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Conserved domains on  [gi|1039761748|ref|XP_017174711|]
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1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 4-137 5.11e-37

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


:

Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 125.85  E-value: 5.11e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:cd07989    41 LGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALREAIEAL-KEGESVVIFPEGTRSRDGELLPFKS 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039761748  84 GAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDAD 137
Cdd:cd07989   120 GAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIGEPIPPEGLELAE 173
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 4-137 5.11e-37

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 125.85  E-value: 5.11e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:cd07989    41 LGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALREAIEAL-KEGESVVIFPEGTRSRDGELLPFKS 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039761748  84 GAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDAD 137
Cdd:cd07989   120 GAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIGEPIPPEGLELAE 173
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 4-158 1.12e-36

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 126.28  E-value: 1.12e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:COG0204    60 LLAALPRPVRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALRALRQAVEAL-KAGESLVIFPEGTRSPDGRLLPFKT 138

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039761748  84 GAFYLAIQAQVPIIPVVYSSfSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQ 158
Cdd:COG0204   139 GAARLALEAGVPIVPVAIDG-TERALPKGFLPRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRA 212
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 1-102 5.93e-32

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 111.22  E-value: 5.93e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   1 MMGLMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGD 77
Cdd:pfam01553  28 VLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVELL-REGKLVVIFPEGTRSREGE 106

                          90       100
                  ....*....|....*....|....*
gi 1039761748  78 LLPFKKGAFYLAIQAQVPIIPVVYS 102
Cdd:pfam01553 107 LLPFKKGAFRLAIEAGVPIVPVAIS 131
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 4-102 1.28e-28

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 102.43  E-value: 1.28e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748    4 LMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLP 80
Cdd:smart00563  16 LSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELL-KEGEWLLIFPEGTRSRPGKLLP 94

                           90       100
                   ....*....|....*....|..
gi 1039761748   81 FKKGAFYLAIQAQVPIIPVVYS 102
Cdd:smart00563  95 FKKGAARLALEAGVPIVPVAIR 116
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 7-102 7.48e-24

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 90.48  E-value: 7.48e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   7 ILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKKGAF 86
Cdd:TIGR00530  36 AFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAIATALKAAIEVL-KQGRSIGVFPEGTRSRGRDILPFKKGAF 114

                          90
                  ....*....|....*.
gi 1039761748  87 YLAIQAQVPIIPVVYS 102
Cdd:TIGR00530 115 HIAIKAGVPILPVVLS 130
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 1-165 1.40e-16

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 74.28  E-value: 1.40e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   1 MMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGDLLP 80
Cdd:PRK15018   79 MVTASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLP 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748  81 FKKGAFYLAIQAQVPIIPVVYSSFSSfyNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIP 160
Cdd:PRK15018  159 FKTGAFHAAIAAGVPIIPVCVSTTSN--KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQKIAELDKEV 236


                  ....*
gi 1039761748 161 QENSA 165
Cdd:PRK15018  237 AEREA 241
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 4-137 5.11e-37

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 125.85  E-value: 5.11e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:cd07989    41 LGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALREAIEAL-KEGESVVIFPEGTRSRDGELLPFKS 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039761748  84 GAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDAD 137
Cdd:cd07989   120 GAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIGEPIPPEGLELAE 173
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 4-158 1.12e-36

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 126.28  E-value: 1.12e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:COG0204    60 LLAALPRPVRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALRALRQAVEAL-KAGESLVIFPEGTRSPDGRLLPFKT 138

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039761748  84 GAFYLAIQAQVPIIPVVYSSfSSFYNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQ 158
Cdd:COG0204   139 GAARLALEAGVPIVPVAIDG-TERALPKGFLPRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRA 212
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 1-102 5.93e-32

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 111.22  E-value: 5.93e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   1 MMGLMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGD 77
Cdd:pfam01553  28 VLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVELL-REGKLVVIFPEGTRSREGE 106

                          90       100
                  ....*....|....*....|....*
gi 1039761748  78 LLPFKKGAFYLAIQAQVPIIPVVYS 102
Cdd:pfam01553 107 LLPFKKGAFRLAIEAGVPIVPVAIS 131
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 4-102 1.28e-28

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 102.43  E-value: 1.28e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748    4 LMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLP 80
Cdd:smart00563  16 LSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELL-KEGEWLLIFPEGTRSRPGKLLP 94

