|
Name |
Accession |
Description |
Interval |
E-value |
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1-1099 |
0e+00 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 1610.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 1 MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASRDLSSEEMMMMSSSPS 80
Cdd:TIGR00927 1 MGKLIRMGTQERRLLRPKRLHWSRLLFLLGMLIIGSTYQHLRRPQGLPSLWAAVSSQQPIKLASRDLSNDEMMMVSSDPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 81 KPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTS-SRTLTYYTSTSS 159
Cdd:TIGR00927 81 KSSSEMEGEMLAPQATVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTPATpSRALNHYISTSG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 160 RQIVKKYTPTPRGEMKSYSPTQVREKV-KYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLK 238
Cdd:TIGR00927 161 RQRVKSYTPKPRGEVKSSSPTQTREKVrKYTPSPLGRMVNSYAPSTFMTMPRSHGITPRTTVKDSEITATYKMLETNPSK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 239 RIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPAT 318
Cdd:TIGR00927 241 RTAGKTTPTPLKGMTDNTPTFLTREVETDLLTSPRSVVEKNTLTTPRRVESNSSTNHWGLVGKNNLTTPQGTVLEHTPAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 319 SEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVK 398
Cdd:TIGR00927 321 SEGQVTISIMTGSSPAETKASTAAWKIRNPLSRTSAPAVRIASATFRGLEKNPSTAPSTPATPRVRAVLTTQVHHCVVVK 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 399 PTPAMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFV 478
Cdd:TIGR00927 401 PAPAVPTTPSPSLTTALFPEAPSPSPSALPPGQPDLHPKAEYPPDLFSVEERRQGWVVLHIFGMMYVFVALAIVCDEYFV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 479 PALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPL 558
Cdd:TIGR00927 481 PALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 559 FRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPVAKVMALEDLSKpgdgaiav 638
Cdd:TIGR00927 561 FRDVSFYILDLMMLILFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPVAKVMALGDLSK-------- 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 639 delqdnkklklpslltrgssstslhnstirstiyqlmlhsldplrevrlakekeeeslnqGARAQPQAKAESKPEEEEPA 718
Cdd:TIGR00927 633 ------------------------------------------------------------GDVAEAEHTGERTGEEGERP 652
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 719 klpavTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPG---------------EEGETAGEGETEEKSGGETQPEG-- 781
Cdd:TIGR00927 653 -----TEAEGENGEESGGEAEQEGETETKGENESEGEIPAerkgeqegegeieakEADHKGETEAEEVEHEGETEAEGte 727
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 782 -EGETETQGKGEE--------CEDENEAEGKGDN--------------EGEDEGEIHA-EDGEMKGNEG----------- 826
Cdd:TIGR00927 728 dEGEIETGEEGEEvedegegeAEGKHEVETEGDRketehegeteaegkEDEDEGEIQAgEDGEMKGDEGaegkveheget 807
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 827 -----------------------ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883
Cdd:TIGR00927 808 eagekdehegqsetqaddtevkdETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEE 887
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 884 EEeeeeekgNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVG 963
Cdd:TIGR00927 888 EE-------NEEPLSLEWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQEARKFFVITFLGSIMWIAMFSYLMVWWAHQVG 960
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 964 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFC 1043
Cdd:TIGR00927 961 ETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFC 1040
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*.
