|
Name |
Accession |
Description |
Interval |
E-value |
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
150-907 |
0e+00 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 1189.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQ 229
Cdd:pfam10174 1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 230 DELRTQRDLNHLLQQE---SGNRGAEHF-TIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:pfam10174 81 DELRAQRDLNQLLQQDfttSPVDGEDKFsTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 306 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT 385
Cdd:pfam10174 161 KKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Cdd:pfam10174 241 KISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 466 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQ 545
Cdd:pfam10174 321 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 546 KKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDL 625
Cdd:pfam10174 401 KKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKDL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 626 KEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRL 705
Cdd:pfam10174 481 KEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 706 KQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE----RHMKDQNKKVANLKHNQQLEKKKNAQLLEE 781
Cdd:pfam10174 561 RLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELEsltlRQMKEQNKKVANIKHGQQEMKKKGAQLLEE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 782 VRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISE 861
Cdd:pfam10174 641 ARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERRKQLEEILEMKQEALLAAISE 720
|
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 1958683006 862 KDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 907
Cdd:pfam10174 721 KDANIALLELSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 766
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
363-907 |
6.58e-19 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 92.39 E-value: 6.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 363 RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQE 442
Cdd:TIGR04523 46 KNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVE 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 443 LSKKE--------------SELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR---LRLEEKESF 505
Cdd:TIGR04523 126 LNKLEkqkkenkknidkflTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKnklLKLELLLSN 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 506 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALAT 585
Cdd:TIGR04523 206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 586 LEEALSEKERIIERLKEQRERD-DRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRD--- 661
Cdd:TIGR04523 286 LEKQLNQLKSEISDLNNQKEQDwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQrel 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 662 ----SKLKSLEIAIEQKKEECNKLEAQLKKAH-NIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEV 736
Cdd:TIGR04523 366 eekqNEIEKLKKENQSYKQEIKNLESQINDLEsKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 737 ENEKNDKDKKIAELERHMKDQNKKVANLKhnqqLEKKKNAQLLEEVRRREDSmvDNSQHLQIEELMNALEKTRQELDATK 816
Cdd:TIGR04523 446 TNQDSVKELIIKNLDNTRESLETQLKVLS----RSINKIKQNLEQKQKELKS--KEKELKKLNEEKKELEEKVKDLTKKI 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 817 ARLASTQQSLAEKEAHLANLRMERRKQLEEI-LEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVH 895
Cdd:TIGR04523 520 SSLKEKIEKLESEKKEKESKISDLEDELNKDdFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKK 599
|
570
....*....|..
gi 1958683006 896 QLKQQTQNRMKL 907
Cdd:TIGR04523 600 DLIKEIEEKEKK 611
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
295-893 |
3.02e-18 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 90.51 E-value: 3.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 295 KQTLNARDESIKKLLemlqskglpsKSLEDDNERTRRMAEAESQVSHlevILDQKEKENIHLREELhrrSQLQPEPAKTK 374
Cdd:PRK03918 171 IKEIKRRIERLEKFI----------KRTENIEELIKEKEKELEEVLR---EINEISSELPELREEL---EKLEKEVKELE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 375 ALQTVIEMKDTKIASLERNIRDLEDEIQmlkangvlNTEDREEEIKqievykSHSKFMKTKIDQLKqELSKKESELLalq 454
Cdd:PRK03918 235 ELKEEIEELEKELESLEGSKRKLEEKIR--------ELEERIEELK------KEIEELEEKVKELK-ELKEKAEEYI--- 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 455 tKLETLSNQNSDCKQHIEVLKESLtakEQRAAILQTEVDalrlRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDML 534
Cdd:PRK03918 297 -KLSEFYEEYLDELREIEKRLSRL---EEEINGIEERIK----ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 535 EVKERKINVLQKKIENLQEQLrdkDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKE--------QRER 606
Cdd:PRK03918 369 AKKEELERLKKRLTGLTPEKL---EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcGREL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 607 DDRERLEEIESFRKENKDLKEKVnalqAELTEKESsliDLKEHASSLASAgLKRDSKLKSLEIAIEQKKEecnkLEAQLK 686
Cdd:PRK03918 446 TEEHRKELLEEYTAELKRIEKEL----KEIEEKER---KLRKELRELEKV-LKKESELIKLKELAEQLKE----LEEKLK 513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 687 KaHNIEDDSRMNPEFADRLKQLDKeasyyrdeCGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKH 766
Cdd:PRK03918 514 K-YNLEELEKKAEEYEKLKEKLIK--------LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 767 NQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEElmNALEKTRQELDATKARLASTQQSLAEKEAHLANLRM----ERRK 842
Cdd:PRK03918 585 ESVEELEERLKELEPFYNEYLELKDAEKELEREE--KELKKLEEELDKAFEELAETEKRLEELRKELEELEKkyseEEYE 662
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 843 QLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRL 893
Cdd:PRK03918 663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
191-889 |
4.15e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 90.13 E-value: 4.15e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 191 KKERVLRKEEAARMSV---------LKEQM-RVSHEENQHLQLtiQALQDELRTQRDLNHLLQQESgnrgaehftielTE 260
Cdd:TIGR02169 171 KKEKALEELEEVEENIerldliideKRQQLeRLRREREKAERY--QALLKEKREYEGYELLKEKEA------------LE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 261 ENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglpskslEDDNERTRRMAEAESQVS 340
Cdd:TIGR02169 237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE------------EEQLRVKEKIGELEAEIA 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 341 HLEVILDQKEKEnihLREELHRRSQLQPEPAKTKAlqtVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIK 420
Cdd:TIGR02169 305 SLERSIAEKERE---LEDAEERLAKLEAEIDKLLA---EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDK 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 421 QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAkeqraaiLQTEVDALRLRLE 500
Cdd:TIGR02169 379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE-------LEEEKEDKALEIK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 501 EKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD------------- 567
Cdd:TIGR02169 452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAsiqgvhgtvaqlg 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 568 --------------------------------------------------RVKSLQTDSS-------------------- 577
Cdd:TIGR02169 532 svgeryataievaagnrlnnvvveddavakeaiellkrrkagratflplnKMRDERRDLSilsedgvigfavdlvefdpk 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 578 ----------------NTDTA--------LATLEEALSEKERII---ERLKEQRERDDRERLEEIESFRKENKDLKEKVN 630
Cdd:TIGR02169 612 yepafkyvfgdtlvveDIEAArrlmgkyrMVTLEGELFEKSGAMtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELS 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 631 ALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKK-AHNIEDDSRMNPEFADRLKQLD 709
Cdd:TIGR02169 692 SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSlEQEIENVKSELKELEARIEELE 771
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 710 KEASYYRDECGKAQAEVDRllEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSM 789
Cdd:TIGR02169 772 EDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI 849
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 790 VDNSQhlQIEELMNALEKTRQELDATKARLAstqqSLAEKEAHLANLRMERRKQLEEiLEMKQEALLAAISEKDANIALL 869
Cdd:TIGR02169 850 KSIEK--EIENLNGKKEELEEELEELEAALR----DLESRLGDLKKERDELEAQLRE-LERKIEELEAQIEKKRKRLSEL 922
|
810 820
....*....|....*....|
gi 1958683006 870 ELSASKKKKTQEEVMALKRE 889
Cdd:TIGR02169 923 KAKLEALEEELSEIEDPKGE 942
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
395-911 |
9.44e-18 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.84 E-value: 9.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 395 RDLEDEIQMLKANGVLNTEDREEEikQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVL 474
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEA--ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 475 KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 555 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQA 634
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 635 ELTEKESSLIDLKEHASSLASAGLKRDSKL------KSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQL 708
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLeelaeaAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 709 DKEASYYRDECGKA-QAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVR---- 783
Cdd:COG1196 534 AAYEAALEAALAAAlQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLReada 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 784 ---RREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAIS 860
Cdd:COG1196 614 ryyVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 861 EKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADN 911
Cdd:COG1196 694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
146-907 |
2.98e-17 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 87.48 E-value: 2.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 146 TMLDLQAQLKELQRENDLL----RKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARMSVLKEQMRvsheenqHL 221
Cdd:pfam15921 111 SVIDLQTKLQEMQMERDAMadirRRESQSQEDLRNQLQNTVH-----ELEAAKCLKEDMLEDSNTQIEQLR-------KM 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 222 QLTIQALQDELRTqrdLNHLLQQESGNRGAEHFTieLTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNAr 301
Cdd:pfam15921 179 MLSHEGVLQEIRS---ILVDFEEASGKKIYEHDS--MSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKS- 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 302 dESIKKLLEMLQSKGLPSKSLEDDNE-----RTRRMAEAESQV----SHLEVILDQKEKENI----HLREELHRRSQLQP 368
Cdd:pfam15921 253 -ESQNKIELLLQQHQDRIEQLISEHEveitgLTEKASSARSQAnsiqSQLEIIQEQARNQNSmymrQLSDLESTVSQLRS 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 369 EPAKTKAL----------QTVIEMKDTKIASLERN-----IRDLEDEIQMLKAngvlnteDREEEIKQIEVYKSHSKFM- 432
Cdd:pfam15921 332 ELREAKRMyedkieelekQLVLANSELTEARTERDqfsqeSGNLDDQLQKLLA-------DLHKREKELSLEKEQNKRLw 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 433 ------KTKIDQLKQELSKKESELLALQTKLETLsnqNSDCKQHIEVLKESLTAKEQRAAilqtEVDALRLRLEEKESFL 506
Cdd:pfam15921 405 drdtgnSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQMERQMAAIQGKNESLE----KVSSLTAQLESTKEML 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 507 NKktkQLQDLTEEKGTLAGEIRDMKDM---LEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssNTDTAL 583
Cdd:pfam15921 478 RK---VVEELTAKKMTLESSERTVSDLtasLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR----NVQTEC 550
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 584 ATLEEALSEKERIIERLKEQrerddrerleeIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSK 663
Cdd:pfam15921 551 EALKLQMAEKDKVIEILRQQ-----------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAK 619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 664 LKSLEIAIEqkkeecnklEAQLKKAHNIEDDSrmnpefaDRLKQLdkeasyyRDecgkAQAEVDRLLEILKEVENEKNDK 743
Cdd:pfam15921 620 IRELEARVS---------DLELEKVKLVNAGS-------ERLRAV-------KD----IKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 744 DKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHlqieeLMNALEKTRQELDATKARLASTQ 823
Cdd:pfam15921 673 SEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGH-----AMKVAMGMQKQITAKRGQIDALQ 747
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 824 QSLAEKEAHLANLRMERRKQLEEILEMKQEaLLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRL---------V 894
Cdd:pfam15921 748 SKIQFLEEAMTNANKEKHFLKEEKNKLSQE-LSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKAslqfaecqdI 826
|
810
....*....|...
gi 1958683006 895 HQLKQQTQNRMKL 907
Cdd:pfam15921 827 IQRQEQESVRLKL 839
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
189-871 |
8.11e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 86.26 E-value: 8.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 189 ELKKErvlrkEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQEsgnrgaehftIELTEENFRRLQA 268
Cdd:TIGR02168 217 ELKAE-----LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK----------LEELRLEVSELEE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 269 EHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGlpsKSLEDDNERTRRMAEAESQVSHLEVILDQ 348
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE---SKLDELAEELAELEEKLEELKEELESLEA 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 349 KEKENIHLREELHRRSQlqpepaktkALQTVIEMKDTKIASLERNIRDLEDEIQMLKANgvLNTEDREEEIKQIEVYKSH 428
Cdd:TIGR02168 359 ELEELEAELEELESRLE---------ELEEQLETLRSKVAQLELQIASLNNEIERLEAR--LERLEDRRERLQQEIEELL 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 429 SKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFlnk 508
Cdd:TIGR02168 428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGF--- 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 509 kTKQLQDLTEEKGTLAGEIRDMKDMLEVKER-------------------------------------KINVL------- 544
Cdd:TIGR02168 505 -SEGVKALLKNQSGLSGILGVLSELISVDEGyeaaieaalggrlqavvvenlnaakkaiaflkqnelgRVTFLpldsikg 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 545 QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALA------TLEEALS------EKERII--------------- 597
Cdd:TIGR02168 584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGgvlvvdDLDNALElakklrPGYRIVtldgdlvrpggvitg 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 598 -------ERLKEQRERDD-RERLEEIESfrkENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669
Cdd:TIGR02168 664 gsaktnsSILERRREIEElEEKIEELEE---KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 670 AIEQKKEECNKLEAQLKKAHNIEDdsrmnpEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAE 749
Cdd:TIGR02168 741 EVEQLEERIAQLSKELTELEAEIE------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 750 LERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSqhLQIEELMNALEKTRQELDATKARLASTQQSLAEK 829
Cdd:TIGR02168 815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA--AEIEELEELIEELESELEALLNERASLEEALALL 892
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 1958683006 830 EAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLEL 871
Cdd:TIGR02168 893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
140-893 |
2.06e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 84.72 E-value: 2.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 140 RQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIK--TFWSPELKKERVLRKEEAARMSV----------- 206
Cdd:TIGR02168 276 VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEelEAQLEELESKLDELAEELAELEEkleelkeeles 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 207 LKEQMRVSHEENQHLQLTIQALQDELRTQR-DLNHLLQQESGNRGaehfTIELTEENFRRLQAEHDRQAKELFLLRKTLE 285
Cdd:TIGR02168 356 LEAELEELEAELEELESRLEELEEQLETLRsKVAQLELQIASLNN----EIERLEARLERLEDRRERLQQEIEELLKKLE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 286 EMELriETQKQTLNARDESIKKLLEMLQS--------KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLR 357
Cdd:TIGR02168 432 EAEL--KELQAELEELEEELEELQEELERleealeelREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 358 EELHRRSQLqpePAKTKALQTVIEMKDTKIASLERnirDLEDEIQMLKangvlnTEDREEEIKQIEVYKSHSKFMKTKID 437
Cdd:TIGR02168 510 ALLKNQSGL---SGILGVLSELISVDEGYEAAIEA---ALGGRLQAVV------VENLNAAKKAIAFLKQNELGRVTFLP 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 438 QLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKkTKQlQDLT 517
Cdd:TIGR02168 578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIV-TLD-GDLV 655
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 518 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 597
Cdd:TIGR02168 656 RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 598 ERLKEQRERddreRLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasslasaglkrdsKLKSLEIAIEQKKEE 677
Cdd:TIGR02168 736 ARLEAEVEQ----LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA--------------EIEELEAQIEQLKEE 797
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 678 CNKLEAQLKKAHNieddsrmnpefadRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQ 757
Cdd:TIGR02168 798 LKALREALDELRA-------------ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 758 NKKVAnlKHNQQLEKKKNAQLLEEVRRREdsmvdnsQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLR 837
Cdd:TIGR02168 865 EELIE--ELESELEALLNERASLEEALAL-------LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE 935
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 838 MERRKQLEEILEmKQEALLAAISEKDANIALLELSAskkkktQEEVMALKREKDRL 893
Cdd:TIGR02168 936 VRIDNLQERLSE-EYSLTLEEAEALENKIEDDEEEA------RRRLKRLENKIKEL 984
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
381-899 |
2.53e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 2.53e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 381 EMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVykshskfMKTKIDQLKQELSKKESELLALQTKLETL 460
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAE-------LEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 461 SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERK 540
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 541 INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE---RDDRERLEEIES 617
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEeeeEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 618 FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS-------------------------AGLKRDSKLKSLEIAIE 672
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAArllllleaeadyegflegvkaalllAGLRGLAGAVAVLIGVE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 673 QKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQ----------LDKEASYYRDECGKAQAEVDRLLEILKEVENEKND 742
Cdd:COG1196 534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 743 KDKKIAEL-------ERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDAT 815
Cdd:COG1196 614 RYYVLGDTllgrtlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 816 KARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMA-LKREKDRLV 894
Cdd:COG1196 694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEeLERELERLE 773
|
....*
gi 1958683006 895 HQLKQ 899
Cdd:COG1196 774 REIEA 778
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
386-849 |
3.34e-16 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 83.94 E-value: 3.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHskfmKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVR 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 466 DCKQHIEVLKESLT--------------AKEQRAAILQTEVDALRLRLEEKESFLNKKTKQL--------------QDLT 517
Cdd:PRK02224 283 DLRERLEELEEERDdllaeaglddadaeAVEARREELEDRDEELRDRLEECRVAAQAHNEEAeslredaddleeraEELR 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 518 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 597
Cdd:PRK02224 363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERV 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 598 ERLKEQRE--------------------RDDRERLEEIESfrkENKDLKEKVNALQA------ELTEKESSLIDLKEHAS 651
Cdd:PRK02224 443 EEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEA---ELEDLEEEVEEVEErleraeDLVEAEDRIERLEERRE 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 652 SLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPE-FADRLKQLDKEasyyRDECGKAQAEVDRLL 730
Cdd:PRK02224 520 DLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEeAREEVAELNSK----LAELKERIESLERIR 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 731 EILKEVEN------EKNDKDKKIAELERHMKDQNKKVANLKhnQQLEKKKNAQLLEEVRRREDSMVDnsqhlQIEELMNA 804
Cdd:PRK02224 596 TLLAAIADaedeieRLREKREALAELNDERRERLAEKRERK--RELEAEFDEARIEEAREDKERAEE-----YLEQVEEK 668
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1958683006 805 LEKTRQELDATKARLASTQQSLAEkeahLANLRmERRKQLEEILE 849
Cdd:PRK02224 669 LDELREERDDLQAEIGAVENELEE----LEELR-ERREALENRVE 708
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
250-908 |
4.27e-16 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 83.63 E-value: 4.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 250 GAEHFTIELTEENF------RRLQAEHDRQAKELFLLRKT-------LEEMEL---------RIETQKQTlNARDESIKK 307
Cdd:pfam15921 72 GKEHIERVLEEYSHqvkdlqRRLNESNELHEKQKFYLRQSvidlqtkLQEMQMerdamadirRRESQSQE-DLRNQLQNT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 308 LLEMLQSKGLPSKSLEDDN---ERTRRMAEAESQVSH--LEVILDQKEKENIHLREelHRRSQLQPEPAKTKALQTVIEM 382
Cdd:pfam15921 151 VHELEAAKCLKEDMLEDSNtqiEQLRKMMLSHEGVLQeiRSILVDFEEASGKKIYE--HDSMSTMHFRSLGSAISKILRE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 383 KDTKIASLERNIRDLEDEIQMLKAngvlntedreEEIKQIEVykshskFMKTKIDQLKQELSKKESELLALQTKLETLSN 462
Cdd:pfam15921 229 LDTEISYLKGRIFPVEDQLEALKS----------ESQNKIEL------LLQQHQDRIEQLISEHEVEITGLTEKASSARS 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 463 QNSDCKQHIEVLKESltAKEQRAAILqtevdalrlrleekesflnkktKQLQDLTEEKGTLAGEIRDMKDMLEvkerkin 542
Cdd:pfam15921 293 QANSIQSQLEIIQEQ--ARNQNSMYM----------------------RQLSDLESTVSQLRSELREAKRMYE------- 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 543 vlqKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER---DDRERLEEIESFR 619
Cdd:pfam15921 342 ---DKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRlwdRDTGNSITIDHLR 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 620 KENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK-KAHNIEDDSRMN 698
Cdd:pfam15921 419 RELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTaKKMTLESSERTV 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 699 PEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAE---LERHMKDQNKKVANLKhnQQLEKKkn 775
Cdd:pfam15921 499 SDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTEceaLKLQMAEKDKVIEILR--QQIENM-- 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 776 AQLLEEVRRREDSMVDNSQHLQIEelmnaLEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRK-------QLEEIL 848
Cdd:pfam15921 575 TQLVGQHGRTAGAMQVEKAQLEKE-----INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKlvnagseRLRAVK 649
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 849 EMKQE--ALLAAI--SEKDANiALLELSASKKKKTQEEVMALKREKDRLVHQLK------QQTQNRMKLM 908
Cdd:pfam15921 650 DIKQErdQLLNEVktSRNELN-SLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKsaqselEQTRNTLKSM 718
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
331-849 |
5.12e-15 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 80.08 E-value: 5.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 331 RMAEAESQVSHLEVILDQKEKENIHLREELhrrsqlqpepaktKALQTVI---EMKDTKIASLERNIRDLEDEIQmlkan 407
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETR-------------DEADEVLeehEERREELETLEAEIEDLRETIA----- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 408 gvlNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAA 486
Cdd:PRK02224 269 ---ETEREREELAeEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 487 ILQTEVDALRLRLEEKEsflnkktkqlqdltEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK 566
Cdd:PRK02224 346 SLREDADDLEERAEELR--------------EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 567 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE--------------------RDDRERLEEIES----FRKEN 622
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEAeledLEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 623 KDLKEKVNALQaELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPE-F 701
Cdd:PRK02224 492 EEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEeA 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 702 ADRLKQLDKEasyyRDECGKAQAEVDRLLEILKEVEN------EKNDKDKKIAELER----HMKDQNKKVANLKH----- 766
Cdd:PRK02224 571 REEVAELNSK----LAELKERIESLERIRTLLAAIADaedeieRLREKREALAELNDerreRLAEKRERKRELEAefdea 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 767 --NQQLEKKKNAQL--------LEEVRRREDS------MVDNSqhlqIEELmNALEKTRQELDATKARLASTQQSLAEKE 830
Cdd:PRK02224 647 riEEAREDKERAEEyleqveekLDELREERDDlqaeigAVENE----LEEL-EELRERREALENRVEALEALYDEAEELE 721
|
570
....*....|....*....
