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Conserved domains on  [gi|1370478878|ref|XP_024308883|]
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ciliary rootlet coiled-coil protein 2 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 401-959 8.99e-28

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 122.35  E-value: 8.99e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELwaaqKLQQERAREQAREREALRGQLEAQRLEVQQCR 480
Cdd:COG1196    212 AERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL----EELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  481 ASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKV 560
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  561 SGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSAL 640
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 NHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQAcgrLEQRQEQLEGQAALLGREKAQLQEQ 720
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  721 VGQVTCQKQALEEQLAqslqdqEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRvERDSLESSLLE 800
Cdd:COG1196    525 AVAVLIGVEAAYEAAL------EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA-ALAAALARGAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  801 AQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQL 880
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  881 QREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEEL 959
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 926-1534 1.43e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 1.43e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  926 LKQERDESLLQLEHkMQQALS-----LKETERSLlsEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFED 1000
Cdd:COG1196    170 YKERKEEAERKLEA-TEENLErlediLGELERQL--EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1001 AITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKD 1080
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1081 VLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLK 1160
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1161 AENQRRSGEAHELQaqcsQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAE 1240
Cdd:COG1196    407 EAEEALLERLERLE----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1241 LHSVTRKLQEAS-----------GVADALQARLDQACHRIHSLEQELAQAEGARQDAEAqlGRLCSTLRRGLGLQRQSPW 1309
Cdd:COG1196    483 LEELAEAAARLLllleaeadyegFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE--AALAAALQNIVVEDDEVAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1310 ASPEQPGSPTKGSDSSQALPGQQGTSPPARPHSPLRwpsptpGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQM 1389
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA------IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1390 ATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAgQEKRRLQEQ 1469
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE-EERELAEAE 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1470 LETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHrcQKAEVSLEPLRQMEQETLKRE-----EDVARLGA 1534
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEEL--LEEEALEELPEPPDLEELERElerleREIEALGP 781
Rootletin super family cl23727
Ciliary rootlet component, centrosome cohesion;
127-263 2.53e-12

Ciliary rootlet component, centrosome cohesion;


The actual alignment was detected with superfamily member pfam15035:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 67.37  E-value: 2.53e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  127 QLQARLETTEAQLRRSELEHSVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGEL 206
Cdd:pfam15035   50 ELLLRKLTLEPRLQRLEREHSADLEEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREEL 129

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878  207 ELR--RWAQRQTRSGGL--GQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTA 263
Cdd:pfam15035  130 EQKesEWRKEEEAFNEYlsSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1450-1639 4.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1450 LEHLASVRAAGQEKRRLQEQLETLRQALEESRRHsQGLAKQGKLLEEQLTNLEHRCQKAEVSL--EPLRQMEQETLKREE 1527
Cdd:COG4913    231 VEHFDDLERAHEALEDAREQIELLEPIRELAERY-AAARERLAELEYLRAALRLWFAQRRLELleAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1528 DVARLGAEKEQLDQSLNSLHQEVDGA-LRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRdlateAERLHGARPQATQALES 1606
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEAL-----LAALGLPLPASAEEFAA 384

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1370478878 1607 QEWTHQQQVKVLEEQVASLKEQLDQEVQWRQQA 1639
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAALRDL 417
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 401-959 8.99e-28

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 122.35  E-value: 8.99e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELwaaqKLQQERAREQAREREALRGQLEAQRLEVQQCR 480
Cdd:COG1196    212 AERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL----EELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  481 ASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKV 560
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  561 SGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSAL 640
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 NHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQAcgrLEQRQEQLEGQAALLGREKAQLQEQ 720
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  721 VGQVTCQKQALEEQLAqslqdqEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRvERDSLESSLLE 800
Cdd:COG1196    525 AVAVLIGVEAAYEAAL------EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA-ALAAALARGAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  801 AQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQL 880
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  881 QREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEEL 959
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 523-1290 8.91e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 109.76  E-value: 8.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  523 RSLLLQAERREE-LALRRERSCRALETSQGRLQQLEEKVSGLREELASVrealstaqlqrdvvESEREGLRSALARAECS 601
Cdd:TIGR02168  203 KSLERQAEKAERyKELKAELRELELALLVLRLEELREELEELQEELKEA--------------EEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  602 NADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQlal 681
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  682 eraerrglqqacgrLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQ---LAQSLQDQEAQMGTLQQALQGKDA 758
Cdd:TIGR02168  346 --------------LEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  759 LSEERAQLLAKQEALERqgRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSdwe 838
Cdd:TIGR02168  412 LEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  839 vqemklrqdtvrlqrqvAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREA 918
Cdd:TIGR02168  487 -----------------LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  919 L--------KGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQ--------A 982
Cdd:TIGR02168  550 VvvenlnaaKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvvD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  983 TISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAE--RLRAQLTVAQEGLAALRQELQGVEESREG 1060
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1061 LHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQ 1140
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1141 AGGDARQELRELHRQVRTLKAENQRRSGEAHELQ---AQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGE 1217
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRerlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370478878 1218 AHGQRLQEHLRESRGAEQ---TLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQL 1290
Cdd:TIGR02168  870 ELESELEALLNERASLEEalaLLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 926-1534 1.43e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 1.43e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  926 LKQERDESLLQLEHkMQQALS-----LKETERSLlsEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFED 1000
Cdd:COG1196    170 YKERKEEAERKLEA-TEENLErlediLGELERQL--EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1001 AITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKD 1080
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1081 VLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLK 1160
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1161 AENQRRSGEAHELQaqcsQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAE 1240
Cdd:COG1196    407 EAEEALLERLERLE----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1241 LHSVTRKLQEAS-----------GVADALQARLDQACHRIHSLEQELAQAEGARQDAEAqlGRLCSTLRRGLGLQRQSPW 1309
Cdd:COG1196    483 LEELAEAAARLLllleaeadyegFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE--AALAAALQNIVVEDDEVAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1310 ASPEQPGSPTKGSDSSQALPGQQGTSPPARPHSPLRwpsptpGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQM 1389
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA------IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1390 ATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAgQEKRRLQEQ 1469
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE-EERELAEAE 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1470 LETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHrcQKAEVSLEPLRQMEQETLKRE-----EDVARLGA 1534
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEEL--LEEEALEELPEPPDLEELERElerleREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 646-1419 1.07e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERrglqqacGRLEQRQEQLEGQAALLGREKAQLQEQvgqvt 725
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV-------SELEEEIEELQKELYALANEISRLEQQ----- 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  726 cqKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALErqgrlaaEEAADLRVERDSLESSLLEAQQLA 805
Cdd:TIGR02168  304 --KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK-------EELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  806 TKLQEQLEEEARsaglARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKE 885
Cdd:TIGR02168  375 EELEEQLETLRS----KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  886 TLsltlAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDesllQLEHKMQQALSLKETERSLLSEELSRArrt 965
Cdd:TIGR02168  451 EL----QEELERLEEALEELREELEEAEQALDAAERELAQLQARLD----SLERLQENLEGFSEGVKALLKNQSGLS--- 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  966 lervqqeaqsqqeqaqaTISATTEELKALQAQFEDAITAhqrettALRESLQDLAAERGDVEREAERLRAQLTVAQEGLA 1045
Cdd:TIGR02168  520 -----------------GILGVLSELISVDEGYEAAIEA------ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFL 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1046 ALRQELQGVEESREGLHREAQEARRALSDEAREKDVLL---------------------------------------LFN 1086
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddldnalelakklrpgyrivtldgdLVR 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1087 SELRATICRAEQEKASFKRSKE--EKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQ 1164
Cdd:TIGR02168  657 PGGVITGGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1165 RRSGEAH---ELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQ---EHLRESRGAEQTLR 1238
Cdd:TIGR02168  737 RLEAEVEqleERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKalrEALDELRAELTLLN 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1239 AELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLqrqspwaspeqpgsp 1318
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE--------------- 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1319 tkgsdssqalpgqqgtspparphsplrwpsptpggRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSE 1398
Cdd:TIGR02168  882 -----------------------------------RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820
                   ....*....|....*....|.
gi 1370478878 1399 AECRCARAQSRVGQLQKALAE 1419
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSE 947
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
487-1067 3.39e-16

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 84.71  E-value: 3.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  487 GREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERscraLETSQGRLQQLEEKVSGLREE 566
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDLRETIAETERE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  567 LASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQ 646
Cdd:PRK02224   274 REELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  647 LEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTC 726
Cdd:PRK02224   354 LEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  727 QKQALEEQLAQSLQDQEA-QMGTLQQALQGK---DALSEERAQLlakqEALErqgrlaaEEAADLRVERDSLESSLLEAQ 802
Cdd:PRK02224   434 TLRTARERVEEAEALLEAgKCPECGQPVEGSphvETIEEDRERV----EELE-------AELEDLEEEVEEVEERLERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  803 QLAtKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEmKLRQDTVRLQRQvAQQEREAQRALESQALAHREALAQLQR 882
Cdd:PRK02224   503 DLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAE-ELRERAAELEAE-AEEKREAAAEAEEEAEEAREEVAELNS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  883 EKETLSLTLaeekevarcqleQEKELVTKSAAEREALKGEIQSLkQERDESLLQLEHKMQQALSLKETERSLLSEELSRA 962
Cdd:PRK02224   580 KLAELKERI------------ESLERIRTLLAAIADAEDEIERL-REKREALAELNDERRERLAEKRERKRELEAEFDEA 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  963 RrtlervqqeaqsqqeqaqatisatTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRaqltvaqe 1042
Cdd:PRK02224   647 R------------------------IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE-------- 694

                          570       580
                   ....*....|....*....|....*...
gi 1370478878 1043 glaALRQELQGVEESR---EGLHREAQE 1067
Cdd:PRK02224   695 ---ELRERREALENRVealEALYDEAEE 719
PTZ00121 PTZ00121
MAEBL; Provisional
 903-1637 8.05e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 8.05e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  903 EQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSR---ARRTLE-RVQQEAQSQQE 978
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKaeeARKAEDaKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  979 QAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAqltvAQEGLAAlrQELQGVEESR 1058
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK----AEDAKKA--EAVKKAEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1059 eglhREAQEARRA----LSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAh 1134
Cdd:PTZ00121  1237 ----KDAEEAKKAeeerNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKA- 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1135 lwELEQAGGDARQELRELHRQVRTLK--AENQRRSGEAHELQAQCSQEVLELRRQAAKA-EAKHEGARKEVLGLQRKLAE 1211
Cdd:PTZ00121  1312 --EEAKKADEAKKKAEEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaEKKKEEAKKKADAAKKKAEE 1389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1212 VEAAGEAHgQRLQEHLRES----RGAEQTLRAElhsVTRKLQEASGVADALQARLDQA--CHRIHSLEQELAQAEGARQD 1285
Cdd:PTZ00121  1390 KKKADEAK-KKAEEDKKKAdelkKAAAAKKKAD---EAKKKAEEKKKADEAKKKAEEAkkADEAKKKAEEAKKAEEAKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1286 AEAQlgRLCSTLRRGLGLQRQSPWASPEQPGSPTKGSDSSQALPGQQgTSPPARPHSPLRWPSPTPGGRSSELMDVATVQ 1365
Cdd:PTZ00121  1466 AEEA--KKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK-KADEAKKAEEAKKADEAKKAEEAKKADEAKKA 1542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1366 DILRDfVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKAlaeaeegqrRVEGALSSARAARALQKEAL 1445
Cdd:PTZ00121  1543 EEKKK-ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEA 1612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1446 RRLELEHLASVRAAGQEKRRlqEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQMEQETLKR 1525
Cdd:PTZ00121  1613 KKAEEAKIKAEELKKAEEEK--KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1526 EEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQrlqdltAQHQRDLATEAERLHGARPQATQALE 1605
Cdd:PTZ00121  1691 AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE------AEEDKKKAEEAKKDEEEKKKIAHLKK 1764

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1370478878 1606 SQEWTHQQQVKvleEQVASLKEQLDQEVQWRQ 1637
Cdd:PTZ00121  1765 EEEKKAEEIRK---EKEAVIEEELDEEDEKRR 1793
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
127-263 2.53e-12

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 67.37  E-value: 2.53e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  127 QLQARLETTEAQLRRSELEHSVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGEL 206
Cdd:pfam15035   50 ELLLRKLTLEPRLQRLEREHSADLEEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREEL 129

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878  207 ELR--RWAQRQTRSGGL--GQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTA 263
Cdd:pfam15035  130 EQKesEWRKEEEAFNEYlsSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 676-1377 4.47e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 4.47e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  676 EQQLALERAERRG-----LQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQ 750
Cdd:pfam15921  244 EDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  751 QAL-QGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLesslleaQQLATKLQEQLEEEARSAGLARQALQVE 829
Cdd:pfam15921  324 STVsQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF-------SQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  830 MEQLQSDWEvQEMKLRQDTVRLQRQVAQQEREAQRAlesqalahrealaqlqrekETLSLTLAEEkevarCQLEQEKELV 909
Cdd:pfam15921  397 KEQNKRLWD-RDTGNSITIDHLRRELDDRNMEVQRL-------------------EALLKAMKSE-----CQGQMERQMA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  910 tksaaereALKGeiqslkqeRDESLLQLEHKMQQALSLKETERSLLsEELSRARRTLErvqqeaqsqqeQAQATISATTE 989
Cdd:pfam15921  452 --------AIQG--------KNESLEKVSSLTAQLESTKEMLRKVV-EELTAKKMTLE-----------SSERTVSDLTA 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  990 ELKalqaQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAqltvAQEGLAALRQELQGVEESREGLHREAQEAR 1069
Cdd:pfam15921  504 SLQ----EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRN----VQTECEALKLQMAEKDKVIEILRQQIENMT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1070 RALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQEL 1149
Cdd:pfam15921  576 QLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQER 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1150 RELHRQVRTLKAE-------------NQRRSGEAHE-------LQAQCSQEVLELRRQAAKAEAKHEG-ARKEVLGLQRK 1208
Cdd:pfam15921  656 DQLLNEVKTSRNElnslsedyevlkrNFRNKSEEMEtttnklkMQLKSAQSELEQTRNTLKSMEGSDGhAMKVAMGMQKQ 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1209 LAEVEA---AGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQD 1285
Cdd:pfam15921  736 ITAKRGqidALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1286 AEAQLGRLCSTLRRG------LGLQRQSPWASPEQPGSPTKGSDSSQALPgqqgTSPPARPHSPLRWPSPTPGGRSSELM 1359
Cdd:pfam15921  816 ASLQFAECQDIIQRQeqesvrLKLQHTLDVKELQGPGYTSNSSMKPRLLQ----PASFTRTHSNVPSSQSTASFLSHHSR 891

                          730
                   ....*....|....*....
gi 1370478878 1360 DVATV-QDILRDFVQKLRE 1377
Cdd:pfam15921  892 KTNALkEDPTRDLKQLLQE 910
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 516-1292 5.22e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.93  E-value: 5.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  516 AEAAELQRSLLLQAERREELALRRErscraletsqgrlqQLEEKVSGLREELASVREALSTAQLQRDVVESER------- 588
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDD--------------QWKEKRDELNGELSAADAAVAKDRSELEALEDQHgafldad 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  589 -EGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDksalnhLALQLEQERDQLREQRKTLEQERAR 667
Cdd:pfam12128  339 iETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQ------NNRDIAGIKDKLAKIREARDRQLAV 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  668 AGEQLAQAEQQLaleraeRRGLQQACGRLEQRQEQLEGQAallgrekAQLQEQVGQVTCQKQALeEQLAQSLQDQEAQMG 747
Cdd:pfam12128  413 AEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRL-------GELKLRLNQATATPELL-LQLENFDERIERARE 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  748 TLQQALQGKDALSEERAQL------------LAKQEALERQGRLAAEEA----------ADLRVE----RDSLESSLLEA 801
Cdd:pfam12128  479 EQEAANAEVERLQSELRQArkrrdqasealrQASRRLEERQSALDELELqlfpqagtllHFLRKEapdwEQSIGKVISPE 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  802 QQLATKLQEQLEEEARSAGLARQALQVEMEQLQ-SDWEVQEMKLRQDTVRLQRQVaQQEREAQRALESQALAHREALAQL 880
Cdd:pfam12128  559 LLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDvPEWAASEEELRERLDKAEEAL-QSAREKQAAAEEQLVQANGELEKA 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  881 QREkETLSLTLAEEKEVARCQL----EQEKELVTKSAAEREALKGE-IQSLKQErdesLLQLEHKMQQALSLKETERSLL 955
Cdd:pfam12128  638 SRE-ETFARTALKNARLDLRRLfdekQSEKDKKNKALAERKDSANErLNSLEAQ----LKQLDKKHQAWLEEQKEQKREA 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  956 SEELSRARRTLErvqqeaqsqqeqaqatiSATTEELKALQAQFEDAITAHQRETTALreslqdlaaergdvEREAERLRA 1035
Cdd:pfam12128  713 RTEKQAYWQVVE-----------------GALDAQLALLKAAIAARRSGAKAELKAL--------------ETWYKRDLA 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1036 QLTVAQEGLAALRQELQGVEESREGLHREAQEARRalsdearekdvlllFNSELRATIcraEQEKASFKRSKEEKEQKLL 1115
Cdd:pfam12128  762 SLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLR--------------YFDWYQETW---LQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1116 ILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLkaenQRRSGEAHELQ--AQCSQEVLELRRQAAKAEA 1193
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE----MSKLATLKEDAnsEQAQGSIGERLAQLEDLKL 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1194 KHEGARKEVLGLQRKLAEVEAAGEAHGqrLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLE 1273
Cdd:pfam12128  901 KRDYLSESVKKYVEHFKNVIADHSGSG--LAETWESLREEDHYQNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLREQV 978

                          810
                   ....*....|....*....
gi 1370478878 1274 QELAQAEGARQDAEAQLGR 1292
Cdd:pfam12128  979 SILGVDLTEFYDVLADFDR 997
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1450-1639 4.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1450 LEHLASVRAAGQEKRRLQEQLETLRQALEESRRHsQGLAKQGKLLEEQLTNLEHRCQKAEVSL--EPLRQMEQETLKREE 1527
Cdd:COG4913    231 VEHFDDLERAHEALEDAREQIELLEPIRELAERY-AAARERLAELEYLRAALRLWFAQRRLELleAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1528 DVARLGAEKEQLDQSLNSLHQEVDGA-LRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRdlateAERLHGARPQATQALES 1606
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEAL-----LAALGLPLPASAEEFAA 384

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1370478878 1607 QEWTHQQQVKVLEEQVASLKEQLDQEVQWRQQA 1639
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAALRDL 417
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 577-828 7.28e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 7.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  577 AQLQRDVVESEREGLRSALA--RAECSNADLEllvrRLKSEGVEQRDSLA----AMAALMEGLAQDKSALNHLALQLEQE 650
Cdd:NF012221  1567 AEADRQRLEQEKQQQLAAISgsQSQLESTDQN----ALETNGQAQRDAILeesrAVTKELTTLAQGLDALDSQATYAGES 1642

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  651 RDQLREQ---------RKTLEQERARAGEQLAQAEQQL---------ALERAERrGLQQA---CGRLEQRQEQLEGQA-- 707
Cdd:NF012221  1643 GDQWRNPfagglldrvQEQLDDAKKISGKQLADAKQRHvdnqqkvkdAVAKSEA-GVAQGeqnQANAEQDIDDAKADAek 1721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  708 ----ALLGREKAQLQEQVGQVTCQKqaleeqlAQSLQDQEAQMGTLQQALQGKDALSeeraqllAKQEALER------QG 777
Cdd:NF012221  1722 rkddALAKQNEAQQAESDANAAAND-------AQSRGEQDASAAENKANQAQADAKG-------AKQDESDKpnrqgaAG 1787

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370478878  778 RLAAEEAADLRVERDSLESSLLEAQ-----QLATKLQEQLEEEARSAGLARQALQV 828
Cdd:NF012221  1788 SGLSGKAYSVEGVAEPGSHINPDSPaaadgRFSEGLTEQEQEALEGATNAVNRLQI 1843
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 690-781 7.88e-03

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 39.88  E-value: 7.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  690 QQACGRLEQRQEQLEGQAALLGREkaQLQEQVGQVTCQKQALEEQlaQSLQDQEAQmgtLQQALQGKDALSEERAQLLAK 769
Cdd:NF038305   115 QQAGQQETQLQQQLNQLQAQTSPQ--QLNQLLKSEQKQGQALASG--QLPEEQKEQ---LQQFKSNPQALDKFLAQQLTQ 187

                           90
                   ....*....|....*.
gi 1370478878  770 ----QEALERQGRLAA 781
Cdd:NF038305   188 irtqAEEAEKQARLEA 203
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 401-959 8.99e-28

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 122.35  E-value: 8.99e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELwaaqKLQQERAREQAREREALRGQLEAQRLEVQQCR 480
Cdd:COG1196    212 AERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL----EELEAELAELEAELEELRLELEELELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  481 ASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKV 560
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  561 SGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSAL 640
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 NHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQAcgrLEQRQEQLEGQAALLGREKAQLQEQ 720
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  721 VGQVTCQKQALEEQLAqslqdqEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRvERDSLESSLLE 800
Cdd:COG1196    525 AVAVLIGVEAAYEAAL------EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA-ALAAALARGAI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  801 AQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQL 880
Cdd:COG1196    598 GAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA 677

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  881 QREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEEL 959
Cdd:COG1196    678 EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 433-1034 6.31e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 113.11  E-value: 6.31e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  433 LQEQLSESRRELWAAQ-KLQQERAREQAREREALRGQLEAQRLEVQQCRAsckllgrEKAALEMVVEELKGKADAADAEK 511
Cdd:COG1196    218 LKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEA-------ELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  512 QGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGL 591
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  592 RSALARAEcsnadlellvrrlKSEGVEQRDSLAAMAALMEGLAQDKSALNHLAlQLEQERDQLREQRKTLEQERARAGEQ 671
Cdd:COG1196    371 EAELAEAE-------------EELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEALAELEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  672 LAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQslQDQEAQMGTLQQ 751
Cdd:COG1196    437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD--YEGFLEGVKAAL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  752 ALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATK--------LQEQLEEEARSAGLAR 823
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKagratflpLDKIRARAALAAALAR 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  824 QALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLE 903
Cdd:COG1196    595 GAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  904 QEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQAT 983
Cdd:COG1196    675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878  984 ISATTEELKALQAQFEDAITAHQR----------ETTALRESLQDLAAERGDVEREAERLR 1034
Cdd:COG1196    755 ELPEPPDLEELERELERLEREIEAlgpvnllaieEYEELEERYDFLSEQREDLEEARETLE 815
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 523-1290 8.91e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 109.76  E-value: 8.91e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  523 RSLLLQAERREE-LALRRERSCRALETSQGRLQQLEEKVSGLREELASVrealstaqlqrdvvESEREGLRSALARAECS 601
Cdd:TIGR02168  203 KSLERQAEKAERyKELKAELRELELALLVLRLEELREELEELQEELKEA--------------EEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  602 NADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQlal 681
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  682 eraerrglqqacgrLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQ---LAQSLQDQEAQMGTLQQALQGKDA 758
Cdd:TIGR02168  346 --------------LEELKEELESLEAELEELEAELEELESRLEELEEQLETLrskVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  759 LSEERAQLLAKQEALERqgRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSdwe 838
Cdd:TIGR02168  412 LEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  839 vqemklrqdtvrlqrqvAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREA 918
Cdd:TIGR02168  487 -----------------LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  919 L--------KGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQ--------A 982
Cdd:TIGR02168  550 VvvenlnaaKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvvD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  983 TISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAE--RLRAQLTVAQEGLAALRQELQGVEESREG 1060
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1061 LHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQ 1140
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1141 AGGDARQELRELHRQVRTLKAENQRRSGEAHELQ---AQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGE 1217
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRerlESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370478878 1218 AHGQRLQEHLRESRGAEQ---TLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQL 1290
Cdd:TIGR02168  870 ELESELEALLNERASLEEalaLLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 406-1156 1.56e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.56e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  406 RAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKlQQERAREQAREREALRGQLEAQRLEVQQcrasckl 485
Cdd:TIGR02168  210 EKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEE-ELEELTAELQELEEKLEELRLEVSELEE------- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  486 lgrEKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLRE 565
Cdd:TIGR02168  282 ---EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  566 ELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLAL 645
Cdd:TIGR02168  359 ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 Q-----LEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEG---QAALLGREKAQL 717
Cdd:TIGR02168  439 QaeleeLEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfseGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  718 QEQVGQVTCQ-------KQALEEQLAQSLQDqeAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVE 790
Cdd:TIGR02168  519 SGILGVLSELisvdegyEAAIEAALGGRLQA--VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  791 RDSLESSLLEAQQLATKLQEQLE----------------EEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQ 854
Cdd:TIGR02168  597 IEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  855 V----AQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQER 930
Cdd:TIGR02168  677 ReieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  931 DESLLQLEhkmqqALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDA---ITAHQR 1007
Cdd:TIGR02168  757 TELEAEIE-----ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLrerLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1008 ETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNS 1087
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRS 911

