 9.44e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  14 EKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAKQNIapvfFRE 93
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQAL----YRE 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  94 EYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALT 171
Cdd:pfam00378  76 NVLdLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLL 155
                         170       180
                  ....*....|....*....|....
gi 1622850714 172 GFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:pfam00378 156 GRRISAQEALKWGLVDKVVPEDQL 179
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
11-185 1.35e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 103.32  E-value: 1.35e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE--AEKAKQNIAP 88
Cdd:PRK06072    2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPdfAIDLRETFYP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  89 VFfREeymlnnaVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFL 168
Cdd:PRK06072   81 II-RE-------IRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEI 152
                         170
                  ....*....|....*..
gi 1622850714 169 ALTGFRLKGRDVYRAGI 185
Cdd:PRK06072  153 LVLGGEFTAEEAERWGL 169
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
5-193 5.57e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 102.05  E-value: 5.57e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   5 TDAAADVLLEKKGCAGV--ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKA 82
Cdd:PRK08138    2 MSTATDVVLLERPADGValLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATAGAI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  83 KqniapVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 162
Cdd:PRK08138   81 E-----MYLRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVG 155
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850714 163 KL-GYFLALTGFRLKGRDVYRAGIATHFVDSE 193
Cdd:PRK08138  156 KFkAMRMALTGCMVPAPEALAIGLVSEVVEDE 187
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
11-172 7.31e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 101.76  E-value: 7.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPV- 89
Cdd:PRK05980    5 VLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVALRd 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  90 FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFL 168
Cdd:PRK05980   85 FVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrKRALEL 164

                  ....
gi 1622850714 169 ALTG 172
Cdd:PRK05980  165 LLTG 168
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
11-218 8.77e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 101.27  E-value: 8.77e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRviSEAEKAKQNIAPVF 90
Cdd:PRK06494    6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLK--EQAAGGKRGWPESG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FreeymlnnavGS------CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR---LQ 161
Cdd:PRK06494   84 F----------GGltsrfdLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRqigLK 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622850714 162 GKLGYFlaLTGFRLKGRDVYRAGIATHFV-DSEKLAMLE---EDLLALkSP-----SKENIASVLE 218
Cdd:PRK06494  154 RAMGMI--LTGRRVTAREGLELGFVNEVVpAGELLAAAErwaDDILAC-SPlsiraSKQAVYRGLE 216
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
11-204 2.60e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 100.12  E-value: 2.60e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviseaEKAKQNIAPVf 90
Cdd:PRK05862    6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIK-----EMADLSFMDV- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLN-NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-L 168
Cdd:PRK05862   79 YKGDYITNwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMdL 158
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622850714 169 ALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDLLA 204
Cdd:PRK05862  159 CLTGRMMDAAEAERAGLVSRVVPADKL--LDEALAA 192
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
21-208 1.39e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 89.75  E-value: 1.39e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  21 VITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEK------AKQNIAPVFFree 94
Cdd:PRK06495   16 VVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKgpgdlrAHNRRTRECF--- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  95 ymlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdVGGGYFLPRLQGK-LGYFLALTGF 173
Cdd:PRK06495   91 ----HAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHsLTRRMMLTGY 163
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1622850714 174 RLKGRDVYRAGIATHFVDSEKL---AMLEEDLLALKSP 208
Cdd:PRK06495  164 RVPAAELYRRGVIEACLPPEELmpeAMEIAREIASKSP 201
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
13-218 1.42e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 89.69  E-value: 1.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  13 LEKKGCAGVITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVI------SEAEKAKQNI 86
Cdd:PRK07658    6 VRVEDHVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFtsvteaEQATELAQLG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  87 APVFFREEymlnnavgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-G 165
Cdd:PRK07658   84 QVTFERVE--------KFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAkA 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850714 166 YFLALTGFRLKGRDVYRAGIATHFVDSEKLamLEEDL-----LALKSPskENIASVLE 218
Cdd:PRK07658  156 LEMMLTSEPITGAEALKWGLVNGVFPEETL--LDDAKklakkIAGKSP--ATTRAVLE 209
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
11-209 5.80e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 88.06  E-value: 5.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDI---RVISEAEKAKQNIA 87
Cdd:PRK05995    6 LEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDENRAD 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  88 PVFFREeyMLNnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVgggyFLPRLQGKLG-- 165
Cdd:PRK05995   85 ARRLAD--MLR-AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPAT----ISPYVIRAMGer 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622850714 166 ----YFlaLTGFRLKGRDVYRAGIATHFVDSEKL-AMLEEDLLAL--KSPS 209
Cdd:PRK05995  158 aarrYF--LTAERFDAAEALRLGLVHEVVPAEALdAKVDELLAALvaNSPQ 206
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
11-195 6.38e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 87.72  E-value: 6.38e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE------AEKAKQ 84
Cdd:PRK06190    6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGA-DPAFCAGLDLKELGGdgsaygAQDALP 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  85 NIAPvffreeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 163
Cdd:PRK06190   85 NPSP-----------AWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGiG 153
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850714 164 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:PRK06190  154 RARRMSLTGDFLDAADALRAGLVTEVVPHDEL 185
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
11-199 9.06e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 87.09  E-value: 9.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEA--EKAKQNIAP 88
Cdd:PRK05870    5 VLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGAApgRPAEDGLRR 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  89 VFfrEEYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYF 167
Cdd:PRK05870   84 IY--DGFL---AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGpQVARA 158
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850714 168 LALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 199
Cdd:PRK05870  159 ALLFGMRFDAEAAVRHGLALMVADDPVAAALE 190
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
22-208 1.17e-19

