NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1207166157|ref|XP_021325950|]
View 

sickle tail protein homolog isoform X4 [Danio rerio]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
AIP3 super family cl38141
Actin interacting protein 3;
298-371 1.14e-05

Actin interacting protein 3;


The actual alignment was detected with superfamily member pfam03915:

Pssm-ID: 427585 [Multi-domain]  Cd Length: 407  Bit Score: 50.22  E-value: 1.14e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1207166157  298 YLQYGDDTKQIRMPNEITsVDTIRALFVSAFPHQLNMKMLesPstAIYVKDETRNVYYELTDVRSITDHS--CLKV 371
Cdd:pfam03915    1 FLQLGRKVKKVVLPLPLT-IASLRLLFVEKFAYSPGGDDF--P--EIYIQDPVSGVRYELEDLSDVKDGSvlSLNI 71
PHA03247 super family cl33720
large tegument protein UL36; Provisional
430-718 5.85e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 5.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  430 GMPPSPSRipfgPRNPGGGVATMPRERAGHTLPAPARASSPCPSAILERRDVKPDEDVAAktmslntraeshyADPYMLL 509
Cdd:PHA03247  2590 DAPPQSAR----PRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT-------------VPPPERP 2652
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  510 HHAPPPDTVdhAYHRATmRSYSNPSVPLEPPDHLFRQKSRNSQLPMLGSKTPPPsPHRMGEMRmvdihtvqPQSSMTLER 589
Cdd:PHA03247  2653 RDDPAPGRV--SRPRRA-RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPP-PPPTPEPA--------PHALVSATP 2720
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  590 ASPVRQSFRKEAPPMDAMVKARGGMGSPATP--DLQVHNPLAPPTDPQ-TRERMKAMEEQIASLTGLVQHALLKSNSTNS 666
Cdd:PHA03247  2721 LPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPApAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1207166157  667 NKEHSSERPVKSGSPAHSTSSTGGSPVLAPKVVAAPPERSPAPTPPLGPAPL 718
Cdd:PHA03247  2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
AIP3 super family cl33400
Actin interacting protein 3; Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in ...
641-947 3.58e-04

Actin interacting protein 3; Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in Saccharomyces cerevisiae that was previously identified as an actin-interacting protein. Actin-interacting protein 3 (Aip3p) localizes at the cell cortex where cytoskeleton assembly must be achieved to execute polarized cell growth, and deletion of AIP3 causes gross defects in cell and cytoskeletal polarity. Aip3p localization is mediated by the secretory pathway, mutations in early- or late-acting components of the secretory apparatus lead to Aip3p mislocalization.


The actual alignment was detected with superfamily member smart00806:

Pssm-ID: 214826 [Multi-domain]  Cd Length: 426  Bit Score: 45.43  E-value: 3.58e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   641 KAMEEQIASLTGLVQHALLKSNSTNSNKEHSSERPVKSgspAHSTSSTGGSPvlapkvvaaPPERSPAPTPPLGPAPLHV 720
Cdd:smart00806   81 KHIDDEIDTLQNELDEVKQALESQREAIQRLKERQQNS---AANIARPAASP---------SPVLASSSSAISLANNPDK 148
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   721 NLHLFRKNVSELRLQLQHMRQLQLQNQECVRAQIK------RAEQEIGVKLAemlrrqddpTQKQRMLVEEERHRYLSMQ 794
Cdd:smart00806  149 LNKEQRAELKSLQRELAVLRQTHNSFFTEIKESIKdilekiDKFKSSSLSAS---------GSSNRAYVESSKKKLSEDS 219
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   795 ERVLTQLGDLEQFVETLRTDsgpaASQRAVTlkevedgaVSLRK---VGENLAGLKGEFPALQSRM-------RSVLRVE 864
Cdd:smart00806  220 DSLLTKVDDLQDIIEALRKD----VAQRGVR--------PSKKQletVQKELETARKELKKMEEYIdiekpiwKKIWEAE 287
                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   865 VEAVkflKEEPHKLDSMLKRVRTLTD-------TLSNLRRCAtdnllkpTDQVCSTPPASEKPELIESPEPAPVTPQSSI 937
Cdd:smart00806  288 LDKV---CEEQQFLTLQEDLIADLKEdlekaeeTFDLVEQCC-------EEQEKGPSKNRNKPVSLPVPTPGTFNDLKDQ 357
                           330
                    ....*....|
gi 1207166157   938 VRSEVMTSNP 947
Cdd:smart00806  358 VLMEVRALKP 367
 