gi 1370467485 1044 AIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1099
Cdd:TIGR00927 1041 AIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1096
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
457-611 |
6.09e-44 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 162.11 E-value: 6.09e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 457 LHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNI 536
Cdd:TIGR00367 1 LLLIGYLILGLILLIYGADLFVKSSVRIARHLGISPLIIGVTVVAIGTSLPELFTSLIASLMGQPDIGVGNVIGSNIFNI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370467485 537 LFVIGTCSLFSrEILNLTWWpLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYvftMKWNKHIEVWVK 611
Cdd:TIGR00367 81 LLILGLSAIFS-PIIVDKDW-LRRDILFYLLVSILLLFFGLDGQISRIDGVVLLILYIVY---LLFLVKNERWVK 150
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
932-1081 |
7.33e-39 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 147.09 E-value: 7.33e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 932 ESRKFFVFTFL---GSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVG 1008
Cdd:TIGR00367 163 NRRPQIFFSLVlliIGLIGLVVGSRLLVDGAVKIAEILGISEKIIGLTLLAIGTSLPELVVSLAAARKGLGDIAVGNVIG 242
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370467485 1009 SNIFDITVGLPVPWLLFSLIngLQPVPVSSNGLFCAIVLLFLMLLFVIsSIASCKWrmnkiLGFTMFLLYFVF 1081
Cdd:TIGR00367 243 SNIFNILVGLGVPSLFMPIP--VEPLAYNLDAPVMVIVTLLLMLFFKT-SMKLGRW-----EGILLLALYIAY 307
|
|
| Na_Ca_ex |
pfam01699 |
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral ... |
458-602 |
7.35e-31 |
|
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral membrane proteins. This family covers the integral membrane regions of the proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells. Ca2+ is moved into or out of the cytosol depending on Na+ concentration. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3.
Pssm-ID: 426387 [Multi-domain] Cd Length: 149 Bit Score: 118.86 E-value: 7.35e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 458 HVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNIL 537
Cdd:pfam01699 1 LSLLLFILGLLLISVAADLLVDSAEVLARVLGISGTVLGLTILALGTSLPELVSSIIAALRGEPDLALGNVIGSNIFNIL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370467485 538 FVIGTCSLFSREILNLTW----WPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKW 602
Cdd:pfam01699 81 LVLGLSALIGPVKVDSLLlkldLGVLLLVALLLLLLLLLLLLPLFGRLSRFEGLVLLLLYIVYLVFQIV 149
|
|
| Na_Ca_ex |
pfam01699 |
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral ... |
936-1087 |
8.85e-30 |
|
Sodium/calcium exchanger protein; This is a family of sodium/calcium exchanger integral membrane proteins. This family covers the integral membrane regions of the proteins. Sodium/calcium exchangers regulate intracellular Ca2+ concentrations in many cells; cardiac myocytes, epithelial cells, neurons retinal rod photoreceptors and smooth muscle cells. Ca2+ is moved into or out of the cytosol depending on Na+ concentration. In humans and rats there are 3 isoforms; NCX1 NCX2 and NCX3.
Pssm-ID: 426387 [Multi-domain] Cd Length: 149 Bit Score: 115.78 E-value: 8.85e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 936 FFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDIT 1015
Cdd:pfam01699 1 LSLLLFILGLLLISVAADLLVDSAEVLARVLGISGTVLGLTILALGTSLPELVSSIIAALRGEPDLALGNVIGSNIFNIL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370467485 1016 VGLPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIascKWRMNKILGFTMFLLYFVFLIISVM 1087
Cdd:pfam01699 81 LVLGLSALIGPVKVDSLLLKLDLGVLLLVALLLLLLLLLLLLPL---FGRLSRFEGLVLLLLYIVYLVFQIV 149
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
475-600 |
2.90e-24 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 104.06 E-value: 2.90e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 475 EYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSReiLNLT 554
Cdd:COG0530 2 DLLVRGADALARRLGISPLVIGLTIVAFGTSLPELAVSVTAALDGSPDIAVGNVVGSNIANILLILGLAALIRP--LAVD 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1370467485 555 WWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 600
Cdd:COG0530 80 RRVLRRDLPFLLLASLLLLALLLDGTLSRIDGVILLLLYVLYLYYL 125
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
925-1084 |
4.09e-23 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 100.98 E-value: 4.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 925 VPDVRRQESRKFFVFTFLGSIMwIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVS 1004
Cdd:COG0530 142 LEEKPKMSLWKALLLLVLGLAL-LVVGARLLVDGAVEIARALGVSELVIGLTIVAIGTSLPELATSIVAARKGEDDLAVG 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 1005 SSVGSNIFDITVGLPVPWLlfslingLQPVPVSSN------------GLFCAIvllflmllfvissIASCKWRMNKILGF 1072
Cdd:COG0530 221 NIIGSNIFNILLVLGIGAL-------ITPIPVDPAvlsfdlpvmlaaTLLLLG-------------LLRTGGRIGRWEGL 280
|
170
....*....|..
