|
Name |
Accession |
Description |
Interval |
E-value |
| GcvT |
COG0404 |
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ... |
277-691 |
1.64e-87 |
|
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage
:
Pssm-ID: 440173 [Multi-domain] Cd Length: 372 Bit Score: 279.27 E-value: 1.64e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 277 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVppnkdllaleqsktfykpdwfDIVESEVKCCKEAVCVIDMSSFTKFE 356
Cdd:COG0404 1 FRPLRRTPLHDRHVALGAKFVDFGGWEMPVQYP---------------------GGVIAEHLAVREAVGLFDVSHMGKIE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 357 ITstGDQALESLQYLFSNDLDV-PVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLPKDSNL 435
Cdd:COG0404 60 VT--GPDAAAFLDRLVTNDVSKlKPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEEHLPPDFDV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 436 LLEDVTWKYTALNLIGPRAVDVLSELsyAPMTPDHFPTLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNE 515
Cdd:COG0404 138 TITDVTDDWALLAVQGPKAREVLAKL--TDADLSALPFMSFREGTVAGVP-VRVSRTGYTGEDGFEIYVPAEDAEALWDA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 516 VMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGiDFIGRDALLQQKQTGVYKRLVMFIL 595
Cdd:COG0404 215 LLEAGEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 596 DDHDTdldlwPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEeqvvtadfinrgEYEIDIAGHRFQAK 675
Cdd:COG0404 294 DGRGV-----PRAGAPVLADGEVVGEVTSGTFSPTLGKSIALAYVPAGLARPGT------------ELEVEIRGKRVPAE 356
|
410
....*....|....*.
gi 1046870090 676 AKLYPvtsFFTHKRRK 691
Cdd:COG0404 357 VVKPP---FYDPEGER 369
|
|
| DadA |
COG0665 |
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]; |
1-242 |
6.46e-21 |
|
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
:
Pssm-ID: 440429 [Multi-domain] Cd Length: 364 Bit Score: 94.97 E-value: 6.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 1 MHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLTKKGRVTGVDTDKGQIECQYFVNCAGQWAYELGlsSEEPVS 80
Cdd:COG0665 140 LYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLL--PMLGLR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 81 IPLHACEHFYLLTRPCDAPLqssTPTVVDaDGRIYIRNWQGG--VLSGGFEKNPkpiftegknqleiQNLREDWDHFEPL 158
Cdd:COG0665 218 LPLRPVRGYVLVTEPLPDLP---LRPVLD-DTGVYLRPTADGrlLVGGTAEPAG-------------FDRAPTPERLEAL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 159 LSSLLRRMPGLESVEILKLVNCPETFTADMKCIMGESPVVQGYFVLAGMNsaglslgggagkllAEWMVYGYPSENVWEL 238
Cdd:COG0665 281 LRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGghgvtlapaagrllADLILGGEPPLDLAPF 360
|
....
gi 1046870090 239 DLQR 242
Cdd:COG0665 361 SPDR 364
|
|
| FAO_M |
pfam16350 |
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ... |
229-283 |
6.14e-16 |
|
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).