gi 1958683006 831 AHLANLRMERRKQLEEILE 849
Cdd:PRK02224 722 SMYGDLRAELRQRNVETLE 740
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
488-858 |
1.49e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 78.57 E-value: 1.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 488 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIrdmkdmlEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD 567
Cdd:TIGR02169 686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 568 RvkslqtdssntdtaLATLEEALSEKERIIERLKEQRER-DDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLidl 646
Cdd:TIGR02169 759 E--------------LKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL--- 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 647 kehasslasagLKRDSKLKSLEIAIEQKKEECNKLEAQLKK-AHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAE 725
Cdd:TIGR02169 822 -----------NRLTLEKEYLEKEIQELQEQRIDLKEQIKSiEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE 890
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 726 VDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNAL 805
Cdd:TIGR02169 891 RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958683006 806 E----KTRQELDATKARLastqQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAA 858
Cdd:TIGR02169 971 EpvnmLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
260-902 |
1.74e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 78.64 E-value: 1.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 260 EENFRRLQAEHDRQAKELFLLRKTleEMELRIETQKQTLNARD-ESIKKLLEMLQSKGLpSKSLEDDNERTRRMAEAESQ 338
Cdd:PTZ00121 1137 EDARKAEEARKAEDAKRVEIARKA--EDARKAEEARKAEDAKKaEAARKAEEVRKAEEL-RKAEDARKAEAARKAEEERK 1213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 339 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEiQMLKANGVLNTED--RE 416
Cdd:PTZ00121 1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEkkKA 1292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 417 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESEllALQTKLETLSNQNSDCKQHIEVLK--ESLTAKEQRAAILQTEVDA 494
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAE--EAKKKADAAKKKAEEAKKAAEAAKaeAEAAADEAEAAEEKAEAAE 1370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKinvlQKKIENLQEQLRDKDKqltnlKDRVKSLQT 574
Cdd:PTZ00121 1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA----KKKADEAKKKAEEKKK-----ADEAKKKAE 1441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 575 DSSNTDTALATLEEAlSEKERIIERLKEQRERDDRERLEE----IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHA 650
Cdd:PTZ00121 1442 EAKKADEAKKKAEEA-KKAEEAKKKAEEAKKADEAKKKAEeakkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 651 SSLASAGLKRDSKLKSLEIaieQKKEECNKLEaQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKaQAEVDRLL 730
Cdd:PTZ00121 1521 AKKADEAKKAEEAKKADEA---KKAEEKKKAD-ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK-KAEEARIE 1595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 731 EILKEVENEKNDK--DKKIAELERHMKDQNKKVANLKHNQQLEKKKNAqllEEVRRREDSmvdnSQHLQIEELMNALEKT 808
Cdd:PTZ00121 1596 EVMKLYEEEKKMKaeEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA---EEKKKAEEL----KKAEEENKIKAAEEAK 1668
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 809 RQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEM------KQEALLAAISEKDANIALLELSASKKKKTQEE 882
Cdd:PTZ00121 1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKeaeekkKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
|
650 660
....*....|....*....|
gi 1958683006 883 VMALKREKDRLVHQLKQQTQ 902
Cdd:PTZ00121 1749 AKKDEEEKKKIAHLKKEEEK 1768
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
387-688 |
1.86e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 1.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 387 IASLERNIRDLEdeIQMLKANGVLNTEDREEEIkQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQnsd 466
Cdd:TIGR02168 195 LNELERQLKSLE--RQAEKAERYKELKAELREL-ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK--- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 467 ckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKER------- 539
Cdd:TIGR02168 269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEelaelee 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 540 KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFR 619
Cdd:TIGR02168 345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 620 KENKDLKE-KVNALQAELTEKESSLIDLKEHASSLASAglkrdskLKSLEIAIEQKKEECNKLEAQLKKA 688
Cdd:TIGR02168 425 ELLKKLEEaELKELQAELEELEEELEELQEELERLEEA-------LEELREELEEAEQALDAAERELAQL 487
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
222-906 |
6.14e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 6.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 222 QLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNAR 301
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGK 1110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 302 DESIKKLLEMLQSKGLPSKSLE-DDNERTRRMAEAESQVSHLEVILDQKEKENihLREELHRRSQLQPEPAKTKALQTVI 380
Cdd:PTZ00121 1111 AEEARKAEEAKKKAEDARKAEEaRKAEDARKAEEARKAEDAKRVEIARKAEDA--RKAEEARKAEDAKKAEAARKAEEVR 1188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 381 EMKDTKIASLERNIRDLEDEIQMLKANGVLNTED--REEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLE 458
Cdd:PTZ00121 1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDakKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARR 1268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 459 TLSNQNSDCKQHIEVLK--ESLTAKEQRAAILQTEVDALRLRLEEKesflnKKTKQLQDLTEEKGTLAGEIR----DMKD 532
Cdd:PTZ00121 1269 QAAIKAEEARKADELKKaeEKKKADEAKKAEEKKKADEAKKKAEEA-----KKADEAKKKAEEAKKKADAAKkkaeEAKK 1343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 533 MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL 612
Cdd:PTZ00121 1344 AAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEA 1423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 613 EEIESFRKENKDLKEKvnalqAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIaiEQKKEECNKLEAQLKKAHNIE 692
Cdd:PTZ00121 1424 KKKAEEKKKADEAKKK-----AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAK 1496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 693 ---DDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELErhmKDQNKKVANLKHNQQ 769
Cdd:PTZ00121 1497 kkaDEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELK---KAEEKKKAEEAKKAE 1573
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 770 LEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDA-TKARLASTQQSLAEKEAHLANLRMERRKQLEEIL 848
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAkIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 849 EMKQE-----ALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMK 906
Cdd:PTZ00121 1654 KAEEEnkikaAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
149-886 |
1.12e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.87 E-value: 1.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 149 DLQAQLKELQRENDLLRKELDIKDSKLgssmnsiktfwsPELKKE----RVLRKEEAARMSVLKEqmrvshEENQHLQLT 224
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEI------------SELEKRleeiEQLLEELNKKIKDLGE------EEQLRVKEK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 225 IQALQDELRTQRDLNHLLQQEsgnrgaehftIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRietqKQTLNARDES 304
Cdd:TIGR02169 296 IGELEAEIASLERSIAEKERE----------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR----RDKLTEEYAE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 305 IKKLLEMLQSKglpSKSLEDDNERTRrmaeaESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKD 384
Cdd:TIGR02169 362 LKEELEDLRAE---LEEVDKEFAETR-----DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 385 TKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVykshskfMKTKIDQLKQELSKKESELLALQTKLETLSNQN 464
Cdd:TIGR02169 434 AKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD-------LKEEYDRVEKELSKLQRELAEAEAQARASEERV 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 465 SDCKQHIEVLKESLTA-----------KEQRAAILQ-------------TEVDA------LRLRLEEKESF--LNKKTKQ 512
Cdd:TIGR02169 507 RGGRAVEEVLKASIQGvhgtvaqlgsvGERYATAIEvaagnrlnnvvveDDAVAkeaielLKRRKAGRATFlpLNKMRDE 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 513 LQDLteEKGTLAGEIRDMKDMLEVKERKINVL---------------------QKKIENLQEQLRDKDKQLTNLKDRVKS 571
Cdd:TIGR02169 587 RRDL--SILSEDGVIGFAVDLVEFDPKYEPAFkyvfgdtlvvedieaarrlmgKYRMVTLEGELFEKSGAMTGGSRAPRG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 572 LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLE----------EIESFRKENKDLKEKVNALQAELTEKES 641
Cdd:TIGR02169 665 GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDElsqelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEE 744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 642 SLidlkehaSSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKkahNIEDDSRMnpefaDRLKQLDKEASYYRDECGK 721
Cdd:TIGR02169 745 DL-------SSLEQEIENVKSELKELEARIEELEEDLHKLEEALN---DLEARLSH-----SRIPEIQAELSKLEEEVSR 809
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 722 AQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREdsmvdnSQHLQIEEL 801
Cdd:TIGR02169 810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE------AALRDLESR 883
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 802 MNALEKTRQELDATKARLASTQQSLAEkEAHLANLRMERRKQLEEILEMKQ---EALLAAISEKDANIALLELSASKKKK 878
Cdd:TIGR02169 884 LGDLKKERDELEAQLRELERKIEELEA-QIEKKRKRLSELKAKLEALEEELseiEDPKGEDEEIPEEELSLEDVQAELQR 962
|
....*...
gi 1958683006 879 TQEEVMAL 886
Cdd:TIGR02169 963 VEEEIRAL 970
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
578-893 |
4.57e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.94 E-value: 4.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 578 NTDTALATLEEALSEKERIIERLKEQRE--------RDDRERLE-------------EIESFRKENKDLKEKVNALQAEL 636
Cdd:TIGR02168 183 RTRENLDRLEDILNELERQLKSLERQAEkaerykelKAELRELElallvlrleelreELEELQEELKEAEEELEELTAEL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 637 TEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHN--------IEDDSRMNPEFADRLKQL 708
Cdd:TIGR02168 263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaqLEELESKLDELAEELAEL 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 709 DKEAsyyrdecGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKnaqlLEEVRRREDS 788
Cdd:TIGR02168 343 EEKL-------EELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE----IERLEARLER 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 789 MVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRmERRKQLEEILEMKQEALLAA---ISEKDAN 865
Cdd:TIGR02168 412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE-EALEELREELEEAEQALDAAereLAQLQAR 490
|
330 340
....*....|....*....|....*...
gi 1958683006 866 IALLELSASKKKKTQEEVMALKREKDRL 893
Cdd:TIGR02168 491 LDSLERLQENLEGFSEGVKALLKNQSGL 518
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
149-761 |
6.71e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.13 E-value: 6.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMN--SIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQ 226
Cdd:TIGR04523 163 DLKKQKEELENELNLLEKEKLNIQKNIDKIKNklLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEIN 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 227 ALQDEL-RTQRDLNHLLQQESGNRgaehftielteENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNArdESI 305
Cdd:TIGR04523 243 EKTTEIsNTQTQLNQLKDEQNKIK-----------KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ--DWN 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 306 KKLLEMLQSKGLPSKSLEDD-NERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpepaKTKALQTVIEMKD 384
Cdd:TIGR04523 310 KELKSELKNQEKKLEEIQNQiSQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQN------EIEKLKKENQSYK 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 385 TKIASLERNIRDLEDEIQMLKangvlntEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELlalqtklETLSNQN 464
Cdd:TIGR04523 384 QEIKNLESQINDLESKIQNQE-------KLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEI-------KDLTNQD 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 465 SDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerKINVL 544
Cdd:TIGR04523 450 SVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTK-------KISSL 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 545 QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDtalatLEEALSEKERIIERLKEQR---ERDDRERLEEIESFRKE 621
Cdd:TIGR04523 523 KEKIEKLESEKKEKESKISDLEDELNKDDFELKKEN-----LEKEIDEKNKEIEELKQTQkslKKKQEEKQELIDQKEKE 597
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 622 NKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKA-HNIEDDSRMNPE 700
Cdd:TIGR04523 598 KKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIiKKIKESKTKIDD 677
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958683006 701 FADRLKQLDKEASYYRDECGKAQ---AEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKV 761
Cdd:TIGR04523 678 IIELMKDWLKELSLHYKKYITRMiriKDLPKLEEKYKEIEKELKKLDEFSKELENIIKNFNKKF 741
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
156-828 |
8.58e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 73.25 E-value: 8.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 156 ELQRENDLLRKELDIKdsKLGSSMNSIKTFWSPELKKERVLRKEEAARMSvlKEQMRVSHEENQHLQLTIQALQ--DELR 233
Cdd:PTZ00121 1161 EDARKAEEARKAEDAK--KAEAARKAEEVRKAEELRKAEDARKAEAARKA--EEERKAEEARKAEDAKKAEAVKkaEEAK 1236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 234 TQRDLNHLLQQESGNRGAEHFTIELTEENFRR---LQAEHDRQAKELFLLRKTLEEMELRIETQKQTLnarDESIKKLLE 310
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRqaaIKAEEARKADELKKAEEKKKADEAKKAEEKKKA---DEAKKKAEE 1313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 311 MLQSKGLPSKSLEDDN--ERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIA 388
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKkaDAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 389 -SLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESEllalQTKLETLSNQNSDC 467
Cdd:PTZ00121 1394 dEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE----AKKAEEAKKKAEEA 1469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 468 KQHIEVLKESLTAKE-----QRAAILQTEVDALRLRLEEKesflnKKTKQLQDLTEEKGtlAGEIRDMKDMLEVKERKIN 542
Cdd:PTZ00121 1470 KKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAK-----KKADEAKKAEEAKK--ADEAKKAEEAKKADEAKKA 1542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 543 VLQKKIENLQ--EQLRDKDKqltnlKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIesfRK 620
Cdd:PTZ00121 1543 EEKKKADELKkaEELKKAEE-----KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA---KK 1614
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 621 ENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQ-LKKAhniEDDSRMNP 699
Cdd:PTZ00121 1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEeAKKA---EEDEKKAA 1691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 700 EFADRLKQLDKEAsyyrDECGKAQAEVDRLLEILKEVENEKNdkdKKIAELERHMKDQNKKVANLKHNQQlEKKKNAQLL 779
Cdd:PTZ00121 1692 EALKKEAEEAKKA----EELKKKEAEEKKKAEELKKAEEENK---IKAEEAKKEAEEDKKKAEEAKKDEE-EKKKIAHLK 1763
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 1958683006 780 EEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAE 828
Cdd:PTZ00121 1764 KEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
386-903 |
8.82e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 72.75 E-value: 8.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Cdd:TIGR04523 41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 466 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE-------IRDMKDMLEVKE 538
Cdd:TIGR04523 121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEklniqknIDKIKNKLLKLE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 539 RKINVLQKKIEN---LQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL----SEKERIIERLKEQRERDDR-- 609
Cdd:TIGR04523 201 LLLSNLKKKIQKnksLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLnqlkDEQNKIKKQLSEKQKELEQnn 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 610 -------ERLEEIESFRKENKDLKEKV--NALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNK 680
Cdd:TIGR04523 281 kkikeleKQLNQLKSEISDLNNQKEQDwnKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 681 LEAQLKKAHN-IEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNK 759
Cdd:TIGR04523 361 KQRELEEKQNeIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 760 KVANLKhNQQLEKKKNAQLLEEVRrredsmvdNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRME 839
Cdd:TIGR04523 441 EIKDLT-NQDSVKELIIKNLDNTR--------ESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK 511
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 840 RRKQLEEI--LEMKQEALLAAISEKDANIALLELSASKKK--KTQEEVMALKREKDRLVHQLKQQTQN 903
Cdd:TIGR04523 512 VKDLTKKIssLKEKIEKLESEKKEKESKISDLEDELNKDDfeLKKENLEKEIDEKNKEIEELKQTQKS 579
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
476-684 |
2.68e-12 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 69.79 E-value: 2.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 476 ESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL 555
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 556 rdkDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRerddRERLEEIESFRKENKDLKEKVNALQAE 635
Cdd:COG4942 100 ---EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLA----PARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1958683006 636 LTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQ 684
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
330-892 |
2.97e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 71.25 E-value: 2.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 330 RRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAK---------TKALQTVIEMKDTKIASLERNIRDLEDE 400
Cdd:TIGR02169 237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdlgeeeQLRVKEKIGELEAEIASLERSIAEKERE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 401 IqmlkangvlntEDREEEIKQIEVykshskfmktKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTA 480
Cdd:TIGR02169 317 L-----------EDAEERLAKLEA----------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 481 KEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDK 560
Cdd:TIGR02169 376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 561 QLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQReRDDRERLEEIESFRKENKDLKEKVNALQAELTEKE 640
Cdd:TIGR02169 456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVG 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 641 sslidlKEHASSLASAGLKRdskLKSLEIAIEQKKEECnkleAQLKKAHNIeddSRMNPEFADRLKQLDKEASY------ 714
Cdd:TIGR02169 535 ------ERYATAIEVAAGNR---LNNVVVEDDAVAKEA----IELLKRRKA---GRATFLPLNKMRDERRDLSIlsedgv 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 715 ---------YRDECGKAQAEVDRLLEILKEVENEKNDKDK-KIAELERHMKDQNKKV---ANLKHNQQLEKKKNAQLLEE 781
Cdd:TIGR02169 599 igfavdlveFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKyRMVTLEGELFEKSGAMtggSRAPRGGILFSRSEPAELQR 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 782 VRRRedsmvdnsqhlqIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRM-------------ERRKQLEEIL 848
Cdd:TIGR02169 679 LRER------------LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKeieqleqeeeklkERLEELEEDL 746
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1958683006 849 EMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDR 892
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH 790
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
227-647 |
3.66e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 70.84 E-value: 3.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 227 ALQDELRTQRDLNHLLQQESGNRGAEhftIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 306
Cdd:PRK02224 276 ELAEEVRDLRERLEELEEERDDLLAE---AGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 307 KLLEMLQSKGLPSKSLEDDNERTRR-MAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKalqtviEMKDT 385
Cdd:PRK02224 353 DLEERAEELREEAAELESELEEAREaVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER------DELRE 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 386 KIASLERNIRDLEDEI---QMLKANG--------------VLNTEDREEEIKQIEVYKSHskfMKTKIDQLKQELSKKEs 448
Cdd:PRK02224 427 REAELEATLRTARERVeeaEALLEAGkcpecgqpvegsphVETIEEDRERVEELEAELED---LEEEVEEVEERLERAE- 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 449 ELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE-- 526
Cdd:PRK02224 503 DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKla 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 527 -----------IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQT--DSSNTDTALATLEEALSEK 593
Cdd:PRK02224 583 elkerieslerIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefDEARIEEAREDKERAEEYL 662
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 594 ERIIERLKEQRERDD---------RERLEEIESFRKENKDLKEKVNALQA---ELTEKESSLIDLK 647
Cdd:PRK02224 663 EQVEEKLDELREERDdlqaeigavENELEELEELRERREALENRVEALEAlydEAEELESMYGDLR 728
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
191-890 |
4.63e-12 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 70.39 E-value: 4.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 191 KKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQAlQDELRTQRdlnhlLQQESGNRGAEHFTIELTEENFRRLQAEH 270
Cdd:pfam02463 170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQA-KKALEYYQ-----LKEKLELEEEYLLYLDYLKLNEERIDLLQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 271 DRQAKELFLLRKTLEEMELRIETQKQTLNARDEsIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKE 350
Cdd:pfam02463 244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKE-EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 351 KENIHLREELHRRSQLQPEPAKtKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSK 430
Cdd:pfam02463 323 KKKAEKELKKEKEEIEELEKEL-KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 431 FMKTKIDQLKQELSKKESELLALQTKLETLsnqnsdckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKT 510
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDLLKEEKKEELEI----------LEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 511 KQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD-RVKSLQTDSSNTDTALATLEEA 589
Cdd:pfam02463 472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHgRLGDLGVAVENYKVAISTAVIV 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 590 LSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669
Cdd:pfam02463 552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKD 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 670 AIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAE 749
Cdd:pfam02463 632 TELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 750 LERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEK 829
Cdd:pfam02463 712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 830 EAHlaNLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREK 890
Cdd:pfam02463 792 KEE--KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEK 850
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
220-861 |
5.71e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.09 E-value: 5.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 220 HLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHD---RQAKELFLLRKTLEEMELRIETQKQ 296
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEELEKELESLEG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 297 TLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpepaktkal 376
Cdd:PRK03918 253 SKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE----------- 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 377 qtviemkdtKIASLERNIRDLEDeiqmlKANGVLNTEDREEEI-KQIEVYKshskfmktKIDQLKQELSKKESELLALQT 455
Cdd:PRK03918 322 ---------EINGIEERIKELEE-----KEERLEELKKKLKELeKRLEELE--------ERHELYEEAKAKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 456 KLETLSnqnsdckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlE 535
Cdd:PRK03918 380 RLTGLT---------PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE--E 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 536 VKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNtdtalatlEEALSEKERIIERLKEQRERDDRERLEEI 615
Cdd:PRK03918 449 HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK--------ESELIKLKELAEQLKELEEKLKKYNLEEL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHasslasaglkrDSKLKSLEIAIEQKKEECNKLEAQLKKA--HNIED 693
Cdd:PRK03918 521 EKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEEL-----------KKKLAELEKKLDELEEELAELLKELEELgfESVEE 589
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 694 DSRmnpefadRLKQLDKeasYYRD--ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLE 771
Cdd:PRK03918 590 LEE-------RLKELEP---FYNEylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEE 659
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 772 KKKNAQLLEEVRRREDSMVDNsqhlQIEELMNALEKTRQELDATKARLASTQQslAEKEAHLANLRMERRKQL-EEILEM 850
Cdd:PRK03918 660 EYEELREEYLELSRELAGLRA----ELEELEKRREEIKKTLEKLKEELEEREK--AKKELEKLEKALERVEELrEKVKKY 733
|
650
....*....|.
gi 1958683006 851 KQEALLAAISE 861
Cdd:PRK03918 734 KALLKERALSK 744
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
265-911 |
8.40e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.70 E-value: 8.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 265 RLQAEhdrQAKELFLLRKTLEEMELRIET-QKQTLNARDESIKKLLEMLQskglpskslEDDNERTRRMAEAESQVSHLE 343
Cdd:TIGR02168 206 ERQAE---KAERYKELKAELRELELALLVlRLEELREELEELQEELKEAE---------EELEELTAELQELEEKLEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 344 VILDQKEKENIHLREELHRRSQlqpepaktkalqtviemkdtKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIE 423
Cdd:TIGR02168 274 LEVSELEEEIEELQKELYALAN--------------------EISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 424 VYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE--- 500
Cdd:TIGR02168 334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLErle 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 501 -EKESFLNKKTKQLQDLTE-EKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssN 578
Cdd:TIGR02168 414 dRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ----A 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 579 TDTALATLEEALSEKERIIERLKEQRER--DDRERLEEIESFRKENKDLKEKV--NALQAELTEKESSLID----LKEHA 650
Cdd:TIGR02168 490 RLDSLERLQENLEGFSEGVKALLKNQSGlsGILGVLSELISVDEGYEAAIEAAlgGRLQAVVVENLNAAKKaiafLKQNE 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 651 SSLAS---AGLKRDSKLKSLEIAIEQKKE-------ECNKLEAQLKKAHN---------------IEDDSRMNPEFadRL 705
Cdd:TIGR02168 570 LGRVTflpLDSIKGTEIQGNDREILKNIEgflgvakDLVKFDPKLRKALSyllggvlvvddldnaLELAKKLRPGY--RI 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 706 KQLD-----KEASYYRDECGKAQAEVDRLLEIlKEVENEKNDKDKKIAELERHMKDQNKKVANLKHN-QQLEKKKNAQLL 779
Cdd:TIGR02168 648 VTLDgdlvrPGGVITGGSAKTNSSILERRREI-EELEEKIEELEEKIAELEKALAELRKELEELEEElEQLRKELEELSR 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 780 EEVRRREDSMVDNSQHLQIEELMNALEKTRQELDA----TKARLASTQQSLAEKEAHLANLRMERRKQLEEIlemkqEAL 855
Cdd:TIGR02168 727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAeieeLEERLEEAEEELAEAEAEIEELEAQIEQLKEEL-----KAL 801
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 856 LAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADN 911
Cdd:TIGR02168 802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL 857
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
189-902 |
1.67e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 69.01 E-value: 1.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 189 ELKKERVLRKEEAARMSvlkEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQA 268
Cdd:PTZ00121 1114 ARKAEEAKKKAEDARKA---EEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKA 1190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 269 EHDRQAKELfllRKTLE----EMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEV 344
Cdd:PTZ00121 1191 EELRKAEDA---RKAEAarkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 345 ILDQKEKENIHLREELHRRSQLQP--EPAKTKALQTVIEMKdtKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQI 422
Cdd:PTZ00121 1268 RQAAIKAEEARKADELKKAEEKKKadEAKKAEEKKKADEAK--KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAA 1345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 423 EVYKSHSKFM---------KTKIDQLKQELSKKESEllALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAilQTEVD 493
Cdd:PTZ00121 1346 EAAKAEAEAAadeaeaaeeKAEAAEKKKEEAKKKAD--AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA--KKKAD 1421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 494 ALRLRLEEKESF--LNKKTKQLQDLTEEKGTlAGEIRDMKDMLEVKE--RKINVLQKKIENLQ--EQLRDKDKQLTNLKD 567
Cdd:PTZ00121 1422 EAKKKAEEKKKAdeAKKKAEEAKKADEAKKK-AEEAKKAEEAKKKAEeaKKADEAKKKAEEAKkaDEAKKKAEEAKKKAD 1500
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 568 RVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRK--ENKDLKEKVNALQAELTEKESSLID 645
Cdd:PTZ00121 1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKaeELKKAEEKKKAEEAKKAEEDKNMAL 1580
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 646 LK-EHASSLASAGLKRDSKLKSLEI---AIEQKKEECNKLEA-QLKKAH----NIEDDSRMNPEFADRLKQLDKEASYYR 716
Cdd:PTZ00121 1581 RKaEEAKKAEEARIEEVMKLYEEEKkmkAEEAKKAEEAKIKAeELKKAEeekkKVEQLKKKEAEEKKKAEELKKAEEENK 1660
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 717 ----DECGKAQAEVDRLLEILKEVENEkndkdKKIAELERHMKDQNKKVANLKHNQQLEKKKnaqlLEEVRRREDsmvdn 792
Cdd:PTZ00121 1661 ikaaEEAKKAEEDKKKAEEAKKAEEDE-----KKAAEALKKEAEEAKKAEELKKKEAEEKKK----AEELKKAEE----- 1726
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 793 SQHLQIEELmnaleKTRQELDATKARLASTQQSLAEKEAHlanLRMERRKQLEEILEMKQEALLAAISEKDANIALLELS 872
Cdd:PTZ00121 1727 ENKIKAEEA-----KKEAEEDKKKAEEAKKDEEEKKKIAH---LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
|
730 740 750
....*....|....*....|....*....|
gi 1958683006 873 ASKKKKTQEEVMALKREKDRLVHQLKQQTQ 902
Cdd:PTZ00121 1799 KIKDIFDNFANIIEGGKEGNLVINDSKEME 1828
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
198-791 |
3.15e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.44 E-value: 3.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 198 KEEAARMSVLKE--QMRVSHEENQHLQLTIQALQDElRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAK 275
Cdd:pfam05483 218 KEDHEKIQHLEEeyKKEINDKEKQVSLLLIQITEKE-NKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 276 ELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglpsksleddnERTRRMAEAESQVSHLEVILDQKEKENIH 355
Cdd:pfam05483 297 ELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTE----------------EKEAQMEELNKAKAAHSFVVTEFEATTCS 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 356 LREELHRRSQ-LQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIqmlkangvlntedreEEIKQIEVYKSHSKFMKT 434
Cdd:pfam05483 361 LEELLRTEQQrLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVEL---------------EELKKILAEDEKLLDEKK 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 435 KIDQLKQELSKKESELLALqtkLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ 514
Cdd:pfam05483 426 QFEKIAEELKGKEQELIFL---LQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 515 DLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQE---QLRDK----DKQLTNLKDRVKSLQTDSSNTDTALATLE 587
Cdd:pfam05483 503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEkemNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEYEV 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 588 EALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKEsslIDLKEHASSLASAGLKRDSKLKSL 667
Cdd:pfam05483 583 LKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYE---IKVNKLELELASAKQKFEEIIDNY 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 668 EIAIEQKKEECNKLEAQLKKAHNIED---------DSRMNPEFADRLKQLDKEASYYrdecGKAQAEVDRLLEILKEVEN 738
Cdd:pfam05483 660 QKEIEDKKISEEKLLEEVEKAKAIADeavklqkeiDKRCQHKIAEMVALMEKHKHQY----DKIIEERDSELGLYKNKEQ 735
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 739 EKNDKDkkiAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVD 791
Cdd:pfam05483 736 EQSSAK---AALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
583-893 |
4.85e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.40 E-value: 4.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 583 LATLEEALSEKERIIERLKEQRERDDR------ERLEEIESFRKEnKDLKEKVNALQAELTEKESSLI--DLKEHASSLA 654
Cdd:TIGR02169 162 IAGVAEFDRKKEKALEELEEVEENIERldliidEKRQQLERLRRE-REKAERYQALLKEKREYEGYELlkEKEALERQKE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 655 saglKRDSKLKSLEIAIEQKKEECNKLEAQLkkaHNIEDDSRmnpEFADRLKQL-DKEASYYRDECGKAQAEVDRLLEIL 733
Cdd:TIGR02169 241 ----AIERQLASLEEELEKLTEEISELEKRL---EEIEQLLE---ELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSI 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 734 KEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQhlQIEELMNALEKTRQELD 813
Cdd:TIGR02169 311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA--ELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 814 ATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQE------ALLAAISEKDANIALLELSASKKKKTQEEVMALK 887
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAiagieaKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468
|
....*.