Name Accession Description Interval E-value
AIP3 pfam03915
Actin interacting protein 3;
298-371 1.14e-05

Actin interacting protein 3;


Pssm-ID: 427585 [Multi-domain]  Cd Length: 407  Bit Score: 50.22  E-value: 1.14e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1207166157  298 YLQYGDDTKQIRMPNEITsVDTIRALFVSAFPHQLNMKMLesPstAIYVKDETRNVYYELTDVRSITDHS--CLKV 371
Cdd:pfam03915    1 FLQLGRKVKKVVLPLPLT-IASLRLLFVEKFAYSPGGDDF--P--EIYIQDPVSGVRYELEDLSDVKDGSvlSLNI 71
PHA03247 PHA03247
large tegument protein UL36; Provisional
430-718 5.85e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 5.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  430 GMPPSPSRipfgPRNPGGGVATMPRERAGHTLPAPARASSPCPSAILERRDVKPDEDVAAktmslntraeshyADPYMLL 509
Cdd:PHA03247  2590 DAPPQSAR----PRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT-------------VPPPERP 2652
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  510 HHAPPPDTVdhAYHRATmRSYSNPSVPLEPPDHLFRQKSRNSQLPMLGSKTPPPsPHRMGEMRmvdihtvqPQSSMTLER 589
Cdd:PHA03247  2653 RDDPAPGRV--SRPRRA-RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPP-PPPTPEPA--------PHALVSATP 2720
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  590 ASPVRQSFRKEAPPMDAMVKARGGMGSPATP--DLQVHNPLAPPTDPQ-TRERMKAMEEQIASLTGLVQHALLKSNSTNS 666
Cdd:PHA03247  2721 LPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPApAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1207166157  667 NKEHSSERPVKSGSPAHSTSSTGGSPVLAPKVVAAPPERSPAPTPPLGPAPL 718
Cdd:PHA03247  2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
AIP3 smart00806
Actin interacting protein 3; Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in ...
641-947 3.58e-04

Actin interacting protein 3; Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in Saccharomyces cerevisiae that was previously identified as an actin-interacting protein. Actin-interacting protein 3 (Aip3p) localizes at the cell cortex where cytoskeleton assembly must be achieved to execute polarized cell growth, and deletion of AIP3 causes gross defects in cell and cytoskeletal polarity. Aip3p localization is mediated by the secretory pathway, mutations in early- or late-acting components of the secretory apparatus lead to Aip3p mislocalization.