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1088 ELRATICRAEQEKASFKRSKEEKEQKLL-ILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQV 1156
Cdd:TIGR02168  912 ELRRELEELREKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 415-1229 2.30e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.22  E-value: 2.30e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  415 REQELCLQLKSSQALVASLQEQLSESRREL--WAAQKLQQERAREQAREREALRGQLEAQRLEVQQcrasckllgREKAA 492
Cdd:TIGR02168  173 RRKETERKLERTRENLDRLEDILNELERQLksLERQAEKAERYKELKAELRELELALLVLRLEELR---------EELEE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  493 LEMVVEELKGKADAADAEKQGLEAEAAELqRSLLLQAERREELAlrrerscraletsQGRLQQLEEKVSGLREELASVRE 572
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEEL-RLEVSELEEEIEEL-------------QKELYALANEISRLEQQKQILRE 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  573 ALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERD 652
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  653 QLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQAcgRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALE 732
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK--LEEAELKELQAELEELEEELEELQEELERLEEALEELR 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  733 EQLAQSLQDQEAQMGTLQQALQGKDAL----------SEERAQLLAKQEALERQGRLAAE--------EAADLRVERDSL 794
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSLerlqenlegfSEGVKALLKNQSGLSGILGVLSElisvdegyEAAIEAALGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  795 ESSLLEAQQLATKLQEQLeEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESqALAH- 873
Cdd:TIGR02168  548 QAVVVENLNAAKKAIAFL-KQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY-LLGGv 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  874 ------REALAQLQREKETLSLTLAEEKEVARCQleqekeLVTKSAAEREAL----KGEIQSLKQERDEsLLQLEHKMQQ 943
Cdd:TIGR02168  626 lvvddlDNALELAKKLRPGYRIVTLDGDLVRPGG------VITGGSAKTNSSilerRREIEELEEKIEE-LEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  944 ALSLKETERSLLSEELSRARRTLERvQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAER 1023
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEE-LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1024 GDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASF 1103
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1104 KRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLE 1183
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR 937

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1370478878 1184 LRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRE 1229
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 651-1220 3.70e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.25  E-value: 3.70e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  651 RDQLREQRKTLEQERARAgEQLAQAEQQLALERAERRGLQQAcgRLEQRQEQLEGQAALLGREKAQLQEQVgqvtcqkQA 730
Cdd:COG1196    195 LGELERQLEPLERQAEKA-ERYRELKEELKELEAELLLLKLR--ELEAELEELEAELEELEAELEELEAEL-------AE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  731 LE---EQLAQSLQDQEAQMGTLQQAL-----------QGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLES 796
Cdd:COG1196    265 LEaelEELRLELEELELELEEAQAEEyellaelarleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  797 SLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALE-SQALAHRE 875
Cdd:COG1196    345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERlERLEEELE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  876 ALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERS-- 953
Cdd:COG1196    425 ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADye 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  954 ---------LLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERG 1024
Cdd:COG1196    505 gflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRA 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1025 DVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFK 1104
Cdd:COG1196    585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1105 RSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLEL 1184
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1370478878 1185 RRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHG 1220
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 604-1159 4.82e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 103.86  E-value: 4.82e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  604 DLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERAR---AGEQLAQAEQQLA 680
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIA 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  681 LERAERRG-------LQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQAL 753
Cdd:COG1196    306 RLEERRREleerleeLEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  754 QGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAgLARQALQVEMEQL 833
Cdd:COG1196    386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE-AELEEEEEALLEL 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  834 QSDWEVQEMKLRQDTVRLQRQvaQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKElvtkSA 913
Cdd:COG1196    465 LAELLEEAALLEAALAELLEE--LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY----EA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  914 AEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSqqeqaqatISATTEELKA 993
Cdd:COG1196    539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA--------VDLVASDLRE 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  994 LQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALS 1073
Cdd:COG1196    611 ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1074 DEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGD---ARQELR 1150
Cdd:COG1196    691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDleeLERELE 770


                   ....*....
gi 1370478878 1151 ELHRQVRTL 1159
Cdd:COG1196    771 RLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 926-1534 1.43e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 1.43e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  926 LKQERDESLLQLEHkMQQALS-----LKETERSLlsEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFED 1000
Cdd:COG1196    170 YKERKEEAERKLEA-TEENLErlediLGELERQL--EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1001 AITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKD 1080
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1081 VLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLK 1160
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1161 AENQRRSGEAHELQaqcsQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAE 1240
Cdd:COG1196    407 EAEEALLERLERLE----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1241 LHSVTRKLQEAS-----------GVADALQARLDQACHRIHSLEQELAQAEGARQDAEAqlGRLCSTLRRGLGLQRQSPW 1309
Cdd:COG1196    483 LEELAEAAARLLllleaeadyegFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE--AALAAALQNIVVEDDEVAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1310 ASPEQPGSPTKGSDSSQALPGQQGTSPPARPHSPLRwpsptpGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQM 1389
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA------IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1390 ATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAgQEKRRLQEQ 1469
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE-EERELAEAE 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1470 LETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHrcQKAEVSLEPLRQMEQETLKRE-----EDVARLGA 1534
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEEL--LEEEALEELPEPPDLEELERElerleREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 646-1419 1.07e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERrglqqacGRLEQRQEQLEGQAALLGREKAQLQEQvgqvt 725
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV-------SELEEEIEELQKELYALANEISRLEQQ----- 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  726 cqKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALErqgrlaaEEAADLRVERDSLESSLLEAQQLA 805
Cdd:TIGR02168  304 --KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK-------EELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  806 TKLQEQLEEEARsaglARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKE 885
Cdd:TIGR02168  375 EELEEQLETLRS----KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  886 TLsltlAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDesllQLEHKMQQALSLKETERSLLSEELSRArrt 965
Cdd:TIGR02168  451 EL----QEELERLEEALEELREELEEAEQALDAAERELAQLQARLD----SLERLQENLEGFSEGVKALLKNQSGLS--- 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  966 lervqqeaqsqqeqaqaTISATTEELKALQAQFEDAITAhqrettALRESLQDLAAERGDVEREAERLRAQLTVAQEGLA 1045
Cdd:TIGR02168  520 -----------------GILGVLSELISVDEGYEAAIEA------ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFL 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1046 ALRQELQGVEESREGLHREAQEARRALSDEAREKDVLL---------------------------------------LFN 1086
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddldnalelakklrpgyrivtldgdLVR 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1087 SELRATICRAEQEKASFKRSKE--EKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQ 1164
Cdd:TIGR02168  657 PGGVITGGSAKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1165 RRSGEAH---ELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQ---EHLRESRGAEQTLR 1238
Cdd:TIGR02168  737 RLEAEVEqleERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKalrEALDELRAELTLLN 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1239 AELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLqrqspwaspeqpgsp 1318
Cdd:TIGR02168  817 EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE--------------- 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1319 tkgsdssqalpgqqgtspparphsplrwpsptpggRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSE 1398
Cdd:TIGR02168  882 -----------------------------------RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          810       820
                   ....*....|....*....|.
gi 1370478878 1399 AECRCARAQSRVGQLQKALAE 1419
Cdd:TIGR02168  927 LELRLEGLEVRIDNLQERLSE 947
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
487-1067 3.39e-16

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 84.71  E-value: 3.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  487 GREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERscraLETSQGRLQQLEEKVSGLREE 566
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDLRETIAETERE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  567 LASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQ 646
Cdd:PRK02224   274 REELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  647 LEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTC 726
Cdd:PRK02224   354 LEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  727 QKQALEEQLAQSLQDQEA-QMGTLQQALQGK---DALSEERAQLlakqEALErqgrlaaEEAADLRVERDSLESSLLEAQ 802
Cdd:PRK02224   434 TLRTARERVEEAEALLEAgKCPECGQPVEGSphvETIEEDRERV----EELE-------AELEDLEEEVEEVEERLERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  803 QLAtKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEmKLRQDTVRLQRQvAQQEREAQRALESQALAHREALAQLQR 882
Cdd:PRK02224   503 DLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAE-ELRERAAELEAE-AEEKREAAAEAEEEAEEAREEVAELNS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  883 EKETLSLTLaeekevarcqleQEKELVTKSAAEREALKGEIQSLkQERDESLLQLEHKMQQALSLKETERSLLSEELSRA 962
Cdd:PRK02224   580 KLAELKERI------------ESLERIRTLLAAIADAEDEIERL-REKREALAELNDERRERLAEKRERKRELEAEFDEA 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  963 RrtlervqqeaqsqqeqaqatisatTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRaqltvaqe 1042
Cdd:PRK02224   647 R------------------------IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE-------- 694

                          570       580
                   ....*....|....*....|....*...
gi 1370478878 1043 glaALRQELQGVEESR---EGLHREAQE 1067
Cdd:PRK02224   695 ---ELRERREALENRVealEALYDEAEE 719
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 422-1174 1.28e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.19  E-value: 1.28e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  422 QLKSSQALVASLQEQLSESRRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKllgREKAALEMVVEELK 501
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE---RSIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  502 GKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQR 581
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  582 DVVESEREGLRSALARAECSNADLELLVRRLKSegvEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKT- 660
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAGIEA---KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEy 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  661 --LEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQV--------GQVTCQKQA 730
Cdd:TIGR02169  479 drVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIevaagnrlNNVVVEDDA 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  731 LEEQLAQSLQDQEAQMGT------LQQALQGKDALSEERAQLLAKQEA-LERQGRLAAEEAADLRVERDSLESS--LLEA 801
Cdd:TIGR02169  559 VAKEAIELLKRRKAGRATflplnkMRDERRDLSILSEDGVIGFAVDLVeFDPKYEPAFKYVFGDTLVVEDIEAArrLMGK 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  802 QQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQ 881
Cdd:TIGR02169  639 YRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKI 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  882 REKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLeHKMQQALSlkETERSLLSEELSR 961
Cdd:TIGR02169  719 GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL-HKLEEALN--DLEARLSHSRIPE 795

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  962 ARRTLERVQQEAQSQQEQAQAtISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQ 1041
Cdd:TIGR02169  796 IQAELSKLEEEVSRIEARLRE-IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE 874

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1042 EGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASF---KRSKEEKEQKLLILE 1118
Cdd:TIGR02169  875 AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIedpKGEDEEIPEEELSLE 954

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370478878 1119 EAQAALQQEASALRAhlweLEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQ 1174
Cdd:TIGR02169  955 DVQAELQRVEEEIRA----LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 401-1162 2.48e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 2.48e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLsesrrelwaaqkLQQERAREQAREREAlrgQLEAQRLEVQQCR 480
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQL------------EELESKLDELAEELA---ELEEKLEELKEEL 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  481 ASCKLlgrEKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRrerscraLETSQGRLQQLEEKV 560
Cdd:TIGR02168  354 ESLEA---ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR-------LERLEDRRERLQQEI 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  561 SGLREELasVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSAL 640
Cdd:TIGR02168  424 EELLKKL--EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 nhlaLQLEQERDQLREQRKTLEQERARAGEQL-AQAEQQLALERAERRGLQQACGrlEQRQEQLEGQAAL---------- 709
Cdd:TIGR02168  502 ----EGFSEGVKALLKNQSGLSGILGVLSELIsVDEGYEAAIEAALGGRLQAVVV--ENLNAAKKAIAFLkqnelgrvtf 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  710 --LGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADL 787
Cdd:TIGR02168  576 lpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLV 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  788 RVE------RDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQvEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQERE 861
Cdd:TIGR02168  656 RPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA-ELRKELEELEEELEQLRKELEELSRQISALRKD 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  862 AQRALESQalahrEALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESllqlehkm 941
Cdd:TIGR02168  735 LARLEAEV-----EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL-------- 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  942 QQALSLKETERSLLSEELSRARRTLERVQQEaqsqqeqaqatISATTEELKALQAQFEDaitahqrettaLRESLQDLAA 1021
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERR-----------IAATERRLEDLEEQIEE-----------LSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1022 ERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKA 1101
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878 1102 SFK--------RSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAE 1162
Cdd:TIGR02168  940 NLQerlseeysLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQ 1008
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 421-1176 4.69e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 81.27  E-value: 4.69e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  421 LQLKSSQALVASLQEQLSESRRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVEEL 500
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISEL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  501 KGKADAADAEKQGLEAEAAELQRSLLLQAERR-EELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALstAQL 579
Cdd:TIGR02169  264 EKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEI--EEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  580 QRDvVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNhlalQLEQERDQLREQRK 659
Cdd:TIGR02169  342 ERE-IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN----ELKRELDRLQEELQ 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  660 TLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSl 739
Cdd:TIGR02169  417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA- 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  740 qdqEAQMGTLQQALQGKDALSEERAQ-------LLAKQEALERQGRLAAEEAADLRverdsLESSLLEAQQLATKLQEQL 812
Cdd:TIGR02169  496 ---EAQARASEERVRGGRAVEEVLKAsiqgvhgTVAQLGSVGERYATAIEVAAGNR-----LNNVVVEDDAVAKEAIELL 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  813 EEeaRSAGLARQALQVEMEQLQSDWEVQEMK----LRQDTVRLQRQVAQQEREAQR---ALESQALAHRE-------ALA 878
Cdd:TIGR02169  568 KR--RKAGRATFLPLNKMRDERRDLSILSEDgvigFAVDLVEFDPKYEPAFKYVFGdtlVVEDIEAARRLmgkyrmvTLE 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  879 QLQREKETL----SLTLAEEKEVARCQLEQEKELvtksAAEREALKGEIQSLKQERDEsllqlehkMQQALSLKETERSL 954
Cdd:TIGR02169  646 GELFEKSGAmtggSRAPRGGILFSRSEPAELQRL----RERLEGLKRELSSLQSELRR--------IENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  955 LSEELSRARRTLERVQQEAqsqqeqaqatisattEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLR 1034
Cdd:TIGR02169  714 ASRKIGEIEKEIEQLEQEE---------------EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1035 AQL-----TVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEE 1109
Cdd:TIGR02169  779 EALndleaRLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370478878 1110 KEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQ 1176
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 926-1631 6.90e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 6.90e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  926 LKQERDESLLQLEHkMQQALS-----LKETERSL--LSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQF 998
Cdd:TIGR02168  170 YKERRKETERKLER-TRENLDrlediLNELERQLksLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  999 EDA---ITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDE 1075
Cdd:TIGR02168  249 KEAeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1076 AREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQ 1155
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1156 VRTLKAENQRRSGEAHEL-QAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEahgqRLQEHLRESRGAE 1234
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE----EAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1235 QTLRAELHSVTRKLQEASGVADALQARLDQAcHRIHSLEQELAQ----AEGARQDAEAQLG-RLCSTLRRGLGLQRQSpW 1309
Cdd:TIGR02168  485 AQLQARLDSLERLQENLEGFSEGVKALLKNQ-SGLSGILGVLSElisvDEGYEAAIEAALGgRLQAVVVENLNAAKKA-I 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1310 ASPEQPGsptKGSDSSQALPGQQGTSPPARPHSPLRWPSPTPGGRSSELMDVATVQDILRDF------VQKLREAQR--- 1380
Cdd:TIGR02168  563 AFLKQNE---LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDNALElak 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1381 ------------------------ERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARA 1436
Cdd:TIGR02168  640 klrpgyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1437 ARAL-------QKEALRRLELEH---LASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQ 1506
Cdd:TIGR02168  720 ELEElsrqisaLRKDLARLEAEVeqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1507 KAEVSLEPLRQMEQETlkrEEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQrLQDLTAQHQRDL 1586
Cdd:TIGR02168  800 ALREALDELRAELTLL---NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE-LEELIEELESEL 875

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1370478878 1587 aTEAERLHGARPQATQALESQEWTHQQQVKVLEEQVASLKEQLDQ 1631
Cdd:TIGR02168  876 -EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1031-1546 8.36e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 8.36e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1031 ERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEK 1110
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1111 EQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQ---------------- 1174
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEeeleelaeellealra 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1175 -AQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASG 1253
Cdd:COG1196    395 aAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1254 VADALQAR---LDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLQRQSPWASPE-----------QPGSPT 1319
Cdd:COG1196    475 LEAALAELleeLAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEaaleaalaaalQNIVVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1320 KGSDSSQALPGQQGTSPPARPHSPLRWPSPTPGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEA 1399
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1400 ECRcaRAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEE 1479
Cdd:COG1196    635 ALR--RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370478878 1480 SRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQMEQETLKREEDVARLGAEKEQLDQSLNSL 1546
Cdd:COG1196    713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 499-1181 1.08e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.11  E-value: 1.08e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  499 ELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQL-EEKVSGLREELASVREALstA 577
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEI--A 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  578 QLQRDVVESEREglrsaLARAECSNADLELLVRRLKSEGVEQRDSLAAMA----ALMEGLAQDKSALNHLALQLEQERDQ 653
Cdd:TIGR02169  305 SLERSIAEKERE-----LEDAEERLAKLEAEIDKLLAEIEELEREIEEERkrrdKLTEEYAELKEELEDLRAELEEVDKE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  654 LREQRKTLEQERaragEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEE 733
Cdd:TIGR02169  380 FAETRDELKDYR----EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  734 QLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSL-----LEAQQLATKL 808
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgvhgTVAQLGSVGE 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  809 QEQLEEEArSAGLARQALQVEMEQL--QSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKET 886
Cdd:TIGR02169  536 RYATAIEV-AAGNRLNNVVVEDDAVakEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEP 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  887 L------SLTLAEEKEVARCQLEQ------EKELVTKSAA-------------EREALKGEIQSLkQERDESLLQLEHKM 941
Cdd:TIGR02169  615 AfkyvfgDTLVVEDIEAARRLMGKyrmvtlEGELFEKSGAmtggsraprggilFSRSEPAELQRL-RERLEGLKRELSSL 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  942 QQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAqatisattEELKALQAQFEDAITAHQRETTALRESLQDLAA 1021
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE--------EKLKERLEELEEDLSSLEQEIENVKSELKELEA 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1022 ERGDVEREAERLRAQL-----TVAQEGLAALRQELQGVEESR--------------EGLHREAQEARRALSDEAREKDVL 1082
Cdd:TIGR02169  766 RIEELEEDLHKLEEALndleaRLSHSRIPEIQAELSKLEEEVsriearlreieqklNRLTLEKEYLEKEIQELQEQRIDL 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1083 LLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAE 1162
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          730
                   ....*....|....*....
gi 1370478878 1163 NQRRSGEAHELQAQCSQEV 1181
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDE 944
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 76-814 1.19e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 1.19e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878   76 QAGVQEPTATVARVQEENELLQEELTRLGDLLAQASAERDELASRcrvvSEQLQARLETTEAQLrrseLEHSVDLEEALG 155
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK----LDELAEELAELEEKL----EELKEELESLEA 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  156 RLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGELELRRWAQRQTRSGGLGQPRDLLLLWRQAV 235
Cdd:TIGR02168  359 ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL 438

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  236 vlGTDLAELrvatERGLADLQADTARTARRLHTAC--LNLDSNLRLSASSTASTLGQQLRDKAGEMLQLQGRWDAEKVAL 313
Cdd:TIGR02168  439 --QAELEEL----EEELEELQEELERLEEALEELReeLEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALL 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  314 QARL---SEQTLLVEKLTEQNEQKAKTIAALRTDLQNLVAQEDA---------------RCLELAGSSITElGEPRRPLR 375
Cdd:TIGR02168  513 KNQSglsGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNaakkaiaflkqnelgRVTFLPLDSIKG-TEIQGNDR 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  376 SPQRATSPHQGASPPHICSPATLDPALQAM--RAAIERRWRREQELCLQLKSSQALV---------------------AS 432
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELAKKLRPGYRIVtldgdlvrpggvitggsaktnSS 671

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  433 LQEQLSEsRRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRasckllgREKAALEMVVEELKGKADAADAEKQ 512
Cdd:TIGR02168  672 ILERRRE-IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLEAEVE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  513 GLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAqlqRDVVESEREGLR 592
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL---RAELTLLNEEAA 820

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  593 SALARAECSNADLELLVRRLksegveqrdslaamaalmEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQL 672
Cdd:TIGR02168  821 NLRERLESLERRIAATERRL------------------EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  673 AQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQA 752
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK 962

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370478878  753 LQGKDALSEERAQLLakQEALERQGR---LAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEE 814
Cdd:TIGR02168  963 IEDDEEEARRRLKRL--ENKIKELGPvnlAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 851-1482 1.57e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 1.57e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  851 LQRQVAQQEREAQRALESQALahREALAQLQREKETLSL-TLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQE 929
Cdd:COG1196    198 LERQLEPLERQAEKAERYREL--KEELKELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  930 RDESLLQLEhKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRET 1009
Cdd:COG1196    276 LEELELELE-EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1010 TALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQgveesregLHREAQEARRALSDEAREKDVLLLFNSEL 1089
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE--------LAAQLEELEEAEEALLERLERLEEELEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1090 RATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGE 1169
Cdd:COG1196    427 EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1170 AHELQAqcsqevlelrrqAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELhsvtrkLQ 1249
Cdd:COG1196    507 LEGVKA------------ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL------KA 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1250 EASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLQRQSPWAspeqpgsptkgsdssqalp 1329
Cdd:COG1196    569 AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA------------------- 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1330 gqqgtsppARPHSPLRWPSPTPGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSR 1409
Cdd:COG1196    630 --------ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370478878 1410 VGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEESRR 1482
Cdd:COG1196    702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774
PTZ00121 PTZ00121
MAEBL; Provisional
 435-1158 1.59e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.80  E-value: 1.59e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  435 EQLSESRRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVEELKGKADAADAEKQGL 514
Cdd:PTZ00121  1091 EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEAR 1170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  515 EAEAAELQRSLLLQAERREELALRRERSCRALEtsQGRLQQLEEKVSGLR--EELASVREALSTAQLQRDVVESER-EGL 591
Cdd:PTZ00121  1171 KAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARkaEDAKKAEAVKKAEEAKKDAEEAKKaEEE 1248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  592 RSALARAECSNADLELLVRR---LKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLR---EQRKTLEQER 665
Cdd:PTZ00121  1249 RNNEEIRKFEEARMAHFARRqaaIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKkadEAKKKAEEAK 1328

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  666 ARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEqvgqvtCQKQALEEQLAQSLQDQEAQ 745
Cdd:PTZ00121  1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA------AKKKAEEKKKADEAKKKAEE 1402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  746 MGtlQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQlATKLQEQlEEEARSAGLARQA 825
Cdd:PTZ00121  1403 DK--KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK-AEEAKKK-AEEAKKADEAKKK 1478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  826 LQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQalaHREALAQLQREKETLSLTLAEEKEVAR--CQLE 903
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAK---KADEAKKAEEAKKADEAKKAEEKKKADelKKAE 1555

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  904 QEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHK-MQQALSLKETERSLLSEELSR---ARRTLERVQQEAQSQQEQ 979
Cdd:PTZ00121  1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEArIEEVMKLYEEEKKMKAEEAKKaeeAKIKAEELKKAEEEKKKV 1635

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  980 AQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERlraqltVAQEGLAALRQELQGVEESRE 1059
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK------KAAEALKKEAEEAKKAEELKK 1709

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1060 glhREAQEARRAlSDEAREKDVLLLFNSELRAticRAEQEKASFKRSKEEKEQKLLIlEEAQAALQQEASALRAHLWELE 1139
Cdd:PTZ00121  1710 ---KEAEEKKKA-EELKKAEEENKIKAEEAKK---EAEEDKKKAEEAKKDEEEKKKI-AHLKKEEEKKAEEIRKEKEAVI 1781

                          730
                   ....*....|....*....
gi 1370478878 1140 QAGGDARQELRELHRQVRT 1158
Cdd:PTZ00121  1782 EEELDEEDEKRRMEVDKKI 1800
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 555-1290 1.93e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 1.93e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  555 QLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAEcsnADLELLVRRLKSEGVEQRDSLAAMAALMEGLA 634
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE---RYQALLKEKREYEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  635 QDKSALnhlalqlEQERDQLREQRKTLEQERARAGEQLAQAEQQL-ALERAERRGLQQACGRLEQRQEQLEGQAALLGRE 713
Cdd:TIGR02169  244 RQLASL-------EEELEKLTEEISELEKRLEEIEQLLEELNKKIkDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  714 KAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDS 793
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  794 LESSLLEAQQLATKLQEQLEEEARSAGLARQALQV---EMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREaqralESQA 870
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGieaKINELEEEKEDKALEIKKQEWKLEQLAADLSKY-----EQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  871 LAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKG----------------------------- 921
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlgsvgeryataievaagnrlnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  922 -----------EIQSLKQ-----------------ERDESLLQLEHKMQQALSLKETER------------SLLSEELSR 961
Cdd:TIGR02169  552 vvveddavakeAIELLKRrkagratflplnkmrdeRRDLSILSEDGVIGFAVDLVEFDPkyepafkyvfgdTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  962 ARRTLERVQQEaqsqqeqaqaTISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQ 1041
Cdd:TIGR02169  632 ARRLMGKYRMV----------TLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1042 EGLAALRQELQGVEESREGLHREAQEARRalsDEAREKDVLllfnSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQ 1121
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQ---EEEKLKERL----EELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1122 AALQQEASALRAHLweleqaggdARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQevLELRRQAAKAEAKHEGARKE 1201
Cdd:TIGR02169  775 HKLEEALNDLEARL---------SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR--LTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1202 VLGLQRK-LAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAE 1280
Cdd:TIGR02169  844 DLKEQIKsIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810
                   ....*....|
gi 1370478878 1281 GARQDAEAQL 1290
Cdd:TIGR02169  924 AKLEALEEEL 933
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
558-1158 2.78e-14