gi 1958683006 888 REKDRL 893
Cdd:TIGR02169 469 QELYDL 474
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
256-639 |
5.62e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 5.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 256 IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRmaEA 335
Cdd:TIGR02168 679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK--EL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 336 ESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALqtviemkdtkIASLERNIRDLEDEIQMLKANGVLNTEDR 415
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE----------LKALREALDELRAELTLLNEEAANLRERL 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 416 EEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQnsdckqhIEVLKESLTAKEQRAAILQTEVDAL 495
Cdd:TIGR02168 827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE-------LEALLNERASLEEALALLRSELEEL 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 496 RLRLEEKESFLNKKTKQLQDLTEEKGTLageirdmkdmlevkERKINVLQKKIENLQEQLRDKDK-QLTNLKDRVKSLQT 574
Cdd:TIGR02168 900 SEELRELESKRSELRRELEELREKLAQL--------------ELRLEGLEVRIDNLQERLSEEYSlTLEEAEALENKIED 965
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958683006 575 DSSNTDTALATLEEALSEKERI----IERLKEQRERDDrERLEEIESFRKENKDLKEKVNALQAELTEK 639
Cdd:TIGR02168 966 DEEEARRRLKRLENKIKELGPVnlaaIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEIDREARER 1033
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
456-907 |
7.73e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 66.60 E-value: 7.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 456 KLETLSNQNSDCKQHIE-VLKESLTAKEQ-RAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM 533
Cdd:PRK02224 163 KLEEYRERASDARLGVErVLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 534 LEVKERK---INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQ----TDSSNTDTALATLEEALSEKERIIERLKEQRER 606
Cdd:PRK02224 243 LEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRerleELEEERDDLLAEAGLDDADAEAVEARREELEDR 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 607 DD--RERLEE----IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNK 680
Cdd:PRK02224 323 DEelRDRLEEcrvaAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGD 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 681 LEAQLKKAhniEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILK------EVENEK-----NDKDKKIAE 749
Cdd:PRK02224 403 APVDLGNA---EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqPVEGSPhvetiEEDRERVEE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 750 LERHMKDQNKKVANLkhNQQLEKKKNAQLLEEVRRREDSMVDNSQHLqIEELMNALEKTRQELDATKARLASTQQSLAEK 829
Cdd:PRK02224 480 LEAELEDLEEEVEEV--EERLERAEDLVEAEDRIERLEERREDLEEL-IAERRETIEEKRERAEELRERAAELEAEAEEK 556
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 830 EAHLANLRMERRKQLEEILEMKQEalLAAISEKDANIALLELSASKKKKTQEEVMALkreKDRLVHQLKQQTQNRMKL 907
Cdd:PRK02224 557 REAAAEAEEEAEEAREEVAELNSK--LAELKERIESLERIRTLLAAIADAEDEIERL---REKREALAELNDERRERL 629
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
284-863 |
1.13e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 66.08 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 284 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLP----SKSLEDDNERTRRMaeaESQVSHLEVILDQKEKENIHLREE 359
Cdd:PRK01156 164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLEleniKKQIADDEKSHSIT---LKEIERLSIEYNNAMDDYNNLKSA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 360 LHRRSQL-------QPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLnteDREEEIKQIEVYKSHSKFM 432
Cdd:PRK01156 241 LNELSSLedmknryESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYIN---DYFKYKNDIENKKQILSNI 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 433 KTKIDQLkQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESltakEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:PRK01156 318 DAEINKY-HAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGY----EMDYNSYLKSIESLKKKIEEYSKNIERMSAF 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 513 LQDLTEEKGTLAGEIRDMKDMLEVK----ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVK------SLQTDSSNT--- 579
Cdd:PRK01156 393 ISEILKIQEIDPDAIKKELNEINVKlqdiSSKVSSLNQRIRALRENLDELSRNMEMLNGQSVcpvcgtTLGEEKSNHiin 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 580 --DTALATLEEALSEKERIIERLKEQReRDDRERLEEIEsfrkenkdlKEKVNALQAE---LTEKESSLIDLKEHASSLA 654
Cdd:PRK01156 473 hyNEKKSRLEEKIREIEIEVKDIDEKI-VDLKKRKEYLE---------SEEINKSINEynkIESARADLEDIKIKINELK 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 655 SAGLKR---DSKLKSLEIAI-EQKKEECNKLEAQLKKAhNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLL 730
Cdd:PRK01156 543 DKHDKYeeiKNRYKSLKLEDlDSKRTSWLNALAVISLI-DIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSI 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 731 EILKEVENEKNDKDKKIAELERHMKDQNKKVANLKhnQQLEKKKNaqlleevrRREDSMVDNSQHLQIEELMNALEKTRQ 810
Cdd:PRK01156 622 REIENEANNLNNKYNEIQENKILIEKLRGKIDNYK--KQIAEIDS--------IIPDLKEITSRINDIEDNLKKSRKALD 691
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 811 ELDATKARLASTQQSLAEKEAHLANLRMERRKQLEeilemKQEALLAAISEKD 863
Cdd:PRK01156 692 DAKANRARLESTIEILRTRINELSDRINDINETLE-----SMKKIKKAIGDLK 739
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
503-688 |
1.70e-10 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 64.08 E-value: 1.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 503 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLT-----------NLKDRVKS 571
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaeaeieerreELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 572 LQTDSSNTDTALATLE----EALSEKERIIERLKEQrerdDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647
Cdd:COG3883 95 LYRSGGSVSYLDVLLGsesfSDFLDRLSALSKIADA----DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1958683006 648 EhasSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKA 688
Cdd:COG3883 171 A---ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
433-641 |
1.97e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 64.01 E-value: 1.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 433 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 513 LQDL------TEEKGTL-----AGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 581
Cdd:COG4942 106 LAELlralyrLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 582 ALATLEEALSEKERIIERLKEQRERDDrerlEEIESFRKENKDLKEKVNALQAELTEKES 641
Cdd:COG4942 186 ERAALEALKAERQKLLARLEKELAELA----AELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
148-752 |
5.74e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.80 E-value: 5.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 148 LDLQAQLKELQREndLLRKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARMSVLKEQMRVSHEEnqhLQLTIQA 227
Cdd:COG1196 216 RELKEELKELEAE--LLLLKLRELEAELEELEAELE-----ELEAELEELEAELAELEAELEELRLELEE---LELELEE 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 228 LQDEL--------RTQRDLNHL---LQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQ 296
Cdd:COG1196 286 AQAEEyellaelaRLEQDIARLeerRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 297 TLNARDESIKKLLEMLQSKglpsksLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpepAKTKAL 376
Cdd:COG1196 366 ALLEAEAELAEAEEELEEL------AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE-----ALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 377 QTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKfmKTKIDQLKQELSKKESELLALQTK 456
Cdd:COG1196 435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 457 LETLSNQnsdCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEV 536
Cdd:COG1196 513 ALLLAGL---RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 537 KERKINVLQKKIENLQEQLRDKDKQLTNLKDrvkSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERddRERLEEIE 616
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGD---TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG--SAGGSLTG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 617 SFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSR 696
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 697 MNPEFADRLKQLDKEASY--YRDECGKAQAEVDRL-------LEILKEVENEKNDKDKKIAELER 752
Cdd:COG1196 745 EELLEEEALEELPEPPDLeeLERELERLEREIEALgpvnllaIEEYEELEERYDFLSEQREDLEE 809
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
704-899 |
7.32e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 62.09 E-value: 7.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 704 RLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVR 783
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 784 RREDSMVDNSQHLQIEELMN-------------------ALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQl 844
Cdd:COG4942 108 ELLRALYRLGRQPPLALLLSpedfldavrrlqylkylapARREQAEELRADLAELAALRAELEAERAELEALLAELEEE- 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 845 eeilemkQEALLAAISEKDANIALLElsaSKKKKTQEEVMALKREKDRLVHQLKQ 899
Cdd:COG4942 187 -------RAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIAR 231
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
432-897 |
8.68e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 63.01 E-value: 8.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 432 MKTKIDQLK---QELSKKESELLALQTKLETLSNQNSDCKQHIEvLKESLTAKEQRAAIL-----QTEVDALRLRLEEKE 503
Cdd:COG4913 223 TFEAADALVehfDDLERAHEALEDAREQIELLEPIRELAERYAA-ARERLAELEYLRAALrlwfaQRRLELLEAELEELR 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 504 SFLNKKTKQLQDLTEEKGTLAGEIRDMK-DMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA 582
Cdd:COG4913 302 AELARLEAELERLEARLDALREELDELEaQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEE 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 583 LATL----EEALSEKERIIERLKEQ------RERDDRERLE----EIESFRKENKDLKEKV----NALQAELTEKESS-- 642
Cdd:COG4913 382 FAALraeaAALLEALEEELEALEEAlaeaeaALRDLRRELReleaEIASLERRKSNIPARLlalrDALAEALGLDEAElp 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 643 ----LIDLKEHASS--------LASAGL-------------------KRDSKLKSLEIAIEQKKEECNKLEAQ-----LK 686
Cdd:COG4913 462 fvgeLIEVRPEEERwrgaiervLGGFALtllvppehyaaalrwvnrlHLRGRLVYERVRTGLPDPERPRLDPDslagkLD 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 687 -KAHNIED--DSRMNPEFA----DRLKQLDKEA-----------SYYRDECGK-------------AQAEVDRLLEILKE 735
Cdd:COG4913 542 fKPHPFRAwlEAELGRRFDyvcvDSPEELRRHPraitragqvkgNGTRHEKDDrrrirsryvlgfdNRAKLAALEAELAE 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 736 VENEKNDKDKKIAELERHMKDQNKKVANLKHNQQL--EKKKNAQLLEEVRRRED---SMVDNSQHL-----QIEELMNAL 805
Cdd:COG4913 622 LEEELAEAEERLEALEAELDALQERREALQRLAEYswDEIDVASAEREIAELEAeleRLDASSDDLaaleeQLEELEAEL 701
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 806 EKTRQELDATKARLASTQQSLAEKEAHLANLRMerrkQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMA 885
Cdd:COG4913 702 EELEEELDELKGEIGRLEKELEQAEEELDELQD----RLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDA 777
|
570
....*....|..
gi 1958683006 886 LKREKDRLVHQL 897
Cdd:COG4913 778 LRARLNRAEEEL 789
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
510-853 |
1.86e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 61.96 E-value: 1.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 510 TKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 589
Cdd:TIGR04523 39 EKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 590 LSEKERIIERLKEQRERDDRER---LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKS 666
Cdd:TIGR04523 119 KNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLK 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 667 LEI---AIEQKKEECNKLEAQlkkahnIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDK 743
Cdd:TIGR04523 199 LELllsNLKKKIQKNKSLESQ------ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEK 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 744 DKKIAELERHMKDQNKKVANLKH-----NQQLEKKKNAQLLEEVRRREDSMVD-NSQHLQIEELMNALEKTRQELDATKA 817
Cdd:TIGR04523 273 QKELEQNNKKIKELEKQLNQLKSeisdlNNQKEQDWNKELKSELKNQEKKLEEiQNQISQNNKIISQLNEQISQLKKELT 352
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1958683006 818 RLASTQQS----LAEKEAHLANLRMERRKQLEEILEMKQE 853
Cdd:TIGR04523 353 NSESENSEkqreLEEKQNEIEKLKKENQSYKQEIKNLESQ 392
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
151-810 |
4.23e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 60.83 E-value: 4.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 151 QAQLKELQRENDLLRKELDIKDSKLGSSMNS----IKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQ 226
Cdd:TIGR00606 425 QEQADEIRDEKKGLGRTIELKKEILEKKQEElkfvIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVK 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 227 ALQDE----LRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKqTLNARD 302
Cdd:TIGR00606 505 SLQNEkadlDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED-WLHSKS 583
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 303 ESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEA-ESQVSHLEVIL------DQKEKENIHLREELHR-RSQLQPEPAKTK 374
Cdd:TIGR00606 584 KEINQTRDRLAKLNKELASLEQNKNHINNELESkEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKsSKQRAMLAGATA 663
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 375 ALQTVIEMKDTKIAS-------LERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Cdd:TIGR00606 664 VYSQFITQLTDENQSccpvcqrVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 448 SELLALQTKLETLSNQNSDCKQHI---EVLKESLTAKEQRAAILQTEV---DALRLRLEEKESFLNKKTKQLQ--DLTEE 519
Cdd:TIGR00606 744 KEIPELRNKLQKVNRDIQRLKNDIeeqETLLGTIMPEEESAKVCLTDVtimERFQMELKDVERKIAQQAAKLQgsDLDRT 823
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 520 KGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIER 599
Cdd:TIGR00606 824 VQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIRE 903
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 600 LKEQR----------ERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKrdsklkslei 669
Cdd:TIGR00606 904 IKDAKeqdspletflEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLK---------- 973
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 670 aieQKKEECNKLEAQLKKahNIEDDSRMNPEFadRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAE 749
Cdd:TIGR00606 974 ---QKETELNTVNAQLEE--CEKHQEKINEDM--RLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ 1046
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958683006 750 LE-RHMKDQNKKvanLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQ 810
Cdd:TIGR00606 1047 MQvLQMKQEHQK---LEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYRE 1105
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
413-659 |
5.25e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.39 E-value: 5.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 413 EDREEEIKQIevykshskfmKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEV 492
Cdd:COG4942 23 AEAEAELEQL----------QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 493 DALRLRLEEKESFLNKKTKQLQDL-TEEKGTLAGEIRDMKDMLevkeRKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAV----RRLQYLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 572 LQTDSsntdTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 651
Cdd:COG4942 169 LEAER----AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
|
....*...
gi 1958683006 652 SLASAGLK 659
Cdd:COG4942 245 AAGFAALK 252
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
433-901 |
5.82e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 60.14 E-value: 5.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 433 KTKIDQLKQELSKK-----------ESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 501
Cdd:pfam05557 8 KARLSQLQNEKKQMelehkrarielEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 502 KESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSntdt 581
Cdd:pfam05557 88 LNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQS---- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 582 ALATLEEALSEKERIIERLKEQRE--RDDRERLEEIESFRKENKDLKEKVNALQaelTEKESSLIdLKEHASSLaSAGLK 659
Cdd:pfam05557 164 SLAEAEQRIKELEFEIQSQEQDSEivKNSKSELARIPELEKELERLREHNKHLN---ENIENKLL-LKEEVEDL-KRKLE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 660 RDSKLKSLEIAIEQKKEecnKLEAQLKKAHNIEDDSRMN---PE-FADRLKQLDKEASYYRDECGKAQAEVDRLLEILKE 735
Cdd:pfam05557 239 REEKYREEAATLELEKE---KLEQELQSWVKLAQDTGLNlrsPEdLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 736 VENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDAT 815
Cdd:pfam05557 316 LEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQLLERIEEAEDMTQKMQAH 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 816 KARLaSTQQSLAEKEAhlanlrmERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKK--KTQEEVMALKREKDRL 893
Cdd:pfam05557 396 NEEM-EAQLSVAEEEL-------GGYKQQAQTLERELQALRQQESLADPSYSKEEVDSLRRKleTLELERQRLREQKNEL 467
|
....*...
gi 1958683006 894 VHQLKQQT 901
Cdd:pfam05557 468 EMELERRC 475
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
224-865 |
7.39e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 60.06 E-value: 7.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 224 TIQALQDELRTQR-DLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQK-QTLNAR 301
Cdd:TIGR00606 423 LKQEQADEIRDEKkGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLtETLKKE 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 302 DESIKKL-LEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELhrrSQLQPEPAKTKALQTVI 380
Cdd:TIGR00606 503 VKSLQNEkADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEL---TSLLGYFPNKKQLEDWL 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 381 EMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSH------SKFMKTKIDQLKQELSKKESELLALQ 454
Cdd:TIGR00606 580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEESDLERLKEEIEKSSKQRAMLA 659
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 455 TK-------LETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEI 527
Cdd:TIGR00606 660 GAtavysqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 528 -RDMKDMLEVKERKINVlQKKIENLQEQLRDKDKQLTNLKDRVKS---LQTDSsntdTALATLEEALSEKERIIERL--- 600
Cdd:TIGR00606 740 dLKEKEIPELRNKLQKV-NRDIQRLKNDIEEQETLLGTIMPEEESakvCLTDV----TIMERFQMELKDVERKIAQQaak 814
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 601 --------------KEQRERDDRER--LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS---SLASAGLKRD 661
Cdd:TIGR00606 815 lqgsdldrtvqqvnQEKQEKQHELDtvVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQrrqQFEEQLVELS 894
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 662 SKLKSLEIAIEQKKEECNKLEAQLKK---------AHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLei 732
Cdd:TIGR00606 895 TEVQSLIREIKDAKEQDSPLETFLEKdqqekeeliSSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYL-- 972
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 733 lKEVENEKNDKDKKIAELERHMKDQNKKVANLKHN------------QQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEE 800
Cdd:TIGR00606 973 -KQKETELNTVNAQLEECEKHQEKINEDMRLMRQDidtqkiqerwlqDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQ 1051
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958683006 801 LMNALEKTRQELDATKAR--LASTQQSLAEKEAHLANLRMeRRKQLEEILEMKQEALLAAISEKDAN 865
Cdd:TIGR00606 1052 MKQEHQKLEENIDLIKRNhvLALGRQKGYEKEIKHFKKEL-REPQFRDAEEKYREMMIVMRTTELVN 1117
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
483-884 |
7.71e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.78 E-value: 7.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 483 QRAAILQTEVDALRLRL---EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQ--KKIENLQEQLRD 557
Cdd:COG4717 64 RKPELNLKELKELEEELkeaEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 558 KDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELT 637
Cdd:COG4717 144 LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 638 EKESSLIDLKEH-------------------ASSLASAGLKRDSKLKSLE---------------IAIEQKKEECNKLEA 683
Cdd:COG4717 224 ELEEELEQLENEleaaaleerlkearlllliAAALLALLGLGGSLLSLILtiagvlflvlgllalLFLLLAREKASLGKE 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 684 QLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVAN 763
Cdd:COG4717 304 AEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 764 -------LKHNQQLEKKKN--AQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLA 834
Cdd:COG4717 384 eeelraaLEQAEEYQELKEelEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELE 463
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 1958683006 835 nlRMERRKQLEEILEmKQEALLAAISEKDANIALLELSASKKKKTQEEVM 884
Cdd:COG4717 464 --QLEEDGELAELLQ-ELEELKAELRELAEEWAALKLALELLEEAREEYR 510
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
433-642 |
7.97e-09 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 59.07 E-value: 7.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 433 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:COG3883 22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 513 LQDLT-----EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssntdTALATLE 587
Cdd:COG3883 102 VSYLDvllgsESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE-------AAKAELE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 588 EALSEKERIIERLKEQRerddRERLEEIESFRKENKDLKEKVNALQAELTEKESS 642
Cdd:COG3883 175 AQQAEQEALLAQLSAEE----AAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
663-910 |
8.93e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 59.70 E-value: 8.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 663 KLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASyyRDECGKAQAEVDRLLEILKEVENEKND 742
Cdd:TIGR02169 185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEAL--ERQKEAIERQLASLEEELEKLTEEISE 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 743 KDKKIAELERHMKDQNKKVANLKHNQQLE-KKKNAQLLEEVRRREDSMVDNSQhlQIEELMNALEKTRQELDATKARLAS 821
Cdd:TIGR02169 263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKER--ELEDAEERLAKLEAEIDKLLAEIEE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 822 TQQSLAEKeahlanlRMERRKQLEEILEMKQE--ALLAAISEKDANIALL--ELSASKKK--KTQEEVMALKREKDRLVH 895
Cdd:TIGR02169 341 LEREIEEE-------RKRRDKLTEEYAELKEEleDLRAELEEVDKEFAETrdELKDYREKleKLKREINELKRELDRLQE 413
|
250
....*....|....*
gi 1958683006 896 QLKQQTQNRMKLMAD 910
Cdd:TIGR02169 414 ELQRLSEELADLNAA 428
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
386-606 |
1.71e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.85 E-value: 1.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVykshskfMKTKIDQLKQELSKKESELLALQTKLETLSNQNS 465
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA-------LERRIAALARRIRALEQELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 466 DCKQHIEVLKESLtAKEQRAAILQTEVDALRLRLEEKESF-LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL 544
Cdd:COG4942 94 ELRAELEAQKEEL-AELLRALYRLGRQPPLALLLSPEDFLdAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 545 QKKIENLQEQLRDKDKQLTNLKDR----VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER 606
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
487-898 |
1.75e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.92 E-value: 1.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 487 ILQTEVDALRLRLEEKESFLnKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKInvlqKKIENLQEQLRDKDKQLTNLK 566
Cdd:PRK03918 132 IRQGEIDAILESDESREKVV-RQILGLDDYENAYKNLGEVIKEIKRRIERLEKFI----KRTENIEELIKEKEKELEEVL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 567 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQR-------------ERDDRERLEEIESFRKENKDLKEKVNALQ 633
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEkeleslegskrklEEKIRELEERIEELKKEIEELEEKVKELK 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 634 A--ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQL----KKAHNIEDDSRMNPEFA---DR 704
Cdd:PRK03918 287 ElkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLeelkKKLKELEKRLEELEERHelyEE 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 705 LKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNqqLEKKKNAQLLEEVRR 784
Cdd:PRK03918 367 AKAKKEELERLKKR--LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKA--IEELKKAKGKCPVCG 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 785 REdsmvdnsqhLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDA 864
Cdd:PRK03918 443 RE---------LTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLK 513
|
410 420 430
....*....|....*....|....*....|....*.