:
Pssm-ID: 465100 Cd Length: 56 Bit Score: 72.10 E-value: 6.14e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046870090 229 GYPSENVWELDLQRFGALQGSRTFLRHRVMEVMPLIYDLKVPRWDFQTGRQLRTS 283
Cdd:pfam16350 2 GEPPIDLWECDIRRFGPHQNNREYLRERVAENYGEVYDIHHPNEEREAGRPLRTS 56
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GcvT |
COG0404 |
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ... |
277-691 |
1.64e-87 |
|
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440173 [Multi-domain] Cd Length: 372 Bit Score: 279.27 E-value: 1.64e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 277 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVppnkdllaleqsktfykpdwfDIVESEVKCCKEAVCVIDMSSFTKFE 356
Cdd:COG0404 1 FRPLRRTPLHDRHVALGAKFVDFGGWEMPVQYP---------------------GGVIAEHLAVREAVGLFDVSHMGKIE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 357 ITstGDQALESLQYLFSNDLDV-PVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLPKDSNL 435
Cdd:COG0404 60 VT--GPDAAAFLDRLVTNDVSKlKPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEEHLPPDFDV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 436 LLEDVTWKYTALNLIGPRAVDVLSELsyAPMTPDHFPTLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNE 515
Cdd:COG0404 138 TITDVTDDWALLAVQGPKAREVLAKL--TDADLSALPFMSFREGTVAGVP-VRVSRTGYTGEDGFEIYVPAEDAEALWDA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 516 VMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGiDFIGRDALLQQKQTGVYKRLVMFIL 595
Cdd:COG0404 215 LLEAGEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 596 DDHDTdldlwPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEeqvvtadfinrgEYEIDIAGHRFQAK 675
Cdd:COG0404 294 DGRGV-----PRAGAPVLADGEVVGEVTSGTFSPTLGKSIALAYVPAGLARPGT------------ELEVEIRGKRVPAE 356
|
410
....*....|....*.
gi 1046870090 676 AKLYPvtsFFTHKRRK 691
Cdd:COG0404 357 VVKPP---FYDPEGER 369
|
|
| GCV_T |
pfam01571 |
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ... |
286-559 |
3.05e-82 |
|
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 460255 Cd Length: 254 Bit Score: 260.98 E-value: 3.05e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 286 YDRLDAQGARWMEKHGFERPKYFVPPNKDllaleqsktfykpdwfdiveSEVKCCKEAVCVIDMSSFTKFEITstGDQAL 365
Cdd:pfam01571 1 YDRHVALGAKFVEFAGWEMPVQYGSNGIL--------------------AEHRAVREAAGLFDVSHMGKIEVS--GPDAA 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 366 ESLQYLFSNDLD-VPVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLPKDsNLLLEDVTWKY 444
Cdd:pfam01571 59 AFLQRLTTNDVSkLKPGRATYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHAEKL-DVVVVDVTDDY 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 445 TALNLIGPRAVDVLSELSYAPMTPDhFPTLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYG 524
Cdd:pfam01571 138 ALLALQGPKAREVLEKLTDGDLLEA-LPFFSFREIEIGGVP-VRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELG 215
|
250 260 270
....*....|....*....|....*....|....*
gi 1046870090 525 IRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECG 559
Cdd:pfam01571 216 LRPAGLGARDSLRLEAGLPLYGHDLDEETTPLEAG 250
|
|
| gcvT |
PRK00389 |
glycine cleavage system aminomethyltransferase GcvT; |
280-640 |
3.68e-38 |
|
glycine cleavage system aminomethyltransferase GcvT;