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 87.13  E-value: 1.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRviseaEKAKQNIAPVFFREEYMLNNAV 101
Cdd:PRK09674   15 LTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNA-RFFAAGADLN-----EMAEKDLAATLNDPRPQLWQRL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 102 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDV 180
Cdd:PRK09674   89 QAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKsLASQMVLTGESITAQQA 168
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1622850714 181 YRAGIATHFVDSE---KLAMLEEDLLALKSP 208
Cdd:PRK09674  169 QQAGLVSEVFPPEltlERALQLASKIARHSP 199
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
4-141 2.70e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 86.20  E-value: 2.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   4 HTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAK 83
Cdd:PRK06144    3 MTTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAE 82
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850714  84 QNIAPVFFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 141
Cdd:PRK06144   83 DAVAYERRIDRVL--GALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
22-195 3.85e-19

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 85.90  E-value: 3.85e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPVFF---REEYMLN 98
Cdd:PRK03580   16 ITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFaglTEIFDLD 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  99 navgscqKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFR 174
Cdd:PRK03580   95 -------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPK---RLPPAIAnemvMTGRR 164
                         170       180
                  ....*....|....*....|.
gi 1622850714 175 LKGRDVYRAGIATHFVDSEKL 195
Cdd:PRK03580  165 MDAEEALRWGIVNRVVPQAEL 185
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
22-208 5.09e-19

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 85.72  E-value: 5.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISE-------------AEKAKQNIAp 88
Cdd:PLN02664   21 LNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKTLNSiseqsssgdrgrsGERLRRKIK- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  89 vfFREEYMlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYF- 167
Cdd:PLN02664   99 --FLQDAI--TAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGYGn 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1622850714 168 ---LALTGFRLKGRDVYRAG-IATHFVDSEKL---AMLEEDLLALKSP 208
Cdd:PLN02664  172 ameLALTGRRFSGSEAKELGlVSRVFGSKEDLdegVRLIAEGIAAKSP 219
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
11-195 4.17e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 80.01  E-value: 4.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLN-MIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAkQNIAPV 89
Cdd:PRK09245    5 LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDMRARVGA-FGGSPA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  90 FFREEY-----MLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 163
Cdd:PRK09245   83 DIRQGYrhgiqRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGmA 162
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850714 164 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:PRK09245  163 RAAEMAFTGDAIDAATALEWGLVSRVVPADQL 194
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
8-191 1.63e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 78.22  E-value: 1.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   8 AADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQnia 87
Cdd:PRK07799    4 GPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG-AFCAGMDLKAATKKPPGDS--- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  88 pvfFRE--------EYMLNNAvgSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpR 159
Cdd:PRK07799   80 ---FKDgsydpsriDALLKGR--RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAV--R 151
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622850714 160 LQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVD 191
Cdd:PRK07799  152 LVRQIPYTVAcdllLTGRHITAAEAKEIGLIGHVVP 187
PLN02600 PLN02600
enoyl-CoA hydratase
21-190 3.04e-16

