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Conserved domains on  [gi|1039778874|ref|XP_017177783|]
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RCC1 domain-containing protein 1 isoform X1 [Mus musculus]

Protein Classification

RCC1 domain-containing protein( domain architecture ID 11474102)

RCC1 (regulator of chromosome condensation) domain-containing protein similar to Arabidopsis UVR8 (UV RESISTANCE LOCUS 8), which plays an important role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway.

Gene Ontology:  GO:0003682|GO:0005085
PubMed:  9510255|18442486

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 163-344 9.22e-24

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 100.44  E-value: 9.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 163 VRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRmaKVAAGGWHSVCLSETGDIYIWGWNES 242
Cdd:COG5184   151 VVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSGVV--AVAAGGDHSCALKSDGTVWCWGSNSS 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 243 GQLALPTRSGtenkaereeatelnedglkeelavadagapahfiaiQPFPALldLPLGSDAVMASCGSRHTAVVTRTGEL 322
Cdd:COG5184   229 GQLGDGTTTD------------------------------------RATPVQ--VAGLTGVVAIAAGGSHTCALKSDGTV 270

                         170       180
                  ....*....|....*....|..
gi 1039778874 323 YTWGWGKYGQLGHKDSTSLDRP 344
Cdd:COG5184   271 WCWGDNSYGQLGDGTTTDRSTP 292
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 163-344 9.22e-24

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 100.44  E-value: 9.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 163 VRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRmaKVAAGGWHSVCLSETGDIYIWGWNES 242
Cdd:COG5184   151 VVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSGVV--AVAAGGDHSCALKSDGTVWCWGSNSS 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 243 GQLALPTRSGtenkaereeatelnedglkeelavadagapahfiaiQPFPALldLPLGSDAVMASCGSRHTAVVTRTGEL 322
Cdd:COG5184   229 GQLGDGTTTD------------------------------------RATPVQ--VAGLTGVVAIAAGGSHTCALKSDGTV 270

                         170       180
                  ....*....|....*....|..
gi 1039778874 323 YTWGWGKYGQLGHKDSTSLDRP 344
Cdd:COG5184   271 WCWGDNSYGQLGDGTTTDRSTP 292
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
180-228 1.32e-15

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 70.24  E-value: 1.32e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1039778874 180 GQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRMAKVAAGGWHSVCL 228
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 163-344 9.22e-24

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 100.44  E-value: 9.22e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 163 VRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRmaKVAAGGWHSVCLSETGDIYIWGWNES 242
Cdd:COG5184   151 VVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSGVV--AVAAGGDHSCALKSDGTVWCWGSNSS 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 243 GQLALPTRSGtenkaereeatelnedglkeelavadagapahfiaiQPFPALldLPLGSDAVMASCGSRHTAVVTRTGEL 322
Cdd:COG5184   229 GQLGDGTTTD------------------------------------RATPVQ--VAGLTGVVAIAAGGSHTCALKSDGTV 270

                         170       180
                  ....*....|....*....|..
gi 1039778874 323 YTWGWGKYGQLGHKDSTSLDRP 344
Cdd:COG5184   271 WCWGDNSYGQLGDGTTTDRSTP 292
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 162-369 2.01e-21

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 93.89  E-value: 2.01e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 162 RVRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRMakVAAGGWHSVCLSETGDIYIWGWNE 241
Cdd:COG5184    49 NVVAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRTTPVKVPGLTGVVA--VAAGYYHSCALKSDGTVWCWGDNS 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 242 SGQLALPTRSGTENkaereeatelnedglkeelavadagapahfiaiqpfPALLDLPLgSDAVMASCGSRHTAVVTRTGE 321
Cdd:COG5184   127 SGQLGDGTTTNRLT------------------------------------PVQVDAGL-SGVVAIAAGGYHTCALKSDGT 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1039778874 322 LYTWGWGKYGQLGHKDSTSLDRPccveYFVERQLEVRAVTCGPWNTYV 369
Cdd:COG5184   170 VWCWGANSYGQLGDGTTTDRPTP----VQVGGLSGVVAVAAGGDHSCA 213
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 163-344 2.09e-21

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 93.89  E-value: 2.09e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 163 VRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGlrMAKVAAGGWHSVCLSETGDIYIWGWNES 242
Cdd:COG5184   201 VVAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGTTTDRATPVQVAGLTG--VVAIAAGGSHTCALKSDGTVWCWGDNSY 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 243 GQLALPTRsgtenkaereeatelnedglkeelavADAGAPAhfiaiqpfpallDLPLGSDAVMASCGSRHTAVVTRTGEL 322
Cdd:COG5184   279 GQLGDGTT--------------------------TDRSTPV------------KVPGLSGVVAVAAGSSHTCALLTDGTV 320

                         170       180
                  ....*....|....*....|..
gi 1039778874 323 YTWGWGKYGQLGhkDSTSLDRP 344
Cdd:COG5184   321 WCWGDNAYGQLG--DGTTTDRS 340
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 164-369 1.32e-20

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 91.58  E-value: 1.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 164 RQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGlrMAKVAAGGWHSVCLSETGDIYIWGWNESG 243
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 244 QLALPTRSGTEnkaereeatelnedglkeelavadagAPAHfiaiqpfpalldLPLGSDAVMASCGSRHTAVVTRTGELY 323
Cdd:COG5184    79 QLGDGTTTDRT--------------------------TPVK------------VPGLTGVVAVAAGYYHSCALKSDGTVW 120

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1039778874 324 TWGWGKYGQLGHKDSTSLDRPCCVEYFVErqlEVRAVTCGPWNTYV 369
Cdd:COG5184   121 CWGDNSSGQLGDGTTTNRLTPVQVDAGLS---GVVAIAAGGYHTCA 163
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
180-228 1.32e-15

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 70.24  E-value: 1.32e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1039778874 180 GQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLRMAKVAAGGWHSVCL 228
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 162-251 4.13e-14

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 72.70  E-value: 4.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039778874 162 RVRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEPRLLEALQGLrmAKVAAGGWHSVCLSETGDIYIWGWNE 241
Cdd:COG5184   250 GVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSGV--VAVAAGSSHTCALLTDGTVWCWGDNA 327

                          90
                  ....*....|
gi 1039778874 242 SGQLALPTRS 251
Cdd:COG5184   328 YGQLGDGTTT 337
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
320-367 1.57e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 50.21  E-value: 1.57e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1039778874 320 GELYTWGWGKYGQLGHKDSTSLDRPCCVEYFVERqlEVRAVTCGPWNT 367
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGN--KVVQVACGGDHT 47
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
216-244 2.86e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 46.26  E-value: 2.86e-07
                          10        20
                  ....*....|....*....|....*....
gi 1039778874 216 AKVAAGGWHSVCLSETGDIYIWGWNESGQ 244
Cdd:pfam13540   2 VSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
307-332 7.84e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 45.11  E-value: 7.84e-07
                          10        20
                  ....*....|....*....|....*.
gi 1039778874 307 SCGSRHTAVVTRTGELYTWGWGKYGQ 332
Cdd:pfam13540   5 AAGDNHTLALTSDGRVYCWGDNSYGQ 30
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 162-204 5.97e-04

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 41.50  E-value: 5.97e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1039778874 162 RVRQLELGAEHVLLLCAAGQVFSWGAGRHGQLGHGTLEAELEP 204
Cdd:COG5184   300 GVVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTP 342
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
163-192 4.41e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 34.32  E-value: 4.41e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1039778874 163 VRQLELGAEHVLLLCAAGQVFSWGAGRHGQ 192
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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