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 78.42  E-value: 2.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  558 EKVSGLREELASVREALSTAQLQRDVVESEREgLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAmaALMEGLAQDK 637
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIELLEPIRE-LAERYAAARERLAELEYLRAALRLWFAQRRLELLE--AELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  638 SALNHLALQLEQERDQLREQRKTLEQERARA-GEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALlgrEKAQ 716
Cdd:COG4913    305 ARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPA---SAEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  717 LQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEAL-ERQGRLAAEEAADLRVERDSLE 795
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIpARLLALRDALAEALGLDEAELP 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  796 --SSLLEAQQLATKLQEQLEEEARSAGLarqALQVEMEQLQ--SDWeVQEMKLRQdTVRLQRQVAQQEREAQRALESQAL 871
Cdd:COG4913    462 fvGELIEVRPEEERWRGAIERVLGGFAL---TLLVPPEHYAaaLRW-VNRLHLRG-RLVYERVRTGLPDPERPRLDPDSL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  872 AHR------EALAQLQREketlsltLAEEKEVARC----QLEQEKELVT-----KSAAEREALKGeiqslkQERDESLLQ 936
Cdd:COG4913    537 AGKldfkphPFRAWLEAE-------LGRRFDYVCVdspeELRRHPRAITragqvKGNGTRHEKDD------RRRIRSRYV 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  937 LEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQ--ATISATTEELKALQAQfEDAITAHQRETTALRE 1014
Cdd:COG4913    604 LGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASA-EREIAELEAELERLDA 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1015 SLQDLAAergdVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRatiC 1094
Cdd:COG4913    683 SSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEER---F 755

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878 1095 RAEQEKASFKRSKEEKEQKLLILEEAQAALQQE-ASALRAHL--WELEQAGGDA----RQELRELHRQVRT 1158
Cdd:COG4913    756 AAALGDAVERELRENLEERIDALRARLNRAEEElERAMRAFNreWPAETADLDAdlesLPEYLALLDRLEE 826
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 151-803 1.71e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 1.71e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  151 EEALGRLEAAEERstgLCQVNALLRE---QLEHMKK-ANDAlgRELAGMTGSVQRLQGELELRRWAQRQtrsgglgqpRD 226
Cdd:COG1196    175 EEAERKLEATEEN---LERLEDILGElerQLEPLERqAEKA--ERYRELKEELKELEAELLLLKLRELE---------AE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  227 LLLLWRQAVVLGTDLAELRvaTERGLADLQADTARTARRLHTACLNLDSNLRLSASSTASTLGQQLRDKAGEMLQLQGRW 306
Cdd:COG1196    241 LEELEAELEELEAELEELE--AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  307 DAEKVALQARLSEQTLLVEKLTEQNEQKAKTIAALRTDLQNLVAQEDARCLELAgssitelgeprrplrspqratsphqg 386
Cdd:COG1196    319 EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA-------------------------- 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  387 aspphicspatldpALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELwaaQKLQQERAREQAREREALR 466
Cdd:COG1196    373 --------------ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL---ERLEEELEELEEALAELEE 435

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  467 GQLEAQRLEVQQCRASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRAL 546
Cdd:COG1196    436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  547 ETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLR--SALARAECSNADLELLVRRLKSEGVEQRDSLA 624
Cdd:COG1196    516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAALAAALARG 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  625 AMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLE 704
Cdd:COG1196    596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  705 GQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEA 784
Cdd:COG1196    676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                          650
                   ....*....|....*....
gi 1370478878  785 ADLRVERDSLESSLLEAQQ 803
Cdd:COG1196    756 LPEPPDLEELERELERLER 774
PTZ00121 PTZ00121
MAEBL; Provisional
 536-1258 5.28e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.79  E-value: 5.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  536 ALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESER-EGLRSALARAECSNADLELLVRRLKS 614
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  615 EGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAErrglqqacg 694
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAE--------- 1233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  695 rlEQRQEQLEGQAAllgrEKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMG-TLQQALQGKDALSEERAQLLAKQEAL 773
Cdd:PTZ00121  1234 --EAKKDAEEAKKA----EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAdELKKAEEKKKADEAKKAEEKKKADEA 1307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  774 ERQgrlaAEEAAdlrvERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQalqvEMEQLQSDWEVQEMKLRQDTVRLQR 853
Cdd:PTZ00121  1308 KKK----AEEAK----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA----EAEAAADEAEAAEEKAEAAEKKKEE 1375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  854 QVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARcqlEQEKELVTKSAAEREALKGEiqsLKQERDES 933
Cdd:PTZ00121  1376 AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADEAKKKAE---EAKKADEA 1449

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  934 LLQLEHKMQQALSLKETERSLLSEELSRA---RRTLERVQQEAQSQQEQAQATISATTEELKALQA-QFEDAITAHqrET 1009
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKaeeAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAkKAEEAKKAD--EA 1527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1010 TALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRAlsDEAREKDVLLLFNSE- 1088
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA--EEARIEEVMKLYEEEk 1605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1089 -LRATICRAEQE---KASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKA--E 1162
Cdd:PTZ00121  1606 kMKAEEAKKAEEakiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKaeE 1685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1163 NQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHgQRLQEHLRESRGAEQTLRAELH 1242
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED-KKKAEEAKKDEEEKKKIAHLKK 1764

                          730
                   ....*....|....*.
gi 1370478878 1243 SVTRKLQEASGVADAL 1258
Cdd:PTZ00121  1765 EEEKKAEEIRKEKEAV 1780
PTZ00121 PTZ00121
MAEBL; Provisional
 501-1247 6.41e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.41  E-value: 6.41e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  501 KGKADAADAEKQGLeAEAAELQRSLLLQAERREELALRRERSCRALETSQgRLQQLEEKVSGLREELASVREALSTAQLQ 580
Cdd:PTZ00121  1086 DNRADEATEEAFGK-AEEAKKTETGKAEEARKAEEAKKKAEDARKAEEAR-KAEDARKAEEARKAEDAKRVEIARKAEDA 1163

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  581 RDVVESEREglrSALARAECSNADLEllVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKT 660
Cdd:PTZ00121  1164 RKAEEARKA---EDAKKAEAARKAEE--VRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKD 1238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  661 LEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGR--EKAQLQEQVGQV-TCQKQALEEQLAQ 737
Cdd:PTZ00121  1239 AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKkaDEAKKAEEKKKAdEAKKKAEEAKKAD 1318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  738 SLQDQEAQMGTLQQALQgKDALSEERAQLLAKQEALERQGRLaaeEAADLRVERDSLESSllEAQQLATKLQEQLEEEAR 817
Cdd:PTZ00121  1319 EAKKKAEEAKKKADAAK-KKAEEAKKAAEAAKAEAEAAADEA---EAAEEKAEAAEKKKE--EAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  818 SAGLARQALQVE--MEQLQSDWE----VQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKetlsltl 891
Cdd:PTZ00121  1393 ADEAKKKAEEDKkkADELKKAAAakkkADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK------- 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  892 AEEKEVArcqleQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKmQQALSLKETERSLLSEELSRARRTLERVQQ 971
Cdd:PTZ00121  1466 AEEAKKA-----DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK-KKADEAKKAEEAKKADEAKKAEEAKKADEA 1539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  972 EAQSQQEQAQATISAttEELKALQA--QFEDAITAHQRETTALReslqdlaaeRGDVEREAE--RLRAQLTVAQEGLAAL 1047
Cdd:PTZ00121  1540 KKAEEKKKADELKKA--EELKKAEEkkKAEEAKKAEEDKNMALR---------KAEEAKKAEeaRIEEVMKLYEEEKKMK 1608

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1048 RQELQGVEESREglhrEAQEARRAlsdEAREKDVLLLFNSElraticrAEQEKASFKRSKEEKEQKLLILEEAQAALQQE 1127
Cdd:PTZ00121  1609 AEEAKKAEEAKI----KAEELKKA---EEEKKKVEQLKKKE-------AEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1128 ASALrahlwELEQAGGDARQELRELHRqvrtlKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQR 1207
Cdd:PTZ00121  1675 KKAE-----EAKKAEEDEKKAAEALKK-----EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 1370478878 1208 KlAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRK 1247
Cdd:PTZ00121  1745 K-AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 398-932 6.59e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 6.59e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  398 LDPALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKLQQE---RAREQAREREALRGQLEAQRL 474
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEElesRLEELEEQLETLRSKVAQLEL 393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  475 EVQQCRASCKLLGREKAALEMVVEELKgkADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQ 554
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  555 QLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKsegVEQRDSLAAMAAL----- 629
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS---VDEGYEAAIEAALggrlq 548

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  630 ---MEGLAQDKSALNHLA-------------------------------------------------------------- 644
Cdd:TIGR02168  549 avvVENLNAAKKAIAFLKqnelgrvtflpldsikgteiqgndreilkniegflgvakdlvkfdpklrkalsyllggvlvv 628

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  645 --------------------------------------------LQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLA 680
Cdd:TIGR02168  629 ddldnalelakklrpgyrivtldgdlvrpggvitggsaktnssiLERRREIEELEEKIEELEEKIAELEKALAELRKELE 708

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  681 LERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQ-------VTCQKQALEEQLAQS---LQDQEAQMGTLQ 750
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQlskelteLEAEIEELEERLEEAeeeLAEAEAEIEELE 788

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  751 Q-ALQGKDALSEERAQLLAKQEALERQgrlaAEEAADLRVERDSLESSLLEAQQLATKLQEQLE---EEARSAGLARQAL 826
Cdd:TIGR02168  789 AqIEQLKEELKALREALDELRAELTLL----NEEAANLRERLESLERRIAATERRLEDLEEQIEelsEDIESLAAEIEEL 864

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  827 QVEMEQLQSDWEV---------QEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEV 897
Cdd:TIGR02168  865 EELIEELESELEAllnerasleEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 1370478878  898 ARCQ----LEQEKELVTKSAAEREALKGEIQSLKQERDE 932
Cdd:TIGR02168  945 LSEEysltLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 851-1625 6.93e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 6.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  851 LQRQVAQQEREAQRALESQALahREALAQLQREKETLSLT-LAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLK-- 927
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKEL--KAELRELELALLVLRLEeLREELEELQEELKEAEEELEELTAELQELEEKLEELRle 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  928 -QERDESLLQLEHKMQ---QALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQAT------ISATTEELKALQAQ 997
Cdd:TIGR02168  276 vSELEEEIEELQKELYalaNEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELaeelaeLEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  998 FEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAR 1077
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1078 EKDVLLLfnSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEqaggDARQELRELHRQVR 1157
Cdd:TIGR02168  436 KELQAEL--EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE----RLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1158 TLKAENQRRSGEAHELQaqcsqevlelrrQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAhgQRLQEHLRESRGAEQTL 1237
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLS------------ELISVDEGYEAAIEAALGGRLQAVVVENLNAA--KKAIAFLKQNELGRVTF 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1238 RAELHSVTRKLQEASGVADALQARLDQACHrihSLEQELAQAEGARQDAEAQLgRLCSTLRRGLGLQRQSP----WASPE 1313
Cdd:TIGR02168  576 LPLDSIKGTEIQGNDREILKNIEGFLGVAK---DLVKFDPKLRKALSYLLGGV-LVVDDLDNALELAKKLRpgyrIVTLD 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1314 QPGSPTKGSDSSQALPGQQGTSPPARPHSPLRWPSPTPGGRSSEL-MDVATVQDILRDFVQKLREAQRERDDSRIQMATL 1392
Cdd:TIGR02168  652 GDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELeKALAELRKELEELEEELEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1393 SSRLSEAECRCARAQSRVGQLQK---------------------ALAEAEEGQRRVEGALSSARAARALQKEALRRLELE 1451
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKelteleaeieeleerleeaeeELAEAEAEIEELEAQIEQLKEELKALREALDELRAE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1452 HlasvRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLR----QMEQETLKREE 1527
Cdd:TIGR02168  812 L----TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELEseleALLNERASLEE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1528 DVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMeQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALESQ 1607
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQL-ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDD 966

                          810
                   ....*....|....*...
gi 1370478878 1608 EWTHQQQVKVLEEQVASL 1625
Cdd:TIGR02168  967 EEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 903-1637 8.05e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.02  E-value: 8.05e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  903 EQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSR---ARRTLE-RVQQEAQSQQE 978
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKaeeARKAEDaKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  979 QAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAqltvAQEGLAAlrQELQGVEESR 1058
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK----AEDAKKA--EAVKKAEEAK 1236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1059 eglhREAQEARRA----LSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAh 1134
Cdd:PTZ00121  1237 ----KDAEEAKKAeeerNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKA- 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1135 lwELEQAGGDARQELRELHRQVRTLK--AENQRRSGEAHELQAQCSQEVLELRRQAAKA-EAKHEGARKEVLGLQRKLAE 1211
Cdd:PTZ00121  1312 --EEAKKADEAKKKAEEAKKKADAAKkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaEKKKEEAKKKADAAKKKAEE 1389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1212 VEAAGEAHgQRLQEHLRES----RGAEQTLRAElhsVTRKLQEASGVADALQARLDQA--CHRIHSLEQELAQAEGARQD 1285
Cdd:PTZ00121  1390 KKKADEAK-KKAEEDKKKAdelkKAAAAKKKAD---EAKKKAEEKKKADEAKKKAEEAkkADEAKKKAEEAKKAEEAKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1286 AEAQlgRLCSTLRRGLGLQRQSPWASPEQPGSPTKGSDSSQALPGQQgTSPPARPHSPLRWPSPTPGGRSSELMDVATVQ 1365
Cdd:PTZ00121  1466 AEEA--KKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK-KADEAKKAEEAKKADEAKKAEEAKKADEAKKA 1542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1366 DILRDfVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKAlaeaeegqrRVEGALSSARAARALQKEAL 1445
Cdd:PTZ00121  1543 EEKKK-ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEA 1612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1446 RRLELEHLASVRAAGQEKRRlqEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQMEQETLKR 1525
Cdd:PTZ00121  1613 KKAEEAKIKAEELKKAEEEK--KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1526 EEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQrlqdltAQHQRDLATEAERLHGARPQATQALE 1605
Cdd:PTZ00121  1691 AEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE------AEEDKKKAEEAKKDEEEKKKIAHLKK 1764

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1370478878 1606 SQEWTHQQQVKvleEQVASLKEQLDQEVQWRQ 1637
Cdd:PTZ00121  1765 EEEKKAEEIRK---EKEAVIEEELDEEDEKRR 1793
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 405-1202 9.46e-13

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 73.83  E-value: 9.46e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  405 MRAAIERRWRREQELCL--QLKSSQALVASLQEQLSESRRELwaAQKLQQERAREQ----AREREALRGQLEAQRLEVQQ 478
Cdd:COG3096    274 MRHANERRELSERALELrrELFGARRQLAEEQYRLVEMAREL--EELSARESDLEQdyqaASDHLNLVQTALRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  479 CRASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEA-------AELQRSLLLQAER----REEL-ALRRERSCRAL 546
Cdd:COG3096    352 YQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVdslksqlADYQQALDVQQTRaiqyQQAVqALEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  547 -----ETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRS---ALARAECSNADLELLVR-RLKSEGV 617
Cdd:COG3096    432 pdltpENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiagEVERSQAWQTARELLRRyRSQQALA 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  618 EQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLE 697
Cdd:COG3096    512 QRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLR 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  698 QRQEQLEGQAALLGREKAQLqeqvgqvtcqkQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQG 777
Cdd:COG3096    592 ARIKELAARAPAWLAAQDAL-----------ERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQI 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  778 R--LAAEEAADLRVER--DSLESSLLEAQQLATKLQEQLEEEARsAGLARQALQVE-----MEQLQ-------------- 834
Cdd:COG3096    661 ErlSQPGGAEDPRLLAlaERLGGVLLSEIYDDVTLEDAPYFSAL-YGPARHAIVVPdlsavKEQLAgledcpedlylieg 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  835 -------SDWEVQEMKLRQDTVRLQRQVaQQEREAQRALESQAlAHREALAQLQREKETLSLTLAEEK-EVARCQ-LEQE 905
Cdd:COG3096    740 dpdsfddSVFDAEELEDAVVVKLSDRQW-RYSRFPEVPLFGRA-AREKRLEELRAERDELAEQYAKASfDVQKLQrLHQA 817

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  906 ------KELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQalslketerslLSEELSRARRTLERVQQEAQSQQEQ 979
Cdd:COG3096    818 fsqfvgGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQ-----------LRQQLDQLKEQLQLLNKLLPQANLL 886

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  980 AQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREaERLRAQLTVAQEGLAALRQELQGVEESRE 1059
Cdd:COG3096    887 ADETLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQF-EQLQADYLQAKEQQRRLKQQIFALSEVVQ 965

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1060 GLHREAQEARRALSDEAREkdvlllFNSELRATICRAEQEKAsfkRSKEEKEQKLLILEEAQAALQQEASALRAH---LW 1136
Cdd:COG3096    966 RRPHFSYEDAVGLLGENSD------LNEKLRARLEQAEEARR---EAREQLRQAQAQYSQYNQVLASLKSSRDAKqqtLQ 1036

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1137 ELEQ------------AGGDARQELRELHRQVRTLKaenQRRSgeahELQAQ---CSQEVLELRRQAAKAEAKHEGARKE 1201
Cdd:COG3096   1037 ELEQeleelgvqadaeAEERARIRRDELHEELSQNR---SRRS----QLEKQltrCEAEMDSLQKRLRKAERDYKQEREQ 1109


                   .
gi 1370478878 1202 V 1202
Cdd:COG3096   1110 V 1110
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
647-1187 1.58e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 72.77  E-value: 1.58e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  647 LEQERDQLREQRKTLEQERARAGEQLAQAEQQLAlERAERRglqQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTC 726
Cdd:PRK02224   211 LESELAELDEEIERYEEQREQARETRDEADEVLE-EHEERR---EELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  727 QKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLAt 806
Cdd:PRK02224   287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA- 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  807 klqEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQ-----RQVAQQEREAQRALESQALAHREALAQLQ 881
Cdd:PRK02224   366 ---AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGnaedfLEELREERDELREREAELEATLRTARERV 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  882 REKETLsltlAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLlsEELSR 961
Cdd:PRK02224   443 EEAEAL----LEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRI--ERLEE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  962 ARRTLERVQQEAQSQQEQAQATIS---ATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLT 1038
Cdd:PRK02224   517 RREDLEELIAERRETIEEKRERAEelrERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRT 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1039 VAQEgLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRatICRAEQEKASFKRSKEEKEQKLLILE 1118
Cdd:PRK02224   597 LLAA-IADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELR 673

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878 1119 EAQAALQQEASALRAHLWELEqaggdarqELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQ 1187
Cdd:PRK02224   674 EERDDLQAEIGAVENELEELE--------ELRERREALENRVEALEALYDEAEELESMYGDLRAELRQR 734
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
127-263 2.53e-12

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 67.37  E-value: 2.53e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  127 QLQARLETTEAQLRRSELEHSVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGEL 206
Cdd:pfam15035   50 ELLLRKLTLEPRLQRLEREHSADLEEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREEL 129

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878  207 ELR--RWAQRQTRSGGL--GQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTA 263
Cdd:pfam15035  130 EQKesEWRKEEEAFNEYlsSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
527-1070 3.55e-12

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 71.87  E-value: 3.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  527 LQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAecSNADLE 606
Cdd:COG4913    264 YAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGN--GGDRLE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  607 LLVRRLKSEGVEQRDSLAAMAALMEGLAQdksalnhLALQLEQERDQLREQRktleqerarageqlAQAEQQLALERAER 686
Cdd:COG4913    342 QLEREIERLERELEERERRRARLEALLAA-------LGLPLPASAEEFAALR--------------AEAAALLEALEEEL 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  687 RGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQM-----------------GTL 749
Cdd:COG4913    401 EALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELpfvgelievrpeeerwrGAI 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  750 QQAL--QGKDALSEER--AQLLAKQEALERQGRLAAEEAadlRVERDSLESSLLEAQQLATKLQ---------------- 809
Cdd:COG4913    481 ERVLggFALTLLVPPEhyAAALRWVNRLHLRGRLVYERV---RTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgr 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  810 ----------EQLEEEARS---AGLARQ----------------------------ALQVEMEQLQSdwEVQEMKLRQDT 848
Cdd:COG4913    558 rfdyvcvdspEELRRHPRAitrAGQVKGngtrhekddrrrirsryvlgfdnraklaALEAELAELEE--ELAEAEERLEA 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  849 VRLQRQVAQQEREAQRALESQA------LAHREALAQLQREKETLSLTLAEEKEVARcQLEQEKELVTKSAAEREALKGE 922
Cdd:COG4913    636 LEAELDALQERREALQRLAEYSwdeidvASAEREIAELEAELERLDASSDDLAALEE-QLEELEAELEELEEELDELKGE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  923 IQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSrARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAI 1002
Cdd:COG4913    715 IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE-ERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAM 793

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370478878 1003 TAHQRETTALRESLQDLAAERGDVEREAERLRAqltvaqEGLAALRQELQG-----VEESREGLHREAQEARR 1070
Cdd:COG4913    794 RAFNREWPAETADLDADLESLPEYLALLDRLEE------DGLPEYEERFKEllnenSIEFVADLLSKLRRAIR 860
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 855-1632 8.22e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 8.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  855 VAQQEREAQRALESQALAHR--EALAQLQREKETLSLTLAEEKEVA----RCQLEQEKELVTKSAAEREALKGEIQSLKQ 928
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEEniERLDLIIDEKRQQLERLRREREKAeryqALLKEKREYEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  929 ERDEsllqlehkMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRE 1008
Cdd:TIGR02169  245 QLAS--------LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1009 TTALRESLQDLAAERGDVEREAERLRAQLTV--------------AQEGLAALRQELQGVEEsreglhrEAQEARRALSD 1074
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEerkrrdklteeyaeLKEELEDLRAELEEVDK-------EFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1075 EAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHR 1154
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1155 QVRTLKAENQRRSGEAHELQaqcsqevlelrRQAAKAEAKHEGARKEVLGlqrklaeveaageahGQRLQEHLRESRGAE 1234
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQ-----------RELAEAEAQARASEERVRG---------------GRAVEEVLKASIQGV 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1235 QTLRAELHSVTRKLQEAsgVADALQARLDQAChrihsLEQELAQAEGARQDAEAQLGRLCStlrrgLGLQRQspwaspeq 1314
Cdd:TIGR02169  524 HGTVAQLGSVGERYATA--IEVAAGNRLNNVV-----VEDDAVAKEAIELLKRRKAGRATF-----LPLNKM-------- 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1315 pgsptkgsdssqalpgqqgtsppARPHSPLRWPSPTpgGRSSELMDVATVQD--------ILRD--FVQKLREAQRERDd 1384
Cdd:TIGR02169  584 -----------------------RDERRDLSILSED--GVIGFAVDLVEFDPkyepafkyVFGDtlVVEDIEAARRLMG- 637

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1385 sRIQMATLSSRLSEA---------------------ECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKE 1443
Cdd:TIGR02169  638 -KYRMVTLEGELFEKsgamtggsraprggilfsrsePAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1444 ALRRLELEHLASVRAAGQEKRRL---QEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSL--EPLRQM 1518
Cdd:TIGR02169  717 KIGEIEKEIEQLEQEEEKLKERLeelEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshSRIPEI 796

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1519 EQETLKREEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEME--QAHTQRLQDLTAQHQRDLATEAERLHGA 1596
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKeqIKSIEKEIENLNGKKEELEEELEELEAA 876

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1370478878 1597 RPQATQA---LESQEWTHQQQVKVLEEQVASLKEQLDQE 1632
Cdd:TIGR02169  877 LRDLESRlgdLKKERDELEAQLRELERKIEELEAQIEKK 915
PTZ00121 PTZ00121
MAEBL; Provisional
 580-1251 1.59e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.78  E-value: 1.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  580 QRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRK 659
Cdd:PTZ00121  1044 EKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKK 1123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  660 TleqERARAGEQLAQAEQQLALERAeRRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSL 739
Cdd:PTZ00121  1124 A---EDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDA 1199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  740 QDQEA--QMGTLQQALQGKDALSEERAQLLAKQEALERQgrlaAEEAADLRVERDSLESSLLEAQQLATKLQEQLE---E 814
Cdd:PTZ00121  1200 RKAEAarKAEEERKAEEARKAEDAKKAEAVKKAEEAKKD----AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAikaE 1275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  815 EARSAGLARQALQV----EMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREA-----LAQLQREKE 885
Cdd:PTZ00121  1276 EARKADELKKAEEKkkadEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAkkaaeAAKAEAEAA 1355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  886 TLSLTLAEEK-EVARCQLEQEKElvtksaaEREALKGEIQSLKQErDESLLQLEHKMQQALSLKETErsllsEELSRARR 964
Cdd:PTZ00121  1356 ADEAEAAEEKaEAAEKKKEEAKK-------KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKKAA-----AAKKKADE 1422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  965 TLERVQQEAQSQQEQAQATISATTEELKAlqaQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGL 1044
Cdd:PTZ00121  1423 AKKKAEEKKKADEAKKKAEEAKKADEAKK---KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1045 AALRQ---------ELQGVEESREGLH-REAQEARRAlsDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKL 1114
Cdd:PTZ00121  1500 DEAKKaaeakkkadEAKKAEEAKKADEaKKAEEAKKA--DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKN 1577

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1115 LILEEAQAALQQEASALrahlweleqaggdarQELRELHRQVRTLKAENQRRSGEAhelqaqcsqevlelrRQAAKAEAK 1194
Cdd:PTZ00121  1578 MALRKAEEAKKAEEARI---------------EEVMKLYEEEKKMKAEEAKKAEEA---------------KIKAEELKK 1627

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370478878 1195 HEGARKEVLGLQRKLAEveaageahgqrlqehlrESRGAEQTLRAELHSVTRKLQEA 1251
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAE-----------------EKKKAEELKKAEEENKIKAAEEA 1667
PTZ00121 PTZ00121
MAEBL; Provisional
 806-1592 2.93e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.01  E-value: 2.93e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  806 TKLQEQLEEEARSA--GLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQE-----REAQRALESQALAHREALA 878
Cdd:PTZ00121  1082 DAKEDNRADEATEEafGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEdarkaEEARKAEDAKRVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  879 QLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEE 958
Cdd:PTZ00121  1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  959 LSRARRtlERVQQEAQSQQEQAQATISATTEELKALQAQFEDAI--TAHQRETTALRESLQ----DLAAERGDVEREAER 1032
Cdd:PTZ00121  1242 AKKAEE--ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkkAEEKKKADEAKKAEEkkkaDEAKKKAEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1033 LRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELR----ATICRAEQEKAS--FKRS 1106
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKkkadAAKKKAEEKKKAdeAKKK 1399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1107 KEEKEQKLLILEEAQAAlQQEASALRAHLWELEQAGgDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELR- 1185
Cdd:PTZ00121  1400 AEEDKKKADELKKAAAA-KKKADEAKKKAEEKKKAD-EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKk 1477