Pssm-ID: 234742 [Multi-domain] Cd Length: 359 Bit Score: 145.26 E-value: 3.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 280 LRTSPLYDRLDAQGARWMEKHGFERP-KYfvppnkdllaleQSktfykpdwfdIVEsEVKCCKEAVCVIDMSSFTKFEIT 358
Cdd:PRK00389 2 LKRTPLYDLHVALGAKMVDFGGWEMPvQY------------GS----------IIE-EHHAVRTDAGLFDVSHMGEVDVT 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 359 stGDQALESLQYLFSNDLD-VPVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMI--SPTDQQVhcWAWLHKYLpKDSNL 435
Cdd:PRK00389 59 --GPDALAFLQYLLANDVSkLKPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVvnAANREKD--LAWIKSHA-AGFGV 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 436 LLEDVTWKYTALNLIGPRAVDVLSELSYAPMtpDHFPTLFCKEMSVGYANGIRVmSMT-HTGEPGFMLYIPIEYALHVYN 514
Cdd:PRK00389 134 EVTDRSDDLAMIAVQGPKAREKLQKLTDADL--SELKPFFGAQGAEVGGGDVLV-ARTgYTGEDGFEIYLPAEDAEALWD 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 515 EVMSVGqkygIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIGRDALLQQKQTGVYKRLVMF- 593
Cdd:PRK00389 211 ALLEAG----VKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEEKRDFIGREALEAQKEAGVERKLVGLe 286
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1046870090 594 -----IlddhdtdldlwPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYV 640
Cdd:PRK00389 287 leergI-----------PRHGYPVLADGEEIGEVTSGTFSPTLGKSIALAYV 327
|
|
| DadA |
COG0665 |
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]; |
1-242 |
6.46e-21 |
|
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
Pssm-ID: 440429 [Multi-domain] Cd Length: 364 Bit Score: 94.97 E-value: 6.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 1 MHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLTKKGRVTGVDTDKGQIECQYFVNCAGQWAYELGlsSEEPVS 80
Cdd:COG0665 140 LYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLL--PMLGLR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 81 IPLHACEHFYLLTRPCDAPLqssTPTVVDaDGRIYIRNWQGG--VLSGGFEKNPkpiftegknqleiQNLREDWDHFEPL 158
Cdd:COG0665 218 LPLRPVRGYVLVTEPLPDLP---LRPVLD-DTGVYLRPTADGrlLVGGTAEPAG-------------FDRAPTPERLEAL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 159 LSSLLRRMPGLESVEILKLVNCPETFTADMKCIMGESPVVQGYFVLAGMNsaglslgggagkllAEWMVYGYPSENVWEL 238
Cdd:COG0665 281 LRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGghgvtlapaagrllADLILGGEPPLDLAPF 360
|
....
gi 1046870090 239 DLQR 242
Cdd:COG0665 361 SPDR 364
|
|
| FAO_M |
pfam16350 |
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ... |
229-283 |
6.14e-16 |
|
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).
Pssm-ID: 465100 Cd Length: 56 Bit Score: 72.10 E-value: 6.14e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046870090 229 GYPSENVWELDLQRFGALQGSRTFLRHRVMEVMPLIYDLKVPRWDFQTGRQLRTS 283
Cdd:pfam16350 2 GEPPIDLWECDIRRFGPHQNNREYLRERVAENYGEVYDIHHPNEEREAGRPLRTS 56
|
|
| DAO |
pfam01266 |
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ... |
1-208 |
8.21e-16 |
|
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Pssm-ID: 426168 [Multi-domain] Cd Length: 339 Bit Score: 79.36 E-value: 8.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 1 MHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHvLTKKGRVTGVDTDkGQIECqyFVNCAGQWAYELGLSseePVS 80