                           90       100
                   ....*....|....*....|..
gi 1039761748   81 FKKGAFYLAIQAQVPIIPVVYS 102
Cdd:smart00563  95 FKKGAARLALEAGVPIVPVAIR 116
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 7-102 7.48e-24

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 90.48  E-value: 7.48e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   7 ILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKKGAF 86
Cdd:TIGR00530  36 AFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAIATALKAAIEVL-KQGRSIGVFPEGTRSRGRDILPFKKGAF 114

                          90
                  ....*....|....*.
gi 1039761748  87 YLAIQAQVPIIPVVYS 102
Cdd:TIGR00530 115 HIAIKAGVPILPVVLS 130
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 1-165 1.40e-16

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 74.28  E-value: 1.40e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   1 MMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGDLLP 80
Cdd:PRK15018   79 MVTASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLP 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748  81 FKKGAFYLAIQAQVPIIPVVYSSFSSfyNVKTKLFTSGTIKVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISQIP 160
Cdd:PRK15018  159 FKTGAFHAAIAAGVPIIPVCVSTTSN--KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQKIAELDKEV 236


                  ....*
gi 1039761748 161 QENSA 165
Cdd:PRK15018  237 AEREA 241
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 15-100 3.21e-12

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 62.06  E-value: 3.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748  15 IAKRELMFTGPVGLIMYLGGVYFINRQQARTAMSVMADLGDLmVKENLKVWIYPEGTRNDNGDLLPFKKGAFYLAIQAQV 94
Cdd:PLN02901   77 ISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECLKRCMEL-LKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGV 155


                  ....*.
gi 1039761748  95 PIIPVV 100
Cdd:PLN02901  156 PVVPIT 161
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 33-100 1.20e-08

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 52.03  E-value: 1.20e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039761748  33 GGVYFINRQQARTAMSVMADLGDLMVKENLKVWIYPEGTRNDNGD-LLPFKKGAFYLAIQAQVPIIPVV 100
Cdd:cd06551    73 LGAFSVDRDSPRSAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVA 141
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 1-99 2.36e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 47.98  E-value: 2.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   1 MMGLMEILpKRCVQIAKRELMFTGPVGLIM-YLGGVYfINRQQArtamsvmADLGDLMVK-----ENLKVWIYPEGTRND 74
Cdd:cd07988    38 GLLAAFAL-GLKISFLGKHSLFKPPLGPFMrWLGGIP-VDRSRA-------GGLVEQVVEefrrrEEFVLAIAPEGTRSK 108

                          90       100
                  ....*....|....*....|....*
gi 1039761748  75 NGdllPFKKGAFYLAIQAQVPIIPV 99
Cdd:cd07988   109 VD---KWKTGFYHIARGAGVPILLV 130
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 15-109 9.01e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 46.83  E-value: 9.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748  15 IAKRELMFTGPVGLIM-YLGGVYF-----INRQQARTAMSVMADLGDlmvkeNLKVWIYPEGTRNDNGDLLPFKKGAFYL 88
Cdd:cd07991    50 VAKKELGKLPFIGTILrALGCIFVdrsepKDRKKVVEEIKERATDPN-----WPPILIFPEGTTTNGKALIMFKKGAFEP 124

                          90       100
                  ....*....|....*....|...
gi 1039761748  89 aiqaQVPIIPVV--YSSFSSFYN 109
Cdd:cd07991   125 ----GVPVQPVAirYPNKFVDAF 143
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 64-105 4.00e-04

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 39.91  E-value: 4.00e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1039761748   64 VWIYPEGTRNDNGDLLPFKKGaFYLAIQ-AQVPIIPvVY------SSFS 105
Cdd:PRK08633   514 VCIFPEGAITRNGQLNEFKRG-FELIVKgTDVPIIP-FYirglwgSIFS 560
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 4-99 6.51e-03

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 35.70  E-value: 6.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039761748   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQ----ARTAMSVMADLGDLmVKENLK----VWIYPEGTRNDN 75
Cdd:cd07992    46 LAATLRRPVRFLAKADLFKNPLIGWLLESFGAIPVYRPKdlarGGIGKISNAAVFDA-VGEALKaggaIGIFPEGGSHDR 124

                          90       100       110
                  ....*....|....*....|....*....|
gi 1039761748  76 GDLLPFKKGAFYLAIQA------QVPIIPV 99
Cdd:cd07992   125 PRLLPLKAGAARMALEAleagqkDVKIVPV 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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