Pssm-ID: 214826 [Multi-domain]  Cd Length: 426  Bit Score: 45.43  E-value: 3.58e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   641 KAMEEQIASLTGLVQHALLKSNSTNSNKEHSSERPVKSgspAHSTSSTGGSPvlapkvvaaPPERSPAPTPPLGPAPLHV 720
Cdd:smart00806   81 KHIDDEIDTLQNELDEVKQALESQREAIQRLKERQQNS---AANIARPAASP---------SPVLASSSSAISLANNPDK 148
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   721 NLHLFRKNVSELRLQLQHMRQLQLQNQECVRAQIK------RAEQEIGVKLAemlrrqddpTQKQRMLVEEERHRYLSMQ 794
Cdd:smart00806  149 LNKEQRAELKSLQRELAVLRQTHNSFFTEIKESIKdilekiDKFKSSSLSAS---------GSSNRAYVESSKKKLSEDS 219
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   795 ERVLTQLGDLEQFVETLRTDsgpaASQRAVTlkevedgaVSLRK---VGENLAGLKGEFPALQSRM-------RSVLRVE 864
Cdd:smart00806  220 DSLLTKVDDLQDIIEALRKD----VAQRGVR--------PSKKQletVQKELETARKELKKMEEYIdiekpiwKKIWEAE 287
                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   865 VEAVkflKEEPHKLDSMLKRVRTLTD-------TLSNLRRCAtdnllkpTDQVCSTPPASEKPELIESPEPAPVTPQSSI 937
Cdd:smart00806  288 LDKV---CEEQQFLTLQEDLIADLKEdlekaeeTFDLVEQCC-------EEQEKGPSKNRNKPVSLPVPTPGTFNDLKDQ 357
                           330
                    ....*....|
gi 1207166157   938 VRSEVMTSNP 947
Cdd:smart00806  358 VLMEVRALKP 367
 
Name Accession Description Interval E-value
AIP3 pfam03915
Actin interacting protein 3;
298-371 1.14e-05

Actin interacting protein 3;


Pssm-ID: 427585 [Multi-domain]  Cd Length: 407  Bit Score: 50.22  E-value: 1.14e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1207166157  298 YLQYGDDTKQIRMPNEITsVDTIRALFVSAFPHQLNMKMLesPstAIYVKDETRNVYYELTDVRSITDHS--CLKV 371
Cdd:pfam03915    1 FLQLGRKVKKVVLPLPLT-IASLRLLFVEKFAYSPGGDDF--P--EIYIQDPVSGVRYELEDLSDVKDGSvlSLNI 71
PHA03247 PHA03247
large tegument protein UL36; Provisional
430-718 5.85e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 5.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  430 GMPPSPSRipfgPRNPGGGVATMPRERAGHTLPAPARASSPCPSAILERRDVKPDEDVAAktmslntraeshyADPYMLL 509
Cdd:PHA03247  2590 DAPPQSAR----PRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT-------------VPPPERP 2652
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  510 HHAPPPDTVdhAYHRATmRSYSNPSVPLEPPDHLFRQKSRNSQLPMLGSKTPPPsPHRMGEMRmvdihtvqPQSSMTLER 589
Cdd:PHA03247  2653 RDDPAPGRV--SRPRRA-RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPP-PPPTPEPA--------PHALVSATP 2720
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  590 ASPVRQSFRKEAPPMDAMVKARGGMGSPATP--DLQVHNPLAPPTDPQ-TRERMKAMEEQIASLTGLVQHALLKSNSTNS 666
Cdd:PHA03247  2721 LPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPApAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1207166157  667 NKEHSSERPVKSGSPAHSTSSTGGSPVLAPKVVAAPPERSPAPTPPLGPAPL 718
Cdd:PHA03247  2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
PHA03247 PHA03247
large tegument protein UL36; Provisional
422-717 1.02e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 1.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  422 SMSPTTPHGMPPSPSRIPFGPRNPGGGVATMPRERAGHTLPAPARASSPCPSAILER--RDVKPDEDVAAKTMSLNTRAE 499
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRaaQASSPPQRPRRRAARPTVGSL 2695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  500 SHYADPymllhhAPPPDTVDHAYHRATmrsysnPSVPLEPPDHLFRQKSrnsqlPMLGSKTPPPSPHRMGEMRMVDIHTV 579
Cdd:PHA03247  2696 TSLADP------PPPPPTPEPAPHALV------SATPLPPGPAAARQAS-----PALPAAPAPPAVPAGPATPGGPARPA 2758
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  580 QPQSSMTLERASPVRQsfrKEAPPMDAMVKARGGMGSPATPDLQVHNPLAPPTDPQTrermkameEQIASLTGLVQHALL 659
Cdd:PHA03247  2759 RPPTTAGPPAPAPPAA---PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVL--------APAAALPPAASPAGP 2827
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1207166157  660 KSNSTNSnkehSSERPVKSGSPAHSTSSTGGSPVLAPKVVAAPPERSPAPTPPLGPAP 717
Cdd:PHA03247  2828 LPPPTSA----QPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARP 2881
AIP3 smart00806
Actin interacting protein 3; Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in ...
641-947 3.58e-04