gi 1958683006 865 NIALLELSASKKK--KTQEEVMALKREKDRLVHQLK 898
Cdd:PRK03918 514 KYNLEELEKKAEEyeKLKEKLIKLKGEIKSLKKELE 549
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
187-907 |
2.49e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 58.44 E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 187 SPELKKERVLRKEEAARMSVLKEQMRVS-HEENQHLQLTIQALQDELRTQRDLNHLLQQESgnrgaehftiELTEENFRR 265
Cdd:TIGR00618 189 KKSLHGKAELLTLRSQLLTLCTPCMPDTyHERKQVLEKELKHLREALQQTQQSHAYLTQKR----------EAQEEQLKK 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 266 LQA--EHDRQAKELFLLRKTLEEMELRIETQKQTLNARDES---------IKKLLEMLQSK-GLPSKSLEDDNERTRRMA 333
Cdd:TIGR00618 259 QQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIkavtqieqqAQRIHTELQSKmRSRAKLLMKRAAHVKQQS 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 334 EAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMK--DTKIASLERNIRDLEDEIQmlkanGVLN 411
Cdd:TIGR00618 339 SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKttLTQKLQSLCKELDILQREQ-----ATID 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 412 TEDREEEIKQIEVYKSHSKF-MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRaaiLQT 490
Cdd:TIGR00618 414 TRTSAFRDLQGQLAHAKKQQeLQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR---KKA 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 491 EVDALRLRLEEKESFLNKKTKQLqdltEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVK 570
Cdd:TIGR00618 491 VVLARLLELQEEPCPLCGSCIHP----NPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQ 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 571 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTE--KESSLIDLKE 648
Cdd:TIGR00618 567 EIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLqqCSQELALKLT 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 649 HASSLASAGLKRDSKLKSLEIAiEQKKEECNKLEAQLKKAHNIEddsrmnpefadRLKQLDKEASYYRDEcgKAQAEVDR 728
Cdd:TIGR00618 647 ALHALQLTLTQERVREHALSIR-VLPKELLASRQLALQKMQSEK-----------EQLTYWKEMLAQCQT--LLRELETH 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 729 LLEILKEVENEKNDKDKKIAELErhmkdqnkkvANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNA-LEK 807
Cdd:TIGR00618 713 IEEYDREFNEIENASSSLGSDLA----------AREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAeLSH 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 808 TRQELDATKARLASTQQSLAEKEAHLAnlrmERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALK 887
Cdd:TIGR00618 783 LAAEIQFFNRLREEDTHLLKTLEAEIG----QEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECS 858
|
730 740
....*....|....*....|
gi 1958683006 888 REKDRLVHQLKQQTQNRMKL 907
Cdd:TIGR00618 859 KQLAQLTQEQAKIIQLSDKL 878
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
320-930 |
2.88e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 58.06 E-value: 2.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 320 KSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLED 399
Cdd:pfam02463 200 LKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 400 EIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLT 479
Cdd:pfam02463 280 EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 480 AKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKE----RKINVLQKKIENLQEQL 555
Cdd:pfam02463 360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEdllkEEKKEELEILEEEEESI 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 556 RDKDKQLTNLKDRVKsLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAE 635
Cdd:pfam02463 440 ELKQGKLTEEKEELE-KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKD 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 636 LTEKESSLIDLKEHASSLASAGLKRD--SKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEAS 713
Cdd:pfam02463 519 GVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLE 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 714 --YYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQ--LEKKKNAQLLEEVRRREDSM 789
Cdd:pfam02463 599 idPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEglAEKSEVKASLSELTKELLEI 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 790 VDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALL 869
Cdd:pfam02463 679 QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK 758
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 870 ELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRS 930
Cdd:pfam02463 759 KEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEE 819
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
511-752 |
4.12e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 57.62 E-value: 4.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 511 KQLQDLTEEkgtlageIRDMkdMLEVKErkinvLQKKIENLQEQLRDKD---KQLTNLKDRVKSLQtDSSNTDTALATLE 587
Cdd:COG4913 204 KPIGDLDDF-------VREY--MLEEPD-----TFEAADALVEHFDDLErahEALEDAREQIELLE-PIRELAERYAAAR 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 588 EALSEKERIIERLK-EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasSLASAGLKR----DS 662
Cdd:COG4913 269 ERLAELEYLRAALRlWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNGGDRleqlER 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 663 KLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRmnPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKND 742
Cdd:COG4913 346 EIERLERELEERERRRARLEALLAALGLPLPASA--EEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE 423
|
250
....*....|
gi 1958683006 743 KDKKIAELER 752
Cdd:COG4913 424 LEAEIASLER 433
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
266-734 |
4.95e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 57.54 E-value: 4.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 266 LQAEHDRQAKELfllRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSledDNERTRRMAEAESQVSHLEVI 345
Cdd:pfam12128 424 LREQLEAGKLEF---NEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERA---REEQEAANAEVERLQSELRQA 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 346 LDQKEKENIHLREELHRRSQLQPEPAKTK-----ALQTVIEMKDTKIASLERNI-----------RDLEDEIQMLKANGV 409
Cdd:pfam12128 498 RKRRDQASEALRQASRRLEERQSALDELElqlfpQAGTLLHFLRKEAPDWEQSIgkvispellhrTDLDPEVWDGSVGGE 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 410 LNTEDREEEIKQIEV--YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAI 487
Cdd:pfam12128 578 LNLYGVKLDLKRIDVpeWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRR 657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 488 LQTEVDALRLRLEEK-ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlEVKERKINVLQKKIENLQEQLRDKDKQL---- 562
Cdd:pfam12128 658 LFDEKQSEKDKKNKAlAERKDSANERLNSLEAQLKQLDKKHQAWLE--EQKEQKREARTEKQAYWQVVEGALDAQLallk 735
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 563 -------TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAE 635
Cdd:pfam12128 736 aaiaarrSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQ 815
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 636 LTEKESSLIDLKEHASSLASAGLKRDSKL----KSLEIAIEQKKEECNKLEAQLKKA---HNIEDDSRMNPEFADRLKQL 708
Cdd:pfam12128 816 LSNIERAISELQQQLARLIADTKLRRAKLemerKASEKQQVRLSENLRGLRCEMSKLatlKEDANSEQAQGSIGERLAQL 895
|
490 500
....*....|....*....|....*.
gi 1958683006 709 DKEASYYRDECGKAQAEVDRLLEILK 734
Cdd:pfam12128 896 EDLKLKRDYLSESVKKYVEHFKNVIA 921
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
148-639 |
5.69e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 57.23 E-value: 5.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 148 LDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARmsvLKEQMR-VSHEENQHLQLTIQ 226
Cdd:COG4913 277 LRAALRLWFAQRRLELLEAELEELRAELARLEAELE-----RLEARLDALREELDE---LEAQIRgNGGDRLEQLEREIE 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 227 ALQDELRTQRdlNHLLQQESGNRGAeHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 306
Cdd:COG4913 349 RLERELEERE--RRRARLEALLAAL-GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 307 KLLEMLQSKGlpsKSLEDDNERTRRMAEAESQVS---------HLEVILDQK------EK-------------------- 351
Cdd:COG4913 426 AEIASLERRK---SNIPARLLALRDALAEALGLDeaelpfvgeLIEVRPEEErwrgaiERvlggfaltllvppehyaaal 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 352 ---ENIHLREELH------RRSQLQPEPAKTKALQTVIEMKDTKI-----ASLER--------NIRDLEDEIQ------M 403
Cdd:COG4913 503 rwvNRLHLRGRLVyervrtGLPDPERPRLDPDSLAGKLDFKPHPFrawleAELGRrfdyvcvdSPEELRRHPRaitragQ 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 404 LKANGVLNTEDREEEIKQIEVYKSHSKfmkTKIDQLKQELSKKESELLALQTKLETLsnqnsdcKQHIEVLKESLTAKEQ 483
Cdd:COG4913 583 VKGNGTRHEKDDRRRIRSRYVLGFDNR---AKLAALEAELAELEEELAEAEERLEAL-------EAELDALQERREALQR 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 484 RAAILQTEVD--ALRLRLEEKEsflnkktKQLQDLTEEKGTLAGeirdMKDMLEVKERKINVLQKKIENLQEQLRDKDKQ 561
Cdd:COG4913 653 LAEYSWDEIDvaSAEREIAELE-------AELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKE 721
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 562 LTNLKDRVKSLQTDSSNTDTALATLEEALSEkERIIERLKEQRERDDRERLEEiesfrkENKDLKEKVNALQAELTEK 639
Cdd:COG4913 722 LEQAEEELDELQDRLEAAEDLARLELRALLE-ERFAAALGDAVERELRENLEE------RIDALRARLNRAEEELERA 792
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
145-605 |
7.57e-08 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 56.67 E-value: 7.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 145 STMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLT 224
Cdd:pfam05557 9 ARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 225 IQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRI---ETQKQTLNAR 301
Cdd:pfam05557 89 NKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRqnlEKQQSSLAEA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 302 DESIKKLLEMLQSKglpskslEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIE 381
Cdd:pfam05557 169 EQRIKELEFEIQSQ-------EQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 382 MKDTKIASLERNIRDLEDEIQM---LKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLE 458
Cdd:pfam05557 242 KYREEAATLELEKEKLEQELQSwvkLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 459 TLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNkKTKQLQDLTEEKGTLAGEIRDMKDMLEVKE 538
Cdd:pfam05557 322 QYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELT-MSNYSPQLLERIEEAEDMTQKMQAHNEEME 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958683006 539 RKINVLQKKIENLQEQLRDKDKQLTNLKDrvKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE 605
Cdd:pfam05557 401 AQLSVAEEELGGYKQQAQTLERELQALRQ--QESLADPSYSKEEVDSLRRKLETLELERQRLREQKN 465
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
417-628 |
1.01e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 55.79 E-value: 1.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 417 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLET----------LSNQNSDCKQHI--EVLKESLTAKEQR 484
Cdd:PHA02562 157 EDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTynknieeqrkKNGENIARKQNKydELVEEAKTIKAEI 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 485 AAiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE----------------IRDMKDMLEVKERKINVLQKKI 548
Cdd:PHA02562 237 EE-LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVikmyekggvcptctqqISEGPDRITKIKDKLKELQHSL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 549 ENL---QEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDrerlEEIESFRKENKDL 625
Cdd:PHA02562 316 EKLdtaIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNA----EELAKLQDELDKI 391
|
...
gi 1958683006 626 KEK 628
Cdd:PHA02562 392 VKT 394
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
565-808 |
1.15e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 55.79 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 565 LKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQrERDDRERLEE-IESFRKENKDLKEKVNALQAELTEKESSL 643
Cdd:PHA02562 172 NKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKK-NGENIARKQNkYDELVEEAKTIKAEIEELTDELLNLVMDI 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 644 IDLKEHAsslasaglkrdSKLKSLEIAIEQKKEECNKLEAQLKKAH-------NIEDDSRMNPEFADRLKQLDKEasyyr 716
Cdd:PHA02562 251 EDPSAAL-----------NKLNTAAAKIKSKIEQFQKVIKMYEKGGvcptctqQISEGPDRITKIKDKLKELQHS----- 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 717 decgkaqaevdrlLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQhl 796
Cdd:PHA02562 315 -------------LEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAE-- 379
|
250
....*....|..
gi 1958683006 797 QIEELMNALEKT 808
Cdd:PHA02562 380 ELAKLQDELDKI 391
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
273-524 |
1.27e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 1.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 273 QAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLqskglpsKSLEDD-NERTRRMAEAESQVSHLEVILDQKEK 351
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-------AALERRiAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 352 ENIHLREELHRRSQLQpepakTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREeeikQIEVYKSHSKF 431
Cdd:COG4942 91 EIAELRAELEAQKEEL-----AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 432 MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE--EKESFLNKK 509
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIArlEAEAAAAAE 241
|
250
....*....|....*
gi 1958683006 510 TKQLQDLTEEKGTLA 524
Cdd:COG4942 242 RTPAAGFAALKGKLP 256
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
432-631 |
1.33e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 53.78 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 432 MKTKIDQLKqELSKKESELLALQTKLETLsnqnsdcKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLnkktK 511
Cdd:COG1579 2 MPEDLRALL-DLQELDSELDRLEHRLKEL-------PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI----E 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 512 QLQDLTEEKGTLAGEIRDMKDMlevkerkiNVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssntdTALATLEEALS 591
Cdd:COG1579 70 EVEARIKKYEEQLGNVRNNKEY--------EALQKEIESLKRRISDLEDEILELMERIEELE-------EELAELEAELA 134
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1958683006 592 EKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNA 631
Cdd:COG1579 135 ELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
205-444 |
1.36e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 55.41 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 205 SVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTI--ELTEENfRRLQAEHDRQAKELFLLRK 282
Cdd:PHA02562 170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKydELVEEA-KTIKAEIEELTDELLNLVM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 283 TLEEME---LRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILdqkEKENIHLREE 359
Cdd:PHA02562 249 DIEDPSaalNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSL---EKLDTAIDEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 360 LHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVlnteDREEEIKQIEVYKSHSKFMKTKIDQL 439
Cdd:PHA02562 326 EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV----DNAEELAKLQDELDKIVKTKSELVKE 401
|
....*
gi 1958683006 440 KQELS 444
Cdd:PHA02562 402 KYHRG 406
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
346-595 |
1.60e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 1.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 346 LDQKEKENIHLREELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLkangvlntedrEEEIKQIEv 424
Cdd:COG4942 22 AAEAEAELEQLQQEIAElEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL-----------EAELAELE- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 425 ykshskfmkTKIDQLKQELSKKESELLALQTKLETLSNQNSdckqhIEVL--KESLTAKEQRAAILQTEVDALRLRLEEk 502
Cdd:COG4942 90 ---------KEIAELRAELEAQKEELAELLRALYRLGRQPP-----LALLlsPEDFLDAVRRLQYLKYLAPARREQAEE- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 503 esfLNKKTKQLQDLTEEkgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA 582
Cdd:COG4942 155 ---LRADLAELAALRAE---LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
250
....*....|...
gi 1958683006 583 LATLEEALSEKER 595
Cdd:COG4942 229 IARLEAEAAAAAE 241
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
538-687 |
2.05e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 53.00 E-value: 2.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 538 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQ-------RERDDRE 610
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnvrnnKEYEALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 611 RleEIESFRKENKDLKEKVNALQAELTEKESSLID----LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK 686
Cdd:COG1579 96 K--EIESLKRRISDLEDEILELMERIEELEEELAEleaeLAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
|
.
gi 1958683006 687 K 687
Cdd:COG1579 174 P 174
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
500-881 |
2.41e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 55.11 E-value: 2.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 500 EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI----ENLQEQLRDKDKQLTNLKDRVKSLQTD 575
Cdd:pfam05483 229 EEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTklqdENLKELIEKKDHLTKELEDIKMSLQRS 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 576 SSNTDTalatLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS 655
Cdd:pfam05483 309 MSTQKA----LEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITM 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 656 AGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEI--- 732
Cdd:pfam05483 385 ELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAikt 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 733 -----LKEVENEKNDKDK---KIAELERH---MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEE- 800
Cdd:pfam05483 465 seehyLKEVEDLKTELEKeklKNIELTAHcdkLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEm 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 801 -LMNALEKTRQEL----DATKARLASTqqslaEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALL--ELSA 873
Cdd:pfam05483 545 nLRDELESVREEFiqkgDEVKCKLDKS-----EENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELhqENKA 619
|
....*...
gi 1958683006 874 SKKKKTQE 881
Cdd:pfam05483 620 LKKKGSAE 627
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
331-849 |
2.46e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.18 E-value: 2.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 331 RMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKA-LQTVIEMKDTKIASLERNIRDLEDEIQML---KA 406
Cdd:pfam01576 20 RQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRArLAARKQELEEILHELESRLEEEEERSQQLqneKK 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 407 NGVLNTEDREEEIKQIEVYKSHSKFMKTKIDqlkQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAA 486
Cdd:pfam01576 100 KMQQHIQDLEEQLDEEEAARQKLQLEKVTTE---AKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 487 ILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerKINVLQKKIENLQEQLRDKDKQLTNLK 566
Cdd:pfam01576 177 SLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE-------QIAELQAQIAELRAQLAKKEEELQAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 567 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL---EEIESFRKENKDLKEKVNALQAELTEKESSL 643
Cdd:pfam01576 250 ARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRdlgEELEALKTELEDTLDTTAAQQELRSKREQEV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 644 IDLKE--------HASSLASAGLKRDSKLKSLEIAIEQKK--------------EECNKLEAQLKKAHNIEDDSRMN--- 698
Cdd:pfam01576 330 TELKKaleeetrsHEAQLQEMRQKHTQALEELTEQLEQAKrnkanlekakqaleSENAELQAELRTLQQAKQDSEHKrkk 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 699 -----PEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQN--------KKVANLK 765
Cdd:pfam01576 410 legqlQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQellqeetrQKLNLST 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 766 HNQQLEKKKNAqLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLE 845
Cdd:pfam01576 490 RLRQLEDERNS-LQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAY 568
|
....
gi 1958683006 846 EILE 849
Cdd:pfam01576 569 DKLE 572
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
701-891 |
3.24e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 53.68 E-value: 3.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 701 FAD-RLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLkhNQQLEKKK----- 774
Cdd:COG3883 13 FADpQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEA--EAEIEERReelge 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 775 -----------------------------NAQLLEEVRRREDSMVDnsqhlQIEELMNALEKTRQELDATKARLASTQQS 825
Cdd:COG3883 91 raralyrsggsvsyldvllgsesfsdfldRLSALSKIADADADLLE-----ELKADKAELEAKKAELEAKLAELEALKAE 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 826 LAEKEAHLANLRMERRKQLEEiLEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 891
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQ-LSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
381-844 |
4.29e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.46 E-value: 4.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 381 EMKDTKIASLERNIRDLEDEIQMLKA--NGVLNTED-----REEEIKQIEvyKSHSKFMKTKIDQLKQELSKK---ESEL 450
Cdd:pfam12128 279 EERQETSAELNQLLRTLDDQWKEKRDelNGELSAADaavakDRSELEALE--DQHGAFLDADIETAAADQEQLpswQSEL 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 451 LALQTKLETL---------------SNQNSDCKQHIEVLKESL-----TAKEQRAAI---LQTEVDALRLRLEEKESFLN 507
Cdd:pfam12128 357 ENLEERLKALtgkhqdvtakynrrrSKIKEQNNRDIAGIKDKLakireARDRQLAVAeddLQALESELREQLEAGKLEFN 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 508 KKTKQLQD-LTEEKGTLAGEIRDmKDMLEVKERKinvlQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATL 586
Cdd:pfam12128 437 EEEYRLKSrLGELKLRLNQATAT-PELLLQLENF----DERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQA 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 587 EEALSEKERIIERLKEQRerdDRERLEEIESFRKENKDLKEKVNALQAELTEKESSL---IDLKEHASSLASAGLKRDsk 663
Cdd:pfam12128 512 SRRLEERQSALDELELQL---FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLdpeVWDGSVGGELNLYGVKLD-- 586
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 664 LKSLEIAIEQKKEEcnKLEAQLKKAHNIEDDSRmnpefaDRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVE------ 737
Cdd:pfam12128 587 LKRIDVPEWAASEE--ELRERLDKAEEALQSAR------EKQAAAEEQLVQANGELEKASREETFARTALKNARldlrrl 658
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 738 -NEK-NDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRR--REDSMVDNSQHLQIEELMNAlektrqELD 813
Cdd:pfam12128 659 fDEKqSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEqkREARTEKQAYWQVVEGALDA------QLA 732
|
490 500 510
....*....|....*....|....*....|.
