NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1622849192|ref|XP_028686407|]
View 

inactive dipeptidyl peptidase 10 isoform X4 [Macaca mulatta]

Protein Classification

S9 family peptidase( domain architecture ID 12012129)

peptidase S9 family protein, an oligopeptidase which may cleave the prolyl bond of short peptides, similar to oligopeptidase B, which cleaves on the C-terminal side of lysyl and argininyl residues

CATH:  3.40.50.1820|2.140.10.30
EC:  3.4.-.-
Gene Ontology:  GO:0008236|GO:0006508
MEROPS:  S9
PubMed:  19508187|12369917|35631755
SCOP:  3000102

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 12-378 5.29e-141

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 415.56  E-value: 5.29e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192  12 SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEvedSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLR 91
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGE---GKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192  92 LTSSGkEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPT 170
Cdd:pfam00930  78 ITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 171 IKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACNKKYEMTSDTWLSKQ 250
Cdd:pfam00930 157 VELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELH 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 251 NEEPVFSRDGSKFFMTVPvKQGgrgeFHHIAMFLIQSKSeqitVRHLTSGNWEVIKILAYDETTHKIYFLSTESSPRGRQ 330
Cdd:pfam00930 236 QDPHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS----PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERH 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1622849192 331 LYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFCEGPRVP 378
Cdd:pfam00930 307 LYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
465-661 1.36e-48

Prolyl oligopeptidase family;


:

Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 169.72  E-value: 1.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 465 SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDE 544
Cdd:pfam00326   8 QLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 545 KLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNIHGLKEEN-ILIIHGTADTKVHFQHSAEL 617
Cdd:pfam00326  87 DLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVPPWQSLKL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1622849192 618 IKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 661
Cdd:pfam00326 167 VAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 12-378 5.29e-141

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 415.56  E-value: 5.29e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192  12 SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEvedSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLR 91
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGE---GKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192  92 LTSSGkEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPT 170
Cdd:pfam00930  78 ITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 171 IKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACNKKYEMTSDTWLSKQ 250
Cdd:pfam00930 157 VELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELH 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 251 NEEPVFSRDGSKFFMTVPvKQGgrgeFHHIAMFLIQSKSeqitVRHLTSGNWEVIKILAYDETTHKIYFLSTESSPRGRQ 330
Cdd:pfam00930 236 QDPHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS----PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERH 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1622849192 331 LYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFCEGPRVP 378
Cdd:pfam00930 307 LYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
465-661 1.36e-48

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 169.72  E-value: 1.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 465 SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDE 544
Cdd:pfam00326   8 QLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 545 KLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNIHGLKEEN-ILIIHGTADTKVHFQHSAEL 617
Cdd:pfam00326  87 DLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVPPWQSLKL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1622849192 618 IKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 661
Cdd:pfam00326 167 VAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
474-661 2.55e-41

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 150.17  E-value: 2.55e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 474 IVARFDGRGSGFQGlkilqeihRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVV 553
Cdd:COG1506    53 AVLAPDYRGYGESA--------GDWGGDEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 554 APITDLKLYA---SAFSERYLGMPSKEESTYQAASVLHNIHGLKEeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTM 630
Cdd:COG1506   125 AGVSDLRSYYgttREYTERLMGGPWEDPEAYAARSPLAYADKLKT-PLLLIHGEADDRVPPEQAERLYEALKKAGKPVEL 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1622849192 631 QVYPDEGHNVSEKSKYHLYSTILKFFSDCLK 661
Cdd:COG1506   204 LVYPGEGHGFSGAGAPDYLERILDFLDRHLK 234
PLN02442 PLN02442
S-formylglutathione hydrolase
 510-638 5.07e-04

S-formylglutathione hydrolase


Pssm-ID: 178061 [Multi-domain]  Cd Length: 283  Bit Score: 42.46  E-value: 5.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 510 VKFLLKL-----PYIDSKRLSIFGKGYGGYIASMI-LKSDEKlFKCGSVVAPI---TDLKLYASAFSErYLGmPSKEE-S 579
Cdd:PLN02442  126 VKELPKLlsdnfDQLDTSRASIFGHSMGGHGALTIyLKNPDK-YKSVSAFAPIanpINCPWGQKAFTN-YLG-SDKADwE 202

