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Conserved domains on  [gi|1039737588|ref|XP_017170131|]
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uncharacterized protein LOC432600 isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
106-152 1.22e-07

Keratin, high sulfur B2 protein;


:

Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 46.22  E-value: 1.22e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1039737588 106 CCISSCCQPRCCISSCCQP-CCRPSCCQSSCCKPCCqpfCLNLCCQPA 152
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPsCCQPSCCQPSCCRPSC---CRSSCCQPT 45
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 61-189 1.86e-06

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 45.94  E-value: 1.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  61 FQPCCVSSCCRTPCCQPCCCvssccqpccqpscchccQSSCCQPRCCISSCCQPRCCISSCCQPCCRPSCCQSSCCKPCC 140
Cdd:pfam01500  11 FPTCSTGGTCGSGCCQPCCC-----------------QSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQTSCCQPTCC 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039737588 141 QPFCLNLCC------QPACSGPVTCTRTCYQPTCVCVPGCLSQGCGSSCCEPCGC 189
Cdd:pfam01500  74 QTSSCQTGCggigygQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCC 128
 
Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
106-152 1.22e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 46.22  E-value: 1.22e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1039737588 106 CCISSCCQPRCCISSCCQP-CCRPSCCQSSCCKPCCqpfCLNLCCQPA 152
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPsCCQPSCCQPSCCRPSC---CRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 61-189 1.86e-06

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 45.94  E-value: 1.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  61 FQPCCVSSCCRTPCCQPCCCvssccqpccqpscchccQSSCCQPRCCISSCCQPRCCISSCCQPCCRPSCCQSSCCKPCC 140
Cdd:pfam01500  11 FPTCSTGGTCGSGCCQPCCC-----------------QSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQTSCCQPTCC 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039737588 141 QPFCLNLCC------QPACSGPVTCTRTCYQPTCVCVPGCLSQGCGSSCCEPCGC 189
Cdd:pfam01500  74 QTSSCQTGCggigygQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCC 128
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
64-153 4.02e-04

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 40.30  E-value: 4.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  64 CCVSSCCRTPCCQPCCCVSSCCQPCCQPSCCHCCQSSCCQPRCCISSCCQPRCCISSCCQPCCRPSCCQssCCKPCCQPF 143
Cdd:COG3901   594 LLLLLLLLFFFFFRRLCLLGLALAAAALARRRLWRRRRRECCCGCCCCCCKCCCIVIIIDGIIIINECC--CCCCLCCRR 671

                          90
                  ....*....|
gi 1039737588 144 CLNLCCQPAC 153
Cdd:COG3901   672 CQDDPLCPPR 681
 
Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
106-152 1.22e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 46.22  E-value: 1.22e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1039737588 106 CCISSCCQPRCCISSCCQP-CCRPSCCQSSCCKPCCqpfCLNLCCQPA 152
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPsCCQPSCCQPSCCRPSC---CRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
104-139 6.91e-07

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 44.30  E-value: 6.91e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1039737588 104 PRCCISSCCQPRCCISSCCQP-CCRPSCCQSSCCKPC 139
Cdd:pfam13885   9 PSCCQPSCCQPSCCQPSCCQPsCCRPSCCRSSCCQPT 45
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 62-149 9.00e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 46.71  E-value: 9.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  62 QPCCVSSCCRTPCCQPCCCVSSCCQPCCQPSCCHCCQSSCCQ---PRCCISSCCQPRCCISSCCQP-----------CCR 127
Cdd:pfam01500  60 QPCCQTSCCQPTCCQTSSCQTGCGGIGYGQEGSSGAVSSRTRwcrPDCRVEGTCLPPCCVVSCTPPtccqlhhaqasCCR 139

                          90       100
                  ....*....|....*....|..
gi 1039737588 128 PSCCQSSCCKPCCQPFCLNLCC 149
Cdd:pfam01500 140 PSYCGQSCCRPACCCQCSEPTC 161
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 61-189 1.86e-06

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 45.94  E-value: 1.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  61 FQPCCVSSCCRTPCCQPCCCvssccqpccqpscchccQSSCCQPRCCISSCCQPRCCISSCCQPCCRPSCCQSSCCKPCC 140
Cdd:pfam01500  11 FPTCSTGGTCGSGCCQPCCC-----------------QSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQTSCCQPTCC 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039737588 141 QPFCLNLCC------QPACSGPVTCTRTCYQPTCVCVPGCLSQGCGSSCCEPCGC 189
Cdd:pfam01500  74 QTSSCQTGCggigygQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCC 128
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 62-189 7.08e-05

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 41.32  E-value: 7.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  62 QPCCVSSCCRTPCCQPCCCVSSCCQPCCQPSCCHCCQSSCcqprCCISSCCQPRCCISSCCQPCC-----------RPSC 130
Cdd:pfam01500  22 SGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQP----CCQTSCCQPTCCQTSSCQTGCggigygqegssGAVS 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039737588 131 CQSSCCKP--CCQPFCLNLCCQPACSGPvtctrTCYQPTCVCVPGCLSQGCGSSCCEPCGC 189
Cdd:pfam01500  98 SRTRWCRPdcRVEGTCLPPCCVVSCTPP-----TCCQLHHAQASCCRPSYCGQSCCRPACC 153
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
63-125 7.25e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 38.90  E-value: 7.25e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039737588  63 PCCVSSCCRTPCCQPCCCVssccqpccqpscchccqssccqPRCCISSCCQPRCCISSCCQPC 125
Cdd:pfam13885   5 SCCQPSCCQPSCCQPSCCQ----------------------PSCCQPSCCRPSCCRSSCCQPT 45
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
64-153 4.02e-04

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 40.30  E-value: 4.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039737588  64 CCVSSCCRTPCCQPCCCVSSCCQPCCQPSCCHCCQSSCCQPRCCISSCCQPRCCISSCCQPCCRPSCCQssCCKPCCQPF 143
Cdd:COG3901   594 LLLLLLLLFFFFFRRLCLLGLALAAAALARRRLWRRRRRECCCGCCCCCCKCCCIVIIIDGIIIINECC--CCCCLCCRR 671

                          90
                  ....*....|
gi 1039737588 144 CLNLCCQPAC 153
Cdd:COG3901   672 CQDDPLCPPR 681
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
125-187 1.96e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 35.05  E-value: 1.96e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039737588 125 CCRPSCCQSSCCKPCCqpfclnlcCQPACSGPVTCTRTCYQPTCvcvpgclsqgCGSSCCEPC 187
Cdd:pfam13885   1 CCQPSCCQPSCCQPSC--------CQPSCCQPSCCQPSCCRPSC----------CRSSCCQPT 45
NosR COG3901
Transcriptional regulator NosR of nitric oxide reductase [Transcription];
104-172 4.96e-03

Transcriptional regulator NosR of nitric oxide reductase [Transcription];


Pssm-ID: 443108 [Multi-domain]  Cd Length: 713  Bit Score: 36.84  E-value: 4.96e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039737588 104 PRCCISSCCQPRCCISSCCQPCCRPSCCQSSCCKPCCQPFCLNL------CCQPACsgpvTCTRTCYQPTCVCVP 172
Cdd:COG3901   611 LLGLALAAAALARRRLWRRRRRECCCGCCCCCCKCCCIVIIIDGiiiineCCCCCC----LCCRRCQDDPLCPPR 681
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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