gi 1958683006 814 ATKARLASTQQSLAekeAHLANLRMERRKQL 844
Cdd:pfam12128 733 LLKAAIAARRSGAK---AELKALETWYKRDL 760
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
224-760 |
4.39e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 4.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 224 TIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELT--EENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKqtlNAR 301
Cdd:COG4913 263 RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDALREELDELEAQIRGNG---GDR 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 302 DESIKKLLEMLQskglpskslEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRsqLQPEPAKTKALQTVIE 381
Cdd:COG4913 340 LEQLEREIERLE---------RELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL--LEALEEELEALEEALA 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 382 MKDTKIASLERNIRDLEDEIQMLKANGVlNTEDREEEIKqievykshskfmktkiDQLKQELSKKESEL----------- 450
Cdd:COG4913 409 EAEAALRDLRRELRELEAEIASLERRKS-NIPARLLALR----------------DALAEALGLDEAELpfvgelievrp 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 451 ------LALQTKLETLS-----------------NQNSDcKQHIEVLKESLTAKEQRAAilQTEVDALRLRLEEKES--- 504
Cdd:COG4913 472 eeerwrGAIERVLGGFAltllvppehyaaalrwvNRLHL-RGRLVYERVRTGLPDPERP--RLDPDSLAGKLDFKPHpfr 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 505 -FLNKKTKQLQDL----------TEEKG-TLAGEIRDMKDMLEVK---------------ERKINVLQKKIENLQEQLRD 557
Cdd:COG4913 549 aWLEAELGRRFDYvcvdspeelrRHPRAiTRAGQVKGNGTRHEKDdrrrirsryvlgfdnRAKLAALEAELAELEEELAE 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 558 KDKQLTNLKDRVKSLQTDSSntdtALATLEEALsekERIIERLKEQRERDD-RERLEEIESFRKENKDLKEKVNALQAEL 636
Cdd:COG4913 629 AEERLEALEAELDALQERRE----ALQRLAEYS---WDEIDVASAEREIAElEAELERLDASSDDLAALEEQLEELEAEL 701
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 637 TEKESSLIDLKEhasslasaglkrdsKLKSLEIAIEQKKEECNKLEAQLKKAHNIEdDSRMNPEFADRLKQLDKEASYyr 716
Cdd:COG4913 702 EELEEELDELKG--------------EIGRLEKELEQAEEELDELQDRLEAAEDLA-RLELRALLEERFAAALGDAVE-- 764
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1958683006 717 decgkaqAEVDRLLEilKEVENEKNDKDKKIAELERHMKDQNKK 760
Cdd:COG4913 765 -------RELRENLE--ERIDALRARLNRAEEELERAMRAFNRE 799
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
219-836 |
7.42e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 53.54 E-value: 7.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 219 QHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKEL---FLLRKTLE-EMELRIETQ 294
Cdd:COG5022 768 LKRIKKIQVIQHGFRLRRLVDYELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIkreKKLRETEEvEFSLKAEVL 847
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 295 KQTLnARDESIKKLLEMLQSKGLPSKS---LEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH--RRSQLQPE 369
Cdd:COG5022 848 IQKF-GRSLKAKKRFSLLKKETIYLQSaqrVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSsdLIENLEFK 926
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 370 PAKTKALQTVIEMKDTKIASlERNIRDLEDEIQMLKANGVLN--TEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Cdd:COG5022 927 TELIARLKKLLNNIDLEEGP-SIEYVKLPELNKLHEVESKLKetSEEYEDLLKKSTILVREGNKANSELKNFKKELAELS 1005
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 448 SELLALQTK---LETLSNQNSDCKQHIEVLKESLTAKEQR-----------AAILQTEVDALRLRLEEKESFLNKKTKQL 513
Cdd:COG5022 1006 KQYGALQEStkqLKELPVEVAELQSASKIISSESTELSILkplqklkglllLENNQLQARYKALKLRRENSLLDDKQLYQ 1085
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 514 QDLTE--EKGTLAGEIRDMKDMLEVKERKINVL---QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA--LATL 586
Cdd:COG5022 1086 LESTEnlLKTINVKDLEVTNRNLVKPANVLQFIvaqMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLfwEANL 1165
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 587 EEALSEKERIieRLKEQRERDDRERLEEIESFRKENKDLKEKVNAL----------QAELTEKESSLIDLKEHASSLASA 656
Cdd:COG5022 1166 EALPSPPPFA--ALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALfskifsgwprGDKLKKLISEGWVPTEYSTSLKGF 1243
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 657 GLKRD--------------SKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFAD----RLKQL-DKEASYYRD 717
Cdd:COG5022 1244 NNLNKkfdtpasmsnekllSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKasslRWKSAtEVNYNSEEL 1323
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 718 ECGKAQAEVDRL---LEILKEVENEKNDKDKKIAELERHMKDQNK----KVANLKHNQQLEKKKNaQLLEEVRRREDSMV 790
Cdd:COG5022 1324 DDWCREFEISDVdeeLEELIQAVKVLQLLKDDLNKLDELLDACYSlnpaEIQNLKSRYDPADKEN-NLPKEILKKIEALL 1402
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 1958683006 791 DNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANL 836
Cdd:COG5022 1403 IKQELQLSLEGKDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL 1448
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
380-640 |
8.96e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 8.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 380 IEMKDTKIASLERNIRDLEDEIQMLKANgVLNTEDREEEIKQIEVYKSHSKFMKT---KIDQLKQELSKKE---SELLAL 453
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAE-LDALQERREALQRLAEYSWDEIDVASaerEIAELEAELERLDassDDLAAL 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 454 QTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFlnKKTKQLQDLTEEKGTLAGEiRDMKDM 533
Cdd:COG4913 691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL--ARLELRALLEERFAAALGD-AVEREL 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 534 LEVKERKINVLQKKIENLQEQLRDKdkqltnLKDRVKSLQTDSSNTDTALATLEEALSEKERII--------ERLKEQRE 605
Cdd:COG4913 768 RENLEERIDALRARLNRAEEELERA------MRAFNREWPAETADLDADLESLPEYLALLDRLEedglpeyeERFKELLN 841
|
250 260 270
....*....|....*....|....*....|....*.
gi 1958683006 606 RDDRERLEEIES-FRKENKDLKEKVNALQAELTEKE 640
Cdd:COG4913 842 ENSIEFVADLLSkLRRAIREIKERIDPLNDSLKRIP 877
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
162-651 |
9.43e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.85 E-value: 9.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 162 DLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARmsvlkeqmrvsHEENQHLQLTIQALQDELRTQRDLNHL 241
Cdd:COG4717 45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEK-----------EEEYAELQEELEELEEELEELEAELEE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 242 LQQESGN--RGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskGLPS 319
Cdd:COG4717 114 LREELEKleKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLE-----QLSL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 320 KSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQT------------VIEMKDTKI 387
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallALLGLGGSL 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 388 ASLERNIRDLEDEIQMLKANGVL----NTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE----SELLALQTKLET 459
Cdd:COG4717 269 LSLILTIAGVLFLVLGLLALLFLllarEKASLGKEAEELQALPALEELEEEELEELLAALGLPPdlspEELLELLDRIEE 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 460 LSNQNSDCKQHIEVLKESLTAKEQRAAILQTEV---DALRLRLEEKESFLNKKtKQLQDLTEEKGTLAGEIRDMKDMLEV 536
Cdd:COG4717 349 LQELLREAEELEEELQLEELEQEIAALLAEAGVedeEELRAALEQAEEYQELK-EELEELEEQLEELLGELEELLEALDE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 537 KErkinvLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAlATLEEALSEKERIIERLKEQRERDDRERL---- 612
Cdd:COG4717 428 EE-----LEEELEELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAELRELAEEWAALKLalel 501
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1958683006 613 --EEIESFRKENKD-LKEKVNALQAELTEKESSLIDLKEHAS 651
Cdd:COG4717 502 leEAREEYREERLPpVLERASEYFSRLTDGRYRLIRIDEDLS 543
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
149-553 |
1.17e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSvLKEQMRVSHEENQHLQLTIQAL 228
Cdd:TIGR02168 702 ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE-LEAEIEELEERLEEAEEELAEA 780
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 229 QDELRTqrdlnhlLQQESGNRGAEHFTIeltEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 308
Cdd:TIGR02168 781 EAEIEE-------LEAQIEQLKEELKAL---REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 309 LEMLQSKglpSKSLEDDNErtrRMAEAESQvshLEVILDQKEKENIHLREELHRRSQLqpepaktkalqtviemkDTKIA 388
Cdd:TIGR02168 851 SEDIESL---AAEIEELEE---LIEELESE---LEALLNERASLEEALALLRSELEEL-----------------SEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 389 SLERNIRDLEDEIQMLKangvlntedreEEIKQIEvykshskfmkTKIDQLKQElskkesellaLQTKLETLSNQNSDCK 468
Cdd:TIGR02168 905 ELESKRSELRRELEELR-----------EKLAQLE----------LRLEGLEVR----------IDNLQERLSEEYSLTL 953
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 469 QHIEVLKESLTAKEQRAailQTEVDALRLRL--------------EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDml 534
Cdd:TIGR02168 954 EEAEALENKIEDDEEEA---RRRLKRLENKIkelgpvnlaaieeyEELKERYDFLTAQKEDLTEAKETLEEAIEEIDR-- 1028
|
410
....*....|....*....
gi 1958683006 535 EVKERKINVLQKKIENLQE 553
Cdd:TIGR02168 1029 EARERFKDTFDQVNENFQR 1047
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
139-794 |
1.24e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 139 LRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKtfwSPELKKERVLRKEEAARMSvlkEQMRVSHEEN 218
Cdd:PTZ00121 1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK---AEEARKADELKKAEEKKKA---DEAKKAEEKK 1302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 219 QHLQLTIQAlqDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTl 298
Cdd:PTZ00121 1303 KADEAKKKA--EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK- 1379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 299 naRDESIKKLLEMLQSKGLPSKSLEDDN--ERTRRMAEAESQVSHLevildQKEKENIHLREELHRRSQ--LQPEPAKTK 374
Cdd:PTZ00121 1380 --ADAAKKKAEEKKKADEAKKKAEEDKKkaDELKKAAAAKKKADEA-----KKKAEEKKKADEAKKKAEeaKKADEAKKK 1452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 375 ALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKfmKTKIDQLKQ-ELSKKESELLAL 453
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA--KKKADEAKKaEEAKKADEAKKA 1530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 454 QTKLETLSNQNSDCKQHIEVLKEsltAKEQRAAILQTEVDALRlRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM 533
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADELKK---AEELKKAEEKKKAEEAK-KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKK 1606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 534 LEVKE-RKINVLQKKIENLQ--EQLRDKDKQLTNL--KDRVKSLQTDSSNTDTALATLEEALSEKERIiERLKEQRERDD 608
Cdd:PTZ00121 1607 MKAEEaKKAEEAKIKAEELKkaEEEKKKVEQLKKKeaEEKKKAEELKKAEEENKIKAAEEAKKAEEDK-KKAEEAKKAEE 1685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 609 RERLEEIESFRKENKdlKEKVNALQAELTEKesslidlKEHASSLASAGLKRDSKLKSLEIAIEQKK---EECNKLEAQL 685
Cdd:PTZ00121 1686 DEKKAAEALKKEAEE--AKKAEELKKKEAEE-------KKKAEELKKAEEENKIKAEEAKKEAEEDKkkaEEAKKDEEEK 1756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 686 KK-AHNIEDDSRMNPEFADRLKQLDKEASYYRDEcgKAQAEVDRLLEILK---EVENEKNDKDKKIAELERHMKDQNKKV 761
Cdd:PTZ00121 1757 KKiAHLKKEEEKKAEEIRKEKEAVIEEELDEEDE--KRRMEVDKKIKDIFdnfANIIEGGKEGNLVINDSKEMEDSAIKE 1834
|
650 660 670
....*....|....*....|....*....|...
gi 1958683006 762 ANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQ 794
Cdd:PTZ00121 1835 VADSKNMQLEEADAFEKHKFNKNNENGEDGNKE 1867
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
740-853 |
1.37e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.09 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 740 KNDKDKKIAELE----RHMKDQNKKVANLKHNQQLE-----KKKNAQLLEEVRRREDSMVDNSQHLQIEEL-----MNAL 805
Cdd:PRK12704 26 KKIAEAKIKEAEeeakRILEEAKKEAEAIKKEALLEakeeiHKLRNEFEKELRERRNELQKLEKRLLQKEEnldrkLELL 105
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1958683006 806 EKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQE 853
Cdd:PRK12704 106 EKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
415-884 |
1.91e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 52.36 E-value: 1.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 415 REEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLEtlsnQNSDCKQHIEVLKESLTAKEQRAAILQTEVDA 494
Cdd:TIGR00606 174 KFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKE----KACEIRDQITSKEAQLESSREIVKSYENELDP 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI----ENLQEQLRDKDKQLTNLKDRVK 570
Cdd:TIGR00606 250 LKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLndlyHNHQRTVREKERELVDCQRELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 571 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLE-----EIESFRKENKDLKEKVNA--LQAELTEKESSL 643
Cdd:TIGR00606 330 KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSlatrlELDGFERGPFSERQIKNFhtLVIERQEDEAKT 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 644 I-----DLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKkahNIEDDSRMNPEFADRLKQLDKEASYYRDE 718
Cdd:TIGR00606 410 AaqlcaDLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELK---FVIKELQQLEGSSDRILELDQELRKAERE 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 719 CGKAQ--AEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKK---NAQLLEEVRRREDSMVDNS 793
Cdd:TIGR00606 487 LSKAEknSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKmdkDEQIRKIKSRHSDELTSLL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 794 QHL-QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMkQEALLAAISEKDANIALLELS 872
Cdd:TIGR00606 567 GYFpNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY-EDKLFDVCGSQDEESDLERLK 645
|
490
....*....|..
gi 1958683006 873 ASKKKKTQEEVM 884
Cdd:TIGR00606 646 EEIEKSSKQRAM 657
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
264-900 |
3.05e-06 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 51.29 E-value: 3.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 264 RRLQaEHDRQAKELFLLRKTLEEMELRIETQKQTLNArdesikklLEMLQSKGlpsksleddnertrrMAEAESQVSHL- 342
Cdd:pfam07111 70 RQLQ-ELRRLEEEVRLLRETSLQQKMRLEAQAMELDA--------LAVAEKAG---------------QAEAEGLRAALa 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 343 --EVILDQKEKENIHLREELHRRSQLQPEpAKTKALQTVIEMKDTKIASLERNIRDLEDEiqmlkangvlntedREEEIK 420
Cdd:pfam07111 126 gaEMVRKNLEEGSQRELEEIQRLHQEQLS-SLTQAHEEALSSLTSKAEGLEKSLNSLETK--------------RAGEAK 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 421 QIEVYKSHSkfmktkiDQLKQELSKKESELLALQTKLETLSN----------QNSDCKQHIEVLKESLTAKEQRAAILQT 490
Cdd:pfam07111 191 QLAEAQKEA-------ELLRKQLSKTQEELEAQVTLVESLRKyvgeqvppevHSQTWELERQELLDTMQHLQEDRADLQA 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 491 EVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEI-RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQltnLKDRV 569
Cdd:pfam07111 264 TVELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFpKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQ---LRGQV 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 570 KSLQTDSSNTDTALATLEEALSEK--ERIIERLKEQRERDDRERLEEIESFRKENKDLKEKvnalqaeltekessliDLK 647
Cdd:pfam07111 341 AELQEQVTSQSQEQAILQRALQDKaaEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEE----------------QLK 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 648 EHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEddSRMNPEFAdrLKQLDKEASYYRDECGKAQAEVD 727
Cdd:pfam07111 405 FVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTIK--GLMARKVA--LAQLRQESCPPPPPAPPVDADLS 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 728 RLLEILKEvenEKNDKDkkiAELERHMKDQNKKVANLKHNQQLEKKK----NAQLLEEVRRREDSMVDNSQHLQI----- 798
Cdd:pfam07111 481 LELEQLRE---ERNRLD---AELQLSAHLIQQEVGRAREQGEAERQQlsevAQQLEQELQRAQESLASVGQQLEVarqgq 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 799 EELMNALEKTRQELDATKARLA-STQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLA-------AISEKDANIALLE 870
Cdd:pfam07111 555 QESTEEAASLRQELTQQQEIYGqALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSlrqiqhrATQEKERNQELRR 634
|
650 660 670
....*....|....*....|....*....|....
gi 1958683006 871 LSASKKK----KTQEEVMALKREKDRLVHQLKQQ 900
Cdd:pfam07111 635 LQDEARKeegqRLARRVQELERDKNLMLATLQQE 668
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
472-621 |
3.32e-06 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 51.01 E-value: 3.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 472 EVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQdlteekgtlaGEIRDMKDMLEVKERKINVLQKKIENL 551
Cdd:COG2433 384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE----------AEVEELEAELEEKDERIERLERELSEA 453
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 552 QEQLRD---KDKQLTNLKDRVKSLQTDssntdtaLATLEEALSEKERIIERLKEQRERDDRERLE---EIESFRKE 621
Cdd:COG2433 454 RSEERReirKDREISRLDREIERLERE-------LEEERERIEELKRKLERLKELWKLEHSGELVpvkVVEKFTKE 522
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
493-747 |
5.47e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 50.67 E-value: 5.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 493 DALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKK----IENLQEQLRDKDKqltnLKDR 568
Cdd:PLN02939 96 DHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQArlqaLEDLEKILTEKEA----LQGK 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 569 VKSLQTDSSNTDTALAtleeaLSEKERI-IERLKEQRERDDRERL--------------EEIESFRKENKDLKEKVNALQ 633
Cdd:PLN02939 172 INILEMRLSETDARIK-----LAAQEKIhVEILEEQLEKLRNELLirgateglcvhslsKELDVLKEENMLLKDDIQFLK 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 634 AELT------------EKESSLID--LKEHASSLASAglKRD-SKLKSLEIAIEQKKEEcnKLEAQLKKAHNIEDDSRM- 697
Cdd:PLN02939 247 AELIevaeteervfklEKERSLLDasLRELESKFIVA--QEDvSKLSPLQYDCWWEKVE--NLQDLLDRATNQVEKAALv 322
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 698 ---NPEFADRLKQLD---KEASYYRDECGKaqaeVDRLLEILKEVENEKNDKDKKI 747
Cdd:PLN02939 323 ldqNQDLRDKVDKLEaslKEANVSKFSSYK----VELLQQKLKLLEERLQASDHEI 374
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
704-861 |
7.54e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 48.38 E-value: 7.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 704 RLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKhnQQLEKKKNAQLLEEVR 783
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE--EQLGNVRNNKEYEALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 784 RREDSMVDNSQHL--QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEmKQEALLAAISE 861
Cdd:COG1579 96 KEIESLKRRISDLedEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA-EREELAAKIPP 174
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
383-677 |
8.24e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 50.04 E-value: 8.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 383 KDTKIASLERNIRDLEDEIQMLKA--NGVLNT-----EDREEEIKQIEvYKSHSKFMKTKIDQLKQELSKKESELLALQT 455
Cdd:PTZ00108 997 KEYLLGKLERELARLSNKVRFIKHviNGELVItnakkKDLVKELKKLG-YVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 456 KLETLSNQNSDC-------------KQHIEVLKESLTAKEQRAAILQ---------TEVDALRLRLEEKESFLNKKTKQL 513
Cdd:PTZ00108 1076 EDDEEELGAAVSydyllsmpiwsltKEKVEKLNAELEKKEKELEKLKnttpkdmwlEDLDKFEEALEEQEEVEEKEIAKE 1155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 514 QDLTEEKGTLAGEIRDMKDMLEVKERKIN----------VLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAL 583
Cdd:PTZ00108 1156 QRLKSKTKGKASKLRKPKLKKKEKKKKKSsadkskkasvVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKP 1235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 584 ATLEEALSEKERIIERLKEQRERDDRERLEEIESFRkenKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSK 663
Cdd:PTZ00108 1236 KKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKP---KNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKK 1312
|
330
....*....|....*
gi 1958683006 664 -LKSLEIAIEQKKEE 677
Cdd:PTZ00108 1313 rLEGSLAALKKKKKS 1327
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
317-655 |
9.83e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 49.90 E-value: 9.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 317 LPSKSLEDDNERTRrmaeaeSQVSHLEVILDQKEKENIHLREElHRRSQLQpepaktkaLQTVIEMkdtkIASLERNI-- 394
Cdd:PLN02939 86 LPQKSTSSDDDHNR------ASMQRDEAIAAIDNEQQTNSKDG-EQLSDFQ--------LEDLVGM----IQNAEKNIll 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 395 ------RDLEDEIQMLKANGVLNTE---------DREEEIKQIEVYKSHSKFMKTKIDQLKQELSKK----ESELLALQT 455
Cdd:PLN02939 147 lnqarlQALEDLEKILTEKEALQGKinilemrlsETDARIKLAAQEKIHVEILEEQLEKLRNELLIRgateGLCVHSLSK 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 456 KLETLSNQNSDCKQHIEVLKESLtakeqraaILQTEVDALRLRLEEKESFLNKKTKQLqdltEEKGTLAGEirdmkDMLE 535
Cdd:PLN02939 227 ELDVLKEENMLLKDDIQFLKAEL--------IEVAETEERVFKLEKERSLLDASLREL----ESKFIVAQE-----DVSK 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 536 VKERKINVLQKKIENLQEQLRDKDKQLTN----------LKDRVKSLQTDSSNTDTALATLE--EALSEKeriIERLKEQ 603
Cdd:PLN02939 290 LSPLQYDCWWEKVENLQDLLDRATNQVEKaalvldqnqdLRDKVDKLEASLKEANVSKFSSYkvELLQQK---LKLLEER 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1958683006 604 RERDDRERLEEIESFRKENKDLKEKVNALQAElTEKESslidLKEHASSLAS 655
Cdd:PLN02939 367 LQASDHEIHSYIQLYQESIKEFQDTLSKLKEE-SKKRS----LEHPADDMPS 413
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
268-684 |
1.53e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 268 AEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSK------SLEDDNERTRRMAEAESQVSH 341
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQElealeaELAELPERLEELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 342 LEVILDQKEKENIHLREELhRRSQLQPEPAKTKALQTVIEmkdtKIASLERNIRDLEDEIQMLKANGvlntEDREEEIKQ 421
Cdd:COG4717 161 LEEELEELEAELAELQEEL-EELLEQLSLATEEELQDLAE----ELEELQQRLAELEEELEEAQEEL----EELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 422 IEVYKSHSKfMKTKIDQLKQeLSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 501
Cdd:COG4717 232 LENELEAAA-LEERLKEARL-LLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 502 KESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdkQLTNLKDRVKSLQTDSSNTDT 581
Cdd:COG4717 310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ----LEELEQEIAALLAEAGVEDEE 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 582 ALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD-LKEKVNALQAELTEKESSLIDLKEHASSLAS--AGL 658
Cdd:COG4717 386 ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEeLEEELEELEEELEELEEELEELREELAELEAelEQL 465
|
410 420
....*....|....*....|....*.
gi 1958683006 659 KRDSKLKSLEIAIEQKKEECNKLEAQ 684
Cdd:COG4717 466 EEDGELAELLQELEELKAELRELAEE 491
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
281-616 |
1.68e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.91 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 281 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQS---KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLR 357
Cdd:PRK03918 400 KEEIEEEISKITARIGELKKEIKELKKAIEELKKakgKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 358 EELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQML-KANGVLNT-----EDREEEIKQIEVYKSHSK 430
Cdd:PRK03918 480 KELRElEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYeKLKEKLIKlkgeiKSLKKELEKLEELKKKLA 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 431 FMKTKIDQLKQELSKKESELLALQTKL-----ETLSNQNSDCKQHIEVL--KESLTAKEQRAAILQTEVDALRLRLEEKE 503
Cdd:PRK03918 560 ELEKKLDELEEELAELLKELEELGFESveeleERLKELEPFYNEYLELKdaEKELEREEKELKKLEEELDKAFEELAETE 639
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 504 SFLNKKTKQLQDLteEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLqtdsSNTDTAL 583
Cdd:PRK03918 640 KRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER----EKAKKEL 713
|
330 340 350
....*....|....*....|....*....|...
gi 1958683006 584 ATLEEALSEKERIIERLKEQRERDDRERLEEIE 616
Cdd:PRK03918 714 EKLEKALERVEELREKVKKYKALLKERALSKVG 746
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
415-907 |
2.22e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 48.63 E-value: 2.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 415 REEEIKQIEVYKSHSKFMKTKIDQLKQELSKkESELLALQTKLET------------LSNQNSDCKQHIEVLKESLTAKE 482
Cdd:pfam01576 10 KEEELQKVKERQQKAESELKELEKKHQQLCE-EKNALQEQLQAETelcaeaeemrarLAARKQELEEILHELESRLEEEE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 483 QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQL 562
Cdd:pfam01576 89 ERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 563 TNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRerleeiesfrkENKDLKEKVNALQAELTEKESS 642
Cdd:pfam01576 169 AEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEG-----------ESTDLQEQIAELQAQIAELRAQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 643 LidlkehasslasaglkrDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDdsrmnpEFADRLKQLDKEASYYrdecGKA 722
Cdd:pfam01576 238 L-----------------AKKEEELQAALARLEEETAQKNNALKKIRELEA------QISELQEDLESERAAR----NKA 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 723 QAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVD--NSQHLQIEE 800
Cdd:pfam01576 291 EKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEelTEQLEQAKR 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 801 LMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEIL----------EMKQEALLAAISEKDANIALLE 870
Cdd:pfam01576 371 NKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQarlseserqrAELAEKLSKLQSELESVSSLLN 450
|
490 500 510
....*....|....*....|....*....|....*..