gi 1370467485 1073 TMFLLYFVFLII 1084
Cdd:COG0530 281 LLLALYLAYLAL 292
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
462-600 |
1.46e-17 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 84.41 E-value: 1.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 462 MMYVFVALA--IVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFV 539
Cdd:COG0530 154 LLLLVLGLAllVVGARLLVDGAVEIARALGVSELVIGLTIVAIGTSLPELATSIVAARKGEDDLAVGNIIGSNIFNILLV 233
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370467485 540 IGTCSLFSReiLNLTWWPLFRDVSFYILDLIMLILFFL-DSLIAWWESLLLLLAYAFYVFTM 600
Cdd:COG0530 234 LGIGALITP--IPVDPAVLSFDLPVMLAATLLLLGLLRtGGRIGRWEGLLLLALYLAYLALL 293
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
967-1024 |
1.37e-13 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 73.14 E-value: 1.37e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1370467485 967 GISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLL 1024
Cdd:PRK10734 205 AISELTIGLTVIAIGTSLPELATAIAGARKGENDIAVGNIIGSNIFNIVIVLGLPALI 262
|
|
| ECM27 |
COG0530 |
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; |
959-1041 |
8.66e-13 |
|
Ca2+/Na+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 440296 [Multi-domain] Cd Length: 293 Bit Score: 70.16 E-value: 8.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 959 AHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFslinglqPVPVSS 1038
Cdd:COG0530 8 ADALARRLGISPLVIGLTIVAFGTSLPELAVSVTAALDGSPDIAVGNVVGSNIANILLILGLAALIR-------PLAVDR 80
|
...
gi 1370467485 1039 NGL 1041
Cdd:COG0530 81 RVL 83
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
465-586 |
2.87e-12 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 68.89 E-value: 2.87e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 465 VFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCS 544
Cdd:TIGR00367 177 IGLIGLVVGSRLLVDGAVKIAEILGISEKIIGLTLLAIGTSLPELVVSLAAARKGLGDIAVGNVIGSNIFNILVGLGVPS 256
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1370467485 545 LFSR-EILNLTwwpLFRDVSFYILDLIMLILFF-LDSLIAWWES 586
Cdd:TIGR00367 257 LFMPiPVEPLA---YNLDAPVMVIVTLLLMLFFkTSMKLGRWEG 297
|
|
| TIGR00367 |
TIGR00367 |
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and ... |
962-1089 |
1.46e-10 |
|
K+-dependent Na+/Ca+ exchanger related-protein; This model models a family of bacterial and archaeal proteins that is homologous, except for lacking a central region of ~ 250 amino acids and an N-terminal region of > 100 residues, to a functionally proven potassium-dependent sodium-calcium exchanger of the rat. [Unknown function, General]
Pssm-ID: 273039 [Multi-domain] Cd Length: 307 Bit Score: 63.88 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 962 VGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLlfslingLQPVPVSSNGL 1041
Cdd:TIGR00367 28 IARHLGISPLIIGVTVVAIGTSLPELFTSLIASLMGQPDIGVGNVIGSNIFNILLILGLSAI-------FSPIIVDKDWL 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1370467485 1042 FcaIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLE 1089
Cdd:TIGR00367 101 R--RDILFYLLVSILLLFFGLDGQISRIDGVVLLILYIVYLLFLVKNE 146
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
462-543 |
1.55e-09 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 62.12 E-value: 1.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 462 MMYVFVALAIVCDEyFVPALGVITDK-----------------LQI-SEDVAGATFMAAGGSAPELFTSLIGV----FIS 519
Cdd:TIGR00845 82 MVYMFLGVSIIADR-FMASIEVITSQekeitikkpngettvttVRIwNETVSNLTLMALGSSAPEILLSVIEVcghnFEA 160
|
90 100
....*....|....*....|....
