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Conserved domains on  [gi|1207163939|ref|XP_021325432|]
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solute carrier family 34 member 2b isoform X1 [Danio rerio]

Protein Classification

sodium-dependent phosphate transport protein 2( domain architecture ID 11490082)

sodium-dependent phosphate transport protein 2 may be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
90-585 4.16e-162

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 472.42  E-value: 4.16e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939  90 YMFVCSLDILSSAFQLVGGKAAGDIFKDNAVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVSSGLLEVKSAVPIIMGA 169
Cdd:TIGR01013   5 FVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPLIMGA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 170 NIGTSVTNTIVAVMQAGDRNEFRRAFAGATVHDFFNWLSVLVLLPLEVASGMLYRLTKLVIDSFNIQTGADAPDLLKVIT 249
Cdd:TIGR01013  85 NIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLLNSLT 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 250 EPLTKNIIELDTSVIRDIAtgdpAARNKSLIKIWCKTEKitnlvnvtvpgianctpdALCWVDGDLIWTQknqtdtiylk 329
Cdd:TIGR01013 165 APATALIVQLDNLIIRLIG----SLLILPLIDILASTLS------------------SLPVPESNLPIEA---------- 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 330 kctHMFVfadlpdlAVGLILLALSLLALCTCLILIVKLLNSMLKGQVAVVIKKVLNTDFPFPFAWVTGYLAILVGAGMTF 409
Cdd:TIGR01013 213 ---HIFV-------NVGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTF 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 410 IVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPGETLANSLQISLCHFFFNIAGILLWYPIPFT 489
Cdd:TIGR01013 283 IIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCT 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 490 RVPIRLAKALGNRTAKYRWFAGLYLILCFLLFPLTVLGLSIAGWQVLVGVGVPVLVLAIFVIVVNVMQKRCPRflPSFIR 569
Cdd:TIGR01013 363 RKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQ 440
                         490
                  ....*....|....*.
gi 1207163939 570 SWEFLPKPLHSLKPWD 585
Cdd:TIGR01013 441 TWSFLPDWLRSLKRLD 456
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
90-585 4.16e-162

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 472.42  E-value: 4.16e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939  90 YMFVCSLDILSSAFQLVGGKAAGDIFKDNAVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVSSGLLEVKSAVPIIMGA 169
Cdd:TIGR01013   5 FVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPLIMGA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 170 NIGTSVTNTIVAVMQAGDRNEFRRAFAGATVHDFFNWLSVLVLLPLEVASGMLYRLTKLVIDSFNIQTGADAPDLLKVIT 249
Cdd:TIGR01013  85 NIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLLNSLT 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 250 EPLTKNIIELDTSVIRDIAtgdpAARNKSLIKIWCKTEKitnlvnvtvpgianctpdALCWVDGDLIWTQknqtdtiylk 329
Cdd:TIGR01013 165 APATALIVQLDNLIIRLIG----SLLILPLIDILASTLS------------------SLPVPESNLPIEA---------- 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 330 kctHMFVfadlpdlAVGLILLALSLLALCTCLILIVKLLNSMLKGQVAVVIKKVLNTDFPFPFAWVTGYLAILVGAGMTF 409
Cdd:TIGR01013 213 ---HIFV-------NVGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTF 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 410 IVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPGETLANSLQISLCHFFFNIAGILLWYPIPFT 489
Cdd:TIGR01013 283 IIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCT 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 490 RVPIRLAKALGNRTAKYRWFAGLYLILCFLLFPLTVLGLSIAGWQVLVGVGVPVLVLAIFVIVVNVMQKRCPRflPSFIR 569
Cdd:TIGR01013 363 RKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQ 440
                         490
                  ....*....|....*.
gi 1207163939 570 SWEFLPKPLHSLKPWD 585
Cdd:TIGR01013 441 TWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
399-524 2.09e-19

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 92.16  E-value: 2.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 399 LAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPgetlANSLQISLCHFFFNIA 478
Cdd:COG1283   176 LGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGTTITALLASIGAN----VAARRAALAHLLFNLI 251
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1207163939 479 GILLWYPI--PFTRVPIRLAKALGNRTAkyrWFAGLY-LILCFLLFPLT 524
Cdd:COG1283   252 GVLIFLPLlpPFAALVAWLSPDPARQIA---NFHTLFnLLNALLFLPFI 297
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
398-455 6.15e-13

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 66.27  E-value: 6.15e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1207163939 398 YLAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAM 455
Cdd:pfam02690  33 LKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
398-521 1.12e-10

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 63.00  E-value: 1.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 398 YLAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPGEtlanSLQISLCHFFFNI 477
Cdd:NF037997  165 LLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSGKE----AKLTAYAHIWLNV 240
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1207163939 478 AGILLWYPI--PFTRVPIRLAKALGNRTAKyrwFAGLYLILCFLLF 521
Cdd:NF037997  241 LGVLLFLPFihLLGEFVALLASSPDVQLAH---ASVLFNVISSLLV 283
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
400-450 2.47e-03

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 40.28  E-value: 2.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1207163939 400 AILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTA 450
Cdd:NF037997   41 GFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTT 91
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
90-585 4.16e-162

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 472.42  E-value: 4.16e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939  90 YMFVCSLDILSSAFQLVGGKAAGDIFKDNAVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVSSGLLEVKSAVPIIMGA 169
Cdd:TIGR01013   5 FVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPLIMGA 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 170 NIGTSVTNTIVAVMQAGDRNEFRRAFAGATVHDFFNWLSVLVLLPLEVASGMLYRLTKLVIDSFNIQTGADAPDLLKVIT 249
Cdd:TIGR01013  85 NIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLLNSLT 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 250 EPLTKNIIELDTSVIRDIAtgdpAARNKSLIKIWCKTEKitnlvnvtvpgianctpdALCWVDGDLIWTQknqtdtiylk 329
Cdd:TIGR01013 165 APATALIVQLDNLIIRLIG----SLLILPLIDILASTLS------------------SLPVPESNLPIEA---------- 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 330 kctHMFVfadlpdlAVGLILLALSLLALCTCLILIVKLLNSMLKGQVAVVIKKVLNTDFPFPFAWVTGYLAILVGAGMTF 409
Cdd:TIGR01013 213 ---HIFV-------NVGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGDAMTF 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 410 IVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPGETLANSLQISLCHFFFNIAGILLWYPIPFT 489
Cdd:TIGR01013 283 IIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYPLPCT 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 490 RVPIRLAKALGNRTAKYRWFAGLYLILCFLLFPLTVLGLSIAGWQVLVGVGVPVLVLAIFVIVVNVMQKRCPRflPSFIR 569
Cdd:TIGR01013 363 RKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--PQSLQ 440
                         490
                  ....*....|....*.
gi 1207163939 570 SWEFLPKPLHSLKPWD 585
Cdd:TIGR01013 441 TWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
399-524 2.09e-19

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 92.16  E-value: 2.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 399 LAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPgetlANSLQISLCHFFFNIA 478
Cdd:COG1283   176 LGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGTTITALLASIGAN----VAARRAALAHLLFNLI 251
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1207163939 479 GILLWYPI--PFTRVPIRLAKALGNRTAkyrWFAGLY-LILCFLLFPLT 524
Cdd:COG1283   252 GVLIFLPLlpPFAALVAWLSPDPARQIA---NFHTLFnLLNALLFLPFI 297
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
398-455 6.15e-13

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 66.27  E-value: 6.15e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1207163939 398 YLAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAM 455
Cdd:pfam02690  33 LKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
398-521 1.12e-10

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 63.00  E-value: 1.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 398 YLAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAAMASPGEtlanSLQISLCHFFFNI 477
Cdd:NF037997  165 LLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSGKE----AKLTAYAHIWLNV 240
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1207163939 478 AGILLWYPI--PFTRVPIRLAKALGNRTAKyrwFAGLYLILCFLLF 521
Cdd:NF037997  241 LGVLLFLPFihLLGEFVALLASSPDVQLAH---ASVLFNVISSLLV 283
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
91-182 2.26e-08

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 53.17  E-value: 2.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939  91 MFVCSLDILSSAFQlvggKAAGDIFKD--NAVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVSSGLLEVKSAVPIIMG 168
Cdd:pfam02690   1 LFLFGMKLMSDGLQ----KLAGGRLRRilEKLTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMG 76
                          90
                  ....*....|....
gi 1207163939 169 ANIGTSVTNTIVAV 182
Cdd:pfam02690  77 ANIGTTVTAQLIAF 90
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
399-454 2.66e-08

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 56.73  E-value: 2.66e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1207163939 399 LAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTAILAA 454
Cdd:COG1283    49 KGVLAGALVTALLQSSSATTVMVVGFVNAGLMTLAQALGVILGANIGTTLTAQLIA 104
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
360-524 1.98e-06

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 49.92  E-value: 1.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 360 CLILIVKLLNSMLKGQVAVVIKKVLNTDFpfpfawvtgYLAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLT 439
Cdd:TIGR00704 143 AIEGFSHAAGPITKAKGGADIFAHLNDDI---------LLAALIGAMFAAIIHSSLAAIGILASFMAAGIIGFPQALCLV 213
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1207163939 440 LGSNIGTTTTAILAAMASPgetlANSLQISLCHFFFNIAGILLWYPIpFTRVPIRLAKALGNRTAKYRWFAGLY-LILCF 518
Cdd:TIGR00704 214 IGANIGSCILAMLAASAAG----AAAKQTALAHLLFKLLGSAIILPF-LHAAAEFMEKLSLDKAEKIAHFHLFFnLVRAL 288

                  ....*.
gi 1207163939 519 LLFPLT 524
Cdd:TIGR00704 289 LFLPFT 294
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
399-450 7.00e-05

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 45.30  E-value: 7.00e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1207163939 399 LAILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTA 450
Cdd:TIGR00704  46 KAFCAGIGFTAILQSSNAFMMIVIGFVAADLLAFAPAIPIILGADVGSAFMA 97
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
155-215 6.17e-04

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 42.86  E-value: 6.17e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1207163939 155 GLLEVKSAVPIIMGANIGTSVTnTIVAVMqAGDRNEfRRAfagATVHDFFNWLSVLVLLPL 215
Cdd:COG1283   205 GLIPLEAALALVLGANIGTTIT-ALLASI-GANVAA-RRA---ALAHLLFNLIGVLIFLPL 259
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
400-450 2.47e-03

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 40.28  E-value: 2.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1207163939 400 AILVGAGMTFIVQSSSVFTSAITPLVGIGVISLERAYPLTLGSNIGTTTTA 450
Cdd:NF037997   41 GFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTT 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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