Actin interacting protein 3; Aip3p/Bud6p is a regulator of cell and cytoskeletal polarity in Saccharomyces cerevisiae that was previously identified as an actin-interacting protein. Actin-interacting protein 3 (Aip3p) localizes at the cell cortex where cytoskeleton assembly must be achieved to execute polarized cell growth, and deletion of AIP3 causes gross defects in cell and cytoskeletal polarity. Aip3p localization is mediated by the secretory pathway, mutations in early- or late-acting components of the secretory apparatus lead to Aip3p mislocalization.


Pssm-ID: 214826 [Multi-domain]  Cd Length: 426  Bit Score: 45.43  E-value: 3.58e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   641 KAMEEQIASLTGLVQHALLKSNSTNSNKEHSSERPVKSgspAHSTSSTGGSPvlapkvvaaPPERSPAPTPPLGPAPLHV 720
Cdd:smart00806   81 KHIDDEIDTLQNELDEVKQALESQREAIQRLKERQQNS---AANIARPAASP---------SPVLASSSSAISLANNPDK 148
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   721 NLHLFRKNVSELRLQLQHMRQLQLQNQECVRAQIK------RAEQEIGVKLAemlrrqddpTQKQRMLVEEERHRYLSMQ 794
Cdd:smart00806  149 LNKEQRAELKSLQRELAVLRQTHNSFFTEIKESIKdilekiDKFKSSSLSAS---------GSSNRAYVESSKKKLSEDS 219
                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   795 ERVLTQLGDLEQFVETLRTDsgpaASQRAVTlkevedgaVSLRK---VGENLAGLKGEFPALQSRM-------RSVLRVE 864
Cdd:smart00806  220 DSLLTKVDDLQDIIEALRKD----VAQRGVR--------PSKKQletVQKELETARKELKKMEEYIdiekpiwKKIWEAE 287
                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157   865 VEAVkflKEEPHKLDSMLKRVRTLTD-------TLSNLRRCAtdnllkpTDQVCSTPPASEKPELIESPEPAPVTPQSSI 937
Cdd:smart00806  288 LDKV---CEEQQFLTLQEDLIADLKEdlekaeeTFDLVEQCC-------EEQEKGPSKNRNKPVSLPVPTPGTFNDLKDQ 357
                           330
                    ....*....|
gi 1207166157   938 VRSEVMTSNP 947
Cdd:smart00806  358 VLMEVRALKP 367
PHA03247 PHA03247
large tegument protein UL36; Provisional
418-722 5.54e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 5.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  418 HMQGSMSPTTPHGMPPSPSRIPFGP---RNPGGGVATMPreraghtlPAPARASSPCPsAILErrDVKPDEDVAAKTMS- 493
Cdd:PHA03247  2468 LLLGELFPGAPVYRRPAEARFPFAAgaaPDPGGGGPPDP--------DAPPAPSRLAP-AILP--DEPVGEPVHPRMLTw 2536
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  494 ---LNTRAESHYADPYMLLHHAPPPDTVDHAY------------------HRATMRSYSN-PSVPLEPPDHlFRQKSRNS 551
Cdd:PHA03247  2537 irgLEELASDDAGDPPPPLPPAAPPAAPDRSVppprpaprpsepavtsraRRPDAPPQSArPRAPVDDRGD-PRGPAPPS 2615
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  552 QLPMLGSKTPPPSPHR-------MGEMRMVDIHTVQPQSSMTLERASPVRQSFRKEAPPMDAMVKAR---GGMGSPATPD 621
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPspaanepDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRprrRAARPTVGSL 2695
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  622 LQVHNPLAPPTDPQTRERMKAMEEQIASLTGLVQHALLKSNSTNSNKEhSSERPVKSGSPAHSTSSTGGSPVLAPKVVAA 701