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 77.54  E-value: 3.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  21 VITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV-----ISEAEKAKQNIAPVFfreey 95
Cdd:PLN02600    7 ELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKErrkmsPSEVQKFVNSLRSTF----- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  96 mlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFR 174
Cdd:PLN02600   82 ---SSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRsRAKELIFTGRR 158
                         170
                  ....*....|....*.
gi 1622850714 175 LKGRDVYRAGIATHFV 190
Cdd:PLN02600  159 IGAREAASMGLVNYCV 174
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
11-215 1.12e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 75.84  E-value: 1.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDpETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVF 90
Cdd:PRK07659    8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAES-SAHIVVLRGNG-RGFSAGGDIKMMLSSNDESKFDGVMN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA- 169
Cdd:PRK07659   86 TISEIVV--TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK---RVGENKAk 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1622850714 170 ---LTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLA-LKSPSKENIAS 215
Cdd:PRK07659  161 qiiWEGKKLSATEALDLGLIDEVIGGDFQTAAKQKISEwLQKPLKAMIET 210
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
21-209 1.19e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 75.90  E-value: 1.19e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  21 VITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDI---RVISEAEKAKQNIAPVFF---REE 94
Cdd:PRK06210   18 VITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGA-GRGFCAGADMgelQTIDPSDGRRDTDVRPFVgnrRPD 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  95 YMLNNA-VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LALTG 172
Cdd:PRK06210   97 YQTRYHfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALdLLLSA 176
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1622850714 173 FRLKGRDVYRAGIATHFVDSEKL--AMLE--EDLLALKSPS 209
Cdd:PRK06210  177 RTFYAEEALRLGLVNRVVPPDELmeRTLAyaEDLARNVSPA 217
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
22-162 2.11e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 75.81  E-value: 2.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQNIAPVFFREEYM----- 96
Cdd:PRK08260   17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGA-GRAFCAGADLSAGGNTFDLDAPRTPVEADEEDRadpsd 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622850714  97 ---------LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 162
Cdd:PRK08260   96 dgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVG 170
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
3-195 2.14e-15

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 75.27  E-value: 2.14e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   3 KHTDAAADvllekkgcagvITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV------I 76
Cdd:TIGR01929   8 KSTDGIAK-----------ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVrgdygyI 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  77 SEAEKAKQNIAPVffreeymlNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 156
Cdd:TIGR01929  77 DDSGVHRLNVLDV--------QRQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSY 148
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1622850714 157 LPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:TIGR01929 149 MARIVGqKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 188
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
7-186 2.30e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 75.03  E-value: 2.30e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   7 AAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEK----- 81
Cdd:PRK08252    1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGG-TFCAGMDLKAFARGERpsipg 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  82 ---AKQNIAPVffreeymlnnavgscQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLP 158
Cdd:PRK08252   80 rgfGGLTERPP---------------RKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGG---LL 141
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1622850714 159 RLQGKLGYFLA----LTGFRLKGRDVYRAGIA 186
Cdd:PRK08252  142 RLPRRIPYHIAmelaLTGDMLTAERAHELGLV 173
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
8-248 2.59e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 75.03  E-value: 2.59e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   8 AADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEaekaKQNIA 87
Cdd:PRK07511    2 SAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGG-FFCAGGNLNRLLE----NRAKP 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  88 PVFFREEY-MLNN---AVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR-LQG 162
Cdd:PRK07511   77 PSVQAASIdGLHDwirAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLPR 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 163 KLGYFLALTGFRLKGRDVYRAGIATHFVD-----SEKLAMLEEdlLALKSP-SKENIASVLENYHTESkidrdksfmLEE 236
Cdd:PRK07511  157 QLATELLLEGKPISAERLHALGVVNRLAEpgqalAEALALADQ--LAAGSPnALARIKSLIADAPEAT---------LAA 225
                         250
                  ....*....|..
gi 1622850714 237 HMDKINSCFSAN 248
Cdd:PRK07511  226 QLEAERDHFVAS 237
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
9-172 5.37e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 73.92  E-value: 5.37e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   9 ADVLLEKKGCAgVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKqniAP 88
Cdd:PRK06143    8 AGVTRDDRGVA-TLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQAS---AE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  89 VFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfPDVGGGYFLPRLQGKL-GYF 167
Cdd:PRK06143   84 AFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWArTRW 162