gi 1370467485 520 hSNVGIGTIVGSAVFNILFVIGTC 543
Cdd:TIGR00845 161 -GDLGPSTIVGSAAFNMFIIIAIC 183
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
483-547 |
1.78e-07 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 54.27 E-value: 1.78e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370467485 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFS 547
Cdd:PRK10734 199 VLANYFAISELTIGLTVIAIGTSLPELATAIAGARKGENDIAVGNIIGSNIFNIVIVLGLPALIS 263
|
|
| PLN03151 |
PLN03151 |
cation/calcium exchanger; Provisional |
924-1086 |
2.60e-07 |
|
cation/calcium exchanger; Provisional
Pssm-ID: 215604 [Multi-domain] Cd Length: 650 Bit Score: 54.77 E-value: 2.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 924 TVPDvrrQESRKFFVFTFLG----SIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGlG 999
Cdd:PLN03151 471 TEPD---RPPRRFLIPWVLGgfimSIVWFYMIANELVALLVAFGVIFGINPSILGLTVLAWGNSMGDLMSNVALAMNG-G 546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 1000 D---MAVSSSVGSNIFDITVGLPVPWLL--FSLINGLQPVPvSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTM 1074
Cdd:PLN03151 547 DgvqIAMSGCYAGPMFNTLVGLGMSMLLgaWSKSPESYMLP-EDSSLFYTMGFLVSGLIWALVVLPRNDMRPNKTLGVGL 625
|
170
....*....|..
gi 1370467485 1075 FLLYFVFLIISV 1086
Cdd:PLN03151 626 IALYLIFLTFRV 637
|
|
| PRK10734 |
PRK10734 |
putative calcium/sodium:proton antiporter; Provisional |
955-1014 |
4.44e-07 |
|
putative calcium/sodium:proton antiporter; Provisional
Pssm-ID: 182684 [Multi-domain] Cd Length: 325 Bit Score: 53.11 E-value: 4.44e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 955 MVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 1014
Cdd:PRK10734 22 LVFAASILCRTFGIPPLIIGMTVVGIGTSLPEIIVSVAASLHGQRDLAVGTALGSNITNI 81
|
|
| PLN03151 |
PLN03151 |
cation/calcium exchanger; Provisional |
453-605 |
1.90e-06 |
|
cation/calcium exchanger; Provisional
Pssm-ID: 215604 [Multi-domain] Cd Length: 650 Bit Score: 52.07 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 453 GWVVLHVFgMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSlIGVFISHS--NVGIGTIVG 530
Cdd:PLN03151 139 GYAVLGVW-LVALFYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFAS-IAAFVGKDagEVGLNSVLG 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 531 SAVFNILFVIGTCSL-FSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWN----KH 605
Cdd:PLN03151 217 GAVFVTCVVVGIVSLcVADKEVQIDKRCFIRDLCFFLFTLVSLLVILMVGKVTVGGAIAFVSIYVVYAFLVAANeilrKH 296
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
940-1022 |
3.57e-04 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 44.78 E-value: 3.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 940 TFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLG-DMAVSSSVGSNIFDITVGL 1018
Cdd:TIGR00845 758 CFVVSILMIGVLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYaDASIGNVTGSNAVNVFLGI 837
|
....
gi 1370467485 1019 PVPW 1022
Cdd:TIGR00845 838 GVAW 841
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
103-360 |
1.62e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 42.60 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 103 TLSMTVENIPSMPK-----RTAKMIPTTT----------KNNYSPTAAGTERRKEDT----PTSSRTLTYYTSTSSR--- 160
Cdd:pfam05109 388 TFDITVSGLGTAPKtliitRTATNATTTThkvifskapeSTTTSPTLNTTGFAAPNTttglPSSTHVPTNLTAPASTgpt 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 161 -QIVKKYTPTPRGEMKSYSPTqvrekvkyTPSPRGRRVGTYVPSTFMTMETSHAITPrtTVKDSDITATYKILETNSLKR 239
Cdd:pfam05109 468 vSTADVTSPTPAGTTSGASPV--------TPSPSPRDNGTESKAPDMTSPTSAVTTP--TPNATSPTPAVTTPTPNATSP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467485 240 IMEETTPTTLKgmfdSTPTfltheveANVlTSPRsvmeknnlfPPRRVESNSSAHPwgLVGKSNPKTpqgTVLLHTPATS 319
Cdd:pfam05109 538 TLGKTSPTSAV----TTPT-------PNA-TSPT---------PAVTTPTPNATIP--TLGKTSPTS---AVTTPTPNAT 591
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1370467485 320 EGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTA 360
Cdd:pfam05109 592 SPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTG 632
|
|
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