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Conserved domains on  [gi|1034579226|ref|XP_016874706|]
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intraflagellar transport protein 81 homolog isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IFT81_CH pfam18383
Intraflagellar transport 81 calponin homology domain; This is the N-terminal domain found in ...
 3-126 3.48e-65

Intraflagellar transport 81 calponin homology domain; This is the N-terminal domain found in IFT81 proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity.


:

Pssm-ID: 465736  Cd Length: 124  Bit Score: 210.57  E-value: 3.48e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226   3 DQIKFIMDSLNKEPFRKNYNLITFDSLEPMQLLQVLSDVLAEIDPKQLVDIREEMPEQTAKRMLSLLGILKYKPSGNATD 82
Cdd:pfam18383   1 ENLKFIVTELNKEPFNKNYNLITFDSLSPEQLLQVLNDVLAEIDPKQKVDIREESPEETAIRILEALRILKYKPPPDIDD 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1034579226  83 MSTFRQGLVIGSKPVIYPVLHWLLQRTNELKKRAYLARFLIKLE 126
Cdd:pfam18383  81 PSAFRQGLVRGEKLVIYPILYWLLSNVEELKKRAYLARFLVKVE 124
PTZ00121 super family cl31754
MAEBL; Provisional
 138-672 3.63e-09

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 3.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  138 ADTNKQYEELMEAFKTLHKEYEQLKisgfsTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQwmLKIARQLRVEKE 217
Cdd:PTZ00121  1292 ADEAKKAEEKKKADEAKKKAEEAKK-----ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA--EAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  218 REEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPESLMKRLEEEIKfnlymVTEKFPKELENKKKELHFLQK 297
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK-----KADEAKKKAEEKKKADEAKKK 1439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  298 V--------VSEPAMGHSDLLELESKINEINT--EINQLIEKKMmRNEPIEGKLSLYRQQASIISRKKEAK--AEELQEA 365
Cdd:PTZ00121  1440 AeeakkadeAKKKAEEAKKAEEAKKKAEEAKKadEAKKKAEEAK-KADEAKKKAEEAKKKADEAKKAAEAKkkADEAKKA 1518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  366 KEKLASLE-REASVKRNQTREFDGTEVLKGDEFKRyVNKLRsKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQ 444
Cdd:PTZ00121  1519 EEAKKADEaKKAEEAKKADEAKKAEEKKKADELKK-AEELK-KAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE 1596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  445 QLQTMEEKKGISGYSYTQEELERVSA--LKSEVDEMKG--RTLDDMSEMVKKLYSLVSEKKSALASVIKELRQL---RQK 517
Cdd:PTZ00121  1597 VMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEKKKveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAeedKKK 1676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  518 YQELTQECDEKKSQYDSCAAGLESNRsKLEQEVRRLREECLQEESryhytncmIKNLEVQLRRATDEMKAYISSDQQEKR 597
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEE--------LKKAEEENKIKAEEAKKEAEEDKKKAE 1747

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034579226  598 KAIREQYTKNTAEQenLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKqcflKQQSQTSIGQVIQEGGED 672
Cdd:PTZ00121  1748 EAKKDEEEKKKIAH--LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK----KIKDIFDNFANIIEGGKE 1816
 
Name Accession Description Interval E-value
IFT81_CH pfam18383
Intraflagellar transport 81 calponin homology domain; This is the N-terminal domain found in ...
 3-126 3.48e-65

Intraflagellar transport 81 calponin homology domain; This is the N-terminal domain found in IFT81 proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity.


Pssm-ID: 465736  Cd Length: 124  Bit Score: 210.57  E-value: 3.48e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226   3 DQIKFIMDSLNKEPFRKNYNLITFDSLEPMQLLQVLSDVLAEIDPKQLVDIREEMPEQTAKRMLSLLGILKYKPSGNATD 82
Cdd:pfam18383   1 ENLKFIVTELNKEPFNKNYNLITFDSLSPEQLLQVLNDVLAEIDPKQKVDIREESPEETAIRILEALRILKYKPPPDIDD 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1034579226  83 MSTFRQGLVIGSKPVIYPVLHWLLQRTNELKKRAYLARFLIKLE 126
Cdd:pfam18383  81 PSAFRQGLVRGEKLVIYPILYWLLSNVEELKKRAYLARFLVKVE 124
PTZ00121 PTZ00121
MAEBL; Provisional
 138-672 3.63e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 3.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  138 ADTNKQYEELMEAFKTLHKEYEQLKisgfsTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQwmLKIARQLRVEKE 217
Cdd:PTZ00121  1292 ADEAKKAEEKKKADEAKKKAEEAKK-----ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA--EAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  218 REEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPESLMKRLEEEIKfnlymVTEKFPKELENKKKELHFLQK 297
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK-----KADEAKKKAEEKKKADEAKKK 1439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  298 V--------VSEPAMGHSDLLELESKINEINT--EINQLIEKKMmRNEPIEGKLSLYRQQASIISRKKEAK--AEELQEA 365
Cdd:PTZ00121  1440 AeeakkadeAKKKAEEAKKAEEAKKKAEEAKKadEAKKKAEEAK-KADEAKKKAEEAKKKADEAKKAAEAKkkADEAKKA 1518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  366 KEKLASLE-REASVKRNQTREFDGTEVLKGDEFKRyVNKLRsKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQ 444
Cdd:PTZ00121  1519 EEAKKADEaKKAEEAKKADEAKKAEEKKKADELKK-AEELK-KAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE 1596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  445 QLQTMEEKKGISGYSYTQEELERVSA--LKSEVDEMKG--RTLDDMSEMVKKLYSLVSEKKSALASVIKELRQL---RQK 517
Cdd:PTZ00121  1597 VMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEKKKveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAeedKKK 1676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  518 YQELTQECDEKKSQYDSCAAGLESNRsKLEQEVRRLREECLQEESryhytncmIKNLEVQLRRATDEMKAYISSDQQEKR 597
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEE--------LKKAEEENKIKAEEAKKEAEEDKKKAE 1747

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034579226  598 KAIREQYTKNTAEQenLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKqcflKQQSQTSIGQVIQEGGED 672
Cdd:PTZ00121  1748 EAKKDEEEKKKIAH--LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK----KIKDIFDNFANIIEGGKE 1816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 183-556 1.64e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 183 DQLIKRVEHLKKRVETAqnhqwmlkiarqlrvekerEEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAkpESL 262
Cdd:COG1196   196 GELERQLEPLERQAEKA-------------------ERYRELKEELKELEAELLLLKLRELEAELEELEAELEEL--EAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 263 MKRLEEEIkfnlymvtekfpKELENKKKELhflqkvvsepamgHSDLLELESKINEINTEINQLIEKKmmrnEPIEGKLS 342
Cdd:COG1196   255 LEELEAEL------------AELEAELEEL-------------RLELEELELELEEAQAEEYELLAEL----ARLEQDIA 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 343 LYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELK 422
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 423 AEFGLLQRTEELLKQRHENIQQQLQTMEEKKgISGYSYTQEELERVSALKSEVDEMKgRTLDDMSEMVKKLYSLVSEKKS 502
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERL-ERLEEELEELEEALAELEEEEEEEE-EALEEAAEEEAELEEEEEALLE 463

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034579226 503 ALASVIKELRQLRQKYQELTQECDEKKSQYDScAAGLESNRSKLEQEVRRLREE 556
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLL-LLEAEADYEGFLEGVKAALLL 516
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 283-556 1.34e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  283 KELENKKKEL----HFLQKVVSEPAMGHSDLLELESKINEINTEINQLI---EKKMMRNEPIEGKLSLYRQQASIISRKK 355
Cdd:TIGR02168  680 EELEEKIEELeekiAELEKALAELRKELEELEEELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  356 EAKAEELQEAKEKLASLEREASVKRNQTREfdgtevlKGDEFKRYVNKLRSKSTVFKKKHQiiaELKAEFGLLQRTEELL 435
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEA-------QIEQLKEELKALREALDELRAELT---LLNEEAANLRERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  436 KQRHENIQQQLQTMEEKKGIsgysyTQEELERVSA----LKSEVDEMKgRTLDDMSEMVKKLYSLVSEKKSALASVIKEL 511
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEE-----LSEDIESLAAeieeLEELIEELE-SELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1034579226  512 RQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREE 556
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 329-622 5.75e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 5.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 329 KKMMRNEPIEGKLSLYRQQASIISRKKEAKAEEL------QEAKEKLASLEREASVKRNQTR---EFDGTEVLKGD---- 395
Cdd:pfam17380 263 QTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMeqerlrQEKEEKAREVERRRKLEEAEKArqaEMDRQAAIYAEqerm 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 396 --EFKRYVNKLR---SKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEEKKgisgysyTQEElERVSA 470
Cdd:pfam17380 343 amERERELERIRqeeRKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVK-------ILEE-ERQRK 414

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 471 LKSEVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKE-------LRQLRQKYQELTQECDEKKSQYDSCAAGLESNR 543
Cdd:pfam17380 415 IQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEeqerqqqVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR 494

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 544 SKLEQEVRRLREECLQEESRYHYTNCMIKN-----LEVQLRRATDEMKAyiSSDQQEKRKAIREQYTKNTAEQENLGKKL 618
Cdd:pfam17380 495 KILEKELEERKQAMIEEERKRKLLEKEMEErqkaiYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEERSRLEAME 572


                  ....
gi 1034579226 619 REKQ 622
Cdd:pfam17380 573 RERE 576
 
Name Accession Description Interval E-value
IFT81_CH pfam18383
Intraflagellar transport 81 calponin homology domain; This is the N-terminal domain found in ...
 3-126 3.48e-65

Intraflagellar transport 81 calponin homology domain; This is the N-terminal domain found in IFT81 proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity.


Pssm-ID: 465736  Cd Length: 124  Bit Score: 210.57  E-value: 3.48e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226   3 DQIKFIMDSLNKEPFRKNYNLITFDSLEPMQLLQVLSDVLAEIDPKQLVDIREEMPEQTAKRMLSLLGILKYKPSGNATD 82
Cdd:pfam18383   1 ENLKFIVTELNKEPFNKNYNLITFDSLSPEQLLQVLNDVLAEIDPKQKVDIREESPEETAIRILEALRILKYKPPPDIDD 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1034579226  83 MSTFRQGLVIGSKPVIYPVLHWLLQRTNELKKRAYLARFLIKLE 126
Cdd:pfam18383  81 PSAFRQGLVRGEKLVIYPILYWLLSNVEELKKRAYLARFLVKVE 124
PTZ00121 PTZ00121
MAEBL; Provisional
 138-672 3.63e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 3.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  138 ADTNKQYEELMEAFKTLHKEYEQLKisgfsTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQwmLKIARQLRVEKE 217
Cdd:PTZ00121  1292 ADEAKKAEEKKKADEAKKKAEEAKK-----ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA--EAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  218 REEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPESLMKRLEEEIKfnlymVTEKFPKELENKKKELHFLQK 297
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK-----KADEAKKKAEEKKKADEAKKK 1439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  298 V--------VSEPAMGHSDLLELESKINEINT--EINQLIEKKMmRNEPIEGKLSLYRQQASIISRKKEAK--AEELQEA 365
Cdd:PTZ00121  1440 AeeakkadeAKKKAEEAKKAEEAKKKAEEAKKadEAKKKAEEAK-KADEAKKKAEEAKKKADEAKKAAEAKkkADEAKKA 1518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  366 KEKLASLE-REASVKRNQTREFDGTEVLKGDEFKRyVNKLRsKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQ 444
Cdd:PTZ00121  1519 EEAKKADEaKKAEEAKKADEAKKAEEKKKADELKK-AEELK-KAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE 1596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  445 QLQTMEEKKGISGYSYTQEELERVSA--LKSEVDEMKG--RTLDDMSEMVKKLYSLVSEKKSALASVIKELRQL---RQK 517
Cdd:PTZ00121  1597 VMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEKKKveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAeedKKK 1676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  518 YQELTQECDEKKSQYDSCAAGLESNRsKLEQEVRRLREECLQEESryhytncmIKNLEVQLRRATDEMKAYISSDQQEKR 597
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEE--------LKKAEEENKIKAEEAKKEAEEDKKKAE 1747

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034579226  598 KAIREQYTKNTAEQenLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKqcflKQQSQTSIGQVIQEGGED 672
Cdd:PTZ00121  1748 EAKKDEEEKKKIAH--LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK----KIKDIFDNFANIIEGGKE 1816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 183-556 1.64e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 183 DQLIKRVEHLKKRVETAqnhqwmlkiarqlrvekerEEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAkpESL 262
Cdd:COG1196   196 GELERQLEPLERQAEKA-------------------ERYRELKEELKELEAELLLLKLRELEAELEELEAELEEL--EAE 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 263 MKRLEEEIkfnlymvtekfpKELENKKKELhflqkvvsepamgHSDLLELESKINEINTEINQLIEKKmmrnEPIEGKLS 342
Cdd:COG1196   255 LEELEAEL------------AELEAELEEL-------------RLELEELELELEEAQAEEYELLAEL----ARLEQDIA 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 343 LYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELK 422
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 423 AEFGLLQRTEELLKQRHENIQQQLQTMEEKKgISGYSYTQEELERVSALKSEVDEMKgRTLDDMSEMVKKLYSLVSEKKS 502
Cdd:COG1196   386 EELLEALRAAAELAAQLEELEEAEEALLERL-ERLEEELEELEEALAELEEEEEEEE-EALEEAAEEEAELEEEEEALLE 463

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034579226 503 ALASVIKELRQLRQKYQELTQECDEKKSQYDScAAGLESNRSKLEQEVRRLREE 556
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLL-LLEAEADYEGFLEGVKAALLL 516
PTZ00121 PTZ00121
MAEBL; Provisional
 170-651 2.05e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.76  E-value: 2.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  170 EIRKdisAMEEEKDQLIKRVEHLKKRVETAQnhqwmlkiarqlRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKS 249
Cdd:PTZ00121  1216 EARK---AEDAKKAEAVKKAEEAKKDAEEAK------------KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  250 MRQAAADAKPESLMKRLEEEIKfnlymVTEKFPKELENKKKELHFLQKvvSEPAMGHSDLLELESKineintEINQLIEK 329
Cdd:PTZ00121  1281 DELKKAEEKKKADEAKKAEEKK-----KADEAKKKAEEAKKADEAKKK--AEEAKKKADAAKKKAE------EAKKAAEA 1347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  330 KMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLER-EASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKS 408
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAAAAKKKADEAKKKA 1427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  409 TVFKKKHqiiaELKAEFGLLQRTEELLKQRHE--NIQQQLQTMEEKKGISGYSYTQEELERVSALKSEVDEMKGRT--LD 484
Cdd:PTZ00121  1428 EEKKKAD----EAKKKAEEAKKADEAKKKAEEakKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAdeAK 1503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  485 DMSEMVKKLYSLvseKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSkleQEVRRLREECLQEESRY 564
Cdd:PTZ00121  1504 KAAEAKKKADEA---KKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA---EEKKKAEEAKKAEEDKN 1577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  565 HYTNCMIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQ 644
Cdd:PTZ00121  1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657


                   ....*..
gi 1034579226  645 LMECKKQ 651
Cdd:PTZ00121  1658 ENKIKAA 1664
PTZ00121 PTZ00121
MAEBL; Provisional
 107-610 4.84e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 4.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  107 QRTNELKKRAYLARFLIKLEVPSEflQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDisAMEEEKDQLI 186
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADEAKKKAE--EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE--AAEKKKEEAK 1377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  187 KRVEHLKKRVETAQNHQWMLKIARQLRveKEREEylAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPESLMKRL 266
Cdd:PTZ00121  1378 KKADAAKKKAEEKKKADEAKKKAEEDK--KKADE--LKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA 1453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  267 EEEIKfnlymvTEKFPKELENKKKELHFLQKvvsepAMGHSDLLELESKINEINTEINQLIEKKMMRNEPIEGKLSLYRQ 346
Cdd:PTZ00121  1454 EEAKK------AEEAKKKAEEAKKADEAKKK-----AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAK 1522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  347 QASIISRKKEA-KAEELQEAKEKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKA-E 424
Cdd:PTZ00121  1523 KADEAKKAEEAkKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLyE 1602

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  425 FGLLQRTEELLKQRHENIQ-QQLQTMEE--KKGISGYSYTQEELERVSALKSEVDEMK------GRTLDDMSEMVKKLYS 495
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKIKaEELKKAEEekKKVEQLKKKEAEEKKKAEELKKAEEENKikaaeeAKKAEEDKKKAEEAKK 1682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  496 LVSEKKSALASVIKE------LRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRlREECLQEESRYHYTNC 569
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEaeeakkAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK-AEEAKKDEEEKKKIAH 1761

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1034579226  570 MIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYTKNTAE 610
Cdd:PTZ00121  1762 LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 283-556 1.34e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  283 KELENKKKEL----HFLQKVVSEPAMGHSDLLELESKINEINTEINQLI---EKKMMRNEPIEGKLSLYRQQASIISRKK 355
Cdd:TIGR02168  680 EELEEKIEELeekiAELEKALAELRKELEELEEELEQLRKELEELSRQIsalRKDLARLEAEVEQLEERIAQLSKELTEL 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  356 EAKAEELQEAKEKLASLEREASVKRNQTREfdgtevlKGDEFKRYVNKLRSKSTVFKKKHQiiaELKAEFGLLQRTEELL 435
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEA-------QIEQLKEELKALREALDELRAELT---LLNEEAANLRERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  436 KQRHENIQQQLQTMEEKKGIsgysyTQEELERVSA----LKSEVDEMKgRTLDDMSEMVKKLYSLVSEKKSALASVIKEL 511
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEE-----LSEDIESLAAeieeLEELIEELE-SELEALLNERASLEEALALLRSELEELSEEL 903

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1034579226  512 RQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREE 556
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 142-457 3.10e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 3.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 142 KQYEELMEAFKTLHKEYEQLKIsgfstAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHqwmlkiARQLRVEKEREEY 221
Cdd:COG1196   213 ERYRELKEELKELEAELLLLKL-----RELEAELEELEAELEELEAELEELEAELAELEAE------LEELRLELEELEL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 222 LAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKpeslmKRLEEEIKfNLYMVTEKFPKELENKKKELHFLQKVVSE 301
Cdd:COG1196   282 ELEEAQAEEYELLAELARLEQDIARLEERRRELEERL-----EELEEELA-ELEEELEELEEELEELEEELEEAEEELEE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 302 PAMGHSD----LLELESKINEINTEINQLIEKKMM---RNEPIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLER 374
Cdd:COG1196   356 AEAELAEaeeaLLEAEAELAEAEEELEELAEELLEalrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 375 EASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEEKKG 454
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515


                  ...
gi 1034579226 455 ISG 457
Cdd:COG1196   516 LAG 518
PRK12704 PRK12704
phosphodiesterase; Provisional
 337-492 3.18e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 50.16  E-value: 3.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 337 IEGKLSLYRQQASIISRKKEAKAEELQeaKEKLASLEREASvkrNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQ 416
Cdd:PRK12704   29 AEAKIKEAEEEAKRILEEAKKEAEAIK--KEALLEAKEEIH---KLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLE 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 417 IIAELKAEfglLQRTEELLKQRHENIQQQLQTMEEKkgisgYSYTQEELERVSALKSE------VDEMKGRTLDDMSEMV 490
Cdd:PRK12704  104 LLEKREEE---LEKKEKELEQKQQELEKKEEELEEL-----IEEQLQELERISGLTAEeakeilLEKVEEEARHEAAVLI 175