gi 1958683006 871 LSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 907
Cdd:pfam01576 451 EAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNL 487
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
371-599 |
2.59e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.47 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 371 AKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKA-NGVLNTEDREEEIKQievykshskfmktKIDQLKQELSKKESE 449
Cdd:COG3206 168 LRREEARKALEFLEEQLPELRKELEEAEAALEEFRQkNGLVDLSEEAKLLLQ-------------QLSELESQLAEARAE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 450 LLALQTKLETLSNQNSDCKQHIEVLKES--LTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEkgtLAGEI 527
Cdd:COG3206 235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ---LQQEA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 528 RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT----DTALATLEEALSEKE------RII 597
Cdd:COG3206 312 QRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVArelyESLLQRLEEARLAEAltvgnvRVI 391
|
..
gi 1958683006 598 ER 599
Cdd:COG3206 392 DP 393
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
420-725 |
2.65e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.20 E-value: 2.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 420 KQIEVYKSHSKFMKTKIDQLKQELSKKESELlALQTKLEtlsnqNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 499
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREV-ERRRKLE-----EAEKARQAEMDRQAAIYAEQERMAMERERELERIRQ 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 500 EEKEsflnkktKQLQDLTEEKgtLAGEIRDMKDMlevkERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT 579
Cdd:pfam17380 356 EERK-------RELERIRQEE--IAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 580 DTALATLEEALS------------EKERIieRLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLI--D 645
Cdd:pfam17380 423 EQIRAEQEEARQrevrrleeerarEMERV--RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILekE 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 646 LKEHASSLASAGLKRDSKLKSLE-----IAIEQKK---EECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRD 717
Cdd:pfam17380 501 LEERKQAMIEEERKRKLLEKEMEerqkaIYEEERRreaEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580
|
330
....*....|
gi 1958683006 718 --ECGKAQAE 725
Cdd:pfam17380 581 ivESEKARAE 590
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
384-558 |
2.79e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.84 E-value: 2.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 384 DTKIASLERNIRDLEDEIQMLKAngvlNTEDREEEIKQIevykshskfmKTKIDQLKQELSKKESELLALQTKLETLSNQ 463
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELED----ELAALEARLEAA----------KTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 464 nsdckqhievLKESLTAKEQRAaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINV 543
Cdd:COG1579 82 ----------LGNVRNNKEYEA--LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDE 149
|
170
....*....|....*
gi 1958683006 544 LQKKIENLQEQLRDK 558
Cdd:COG1579 150 ELAELEAELEELEAE 164
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
139-889 |
3.39e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.12 E-value: 3.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 139 LRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDsKLGSSMNsiktfwspELKKERVLRKEEAARMSVLKEQMRvsheEN 218
Cdd:TIGR00606 191 LRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRD-QITSKEA--------QLESSREIVKSYENELDPLKNRLK----EI 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 219 QHLQLTIQALQDELRTQRDLNhlLQQESGNRGAEHFTIEL---TEENFRRLQAEHDRQAKElfllrKTLEEMELRIETQK 295
Cdd:TIGR00606 258 EHNLSKIMKLDNEIKALKSRK--KQMEKDNSELELKMEKVfqgTDEQLNDLYHNHQRTVRE-----KERELVDCQRELEK 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 296 QTLNARDESIKKLlEMLQSKGLPSKSLEDDNERTR-RMAEAESQVSHLEV-ILDQKEKENIHLREELHRRSQLQPEPAKT 373
Cdd:TIGR00606 331 LNKERRLLNQEKT-ELLVEQGRLQLQADRHQEHIRaRDSLIQSLATRLELdGFERGPFSERQIKNFHTLVIERQEDEAKT 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 374 KAlQTVIEMKDtKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKID---QLKQELSKKESEL 450
Cdd:TIGR00606 410 AA-QLCADLQS-KERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDrilELDQELRKAEREL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 451 LALQtkletlSNQNSDCKqhievLKESLTAKEQRAAILQTevdalRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEI 527
Cdd:TIGR00606 488 SKAE------KNSLTETL-----KKEVKSLQNEKADLDRK-----LRKLDQEMEQLNHHTttrTQMEMLTKDKMDKDEQI 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 528 RDMKDMLEVKERKI-------NVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSE-KERIIER 599
Cdd:TIGR00606 552 RKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSyEDKLFDV 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 600 LKEQRERDDRERL-EEIESFRKENKDLKEKVNALQA---ELTEKESSLI-----------DLKEHASSLASAGLKRDSKL 664
Cdd:TIGR00606 632 CGSQDEESDLERLkEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCpvcqrvfqteaELQEFISDLQSKLRLAPDKL 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 665 KSLEIAIEQKKEECNKLEAQLKKAHNIED-DSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDK 743
Cdd:TIGR00606 712 KSTESELKKKEKRRDEMLGLAPGRQSIIDlKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDV 791
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 744 dKKIAELERHMKDQNKKVAnlkhnQQLEKKKNAQLLEEVRRREDSMVDNSQHL-QIEELMNALEKTRQELDATKARLAST 822
Cdd:TIGR00606 792 -TIMERFQMELKDVERKIA-----QQAAKLQGSDLDRTVQQVNQEKQEKQHELdTVVSKIELNRKLIQDQQEQIQHLKSK 865
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 823 QQSLAEKEAHLANlRMERRKQLEEILEMKQEALLAAISE-KDANIALLELSASKKKKTQEEVMALKRE 889
Cdd:TIGR00606 866 TNELKSEKLQIGT-NLQRRQQFEEQLVELSTEVQSLIREiKDAKEQDSPLETFLEKDQQEKEELISSK 932
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
368-688 |
3.80e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 47.64 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 368 PEPAKTKALQTVIEMKDTKIASLerNIRDLEDEIQMLKANGVLntEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 447
Cdd:COG5185 198 AEPSGTVNSIKESETGNLGSEST--LLEKAKEIINIEEALKGF--QDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGEN 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 448 SEllalqtKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQT--EVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 525
Cdd:COG5185 274 AE------SSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKAteSLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQ 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 526 EIRDMKDMLEV--KERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSN-TDTALATLEEALSEKERIIERLKE 602
Cdd:COG5185 348 GQESLTENLEAikEEIENIVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGyAQEILATLEDTLKAADRQIEELQR 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 603 QRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSliDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLE 682
Cdd:COG5185 428 QIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEE--AYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLR 505
|
....*.
gi 1958683006 683 AQLKKA 688
Cdd:COG5185 506 AKLERQ 511
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
384-632 |
4.87e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 47.59 E-value: 4.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 384 DTKIASLERNIRDLEDEIQMLKangvlNTEDREEEiKQIEVYKSHSKFMKTKIDQLKqELSKKESELLALQTKLETLSNQ 463
Cdd:PRK01156 482 EEKIREIEIEVKDIDEKIVDLK-----KRKEYLES-EEINKSINEYNKIESARADLE-DIKIKINELKDKHDKYEEIKNR 554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 464 NSDCkqHIEVLK----ESLTAKEQRAAIlqtEVDALRLRLEEKesflnkkTKQLQDLTEEKGTLAGEIRDMK-------- 531
Cdd:PRK01156 555 YKSL--KLEDLDskrtSWLNALAVISLI---DIETNRSRSNEI-------KKQLNDLESRLQEIEIGFPDDKsyidksir 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 532 -------------DMLEVKERKINVLQKKIENLQEQLRDKD---KQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKER 595
Cdd:PRK01156 623 eieneannlnnkyNEIQENKILIEKLRGKIDNYKKQIAEIDsiiPDLKEITSRINDIEDNLKKSRKALDDAKANRARLES 702
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1958683006 596 IIERLK------EQRERDDRERLEEIESFRKENKDLKEKVNAL 632
Cdd:PRK01156 703 TIEILRtrinelSDRINDINETLESMKKIKKAIGDLKRLREAF 745
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
432-734 |
5.65e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.82 E-value: 5.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 432 MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511
Cdd:COG4372 43 LQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRV------KSLQTDSSNTDTALAT 585
Cdd:COG4372 123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaeqaldELLKEANRNAEKEEEL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 586 LEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLK 665
Cdd:COG4372 203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAA 282
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958683006 666 SLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILK 734
Cdd:COG4372 283 LELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLL 351
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
474-685 |
7.59e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 7.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 474 LKESLTAKEQRAAILQTEVDALRLRLEEKEsflnkktKQLQDLTEEKGTLAGEirdmkdmlevkeRKINVLQKKIENLQE 553
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAE-------AALEEFRQKNGLVDLS------------EEAKLLLQQLSELES 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 554 QLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAlsekeRIIERLKEQRERDDRERLEEIESFRKEN---KDLKEKVN 630
Cdd:COG3206 227 QLAEARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIA 301
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 631 ALQAEL-TEKESSLIDLKEHASSLASaglkRDSKLKSLEIAIEQKKEECNKLEAQL 685
Cdd:COG3206 302 ALRAQLqQEAQRILASLEAELEALQA----REASLQAQLAQLEARLAELPELEAEL 353
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
582-763 |
7.75e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 7.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 582 ALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfRKENKdLKEKVNALqaeltEKESSLIDlkehasslasaglKRD 661
Cdd:PRK12704 51 AEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQ--KLEKR-LLQKEENL-----DRKLELLE-------------KRE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 662 SKLKSLEIAIEQKKEECNKLEAQLKKAHnieddsrmnpefADRLKQLDKEASYYRDEcgkAQAevdrllEILKEVENE-K 740
Cdd:PRK12704 110 EELEKKEKELEQKQQELEKKEEELEELI------------EEQLQELERISGLTAEE---AKE------ILLEKVEEEaR 168
|
170 180
....*....|....*....|...
gi 1958683006 741 NDKDKKIAELERHMKDQNKKVAN 763
Cdd:PRK12704 169 HEAAVLIKEIEEEAKEEADKKAK 191
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
439-573 |
7.91e-05 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 46.11 E-value: 7.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 439 LKQELSKKESELLALQTKLETLSNQnsdckqhievlkesLTAKEQRAAILQTEVDALRLRLEEKES-------FLNKKTK 511
Cdd:PRK09039 44 LSREISGKDSALDRLNSQIAELADL--------------LSLERQGNQDLQDSVANLRASLSAAEAersrlqaLLAELAG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL------------RDKDKQL----------TNLKDRV 569
Cdd:PRK09039 110 AGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLaaleaaldasekRDRESQAkiadlgrrlnVALAQRV 189
|
....
gi 1958683006 570 KSLQ 573
Cdd:PRK09039 190 QELN 193
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
496-847 |
1.20e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 46.10 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 496 RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtD 575
Cdd:COG5185 162 KDIFGKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQ-D 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 576 SSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS 655
Cdd:COG5185 241 PESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAA 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 656 AGLKRD--SKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASyyrdecgKAQAEVDRL-LEI 732
Cdd:COG5185 321 AEAEQEleESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSSEELD-------SFKDTIESTkESL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 733 LKEVENEKNDKDKKIAELERHMKDQNKKVANL-----KHNQQLE--KKKNAQLLEEVRRREDSMVDNSQHLQIEELMNAL 805
Cdd:COG5185 394 DEIPQNQRGYAQEILATLEDTLKAADRQIEELqrqieQATSSNEevSKLLNELISELNKVMREADEESQSRLEEAYDEIN 473
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1958683006 806 EKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEI 847
Cdd:COG5185 474 RSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGV 515
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
344-595 |
1.28e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 46.07 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 344 VILDQKEKENIhlrEELHRRSQLQPEPAKTkalqtviEMKDTKIASLERNIRDLEDEIQMLKAngVLNTEDREEEIKQIE 423
Cdd:PRK05771 12 VTLKSYKDEVL---EALHELGVVHIEDLKE-------ELSNERLRKLRSLLTKLSEALDKLRS--YLPKLNPLREEKKKV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 424 VYKSHSKFmktkIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLK--ESLTAKEQRA-----------AILQT 490
Cdd:PRK05771 80 SVKSLEEL----IKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFDLDLSLLlgfkyvsvfvgTVPED 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 491 EVDALRLRLEEKESFLNKKTKQ-----LQDLTEEKGTLAGEIRDM-------------KDMLEVKERKINVLQKKIENLQ 552
Cdd:PRK05771 156 KLEELKLESDVENVEYISTDKGyvyvvVVVLKELSDEVEEELKKLgferleleeegtpSELIREIKEELEEIEKERESLL 235
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1958683006 553 EQLRDKDKQLTNLKdrvkslqtdssntdtaLATLEEALSEKER 595
Cdd:PRK05771 236 EELKELAKKYLEEL----------------LALYEYLEIELER 262
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
586-893 |
1.34e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 45.66 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 586 LEEALSEKE---RIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasslasaglkrds 662
Cdd:pfam07888 36 LEECLQERAellQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEE-------------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 663 KLKSLEIAIEQKKEECNKL----EAQLKKAHNIEDDSRMNPEfadrlKQLDKEAsyyrdECGKAQAEVDRLLEILKEVEN 738
Cdd:pfam07888 102 KYKELSASSEELSEEKDALlaqrAAHEARIRELEEDIKTLTQ-----RVLERET-----ELERMKERAKKAGAQRKEEEA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 739 EKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMvdNSQHLQIEELmnalEKTRQELDATKAR 818
Cdd:pfam07888 172 ERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKL--TTAHRKEAEN----EALLEELRSLQER 245
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 819 LASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRL 893
Cdd:pfam07888 246 LNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRI 320
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
610-870 |
1.51e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 1.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 610 ERLEEIESFRKENKDLKEKVNALQAELT---EKESSLIDL----------KEHASSLASAGLKRDSKLKSLEIA------ 670
Cdd:COG3206 101 DKLNLDEDPLGEEASREAAIERLRKNLTvepVKGSNVIEIsytspdpelaAAVANALAEAYLEQNLELRREEARkalefl 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 671 ---IEQKKEECNKLEAQL---KKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILK---------- 734
Cdd:COG3206 181 eeqLPELRKELEEAEAALeefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGsgpdalpell 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 735 ------EVENEKNDKDKKIAELERHMKDQNKKVANLKhnQQLEKKKnAQLLEEVRRREDSmvdnsqhlqIEELMNALEKT 808
Cdd:COG3206 261 qspviqQLRAQLAELEAELAELSARYTPNHPDVIALR--AQIAALR-AQLQQEAQRILAS---------LEAELEALQAR 328
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 809 RQELDATKARLASTQQSLAEKEAHLANLRMER---RKQLEEILEMKQEALLAAiSEKDANIALLE 870
Cdd:COG3206 329 EASLQAQLAQLEARLAELPELEAELRRLEREVevaRELYESLLQRLEEARLAE-ALTVGNVRVID 392
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
416-592 |
1.71e-04 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 45.05 E-value: 1.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 416 EEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD--CKQHIEVLKESLtaKEQRAAILQtevd 493
Cdd:cd22656 124 DDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDLLTDEGGaiARKEIKDLQKEL--EKLNEEYAA---- 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 494 ALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKkienLQEQLRDKDKQLTNLKDRVKSLQ 573
Cdd:cd22656 198 KLKAKIDELKALIADDEAKLAAALRLIADLTAADTDLDNLLALIGPAIPALEK----LQGAWQAIATDLDSLKDLLEDDI 273
|
170
....*....|....*....
gi 1958683006 574 TDSSNTDTALATLEEALSE 592
Cdd:cd22656 274 SKIPAAILAKLELEKAIEK 292
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
664-901 |
1.73e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 664 LKSLEIAIEQKKEECNKLEAQLKKAHNIEddsrmnpEFADRLKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDK 743
Cdd:TIGR02168 188 LDRLEDILNELERQLKSLERQAEKAERYK-------ELKAELRELELALLVLRLE--ELREELEELQEELKEAEEELEEL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 744 DKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREdsmvdnsqhLQIEELMNALEKTRQELDATKARLASTQ 823
Cdd:TIGR02168 259 TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE---------QQKQILRERLANLERQLEELEAQLEELE 329
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 824 QSLAEKEAHLAnlrmerrkQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQT 901
Cdd:TIGR02168 330 SKLDELAEELA--------ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
244-621 |
1.97e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.73 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 244 QESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNardesIKKLLEMLQSKGLPSKSLE 323
Cdd:pfam02463 644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQL-----EIKKKEQREKEELKKLKLE 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 324 DDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL-HRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQ 402
Cdd:pfam02463 719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSrLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 403 MLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKE 482
Cdd:pfam02463 799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEE 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 483 QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQL 562
Cdd:pfam02463 879 LEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 563 TNLKDRVKSLQTDSSNTD----TALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKE 621
Cdd:pfam02463 959 EERNKRLLLAKEELGKVNlmaiEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-383 |
2.09e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEaARMSVLKEQMRVSHEENQHLQLTIQAL 228
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE-QELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 229 QDELRTQ----------RDLNHLLQQESGNRGAEHFTIelteenFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTL 298
Cdd:COG4942 103 KEELAELlralyrlgrqPPLALLLSPEDFLDAVRRLQY------LKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 299 NARDESIKKLLEMLQSkglpsksleDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQT 378
Cdd:COG4942 177 EALLAELEEERAALEA---------LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
....*
gi 1958683006 379 VIEMK 383
Cdd:COG4942 248 FAALK 252
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
390-619 |
2.31e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.89 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 390 LERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQ 469
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 470 HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIE 549
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958683006 550 NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERL--KEQRERDDRERLEEIESFR 619
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLnaSERKVEGLGEELSSMAAQR 267
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
411-638 |
2.38e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 411 NTEDREEEIKQIevykshSKFMKTKIDQLKQELSKKESELLALQTKLETLSnqnsdckqhievLKESLTAKEQRAAILQT 490
Cdd:COG3206 165 NLELRREEARKA------LEFLEEQLPELRKELEEAEAALEEFRQKNGLVD------------LSEEAKLLLQQLSELES 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 491 EVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRdmkdmlevkerkINVLQKKIENLQEQLRDKDKQLTNLKDRVK 570
Cdd:COG3206 227 QLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV------------IQQLRAQLAELEAELAELSARYTPNHPDVI 294
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 571 SLQtdssntdtalATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKV---NALQAELTE 638
Cdd:COG3206 295 ALR----------AQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLaelPELEAELRR 355
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
256-403 |
2.66e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.77 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 256 IELTEENFRrLQAEHDRQAKELfllRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglpsksleddnertrrmaea 335
Cdd:PRK12704 60 LEAKEEIHK-LRNEFEKELRER---RNELQKLEKRLLQKEENLDRKLELLEKREEELEKK-------------------- 115
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958683006 336 ESQVSHLEVILDQKEKE--NIH--LREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLernIRDLEDEIQM 403
Cdd:PRK12704 116 EKELEQKQQELEKKEEEleELIeeQLQELERISGLTAEEAKEILLEKVEEEARHEAAVL---IKEIEEEAKE 184
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
372-594 |
2.88e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.44 E-value: 2.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 372 KTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANgvlnTEDREEEIKQIEvykshskfmkTKIDQLKQELSKKESELL 451
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE----YNELQAELEALQ----------AEIDKLQAEIAEAEAEIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 452 ALQTKLETL---SNQNSDCKQHIEVLKESLTAKE--QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 526
Cdd:COG3883 83 ERREELGERaraLYRSGGSVSYLDVLLGSESFSDflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 527 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKE 594
Cdd:COG3883 163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
417-845 |
3.13e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 45.21 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 417 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLT-------AKEQRAAILQ 489
Cdd:PTZ00440 519 NNFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDhikdiisLNDEIDNIIQ 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 490 TEVDALRLRLEEKESFLNKKTKQLQDLTE-----EKGTLAGEIRDMKDMLEVKE---------RKINVLQKKIENLQEQL 555
Cdd:PTZ00440 599 QIEELINEALFNKEKFINEKNDLQEKVKYilnkfYKGDLQELLDELSHFLDDHKylyheakskEDLQTLLNTSKNEYEKL 678
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 556 rdKDKQLTNLKDRVKSLQTDSSNtdtaLATLEEALSEK-------------ERIIERLKEQRERDDrERLEEIESFRKEN 622
Cdd:PTZ00440 679 --EFMKSDNIDNIIKNLKKELQN----LLSLKENIIKKqlnnieqdisnslNQYTIKYNDLKSSIE-EYKEEEEKLEVYK 751
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 623 KDLKEKVNALQAELTEKESSLIDLK-------EHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKahnIEDDS 695
Cdd:PTZ00440 752 HQIINRKNEFILHLYENDKDLPDGKntyeeflQYKDTILNKENKISNDINILKENKKNNQDLLNSYNILIQK---LEAHT 828
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 696 RMNPEfadRLKQLDKEASYYRDECGkaqaevdrlleiLKEVENEKNDKDKKIAELERHMKDQNKKVANLK--HNQQLEKK 773
Cdd:PTZ00440 829 EKNDE---ELKQLLQKFPTEDENLN------------LKELEKEFNENNQIVDNIIKDIENMNKNINIIKtlNIAINRSN 893
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 774 KNAQLLEEVRRREDSMVDN-SQHLQIEELMNALEKTRQE--LDATKARLASTQQSLAekEAHLANLRMERRKQLE 845
Cdd:PTZ00440 894 SNKQLVEHLLNNKIDLKNKlEQHMKIINTDNIIQKNEKLnlLNNLNKEKEKIEKQLS--DTKINNLKMQIEKTLE 966
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
432-597 |
3.27e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 44.69 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 432 MKTKIDQLKQELSKKESELLALQTKLETLSnqnsdckqhievlKESLTAKEQRAAILQTEVDALRLRLEEKEsflnkktk 511
Cdd:COG0542 402 VRMEIDSKPEELDELERRLEQLEIEKEALK-------------KEQDEASFERLAELRDELAELEEELEALK-------- 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 512 qlQDLTEEKgTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR--------------VKSLQTDSS 577
Cdd:COG0542 461 --ARWEAEK-ELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVTEediaevvsrwtgipVGKLLEGER 537
|
170 180
....*....|....*....|
gi 1958683006 578 NTdtaLATLEEALseKERII 597
Cdd:COG0542 538 EK---LLNLEEEL--HERVI 552
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
437-739 |
3.57e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.12 E-value: 3.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 437 DQLKQELSKKESELLALQTKLETL----SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Cdd:COG4372 2 DRLGEKVGKARLSLFGLRPKTGILiaalSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 513 LQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSE 592
Cdd:COG4372 82 LEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLES 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 593 KERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIE 672
Cdd:COG4372 162 LQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDA 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958683006 673 QKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENE 739
Cdd:COG4372 242 LELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALS 308
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
465-685 |
4.10e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 44.52 E-value: 4.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 465 SDCKQHIEVLKESLTAKEQRAAILQTevdalrlrLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMlevkerkinvl 544
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQD--------LEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQA----------- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 545 QKKIENLQEQLRDKDKQlTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE------RLEEIESF 618
Cdd:PRK11281 100 QAELEALKDDNDEETRE-TLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAAlyansqRLQQIRNL 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 619 RKENKDLKEKVNALQAELTEKESSLIDLKehaSSLASAGLKRDSKLKSLEIAI-EQKKEECNKLEAQL 685
Cdd:PRK11281 179 LKGGKVGGKALRPSQRVLLQAEQALLNAQ---NDLQRKSLEGNTQLQDLLQKQrDYLTARIQRLEHQL 243
|
|
| WEMBL |
pfam05701 |
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ... |
426-858 |
4.57e-04 |
|
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".