Cdd:pfam01266 135 LFYPDGGHVDPARLLRALARAAEALGVRIIEGTEVTG-IEEEGGVWGVVTT-GEADA--VVNAAGAWADLLALP---GLR 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 81 IPLHACEHFYLLTRPC-DAPLQSSTPTVVDADGRIYIRN-WQGGVLSGGFEKNPKPiftegknqleiQNLREDWDHFEPL 158
Cdd:pfam01266 208 LPVRPVRGQVLVLEPLpEALLILPVPITVDPGRGVYLRPrADGRLLLGGTDEEDGF-----------DDPTPDPEEIEEL 276
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1046870090 159 LSSLLRRMPGLESVEilklvncpETF-----TADMKCIMGEsPVVQGYFVLAGMN 208
Cdd:pfam01266 277 LEAARRLFPALADIE--------RAWaglrpLPDGLPIIGR-PGSPGLYLATGHG 322
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GcvT |
COG0404 |
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and ... |
277-691 |
1.64e-87 |
|
Glycine cleavage system protein T (aminomethyltransferase) [Amino acid transport and metabolism]; Glycine cleavage system protein T (aminomethyltransferase) is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440173 [Multi-domain] Cd Length: 372 Bit Score: 279.27 E-value: 1.64e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 277 GRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVppnkdllaleqsktfykpdwfDIVESEVKCCKEAVCVIDMSSFTKFE 356
Cdd:COG0404 1 FRPLRRTPLHDRHVALGAKFVDFGGWEMPVQYP---------------------GGVIAEHLAVREAVGLFDVSHMGKIE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 357 ITstGDQALESLQYLFSNDLDV-PVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLPKDSNL 435
Cdd:COG0404 60 VT--GPDAAAFLDRLVTNDVSKlKPGRARYTLMLNEDGGIIDDLTVYRLGEDRFLLVVNAANAAKDLAWLEEHLPPDFDV 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 436 LLEDVTWKYTALNLIGPRAVDVLSELsyAPMTPDHFPTLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNE 515
Cdd:COG0404 138 TITDVTDDWALLAVQGPKAREVLAKL--TDADLSALPFMSFREGTVAGVP-VRVSRTGYTGEDGFEIYVPAEDAEALWDA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 516 VMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGiDFIGRDALLQQKQTGVYKRLVMFIL 595
Cdd:COG0404 215 LLEAGEEFGVKPCGLGARDTLRLEAGYPLYGHELDETTTPLEAGLGWAVKLDKG-DFIGKEALLRQKEEGPRRKLVGLEL 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 596 DDHDTdldlwPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEeqvvtadfinrgEYEIDIAGHRFQAK 675
Cdd:COG0404 294 DGRGV-----PRAGAPVLADGEVVGEVTSGTFSPTLGKSIALAYVPAGLARPGT------------ELEVEIRGKRVPAE 356
|
410
....*....|....*.
gi 1046870090 676 AKLYPvtsFFTHKRRK 691
Cdd:COG0404 357 VVKPP---FYDPEGER 369
|
|
| GCV_T |
pfam01571 |
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ... |
286-559 |
3.05e-82 |
|
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 460255 Cd Length: 254 Bit Score: 260.98 E-value: 3.05e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 286 YDRLDAQGARWMEKHGFERPKYFVPPNKDllaleqsktfykpdwfdiveSEVKCCKEAVCVIDMSSFTKFEITstGDQAL 365
Cdd:pfam01571 1 YDRHVALGAKFVEFAGWEMPVQYGSNGIL--------------------AEHRAVREAAGLFDVSHMGKIEVS--GPDAA 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 366 ESLQYLFSNDLD-VPVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLPKDsNLLLEDVTWKY 444
Cdd:pfam01571 59 AFLQRLTTNDVSkLKPGRATYTLMLNERGGVIDDLTVYRLGDDHFLLVVNAANREKDLAWLRKHAEKL-DVVVVDVTDDY 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 445 TALNLIGPRAVDVLSELSYAPMTPDhFPTLFCKEMSVGYANgIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYG 524