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1186 -----RQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQA 1260
Cdd:PTZ00121  1478 kaeeaKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL 1557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1261 RldqachrihsLEQELAQAEGARQDAEaqlgRLCSTLRRGLGLQRqspwASPEQPGSPTKGSDSSQALPGQQgtsppARP 1340
Cdd:PTZ00121  1558 K----------KAEEKKKAEEAKKAEE----DKNMALRKAEEAKK----AEEARIEEVMKLYEEEKKMKAEE-----AKK 1614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1341 HSPLRWPSPTPGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQsrvgqlqkalaEA 1420
Cdd:PTZ00121  1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK-----------KA 1683

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1421 EEGQRRVEgALSSARAARALQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQgkllEEQLTN 1500
Cdd:PTZ00121  1684 EEDEKKAA-EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD----EEEKKK 1758

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1501 LEHRCQKAEVSLEPLRQME----QETLKREEDVARLGAEKEQLDQSLNSLHQEVDGalRQNQQLQAQMTEMEQAHTQRLQ 1576
Cdd:PTZ00121  1759 IAHLKKEEEKKAEEIRKEKeaviEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGG--KEGNLVINDSKEMEDSAIKEVA 1836

                          810
                   ....*....|....*.
gi 1370478878 1577 DlTAQHQRDLATEAER 1592
Cdd:PTZ00121  1837 D-SKNMQLEEADAFEK 1851
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1067-1633 5.89e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 67.63  E-value: 5.89e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1067 EARRALSDEAREKDVLL----LFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAG 1142
Cdd:COG4913    239 RAHEALEDAREQIELLEpireLAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1143 GDARQELRELHRQVRTLKAEN----QRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEA 1218
Cdd:COG4913    319 DALREELDELEAQIRGNGGDRleqlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1219 HGQRLQEHLRESRGAEQTLRAELHSVTRKLQE----ASGVADALQARLDQACHRIHSLEQEL---------AQAEGARQD 1285
Cdd:COG4913    399 ELEALEEALAEAEAALRDLRRELRELEAEIASlerrKSNIPARLLALRDALAEALGLDEAELpfvgelievRPEEERWRG 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1286 A-EAQLGRLCSTL-------------------RRGLGLQRQSPWASPEQPGSPTKGSdssqaLPGQQGTSP-PARP--HS 1342
Cdd:COG4913    479 AiERVLGGFALTLlvppehyaaalrwvnrlhlRGRLVYERVRTGLPDPERPRLDPDS-----LAGKLDFKPhPFRAwlEA 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1343 PLrwpsptpgGRSSELMDVATVQDiLRDFVQ--------KLREAQRERDDSRI-------------QMATLSSRLSEAEC 1401
Cdd:COG4913    554 EL--------GRRFDYVCVDSPEE-LRRHPRaitragqvKGNGTRHEKDDRRRirsryvlgfdnraKLAALEAELAELEE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1402 RCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAAR--ALQKEALRRLElEHLASVRAAGQEKRRLQEQLETLRQALEE 1479
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELE-AELERLDASSDDLAALEEQLEELEAELEE 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1480 SRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQMEQETLKR--EEDVARLGAEkEQLDQSLNSLHQEVDGALRQN 1557
Cdd:COG4913    704 LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAllEERFAAALGD-AVERELRENLEERIDALRARL 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1558 QQLQAQMTEMEQAHTQRLQDLTAQHQRDLAT-----------EAERLHGARPQATQALESQEwthqqqvkvlEEQVASLK 1626
Cdd:COG4913    783 NRAEEELERAMRAFNREWPAETADLDADLESlpeylalldrlEEDGLPEYEERFKELLNENS----------IEFVADLL 852


                   ....*..
gi 1370478878 1627 EQLDQEV 1633
Cdd:COG4913    853 SKLRRAI 859
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 107-667 1.74e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 1.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  107 LAQASAERDELASRcrvvSEQLQARLETTEAQLRRSELEH---SVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKK 183
Cdd:COG1196    241 LEELEAELEELEAE----LEELEAELAELEAELEELRLELeelELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  184 ANDALGRELAGMTGSVQRLQGELELRRwAQRQTRSGGLGQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTA 263
Cdd:COG1196    317 RLEELEEELAELEEELEELEEELEELE-EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  264 RRLHTACLNLDSNL---------RLSASSTASTLGQQLRDKAGEMLQLQGRWDAEKVALQARLSEQTLLVEKLTEQNEQK 334
Cdd:COG1196    396 AELAAQLEELEEAEeallerlerLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  335 AKTIAALRTDLQNLVAQEDARcLELAGSSITELGEPRRPLRSPQRATSPHQGA---SPPHICSPATLDPALQAMRAAIER 411
Cdd:COG1196    476 EAALAELLEELAEAAARLLLL-LEAEADYEGFLEGVKAALLLAGLRGLAGAVAvliGVEAAYEAALEAALAAALQNIVVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  412 RWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKA 491
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  492 ALEMVVeELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVR 571
Cdd:COG1196    635 ALRRAV-TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  572 EALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQ----L 647
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVNLLAIEeyeeL 793

                          570       580
                   ....*....|....*....|
gi 1370478878  648 EQERDQLREQRKTLEQERAR 667
Cdd:COG1196    794 EERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 101-754 1.78e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 1.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  101 TRLGDLLAQASAERDELASRCRVVSE--QLQARLETTEAQLRRSELEH-SVDLEEALGRLEAAEERSTGLCQVNALLREQ 177
Cdd:COG1196    189 ERLEDILGELERQLEPLERQAEKAERyrELKEELKELEAELLLLKLRElEAELEELEAELEELEAELEELEAELAELEAE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  178 LEHMKKANDALGRELAGMTGSVQRLQGELElrRWAQRQTRsgglgqprdLLLLWRQAVVLGTDLAELRVATERGLADLQA 257
Cdd:COG1196    269 LEELRLELEELELELEEAQAEEYELLAELA--RLEQDIAR---------LEERRRELEERLEELEEELAELEEELEELEE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  258 DTARTARRLHTAclnldSNLRLSASSTASTLGQQLRDKAGEMLQLQGRWDAEKVALQARLSEQtllvEKLTEQNEQKAKT 337
Cdd:COG1196    338 ELEELEEELEEA-----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA----AELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  338 IAALRTDLQNLVAQEDARCLELAGSSITELGEprrplrspqratsphqgaspphicspatldpalqamRAAIERRWRREQ 417
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEE------------------------------------EEALEEAAEEEA 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  418 ELCLQLKSSQALVASLQEQLsesrrELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVV 497
Cdd:COG1196    453 ELEEEEEALLELLAELLEEA-----ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  498 EELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELaLRRERSCRAleTSQGRLQQLEEKVSGLREELASVREALSTA 577
Cdd:COG1196    528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY-LKAAKAGRA--TFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  578 QLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQ 657
Cdd:COG1196    605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  658 RKTLEQERARAGEQLAQAEQQLALERAERRGLQqacgRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQ 737
Cdd:COG1196    685 AERLAEEELELEEALLAEEEEERELAEAEEERL----EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                          650
                   ....*....|....*..
gi 1370478878  738 SLQDQEAQMGTLQQALQ 754
Cdd:COG1196    761 DLEELERELERLEREIE 777
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 676-1377 4.47e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 4.47e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  676 EQQLALERAERRG-----LQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQ 750
Cdd:pfam15921  244 EDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  751 QAL-QGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLesslleaQQLATKLQEQLEEEARSAGLARQALQVE 829
Cdd:pfam15921  324 STVsQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF-------SQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  830 MEQLQSDWEvQEMKLRQDTVRLQRQVAQQEREAQRAlesqalahrealaqlqrekETLSLTLAEEkevarCQLEQEKELV 909
Cdd:pfam15921  397 KEQNKRLWD-RDTGNSITIDHLRRELDDRNMEVQRL-------------------EALLKAMKSE-----CQGQMERQMA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  910 tksaaereALKGeiqslkqeRDESLLQLEHKMQQALSLKETERSLLsEELSRARRTLErvqqeaqsqqeQAQATISATTE 989
Cdd:pfam15921  452 --------AIQG--------KNESLEKVSSLTAQLESTKEMLRKVV-EELTAKKMTLE-----------SSERTVSDLTA 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  990 ELKalqaQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAqltvAQEGLAALRQELQGVEESREGLHREAQEAR 1069
Cdd:pfam15921  504 SLQ----EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRN----VQTECEALKLQMAEKDKVIEILRQQIENMT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1070 RALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQEL 1149
Cdd:pfam15921  576 QLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQER 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1150 RELHRQVRTLKAE-------------NQRRSGEAHE-------LQAQCSQEVLELRRQAAKAEAKHEG-ARKEVLGLQRK 1208
Cdd:pfam15921  656 DQLLNEVKTSRNElnslsedyevlkrNFRNKSEEMEtttnklkMQLKSAQSELEQTRNTLKSMEGSDGhAMKVAMGMQKQ 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1209 LAEVEA---AGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQD 1285
Cdd:pfam15921  736 ITAKRGqidALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1286 AEAQLGRLCSTLRRG------LGLQRQSPWASPEQPGSPTKGSDSSQALPgqqgTSPPARPHSPLRWPSPTPGGRSSELM 1359
Cdd:pfam15921  816 ASLQFAECQDIIQRQeqesvrLKLQHTLDVKELQGPGYTSNSSMKPRLLQ----PASFTRTHSNVPSSQSTASFLSHHSR 891

                          730
                   ....*....|....*....
gi 1370478878 1360 DVATV-QDILRDFVQKLRE 1377
Cdd:pfam15921  892 KTNALkEDPTRDLKQLLQE 910
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 652-1160 5.69e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.27  E-value: 5.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  652 DQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLE---QRQEQLEGQAALLGREKAQLQEQVgqvtcqk 728
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKkkiQKNKSLESQISELKKQNNQLKDNI------- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  729 qaleEQLAQSLQDQEAQMGTLQQAL-QGKDALSEERAQLLAKQEALERQGRLAAEEAADLrverdslesslleaQQLATK 807
Cdd:TIGR04523  235 ----EKKQQEINEKTTEISNTQTQLnQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQL--------------NQLKSE 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  808 LQEqleeearsagLARQALQVEMEQLQSDWEVQEMKLRQdtvrLQRQVAQQErEAQRALESQalahreaLAQLQREKETL 887
Cdd:TIGR04523  297 ISD----------LNNQKEQDWNKELKSELKNQEKKLEE----IQNQISQNN-KIISQLNEQ-------ISQLKKELTNS 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  888 SLTLAEEKEvarcQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQA------LSLKETERSLLSEELSR 961
Cdd:TIGR04523  355 ESENSEKQR----ELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNqqkdeqIKKLQQEKELLEKEIER 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  962 ARRTLErvqqeaqsqqeQAQATISATTEE----------LKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAE 1031
Cdd:TIGR04523  431 LKETII-----------KNNSEIKDLTNQdsvkeliiknLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1032 RLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALS---DEAREKDVLLLFN------SELRATICRAEQEKAS 1102
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISdleDELNKDDFELKKEnlekeiDEKNKEIEELKQTQKS 579

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878 1103 FKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLK 1160
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIK 637
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 504-721 5.70e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 63.24  E-value: 5.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  504 ADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDV 583
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  584 VESEREGLRSALA---RAECSNADLELLVRRLKSEGVEQ--------RDSLAAMAALMEGLAQDKSALNHLALQLEQERD 652
Cdd:COG4942     95 LRAELEAQKEELAellRALYRLGRQPPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  653 QLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQV 721
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
PTZ00121 PTZ00121
MAEBL; Provisional
 401-962 9.18e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 9.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCR 480
Cdd:PTZ00121  1196 AEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE 1275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  481 ASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAE----RREELALRRERSCRALETSQGRLQQL 556
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEeakkKADAAKKKAEEAKKAAEAAKAEAEAA 1355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  557 EEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADlellvrRLKSEGVEQRDSLAAMAALMEGLAQD 636
Cdd:PTZ00121  1356 ADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED------KKKADELKKAAAAKKKADEAKKKAEE 1429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  637 KSALNHLALQLEQERDQlrEQRKTLEQERARAGEQLAQAEQQLALERAERRGLQ-QACGRLEQRQEQLEGQAALLgREKA 715
Cdd:PTZ00121  1430 KKKADEAKKKAEEAKKA--DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEaKKADEAKKKAEEAKKKADEA-KKAA 1506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  716 QLQEQVGQVtcqKQALEEQLAQSLQDQEAQmgtlQQALQGKDALSEERAQLLAKQEALERqgrlaAEEAAdlRVERdsle 795
Cdd:PTZ00121  1507 EAKKKADEA---KKAEEAKKADEAKKAEEA----KKADEAKKAEEKKKADELKKAEELKK-----AEEKK--KAEE---- 1568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  796 sslleaqqlATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEvQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHRE 875
Cdd:PTZ00121  1569 ---------AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE-EEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  876 ALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAErEALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLL 955
Cdd:PTZ00121  1639 KKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE-EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717


                   ....*..
gi 1370478878  956 SEELSRA 962
Cdd:PTZ00121  1718 AEELKKA 1724
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
842-1293 1.79e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.01  E-value: 1.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  842 MKLRQDTVRLQRQV-----AQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVA-RCQLEQEKELVTKSAAE 915
Cdd:COG4913    238 ERAHEALEDAREQIellepIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEElRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  916 REALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQeaqsqqeqaqaTISATTEELKALQ 995
Cdd:COG4913    318 LDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL-----------PLPASAEEFAALR 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  996 AQfedaitahqrettaLRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDE 1075
Cdd:COG4913    387 AE--------------AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1076 AREKDVLLLFNSEL---------------------RATICRAEQEKASFKRSKEEKEQKLLI----LEEAQAALQQEASA 1130
Cdd:COG4913    453 LGLDEAELPFVGELievrpeeerwrgaiervlggfALTLLVPPEHYAAALRWVNRLHLRGRLvyerVRTGLPDPERPRLD 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1131 LRAHLWELEQAGGDARQELR-ELHRQVRTLKAENQ----------------RRSGEAHELQAQ---CSQEVL-------- 1182
Cdd:COG4913    533 PDSLAGKLDFKPHPFRAWLEaELGRRFDYVCVDSPeelrrhpraitragqvKGNGTRHEKDDRrriRSRYVLgfdnrakl 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1183 -ELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHgQRLQEHLRESRGAEQTLR--AELHSVTRKLQEASGVADALQ 1259
Cdd:COG4913    613 aALEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDVASAEReiAELEAELERLDASSDDLAALE 691

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1370478878 1260 ARLDQACHRIHSLEQELAQAEGARQDAEAQLGRL 1293
Cdd:COG4913    692 EQLEELEAELEELEEELDELKGEIGRLEKELEQA 725
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1374-1644 2.08e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 2.08e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1374 KLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEgalssaraaraLQKEALRRLELEHL 1453
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-----------LELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1454 ASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQMEQETLKREEDVARLG 1533
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1534 AEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALESQEWTHQQ 1613
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1370478878 1614 QVKVLEEQVASLKEQLDQEVQWRQQAHLGQA 1644
Cdd:COG1196    455 EEEEEALLELLAELLEEAALLEAALAELLEE 485
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
451-893 2.60e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 62.36  E-value: 2.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  451 QQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQrslllqaE 530
Cdd:PRK02224   284 LRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE-------E 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  531 RREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVR 610
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  611 RLKSEGVEQRDSLAA-----------MAALMEGLAQDKSALNhlalQLEQERDQLREQRKTLEQERARAgEQLAQAEQQL 679
Cdd:PRK02224   437 TARERVEEAEALLEAgkcpecgqpveGSPHVETIEEDRERVE----ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRI 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  680 ALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQ---LAQSLQDQEAQMGTLQQALQGK 756
Cdd:PRK02224   512 ERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEaeeAREEVAELNSKLAELKERIESL 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  757 DALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSaglarQALQVEMEQLQSD 836
Cdd:PRK02224   592 ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARE-----DKERAEEYLEQVE 666

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  837 WEVQEMKLRQDTVRLQRQVAQQEREAQRAL--ESQALAHR-EALAQLQREKETLSLTLAE 893
Cdd:PRK02224   667 EKLDELREERDDLQAEIGAVENELEELEELreRREALENRvEALEALYDEAEELESMYGD 726
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1368-1639 2.94e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 2.94e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1368 LRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRR 1447
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1448 LElehlASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEP----LRQMEQETL 1523
Cdd:COG1196    314 LE----ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEaeeeLEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1524 KREEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQA 1603
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1370478878 1604 LESQEWTHQQQVKVLEEQVASLKEQLDQEVQWRQQA 1639
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
646-1299 4.59e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 4.59e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLE------QERARAGEQLAQAEQQLA---LERAERRG--LQQACGRLEQRQEQLEGQAALLGREK 714
Cdd:COG4913    239 RAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAalrLWFAQRRLelLEAELEELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  715 AQLQEQVgqvtcqkQALEEQLAQSLQDQEAQmgtLQQALQGKDALSEERAQLLAKQEALerqgrlaaeeAADLRVERDSL 794
Cdd:COG4913    319 DALREEL-------DELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARLEAL----------LAALGLPLPAS 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  795 ESSLLEAQQLATKLQEQLEEEARSAglarqalqvemEQLQSDWEVQEMKLRQDTVRLQRQVAQQEReAQRALESQALAHR 874
Cdd:COG4913    379 AEEFAALRAEAAALLEALEEELEAL-----------EEALAEAEAALRDLRRELRELEAEIASLER-RKSNIPARLLALR 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  875 EALAQLQREKETLSLTLAEEKEVArcqleqEKELVTKSAAER----------------EALKGEIQSLKQERDESLLQLE 938
Cdd:COG4913    447 DALAEALGLDEAELPFVGELIEVR------PEEERWRGAIERvlggfaltllvppehyAAALRWVNRLHLRGRLVYERVR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  939 HKMQQALSLKETERSLLSE---ELSRARRTLERVQQEAQSQQEQaqatisATTEELKalqaQFEDAITAH-QRETTALRE 1014
Cdd:COG4913    521 TGLPDPERPRLDPDSLAGKldfKPHPFRAWLEAELGRRFDYVCV------DSPEELR----RHPRAITRAgQVKGNGTRH 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1015 SLQDLAAERG------DVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLllfnsE 1088
Cdd:COG4913    591 EKDDRRRIRSryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVA-----S 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1089 LRATICRAEQEKASFKRSKEEkeqkLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSG 1168
Cdd:COG4913    666 AEREIAELEAELERLDASSDD----LAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1169 EAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEahgQRLQEHLRESRGAEQTLRAELHSVTRKL 1248
Cdd:COG4913    742 LARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELE---RAMRAFNREWPAETADLDADLESLPEYL 818

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370478878 1249 QEASGVAD----ALQARLDQACHR--IHSLEQELAQAEGARQDAEAQLGRLCSTLRR 1299
Cdd:COG4913    819 ALLDRLEEdglpEYEERFKELLNEnsIEFVADLLSKLRRAIREIKERIDPLNDSLKR 875
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 644-865 1.12e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.01  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  644 ALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQ 723
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  724 VTCQKQALEEQLAQSLQD--QEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAA--EEAADLRVERDSLESSLL 799
Cdd:COG4942     95 LRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEElrADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370478878  800 EAQQLATKLQEQLeEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRA 865
Cdd:COG4942    175 ELEALLAELEEER-AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 516-1292 5.22e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 57.93  E-value: 5.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  516 AEAAELQRSLLLQAERREELALRRErscraletsqgrlqQLEEKVSGLREELASVREALSTAQLQRDVVESER------- 588
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDD--------------QWKEKRDELNGELSAADAAVAKDRSELEALEDQHgafldad 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  589 -EGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDksalnhLALQLEQERDQLREQRKTLEQERAR 667
Cdd:pfam12128  339 iETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQ------NNRDIAGIKDKLAKIREARDRQLAV 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  668 AGEQLAQAEQQLaleraeRRGLQQACGRLEQRQEQLEGQAallgrekAQLQEQVGQVTCQKQALeEQLAQSLQDQEAQMG 747
Cdd:pfam12128  413 AEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRL-------GELKLRLNQATATPELL-LQLENFDERIERARE 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  748 TLQQALQGKDALSEERAQL------------LAKQEALERQGRLAAEEA----------ADLRVE----RDSLESSLLEA 801
Cdd:pfam12128  479 EQEAANAEVERLQSELRQArkrrdqasealrQASRRLEERQSALDELELqlfpqagtllHFLRKEapdwEQSIGKVISPE 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  802 QQLATKLQEQLEEEARSAGLARQALQVEMEQLQ-SDWEVQEMKLRQDTVRLQRQVaQQEREAQRALESQALAHREALAQL 880
Cdd:pfam12128  559 LLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDvPEWAASEEELRERLDKAEEAL-QSAREKQAAAEEQLVQANGELEKA 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  881 QREkETLSLTLAEEKEVARCQL----EQEKELVTKSAAEREALKGE-IQSLKQErdesLLQLEHKMQQALSLKETERSLL 955
Cdd:pfam12128  638 SRE-ETFARTALKNARLDLRRLfdekQSEKDKKNKALAERKDSANErLNSLEAQ----LKQLDKKHQAWLEEQKEQKREA 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  956 SEELSRARRTLErvqqeaqsqqeqaqatiSATTEELKALQAQFEDAITAHQRETTALreslqdlaaergdvEREAERLRA 1035
Cdd:pfam12128  713 RTEKQAYWQVVE-----------------GALDAQLALLKAAIAARRSGAKAELKAL--------------ETWYKRDLA 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1036 QLTVAQEGLAALRQELQGVEESREGLHREAQEARRalsdearekdvlllFNSELRATIcraEQEKASFKRSKEEKEQKLL 1115
Cdd:pfam12128  762 SLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLR--------------YFDWYQETW---LQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1116 ILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLkaenQRRSGEAHELQ--AQCSQEVLELRRQAAKAEA 1193
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE----MSKLATLKEDAnsEQAQGSIGERLAQLEDLKL 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1194 KHEGARKEVLGLQRKLAEVEAAGEAHGqrLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLE 1273
Cdd:pfam12128  901 KRDYLSESVKKYVEHFKNVIADHSGSG--LAETWESLREEDHYQNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLREQV 978

                          810
                   ....*....|....*....
gi 1370478878 1274 QELAQAEGARQDAEAQLGR 1292
Cdd:pfam12128  979 SILGVDLTEFYDVLADFDR 997
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
769-1290 5.98e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 5.98e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  769 KQEALER-QGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQsdwEVQEmkLRQD 847
Cdd:PRK02224   185 QRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE---ELET--LEAE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  848 TVRLQRQVAQQEREaqralesqalahREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLK 927
Cdd:PRK02224   260 IEDLRETIAETERE------------REELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELR 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  928 QERDESLLQLEHKMQQALSLKETERSLLSE--ELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAH 1005
Cdd:PRK02224   328 DRLEECRVAAQAHNEEAESLREDADDLEERaeELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1006 QRettaLRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQEL---------QGVEESreGLHREAQEARRALSDEA 1076
Cdd:PRK02224   408 GN----AEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecgQPVEGS--PHVETIEEDRERVEELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1077 REKDVLLLFNSELRATICRAEQEKASFKR--------------------SKEEKEQKLLILEEAQAALQQEASALRAHLW 1136
Cdd:PRK02224   482 AELEDLEEEVEEVEERLERAEDLVEAEDRierleerredleeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1137 ELEQAGGDARQELRELHRQVRTLKAENQR--RSGEAHELQAQCSQEVLELR-RQAAKAEAKHEgaRKEVLGLQR-KLAEV 1212
Cdd:PRK02224   562 EAEEEAEEAREEVAELNSKLAELKERIESleRIRTLLAAIADAEDEIERLReKREALAELNDE--RRERLAEKReRKREL 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1213 EAA---------------GEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQArLDQACHRIHSLEQELA 1277
Cdd:PRK02224   640 EAEfdearieearedkerAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREA-LENRVEALEALYDEAE 718

                          570
                   ....*....|...
gi 1370478878 1278 QAEGARQDAEAQL 1290
Cdd:PRK02224   719 ELESMYGDLRAEL 731
mukB PRK04863
chromosome partition protein MukB;
418-1202 1.01e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 57.27  E-value: 1.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  418 ELCLQLKSSQALVASLQEQLSESRRELWAAQKlqqerareqarEREALRGQLE--AQRLEVQQCRAsckllGREKAALEm 495
Cdd:PRK04863   359 ELEERLEEQNEVVEEADEQQEENEARAEAAEE-----------EVDELKSQLAdyQQALDVQQTRA-----IQYQQAVQ- 421

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  496 VVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRrerscraLETSQGRLQQLEEKVSGLREELASV----- 570
Cdd:PRK04863   422 ALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQK-------LSVAQAAHSQFEQAYQLVRKIAGEVsrsea 494

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  571 ----REALSTAQLQRDVVESErEGLRSALARAEcsnadlellvRRLKsegvEQRDSLAAMAALMEGLAQDKSAlnhlALQ 646
Cdd:PRK04863   495 wdvaRELLRRLREQRHLAEQL-QQLRMRLSELE----------QRLR----QQQRAERLLAEFCKRLGKNLDD----EDE 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  647 LEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQacgrleQRQEQLEGQAALlgrekAQLQEQVGqvtc 726
Cdd:PRK04863   556 LEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAA------RAPAWLAAQDAL-----ARLREQSG---- 620