Pssm-ID: 461718 [Multi-domain] Cd Length: 562 Bit Score: 44.25 E-value: 4.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 426 KSHSKFMKTKIDQLKQELSKKESelLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESF 505
Cdd:pfam05701 97 KQDSELAKLRVEEMEQGIADEAS--VAAKAQLEVAKARHAAAVAELKSVKEELESLRKEYASLVSERDIAIKRAEEAVSA 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 506 LNKKTKQLQDLTEEKGTLAGEIRDMKDM-LEVKERKINV----------LQKKIENLQEQLRDKDKQLTNLKDRVKSLQT 574
Cdd:pfam05701 175 SKEIEKTVEELTIELIATKESLESAHAAhLEAEEHRIGAalareqdklnWEKELKQAEEELQRLNQQLLSAKDLKSKLET 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 575 DSS---NTDTALATLEEALSEKERIIERLKEQRERD-------DRERLEE----IESFRKENKDLKEKVNALQAELTEKE 640
Cdd:pfam05701 255 ASAlllDLKAELAAYMESKLKEEADGEGNEKKTSTSiqaalasAKKELEEvkanIEKAKDEVNCLRVAAASLRSELEKEK 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 641 SSLIDLK--EHASSLASAGLKRDSKLKSLEIAIEQKK-----EECNKLEAQLKKAHNIEDDSRMNPEFADrlkqldKEAS 713
Cdd:pfam05701 335 AELASLRqrEGMASIAVSSLEAELNRTKSEIALVQAKekearEKMVELPKQLQQAAQEAEEAKSLAQAAR------EELR 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 714 YYRDECGKAQAEVD----RLLEILKEVENEKndKDKKIAelerhmkdqnkkVANLKHNQQLEKKKNAQLLEEVRRredsm 789
Cdd:pfam05701 409 KAKEEAEQAKAAAStvesRLEAVLKEIEAAK--ASEKLA------------LAAIKALQESESSAESTNQEDSPR----- 469
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 790 vdnSQHLQIEELMNALEKTRQELDATKARLA-STQQSLAEKEAHLANLrmERRKQLEEILEMKQEALLAA 858
Cdd:pfam05701 470 ---GVTLSLEEYYELSKRAHEAEELANKRVAeAVSQIEEAKESELRSL--EKLEEVNREMEERKEALKIA 534
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
614-831 |
4.80e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.67 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 614 EIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKK--AHNI 691
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 692 EDDSRMNP-----------EFADRLKQLDKEASYYRDecgkaqaevdrlleILKEVENEKNDKDKKIAELERHMKDQNKK 760
Cdd:COG3883 97 RSGGSVSYldvllgsesfsDFLDRLSALSKIADADAD--------------LLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 761 VANLKhnqqlEKKKNAQlleevrrredsmvdnSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEA 831
Cdd:COG3883 163 KAELE-----AAKAELE---------------AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213
|
|
| CagA_N |
pfam18971 |
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ... |
495-783 |
5.09e-04 |
|
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.
Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 44.38 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDM-KDMLEVKER-KINVLQKKIENLQEQLRDKDkqltNLKDRV-KS 571
Cdd:pfam18971 561 LENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFnKAVAEAKSTgNYDEVKKAQKDLEKSLRKRE----HLEKEVeKK 636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 572 LQTDSSNTDTALATlEEALSEKERIIERLKEQRERD-------------DRERLEEIESFRKENKDLKEKV----NALQA 634
Cdd:pfam18971 637 LESKSGNKNKMEAK-AQANSQKDEIFALINKEANRDaraiaytqnlkgiKRELSDKLEKISKDLKDFSKSFdefkNGKNK 715
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 635 ELTEKESSLIDLKehaSSLASAGLKRD--SKLKSLEIAIEQKKEECNKLEAQLKKA----HNIEDDSRMNPEFADRLKQL 708
Cdd:pfam18971 716 DFSKAEETLKALK---GSVKDLGINPEwiSKVENLNAALNEFKNGKNKDFSKVTQAksdlENSVKDVIINQKVTDKVDNL 792
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 709 DKEASyyrdeCGKAQAEVDRLLEILKEVENEKNDKdkkiaelerhMKDQNKKvanlkhNQQLEKKKNAQLLEEVR 783
Cdd:pfam18971 793 NQAVS-----VAKAMGDFSRVEQVLADLKNFSKEQ----------LAQQAQK------NEDFNTGKNSELYQSVK 846
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
149-614 |
5.61e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.16 E-value: 5.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQAL 228
Cdd:COG1196 348 EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 229 QDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQA---EHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:COG1196 428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAElleEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 306 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENI--------HLREELHRRSQLQP-------EP 370
Cdd:COG1196 508 EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDevaaaaieYLKAAKAGRATFLPldkirarAA 587
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 371 AKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQI----EVYKSHSKFMKTKIDQLKQELSKK 446
Cdd:COG1196 588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAvtlaGRLREVTLEGEGGSAGGSLTGGSR 667
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 447 ESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 526
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 527 IRDMKDMLEVKERKINVLQKKIENLQEQLRDK-------DKQLTNLKDRVKSLQTDssntdtaLATLEEALSEKERIIER 599
Cdd:COG1196 748 LEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEYEELEERYDFLSEQ-------REDLEEARETLEEAIEE 820
|
490
....*....|....*
gi 1958683006 600 LKEQRerddRERLEE 614
Cdd:COG1196 821 IDRET----RERFLE 831
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
671-882 |
5.82e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 5.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 671 IEQKKEEcnkleaqlkKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKA---QAEVDRLLEILKEVENEKNDKDK-- 745
Cdd:pfam17380 301 LRQEKEE---------KAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmerERELERIRQEERKRELERIRQEEia 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 746 ----KIAELERHMKDQNKKvaNLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKAR-LA 820
Cdd:pfam17380 372 meisRMRELERLQMERQQK--NERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAReME 449
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 821 STQQSLAEKEAHLANLRMERRKQLEEILEM-KQEALLAAISEKDANIALLELSASKKKKTQEE 882
Cdd:pfam17380 450 RVRLEEQERQQQVERLRQQEEERKRKKLELeKEKRDRKRAEEQRRKILEKELEERKQAMIEEE 512
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
280-606 |
6.41e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 6.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 280 LRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLpsksleDDNERTRRMAEAESQVSHLEVILDQK-------EKE 352
Cdd:pfam01576 220 LQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETA------QKNNALKKIRELEAQISELQEDLESEraarnkaEKQ 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 353 NIHLREELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNI----RDLEDEIQMLKANGVLNTEDREEEIKQievyks 427
Cdd:pfam01576 294 RRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKKALeeetRSHEAQLQEMRQKHTQALEELTEQLEQ------ 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 428 hSKFMKTKIDQLKQELskkESELLALQTKLETLSNQNSDC---KQHIEVLKESLTAK-----------EQRAAILQTEVD 493
Cdd:pfam01576 368 -AKRNKANLEKAKQAL---ESENAELQAELRTLQQAKQDSehkRKKLEGQLQELQARlseserqraelAEKLSKLQSELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 494 ALRLRLEEKESFLNKKTK--------------QLQDLTEEKGTLAGEIRDMKD-------MLEVKERKINVLQKKIENLQ 552
Cdd:pfam01576 444 SVSSLLNEAEGKNIKLSKdvsslesqlqdtqeLLQEETRQKLNLSTRLRQLEDernslqeQLEEEEEAKRNVERQLSTLQ 523
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1958683006 553 EQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER 606
Cdd:pfam01576 524 AQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNR 577
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
587-712 |
6.88e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.69 E-value: 6.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 587 EEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL-------- 658
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERreirkdre 466
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958683006 659 --KRDSKLKSLEIAIEQKKEECNKLE---AQLKKAHNIEDDSRMNPefADRLKQLDKEA 712
Cdd:COG2433 467 isRLDREIERLERELEEERERIEELKrklERLKELWKLEHSGELVP--VKVVEKFTKEA 523
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
538-882 |
7.88e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 7.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 538 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRErddrERLEEIES 617
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA----QAQEELES 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 618 FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRM 697
Cdd:COG4372 106 LQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQAL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 698 NPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQ 777
Cdd:COG4372 186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELEL 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 778 LLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLA 857
Cdd:COG4372 266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQL 345
|
330 340
....*....|....*....|....*
gi 1958683006 858 AISEKDANIALLELSASKKKKTQEE 882
Cdd:COG4372 346 LLVGLLDNDVLELLSKGAEAGVADG 370
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
230-639 |
8.38e-04 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 43.13 E-value: 8.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 230 DELRTQRD----LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 305
Cdd:pfam19220 20 EDLRSLKAdfsqLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 306 KkllemlqskglpskSLEDDNERTR-RMAEAESQVSHLEVILDQKEKENIHLREELhrrsqlqpepaktKALQTVIEMKD 384
Cdd:pfam19220 100 R--------------EAEAAKEELRiELRDKTAQAEALERQLAAETEQNRALEEEN-------------KALREEAQAAE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 385 TKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSnqn 464
Cdd:pfam19220 153 KALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAE--- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 465 sdckqhievlkeslTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL 544
Cdd:pfam19220 230 --------------AQLEEAVEAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 545 QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD 624
Cdd:pfam19220 296 ERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANRR 375
|
410
....*....|....*
gi 1958683006 625 LKEkvnALQAELTEK 639
Cdd:pfam19220 376 LKE---ELQRERAER 387
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
435-595 |
9.68e-04 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 41.43 E-value: 9.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 435 KIDQLKQELSKKESELLALQTKLETL--------------SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 500
Cdd:pfam15619 12 KIKELQNELAELQSKLEELRKENRLLkrlqkrqekalgkyEGTESELPQLIARHNEEVRVLRERLRRLQEKERDLERKLK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 501 EKESFL---NKKTKQLQDLTEEKG-----TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdKQLTNLKDRVKSL 572
Cdd:pfam15619 92 EKEAELlrlRDQLKRLEKLSEDKNlaereELQKKLEQLEAKLEDKDEKIQDLERKLELENKSFR---RQLAAEKKKHKEA 168
|
170 180
....*....|....*....|...
gi 1958683006 573 QTDSSNTDTALATLEEALSEKER 595
Cdd:pfam15619 169 QEEVKILQEEIERLQQKLKEKER 191
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
325-904 |
9.71e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 43.24 E-value: 9.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 325 DNERTRRmaEAESQVSHLEVILDQKEKENIHLREELHRrsqLQPEPAKTKALQTVIEMKDTK----IASLERNIRDLEDE 400
Cdd:pfam01576 402 DSEHKRK--KLEGQLQELQARLSESERQRAELAEKLSK---LQSELESVSSLLNEAEGKNIKlskdVSSLESQLQDTQEL 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 401 IQmlkangvlntedreEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTA 480
Cdd:pfam01576 477 LQ--------------EETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEA 542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 481 KEQRAAILQTEVDALRLRLEEKE-------------------------------SFLNKKTKQL-QDLTEEKG------- 521
Cdd:pfam01576 543 LEEGKKRLQRELEALTQQLEEKAaaydklektknrlqqelddllvdldhqrqlvSNLEKKQKKFdQMLAEEKAisaryae 622
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 522 -----------------TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALA 584
Cdd:pfam01576 623 erdraeaeareketralSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLE 702
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 585 TLEEALSEKERIIERL-------KEQRERDDRERLEEIEsfrkenkdlkEKVNALQAELTEKESSLIDLKEHASSLASAG 657
Cdd:pfam01576 703 ELEDELQATEDAKLRLevnmqalKAQFERDLQARDEQGE----------EKRRQLVKQVRELEAELEDERKQRAQAVAAK 772
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 658 LKRDSKLKSLEIAIE---QKKEEC----NKLEAQLKKAHNIEDDSRMN-PEFADRLKQLDKEASyyrdecgKAQAEVDRL 729
Cdd:pfam01576 773 KKLELDLKELEAQIDaanKGREEAvkqlKKLQAQMKDLQRELEEARASrDEILAQSKESEKKLK-------NLEAELLQL 845
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 730 LEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVrrredsmvdNSQHLQIEELMNALEKTR 809
Cdd:pfam01576 846 QEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEEL---------EEEQSNTELLNDRLRKST 916
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 810 QELDATKARLASTQQSLAEKEAhlanlrmeRRKQLEEilemkqeallaaiSEKDANIALLELSASKKKKTQEEVMALKRE 889
Cdd:pfam01576 917 LQVEQLTTELAAERSTSQKSES--------ARQQLER-------------QNKELKAKLQEMEGTVKSKFKSSIAALEAK 975
|
650
....*....|....*
gi 1958683006 890 KDRLVHQLKQQTQNR 904
Cdd:pfam01576 976 IAQLEEQLEQESRER 990
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
613-843 |
1.00e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 613 EEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIE 692
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 693 DDSRmnPEFADRLKQLDKEASYYRDECGKAQ---AEVDRLLEILKEVENEKNdkdKKIAELERHMKDQNKKvanlkhNQQ 769
Cdd:COG4942 100 EAQK--EELAELLRALYRLGRQPPLALLLSPedfLDAVRRLQYLKYLAPARR---EQAEELRADLAELAAL------RAE 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 770 LEKKKN--AQLLEEVRRREDSMvdNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQ 843
Cdd:COG4942 169 LEAERAelEALLAELEEERAAL--EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
346-502 |
1.18e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 346 LDQKEKENIHLREEL-HRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANgVLNTEDREEEIKQIEV 424
Cdd:COG1579 15 LDSELDRLEHRLKELpAELAELE---DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-IKKYEEQLGNVRNNKE 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958683006 425 YKSHSKfmktKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 502
Cdd:COG1579 91 YEALQK----EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
230-566 |
1.33e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.02 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 230 DELRTQRDLnhlLQQESGNRGAEHFTIELTEENFRRLQAEHDRQA------KELFLLRKTLEEME---LRIETQKQTLNA 300
Cdd:PRK04863 789 EQLRAEREE---LAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadpeAELRQLNRRRVELEralADHESQEQQQRS 865
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 301 RDESIKKLLEMLQsKGLPSKSLEDDNERTRRMAEAESQVSHLEV----------ILDQKEKENIHLREELHRRSQLQPEP 370
Cdd:PRK04863 866 QLEQAKEGLSALN-RLLPRLNLLADETLADRVEEIREQLDEAEEakrfvqqhgnALAQLEPIVSVLQSDPEQFEQLKQDY 944
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 371 AKTKALQTVIEMKDTKIASLERNIRDL--EDEIQMLKANGVLNtedreeeikqievykshskfmktkiDQLKQELSKKES 448
Cdd:PRK04863 945 QQAQQTQRDAKQQAFALTEVVQRRAHFsyEDAAEMLAKNSDLN-------------------------EKLRQRLEQAEQ 999
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 449 ELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESflnkktKQLQDLTEEKGTLAGEIR 528
Cdd:PRK04863 1000 ERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAE------ERARARRDELHARLSANR 1073
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1958683006 529 DMKDMLEVK----ERKINVLQKKIENLQEQLRDKDKQLTNLK 566
Cdd:PRK04863 1074 SRRNQLEKQltfcEAEMDNLTKKLRKLERDYHEMREQVVNAK 1115
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
281-615 |
1.37e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 281 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL 360
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 361 HRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKAN-----------GVLNTEDREEEIKQIEVYKSHS 429
Cdd:COG4913 692 EQLEELE---AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRleaaedlarleLRALLEERFAAALGDAVERELR 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 430 KFMKTKIDQLKQELSKKESELLALQTKLetlsnqNSDCKQHIEVLKESLTAKEQRAAILqTEVDALRL-RLEEK-ESFLN 507
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERAMRAF------NREWPAETADLDADLESLPEYLALL-DRLEEDGLpEYEERfKELLN 841
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 508 KKTKQlqDLTEEKGTLAGEIRDMKDMLEvkerKIN-VLQKKIENLQE--QLRDKDKQLTNLKDRVKSLQTDSSNTDTAla 584
Cdd:COG4913 842 ENSIE--FVADLLSKLRRAIREIKERID----PLNdSLKRIPFGPGRylRLEARPRPDPEVREFRQELRAVTSGASLF-- 913
|
330 340 350
....*....|....*....|....*....|....*.
gi 1958683006 585 tlEEALSEK-----ERIIERLKEQRERDDRERLEEI 615
Cdd:COG4913 914 --DEELSEArfaalKRLIERLRSEEEESDRRWRARV 947
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
342-908 |
1.37e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.12 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 342 LEVILDQKEKENIHLREELHR-RSQLQPEPAKTKALQTviEMKDTKIASLERNIRDLEDEIQMLKANgvLNTEDREEEIK 420
Cdd:TIGR01612 680 LSSIVKENAIDNTEDKAKLDDlKSKIDKEYDKIQNMET--ATVELHLSNIENKKNELLDIIVEIKKH--IHGEINKDLNK 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 421 QIEVYKSHSKFMKTKIDqlkqELSKKESELLALQTKLETLSNQNSDckqhievlkesltakeqraailQTEVDalRLRLE 500
Cdd:TIGR01612 756 ILEDFKNKEKELSNKIN----DYAKEKDELNKYKSKISEIKNHYND----------------------QINID--NIKDE 807
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 501 EKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDS---- 576
Cdd:TIGR01612 808 DAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEKIDSEHEQFAELTNKIKAEISDDklnd 887
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 577 -----SNTDTALATLEEALSEKERIIERLKEQRE--RDDRERLEEIESFRKENKDLKEKVNalQAELTEKESSLID---- 645
Cdd:TIGR01612 888 yekkfNDSKSLINEINKSIEEEYQNINTLKKVDEyiKICENTKESIEKFHNKQNILKEILN--KNIDTIKESNLIEksyk 965
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 646 ------LKEHASSLASAglKRDSKLKSLEIAIEQKKEECNKLEAQLKKA------HNIEDDSRMNPEFADRLKQLDKE-- 711
Cdd:TIGR01612 966 dkfdntLIDKINELDKA--FKDASLNDYEAKNNELIKYFNDLKANLGKNkenmlyHQFDEKEKATNDIEQKIEDANKNip 1043
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 712 -------ASYYR--DECGKAQAEVDRLL--EILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEK-------- 772
Cdd:TIGR01612 1044 nieiaihTSIYNiiDEIEKEIGKNIELLnkEILEEAEINITNFNEIKEKLKHYNFDDFGKEENIKYADEINKikddiknl 1123
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 773 ----KKNAQLLEEVRRREDSMVDNSQhLQIEELMNALEKTRQELDATKarLASTQQSLAEKEAHLANLRMERRKQLEEIL 848
Cdd:TIGR01612 1124 dqkiDHHIKALEEIKKKSENYIDEIK-AQINDLEDVADKAISNDDPEE--IEKKIENIVTKIDKKKNIYDEIKKLLNEIA 1200
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958683006 849 EM-KQEALLAAISE------KDANIALLELSASKKKKTQEEVMALKREKDRLvHQLKQQTQNRMKLM 908
Cdd:TIGR01612 1201 EIeKDKTSLEEVKGinlsygKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDL-DEIKEKSPEIENEM 1266
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
580-686 |
1.57e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.76 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 580 DTALA-------TLEEALSEKERIIERLKEQRER----DDRERLEEIESFRKENKDLKEKVNALQAELtEKESSLIdlkE 648
Cdd:COG0542 396 DEAAArvrmeidSKPEELDELERRLEQLEIEKEAlkkeQDEASFERLAELRDELAELEEELEALKARW-EAEKELI---E 471
|
90 100 110
....*....|....*....|....*....|....*...
gi 1958683006 649 HASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK 686
Cdd:COG0542 472 EIQELKEELEQRYGKIPELEKELAELEEELAELAPLLR 509
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
721-902 |
1.61e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 721 KAQAEVDRLLEILKEVENEKN------DKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQL-LEEVRRREDSMVDNS 793
Cdd:TIGR02168 183 RTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELALLVLRLEELREELEELQEeLKEAEEELEELTAEL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 794 Q--HLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRmERRKQLEEILEMKQEALLAAISEKDANIALLEL 871
Cdd:TIGR02168 263 QelEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR-ERLANLERQLEELEAQLEELESKLDELAEELAE 341
|
170 180 190
....*....|....*....|....*....|.
gi 1958683006 872 SASKKKKTQEEVMALKREKDRLVHQLKQQTQ 902
Cdd:TIGR02168 342 LEEKLEELKEELESLEAELEELEAELEELES 372
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
746-900 |
1.76e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 746 KIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEElmnALEKTRQELDATKARLASTQQS 825
Cdd:PRK12705 37 RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEE---QLDARAEKLDNLENQLEEREKA 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 826 LAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQ 900
Cdd:PRK12705 114 LSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAERKAQNILAQAMQR 188
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
506-900 |
1.80e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.59 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 506 LNKKTKQlQDLTEEKGTLAGEIRDMKDMLEVKER---KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSlQTDSSNTDTA 582
Cdd:PRK11281 45 LDALNKQ-KLLEAEDKLVQQDLEQTLALLDKIDRqkeETEQLKQQLAQAPAKLRQAQAELEALKDDNDE-ETRETLSTLS 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 583 LATLEEALSEkeriieRLKEQRErddrerleeiesfrkenkdlkekvnaLQAELTEKESSLIDLK---EHASSLASAGLK 659
Cdd:PRK11281 123 LRQLESRLAQ------TLDQLQN--------------------------AQNDLAEYNSQLVSLQtqpERAQAALYANSQ 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 660 R----DSKLKSLEIAIEQ-KKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEAsyyRDECGKAQAEVDRLLEILK 734
Cdd:PRK11281 171 RlqqiRNLLKGGKVGGKAlRPSQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQ 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 735 EVENEKNDK--DKKIAELERhMKDQNKKVAN------LKHNQQLEKKknaqLLEEVRR---------REDSMVDNSQHLQ 797
Cdd:PRK11281 248 EAINSKRLTlsEKTVQEAQS-QDEAARIQANplvaqeLEINLQLSQR----LLKATEKlntltqqnlRVKNWLDRLTQSE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 798 --IEELMNALE----------KTRQEL--DATKARLAS------------TQQ--SLAEKEAHLANLRM--------ERR 841
Cdd:PRK11281 323 rnIKEQISVLKgslllsrilyQQQQALpsADLIEGLADriadlrleqfeiNQQrdALFQPDAYIDKLEAghksevtdEVR 402
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958683006 842 KQLEEILEMKQEALLAAISEKDANIAL---LELsaskkkkTQEEVMALkreKDRLVHQLKQQ 900
Cdd:PRK11281 403 DALLQLLDERRELLDQLNKQLNNQLNLainLQL-------NQQQLLSV---SDSLQSTLTQQ 454
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
420-547 |
1.85e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 41.72 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 420 KQIEVYKSHSKFMKTKIDQLKQELSKKESE----------LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ 489
Cdd:pfam15905 184 GKLQVTQKNLEHSKGKVAQLEEKLVSTEKEkieeksetekLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESLK 263
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 490 TEVDALRLRLEEKESFLNKKTKQLQDLTEEK--------GTLAGEIRDMKDMLEVKERKINVLQKK 547
Cdd:pfam15905 264 QSLEEKEQELSKQIKDLNEKCKLLESEKEELlreyeekeQTLNAELEELKEKLTLEEQEHQKLQQK 329
|
|
| DUF4618 |
pfam15397 |
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins ... |
420-648 |
1.88e-03 |
|
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins in this family are typically between 238 and 363 amino acids in length. There are two conserved sequence motifs: EYP and KCTPD.