Cdd:pfam01571 138 ALLALQGPKAREVLEKLTDGDLLEA-LPFFSFREIEIGGVP-VRVSRTGYTGEDGFEIYVPAEDAVELWEALLEAGAELG 215
|
250 260 270
....*....|....*....|....*....|....*
gi 1046870090 525 IRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECG 559
Cdd:pfam01571 216 LRPAGLGARDSLRLEAGLPLYGHDLDEETTPLEAG 250
|
|
| gcvT |
PRK00389 |
glycine cleavage system aminomethyltransferase GcvT; |
280-640 |
3.68e-38 |
|
glycine cleavage system aminomethyltransferase GcvT;
Pssm-ID: 234742 [Multi-domain] Cd Length: 359 Bit Score: 145.26 E-value: 3.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 280 LRTSPLYDRLDAQGARWMEKHGFERP-KYfvppnkdllaleQSktfykpdwfdIVEsEVKCCKEAVCVIDMSSFTKFEIT 358
Cdd:PRK00389 2 LKRTPLYDLHVALGAKMVDFGGWEMPvQY------------GS----------IIE-EHHAVRTDAGLFDVSHMGEVDVT 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 359 stGDQALESLQYLFSNDLD-VPVGHIVHTGMLNEYGGHENDCSIARLTKRSFFMI--SPTDQQVhcWAWLHKYLpKDSNL 435
Cdd:PRK00389 59 --GPDALAFLQYLLANDVSkLKPGKAQYTCMLNEDGGVIDDLIVYKLSEDEYLLVvnAANREKD--LAWIKSHA-AGFGV 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 436 LLEDVTWKYTALNLIGPRAVDVLSELSYAPMtpDHFPTLFCKEMSVGYANGIRVmSMT-HTGEPGFMLYIPIEYALHVYN 514
Cdd:PRK00389 134 EVTDRSDDLAMIAVQGPKAREKLQKLTDADL--SELKPFFGAQGAEVGGGDVLV-ARTgYTGEDGFEIYLPAEDAEALWD 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 515 EVMSVGqkygIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIGRDALLQQKQTGVYKRLVMF- 593
Cdd:PRK00389 211 ALLEAG----VKPCGLGARDTLRLEAGMPLYGQDMDETITPLEAGLGWTVKLEEKRDFIGREALEAQKEAGVERKLVGLe 286
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1046870090 594 -----IlddhdtdldlwPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYV 640
Cdd:PRK00389 287 leergI-----------PRHGYPVLADGEEIGEVTSGTFSPTLGKSIALAYV 327
|
|
| DadA |
COG0665 |
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]; |
1-242 |
6.46e-21 |
|
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
Pssm-ID: 440429 [Multi-domain] Cd Length: 364 Bit Score: 94.97 E-value: 6.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 1 MHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLTKKGRVTGVDTDKGQIECQYFVNCAGQWAYELGlsSEEPVS 80
Cdd:COG0665 140 LYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLL--PMLGLR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 81 IPLHACEHFYLLTRPCDAPLqssTPTVVDaDGRIYIRNWQGG--VLSGGFEKNPkpiftegknqleiQNLREDWDHFEPL 158
Cdd:COG0665 218 LPLRPVRGYVLVTEPLPDLP---LRPVLD-DTGVYLRPTADGrlLVGGTAEPAG-------------FDRAPTPERLEAL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 159 LSSLLRRMPGLESVEILKLVNCPETFTADMKCIMGESPVVQGYFVLAGMNsaglslgggagkllAEWMVYGYPSENVWEL 238
Cdd:COG0665 281 LRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGghgvtlapaagrllADLILGGEPPLDLAPF 360
|
....
gi 1046870090 239 DLQR 242
Cdd:COG0665 361 SPDR 364
|
|
| FAO_M |
pfam16350 |
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent ... |
229-283 |
6.14e-16 |
|
FAD dependent oxidoreductase central domain; This domain occurs in several FAD dependent oxidoreductases: Sarcosine dehydrogenase, Dimethylglycine dehydrogenase and Dimethylglycine dehydrogenase. It is situated between the DAO domain (pfam01266) and the GCV_T domain (pfam01571).