                  ....*
gi 1622850714 168 LALTG 172
Cdd:PRK06143  163 LLLTG 167
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
11-208 7.35e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 73.38  E-value: 7.35e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKK-GCAGViTLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDI-RVISEAEKAKQNIAP 88
Cdd:PRK07509    5 VSVTIEdGIADV-RLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGG-AFCAGLDVkSVASSPGNAVKLLFK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  89 vffREEYMLNNAvgscQK----------PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP 158
Cdd:PRK07509   83 ---RLPGNANLA----QRvslgwrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLR 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1622850714 159 RLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS---EKLAMLEEdlLALKSP 208
Cdd:PRK07509  156 GLVRKdVARELTYTARVFSAEEALELGLVTHVSDDplaAALALARE--IAQRSP 207
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
20-196 1.97e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 72.40  E-value: 1.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  20 GV--ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVFFREEYML 97
Cdd:PRK07468   14 GVatLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTADRATRIEEARRLAMM 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  98 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKG 177
Cdd:PRK07468   93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMSARLFDA 172
                         170
                  ....*....|....*....
gi 1622850714 178 RDVYRAGIATHFVDSEKLA 196
Cdd:PRK07468  173 EEAVRLGLLSRVVPAERLD 191
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
14-180 2.16e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 72.31  E-value: 2.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  14 EKKGCAGVITLNRPKFLNALTLNM---IRQIYSQLkkwEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVF 90
Cdd:PRK06142   11 ELADHVAQVTLNRPGKGNAMNPAFwseLPEIFRWL---DADPEVRAVVLSGSG-KHFSYGIDLPAMAGVFGQLGKDGLAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEY------MLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 162
Cdd:PRK06142   87 PRTDLrreilrLQAaiNAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIG 166
                         170       180
                  ....*....|....*....|
gi 1622850714 163 KlGYF--LALTgfrlkGRDV 180
Cdd:PRK06142  167 D-GHLreLALT-----GRDI 180
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
14-191 3.43e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 73.72  E-value: 3.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  14 EKKGCAGVITLNRPKF-LNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIsEAEKAKQNIAPVFFR 92
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMI-AACKTAQEVTQLSQE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  93 EEYMLNNAVGScQKPYVALIHGITMGGGVGLSVHGQFRVATE--KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LA 169
Cdd:TIGR02441  97 GQEMFERIEKS-QKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALdMM 175
                         170       180
                  ....*....|....*....|..
gi 1622850714 170 LTGFRLKGRDVYRAGIATHFVD 191
Cdd:TIGR02441 176 LTGKKIRADRAKKMGIVDQLVD 197
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
11-196 3.73e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 71.48  E-value: 3.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEqDPETFLIIIKGAgGKAFCAGGDI--RVISEAEKA------ 82
Cdd:PRK08140    6 ILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGA-GRGFCAGQDLadRDVTPGGAMpdlges 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  83 -KQNIAPvffreeymLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ 161
Cdd:PRK08140   84 iETFYNP--------LVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLV 155
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1622850714 162 GK---LGyfLALTGFRLKGRDVYRAGIATHFVDSEKLA 196
Cdd:PRK08140  156 GMaraLG--LALLGEKLSAEQAEQWGLIWRVVDDAALA 191
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
1-148 6.20e-14

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 71.13  E-value: 6.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHTDAAADVLLEKKGCAGVI--TLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVIse 78
Cdd:PRK08139    1 MMAPAAATEAPLLLREDRDGVAtlTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAA-GKAFCAGHDLKEM-- 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622850714  79 aeKAKQNIApvFFRE------EYMLnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF 148
Cdd:PRK08139   78 --RAARGLA--YFRAlfarcsRVMQ--AIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLF 147
PLN02888 PLN02888
enoyl-CoA hydratase
1-195 7.40e-14