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 580 TYQAASVLHNIHGLKEEnILIIHGTADTKVHFQHSAELIKHLIK-AGVNYTMQVYPDEGH 638
Cdd:PLN02442  203 EYDATELVSKFNDVSAT-ILIDQGEADKFLKEQLLPENFEEACKeAGAPVTLRLQPGYDH 261
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 12-378 5.29e-141

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 415.56  E-value: 5.29e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192  12 SPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEvedSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLR 91
Cdd:pfam00930   1 SPDGKYLLLATNYTKNWRHSYTADYYIYDLETNRVEPLPPGE---GKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192  92 LTSSGkEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFT-GALYPKGKQYPYPKAGQVNPT 170
Cdd:pfam00930  78 ITSDG-SDGIFNGVADWVYEEEVLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTdEGPGPEVREIKYPKAGAPNPT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 171 IKLYVVNLYGPTHTlELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRPQNISILTVCETTTGACNKKYEMTSDTWLSKQ 250
Cdd:pfam00930 157 VELFVYDLASGKTV-EVVPPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELH 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 251 NEEPVFSRDGSKFFMTVPvKQGgrgeFHHIAMFLIQSKSeqitVRHLTSGNWEVIKILAYDETTHKIYFLSTESSPRGRQ 330
Cdd:pfam00930 236 QDPHFIKRDGSGFLWISE-RDG----YNHLYLYDLDGKS----PIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERH 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1622849192 331 LYSASTEGLLNRQCISCNFMKEqctYFDASFSPMNQHFLLFCEGPRVP 378
Cdd:pfam00930 307 LYSVSLDSGGEPTCLTDDSGDH---DYSASFSPNGSYYVLTYSGPDTP 351
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
465-661 1.36e-48

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 169.72  E-value: 1.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 465 SVLIDMDnVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDE 544
Cdd:pfam00326   8 QLLADRG-YVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 545 KLFKCGSVVAPITDLKLYAS----AFSERYLGMPS--KEESTYQAASVLHNIHGLKEEN-ILIIHGTADTKVHFQHSAEL 617
Cdd:pfam00326  87 DLFKAAVAHVPVVDWLAYMSdtslPFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYPpLLLIHGLLDDRVPPWQSLKL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1622849192 618 IKHLIKAGVNYTMQVYPDEGHNV-SEKSKYHLYSTILKFFSDCLK 661
Cdd:pfam00326 167 VAALQRKGVPFLLLIFPDEGHGIgKPRNKVEEYARELAFLLEYLG 211
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
474-661 2.55e-41

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 150.17  E-value: 2.55e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 474 IVARFDGRGSGFQGlkilqeihRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVV 553
Cdd:COG1506    53 AVLAPDYRGYGESA--------GDWGGDEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 554 APITDLKLYA---SAFSERYLGMPSKEESTYQAASVLHNIHGLKEeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTM 630
Cdd:COG1506   125 AGVSDLRSYYgttREYTERLMGGPWEDPEAYAARSPLAYADKLKT-PLLLIHGEADDRVPPEQAERLYEALKKAGKPVEL 203

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1622849192 631 QVYPDEGHNVSEKSKYHLYSTILKFFSDCLK 661
Cdd:COG1506   204 LVYPGEGHGFSGAGAPDYLERILDFLDRHLK 234
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 474-660 4.03e-09

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 58.00  E-value: 4.03e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 474 IVARFDGRGSGF-QGLkilqeiHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSDEKlFKCGSV 552
Cdd:COG1073    66 NVLAFDYRGYGEsEGE------PREEGSPERRDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPR-VKAVIL 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 553 VAPITDLK-----LYASAFSERYLGMPSKEESTY-----QAASVLHNIHGLKeENILIIHGTADTKVHFQHSAELIKhli 622
Cdd:COG1073   139 DSPFTSLEdlaaqRAKEARGAYLPGVPYLPNVRLasllnDEFDPLAKIEKIS-RPLLFIHGEKDEAVPFYMSEDLYE--- 214

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1622849192 623 KAGVNYTMQVYPDEGHNVSEKSKYHLY-STILKFFSDCL 660
Cdd:COG1073   215 AAAEPKELLIVPGAGHVDLYDRPEEEYfDKLAEFFKKNL 253
COG4099 COG4099
Predicted peptidase [General function prediction only];
420-640 2.99e-07