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  727 qkqaleeqlaQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQ-GRLAAEEAAD---LRVERDSLESSLLEAQ 802
Cdd:PRK04863   621 ----------EEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEiERLSQPGGSEdprLNALAERFGGVLLSEI 690

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  803 QLATKLQEQLEEEARsAGLARQALQVE-----MEQLQSDWEVQEMKL------------RQDTVRLQRQVAQQEREAQ-- 863
Cdd:PRK04863   691 YDDVSLEDAPYFSAL-YGPARHAIVVPdlsdaAEQLAGLEDCPEDLYliegdpdsfddsVFSVEELEKAVVVKIADRQwr 769

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  864 ----RALESQALAHREA-LAQLQREKETLSLTLAE-EKEVARCQ--LEQEKELVTKSAA-----EREALKGEIQSLKQER 930
Cdd:PRK04863   770 ysrfPEVPLFGRAAREKrIEQLRAEREELAERYATlSFDVQKLQrlHQAFSRFIGSHLAvafeaDPEAELRQLNRRRVEL 849

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  931 DESLLQLEHKMQQALSLKETERsllsEELSRARRTLERVQQEAQSQQEQAQATISA---TTEELKALQAQFEDAITAHQR 1007
Cdd:PRK04863   850 ERALADHESQEQQQRSQLEQAK----EGLSALNRLLPRLNLLADETLADRVEEIREqldEAEEAKRFVQQHGNALAQLEP 925

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1008 ETTALRESLQDLAAERGDVEREAERLRAqltvAQEGLAALRQELQGVEesreglHREAQEARRALSDEARekdvlllFNS 1087
Cdd:PRK04863   926 IVSVLQSDPEQFEQLKQDYQQAQQTQRD----AKQQAFALTEVVQRRA------HFSYEDAAEMLAKNSD-------LNE 988

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1088 ELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGD------------ARQELRELHRQ 1155
Cdd:PRK04863   989 KLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDlgvpadsgaeerARARRDELHAR 1068

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1370478878 1156 VRTlkaeNQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEV 1202
Cdd:PRK04863  1069 LSA----NRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQV 1111
mukB PRK04863
chromosome partition protein MukB;
510-1293 1.22e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.89  E-value: 1.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  510 EKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTA-QLQRDVVESER 588
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQeKIERYQADLEE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  589 EGLRSALARAECSNADLELLVRRLKSEGVEQR-DSLAA-MAALMEGL-AQDKSALN-HLALQLEQER-----------DQ 653
Cdd:PRK04863   360 LEERLEEQNEVVEEADEQQEENEARAEAAEEEvDELKSqLADYQQALdVQQTRAIQyQQAVQALERAkqlcglpdltaDN 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  654 LREQRKTLEQERARAGEQLAQAEQQLALERAERRglqqacgRLEQRQEQLEGQAALLGREKAQlqeQVGQVTCQKQALEE 733
Cdd:PRK04863   440 AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHS-------QFEQAYQLVRKIAGEVSRSEAW---DVARELLRRLREQR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  734 QLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLE 813
Cdd:PRK04863   510 HLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLE 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  814 E-EARSAGLARQA-----LQVEMEQLQS------DWEVQEMKLRQDTVRLQRQVAQQE---REAQRALESQA--LAHREA 876
Cdd:PRK04863   590 QlQARIQRLAARApawlaAQDALARLREqsgeefEDSQDVTEYMQQLLERERELTVERdelAARKQALDEEIerLSQPGG 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  877 --LAQLQREKETLS----------LTLAEEKEV------ARCQLeqekeLVTKSAAEREALKGE---------IQSLKQE 929
Cdd:PRK04863   670 seDPRLNALAERFGgvllseiyddVSLEDAPYFsalygpARHAI-----VVPDLSDAAEQLAGLedcpedlylIEGDPDS 744

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  930 RDESLLQLEhKMQQALSLKETERSLL-----SEEL--SRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAI 1002
Cdd:PRK04863   745 FDDSVFSVE-ELEKAVVVKIADRQWRysrfpEVPLfgRAAREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFI 823

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1003 TAHQreTTALR----ESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEarrALSDEARe 1078
Cdd:PRK04863   824 GSHL--AVAFEadpeAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADE---TLADRVE- 897

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1079 kdvlllfnsELRATICRAEQEKASFKRSKEEKEQklliLEEAQAALQQEASALRAhlweLEQAGGDARQELRELHRQVRT 1158
Cdd:PRK04863   898 ---------EIREQLDEAEEAKRFVQQHGNALAQ----LEPIVSVLQSDPEQFEQ----LKQDYQQAQQTQRDAKQQAFA 960

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1159 LKAENQRRS----GEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEveaageaHGQRLQEhLRESRGAE 1234
Cdd:PRK04863   961 LTEVVQRRAhfsyEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQ-------YNQVLAS-LKSSYDAK 1032

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370478878 1235 QTLRAELhsvTRKLQE-----ASGVADALQARLDQachrihsLEQELAQAEGARQDAEAQLGRL 1293
Cdd:PRK04863  1033 RQMLQEL---KQELQDlgvpaDSGAEERARARRDE-------LHARLSANRSRRNQLEKQLTFC 1086
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
401-857 2.20e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.08  E-value: 2.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIeRRWRREQELCL---QLKSSQALVASLQEQLSESRRELWAAQK----LQQERAREQAREREALRGQLEAQR 473
Cdd:COG4913    273 ELEYLRAAL-RLWFAQRRLELleaELEELRAELARLEAELERLEARLDALREeldeLEAQIRGNGGDRLEQLEREIERLE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  474 LEVQQCRascKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRL 553
Cdd:COG4913    352 RELEERE---RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEI 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  554 QQLEEKVSGLREELASVREALSTAQLQRDV----------VESEREGLRSALARAECSNAdLELLV-------------- 609
Cdd:COG4913    429 ASLERRKSNIPARLLALRDALAEALGLDEAelpfvgelieVRPEEERWRGAIERVLGGFA-LTLLVppehyaaalrwvnr 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  610 ----RRLKSEGVEQRDSLAAMAALMEG------LAQDKSALNHLALQLEQERD--------QLREQRKTLEQER------ 665
Cdd:COG4913    508 lhlrGRLVYERVRTGLPDPERPRLDPDslagklDFKPHPFRAWLEAELGRRFDyvcvdspeELRRHPRAITRAGqvkgng 587

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  666 ------------------ARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQ 727
Cdd:COG4913    588 trhekddrrrirsryvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAE 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  728 KQAleEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATK 807
Cdd:COG4913    668 REI--AELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|
gi 1370478878  808 LQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQ 857
Cdd:COG4913    746 ELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 605-1293 3.80e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 55.23  E-value: 3.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  605 LELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNhlaLQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLalERA 684
Cdd:pfam12128  253 LESAELRLSHLHFGYKSDETLIASRQEERQETSAELN---QLLRTLDDQWKEKRDELNGELSAADAAVAKDRSEL--EAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  685 ERRGLQQACGRLEQRqeqlegqaallgrekAQLQEQVGQVTCQKQALEEQLA---QSLQDQEAQMGTLQQA--LQGKDAL 759
Cdd:pfam12128  328 EDQHGAFLDADIETA---------------AADQEQLPSWQSELENLEERLKaltGKHQDVTAKYNRRRSKikEQNNRDI 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  760 SEERAQLLAKQEALERQgrLAAEEAADLRVE---RDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSD 836
Cdd:pfam12128  393 AGIKDKLAKIREARDRQ--LAVAEDDLQALEselREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  837 WEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALahrEALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAER 916
Cdd:pfam12128  471 ERIERAREEQEAANAEVERLQSELRQARKRRDQAS---EALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDW 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  917 EALKGEIQSlkqerDESLLQLEHKMQQALSLKETERSLLSEELSrarrtLERVQQEAQSqqeqaqatisATTEELKALQA 996
Cdd:pfam12128  548 EQSIGKVIS-----PELLHRTDLDPEVWDGSVGGELNLYGVKLD-----LKRIDVPEWA----------ASEEELRERLD 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  997 QFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAAL----RQELQGVEESREGLHREAQEARRAL 1072
Cdd:pfam12128  608 KAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLfdekQSEKDKKNKALAERKDSANERLNSL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1073 SDEAREKDV-LLLFNSELRATICRAEQEKASFKRS-KEEKEQKLLILEEAQAALQqeaSALRAHLWELEQ-------AGG 1143
Cdd:pfam12128  688 EAQLKQLDKkHQAWLEEQKEQKREARTEKQAYWQVvEGALDAQLALLKAAIAARR---SGAKAELKALETwykrdlaSLG 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1144 DARQELRELHRQVRTLKAENQRRSGEAHELQA--QCSQEVLELRRQAAKAEAkhEGARKEVLGLQRKLAEVEAAGEAHGQ 1221
Cdd:pfam12128  765 VDPDVIAKLKREIRTLERKIERIAVRRQEVLRyfDWYQETWLQRRPRLATQL--SNIERAISELQQQLARLIADTKLRRA 842

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370478878 1222 RLQEHLRESRGAEQTLRAEL---HSVTRKLQEASGVADALQARLdQACHRIHSLEQELAQAEGARQDAEAQLGRL 1293
Cdd:pfam12128  843 KLEMERKASEKQQVRLSENLrglRCEMSKLATLKEDANSEQAQG-SIGERLAQLEDLKLKRDYLSESVKKYVEHF 916
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 397-927 4.98e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.84  E-value: 4.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  397 TLDPALQAMRAAIE----RRWRREQELCLQLKSSQALVASLQEQLSESRRELWA-----------AQKLQQERAREQARE 461
Cdd:pfam12128  312 AADAAVAKDRSELEaledQHGAFLDADIETAAADQEQLPSWQSELENLEERLKAltgkhqdvtakYNRRRSKIKEQNNRD 391

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  462 REALRGQLEAQRLEVQQCRASCKllgrekAALEMVVEELKGKADAADAE----KQGLEAEAAELqRSLLLQAERREELAL 537
Cdd:pfam12128  392 IAGIKDKLAKIREARDRQLAVAE------DDLQALESELREQLEAGKLEfneeEYRLKSRLGEL-KLRLNQATATPELLL 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  538 RRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECS-NADLELLVRRLKSEG 616
Cdd:pfam12128  465 QLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlFPQAGTLLHFLRKEA 544

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  617 VEQRDSLAAMAA------------LMEGLAQDKSALNHLALQLEQ--------ERDQLREQRKTLEQERARAGEQLAQAE 676
Cdd:pfam12128  545 PDWEQSIGKVISpellhrtdldpeVWDGSVGGELNLYGVKLDLKRidvpewaaSEEELRERLDKAEEALQSAREKQAAAE 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  677 QQLALERAE-----------RRGLQQACGRL-----EQRQEQLEGQAAlLGREKAQLQEQVGQVTCQKQALEEQLAQSLQ 740
Cdd:pfam12128  625 EQLVQANGElekasreetfaRTALKNARLDLrrlfdEKQSEKDKKNKA-LAERKDSANERLNSLEAQLKQLDKKHQAWLE 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  741 DQEAQMGTLQQALQG----------------KDALSEERAQLLAKQEALERQGR--LAA-----EEAADLRVERDSLESS 797
Cdd:pfam12128  704 EQKEQKREARTEKQAywqvvegaldaqlallKAAIAARRSGAKAELKALETWYKrdLASlgvdpDVIAKLKREIRTLERK 783

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  798 LLEAQQLATKLQEQLEEEARSAGLARQALQV---EMEQLQSDWEVQEMKLRQDTvRLQRQVAQQEREAQRALESQALAHR 874
Cdd:pfam12128  784 IERIAVRRQEVLRYFDWYQETWLQRRPRLATqlsNIERAISELQQQLARLIADT-KLRRAKLEMERKASEKQQVRLSENL 862

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1370478878  875 EALAQLQREKETLSL--TLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLK 927
Cdd:pfam12128  863 RGLRCEMSKLATLKEdaNSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFK 917
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 398-678 7.54e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 7.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  398 LDPALQAMRAA---IERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAA-QKLQQERAREQAREREALRGQLEAQR 473
Cdd:TIGR02169  704 LDELSQELSDAsrkIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVkSELKELEARIEELEEDLHKLEEALND 783

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  474 LE-------VQQCRASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERR-------EELALRR 539
Cdd:TIGR02169  784 LEarlshsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksiekeiENLNGKK 863

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  540 ERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRS-------ALARAECSNADLELLVRRL 612
Cdd:TIGR02169  864 EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlselkaKLEALEEELSEIEDPKGED 943

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370478878  613 KSEgVEQRDSLAAMAALMEGLAQDKSAL---NHLALQ----LEQERDQLREQRKTLEQERARAGEQLAQAEQQ 678
Cdd:TIGR02169  944 EEI-PEEELSLEDVQAELQRVEEEIRALepvNMLAIQeyeeVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
651-1082 8.82e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 8.82e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  651 RDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQA 730
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  731 LEeqLAQSLQDQEAQMGTLQQALqgkDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQE 810
Cdd:COG4717    128 LP--LYQELEALEAELAELPERL---EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  811 QLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLT 890
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  891 LA----------EEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKE-------TERS 953
Cdd:COG4717    283 LGllallflllaREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQEllreaeeLEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  954 LLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRE--SLQDLAAERGDVEREAE 1031
Cdd:COG4717    363 LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELE 442

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1370478878 1032 RLRAQLTVAQEGLAALRQELQGVEESRE--GLHREAQEARRALSDEAREKDVL 1082
Cdd:COG4717    443 ELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWAAL 495
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
401-836 1.27e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  401 ALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELwaAQKLQQERAREQAREREALRGQLEAQRLEVQQCR 480
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL--EKLEKLLQLLPLYQELEALEAELAELPERLEELE 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  481 ASckllgrekaalEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERR-EELALRRERSCRALETSQGRLQQLEEK 559
Cdd:COG4717    153 ER-----------LEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEE 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  560 VSGLREELASVREALSTAQLQRdVVESEREGLRSALARAECSNADLELLVRRLKSEGVeQRDSLAAMAALMEGLAQDKSA 639
Cdd:COG4717    222 LEELEEELEQLENELEAAALEE-RLKEARLLLLIAAALLALLGLGGSLLSLILTIAGV-LFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  640 LNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQ------AALLG-- 711
Cdd:COG4717    300 LGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEeleqeiAALLAea 379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  712 --------REKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQqalqgKDALSEERAQLLAKQEALERQGRLAAEE 783
Cdd:COG4717    380 gvedeeelRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD-----EEELEEELEELEEELEELEEELEELREE 454

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  784 AADLRVERDSLESS-----LLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSD 836
Cdd:COG4717    455 LAELEAELEQLEEDgelaeLLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 76-589 1.37e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878   76 QAGVQEPTATVARVQEENELLQEELTRLGDLLAQASAERDELASRcrvvSEQLQARLETTEAQLRRSELEhsvdLEEALG 155
Cdd:COG1196    287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE----LEELEEELEELEEELEEAEEE----LEEAEA 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  156 RLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAGMTGSVQRLQGELElrrwAQRQTRSGGLGQPRDLLLLWRQAV 235
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE----ALLERLERLEEELEELEEALAELE 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  236 VLGTDLAELRVATERGLADLQADTARTARRLHTACLNLDSNLRLSASSTASTLGQQLRDKAGEMLQLQGRWDAEKVALQA 315
Cdd:COG1196    435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  316 RLSEQTLLVEKLTEQNEQKAKTIAALRTDLQNLVAQEDARCLELAGSSITELGEPRRPLRSPQRATSPHQGASPPHICSP 395
Cdd:COG1196    515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR 594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  396 ATLDPALQAmrAAIERRWRREQElclqlkssQALVASLQEQLSESRReLWAAQKLQQERAREQAREREALRGQLEAQRLE 475
Cdd:COG1196    595 GAIGAAVDL--VASDLREADARY--------YVLGDTLLGRTLVAAR-LEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  476 VQQCRAscKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQ 555
Cdd:COG1196    664 GGSRRE--LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL 741

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1370478878  556 LEEKVSGLREELASVREALSTAQLQRDVVESERE 589
Cdd:COG1196    742 LEEEELLEEEALEELPEPPDLEELERELERLERE 775
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 553-949 2.42e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 2.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  553 LQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEgveqrdslaamaalMEG 632
Cdd:TIGR04523  234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSE--------------ISD 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  633 LAQDKSA--LNHLALQLEQERDQLREQRKTL---EQERARAGEQLAQAEQQLALERAERRGLQQacgRLEQRQEQLEgqa 707
Cdd:TIGR04523  300 LNNQKEQdwNKELKSELKNQEKKLEEIQNQIsqnNKIISQLNEQISQLKKELTNSESENSEKQR---ELEEKQNEIE--- 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  708 aLLGREKAQLQEQVGQVTCQKQALEeqlaQSLQDQEAQMGTLQQALQGKDalsEERAQLLAKQEALERQGRLAAEEAADL 787
Cdd:TIGR04523  374 -KLKKENQSYKQEIKNLESQINDLE----SKIQNQEKLNQQKDEQIKKLQ---QEKELLEKEIERLKETIIKNNSEIKDL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  788 RVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDweVQEMK--------LRQDTVRLQRQVAQQE 859
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK--EKELKklneekkeLEEKVKDLTKKISSLK 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  860 rEAQRALESQALAHREALAQLQREKETLSLTLAE---EKEVARCQ--LEQEKELVTKSAAEREALKGEIQSLKQERDESL 934
Cdd:TIGR04523  524 -EKIEKLESEKKEKESKISDLEDELNKDDFELKKenlEKEIDEKNkeIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602

                          410
                   ....*....|....*
gi 1370478878  935 LQLEHKMQQALSLKE 949
Cdd:TIGR04523  603 KEIEEKEKKISSLEK 617
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 145-901 2.63e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 2.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  145 EHSVDLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKAN------DALGRELAGMTGSVqrLQGELELRRWAQRQTRS 218
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERekaeryQALLKEKREYEGYE--LLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  219 GGLGQPRDLLLLWRQAVVLGTDLAELRVATERGLADLQADTARTARRLHTACLNLDSNLRlSASSTASTLGQQLRDKAGE 298
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA-SLERSIAEKERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  299 MLQLQ---GRWDAEKVALQARLSEQTLLVEKLTEQNEQKAKTIAALRTDLQnlvaQEDARclelAGSSITELGEPRRPLR 375
Cdd:TIGR02169  324 LAKLEaeiDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE----EVDKE----FAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  376 SPQRATSPHQGASPPHICSPATLDPALQAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKLQ---- 451
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELydlk 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  452 ------QERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVEEL---------------KGKADAADAE 510
Cdd:TIGR02169  476 eeydrvEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLgsvgeryataievaaGNRLNNVVVE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  511 KQGLEAEAAELQRSllLQAERREELALRRERSCRaLETSQGRL--------------QQLEEKVS------GLREELASV 570
Cdd:TIGR02169  556 DDAVAKEAIELLKR--RKAGRATFLPLNKMRDER-RDLSILSEdgvigfavdlvefdPKYEPAFKyvfgdtLVVEDIEAA 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  571 REALSTAQ---LQRDVVesEREGLRSALARAECSnadLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQL 647
Cdd:TIGR02169  633 RRLMGKYRmvtLEGELF--EKSGAMTGGSRAPRG---GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  648 EQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTC- 726
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEAr 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  727 -------QKQALEEQLAQSLQDQEAQMGTLQQALQgkdALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLL 799
Cdd:TIGR02169  788 lshsripEIQAELSKLEEEVSRIEARLREIEQKLN---RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  800 EAQQLATKLQEQLEE-EARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQrqvaQQEREAQRALESQALAHREALa 878
Cdd:TIGR02169  865 ELEEELEELEAALRDlESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR----LSELKAKLEALEEELSEIEDP- 939

                          810       820
                   ....*....|....*....|...
gi 1370478878  879 qLQREKETLSLTLAEEKEVARCQ 901
Cdd:TIGR02169  940 -KGEDEEIPEEELSLEDVQAELQ 961
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 983-1204 2.63e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 2.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  983 TISATTEELKALQ---AQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESRE 1059
Cdd:COG4942     21 AAAEAEAELEQLQqeiAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1060 GLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELE 1139
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370478878 1140 QAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLG 1204
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 563-903 4.47e-06

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 51.59  E-value: 4.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  563 LREELASVREALSTAQLqrDVVESEREGLrSALARAECSNA----------DLELLVRRLKSEGVEQRDSLAAM------ 626
Cdd:PRK10929    28 ITQELEQAKAAKTPAQA--EIVEALQSAL-NWLEERKGSLErakqyqqvidNFPKLSAELRQQLNNERDEPRSVppnmst 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  627 AALMEGLAQDKSALNHLALQLEQERDQLRE---QRKTLEQERARAGEQLAQAEQQL--------ALERAERRGLQQACGR 695
Cdd:PRK10929   105 DALEQEILQVSSQLLEKSRQAQQEQDRAREisdSLSQLPQQQTEARRQLNEIERRLqtlgtpntPLAQAQLTALQAESAA 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  696 LEQRQEQLEgQAAL-------LGREKAQL-QEQVGQVTCQKQALEEQLaQSLQDQEAqmgtlQQALQGKDALSEERAQL- 766
Cdd:PRK10929   185 LKALVDELE-LAQLsannrqeLARLRSELaKKRSQQLDAYLQALRNQL-NSQRQREA-----ERALESTELLAEQSGDLp 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  767 --LAKQEALERQGRLAAEEAA---DLRVERDSLESS-LLEAQQLATKLQEQLE--------EEARSAGLAR-------QA 825
Cdd:PRK10929   258 ksIVAQFKINRELSQALNQQAqrmDLIASQQRQAASqTLQVRQALNTLREQSQwlgvsnalGEALRAQVARlpempkpQQ 337

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  826 LQVEMEQLQSD---WEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKeVARCQL 902
Cdd:PRK10929   338 LDTEMAQLRVQrlrYEDLLNKQPQLRQIRQADGQPLTAEQNRILDAQLRTQRELLNSLLSGGDTLILELTKLK-VANSQL 416


                   .
gi 1370478878  903 E 903
Cdd:PRK10929   417 E 417
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 619-825 4.52e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 4.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  619 QRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQ 698
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  699 RQEQLEGQAALLGREKAQLQEQ---------------------VGQVTCQKQALEEQLAQSLQDQEAQMGTLQQAlqgKD 757
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAE---RA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  758 ALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQA 825
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
866-1293 9.51e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 9.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  866 LESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLE-HKMQQA 944
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEkLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  945 LSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQAtISATTEELKALQAQFEDAItahQRETTALRESLQDLAAERG 1024
Cdd:COG4717    127 LLPLYQELEALEAELAELPERLEELEERLEELRELEEE-LEELEAELAELQEELEELL---EQLSLATEEELQDLAEELE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1025 DVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQ--EARRALSDEAREKDVLLLFNSELRATICRAEQEKAS 1102
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERlkEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1103 ----------FKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHE 1172
Cdd:COG4717    283 lgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1173 LQAQCSQEvlELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESR-----GAEQTLRAELHSVTRK 1247
Cdd:COG4717    363 LQLEELEQ--EIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEelleaLDEEELEEELEELEEE 440

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1370478878 1248 LQEASGVADALQARLDQACHRIHSLE--QELAQAEGARQDAEAQLGRL 1293
Cdd:COG4717    441 LEELEEELEELREELAELEAELEQLEedGELAELLQELEELKAELREL 488
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
602-1056 1.14e-05

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 50.35  E-value: 1.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  602 NADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLAL 681
Cdd:COG4995     10 LAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALAL 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  682 ERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSE 761
Cdd:COG4995     90 LAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAAAAALLALA 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  762 ERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQE 841
Cdd:COG4995    170 LALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAA 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  842 MKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKG 921
Cdd:COG4995    250 LAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLAALLLLLAA 329

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  922 EIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDA 1001
Cdd:COG4995    330 LALLALLLLLAAAALLAAALAAALALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALLALAAAQLL 409

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878 1002 ITAHQRETTALRESLQDLAAERGDVERE----AERLRAQLTVAQEGLAALRQELQGVEE 1056
Cdd:COG4995    410 RLLLAALALLLALAAYAAARLALLALIEyiilPDRLYAFVQLYQLLIAPIEAELPGIKR 468
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
529-1167 1.18e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.06  E-value: 1.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  529 AERREELALRRERscraLETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELL 608
Cdd:PRK03918   168 GEVIKEIKRRIER----LEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEEL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  609 VRRLKSegveqrdslaamaalmegLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERaERRG 688
Cdd:PRK03918   244 EKELES------------------LEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSE-FYEE 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  689 LQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEqLAQSLQDQEAQMGTLQQALQGKDALSEERA---- 764
Cdd:PRK03918   305 YLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKE-LEKRLEELEERHELYEEAKAKKEELERLKKrltg 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  765 ----QLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQE----------QLEEEARSAGLARQALqvEM 830
Cdd:PRK03918   384 ltpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrELTEEHRKELLEEYTA--EL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  831 EQLQSDWEVQEMKLRQDTVRLQrqvaqqEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVT 910
Cdd:PRK03918   462 KRIEKELKEIEEKERKLRKELR------ELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLI 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  911 KSAAEREALKGEIQSLKqERDESLLQLEHKMQqalSLKETERSLLSEELSRARRTLERVQqeaqsqqeqaqatisattEE 990
Cdd:PRK03918   536 KLKGEIKSLKKELEKLE-ELKKKLAELEKKLD---ELEEELAELLKELEELGFESVEELE------------------ER 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  991 LKALQAQFEDAITAHqrettalreslqdlaaergDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARR 1070
Cdd:PRK03918   594 LKELEPFYNEYLELK-------------------DAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK 654