Cdd:PHA03247  2696 TSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA-VPAGPATPGGPARPARPPTTAGPPAPAPPAA 2774
                          330       340
                   ....*....|....*....|.
gi 1207166157  702 PPERSPAPTPPLGPAPLHVNL 722
Cdd:PHA03247  2775 PAAGPPRRLTRPAVASLSESR 2795
PHA03247 PHA03247
large tegument protein UL36; Provisional
377-717 6.07e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 6.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  377 AHAFSHGPRPSNGDTRVHREMIFAgrDGHPLRNPPMGPPPPHMQGSMSPTTPHG---------MPPSPSRIPFGPRNPgG 447
Cdd:PHA03247  2676 ASSPPQRPRRRAARPTVGSLTSLA--DPPPPPPTPEPAPHALVSATPLPPGPAAarqaspalpAAPAPPAVPAGPATP-G 2752
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  448 GVATMPRERAGHTLPAPARASSPCPSAilERRDVKPdedvAAKTMSLNTRAESHYADPymllhhAPPPDTVDHAyhRATM 527
Cdd:PHA03247  2753 GPARPARPPTTAGPPAPAPPAAPAAGP--PRRLTRP----AVASLSESRESLPSPWDP------ADPPAAVLAP--AAAL 2818
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  528 RSYSNPSVPLEPPdhlfrqksrNSQLPMLGSKTPPPSPHRMGEMrmvdiHTVQPQSSmtLERASPVRQSFRKEAPPMDAM 607
Cdd:PHA03247  2819 PPAASPAGPLPPP---------TSAQPTAPPPPPGPPPPSLPLG-----GSVAPGGD--VRRRPPSRSPAAKPAAPARPP 2882
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  608 VKArggMGSPATPdlQVHNPLAPPTDPQTRERMKAMEEQIASLTGLVQHALLKSNSTNSNKEHSSERPVKSGSPAHSTSS 687
Cdd:PHA03247  2883 VRR---LARPAVS--RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
                          330       340       350
                   ....*....|....*....|....*....|...
gi 1207166157  688 TGGSP---VLAPKVVAAPPERSPAPTPPLgPAP 717
Cdd:PHA03247  2958 AVPQPwlgALVPGRVAVPRFRVPQPAPSR-EAP 2989
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
421-718 9.02e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 9.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  421 GSMSPTTPHGMPPSPSRIPFGPRNPGGGVATMPRERAGHTlPAPARASSPCPSAILERRDVKPDEDVAAKtmslNTRAES 500
Cdd:PHA03307    90 WSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPS-PAPDLSEMLRPVGSPGPPPAASPPAAGAS----PAAVAS 164
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  501 HYADPymlLHHAPPPDTVDhayhrATMRSYSNPS---VPLEPPDHLFRQKSRNSQLPMLGSKTPPPSPHRMGEMRmvdih 577
Cdd:PHA03307   165 DAASS---RQAALPLSSPE-----ETARAPSSPPaepPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADD----- 231
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207166157  578 tvQPQSSMTleraSPVRQSFRKEAPPMDAMVKARGGMGSPATPDLQVHNPLAPPTDPQTRERMKAMEEQIASLTGLVQHA 657
Cdd:PHA03307   232 --AGASSSD----SSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGS 305
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1207166157  658 LLKSNSTNSNKEHSSERPVKSGSPAHSTSSTGGSPVlapkvvAAPPERSPAPTPPLGPAPL 718
Cdd:PHA03307   306 GPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAV------SPGPSPSRSPSPSRPPPPA 360
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure