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Conserved domains on  [gi|1207128882|ref|XP_021322927|]
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inverted formin-2 [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Drf_FH3 super family cl05717
Diaphanous FH3 Domain; This region is found in the Formin-like and and diaphanous proteins.
 160-226 1.17e-10

Diaphanous FH3 Domain; This region is found in the Formin-like and and diaphanous proteins.


The actual alignment was detected with superfamily member pfam06367:

Pssm-ID: 461885 [Multi-domain]  Cd Length: 195  Bit Score: 58.82  E-value: 1.17e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207128882 160 EGHRLALDALEHYKCVKTQQYRFSVIMNELRST--DNVPYMVTLLSVINALIFSADGLQQRDKMRKEFI 226
Cdd:pfam06367   1 GGHEKVLEATLNFKEVCRERGRFQSLVGALDSSenDNVEYKVATMQFINALVNSPEDLQFRLHLRSEFT 69
Drf_GBD super family cl05720
Diaphanous GTPase-binding Domain; This domain is bound to by GTP-attached Rho proteins, ...
 98-154 4.18e-05

Diaphanous GTPase-binding Domain; This domain is bound to by GTP-attached Rho proteins, leading to activation of the Drf protein.


The actual alignment was detected with superfamily member pfam06371:

Pssm-ID: 461886  Cd Length: 188  Bit Score: 43.07  E-value: 4.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207128882  98 DALLQLTCVSCVRAVMNSSAGIHFIVDNEGYVRKLSQALDTSNTMVKKQVFELLAAL 154
Cdd:pfam06371 130 DLDREYEILKCLKALMNNKFGLDHVLGHPSSIDLLVQSLDSERLKTRKLVLELLTAL 186
 
Name Accession Description Interval E-value
Drf_FH3 pfam06367
Diaphanous FH3 Domain; This region is found in the Formin-like and and diaphanous proteins.
 160-226 1.17e-10

Diaphanous FH3 Domain; This region is found in the Formin-like and and diaphanous proteins.


Pssm-ID: 461885 [Multi-domain]  Cd Length: 195  Bit Score: 58.82  E-value: 1.17e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207128882 160 EGHRLALDALEHYKCVKTQQYRFSVIMNELRST--DNVPYMVTLLSVINALIFSADGLQQRDKMRKEFI 226
Cdd:pfam06367   1 GGHEKVLEATLNFKEVCRERGRFQSLVGALDSSenDNVEYKVATMQFINALVNSPEDLQFRLHLRSEFT 69
Drf_GBD pfam06371
Diaphanous GTPase-binding Domain; This domain is bound to by GTP-attached Rho proteins, ...
 98-154 4.18e-05

Diaphanous GTPase-binding Domain; This domain is bound to by GTP-attached Rho proteins, leading to activation of the Drf protein.


Pssm-ID: 461886  Cd Length: 188  Bit Score: 43.07  E-value: 4.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207128882  98 DALLQLTCVSCVRAVMNSSAGIHFIVDNEGYVRKLSQALDTSNTMVKKQVFELLAAL 154
Cdd:pfam06371 130 DLDREYEILKCLKALMNNKFGLDHVLGHPSSIDLLVQSLDSERLKTRKLVLELLTAL 186
 
Name Accession Description Interval E-value
Drf_FH3 pfam06367
Diaphanous FH3 Domain; This region is found in the Formin-like and and diaphanous proteins.
 160-226 1.17e-10

Diaphanous FH3 Domain; This region is found in the Formin-like and and diaphanous proteins.


Pssm-ID: 461885 [Multi-domain]  Cd Length: 195  Bit Score: 58.82  E-value: 1.17e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1207128882 160 EGHRLALDALEHYKCVKTQQYRFSVIMNELRST--DNVPYMVTLLSVINALIFSADGLQQRDKMRKEFI 226
Cdd:pfam06367   1 GGHEKVLEATLNFKEVCRERGRFQSLVGALDSSenDNVEYKVATMQFINALVNSPEDLQFRLHLRSEFT 69
Drf_GBD pfam06371
Diaphanous GTPase-binding Domain; This domain is bound to by GTP-attached Rho proteins, ...
 98-154 4.18e-05

Diaphanous GTPase-binding Domain; This domain is bound to by GTP-attached Rho proteins, leading to activation of the Drf protein.


Pssm-ID: 461886  Cd Length: 188  Bit Score: 43.07  E-value: 4.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1207128882  98 DALLQLTCVSCVRAVMNSSAGIHFIVDNEGYVRKLSQALDTSNTMVKKQVFELLAAL 154
Cdd:pfam06371 130 DLDREYEILKCLKALMNNKFGLDHVLGHPSSIDLLVQSLDSERLKTRKLVLELLTAL 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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