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 70.55  E-value: 7.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHTDAAADVLLEK-KGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEA 79
Cdd:PLN02888    1 TMTQTVSENLILVPKsRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGS-GRAFCSGVDLTAAEEV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  80 EKAK---QNIAPVFFREEymlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF 156
Cdd:PLN02888   80 FKGDvkdVETDPVAQMER---------CRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQK 150
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1622850714 157 LPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:PLN02888  151 LSRIIGaNRAREVSLTAMPLTAETAERWGLVNHVVEESEL 190
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
11-203 9.36e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 70.15  E-value: 9.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKgAGGKAFCAGGDIRVISEAeKAKQNIAPVF 90
Cdd:PRK07260    4 IIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLIN-ANGKVFSVGGDLVEMKRA-VDEDDVQSLV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYM--LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYF 167
Cdd:PRK07260   82 KIAELVneISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGlNRATH 161
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1622850714 168 LALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLL 203
Cdd:PRK07260  162 LAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLL 197
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
12-196 1.04e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 70.38  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  12 LLEKKGCAGVITLNRPKFLNALTLnmirQIYSQLKKW----EQDPETFLIIIKGAGGkAFCAGGDIRVIseaekakqnIA 87
Cdd:PRK08258   20 LWEVDDGVATITLNRPERKNPLTF----ESYAELRDLfrelVYADDVKAVVLTGAGG-NFCSGGDVHEI---------IG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  88 PV----------FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF-PDVGGGYF 156
Cdd:PRK08258   86 PLtkmdmpellaFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACAL 165
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1622850714 157 LPRL--QGKLGYFLaLTGFRLKGRDVYRAGIATHFVDSEKLA 196
Cdd:PRK08258  166 LPRIigQGRASELL-YTGRSMSAEEGERWGFFNRLVEPEELL 206
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
11-190 1.64e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 69.66  E-value: 1.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLkkwEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKA-----KQN 85
Cdd:PRK08150    4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAF---ARLPEGVRAVVLHGEGDHFCAGLDLSELRERDAGegmhhSRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  86 IAPVFFREEYmlnnavgsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpdVGGG--YFLPRLQGK 163
Cdd:PRK08150   81 WHRVFDKIQY--------GRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIF--VGGGgsVRVPRLIGV 150
                         170       180
                  ....*....|....*....|....*...
gi 1622850714 164 LGYF-LALTGFRLKGRDVYRAGIATHFV 190
Cdd:PRK08150  151 ARMTdMMLTGRVYDAQEGERLGLAQYLV 178
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
13-162 3.98e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 68.41  E-value: 3.98e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  13 LEKKGCAGVITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNIAPVFFR 92
Cdd:PRK09076    7 LEIDGHVAILTLNNPP-ANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFG 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622850714  93 EEY-MLNNAVGscqkPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 162
Cdd:PRK09076   86 EAFeALSAFRG----VSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVG 152
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
5-229 6.89e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 67.78  E-value: 6.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   5 TDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAKQ 84
Cdd:PRK07827    2 TPVDTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGG-TFCAGADLSEAGGGGGDPY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  85 NIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL 164
Cdd:PRK07827   81 DAAVARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRA 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622850714 165 G--YFlaLTGFRLKGRDVYRAGIATHFVDS--EKLAMLEEDlLALKSP-----SKE-NIASVLENYhteskiDRD 229
Cdd:PRK07827  161 AarYY--LTGEKFGAAEAARIGLVTAAADDvdAAVAALLAD-LRRGSPqglaeSKAlTTAAVLAGF------DRD 226
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
1-228 2.14e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 66.35  E-value: 2.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHtdaaadVLLEKKGCAG---VITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAG---GDIR 74
Cdd:PRK06023    1 MTDH------ILVERPGAHPgvqVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEG-CFSAGndmQDFL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  75 VISEAEKAKQNIAPVFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGG 154
Cdd:PRK06023   74 AAAMGGTSFGSEILDFLI-------ALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSS 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 155 YFLPRLQGKLGYF--LALtGFRLKGRDVYRAGI-----ATHFVDSEKLAMLEEdlLALKSPSKENIASVLENYHTESKID 227
Cdd:PRK06023  147 LLAPRLMGHQRAFalLAL-GEGFSAEAAQEAGLiwkivDEEAVEAETLKAAEE--LAAKPPQALQIARDLMRGPREDILA 223