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1071 ALSDEAREKDVLLLFnsELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASalrahlwELEQAgGDARQELR 1150
Cdd:PRK03918   655 KYSEEEYEELREEYL--ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK-------ELEKL-EKALERVE 724

                          650
                   ....*....|....*..
gi 1370478878 1151 ELHRQVRTLKAENQRRS 1167
Cdd:PRK03918   725 ELREKVKKYKALLKERA 741
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
618-1066 1.39e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 1.39e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  618 EQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAG--EQLAQAEQQLALERAERRGLQQACGR 695
Cdd:COG4717     78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELEERLEE 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  696 LEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQgkdALSEERAQLLAKQEALER 775
Cdd:COG4717    158 LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE---EAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  776 QGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQsdwevqemkLRQDTVRLQRQV 855
Cdd:COG4717    235 ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLL---------AREKASLGKEAE 305

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  856 AQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKElvtkSAAEREALKGEIQSLKQERDESLL 935
Cdd:COG4717    306 ELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE----ELEEELQLEELEQEIAALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  936 QLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRES 1015
Cdd:COG4717    382 EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1370478878 1016 LQDLAAER--GDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQ 1066
Cdd:COG4717    462 LEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 672-921 2.13e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  672 LAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQ 751
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  752 ALQGKDALSEERAQLLAKQEALERQGRLA----AEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSaglaRQALQ 827
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL----RAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  828 VEMEQLQsdwevqemklrqdtvrlqrQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKE 907
Cdd:COG4942    171 AERAELE-------------------ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                          250
                   ....*....|....
gi 1370478878  908 LVTKSAAEREALKG 921
Cdd:COG4942    232 LEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 524-781 2.28e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 2.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  524 SLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARaecsna 603
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE------ 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  604 dLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALER 683
Cdd:COG4942     88 -LEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  684 AErrglqqacgrLEQRQEQLEGQAALLGREKAQLQEQVGQvtcqKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEER 763
Cdd:COG4942    167 AE----------LEAERAELEALLAELEEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|....*...
gi 1370478878  764 AQLLAKQEALERQGRLAA 781
Cdd:COG4942    233 EAEAAAAAERTPAAGFAA 250
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
643-869 2.64e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.86  E-value: 2.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  643 LALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLqqacgrleqrqeQLEGQAALLGREKAQLQEQVG 722
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV------------DLSEEAKLLLQQLSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  723 QVTCQKQALEEQLAQsLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQ 802
Cdd:COG3206    230 EARAELAEAEARLAA-LRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  803 QLATKLQEQLEEEARSAGLARQALQVEMEQLQSdwEVQEM-KLRQDTVRLQRQVAQQEREAQRALESQ 869
Cdd:COG3206    309 QEAQRILASLEAELEALQAREASLQAQLAQLEA--RLAELpELEAELRRLEREVEVARELYESLLQRL 374
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
526-747 3.05e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.86  E-value: 3.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  526 LLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREA--LSTAQLQRDVVESEREGLRSALARAECSNA 603
Cdd:COG3206    157 LAEAYLEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  604 DLELLVRRLKSEGVEQRDSLAAMAALmEGLAQDKSALNHLALQLEQERDQLRE---QRKTLEQERARAGEQLAQAEQQLA 680
Cdd:COG3206    237 EAEARLAALRAQLGSGPDALPELLQS-PVIQQLRAQLAELEAELAELSARYTPnhpDVIALRAQIAALRAQLQQEAQRIL 315

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  681 LE-RAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTcQKQALEEQLAQSLQDQEAQMG 747
Cdd:COG3206    316 ASlEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVE-VARELYESLLQRLEEARLAEA 382
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
748-1211 3.53e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.61  E-value: 3.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  748 TLQQALQG--KDALSEERAQLLAKQEaleRQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEqLEEEARSAGLARQA 825
Cdd:COG4717     38 TLLAFIRAmlLERLEKEADELFKPQG---RKPELNLKELKELEEELKEAEEKEEEYAELQEELEE-LEEELEELEAELEE 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  826 LQVEMEQLQSDWEVQEmkLRQDTVRLQRQVAQQEREAQRaLESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQE 905
Cdd:COG4717    114 LREELEKLEKLLQLLP--LYQELEALEAELAELPERLEE-LEERLEELRELEEELEELEAELAELQEELEELLEQLSLAT 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  906 KELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSL-LSEELSRARRTL--ERVQQEAQSQQEQAQA 982
Cdd:COG4717    191 EEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAaLEERLKEARLLLliAAALLALLGLGGSLLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  983 TISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLh 1062
Cdd:COG4717    271 LILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEEL- 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1063 REAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLW-----E 1137
Cdd:COG4717    350 QELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEaldeeE 429

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370478878 1138 LEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAE 1211
Cdd:COG4717    430 LEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLE 503
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1006-1556 3.62e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 3.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1006 QRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARralsdearekdvlllf 1085
Cdd:PRK02224   198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIE---------------- 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1086 nsELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEA-------SALRAHLWELEQAGGDARQELRELHRQVRT 1158
Cdd:PRK02224   262 --DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglddadaEAVEARREELEDRDEELRDRLEECRVAAQA 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1159 LKAENQRRSGEAHELQAQCSqevlELRRQAAKAEAKHEGARKEVLGLQRKLAEVEA-----------------AGEAHGQ 1221
Cdd:PRK02224   340 HNEEAESLREDADDLEERAE----ELREEAAELESELEEAREAVEDRREEIEELEEeieelrerfgdapvdlgNAEDFLE 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1222 RLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQ--------------ARLDQACHRIHSLEQELAQAEGARQDAE 1287
Cdd:PRK02224   416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvETIEEDRERVEELEAELEDLEEEVEEVE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1288 AQLGRLCSTLRRGLGLQRqspwaspeqpgSPTKGSDSSQALPGQQGTSPPARPHSPlrwpspTPGGRSSELMDVATVQdi 1367
Cdd:PRK02224   496 ERLERAEDLVEAEDRIER-----------LEERREDLEELIAERRETIEEKRERAE------ELRERAAELEAEAEEK-- 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1368 lRDFVQKLREaqrERDDSRIQMATLSSRLSEAECRCARAQsRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEAL-- 1445
Cdd:PRK02224   557 -REAAAEAEE---EAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREALAELNDERRERLae 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1446 ---RRLELEHL---ASVRAAGQEKRRLQEQLETLRQALEEsrrhsqglakqgklLEEQLTNLEHRCQKAEVSLEPLRQME 1519
Cdd:PRK02224   632 kreRKRELEAEfdeARIEEAREDKERAEEYLEQVEEKLDE--------------LREERDDLQAEIGAVENELEELEELR 697

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1370478878 1520 QETLKREEDVARLGAEKEQLDQsLNSLHQEVDGALRQ 1556
Cdd:PRK02224   698 ERREALENRVEALEALYDEAEE-LESMYGDLRAELRQ 733
PTZ00121 PTZ00121
MAEBL; Provisional
 1051-1639 3.67e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.98  E-value: 3.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1051 LQGVEESREGLHREAQEARRALSDEarEKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILE--EAQAALQQEA 1128
Cdd:PTZ00121  1026 IEKIEELTEYGNNDDVLKEKDIIDE--DIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEatEEAFGKAEEA 1103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1129 SALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEA--KHEGARKevlglq 1206
Cdd:PTZ00121  1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEarKAEDAKK------ 1177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1207 rklaeVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDA 1286
Cdd:PTZ00121  1178 -----AEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE 1252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1287 EA---QLGRLCSTLRRGLGLQRQSPWASPE-------QPGSPTKGSDSSQALPGQQGTSPPARPHSPLRWPSPTPGGRSS 1356
Cdd:PTZ00121  1253 EIrkfEEARMAHFARRQAAIKAEEARKADElkkaeekKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD 1332

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1357 ELMDVAtvqdilrDFVQKLREAQRERDDSRIQMATLSSRLSEA-ECRCARAQSRVGQLQKALAE---AEEGQRRVEGALS 1432
Cdd:PTZ00121  1333 AAKKKA-------EEAKKAAEAAKAEAEAAADEAEAAEEKAEAaEKKKEEAKKKADAAKKKAEEkkkADEAKKKAEEDKK 1405

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1433 SARAARALQKEALRRLELEHLA-SVRAAGQEKRRLQE--QLETLRQALEESRRHSQGL--AKQGKLLEE---------QL 1498
Cdd:PTZ00121  1406 KADELKKAAAAKKKADEAKKKAeEKKKADEAKKKAEEakKADEAKKKAEEAKKAEEAKkkAEEAKKADEakkkaeeakKA 1485

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1499 TNLEHRCQKAEVSLEPLRQMEQETLKREEdvARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQaQMTEMEQAHTQRLQDL 1578
Cdd:PTZ00121  1486 DEAKKKAEEAKKKADEAKKAAEAKKKADE--AKKAEEAKKADEAKKAEEAKKADEAKKAEEKK-KADELKKAEELKKAEE 1562

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878 1579 TAQHQRDLATEAERLHGARpQATQALESQEWTHQQQVKVLEEQVASLKEQLDQEVQWRQQA 1639
Cdd:PTZ00121  1563 KKKAEEAKKAEEDKNMALR-KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 403-1083 3.82e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 3.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  403 QAMRAAIERRWRREQELCLQLKSSQALVASLQEQLSESRRELWAAQKLQQERAREQAREREALRGQLEAQRlEVQQCRAS 482
Cdd:TIGR00618  190 KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ-LLKQLRAR 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  483 CKLLGREKAALEMVVEELKGKADAAdaekqgleaeaaelqrSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSG 562
Cdd:TIGR00618  269 IEELRAQEAVLEETQERINRARKAA----------------PLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  563 LREELASVREA-LSTAQLQRDVVESEREGLRSALARAE-CSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSAL 640
Cdd:TIGR00618  333 HVKQQSSIEEQrRLLQTLHSQEIHIRDAHEVATSIREIsCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATI 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 NHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEq 720
Cdd:TIGR00618  413 DTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAV- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  721 VGQVTCQKQALEEQLAQSLQDQEAQMgtlqQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLE 800
Cdd:TIGR00618  492 VLARLLELQEEPCPLCGSCIHPNPAR----QDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQE 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  801 AQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEvQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQL 880
Cdd:TIGR00618  568 IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSE-AEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLT 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  881 QREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERdESLLQLEHKMQQALSlKETERSLLSEELS 960
Cdd:TIGR00618  647 ALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWK-EMLAQCQTLLRELET-HIEEYDREFNEIE 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  961 RARRTLERVQQEAQSQQEQAQATISATTEElkALQAQFEDAITAHQRETTALrESLQDLAAERGDVEREAERLRAQLTVA 1040
Cdd:TIGR00618  725 NASSSLGSDLAAREDALNQSLKELMHQART--VLKARTEAHFNNNEEVTAAL-QTGAELSHLAAEIQFFNRLREEDTHLL 801

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 1370478878 1041 QEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLL 1083
Cdd:TIGR00618  802 KTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATL 844
PTZ00121 PTZ00121
MAEBL; Provisional
 1008-1632 3.96e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 3.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1008 ETTALRESLQDLAAErgDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLH-REAQEARRAlsDEARekdvlllfn 1086
Cdd:PTZ00121  1080 DFDAKEDNRADEATE--EAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEaRKAEDARKA--EEAR--------- 1146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1087 selraticRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEAsALRAHlwELEQAggdarQELR---ELHRQVRTLKAEN 1163
Cdd:PTZ00121  1147 --------KAEDAKRVEIARKAEDARKAEEARKAEDAKKAEA-ARKAE--EVRKA-----EELRkaeDARKAEAARKAEE 1210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1164 QRRSGEAHelQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLR--ESRGAEQTLRAEL 1241
Cdd:PTZ00121  1211 ERKAEEAR--KAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKaeEARKADELKKAEE 1288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1242 HSVTRKLQEASGVADALQARldqachrihSLEQELAQAEGARQDAEAQLGRLCSTLRRGLGLQRQSPWASPEQPGSPTKG 1321
Cdd:PTZ00121  1289 KKKADEAKKAEEKKKADEAK---------KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA 1359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1322 SDSSQALPGQQGTSPPARPHSPLRWPSPTPGGRSSELMDVATVQDILRDFVQKLREAQRERDDSRiqmatlssRLSEAEC 1401
Cdd:PTZ00121  1360 EAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK--------KKAEEKK 1431

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1402 RCARAQSRVGQLQKAlaeaEEGQRRVEgalsSARAARALQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEESR 1481
Cdd:PTZ00121  1432 KADEAKKKAEEAKKA----DEAKKKAE----EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAK 1503

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1482 RHSQGLAKQGKLLEEQLTNLEHRCQKAEVS--LEPLRQMEQ----ETLKREEDVaRLGAEKEQLDQSLNSlHQEVDGALR 1555
Cdd:PTZ00121  1504 KAAEAKKKADEAKKAEEAKKADEAKKAEEAkkADEAKKAEEkkkaDELKKAEEL-KKAEEKKKAEEAKKA-EEDKNMALR 1581

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878 1556 QNQQLQaqmtEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALESQEWTHQ-QQVKVLEEQVASLKEQLDQE 1632
Cdd:PTZ00121  1582 KAEEAK----KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKvEQLKKKEAEEKKKAEELKKA 1655
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 842-958 4.68e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 48.15  E-value: 4.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  842 MKLRQDTV-----RLQRQVAQQEREAQRALESQALAHREALAQLQREKEtlslTLAEEKEVARCQLEQEKELVTKSAAER 916
Cdd:COG0542    402 VRMEIDSKpeeldELERRLEQLEIEKEALKKEQDEASFERLAELRDELA----ELEEELEALKARWEAEKELIEEIQELK 477

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1370478878  917 EALkgeiqslkQERDESLLQLEHKMQQALSLKETERSLLSEE 958
Cdd:COG0542    478 EEL--------EQRYGKIPELEKELAELEEELAELAPLLREE 511
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 489-1293 4.74e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 4.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  489 EKAALEMVVEELKGKADAADAEKQ--GLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREE 566
Cdd:pfam01576  200 EKGRQELEKAKRKLEGESTDLQEQiaELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQED 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  567 LASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQD-----KSALN 641
Cdd:pfam01576  280 LESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEmrqkhTQALE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  642 HLALQLEQE---RDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQ 718
Cdd:pfam01576  360 ELTEQLEQAkrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQ 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  719 EQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSL 798
Cdd:pfam01576  440 SELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQL 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  799 LEAQQLATKLQEQLEEEARSAGL---ARQALQVEMEQLQSDWEVQEM---KLRQDTVRLQRQV--AQQEREAQRALESQA 870
Cdd:pfam01576  520 STLQAQLSDMKKKLEEDAGTLEAleeGKKRLQRELEALTQQLEEKAAaydKLEKTKNRLQQELddLLVDLDHQRQLVSNL 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  871 LAHREALAQLQREKETLSLTLAEEKEVARCQlEQEKElvTKSAAEREALKgEIQSLKQERDESLLQLEHKMQQALSLKEt 950
Cdd:pfam01576  600 EKKQKKFDQMLAEEKAISARYAEERDRAEAE-AREKE--TRALSLARALE-EALEAKEELERTNKQLRAEMEDLVSSKD- 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  951 ERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTE-------ELKALQAQFEDAITAH----QRETTALRESLQDL 1019
Cdd:pfam01576  675 DVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDaklrlevNMQALKAQFERDLQARdeqgEEKRRQLVKQVREL 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1020 AAERGD--------------VEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSD---EAREKDVL 1082
Cdd:pfam01576  755 EAELEDerkqraqavaakkkLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEilaQSKESEKK 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1083 LlfnSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAE 1162
Cdd:pfam01576  835 L---KNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDR 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1163 NQRRSGEAHELQAQCSQEvlelRRQAAKAEAKHEGARKEVLGLQRKLAEVE-----------AAGEAHGQRLQEHL---- 1227
Cdd:pfam01576  912 LRKSTLQVEQLTTELAAE----RSTSQKSESARQQLERQNKELKAKLQEMEgtvkskfkssiAALEAKIAQLEEQLeqes 987

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878 1228 RESRGAEQTLR---AELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRL 1293
Cdd:pfam01576  988 RERQAANKLVRrteKKLKEVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKL 1056
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 325-957 5.22e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 5.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  325 EKLTEQNEQKAKTIAALRTDLQNLVAQEDARCLELagssitELGEPRRPLRSPQRATSPHQGASPPHICSPATLDPALQA 404
Cdd:TIGR00618  238 TQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEEL------RAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  405 MRAAIERRWRREQELCLQLKSSQALVASLQEQlsesrRELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRAsck 484
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQ-----RRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHT--- 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  485 lLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQ--RSLLLQAERREELALRRERSCRALETSQgrLQQLEEKVSG 562
Cdd:TIGR00618  384 -LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlQGQLAHAKKQQELQQRYAELCAAAITCT--AQCEKLEKIH 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  563 LREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSL--AAMAALMEGLAQDKSAL 640
Cdd:TIGR00618  461 LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDnpGPLTRRMQRGEQTYAQL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 NHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQR-QEQLEGQAALLGREKAQLQE 719
Cdd:TIGR00618  541 ETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLtEKLSEAEDMLACEQHALLRK 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  720 QVGQVTCQKQALEE-QLAQSLQDQEAQMGTLQQALQGKDAlsEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSL 798
Cdd:TIGR00618  621 LQPEQDLQDVRLHLqQCSQELALKLTALHALQLTLTQERV--REHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEM 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  799 LEAQQLATKLQEQLEEEARSaglarqalqvEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALA 878
Cdd:TIGR00618  699 LAQCQTLLRELETHIEEYDR----------EFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNE 768

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  879 QLQREKETLSlTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSE 957
Cdd:TIGR00618  769 EVTAALQTGA-ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGE 846
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 552-1195 5.83e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.04  E-value: 5.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  552 RLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSA-LARAECSNADLELLVRRLKSEGVEQRDSLAAMAALM 630
Cdd:TIGR00618  220 RKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  631 EglaqdksALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQaEQQLALERAERRGLQQACGRLEQRQEQLEGQAALL 710
Cdd:TIGR00618  300 K-------AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQ-QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIS 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  711 grekaqlqeqvgqvtCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAK-QEALERQGRLAAEEAAdlrv 789
Cdd:TIGR00618  372 ---------------CQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRtSAFRDLQGQLAHAKKQ---- 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  790 ERDSLESSLLEAQQLATKLQEQLEEEaRSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQE-------REA 862
Cdd:TIGR00618  433 QELQQRYAELCAAAITCTAQCEKLEK-IHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEepcplcgSCI 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  863 QRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDES------LLQ 936
Cdd:TIGR00618  512 HPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSkedipnLQN 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  937 LEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESL 1016
Cdd:TIGR00618  592 ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1017 QDLAAERGDVEREAERLRAQLTVAQEGLA----ALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRat 1092
Cdd:TIGR00618  672 KELLASRQLALQKMQSEKEQLTYWKEMLAqcqtLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM-- 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1093 icraEQEKASFKRSKEEKEQKLLILEEAQAALQQEAsalrahlwELEQAGGDARQELRELHRQVRTLKAE-NQRRSGEAH 1171
Cdd:TIGR00618  750 ----HQARTVLKARTEAHFNNNEEVTAALQTGAELS--------HLAAEIQFFNRLREEDTHLLKTLEAEiGQEIPSDED 817

                          650       660
                   ....*....|....*....|....
gi 1370478878 1172 ELQAQCSQEVLELRRQAAKAEAKH 1195
Cdd:TIGR00618  818 ILNLQCETLVQEEEQFLSRLEEKS 841
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 419-667 6.20e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  419 LCLQLKSSQALVASLQEQLSESRRELwaaqKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVE 498
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEI----AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  499 ELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETsqgRLQQLEEKVSGLREELASVREALSTAQ 578
Cdd:COG4942     87 ELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVR---RLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  579 LQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQR 658
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ....*....
gi 1370478878  659 KTLEQERAR 667
Cdd:COG4942    244 PAAGFAALK 252
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 852-1293 8.66e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 8.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  852 QRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAER--EALKGEIQSLKQE 929
Cdd:pfam12128  208 DDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETliASRQEERQETSAE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  930 RDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEdaitahqret 1009
Cdd:pfam12128  288 LNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELE---------- 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1010 tALRESLQDLAAERGDVEREAERLRAQltVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREkdvlllFNSEL 1089
Cdd:pfam12128  358 -NLEERLKALTGKHQDVTAKYNRRRSK--IKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESE------LREQL 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1090 RATICRAEQEKASFK-RSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQE-LRELHRQVRTLKAENQRRS 1167
Cdd:pfam12128  429 EAGKLEFNEEEYRLKsRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVErLQSELRQARKRRDQASEAL 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1168 GEAHELQAQCSQEVLELRRQ-AAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGA------------- 1233
Cdd:pfam12128  509 RQASRRLEERQSALDELELQlFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGgelnlygvkldlk 588

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1234 ----------EQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRL 1293
Cdd:pfam12128  589 ridvpewaasEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRL 658
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
875-1299 8.81e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 8.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  875 EALAQLQREKETLSLTLAEEKEVARCQLEQEKELvtksaaerEALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSL 954
Cdd:PRK03918   169 EVIKEIKRRIERLEKFIKRTENIEELIKEKEKEL--------EEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  955 lsEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFED--AITAHQRETTALRESLQDLAAERGDVEREAER 1032
Cdd:PRK03918   241 --EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKElkELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1033 LRAQLTVAQEGLaalrQELQGVEESREGLHREAQEARRALsdEAREKDVLLLfnSELRATICRAEQEKASFK-RSKEEKE 1111
Cdd:PRK03918   319 LEEEINGIEERI----KELEEKEERLEELKKKLKELEKRL--EELEERHELY--EEAKAKKEELERLKKRLTgLTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1112 QKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENqRRSGEAH--ELQAQCSQEVLELRRQAA 1189
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG-RELTEEHrkELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1190 KAEAKHEGARKEVLGLQRKLAEveaagEAHGQRLQEHLRESRGAEQTLRA----ELHSVTRKLQEASGVADALQAR---L 1262
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKK-----ESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEiksL 544

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1370478878 1263 DQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRR 1299
Cdd:PRK03918   545 KKELEKLEELKKKLAELEKKLDELEEELAELLKELEE 581
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 554-1290 1.16e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  554 QQLEEKVSGLREELASVREALSTAQLQRDVVESEREGL---RSALARAECSNADLELLVRrlksEGVEQRDSLAAMAALM 630
Cdd:COG3096    281 RELSERALELRRELFGARRQLAEEQYRLVEMARELEELsarESDLEQDYQAASDHLNLVQ----TALRQQEKIERYQEDL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  631 EGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQqlALERAERRGLQ--QACGRLEQRQEQL----- 703
Cdd:COG3096    357 EELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQ--ALDVQQTRAIQyqQAVQALEKARALCglpdl 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  704 --EGQAALLGREKAQLQEQVGQVTcqkqaleeQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALE-----RQ 776
Cdd:COG3096    435 tpENAEDYLAAFRAKEQQATEEVL--------ELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTAREllrryRS 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  777 GRLAAEEAADLRVERDSLESsLLEAQQLATKLQEQLEEeaRSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVA 856
Cdd:COG3096    507 QQALAQRLQQLRAQLAELEQ-RLRQQQNAERLLEEFCQ--RIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSEL 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  857 QQEREA----QRALESQALAHREALAQLQREKETLSLTLAEEKEVARC---QLEQEKELVT---KSAAEREALKGEIQSL 926
Cdd:COG3096    584 RQQLEQlrarIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAmqqLLEREREATVerdELAARKQALESQIERL 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  927 KQ---ERDESLLQL-EHKMQQALSLKETERSL-----LSEELSRARRTLervqqeaqsqqeqAQATISATTEELKALQAQ 997
Cdd:COG3096    664 SQpggAEDPRLLALaERLGGVLLSEIYDDVTLedapyFSALYGPARHAI-------------VVPDLSAVKEQLAGLEDC 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  998 FEDaITAHQRETTALRESLQDLAA-ERGDVEREAERlraQL------TVAQEGLAALRQELQGVEESREGLHREAQEARR 1070
Cdd:COG3096    731 PED-LYLIEGDPDSFDDSVFDAEElEDAVVVKLSDR---QWrysrfpEVPLFGRAAREKRLEELRAERDELAEQYAKASF 806

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1071 ALSDEAREKDVLLLFNSELRATICRA--EQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLweleqaggdarQE 1148
Cdd:COG3096    807 DVQKLQRLHQAFSQFVGGHLAVAFAPdpEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQL-----------QL 875

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1149 LRELHRQVRTLKAEN-QRRSGEAHELQAQCSQEVLELRRQAAKAEAkhegarkevlgLQRKLAEVEAAGEAHGQrLQEHL 1227
Cdd:COG3096    876 LNKLLPQANLLADETlADRLEELREELDAAQEAQAFIQQHGKALAQ-----------LEPLVAVLQSDPEQFEQ-LQADY 943

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370478878 1228 RESRGAEQTLRAELHSVTRKLQ--EASGVADAlQARLDQACHRIHSLEQELAQAEGARQDAEAQL 1290
Cdd:COG3096    944 LQAKEQQRRLKQQIFALSEVVQrrPHFSYEDA-VGLLGENSDLNEKLRARLEQAEEARREAREQL 1007
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 843-1071 1.82e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  843 KLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELvTKSAAEREALKGE 922
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL-AELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  923 IQSLKQERDESLLQLeHKMQQALSLKETERSLLSEELSRARRTLERVqqeaQSQQEQAQATISATTEELKALQAQFEDAI 1002
Cdd:COG4942     99 LEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYL----APARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878 1003 TAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRA 1071
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
646-967 2.43e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 45.28  E-value: 2.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVT 725
Cdd:COG4372     49 QLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLE 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  726 CQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLA 805
Cdd:COG4372    129 QQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKL 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  806 TKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKE 885
Cdd:COG4372    209 IESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEAL 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  886 TLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRT 965
Cdd:COG4372    289 EEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVA 368