Pssm-ID: 465100 Cd Length: 56 Bit Score: 72.10 E-value: 6.14e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1046870090 229 GYPSENVWELDLQRFGALQGSRTFLRHRVMEVMPLIYDLKVPRWDFQTGRQLRTS 283
Cdd:pfam16350 2 GEPPIDLWECDIRRFGPHQNNREYLRERVAENYGEVYDIHHPNEEREAGRPLRTS 56
|
|
| DAO |
pfam01266 |
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ... |
1-208 |
8.21e-16 |
|
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Pssm-ID: 426168 [Multi-domain] Cd Length: 339 Bit Score: 79.36 E-value: 8.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 1 MHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHvLTKKGRVTGVDTDkGQIECqyFVNCAGQWAYELGLSseePVS 80
Cdd:pfam01266 135 LFYPDGGHVDPARLLRALARAAEALGVRIIEGTEVTG-IEEEGGVWGVVTT-GEADA--VVNAAGAWADLLALP---GLR 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 81 IPLHACEHFYLLTRPC-DAPLQSSTPTVVDADGRIYIRN-WQGGVLSGGFEKNPKPiftegknqleiQNLREDWDHFEPL 158
Cdd:pfam01266 208 LPVRPVRGQVLVLEPLpEALLILPVPITVDPGRGVYLRPrADGRLLLGGTDEEDGF-----------DDPTPDPEEIEEL 276
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1046870090 159 LSSLLRRMPGLESVEilklvncpETF-----TADMKCIMGEsPVVQGYFVLAGMN 208
Cdd:pfam01266 277 LEAARRLFPALADIE--------RAWaglrpLPDGLPIIGR-PGSPGLYLATGHG 322
|
|
| PLN02319 |
PLN02319 |
aminomethyltransferase |
386-640 |
4.62e-14 |
|
aminomethyltransferase
Pssm-ID: 177953 [Multi-domain] Cd Length: 404 Bit Score: 74.76 E-value: 4.62e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 386 TGML----NEYGGHENDCSIARLTKRSFFMI-----SPTDQQvHCWAWLHKYLPKDsnlllEDVTW----KYTALNLIGP 452
Cdd:PLN02319 112 TGTLsvftNEKGGIIDDTVITKVTDDHIYLVvnagcRDKDLA-HIEEHMKAFKAKG-----GDVSWhvhdERSLLALQGP 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 453 RAVDVLSELSYAPMTPDHFPTLfcKEMSVgyaNGI--RVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKyGIRNAGY 530
Cdd:PLN02319 186 LAAPVLQHLTKEDLSKMYFGDF--RITDI---NGAdcFLTRTGYTGEDGFEISVPSEHAVDLAKALLEKSEG-KVRLTGL 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 531 YALRSLRIEKFFAFWGQDLNTLTTPLECG-----GESRvkLEKGiDFIGRDALLQQKQTGVYKRLVMFILDdhdtdldlw 605
Cdd:PLN02319 260 GARDSLRLEAGLCLYGNDLEEHITPVEAGlawtiGKRR--RAEG-GFLGADVILKQLKEGVSRRRVGFISS--------- 327
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1046870090 606 pwwGEP------IY-RNGKYAGKTTSSAYSYTLERHVCLGYV 640
Cdd:PLN02319 328 ---GAParshseILdESGEKIGEVTSGGFSPCLKKNIAMGYV 366
|
|
| dmdA |
PRK12486 |
dimethylsulfoniopropionate demethylase; |
278-662 |
2.07e-13 |
|
dimethylsulfoniopropionate demethylase;
Pssm-ID: 237113 [Multi-domain] Cd Length: 368 Bit Score: 72.48 E-value: 2.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 278 RQLRTSPLYDRLDAQGArwmekhgferpKYFVPPNKDLLaleqsktfykPDWFDIVESEVKCCKEAVCVIDMSSFTKFEI 357
Cdd:PRK12486 9 RRLRRTPFSDGVEAAGV-----------KAYTVYNHMLL----------PTVFESVEDDYAHLKEHVQVWDVAVERQVEI 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 358 TstGDQALESLQYLFSNDLD-VPVGHIVHTGMLNEYGGHENDCSIARLTKRSFFmISPTDQQVHCWAwlhKYLPKDSNLL 436