                  .
gi 1622850714 228 R 228
Cdd:PRK06023  224 R 224
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
1-195 1.17e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 64.47  E-value: 1.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHTDAAADVLLE--KKGCAgVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE 78
Cdd:PRK05864    1 VAGYRSTMSLVLVDhpRPEIA-LITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGA-GRGFSSGADHKSAGV 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  79 AEKAKQNIAPVF-FREEYMLNNAVGSCQK---PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF-PDVGG 153
Cdd:PRK05864   79 VPHVEGLTRPTYaLRSMELLDDVILALRRlhqPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGL 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1622850714 154 GYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:PRK05864  159 SYLLPRAIGSSRAFeIMLTGRDVDAEEAERIGLVSRQVPDEQL 201
PLN02921 PLN02921
naphthoate synthase
10-162 1.78e-11

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 64.42  E-value: 1.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  10 DVLLEK---KGCAGvITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQNI 86
Cdd:PLN02921   66 DIIYEKavgEGIAK-ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGKDGYVGPDD 144
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850714  87 APvffREEYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFpDVG-GGYFLPRLQG 162
Cdd:PLN02921  145 AG---RLNVLdLQIQIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVG 218
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
11-195 4.19e-11

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 62.83  E-value: 4.19e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDP-ETFLIIIKGAGgKAFCAG----------GDIRVISEA 79
Cdd:PRK05981    6 VTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAG-RGFCTGanlqgrgsggRESDSGGDA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  80 EKAKQNIAPVFFReeymlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPR 159
Cdd:PRK05981   85 GAALETAYHPFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPR 157
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1622850714 160 LQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:PRK05981  158 LVGKArAMELSLLGEKLPAETALQWGLVNRVVDDAEL 194
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
19-185 6.38e-11

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 63.76  E-value: 6.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  19 AGVITLNRP-KFLNALTLNMIRQIYSQLKKWEQDPEtfliiIKG---AGGKA--FCAGGDIRVISEAEKAKQniAPVFFR 92
Cdd:PRK11154   16 IAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKE-----LKGvvfISGKPdnFIAGADINMLAACKTAQE--AEALAR 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  93 EEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT--EKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLA 169
Cdd:PRK11154   89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGvSTALDMI 168
                         170
                  ....*....|....*.
gi 1622850714 170 LTGFRLKGRDVYRAGI 185
Cdd:PRK11154  169 LTGKQLRAKQALKLGL 184
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
20-222 6.77e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 61.97  E-value: 6.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  20 GVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK---AKQNIAPVFFReeym 96
Cdd:PRK11423   15 ATITFNNPAKRNALSKVLIDDLMQALSDLNRPEIRVVILRAPSGSKVWSAGHDIHELPSGGRdplSYDDPLRQILR---- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  97 lnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGgyfLPRLQGKLGYFLA----LTG 172
Cdd:PRK11423   91 ---MIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTNDAGFHIVkemfFTA 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622850714 173 FRLKGRDVYRAGIATHFVDSEKLAMLEEDL---LALKSP-----SKENIaSVLENYHT 222
Cdd:PRK11423  165 SPITAQRALAVGILNHVVEVEELEDFTLQMahhISEKAPlaiavIKEQL-RVLGEAHP 221
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
17-186 1.50e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 60.81  E-value: 1.50e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  17 GCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEqDPETFLIIIKGAGgKAFCAGGDIrviseaekAKQNIAPVFFREEYM 96
Cdd:PRK07854    8 GQVLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQG-TVFCAGADL--------SGDVYADDFPDALIE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  97 LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDvggGYFLPRLQGKLGYFLA----LTG 172
Cdd:PRK07854   78 MLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSLVGGGRAramlLGA 154
                         170
                  ....*....|....
gi 1622850714 173 FRLKGRDVYRAGIA 186
Cdd:PRK07854  155 EKLTAEQALATGMA 168
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
10-120 1.65e-10