                   ..
gi 1370478878  966 LE 967
Cdd:COG4372    369 DG 370
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1042-1629 2.66e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.98  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1042 EGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLL-FNSELRaticraeQEKASFKRSKEEKEQKLLILEEA 1120
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAeLNQLLR-------TLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1121 QAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTlKAENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGAR- 1199
Cdd:pfam12128  317 VAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQS-ELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGi 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1200 KEVLGLQRKLAEVE-AAGEAHGQRLQEHLRESRGA------EQTLRAELHSVTRKLQEASGVA---------------DA 1257
Cdd:pfam12128  396 KDKLAKIREARDRQlAVAEDDLQALESELREQLEAgklefnEEEYRLKSRLGELKLRLNQATAtpelllqlenfderiER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1258 LQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLrrglgLQRQSPWASPEQPGSPTKGSdssqaLPGQQGTSPP 1337
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRL-----EERQSALDELELQLFPQAGT-----LLHFLRKEAP 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1338 ARPHSPLRWPSPTPGGRSS--ELMDVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQK 1415
Cdd:pfam12128  546 DWEQSIGKVISPELLHRTDldPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1416 ALAEAEEGQRRVEGALSSARAARALQKEALRRLELEHlasvraaGQEKRRLQEQLETLRQALEESRRHsqgLAKQGKLLE 1495
Cdd:pfam12128  626 QLVQANGELEKASREETFARTALKNARLDLRRLFDEK-------QSEKDKKNKALAERKDSANERLNS---LEAQLKQLD 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1496 eqltnLEHRCQKAEVSLEPLRQMEQETLKREEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQRL 1575
Cdd:pfam12128  696 -----KKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVI 770

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370478878 1576 QDLtAQHQRDLATEAERLHGARPQATQALESQEWTHQQQVKVLEEQVASLKEQL 1629
Cdd:pfam12128  771 AKL-KREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAI 823
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 760-1251 2.76e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.73  E-value: 2.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  760 SEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEV 839
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQS 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  840 QEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKEtlsltlaEEKEVARCQLEQEKelVTKSAAEREAL 919
Cdd:TIGR00618  242 HAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERIN-------RARKAAPLAAHIKA--VTQIEQQAQRI 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  920 KGEIQSLKQERDESLLQLEHKMQQALSLKETERS---LLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQA 996
Cdd:TIGR00618  313 HTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLlqtLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLT 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  997 QFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEa 1076
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKER- 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1077 rekdvllLFNSELRATICRAEQEKasfkrsKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQV 1156
Cdd:TIGR00618  472 -------EQQLQTKEQIHLQETRK------KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1157 RTLKA-ENQRRSGEAHELQAQCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAeveaageahgQRLQEHLRESRGAEQ 1235
Cdd:TIGR00618  539 QLETSeEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT----------VRLQDLTEKLSEAED 608

                          490
                   ....*....|....*.
gi 1370478878 1236 TLRAELHSVTRKLQEA 1251
Cdd:TIGR00618  609 MLACEQHALLRKLQPE 624
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 800-1569 3.25e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 45.73  E-value: 3.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  800 EAQQLATKLQEQLEEEARSAGLARQAlQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQ 879
Cdd:pfam02463  181 ETENLAELIIDLEELKLQELKLKEQA-KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  880 LQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEel 959
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI-- 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  960 srarrtlervqqeaqsqqeqaqatisattEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTV 1039
Cdd:pfam02463  338 -----------------------------EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1040 AQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEE 1119
Cdd:pfam02463  389 AAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1120 AQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELqaqCSQEVLELRRQAAKAEAKHEGAR 1199
Cdd:pfam02463  469 KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG---RIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1200 KEVLGLQRKLAEVEAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADALQARLDQACHRIHSLEQELAQA 1279
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1280 EGARQDAEaQLGRLCSTLRRGLGLQRQSPWASPEQPGSPTKGSDSSQALPGQQgtspparphsplrwpSPTPGGRSSELM 1359
Cdd:pfam02463  626 EGILKDTE-LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLE---------------IQELQEKAESEL 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1360 DVATVQDILRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARA 1439
Cdd:pfam02463  690 AKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1440 LQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQME 1519
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1520 QETLKREEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQ 1569
Cdd:pfam02463  850 KLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEK 899
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 646-1056 3.60e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 3.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAqaEQQLALERAERRGLQqacgrLEQRQEQLEGQAALLGREKAQ-----LQEQ 720
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQNKIKKQLS--EKQKELEQNNKKIKE-----LEKQLNQLKSEISDLNNQKEQdwnkeLKSE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  721 VGQVTCQKQALEEQLAQSLQ---DQEAQMGTLQQALQGKDAL-SEERAQLLAKQ---EALERQGRLAAEEAADLRVERDS 793
Cdd:TIGR04523  316 LKNQEKKLEEIQNQISQNNKiisQLNEQISQLKKELTNSESEnSEKQRELEEKQneiEKLKKENQSYKQEIKNLESQIND 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  794 LESSLLEAQQLATKLQEQLEEearsaglarqaLQVEMEQLQSDWEvqemKLRQDTVRLQRQVAQQEREaQRALESQALAH 873
Cdd:TIGR04523  396 LESKIQNQEKLNQQKDEQIKK-----------LQQEKELLEKEIE----RLKETIIKNNSEIKDLTNQ-DSVKELIIKNL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  874 REALAQLQREKETLSLTLAEEKEvarcQLEQ-EKELVTKSA------AEREALKGEIQSLKQERDESLLQLE----HKMQ 942
Cdd:TIGR04523  460 DNTRESLETQLKVLSRSINKIKQ----NLEQkQKELKSKEKelkklnEEKKELEEKVKDLTKKISSLKEKIEklesEKKE 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  943 QALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATIS---ATTEELKALQAQFEDAITAHQRETTALRESLQDL 1019
Cdd:TIGR04523  536 KESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKslkKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL 615

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1370478878 1020 AAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEE 1056
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1450-1639 4.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1450 LEHLASVRAAGQEKRRLQEQLETLRQALEESRRHsQGLAKQGKLLEEQLTNLEHRCQKAEVSL--EPLRQMEQETLKREE 1527
Cdd:COG4913    231 VEHFDDLERAHEALEDAREQIELLEPIRELAERY-AAARERLAELEYLRAALRLWFAQRRLELleAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1528 DVARLGAEKEQLDQSLNSLHQEVDGA-LRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRdlateAERLHGARPQATQALES 1606
Cdd:COG4913    310 ELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEAL-----LAALGLPLPASAEEFAA 384

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1370478878 1607 QEWTHQQQVKVLEEQVASLKEQLDQEVQWRQQA 1639
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAALRDL 417
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 683-1535 5.02e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 5.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  683 RAERRGLQQACgrLEQRQEQLEGQAALLgREKAQLQEQVGQVTcQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEE 762
Cdd:COG3096    277 ANERRELSERA--LELRRELFGARRQLA-EEQYRLVEMARELE-ELSARESDLEQDYQAASDHLNLVQTALRQQEKIERY 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  763 RAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKL---QEQLEEEARSAGLARQALQVeMEQLQSDWEV 839
Cdd:COG3096    353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyQQALDVQQTRAIQYQQAVQA-LEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  840 QEMKLRQDTVRLQRQVAQQEREAQRALEsqaLAHREALAqlqreketlsltlaeekEVARCQLEQEKELVTKSAAEREAL 919
Cdd:COG3096    432 PDLTPENAEDYLAAFRAKEQQATEEVLE---LEQKLSVA-----------------DAARRQFEKAYELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  920 KGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAqatisattEELKALQAQFE 999
Cdd:COG3096    492 QAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAA--------EELEELLAELE 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1000 DAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTV---AQEGLAALRQELQGVEESREGLHREAQEARRALSDEA 1076
Cdd:COG3096    564 AQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAwlaAQDALERLREQSGEALADSQEVTAAMQQLLEREREAT 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1077 REKDVLLLFNSELRATICRAEQ----EKASFKRSKEEKEQKLL-------ILEEA-----------QAALQQEASALRAH 1134
Cdd:COG3096    644 VERDELAARKQALESQIERLSQpggaEDPRLLALAERLGGVLLseiyddvTLEDApyfsalygparHAIVVPDLSAVKEQ 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1135 LWELE-------------QAGGDARQELRELHRQVRTLKAENQRRSGEAHEL----QAQCSQEVLELRRQAAKAEAKHEG 1197
Cdd:COG3096    724 LAGLEdcpedlyliegdpDSFDDSVFDAEELEDAVVVKLSDRQWRYSRFPEVplfgRAAREKRLEELRAERDELAEQYAK 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1198 ARKEVLGLQRKL--------------------AEVEAAGEAHGQrLQEHLRESRGAEQTLRAELHSVTRKLQEASGVADA 1257
Cdd:COG3096    804 ASFDVQKLQRLHqafsqfvgghlavafapdpeAELAALRQRRSE-LERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQ 882

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1258 LQARLDQ-ACHRIHSLEQELAQAEGARQDAeAQLGRLCSTLRRGLGLQRQSPwASPEQPGSPTKGSDSSQALPGQQG--- 1333
Cdd:COG3096    883 ANLLADEtLADRLEELREELDAAQEAQAFI-QQHGKALAQLEPLVAVLQSDP-EQFEQLQADYLQAKEQQRRLKQQIfal 960

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1334 TSPPARPHSPLRWPSPTPGGRSSELMDVatvqdiLRdfvQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQL 1413
Cdd:COG3096    961 SEVVQRRPHFSYEDAVGLLGENSDLNEK------LR---ARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAK 1031

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1414 QKALAEAEEGQRRVEgalssaraaralqkealrrLELEHLASVRAAGqEKRRLQEQLETLRQALEEsrrhsqgLAKQGKL 1493
Cdd:COG3096   1032 QQTLQELEQELEELG-------------------VQADAEAEERARI-RRDELHEELSQNRSRRSQ-------LEKQLTR 1084

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 1370478878 1494 LEEQLTNLEHRCQKAEVSLEPLRQMEQETLKREEDVARLGAE 1535
Cdd:COG3096   1085 CEAEMDSLQKRLRKAERDYKQEREQVVQAKAGWCAVLRLARD 1126
PRK11637 PRK11637
AmiB activator; Provisional
 646-885 5.13e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 44.30  E-value: 5.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQlegQAALLGREKAQLQEQvGQVT 725
Cdd:PRK11637    65 QQQQQRASLLAQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQQAA---QERLLAAQLDAAFRQ-GEHT 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  726 CQKQALEEQLAQSLQDQEAQMGTLQQALQGK-DALSEERAQLLAKQEALErqgrlaaeeaadlrvERDSLESSLLEAQQl 804
Cdd:PRK11637   141 GLQLILSGEESQRGERILAYFGYLNQARQETiAELKQTREELAAQKAELE---------------EKQSQQKTLLYEQQ- 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  805 atkLQEQLEEEARSaglARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQAlahREALAQLQREK 884
Cdd:PRK11637   205 ---AQQQKLEQARN---ERKKTLTGLESSLQKDQQQLSELRANESRLRDSIARAEREAKARAEREA---REAARVRDKQK 275


                   .
gi 1370478878  885 E 885
Cdd:PRK11637   276 Q 276
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 751-1159 5.86e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 5.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  751 QALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEM 830
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  831 EQLQSdwevQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEvarcQLEQEKELVT 910
Cdd:pfam02463  253 IESSK----QEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE----KLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  911 KSAAEREALKGEIQSLKQERDESLLQlehkmQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEE 990
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIK-----REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  991 LKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARR 1070
Cdd:pfam02463  400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1071 ALSDEAREKDVLLLFNSELRATICRAEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELR 1150
Cdd:pfam02463  480 VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559


                   ....*....
gi 1370478878 1151 ELHRQVRTL 1159
Cdd:pfam02463  560 VEERQKLVR 568
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1453-1639 6.13e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 6.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1453 LASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEvslEPLRQMEQETLKREEDVARL 1532
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAALEAELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1533 GAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEM------EQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQALES 1606
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1370478878 1607 QEwTHQQQVKVLEEQVASLKEQLDQEVQWRQQA 1639
Cdd:COG4942    169 LE-AERAELEALLAELEEERAALEALKAERQKL 200
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 577-828 7.28e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 7.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  577 AQLQRDVVESEREGLRSALA--RAECSNADLEllvrRLKSEGVEQRDSLA----AMAALMEGLAQDKSALNHLALQLEQE 650
Cdd:NF012221  1567 AEADRQRLEQEKQQQLAAISgsQSQLESTDQN----ALETNGQAQRDAILeesrAVTKELTTLAQGLDALDSQATYAGES 1642

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  651 RDQLREQ---------RKTLEQERARAGEQLAQAEQQL---------ALERAERrGLQQA---CGRLEQRQEQLEGQA-- 707
Cdd:NF012221  1643 GDQWRNPfagglldrvQEQLDDAKKISGKQLADAKQRHvdnqqkvkdAVAKSEA-GVAQGeqnQANAEQDIDDAKADAek 1721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  708 ----ALLGREKAQLQEQVGQVTCQKqaleeqlAQSLQDQEAQMGTLQQALQGKDALSeeraqllAKQEALER------QG 777
Cdd:NF012221  1722 rkddALAKQNEAQQAESDANAAAND-------AQSRGEQDASAAENKANQAQADAKG-------AKQDESDKpnrqgaAG 1787

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370478878  778 RLAAEEAADLRVERDSLESSLLEAQ-----QLATKLQEQLEEEARSAGLARQALQV 828
Cdd:NF012221  1788 SGLSGKAYSVEGVAEPGSHINPDSPaaadgRFSEGLTEQEQEALEGATNAVNRLQI 1843
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 541-1217 1.19e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  541 RSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKsEGVEQR 620
Cdd:TIGR00606  183 RYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLK-EIEHNL 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  621 DSLAAMAALMEGLAQDKSALNHLALQLEQERDQL----REQRKTLEQERARA----GEQLAQAEQQLALERAERRGLQQA 692
Cdd:TIGR00606  262 SKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfqgtDEQLNDLYHNHQRTvrekERELVDCQRELEKLNKERRLLNQE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  693 CGRLEQRQEQLEGQAallgrEKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMgTLQQALQGKDALSEERAQLLAKQEA 772
Cdd:TIGR00606  342 KTELLVEQGRLQLQA-----DRHQEHIRARDSLIQSLATRLELDGFERGPFSER-QIKNFHTLVIERQEDEAKTAAQLCA 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  773 -LERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLE----EEARSAGLARQALQVEMEQLQSDWEVQEMKLRQD 847
Cdd:TIGR00606  416 dLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKfvikELQQLEGSSDRILELDQELRKAERELSKAEKNSL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  848 TVRLQRQVAQQEREaQRALESQALAHREALAQLQREKETLSLTLAEEKEVA----------------------------- 898
Cdd:TIGR00606  496 TETLKKEVKSLQNE-KADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMdkdeqirkiksrhsdeltsllgyfpnkkq 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  899 -----------RCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSL--LSEELSRARRT 965
Cdd:TIGR00606  575 ledwlhskskeINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLerLKEEIEKSSKQ 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  966 LERVQQEAQ------SQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTV 1039
Cdd:TIGR00606  655 RAMLAGATAvysqfiTQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1040 AQEGLAALRQELQGVEESREGLHREAQEARRALSDEarEKDVLLLFNSELRATICRAEQE-KASFKRSKEEKEQKLlile 1118
Cdd:TIGR00606  735 RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQ--ETLLGTIMPEEESAKVCLTDVTiMERFQMELKDVERKI---- 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1119 eAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQAQCSQ---EVLELRRQAAKAEAKH 1195
Cdd:TIGR00606  809 -AQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElksEKLQIGTNLQRRQQFE 887

                          730       740
                   ....*....|....*....|..
gi 1370478878 1196 EGARKEVLGLQRKLAEVEAAGE 1217
Cdd:TIGR00606  888 EQLVELSTEVQSLIREIKDAKE 909
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 550-958 1.20e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  550 QGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAAL 629
Cdd:pfam07888   37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  630 MEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQqacGRLEQRQEQLEGQAAL 709
Cdd:pfam07888  117 KDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQ---AKLQQTEEELRSLSKE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  710 LGREKAQLQEQVGQVtcqkqaleEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRV 789
Cdd:pfam07888  194 FQELRNSLAQRDTQV--------LQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAA 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  790 ERDSLESSLLEAQQLATKLQEQLEEearsaglarqaLQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRAlesq 869
Cdd:pfam07888  266 QRDRTQAELHQARLQAAQLTLQLAD-----------ASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRL---- 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  870 alahREALAQLQREKETLSLTLAEEKEVARCQL-EQEKELVTKSAAEREALKGEIQSL--KQERDESLLQLEHKMQQALS 946
Cdd:pfam07888  331 ----EERLQEERMEREKLEVELGREKDCNRVQLsESRRELQELKASLRVAQKEKEQLQaeKQELLEYIRQLEQRLETVAD 406

                          410
                   ....*....|..
gi 1370478878  947 LKETERSLLSEE 958
Cdd:pfam07888  407 AKWSEAALTSTE 418
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 410-735 1.30e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  410 ERRWRREQELCLQLKSSQALVASLQEQLSESRR---ELWAAQKLQQERAREQAREREALRGQLEAQRLEVQQCRASCKLL 486
Cdd:pfam07888   62 ERYKRDREQWERQRRELESRVAELKEELRQSREkheELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTL 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  487 GREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREE 566
Cdd:pfam07888  142 TQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQK 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  567 LAsvrealsTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQ 646
Cdd:pfam07888  222 LT-------TAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  647 LEQERDQLREQRKTLEQER-------ARAGEQLAQAEQQLALERAERRGLQQACGR---------LEQRQEQLEGQAAL- 709
Cdd:pfam07888  295 LREGRARWAQERETLQQSAeadkdriEKLSAELQRLEERLQEERMEREKLEVELGRekdcnrvqlSESRRELQELKASLr 374

                          330       340
                   ....*....|....*....|....*..
gi 1370478878  710 -LGREKAQLQEQVGQVTCQKQALEEQL 735
Cdd:pfam07888  375 vAQKEKEQLQAEKQELLEYIRQLEQRL 401
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 633-1082 1.38e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.63  E-value: 1.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  633 LAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQ-------QACGRLEQRQEQLEG 705
Cdd:pfam01576   66 LAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQlekvtteAKIKKLEEDILLLED 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  706 QAALLGREKAQLQEQVGQVTCQkQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAK-QEALERQGRLAAEEA 784
Cdd:pfam01576  146 QNSKLSKERKLLEERISEFTSN-LAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKaKRKLEGESTDLQEQI 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  785 ADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQA---LQVEMEQLQSDWEVQEM------KLRQDTVR----- 850
Cdd:pfam01576  225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKireLEAQISELQEDLESERAarnkaeKQRRDLGEeleal 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  851 -------LQRQVAQQEREAQR---------ALESQALAHREALAQLQREKETLSLTLAEEKEVA---RCQLEQEKELVTK 911
Cdd:pfam01576  305 kteledtLDTTAAQQELRSKReqevtelkkALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAkrnKANLEKAKQALES 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  912 SAAEREALKGEIQSLKQERDESLLQLEHKMQQ---ALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAqatiSATT 988
Cdd:pfam01576  385 ENAELQAELRTLQQAKQDSEHKRKKLEGQLQElqaRLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKN----IKLS 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  989 EELKALQAQFEDAITAHQRET-----------------TALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQEL 1051
Cdd:pfam01576  461 KDVSSLESQLQDTQELLQEETrqklnlstrlrqlederNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL 540

                          490       500       510
                   ....*....|....*....|....*....|.
gi 1370478878 1052 QGVEESREGLHREAQEARRALSDEAREKDVL 1082
Cdd:pfam01576  541 EALEEGKKRLQRELEALTQQLEEKAAAYDKL 571
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 482-725 1.65e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 43.13  E-value: 1.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  482 SCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLL----LQAERREELAlrrERSCRALETSQGRLQQLE 557
Cdd:pfam13166  216 KAEILIQKVIGKSSAIEELIKNPDLADWVEQGLELHKAHLDTCPFcgqpLPAERKAALE---AHFDDEFTEFQNRLQKLI 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  558 EKVSGLREELASVREALSTAQLQRDVVESEREGLRSAlarAECSNADLELLVRRL--KSEGVEQRDSLAAMAALMEGLAQ 635
Cdd:pfam13166  293 EKVESAISSLLAQLPAVSDLASLLSAFELDVEDIESE---AEVLNSQLDGLRRALeaKRKDPFKSIELDSVDAKIESIND 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  636 DKSALNhlalqlEQERDQlREQRKTLEQERARAGEQL-----AQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALL 710
Cdd:pfam13166  370 LVASIN------ELIAKH-NEITDNFEEEKNKAKKKLrlhlvEEFKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKL 442

                          250
                   ....*....|....*
gi 1370478878  711 GREKAQLQEQVGQVT 725
Cdd:pfam13166  443 REEIKELEAQLRDHK 457
COG3903 COG3903
Predicted ATPase [General function prediction only];
388-805 1.79e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 43.08  E-value: 1.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  388 SPPHICSPATLDPALQAMRAAIERRWRR-EQELCLQLKSSQALVASLQEQLSESRRELWAAQKLQQERAREQAREREALR 466
Cdd:COG3903    511 GPDQLAWLARLDAEHDNLRAALRWALAHgDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAA 590

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  467 GQLEAQRLEVQQCRASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRAL 546
Cdd:COG3903    591 AAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAA 670

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  547 ETSQGRLQQLEEkvSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAM 626
Cdd:COG3903    671 AAAAAAAAAAAA--AAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALA 748

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  627 AALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQ 706
Cdd:COG3903    749 AAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAA 828

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  707 AALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAAD 786
Cdd:COG3903    829 ALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAA 908

                          410
                   ....*....|....*....
gi 1370478878  787 LRVERDSLESSLLEAQQLA 805
Cdd:COG3903    909 AAAAAAAALAAAAAAAAAA 927
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 644-785 2.26e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.49  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  644 ALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERrglQQAcgrLEQRQEQLEGQAALLGREKAQLQEQVGQ 723
Cdd:PRK09510    89 AEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQ---KQA---EEAAAKAAAAAKAKAEAEAKRAAAAAKK 162

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370478878  724 VTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAA 785
Cdd:PRK09510   163 AAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKAAAEAK 224
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1117-1293 2.44e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 2.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1117 LEEAQAALQqEASALRAHLWELEQAGGD---ARQELRELHRQVRTLKAE-NQRRSGEAHELQAQCSQEVLELRRQAAKAE 1192
Cdd:COG4913    237 LERAHEALE-DAREQIELLEPIRELAERyaaARERLAELEYLRAALRLWfAQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1193 AKHEGARKEVLGLQRKLAEV----EAAGEAHGQRLQEHLRESRGAEQTLRAELHSVTrklQEASGVADALQARLDQACHR 1268
Cdd:COG4913    316 ARLDALREELDELEAQIRGNggdrLEQLEREIERLERELEERERRRARLEALLAALG---LPLPASAEEFAALRAEAAAL 392

                          170       180
                   ....*....|....*....|....*
gi 1370478878 1269 IHSLEQELAQAEGARQDAEAQLGRL 1293
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDL 417
PRK12705 PRK12705
hypothetical protein; Provisional
 607-796 2.59e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 42.39  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  607 LLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLAlERAER 686
Cdd:PRK12705    21 LVVLLKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLD-ARAEK 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  687 RGLQQAcgRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQA-LEEQLAQSLQDQeaqmgtLQQALQGKDALSEERAQ 765
Cdd:PRK12705   100 LDNLEN--QLEEREKALSARELELEELEKQLDNELYRVAGLTPEqARKLLLKLLDAE------LEEEKAQRVKKIEEEAD 171

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1370478878  766 LLAKQEAL----ERQGRLAAEEAADLRVERDSLES 796
Cdd:PRK12705   172 LEAERKAQnilaQAMQRIASETASDLSVSVVPIPS 206
PRK09039 PRK09039
peptidoglycan -binding protein;
654-787 2.62e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.88  E-value: 2.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  654 LREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRL-------EQRQEQLEGQAALLGREKAQLQEQVGQVTc 726
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLraslsaaEAERSRLQALLAELAGAGAAAEGRAGELA- 122

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370478878  727 qkQALEEQLAQSLQDQeAQMGTLQQalqgkdALSEERAQLLAKQEAL---ERQGRLAAEEAADL 787
Cdd:PRK09039   123 --QELDSEKQVSARAL-AQVELLNQ------QIAALRRQLAALEAALdasEKRDRESQAKIADL 177
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1440-1634 2.91e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1440 LQKEALRRLELEHLASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEhrcQKAEVSLEPLRQME 1519
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE---LELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1520 QETLKREEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQRLQDLTA-----QHQRDLATEAERLH 1594
Cdd:COG1196    295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEaeaelAEAEEALLEAEAEL 374

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1370478878 1595 GARPQATQALESQEWTHQQQVKVLEEQVASLKEQLDQEVQ 1634
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 563-788 3.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  563 LREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEgveqrdslaaMAALMEGLAQDKSALNH 642
Cdd:COG4942     25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----------LAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  643 LALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQAcgrLEQRQEQLEG---QAALLGREKAQLQE 719
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL---APARREQAEElraDLAELAALRAELEA 171

