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Conserved domains on  [gi|1387223357|ref|XP_024835649|]
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XIAP-associated factor 1 isoform X4 [Bos taurus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
XAF1_C super family cl39927
XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino ...
 223-267 7.63e-14

XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino acids interferon (INF)-inducible pro-apoptotic protein. The XIAP binding region within XAF1, XIAP RING binding site, is located at the C-terminal portion of XAF1. This entry represents the C-terminal region which is functionally identified as XIAP RING-binding domain of XAF1.


The actual alignment was detected with superfamily member pfam18608:

Pssm-ID: 465820  Cd Length: 51  Bit Score: 64.83  E-value: 7.63e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1387223357 223 ASSPVEDETAYDILRRCSQCDILLPLPTLNHHQ-RCWFAQELQLNQ 267
Cdd:pfam18608   1 SPSALKDEAAYDILRRCSQCGILLPLPTLNQHQeKCLWLASLKGKQ 46
PLN03086 super family cl29366
PRLI-interacting factor K; Provisional
 4-99 3.32e-09

PRLI-interacting factor K; Provisional


The actual alignment was detected with superfamily member PLN03086:

Pssm-ID: 178635 [Multi-domain]  Cd Length: 567  Bit Score: 57.57  E-value: 3.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387223357   4 VLCPECKEPVLQHEMEEHCQGGHQQVGCAmCQQSVPKHSLESHEAQECQERPVECQFCQLAV-----------RLNKVDL 72
Cdd:PLN03086  454 VHCEKCGQAFQQGEMEKHMKVFHEPLQCP-CGVVLEKEQMVQHQASTCPLRLITCRFCGDMVqaggsamdvrdRLRGMSE 532

                          90       100
                  ....*....|....*....|....*..
gi 1387223357  73 HEHHCGQQTELCPDCGQHVMLRVLARH 99
Cdd:PLN03086  533 HESICGSRTAPCDSCGRSVMLKEMDIH 559
 
Name Accession Description Interval E-value
XAF1_C pfam18608
XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino ...
 223-267 7.63e-14

XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino acids interferon (INF)-inducible pro-apoptotic protein. The XIAP binding region within XAF1, XIAP RING binding site, is located at the C-terminal portion of XAF1. This entry represents the C-terminal region which is functionally identified as XIAP RING-binding domain of XAF1.


Pssm-ID: 465820  Cd Length: 51  Bit Score: 64.83  E-value: 7.63e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1387223357 223 ASSPVEDETAYDILRRCSQCDILLPLPTLNHHQ-RCWFAQELQLNQ 267
Cdd:pfam18608   1 SPSALKDEAAYDILRRCSQCGILLPLPTLNQHQeKCLWLASLKGKQ 46
PLN03086 PLN03086
PRLI-interacting factor K; Provisional
 4-99 3.32e-09

PRLI-interacting factor K; Provisional


Pssm-ID: 178635 [Multi-domain]  Cd Length: 567  Bit Score: 57.57  E-value: 3.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387223357   4 VLCPECKEPVLQHEMEEHCQGGHQQVGCAmCQQSVPKHSLESHEAQECQERPVECQFCQLAV-----------RLNKVDL 72
Cdd:PLN03086  454 VHCEKCGQAFQQGEMEKHMKVFHEPLQCP-CGVVLEKEQMVQHQASTCPLRLITCRFCGDMVqaggsamdvrdRLRGMSE 532

                          90       100
                  ....*....|....*....|....*..
gi 1387223357  73 HEHHCGQQTELCPDCGQHVMLRVLARH 99
Cdd:PLN03086  533 HESICGSRTAPCDSCGRSVMLKEMDIH 559
 
Name Accession Description Interval E-value
XAF1_C pfam18608
XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino ...
 223-267 7.63e-14

XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino acids interferon (INF)-inducible pro-apoptotic protein. The XIAP binding region within XAF1, XIAP RING binding site, is located at the C-terminal portion of XAF1. This entry represents the C-terminal region which is functionally identified as XIAP RING-binding domain of XAF1.


Pssm-ID: 465820  Cd Length: 51  Bit Score: 64.83  E-value: 7.63e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1387223357 223 ASSPVEDETAYDILRRCSQCDILLPLPTLNHHQ-RCWFAQELQLNQ 267
Cdd:pfam18608   1 SPSALKDEAAYDILRRCSQCGILLPLPTLNQHQeKCLWLASLKGKQ 46
PLN03086 PLN03086
PRLI-interacting factor K; Provisional
 4-99 3.32e-09

PRLI-interacting factor K; Provisional


Pssm-ID: 178635 [Multi-domain]  Cd Length: 567  Bit Score: 57.57  E-value: 3.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387223357   4 VLCPECKEPVLQHEMEEHCQGGHQQVGCAmCQQSVPKHSLESHEAQECQERPVECQFCQLAV-----------RLNKVDL 72
Cdd:PLN03086  454 VHCEKCGQAFQQGEMEKHMKVFHEPLQCP-CGVVLEKEQMVQHQASTCPLRLITCRFCGDMVqaggsamdvrdRLRGMSE 532

                          90       100
                  ....*....|....*....|....*..
gi 1387223357  73 HEHHCGQQTELCPDCGQHVMLRVLARH 99
Cdd:PLN03086  533 HESICGSRTAPCDSCGRSVMLKEMDIH 559
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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