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Conserved domains on  [gi|1039745236|ref|XP_017171258|]
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cytoplasmic polyadenylated homeobox 1 isoform X1 [Mus musculus]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10052840)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Gene Ontology:  GO:0003677|GO:0006357|GO:0043565
PubMed:  1357790|26464018|21557080

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 29-82 3.22e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


:

Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 56.10  E-value: 3.22e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039745236  29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRARL 82
Cdd:cd00086     2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 29-82 3.22e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 56.10  E-value: 3.22e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039745236  29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRARL 82
Cdd:cd00086     2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 29-81 7.41e-11

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.95  E-value: 7.41e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039745236   29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRAR 81
Cdd:smart00389   3 RKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAK 55
Homeodomain pfam00046
Homeodomain;
29-81 9.73e-10

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 52.12  E-value: 9.73e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1039745236  29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRAR 81
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAK 54
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
15-91 1.94e-06

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 45.51  E-value: 1.94e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039745236  15 NRSKARKRYGSRNSKP-RHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRARLAPELKSKIS 91
Cdd:COG5576    38 EMKLERKQDGSSPPKSkRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVE 115
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 29-82 3.22e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 56.10  E-value: 3.22e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039745236  29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRARL 82
Cdd:cd00086     2 RKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 29-81 7.41e-11

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 54.95  E-value: 7.41e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039745236   29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRAR 81
Cdd:smart00389   3 RKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAK 55
Homeodomain pfam00046
Homeodomain;
29-81 9.73e-10

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 52.12  E-value: 9.73e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1039745236  29 KPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRAR 81
Cdd:pfam00046   2 RKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAK 54
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
15-91 1.94e-06

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 45.51  E-value: 1.94e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039745236  15 NRSKARKRYGSRNSKP-RHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVIDNWFQNKRARLAPELKSKIS 91
Cdd:COG5576    38 EMKLERKQDGSSPPKSkRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRSGKVE 115
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 50-81 4.39e-04

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 36.34  E-value: 4.39e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1039745236  50 PYPDFTTKDELARQFQCEVSVIDNWFQNKRAR 81
Cdd:pfam05920   8 PYPSEEEKAELAKETGLSRKQISNWFINARRR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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