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  720 QVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLR 788
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1096-1329 3.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1096 AEQEKASFKRSKEEKEQKLLILEEAQAALQQEASALRAHLWELEQAGGDARQELRELHRQVRTLKAENQRRSGEAHELQA 1175
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1176 QCSQEVLELRRQAAKAEAKHEGARKEVLGLQRKLAEVEAAGEAHG------QRLQEHLRESRGAEQTLRAELHSVTRKLQ 1249
Cdd:COG4942     98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKylaparREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1250 EASGVADALQARLDQACHRIHSLEQELAQAEGARQDAEAQLGRLCSTLRRGL-GLQRQSPWASPEQPGSPTKGSDSSQAL 1328
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIaRLEAEAAAAAERTPAAGFAALKGKLPW 257


                   .
gi 1370478878 1329 P 1329
Cdd:COG4942    258 P 258
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
641-814 3.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  641 NHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQ--RQEQLEGQAALLGREKAQLQ 718
Cdd:COG3206    204 KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELS 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  719 EQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQgrlAAEEAADLRVERDSLESSL 798
Cdd:COG3206    284 ARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEA---RLAELPELEAELRRLEREV 360

                          170
                   ....*....|....*.
gi 1370478878  799 LEAQQLATKLQEQLEE 814
Cdd:COG3206    361 EVARELYESLLQRLEE 376
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 577-743 3.25e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 41.64  E-value: 3.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  577 AQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLrE 656
Cdd:pfam00529   49 FQLDPTDYQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDL-A 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  657 QRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAAllgrekAQLQEQVGQVTCQKQALEEQLA 736
Cdd:pfam00529  128 RRRVLAPIGGISRESLVTAGALVAQAQANLLATVAQLDQIYVQITQSAAENQ------AEVRSELSGAQLQIAEAEAELK 201


                   ....*..
gi 1370478878  737 QSLQDQE 743
Cdd:pfam00529  202 LAKLDLE 208
PRK11281 PRK11281
mechanosensitive channel MscK;
462-819 3.53e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 3.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  462 REALRGQLEAQrlevqqcrASCKLLGREKAALEMVVEELKGKADAADAEKQGLEAEAAELQRSLLLQAERREEL-ALRRE 540
Cdd:PRK11281    38 EADVQAQLDAL--------NKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELeALKDD 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  541 RSCRALETSQGR-LQQLEEKVSGLREELASVREALSTA--QL--QRDVVESEREGLRSALARAECSNADLELLVRRLKSE 615
Cdd:PRK11281   110 NDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYnsQLvsLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKAL 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  616 GVEQRDSLAAMAALMEglaqdksALNHLALQLEQERDQLREqrkTLEQERARAGEQLAQAEQQLALeraerrgLQQACG- 694
Cdd:PRK11281   190 RPSQRVLLQAEQALLN-------AQNDLQRKSLEGNTQLQD---LLQKQRDYLTARIQRLEHQLQL-------LQEAINs 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  695 -RLEQRQEQLegqaallgrEKAQLQEQVGQVTC-----QKQALEEQLAQSLQDQEAQMGTL-QQALQGKDALseERAQ-- 765
Cdd:PRK11281   253 kRLTLSEKTV---------QEAQSQDEAARIQAnplvaQELEINLQLSQRLLKATEKLNTLtQQNLRVKNWL--DRLTqs 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  766 ---------------LLAK-----QEALERQGRLA--AEEAADLRVE-------RDSLESSLLEAQQLATKLQEQLEEEA 816
Cdd:PRK11281   322 ernikeqisvlkgslLLSRilyqqQQALPSADLIEglADRIADLRLEqfeinqqRDALFQPDAYIDKLEAGHKSEVTDEV 401


                   ...
gi 1370478878  817 RSA 819
Cdd:PRK11281   402 RDA 404
PRK12704 PRK12704
phosphodiesterase; Provisional
 623-817 3.65e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 3.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  623 LAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLEQERAR-----AGEQLAQAEQQLALERAERRG-LQQACGRL 696
Cdd:PRK12704    12 VALVVGAVIGYFVRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKealleAKEEIHKLRNEFEKELRERRNeLQKLEKRL 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  697 EQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQlaqslqdqeaqmgtlqqalqgkdalSEERAQLLAKQ-EALER 775
Cdd:PRK12704    92 LQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKK-------------------------EEELEELIEEQlQELER 146

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1370478878  776 QGRLAAEEAADLRVERdsLESsllEAQQLATKLQEQLEEEAR 817
Cdd:PRK12704   147 ISGLTAEEAKEILLEK--VEE---EARHEAAVLIKEIEEEAK 183
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
546-838 3.82e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  546 LETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAECSNADLELLVRRLKSEGVEQRDSLAA 625
Cdd:COG4372     40 LDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEE 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  626 MAALMEglaqdksalnhlalQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEG 705
Cdd:COG4372    120 LQKERQ--------------DLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAL 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  706 QAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAA 785
Cdd:COG4372    186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELEL 265

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1370478878  786 DLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWE 838
Cdd:COG4372    266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALL 318
PRK09039 PRK09039
peptidoglycan -binding protein;
708-864 3.91e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.49  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  708 ALLGREKA--QLQEQVGQVTcQKQALEEQLAQSLQDQEAQmgtLQQALQGKDAlseERAQLLAKQEALERQGRLAAEEAA 785
Cdd:PRK09039    47 EISGKDSAldRLNSQIAELA-DLLSLERQGNQDLQDSVAN---LRASLSAAEA---ERSRLQALLAELAGAGAAAEGRAG 119

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370478878  786 DLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSdwevQEMKLRQDTVRLQRQVAQQEREAQR 864
Cdd:PRK09039   120 ELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRE----SQAKIADLGRRLNVALAQRVQELNR 194
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 603-689 4.07e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 4.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  603 ADLELLVRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLALQLEQERDQLREQRKTLE--------QERARAGEQLAQ 674
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQekaaetsqERKQKRKEITDQ 224

                           90
                   ....*....|....*
gi 1370478878  675 AEQQLALERAERRGL 689
Cdd:PRK11448   225 AAKRLELSEEETRIL 239
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 430-921 4.38e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.03  E-value: 4.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  430 VASLQEQLSESRRELWAAQKLQQERAREQAR---EREALRGQLEAQRLEVQQCRASCKLLGREKAALEMVVEELKGKADA 506
Cdd:pfam15921  344 IEELEKQLVLANSELTEARTERDQFSQESGNlddQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDD 423

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  507 ADAEKQGLEAEAAELQRSLLLQAERREELALRRERSCRALETSQGRLQQLEEKVSGLREELASVREALSTAQ-----LQR 581
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSErtvsdLTA 503

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  582 DVVESER--EGLRSALARAEcSNADLELL-VRRLKSEGVEQRDSLAAMAALMEGLAQDKSALNHLalqleqeRDQLREQR 658
Cdd:pfam15921  504 SLQEKERaiEATNAEITKLR-SRVDLKLQeLQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEIL-------RQQIENMT 575

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  659 KTLEQERARAGEQL---AQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQL----QEQVGQVTCQKQAl 731
Cdd:pfam15921  576 QLVGQHGRTAGAMQvekAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvnagSERLRAVKDIKQE- 654

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  732 EEQLAQSLQDQEAQMGTLQQALQG-KDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQE 810
Cdd:pfam15921  655 RDQLLNEVKTSRNELNSLSEDYEVlKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK 734

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  811 QLEEEARSAGLARQALQVeMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQR------ALESQALAHREALAQLQREK 884
Cdd:pfam15921  735 QITAKRGQIDALQSKIQF-LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmageleVLRSQERRLKEKVANMEVAL 813

                          490       500       510
                   ....*....|....*....|....*....|....*..
gi 1370478878  885 ETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKG 921
Cdd:pfam15921  814 DKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
COG3899 COG3899
Predicted ATPase [General function prediction only];
664-1101 4.40e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.77  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  664 ERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQE 743
Cdd:COG3899    807 EEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAAL 886

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  744 AQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLAR 823
Cdd:COG3899    887 AAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAA 966

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  824 QALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLE 903
Cdd:COG3899    967 AAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALL 1046

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  904 QEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQAT 983
Cdd:COG3899   1047 AALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALA 1126

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  984 ISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHR 1063
Cdd:COG3899   1127 AAARAAAALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARL 1206

                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 1370478878 1064 EAQEARRALSDEAREKDVLLLFNSELRATICRAEQEKA 1101
Cdd:COG3899   1207 AALLALALLALEAAALLLLLLLAALALAAALLALRLLA 1244
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 547-836 4.69e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 41.55  E-value: 4.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  547 ETSQGRLQQLEEKVSGLREELASVREALSTAQLQRDVVESERE--GLRSALARAECSNADLELLVRRLKSEGveqRDSLA 624
Cdd:pfam05667  185 EFYSEYLPPVTAQPSSRASVVPSLLERNAAELAAAQEWEEEWNsqGLASRLTPEEYRKRKRTKLLKRIAEQL---RSAAL 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  625 AMAALMEGLAQDKSALNHL--ALQLEQERDQL--------REQRKTLEQERARAGEQLA---QAEQQLALER-AERRGLQ 690
Cdd:pfam05667  262 AGTEATSGASRSAQDLAELlsSFSGSSTTDTGltkgsrftHTEKLQFTNEAPAATSSPPtkvETEEELQQQReEELEELQ 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  691 QACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQS------LQDQEAQMGTLQQALqgkDALSEERA 764
Cdd:pfam05667  342 EQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYKVKkktldlLPDAEENIAKLQALV---DASAQRLV 418

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  765 QLLAKQEalERQGRLAAEeaadLRVERDSLESSLLEAQQLATKLQE------QLEEEARSAGLARQALQVEMEQLQSD 836
Cdd:pfam05667  419 ELAGQWE--KHRVPLIEE----YRALKEAKSNKEDESQRKLEEIKElrekikEVAEEAKQKEELYKQLVAEYERLPKD 490
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 660-827 4.73e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 41.25  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  660 TLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLqeqvgqvtcqkQALEEQLAQSL 739
Cdd:pfam00529   55 DYQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAV-----------KAAQAQLAQAQ 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  740 QDQEAQMGTLQQALQGKDALSEERAQLL-AKQEALERQGRLAAEEAADLRVERDSLEssllEAQQLATKLQEQLEEEARS 818
Cdd:pfam00529  124 IDLARRRVLAPIGGISRESLVTAGALVAqAQANLLATVAQLDQIYVQITQSAAENQA----EVRSELSGAQLQIAEAEAE 199


                   ....*....
gi 1370478878  819 AGLARQALQ 827
Cdd:pfam00529  200 LKLAKLDLE 208
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 646-798 4.89e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAA----LLG-----REKAQ 716
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKkyeeQLGnvrnnKEYEA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  717 LQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQAlqgKDALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLES 796
Cdd:COG1579     94 LQKEIESLKRRISDLEDEILELMERIEELEEELAEL---EAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170


                   ..
gi 1370478878  797 SL 798
Cdd:COG1579    171 KI 172
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 746-1172 4.89e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.48  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  746 MGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVErDSLESSLLEAQQLATKLQEQLEEEARSAGLARQA 825
Cdd:COG5185    165 FGKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKE-SETGNLGSESTLLEKAKEIINIEEALKGFQDPES 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  826 LQVEMEQLQSDWE---VQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQL 902
Cdd:COG5185    244 ELEDLAQTSDKLEklvEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  903 EQEkelvtksaaerealkgeIQSLKQERDESLLQLEHKMQQalslketERSLLSEELSRARRTLERVQQEAQsqqeqaqa 982
Cdd:COG5185    324 EQE-----------------LEESKRETETGIQNLTAEIEQ-------GQESLTENLEAIKEEIENIVGEVE-------- 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  983 tISATTEELKALQAQ----FEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESR 1058
Cdd:COG5185    372 -LSKSSEELDSFKDTiestKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISEL 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1059 EGLHREAQEARRALSDEAREKdvlllFNSELRATICRAEQEKASFKRSKEEKEQKlliLEEAQAALQQEASALRAHLWEL 1138
Cdd:COG5185    451 NKVMREADEESQSRLEEAYDE-----INRSVRSKKEDLNEELTQIESRVSTLKAT---LEKLRAKLERQLEGVRSKLDQV 522

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1370478878 1139 EQAGGDARQELRELHrqvrTLKAENQRRSGEAHE 1172
Cdd:COG5185    523 AESLKDFMRARGYAH----ILALENLIPASELIQ 552
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 646-1037 5.24e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.70  E-value: 5.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVT 725
Cdd:pfam01576   30 ELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLE 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  726 CQKQAlEEQLAQSLQDQ----EAQMGTLQQALQgkdALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEA 801
Cdd:pfam01576  110 EQLDE-EEAARQKLQLEkvttEAKIKKLEEDIL---LLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKH 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  802 QQLATKLQEQLEEEARSAgLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALE--SQALAHREALAQ 879
Cdd:pfam01576  186 EAMISDLEERLKKEEKGR-QELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALArlEEETAQKNNALK 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  880 LQREKETLSLTLAEEkevarcqLEQEKELVTKSAAEREALKGEIQSLKQERDESlLQLEHKMQQALSLKETERSLLSEEL 959
Cdd:pfam01576  265 KIRELEAQISELQED-------LESERAARNKAEKQRRDLGEELEALKTELEDT-LDTTAAQQELRSKREQEVTELKKAL 336

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  960 SRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALRESLQDLAAERGDVEREAERLRAQL 1037
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQL 414
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 149-905 5.98e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 5.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  149 DLEEALGRLEAAEERSTGLCQVNALLREQLEHMKKANDALGRELAgmtgSVQRLQGELELRRWAQRQTRSgGLGQPRDLL 228
Cdd:COG3096    355 DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLA----DYQQALDVQQTRAIQYQQAVQ-ALEKARALC 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  229 llwrQAVVLGTDLAELRVATERGLADLQADT----------ARTARRLHTACLNLDSNL-----RLSASSTASTLGQQLR 293
Cdd:COG3096    430 ----GLPDLTPENAEDYLAAFRAKEQQATEEvleleqklsvADAARRQFEKAYELVCKIageveRSQAWQTARELLRRYR 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  294 DKAGEMLQLQGrWDAEKVALQARLSEQTLLVEKLTEQNEQKAKTIAAlRTDLQNLVAQEDARCLELAgSSITELGEPRRP 373
Cdd:COG3096    506 SQQALAQRLQQ-LRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDA-AEELEELLAELEAQLEELE-EQAAEAVEQRSE 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  374 LRSpqratspHQGASPPHICSPATLDPALQAMRAAIErrwRREQELCLQLKSSQALVASLQEQLsesrrelwaaqklqqe 453
Cdd:COG3096    583 LRQ-------QLEQLRARIKELAARAPAWLAAQDALE---RLREQSGEALADSQEVTAAMQQLL---------------- 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  454 rarEQAREREALRGQLEAQrlevqqcrasckllgreKAALEMVVEELKGKADAADAEKQGLeaeAAELQRSLLlqAERRE 533
Cdd:COG3096    637 ---EREREATVERDELAAR-----------------KQALESQIERLSQPGGAEDPRLLAL---AERLGGVLL--SEIYD 691

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  534 ELAL-------------RRERSCRALETSQGRLQQLEEKVSGL----REELASVREALSTAQLQ-RDVVESEREGLRSA- 594
Cdd:COG3096    692 DVTLedapyfsalygpaRHAIVVPDLSAVKEQLAGLEDCPEDLylieGDPDSFDDSVFDAEELEdAVVVKLSDRQWRYSr 771

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  595 ------LARAECSNaDLELLvRRLKSEGVEQRDSLAAMAALMEGLAQDKSAL--NHLALQL----EQERDQLREQRKTLE 662
Cdd:COG3096    772 fpevplFGRAAREK-RLEEL-RAERDELAEQYAKASFDVQKLQRLHQAFSQFvgGHLAVAFapdpEAELAALRQRRSELE 849

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  663 QERARAGEQLAQAEQQLALERAERRGLQQACGR--------LEQRQEQLEGQaallgREKAQLQEQVGQVTCQKQALEEQ 734
Cdd:COG3096    850 RELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQanlladetLADRLEELREE-----LDAAQEAQAFIQQHGKALAQLEP 924

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  735 LAQSLQDQEAQMGTLQQA-LQGKDALSEERAQLLAKQEALERQGRLAAEEAADLrverdslessLLEAQQLATKLQEQL- 812
Cdd:COG3096    925 LVAVLQSDPEQFEQLQADyLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGL----------LGENSDLNEKLRARLe 994

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  813 --EEEARSAGLARQALQVEMEQLQSDWevQEMKLRQDTVRLQRQVAQQEREaqrALESQALAHREALAQLQRE--KETLS 888
Cdd:COG3096    995 qaEEARREAREQLRQAQAQYSQYNQVL--ASLKSSRDAKQQTLQELEQELE---ELGVQADAEAEERARIRRDelHEELS 1069

                          810       820
                   ....*....|....*....|.
gi 1370478878  889 LTLAE----EKEVARCQLEQE 905
Cdd:COG3096   1070 QNRSRrsqlEKQLTRCEAEMD 1090
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1398-1626 6.45e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 6.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1398 EAECRCARAQSRVGQLQKALAEAEEGQRRVE--GALSSARAARALQKEALRRLE-LEHLASVRAAGQEKRRLQEQLETLR 1474
Cdd:COG4913    222 DTFEAADALVEHFDDLERAHEALEDAREQIEllEPIRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELR 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1475 QALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVsleplrqmeqetlkreEDVARLGAEKEQLDQSLnslhQEVDGAL 1554
Cdd:COG4913    302 AELARLEAELERLEARLDALREELDELEAQIRGNGG----------------DRLEQLEREIERLEREL----EERERRR 361

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370478878 1555 RQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARPQATQAlESQEWTHQQQVKVLEEQVASLK 1626
Cdd:COG4913    362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA-EAALRDLRRELRELEAEIASLE 432
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
696-1003 7.06e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 7.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  696 LEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALER 775
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  776 QGRLAAEEAADLRVERDSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQsdwEVQEMKLRQDTVRLQRQV 855
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELA---ALEQELQALSEAEAEQAL 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  856 AQQEREAQRALESQALAHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLL 935
Cdd:COG4372    186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELEL 265

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878  936 QLEHKMQQALSLKETERSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAIT 1003
Cdd:COG4372    266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALA 333
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1368-1598 7.15e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 7.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1368 LRDFVQKLREAQRERDDSRIQMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEGQRRVEGALSSARAARALQKEALRR 1447
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1448 LELEHLASVRAAGQEKRRLQEQLETLRQALEESRRHSQGLAKQGKLLEEQLTNLEHRCQKAEVSLEPLRQMEQETLKREE 1527
Cdd:COG4942    109 LLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA 188

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370478878 1528 DVARLGAEKEQLdqsLNSLHQEVDGALRQNQQLQAQMTEMEQAHTQRLQDLTAQHQRDLATEAERLHGARP 1598
Cdd:COG4942    189 ALEALKAERQKL---LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLP 256
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1347-1570 7.50e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.19  E-value: 7.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1347 PSPTPGGRSSELMDVATVQdILRDFVQKLREAQRERDDSRI---QMATLSSRLSEAECRCARAQSRVGQLQKALAEAEEG 1423
Cdd:PRK10929    95 PRSVPPNMSTDALEQEILQ-VSSQLLEKSRQAQQEQDRAREisdSLSQLPQQQTEARRQLNEIERRLQTLGTPNTPLAQA 173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878 1424 QRrvegalSSARAARALQKEALRRLELEHL-ASVRaagQEKRRLQEQLEtlrqaleeSRRHSQgLAKQGKLLEEQLTNLe 1502
Cdd:PRK10929   174 QL------TALQAESAALKALVDELELAQLsANNR---QELARLRSELA--------KKRSQQ-LDAYLQALRNQLNSQ- 234

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370478878 1503 hRCQKAEVSLEPLRQMEQETLKREEDVARLGAEKEQLDQSLNSLHQEVDGALRQNQQLQAQMTEMEQA 1570
Cdd:PRK10929   235 -RQREAERALESTELLAEQSGDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQA 301
PRK09039 PRK09039
peptidoglycan -binding protein;
930-1083 7.84e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 40.33  E-value: 7.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  930 RDESLLQLEHKMQQ---ALSLKETERSLLSEELSRARrtlervqqeaqsqqeqaqatisATTEELKALQAQFEDAITAHQ 1006
Cdd:PRK09039    51 KDSALDRLNSQIAEladLLSLERQGNQDLQDSVANLR----------------------ASLSAAEAERSRLQALLAELA 108

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370478878 1007 RETTALRESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQGVEESREGLHREAQEARRALSDEAREKDVLL 1083
Cdd:PRK09039   109 GAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLGRRLNVAL 185
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 690-781 7.88e-03

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 39.88  E-value: 7.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  690 QQACGRLEQRQEQLEGQAALLGREkaQLQEQVGQVTCQKQALEEQlaQSLQDQEAQmgtLQQALQGKDALSEERAQLLAK 769
Cdd:NF038305   115 QQAGQQETQLQQQLNQLQAQTSPQ--QLNQLLKSEQKQGQALASG--QLPEEQKEQ---LQQFKSNPQALDKFLAQQLTQ 187

                           90
                   ....*....|....*.
gi 1370478878  770 ----QEALERQGRLAA 781
Cdd:NF038305   188 irtqAEEAEKQARLEA 203
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
553-1008 8.26e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 40.66  E-value: 8.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  553 LQQLEEKVSGLREELASVREALSTAQLQRDVVESEREGLRSALARAEcsnaDLELLVRRLKSEGVEQRDSLAAMAALMEG 632
Cdd:COG5278     78 LEPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELE----QVIALRRAGGLEAALALVRSGEGKALMDE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  633 LAQDKSALNHLALQLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQACGRLEQRQEQLEGQAALLGR 712
Cdd:COG5278    154 IRARLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  713 EKAQLQEQVGQVT-CQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAADLRVER 791
Cdd:COG5278    234 LLAALALALALLLaALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAA 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  792 DSLESSLLEAQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQAL 871
Cdd:COG5278    314 AAAAAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVL 393

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  872 AHREALAQLQREKETLSLTLAEEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLLQLEHKMQQALSLKETE 951
Cdd:COG5278    394 AIAAAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAA 473

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370478878  952 RSLLSEELSRARRTLERVQQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRE 1008
Cdd:COG5278    474 LAALAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
727-845 9.02e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 40.03  E-value: 9.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  727 QKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALERQGRLAAEEAA------DLRVERDSLESSLLE 800
Cdd:COG1566     87 QAEAQLAAAEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVsqqeldEARAALDAAQAQLEA 166

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1370478878  801 AQQLATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLR 845
Cdd:COG1566    167 AQAQLAQAQAGLREEEELAAAQAQVAQAEAALAQAELNLARTTIR 211
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 646-879 9.53e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.20  E-value: 9.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  646 QLEQERDQLREQRKTLEQERARAGEQLAQAEQQLALERAERRGLQQacgRLEQRQEQLEGQAALLGREKAQLQEQVGQVT 725
Cdd:COG3883     27 ELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQA---EIAEAEAEIEERREELGERARALYRSGGSVS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  726 CQKQALEEQLAQSLQDQEAQMGTLQQALQGK-DALSEERAQLLAKQEALERQGRLAAEEAADLRVERDSLESSLLEAQQL 804
Cdd:COG3883    104 YLDVLLGSESFSDFLDRLSALSKIADADADLlEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370478878  805 ATKLQEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLQRQVAQQEREAQRALESQALAHREALAQ 879
Cdd:COG3883    184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 696-1052 9.75e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 40.26  E-value: 9.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  696 LEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQALQGKDALSEERAQLLAKQEALER 775
Cdd:pfam07888   50 QEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEA 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  776 QGRLAAEEAADLRVERDSLESSLleaqqlatklqEQLEEEARSAGLARQALQVEMEQLQSDWEVQEMKLRQDTVRLqrqv 855
Cdd:pfam07888  130 RIRELEEDIKTLTQRVLERETEL-----------ERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEF---- 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  856 aQQEREAQRALESQALAHREALAQLQREKETLSLTLAeEKEVARCQLEQEKELVTKSAAEREALKGEIQSLKQERDESLL 935
Cdd:pfam07888  195 -QELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEA-ENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQA 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  936 QLEHKMQQA--LSLKETERSLLSEElSRARRTLERvqQEAQSQQEQAQATISATTEELKALQAQFEDAITAHQRETTALR 1013
Cdd:pfam07888  273 ELHQARLQAaqLTLQLADASLALRE-GRARWAQER--ETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELG 349

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 1370478878 1014 ESLQDLAAERGDVEREAERLRAQLTVAQEGLAALRQELQ 1052
Cdd:pfam07888  350 REKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQ 388
46 PHA02562
endonuclease subunit; Provisional
 687-896 9.86e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 40.38  E-value: 9.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  687 RGLQQACGRLEQRQEQLEGQAALLGREKAQLQEQVGQVTCQKQALEEQLAQSLQDQEAQMGTLQQAL-----QGKD---- 757
Cdd:PHA02562   177 RELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELlnlvmDIEDpsaa 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370478878  758 --ALSEERAQLLAKQEALERQGRLAAE-----------EAADLRVErdSLESSLLEAQQLATKLQEQLEEEARSAGLARQ 824
Cdd:PHA02562   257 lnKLNTAAAKIKSKIEQFQKVIKMYEKggvcptctqqiSEGPDRIT--KIKDKLKELQHSLEKLDTAIDELEEIMDEFNE 334

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370478878  825 aLQVEMEQLQSDWEvqemKLRQDTVRLQRQVAQQEREAQRaLESQALAHREALAQLQREKETLSLTLAEEKE 896
Cdd:PHA02562   335 -QSKKLLELKNKIS----TNKQSLITLVDKAKKVKAAIEE-LQAEFVDNAEELAKLQDELDKIVKTKSELVK 400
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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