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 61.06  E-value: 1.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  10 DVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV------ISEAEKAK 83
Cdd:PRK07396   14 DILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVrgyggyVDDDGVPR 93
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1622850714  84 QNIAPvffreeymLNNAVGSCQKPYVALIHGITMGGG 120
Cdd:PRK07396   94 LNVLD--------LQRLIRTCPKPVIAMVAGYAIGGG 122
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
24-208 2.74e-10

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 60.21  E-value: 2.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  24 LNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQNIAPVFFREEYMLNNAVGS 103
Cdd:PRK05674   21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGR-GRHFSAGADLAWMQQSADLDYNTNLDDARELAELMYNLYR 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 104 CQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRA 183
Cdd:PRK05674  100 LKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDGRRAREL 179
                         170       180
                  ....*....|....*....|....*...
gi 1622850714 184 G-IATHFVDSEKLAMLEE--DLLALKSP 208
Cdd:PRK05674  180 GlLAESYPAAELEAQVEAwiANLLLNSP 207
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-216 6.10e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 59.67  E-value: 6.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714   1 MSKHTDAAADVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISE-- 78
Cdd:PRK08272    2 RPVDLDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGA-GKGFCAGYDLSAYAEgs 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  79 -AEKAKQNIAPVFFREEY--------MLNNAVGS-----------CQKPYVALIHGITMGGGVGLSVHGQFRVATEkclf 138
Cdd:PRK08272   81 sSGGGGGAYPGKRQAVNHlpddpwdpMIDYQMMSrfvrgfmslwhAHKPTVAKVHGYCVAGGTDIALHCDQVIAAD---- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 139 ampETAIGLFPD-VGG----GYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLalkspskENI 213
Cdd:PRK08272  157 ---DAKIGYPPTrVWGvpatGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLV-------ERI 226

                  ...
gi 1622850714 214 ASV 216
Cdd:PRK08272  227 AAV 229
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
11-193 8.95e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 58.43  E-value: 8.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRVISEAEKAKQNIAPVF 90
Cdd:PRK06563    1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAH-GEHFTAGLDLADVAPKLAAGGFPFPEG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 FREEYMLnnaVG-SCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdVGGGYFlpRLQGKLGYFLA 169
Cdd:PRK06563   80 GIDPWGT---VGrRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILP-FGGATL--RFPQAAGWGNA 153
                         170       180
                  ....*....|....*....|....*...
gi 1622850714 170 ----LTGFRLKGRDVYRAGIATHFVDSE 193
Cdd:PRK06563  154 mrylLTGDEFDAQEALRLGLVQEVVPPG 181
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
21-160 1.24e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 58.06  E-value: 1.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  21 VITLNRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKgAGGKAFCAGGDIRVISEAEKAKQNIAPVffREEYMLNNA 100
Cdd:PRK07938   14 EVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLR-AEGRGFNAGVDIKELQATPGFTALIDAN--RGCFAAFRA 89
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 101 VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfpdVGGGYFLPRL 160
Cdd:PRK07938   90 VYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGA---LGAATHLQRL 146
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
22-195 2.83e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 57.34  E-value: 2.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAGGDIRVISEAEKAKQNIAPVfFREEYMLNNAV 101
Cdd:PRK07327   25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDFEVRARV-WREARDLVYNV 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 102 GSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGlfpdVGGG----YFLPRLQG--KLGYFLaLTGFRL 175
Cdd:PRK07327  103 INCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLG----VAAGdhaaIVWPLLCGmaKAKYYL-LLCEPV 177
                         170       180
                  ....*....|....*....|
gi 1622850714 176 KGRDVYRAGIATHFVDSEKL 195
Cdd:PRK07327  178 SGEEAERIGLVSLAVDDDEL 197
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
11-197 3.30e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 57.28  E-value: 3.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGGDIRviSEAEKAKQNIAPVF 90
Cdd:PRK08290    6 VRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGA-GKHFSAGHDLG--SGTPGRDRDPGPDQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 -------------------FREEYMLNNA--VGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLfp 149
Cdd:PRK08290   83 hptlwwdgatkpgveqryaREWEVYLGMCrrWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI-- 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622850714 150 dVGGGYFL------PRlqgKLGYFLaLTGFRLKGRDVYRAGIATHFV-----DSEKLAM 197
Cdd:PRK08290  161 -PGVEYFAhpwelgPR---KAKELL-FTGDRLTADEAHRLGMVNRVVprdelEAETLEL 214
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
11-195 1.75e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 54.96  E-value: 1.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGgKAFCAG----------GDIRVISEAE 80
Cdd:PRK12478    7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGydfgggfqhwGEAMMTDGRW 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  81 KAKQNIAPVFFRE-----EYMlnnAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAI-GLFPDvggG 154
Cdd:PRK12478   86 DPGKDFAMVTAREtgptqKFM---AIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLT---G 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1622850714 155 YFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 195
Cdd:PRK12478  160 MWLYRLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERL 200
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
11-162 1.07e-07