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 51.89  E-value: 2.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 420 DDYELPLQLSLPKDFMDRNQYALLLIM--------DEE-----PGGQLVTDKFRIDWDSVlidmdnVIVARFDgRGSGFQ 486
Cdd:COG4099    29 DGDTLPYRLYLPKGYDPGKKYPLVLFLhgagergtDNEkqlthGAPKFINPENQAKFPAI------VLAPQCP-EDDYWS 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 487 GLKILQEIHRrlgsvevkdqitAVKFLLKLPYIDSKRLSIFGKGYGGYIA-SMILKSDEkLFKCGSVVAPITDLklyasA 565
Cdd:COG4099   102 DTKALDAVLA------------LLDDLIAEYRIDPDRIYLTGLSMGGYGTwDLAARYPD-LFAAAVPICGGGDP-----A 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622849192 566 FSERYLGMPskeestyqaasvlhnihglkeenILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNV 640
Cdd:COG4099   164 NAANLKKVP-----------------------VWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVGHNS 215
YpfH COG0400
Predicted esterase [General function prediction only];
519-642 5.73e-05

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 44.51  E-value: 5.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 519 IDSKRLSIFGKGYGGYIASMILKSDEKLFKCgsVVApitdlklyasaFSerylGMPSKEESTYQAASVLHNIHglkeenI 598
Cdd:COG0400    86 IDPERIVLAGFSQGAAMALSLALRRPELLAG--VVA-----------LS----GYLPGEEALPAPEAALAGTP------V 142

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1622849192 599 LIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDeGHNVSE 642
Cdd:COG0400   143 FLAHGTQDPVIPVERAREAAEALEAAGADVTYREYPG-GHEISP 185
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
503-638 2.04e-04

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 43.42  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 503 VKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIAsMILKSDEKLFKCgsVVApitdlklyasafserYLGMPSKEESTYQ 582
Cdd:COG0412    90 AADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLA-LLAAARGPDLAA--AVS---------------FYGGLPADDLLDL 151

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622849192 583 AAsvlhNIHGlkeeNILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGH 638
Cdd:COG0412   152 AA----RIKA----PVLLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYPGAGH 199
PLN02442 PLN02442
S-formylglutathione hydrolase
 510-638 5.07e-04

S-formylglutathione hydrolase


Pssm-ID: 178061 [Multi-domain]  Cd Length: 283  Bit Score: 42.46  E-value: 5.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 510 VKFLLKL-----PYIDSKRLSIFGKGYGGYIASMI-LKSDEKlFKCGSVVAPI---TDLKLYASAFSErYLGmPSKEE-S 579
Cdd:PLN02442  126 VKELPKLlsdnfDQLDTSRASIFGHSMGGHGALTIyLKNPDK-YKSVSAFAPIanpINCPWGQKAFTN-YLG-SDKADwE 202

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 580 TYQAASVLHNIHGLKEEnILIIHGTADTKVHFQHSAELIKHLIK-AGVNYTMQVYPDEGH 638
Cdd:PLN02442  203 EYDATELVSKFNDVSAT-ILIDQGEADKFLKEQLLPENFEEACKeAGAPVTLRLQPGYDH 261
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
475-658 1.25e-03

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 40.76  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 475 VARFDGRGSGfqglkilqEIHRRLGSVE-----VKDQITAVKFLLKLPyidSKRLSIFGKGYGGYIASMILKSDEKLFKc 549
Cdd:COG2267    58 VLAFDLRGHG--------RSDGPRGHVDsfddyVDDLRAALDALRARP---GLPVVLLGHSMGGLIALLYAARYPDRVA- 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622849192 550 gSVVapitdlkLYASAFSERYLGMPSkeESTYQAASVLHNIHGLKEEnILIIHGTADTKVHFQHSAELIKHLIKAGvnyT 629
Cdd:COG2267   126 -GLV-------LLAPAYRADPLLGPS--ARWLRALRLAEALARIDVP-VLVLHGGADRVVPPEAARRLAARLSPDV---E 191

                         170       180       190
                  ....*....|....*....|....*....|
gi 1622849192 630 MQVYPDEGHNV-SEKSKYHLYSTILKFFSD 658
Cdd:COG2267   192 LVLLPGARHELlNEPAREEVLAAILAWLER 221
PRK11460 PRK11460
putative hydrolase; Provisional
 565-638 8.06e-03

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 38.48  E-value: 8.06e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622849192 565 AFSERYLGMPSKEestyQAASVLHnihglkeenilIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGH 638
Cdd:PRK11460  133 AFSGRYASLPETA----PTATTIH-----------LIHGGEDPVIDVAHAVAAQEALISLGGDVTLDIVEDLGH 191
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH