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Conserved domains on  [gi|1046868189|ref|XP_017456436|]
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zinc finger protein 532 isoform X4 [Rattus norvegicus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 13676732)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-C2H2_11 pfam16622
zinc-finger C2H2-type; Zinc-finger of C2H2 type found in higher eukaryotes.
 1199-1225 1.11e-10

zinc-finger C2H2-type; Zinc-finger of C2H2 type found in higher eukaryotes.


:

Pssm-ID: 465205  Cd Length: 27  Bit Score: 57.44  E-value: 1.11e-10
                           10        20
                   ....*....|....*....|....*..
gi 1046868189 1199 SSYQCRECGLCYTSHVSLSRHLFIVHK 1225
Cdd:pfam16622    1 STCQCLLCGLCFTSQGSLSRHLFIVHK 27
zf-RING_7 pfam02591
C4-type zinc ribbon domain; Zn-ribbon_9 is a Zn-ribbon domain rich in aromatic and positively ...
 781-816 3.68e-03

C4-type zinc ribbon domain; Zn-ribbon_9 is a Zn-ribbon domain rich in aromatic and positively charged amino acid residues. This C-terminal Zn-ribbon domain consists of two beta-strands acting as a scaffold for the two Zn knuckles. Both pairs of cysteines making up the two Zn knuckles are situated at highly conserved sharp beta-turns, an arrangement that facilitates the tetrahedral coordination of the divalent Zn ion. The two Zn-knuckle cysteine motifs are separated by 20 residues, 9 of which form an alpha-helix (helix 4).Structural modelling suggests this domain may bind nucleic acids. The domain appears to bind flaA-mRNA, thus contributing to flagellum formation and motility.


:

Pssm-ID: 426857 [Multi-domain]  Cd Length: 33  Bit Score: 36.34  E-value: 3.68e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1046868189  781 TCTVCQMLLPNQcsyaSHQRIHQHKSPYTCPECGAI 816
Cdd:pfam02591    1 RCGGCRMELPPQ----LLNEIRAAAEIVRCPECGRI 32
zf-C2H2_6 pfam13912
C2H2-type zinc finger;
1263-1284 5.79e-03

C2H2-type zinc finger;


:

Pssm-ID: 433576  Cd Length: 27  Bit Score: 35.68  E-value: 5.79e-03
                           10        20
                   ....*....|....*....|..
gi 1046868189 1263 KCKVCAKTFETEAALNTHMRTH 1284
Cdd:pfam13912    3 ECSECGKSFPSYQALGGHKKSH 24
 
Name Accession Description Interval E-value
zf-C2H2_11 pfam16622
zinc-finger C2H2-type; Zinc-finger of C2H2 type found in higher eukaryotes.
 1199-1225 1.11e-10

zinc-finger C2H2-type; Zinc-finger of C2H2 type found in higher eukaryotes.


Pssm-ID: 465205  Cd Length: 27  Bit Score: 57.44  E-value: 1.11e-10
                           10        20
                   ....*....|....*....|....*..
gi 1046868189 1199 SSYQCRECGLCYTSHVSLSRHLFIVHK 1225
Cdd:pfam16622    1 STCQCLLCGLCFTSQGSLSRHLFIVHK 27
zf-RING_7 pfam02591
C4-type zinc ribbon domain; Zn-ribbon_9 is a Zn-ribbon domain rich in aromatic and positively ...
 781-816 3.68e-03

C4-type zinc ribbon domain; Zn-ribbon_9 is a Zn-ribbon domain rich in aromatic and positively charged amino acid residues. This C-terminal Zn-ribbon domain consists of two beta-strands acting as a scaffold for the two Zn knuckles. Both pairs of cysteines making up the two Zn knuckles are situated at highly conserved sharp beta-turns, an arrangement that facilitates the tetrahedral coordination of the divalent Zn ion. The two Zn-knuckle cysteine motifs are separated by 20 residues, 9 of which form an alpha-helix (helix 4).Structural modelling suggests this domain may bind nucleic acids. The domain appears to bind flaA-mRNA, thus contributing to flagellum formation and motility.


Pssm-ID: 426857 [Multi-domain]  Cd Length: 33  Bit Score: 36.34  E-value: 3.68e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1046868189  781 TCTVCQMLLPNQcsyaSHQRIHQHKSPYTCPECGAI 816
Cdd:pfam02591    1 RCGGCRMELPPQ----LLNEIRAAAEIVRCPECGRI 32
zf-C2H2_6 pfam13912
C2H2-type zinc finger;
1263-1284 5.79e-03

C2H2-type zinc finger;


Pssm-ID: 433576  Cd Length: 27  Bit Score: 35.68  E-value: 5.79e-03
                           10        20
                   ....*....|....*....|..
gi 1046868189 1263 KCKVCAKTFETEAALNTHMRTH 1284
Cdd:pfam13912    3 ECSECGKSFPSYQALGGHKKSH 24
 
Name Accession Description Interval E-value
zf-C2H2_11 pfam16622
zinc-finger C2H2-type; Zinc-finger of C2H2 type found in higher eukaryotes.
 1199-1225 1.11e-10

zinc-finger C2H2-type; Zinc-finger of C2H2 type found in higher eukaryotes.


Pssm-ID: 465205  Cd Length: 27  Bit Score: 57.44  E-value: 1.11e-10
                           10        20
                   ....*....|....*....|....*..
gi 1046868189 1199 SSYQCRECGLCYTSHVSLSRHLFIVHK 1225
Cdd:pfam16622    1 STCQCLLCGLCFTSQGSLSRHLFIVHK 27
zf-RING_7 pfam02591
C4-type zinc ribbon domain; Zn-ribbon_9 is a Zn-ribbon domain rich in aromatic and positively ...
 781-816 3.68e-03

C4-type zinc ribbon domain; Zn-ribbon_9 is a Zn-ribbon domain rich in aromatic and positively charged amino acid residues. This C-terminal Zn-ribbon domain consists of two beta-strands acting as a scaffold for the two Zn knuckles. Both pairs of cysteines making up the two Zn knuckles are situated at highly conserved sharp beta-turns, an arrangement that facilitates the tetrahedral coordination of the divalent Zn ion. The two Zn-knuckle cysteine motifs are separated by 20 residues, 9 of which form an alpha-helix (helix 4).Structural modelling suggests this domain may bind nucleic acids. The domain appears to bind flaA-mRNA, thus contributing to flagellum formation and motility.


Pssm-ID: 426857 [Multi-domain]  Cd Length: 33  Bit Score: 36.34  E-value: 3.68e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1046868189  781 TCTVCQMLLPNQcsyaSHQRIHQHKSPYTCPECGAI 816
Cdd:pfam02591    1 RCGGCRMELPPQ----LLNEIRAAAEIVRCPECGRI 32
zf-C2H2_6 pfam13912
C2H2-type zinc finger;
1263-1284 5.79e-03

C2H2-type zinc finger;


Pssm-ID: 433576  Cd Length: 27  Bit Score: 35.68  E-value: 5.79e-03
                           10        20
                   ....*....|....*....|..
gi 1046868189 1263 KCKVCAKTFETEAALNTHMRTH 1284
Cdd:pfam13912    3 ECSECGKSFPSYQALGGHKKSH 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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