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 52.15  E-value: 1.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITL--NRPKfLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGaGGKAFCAGGDIRVISEAEKAKQNIAP 88
Cdd:PRK05869    8 VVSDGSQDAGLATLllSRPP-TNALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMPELRTLSAQEADTAA 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622850714  89 VFFREEYmlnNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 162
Cdd:PRK05869   86 RVRQQAV---DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
10-155 2.30e-07

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 51.74  E-value: 2.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  10 DVLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAG-----GKAFCAGGDIRV------ISE 78
Cdd:COG0447    19 DITYHRAEGIARIAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGpskdgGWAFCSGGDQRVrgrggyVYE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  79 AEKAKQNIAPVffreeYMLnnaVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAmpETAiglfPDVG---GGY 155
Cdd:COG0447    99 DGVGRLNILEV-----QRL---IRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFG--QTG----PDVGsfdAGY 164
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
11-162 1.39e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 49.12  E-value: 1.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  11 VLLEKKGCAGVITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAGGkAFCAGGDIRVISEAEKAkqniapvf 90
Cdd:PRK08259    5 VRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADLKAVGTGRGN-------- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  91 fREEYMLNNAVGSCQ----KPYVALIHGITMGGGVGLSVHGQFRVATEKCLFampetaiGLF------PDVGGGYF-LPR 159
Cdd:PRK08259   76 -RLHPSGDGPMGPSRmrlsKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVF-------GVFcrrwgvPLIDGGTVrLPR 147

                  ...
gi 1622850714 160 LQG 162
Cdd:PRK08259  148 LIG 150
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
107-162 1.44e-06

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 49.86  E-value: 1.44e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622850714 107 PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 162
Cdd:PRK11730  104 PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
22-190 1.79e-06

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 48.43  E-value: 1.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETFLIIIKGAgGKAFCAGG---DIRVISEAEKAkqniapvfFREEYMLN 98
Cdd:PRK07110   18 VTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGY-PNYFATGGtqeGLLSLQTGKGT--------FTEANLYS 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  99 NAVGsCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRlqgKLGYFLA----LTGFR 174
Cdd:PRK07110   89 LALN-CPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPE---KLGLALGqemlLTARY 164
                         170
                  ....*....|....*.
gi 1622850714 175 LKGRDVYRAGIATHFV 190
Cdd:PRK07110  165 YRGAELKKRGVPFPVL 180
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
22-214 2.68e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 41.98  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714  22 ITLNRPKFLNALTLNMIRQIYSQLKKWEQDPETflIIIKGAGgKAFCAGGDIRVISEAEKAKQNIApvfFREE--YMLNN 99
Cdd:PRK07112   17 LQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLP-EVFCFGADFSAIAEKPDAGRADL---IDAEplYDLWH 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622850714 100 AVGScqKPYVALIH--GITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPdvggGYFLPRLQGKLG----YFLALTGF 173
Cdd:PRK07112   91 RLAT--GPYVTIAHvrGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP----ACVLPFLIRRIGtqkaHYMTLMTQ 164
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1622850714 174 RLKGRDVYRAGIATHFV-DSEKLamLEEDLLALKSPSKENIA 214
Cdd:PRK07112  165 PVTAQQAFSWGLVDAYGaNSDTL--LRKHLLRLRCLNKAAVA 204
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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