Pssm-ID: 464704 [Multi-domain] Cd Length: 258 Bit Score: 41.48 E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 420 KQIEVYKSHSKFMKTKIDQLKQEL-------SKKESELLALQTKLETLsnqnsdckqhIEVLKESLtakeqraailQTEV 492
Cdd:pfam15397 6 TSLEELKKHEDFLTKLNLELIKAIqdtedstALKVRKLLQQYEKFGTI----------ISILEYSN----------KKQL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 493 DALRLRLEEKESFLNKKTKQLQDLTEEkgtLAGEIRDMKDMLEV----KERKINVLQKKIENLQEQLRD-KDKQLTNLKD 567
Cdd:pfam15397 66 QQAKAELQEWEEKEESKLNKLEQQLEQ---LNAKIQKTQEELNFlstyKDKEYPVKAVQIANLVRQLQQlKDSQQDELDE 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 568 RVKSLQTDssntdtaLATLEEALSEKERII------------ERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAE 635
Cdd:pfam15397 143 LEEMRRMV-------LESLSRKIQKKKEKIlsslaektlspyQESLLQKTRDNQVMLKEIEQFREFIDELEEEIPKLKAE 215
|
250
....*....|...
gi 1958683006 636 LTEKESSLIDLKE 648
Cdd:pfam15397 216 VQQLQAQRQEPRE 228
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
495-635 |
1.94e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 41.54 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 495 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerkinVLQKKIENLQEQLRDKDK----QLTNLKDRVK 570
Cdd:smart00787 145 LKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKD----------ALEEELRQLKQLEDELEDcdptELDRAKEKLK 214
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 571 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRErDDRERLEEIESFRKENKD--------LKEKVNALQAE 635
Cdd:smart00787 215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKS-ELNTEIAEAEKKLEQCRGftfkeiekLKEQLKLLQSL 286
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
531-712 |
2.01e-03 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 41.91 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 531 KDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKdrvKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE 610
Cdd:pfam05262 198 RDMTDLKERESQEDAKRAQQLKEELDKKQIDADKAQ---QKADFAQDNADKQRDEVRQKQQEAKNLPKPADTSSPKEDKQ 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 611 RLEEiesfrkenkdLKEKVNALQAELTEKESSLIDLKEHASSlasaGLKRDSKlksleiaIEQKKEECNKLEAQLKKAHN 690
Cdd:pfam05262 275 VAEN----------QKREIEKAQIEIKKNDEEALKAKDHKAF----DLKQESK-------ASEKEAEDKELEAQKKREPV 333
|
170 180
....*....|....*....|..
gi 1958683006 691 IEDDSRMNPEFADRLKQLDKEA 712
Cdd:pfam05262 334 AEDLQKTKPQVEAQPTSLNEDA 355
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
333-525 |
2.17e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.74 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 333 AEAESQVSHLEVILDQKEKENIHLREELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKA----- 406
Cdd:COG3883 12 AFADPQIQAKQKELSELQAELEAAQAELDAlQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREelger 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 407 ------NG--------VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIE 472
Cdd:COG3883 92 aralyrSGgsvsyldvLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 473 VLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 525
Cdd:COG3883 172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
471-698 |
2.30e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 41.43 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 471 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIEN 550
Cdd:COG1340 3 TDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 551 LQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT---ALATLE-----------------EALSEKERIIERLKEQRERDD-- 608
Cdd:COG1340 83 LNEKLNELREELDELRKELAELNKAGGSIDKlrkEIERLEwrqqtevlspeeekelvEKIKELEKELEKAKKALEKNEkl 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 609 RERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAG-------LKRDSKLKSLEIAIEQKKEECNKL 681
Cdd:COG1340 163 KELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEAdelhkeiVEAQEKADELHEEIIELQKELREL 242
|
250
....*....|....*..
gi 1958683006 682 EAQLKKAHNIEDDSRMN 698
Cdd:COG1340 243 RKELKKLRKKQRALKRE 259
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
583-900 |
2.74e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 583 LATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS--AGLKR 660
Cdd:COG4717 44 RAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREelEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 661 DSKLKSLEIAIEQKKEECNKLEAQLKKAHnieddsrmnpEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEvenek 740
Cdd:COG4717 124 LLQLLPLYQELEALEAELAELPERLEELE----------ERLEELRELEEELEELEAELAELQEELEELLEQLSL----- 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 741 nDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMN----------------- 803
Cdd:COG4717 189 -ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallallglggs 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 804 --ALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQE 881
Cdd:COG4717 268 llSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE 347
|
330
....*....|....*....
gi 1958683006 882 EVMALKREKDRLVHQLKQQ 900
Cdd:COG4717 348 ELQELLREAEELEEELQLE 366
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
387-639 |
3.39e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 41.38 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 387 IASLERNIRDLEDEIQM----------LKANGVLN-----TEDREEEIKQI-EVYKSHSKFMKTKIDQLK---QELSKKE 447
Cdd:pfam06160 148 IDELEKQLAEIEEEFSQfeeltesgdyLEAREVLEkleeeTDALEELMEDIpPLYEELKTELPDQLEELKegyREMEEEG 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 448 SEL--LALQTKLETLSNQNSDCKQHIEVLK--------ESLTAK-EQRAAILQTEVDALRL---RLEEKESFLNKKTKQL 513
Cdd:pfam06160 228 YALehLNVDKEIQQLEEQLEENLALLENLEldeaeealEEIEERiDQLYDLLEKEVDAKKYvekNLPEIEDYLEHAEEQN 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 514 QDLTEEKGTL----------AGEIRDMKDMLEVKERKINVLQKKIEN-------LQEQLRDKDKQLTN-------LKDRV 569
Cdd:pfam06160 308 KELKEELERVqqsytlneneLERVRGLEKQLEELEKRYDEIVERLEEkevayseLQEELEEILEQLEEieeeqeeFKESL 387
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958683006 570 KSLQTDSSNTDTALATLEEALSEKERIIERLkeqrerddreRLEEI-ESFRKENKDLKEKVNALQAELTEK 639
Cdd:pfam06160 388 QSLRKDELEAREKLDEFKLELREIKRLVEKS----------NLPGLpESYLDYFFDVSDEIEDLADELNEV 448
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
416-857 |
3.98e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 40.97 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 416 EEEIKQIEVYKSHSKFMKTK--IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAkeqraaiLQTEVD 493
Cdd:PRK04778 85 EEQLFEAEELNDKFRFRKAKheINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRE-------LRKSLL 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 494 ALRLRLEEKESFLNKKTKQLQDLTEEKGTL--AGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDK----QLTNLKD 567
Cdd:PRK04778 158 ANRFSFGPALDELEKQLENLEEEFSQFVELteSGDYVEAREILDQLEEELAALEQIMEEIPELLKELQTelpdQLQELKA 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 568 RVKSLQT-----DSSNTDTALATLEEALSEKERIIERLkeqrerddrerleEIESFRKENKDLKEKVNALQaELTEKE-S 641
Cdd:PRK04778 238 GYRELVEegyhlDHLDIEKEIQDLKEQIDENLALLEEL-------------DLDEAEEKNEEIQERIDQLY-DILEREvK 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 642 SLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDD-SRMNPEFADRLKQLDKEASYYRDecg 720
Cdd:PRK04778 304 ARKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQlESLEKQYDEITERIAEQEIAYSE--- 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 721 kAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKhnqqlekkknaQLLEEVRRR----------ED--S 788
Cdd:PRK04778 381 -LQEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYR-----------NKLHEIKRYleksnlpglpEDylE 448
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958683006 789 MVDNSQHlQIEELMNALEKTRQELDAtkarlasTQQSLAEKEAHLANLRmerrkqlEEILEMKQEALLA 857
Cdd:PRK04778 449 MFFEVSD-EIEALAEELEEKPINMEA-------VNRLLEEATEDVETLE-------EETEELVENATLT 502
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
768-907 |
4.64e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.52 E-value: 4.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 768 QQLEKKKNAQLLEEVRRREDSMVDNSQHLQ--IEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMER---RK 842
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKkeEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIaelRA 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958683006 843 QLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 907
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162
|
|
| XRN1 |
COG5049 |
5'-3' exonuclease [Replication, recombination and repair]; |
238-440 |
4.79e-03 |
|
5'-3' exonuclease [Replication, recombination and repair];
Pssm-ID: 227382 [Multi-domain] Cd Length: 953 Bit Score: 41.06 E-value: 4.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 238 LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGL 317
Cdd:COG5049 366 LAILGSFEDDIFKKDHIQEERKNESLERFSLRKERKEGLKGMPRVVYEQKKLIGSIKPTLMDQLQEKKSPDLPDEEFIDT 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 318 PSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASlernirDL 397
Cdd:COG5049 446 LALPKDLDMKNHELFLKRFANDLGLSISKAIKSKGNYSLEMDIASDSPDEDEEEFESEVDSIRKIPDKYVNI------IV 519
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1958683006 398 EDEIQmlkaNGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLK 440
Cdd:COG5049 520 EEEEE----NETEKTVNLRFPGWKERYYTSKLHFTTDSEEKIR 558
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
447-600 |
4.84e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.50 E-value: 4.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 447 ESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ----------TEVDALRLRLEEKESFLNKKTKQLQDL 516
Cdd:pfam13851 32 KEEIAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRkqlenyekdkQSLKNLKARLKVLEKELKDLKWEHEVL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 517 TEEKGTLAGEIRDMKDM-----LEVKER---KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDtalATLEE 588
Cdd:pfam13851 112 EQRFEKVERERDELYDKfeaaiQDVQQKtglKNLLLEKKLQALGETLEKKEAQLNEVLAAANLDPDALQAVT---EKLED 188
|
170
....*....|..
gi 1958683006 589 ALSEKERIIERL 600
Cdd:pfam13851 189 VLESKNQLIKDL 200
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
369-764 |
4.93e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 4.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 369 EPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQmlKANGVLNTEDREEeiKQIEVYKSHSKFMKTKIDQLKQELSKkes 448
Cdd:TIGR01612 1460 EMADNKSQHILKIKKDNATNDHDFNINELKEHID--KSKGCKDEADKNA--KAIEKNKELFEQYKKDVTELLNKYSA--- 1532
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 449 elLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT------EEKGT 522
Cdd:TIGR01612 1533 --LAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQlslenfENKFL 1610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 523 LAGEIR----DMKDMLEVKERKINVLQkkIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIE 598
Cdd:TIGR01612 1611 KISDIKkkinDCLKETESIEKKISSFS--IDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEI 1688
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 599 RLKEQRERDDRERLEEIESFRKENKdlkekvNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLksleiaiEQKKEEC 678
Cdd:TIGR01612 1689 DVDQHKKNYEIGIIEKIKEIAIANK------EEIESIKELIEPTIENLISSFNTNDLEGIDPNEKL-------EEYNTEI 1755
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 679 NKLEAQLKKAHNIeddsrmnpeFADRLKQLDKEASYYrDECGKAQAEVDRllEILKEVENEKNDK----DKKIAELERHM 754
Cdd:TIGR01612 1756 GDIYEEFIELYNI---------IAGCLETVSKEPITY-DEIKNTRINAQN--EFLKIIEIEKKSKsyldDIEAKEFDRII 1823
|
410
....*....|
gi 1958683006 755 KDQNKKVANL 764
Cdd:TIGR01612 1824 NHFKKKLDHV 1833
|
|
| Surf_Exclu_PgrA |
TIGR04320 |
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ... |
541-643 |
5.39e-03 |
|
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.
Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 40.48 E-value: 5.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 541 INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESfrk 620
Cdd:TIGR04320 256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNNLATAQAALANAEA--- 332
|
90 100
....*....|....*....|...
gi 1958683006 621 ENKDLKEKVNALQAELTEKESSL 643
Cdd:TIGR04320 333 RLAKAKEALANLNADLAKKQAAL 355
|
|
| MPS2 |
pfam17060 |
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component ... |
472-607 |
5.50e-03 |
|
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component of the spindle pole body (SPB) required for the insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. It seems that Mps2-Spc24 interaction may contribute to the localization of Spc24 and other kinetochore components to the inner plaque of the SPB.
Pssm-ID: 407228 [Multi-domain] Cd Length: 340 Bit Score: 40.34 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 472 EVLKESLTAKEQRAAILQTEVDALRLRLEEKES------FLNKKTKQLQDLTEekgTLAGEIRDMKDMLEVKERKINVLQ 545
Cdd:pfam17060 105 ELKEDVKSSPRSEADSLGTPIKVDLLRNLKPQEspetprRINRKYKSLELRVE---SMKDELEFKDETIMEKDRELTELT 181
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 546 KKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT----ALATLEEALSEKERIIERLKEQRERD 607
Cdd:pfam17060 182 STISKLKDKYDFLSREFEFYKQHHEHGGNNSIKTATkhefIISELKRKLQEQNRLIRILQEQIQFD 247
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
531-854 |
5.57e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 40.77 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 531 KDMLEVKERkinvLQKKIENLQEQL-RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA--LSEKERIIERLKEQRERD 607
Cdd:NF033838 58 EHAKEVESH----LEKILSEIQKSLdKRKHTQNVALNKKLSDIKTEYLYELNVLKEKSEAelTSKTKKELDAAFEQFKKD 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 608 DRERLEE-------IESFRKENKDLKEK------VNALQAELTEKESSLIDLKEHASSLASAGLKR---DSKLKSLEIAI 671
Cdd:NF033838 134 TLEPGKKvaeatkkVEEAEKKAKDQKEEdrrnypTNTYKTLELEIAESDVEVKKAELELVKEEAKEprdEEKIKQAKAKV 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 672 EQKKEECNKLEAQLKKAHNIEDDSrmnPEFADRLKQLDKEASYYRDECGKAQAEVDRllEILKEV------ENEKNDKDK 745
Cdd:NF033838 214 ESKKAEATRLEKIKTDREKAEEEA---KRRADAKLKEAVEKNVATSEQDKPKRRAKR--GVLGEPatpdkkENDAKSSDS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 746 KIAE--LERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQ 823
Cdd:NF033838 289 SVGEetLPSPSLKPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKEPRNE 368
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1958683006 824 ----QSLAEKEAHLAN-LRMER----RKQLEEilEMKQEA 854
Cdd:NF033838 369 ekikQAKAKVESKKAEaTRLEKiktdRKKAEE--EAKRKA 406
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
219-554 |
5.80e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 5.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 219 QHlQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKelfllrKTLEEMELRIETQKQTL 298
Cdd:pfam17380 279 QH-QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAA------IYAEQERMAMERERELE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 299 NARDESIKKLLEMLqskglpsksleddneRTRRMAEAESQVSHLEVILDQKEKENIHLREELH--RRSQLQPEPAKTKAL 376
Cdd:pfam17380 352 RIRQEERKRELERI---------------RQEEIAMEISRMRELERLQMERQQKNERVRQELEaaRKVKILEEERQRKIQ 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 377 QTVIEMKdtKIASLERNIRdlEDEIQMLKangvlntEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTK 456
Cdd:pfam17380 417 QQKVEME--QIRAEQEEAR--QREVRRLE-------EERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 457 LETLSNQNSDC-KQHIEVLKESLTAKEQRAAILQTEVDALRLRL-EEKESFLNKKTKQLQDLTEEKGTLAGEIR---DMK 531
Cdd:pfam17380 486 RKRAEEQRRKIlEKELEERKQAMIEEERKRKLLEKEMEERQKAIyEEERRREAEEERRKQQEMEERRRIQEQMRkatEER 565
|
330 340
....*....|....*....|...
gi 1958683006 532 DMLEVKERKINVLQKKIENLQEQ 554
Cdd:pfam17380 566 SRLEAMEREREMMRQIVESEKAR 588
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
381-970 |
5.94e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 40.81 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 381 EMKDTKIASLERNIRDLEDEIQMLkangvlnTEDREEEIKQIEVYKSHSKFMKTkIDQLKQELSKKESEllalQTKLETL 460
Cdd:TIGR01612 879 EISDDKLNDYEKKFNDSKSLINEI-------NKSIEEEYQNINTLKKVDEYIKI-CENTKESIEKFHNK----QNILKEI 946
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 461 SNQNSDCKQHIEVLKESLTAKEQRAAILQ-TEVDAL--RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIrdMKDMLEVK 537
Cdd:TIGR01612 947 LNKNIDTIKESNLIEKSYKDKFDNTLIDKiNELDKAfkDASLNDYEAKNNELIKYFNDLKANLGKNKENM--LYHQFDEK 1024
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 538 ERKINVLQKKIENLQEQLRDKD----KQLTNLKDRVKSL---QTDSSNTDTaLATLEEALSEKERIIERLKEQRERD--- 607
Cdd:TIGR01612 1025 EKATNDIEQKIEDANKNIPNIEiaihTSIYNIIDEIEKEigkNIELLNKEI-LEEAEINITNFNEIKEKLKHYNFDDfgk 1103
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 608 --DRERLEEIESFRKENKDLKEKVNALQAELTE----KESSLIDLKEHASSLASAGLKR---------DSKLKSLEIAIE 672
Cdd:TIGR01612 1104 eeNIKYADEINKIKDDIKNLDQKIDHHIKALEEikkkSENYIDEIKAQINDLEDVADKAisnddpeeiEKKIENIVTKID 1183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 673 QKK---EECNKLEAQL----KKAHNIEDDSRMNPEFADRL-----KQLDKEASYYRDECGKAQAEVDRLLEILK---EVE 737
Cdd:TIGR01612 1184 KKKniyDEIKKLLNEIaeieKDKTSLEEVKGINLSYGKNLgklflEKIDEEKKKSEHMIKAMEAYIEDLDEIKEkspEIE 1263
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 738 NEKNDKDKKIAELE----RHMKDQNKKVANLKHNQQLEKKKNAQL-LEEVRRREDSMVDNSQHLQ------------IEE 800
Cdd:TIGR01612 1264 NEMGIEMDIKAEMEtfniSHDDDKDHHIISKKHDENISDIREKSLkIIEDFSEESDINDIKKELQknlldaqkhnsdINL 1343
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 801 LMNALEKTRQ--ELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALL--------AAISEKDANIALLE 870
Cdd:TIGR01612 1344 YLNEIANIYNilKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeckskieSTLDDKDIDECIKK 1423
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 871 LSASKKKKTQEEV---MALKREKD---------RLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRSQHSN 938
Cdd:TIGR01612 1424 IKELKNHILSEESnidTYFKNADEnnenvlllfKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHIDKSKGCKDEAD 1503
|
650 660 670
....*....|....*....|....*....|..
gi 1958683006 939 HRPSPDQLSEGLAKRIAQHCSDVLIIYCSLAL 970
Cdd:TIGR01612 1504 KNAKAIEKNKELFEQYKKDVTELLNKYSALAI 1535
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
321-554 |
6.32e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.39 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 321 SLEDDNERTRRMAEA-ESQVSHLEVILDQKEKEnihlREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLED 399
Cdd:COG3206 165 NLELRREEARKALEFlEEQLPELRKELEEAEAA----LEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 400 EIQMLKANGVLNtEDREEEIKQIEVYKShskfMKTKIDQLKQELSKKESELLALQTKLETLSNQnsdckqhIEVLKESLT 479
Cdd:COG3206 241 RLAALRAQLGSG-PDALPELLQSPVIQQ----LRAQLAELEAELAELSARYTPNHPDVIALRAQ-------IAALRAQLQ 308
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 480 AKEQRAAI-LQTEVDALRLRLEEKESFLNKKTKQLQDLTEekgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQ 554
Cdd:COG3206 309 QEAQRILAsLEAELEALQAREASLQAQLAQLEARLAELPE----LEAELRRLEREVEVARELYESLLQRLEEARLA 380
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
402-588 |
6.35e-03 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 40.05 E-value: 6.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 402 QMLKANGVLNTEDREEEIKQievyksHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAK 481
Cdd:cd22656 95 EILELIDDLADATDDEELEE------AKKTIKALLDDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDL 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 482 --EQRAAILQTEVDALRlrleekesflnkktKQLQDLTEEkgtlagEIRDMKDmlevkerKINVLQKKIENLQEQLRDKD 559
Cdd:cd22656 169 ltDEGGAIARKEIKDLQ--------------KELEKLNEE------YAAKLKA-------KIDELKALIADDEAKLAAAL 221
|
170 180
....*....|....*....|....*....
gi 1958683006 560 KQLTNLKDRVKSLQTDSSNTDTALATLEE 588
Cdd:cd22656 222 RLIADLTAADTDLDNLLALIGPAIPALEK 250
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
665-820 |
6.82e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.23 E-value: 6.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 665 KSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEfADRLKQLDKEasyyrdecgkaqaeVDRLLEILKEVENEKNDKD 744
Cdd:COG2433 376 LSIEEALEELIEKELPEEEPEAEREKEHEERELTEE-EEEIRRLEEQ--------------VERLEAEVEELEAELEEKD 440
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958683006 745 KKIAELERhmkdqnkkvanlkhnqQLEKKKNAQLLEEVRRREDSMVDNSqhlqIEELMNALEKTRQELDATKARLA 820
Cdd:COG2433 441 ERIERLER----------------ELSEARSEERREIRKDREISRLDRE----IERLERELEEERERIEELKRKLE 496
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
614-765 |
7.33e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.14 E-value: 7.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 614 EIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLasaglkrDSKLKSLEIAIEQKKEECNKLEAQLKKAHN--- 690
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDL-------EKEIKRLELEIEEVEARIKKYEEQLGNVRNnke 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 691 -------IEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEkndKDKKIAELERHMKDQNKKVAN 763
Cdd:COG1579 91 yealqkeIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE---LDEELAELEAELEELEAEREE 167
|
..
gi 1958683006 764 LK 765
Cdd:COG1579 168 LA 169
|
|
| hsdR |
PRK11448 |
type I restriction enzyme EcoKI subunit R; Provisional |
544-663 |
7.54e-03 |
|
type I restriction enzyme EcoKI subunit R; Provisional
Pssm-ID: 236912 [Multi-domain] Cd Length: 1123 Bit Score: 40.32 E-value: 7.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 544 LQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEiesFRKENK 623
Cdd:PRK11448 147 LQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQK---RKEITD 223
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1958683006 624 DLKEKVnalqaELTEKES-SLIDlkehaSSLASAGLKRDSK 663
Cdd:PRK11448 224 QAAKRL-----ELSEEETrILID-----QQLRKAGWEADSK 254
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
720-853 |
8.50e-03 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 38.71 E-value: 8.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 720 GKAQAEVDRLLE--------ILKEVENEKNDKDKKI-AELERHMKDQNKKVanlkhnQQLEKKknaqlleeVRRREDSmv 790
Cdd:pfam12072 30 GSAEELAKRIIEeakkeaetKKKEALLEAKEEIHKLrAEAERELKERRNEL------QRQERR--------LLQKEET-- 93
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958683006 791 dnsqhlqIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQE 853
Cdd:pfam12072 94 -------LDRKDESLEKKEESLEKKEKELEAQQQQLEEKEEELEELIEEQRQELERISGLTSE 149
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
700-891 |
8.66e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.00 E-value: 8.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 700 EFADRLKQLDKEASYYRDECGKAQAEVDRLLE--ILKEVENEKNDKDKKIAELerhmkdqNKKVANLKHNQQLEKKKNAQ 777
Cdd:COG3206 172 EARKALEFLEEQLPELRKELEEAEAALEEFRQknGLVDLSEEAKLLLQQLSEL-------ESQLAEARAELAEAEARLAA 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958683006 778 LLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEIL---EMKQEA 854
Cdd:COG3206 245 LRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILaslEAELEA 324
|
170 180 190
....*....|....*....|....*....|....*..
gi 1958683006 855 LLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 891
Cdd:COG3206 325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVE 361
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