Cdd:PRK12486 68 R--GPDAARLVQMLTPRDLRgMKPGQCYYVPIVDETGGMLNDPVALKLAEDRWW-ISIADSDLLLWV---KGLANGRKLD 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 437 LEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFptlfckeMSVGYAN--GIRvMSMTHTG---EPGFMLYIP-IEYAL 510
Cdd:PRK12486 142 VLVVEPDVSPLAVQGPKADALMARVFGEAIRDLRF-------FRFGYFDfeGTD-LVIARSGyskQGGFEIYVEgSDLGM 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 511 HVYNEVMSVGQKYGIRnAGYYALRSlRIEKFFAFWGQDLNTLTTPLECGGESRVKLEKGIDFIGRDALLQQKQTGVYKRL 590
Cdd:PRK12486 214 PLWDALFEAGKDLNVR-AGCPNLIE-RIEGGLLSYGNDMTRDNTPHECGLGRFCNTQTDIGCIGKDALLRVAKEGPQKQI 291
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1046870090 591 VMFILDDHDTDLDLWPWwgePIYRNGKYAGKTTSSAYSYTLERHVCLGYVHNFSEDSGEE-QVVTADFINRGE 662
Cdd:PRK12486 292 RGIKIGGERIPPCDRAW---PLLAGDNRVGQVTSAAYSPDFQTNVAIGMVRMTHWDPGTGlEVETPDGMRPAT 361
|
|
| GCV_T_C |
pfam08669 |
Glycine cleavage T-protein C-terminal barrel domain; This is a family of glycine cleavage ... |
588-675 |
7.18e-12 |
|
Glycine cleavage T-protein C-terminal barrel domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 462554 [Multi-domain] Cd Length: 80 Bit Score: 61.34 E-value: 7.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 588 KRLVMFILDDHDTdldlWPWWGEPIYRNGKYAGKTTSSAYSYTLERHVCLGYVHnfsedsgeeqvvtADFINRG-EYEID 666
Cdd:pfam08669 1 RRLVGLELDDGDP----LLRGGEPVLRDGEVVGYVTSGAYSPTLGKSIALAYVD-------------AELAKPGtEVEVE 63
|
....*....
gi 1046870090 667 IAGHRFQAK 675
Cdd:pfam08669 64 IRGKRVPAT 72
|
|
| gcvT |
PRK13579 |
glycine cleavage system aminomethyltransferase GcvT; |
357-640 |
4.53e-09 |
|
glycine cleavage system aminomethyltransferase GcvT;
Pssm-ID: 237435 [Multi-domain] Cd Length: 370 Bit Score: 58.81 E-value: 4.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 357 ITSTGDQALESLQYLFSND-LDVPVGHIVHTGMLNEYGGHENDCSIARLTKRsFFMISPTDQQVHCWAWLHKYLPKDSNL 435
Cdd:PRK13579 63 IEVSGKDAAAALERLVPVDiLALKEGRQRYTFFTNEQGGILDDLMVTNLGDH-LFLVVNAACKDADIAHLREHLSDECEV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 436 -LLEDvtwkYTALNLIGPRAVDVLSELSyapmtPDHFPTLFckeMSVGyanGIRVMSMT-------HTGEPGFMLYIPIE 507
Cdd:PRK13579 142 nPLDD----RALLALQGPEAEAVLADLG-----PPVAALRF---MDGF---EPRLHGVDcfvsrsgYTGEDGFEISVPAD 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046870090 508 YA------LHVYNEVMSVGqkYGIRNagyyalrSLRIEKFFAFWGQDLNTLTTPLECGGE---SRVKLEKGiDFIGRDAL 578
Cdd:PRK13579 207 AAealaeaLLADPRVEPIG--LGARD-------SLRLEAGLCLYGHDIDTTTTPVEAALEwaiQKARREAG-GFPGAKAI 276
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1046870090 579 LQQKQTGVYKRLVMFILDDHDTDLDlwpwwGEPIYRN-GKYAGKTTSSAYSYTLERHVCLGYV 640
Cdd:PRK13579 277 LAALAKGASRRRVGLKPEGRAPVRE-----GAPLFDDaGTEIGTVTSGGFGPSVGGPVAMGYV 334
|
|
| LhgO |
COG0579 |
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism]; |
1-68 |
7.34e-04 |
|
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
Pssm-ID: 440344 [Multi-domain] Cd Length: 418 Bit Score: 42.44 E-value: 7.34e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1046870090 1 MHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLTKKGRVTgVDTDKGQIECQYFVNCAGQWA 68
Cdd:COG0579 142 LYSPSTGIVDPGALTRALAENAEANGVELLLNTEVTGIEREGDGWE-VTTNGGTIRARFVINAAGLYA 208
|
|
| |