                  ..
gi 1034579226 491 KK 492
Cdd:PRK12704  176 KE 177
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 224-555 6.34e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 6.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  224 QQKQEQKNQLFHAVQRLQRVQN-------QLKSMRQAAADAKPESLMKRLEEEIKFNLYMvtekfpKELENKKKELHFLQ 296
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDilnelerQLKSLERQAEKAERYKELKAELRELELALLV------LRLEELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  297 KVVSEPAmghSDLLELESKINEINTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEakaeELQEAKEKLASLEREA 376
Cdd:TIGR02168  246 EELKEAE---EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ----QKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  377 SVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHEN--------------I 442
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETlrskvaqlelqiasL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  443 QQQLQTMEEKKGISGYSyTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELT 522
Cdd:TIGR02168  399 NNEIERLEARLERLEDR-RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1034579226  523 QECDEKKSQYDSCAAGLESNRSKLEQEVRRLRE 555
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKA 510
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
168-382 1.30e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 1.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 168 TAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQL 247
Cdd:COG3206   170 REEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 248 KSMRQAAADAKPESLMKRLEEEIkfnlymvtekfpKELENKKKELhfLQKVVSEpamgHSDLLELESKINEINTEINQLI 327
Cdd:COG3206   250 GSGPDALPELLQSPVIQQLRAQL------------AELEAELAEL--SARYTPN----HPDVIALRAQIAALRAQLQQEA 311

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034579226 328 EKKM--MRNEpiegKLSLYRQQASIISRKKEAKAE--ELQEAKEKLASLEREASVKRNQ 382
Cdd:COG3206   312 QRILasLEAE----LEALQAREASLQAQLAQLEARlaELPELEAELRRLEREVEVAREL 366
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 353-622 2.12e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 2.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  353 RKKEAKAEELQEAKEKLASLEREASVKRNQtREFDGTEVLKGDEFK---------RYVNKLRSKSTVFKKKHQIIAELKA 423
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQ-LERLRREREKAERYQallkekreyEGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  424 EFGLLQRTEELLKQRHENIQQQLQTMEE------KKGISGYSYTQEELERVSALKSEVD---EMKGRTLDDMSEMVKKLY 494
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEElnkkikDLGEEEQLRVKEKIGELEAEIASLErsiAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  495 SLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESnrskLEQEVRRLREECLQEESRYHYTNCMIKNL 574
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE----VDKEFAETRDELKDYREKLEKLKREINEL 404

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034579226  575 EVQLRRATDEMKAYIS--SDQQEKRKAIREQYTKNTAEQENLGKKLREKQ 622
Cdd:TIGR02169  405 KRELDRLQEELQRLSEelADLNAAIAGIEAKINELEEEKEDKALEIKKQE 454
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
159-627 2.24e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 2.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 159 EQLKISGFSTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQWML----KIARQLRVEKEREEYLAQQKQEQKNQLF 234
Cdd:PRK03918  193 ELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIeeleKELESLEGSKRKLEEKIRELEERIEELK 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 235 HAVQRLQRVQNQLKSMRQaaaDAKPESLMKRLEEEIKFNLYmvteKFPKELENKKKELHFLQKVVSEPAMGHSDLLELES 314
Cdd:PRK03918  273 KEIEELEEKVKELKELKE---KAEEYIKLSEFYEEYLDELR----EIEKRLSRLEEEINGIEERIKELEEKEERLEELKK 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 315 KINEINTEINQLIEK---------KMMRNEPIEGKLSLY-----RQQASIISRKKEAKAEELQEAKEKLASLEREASVKR 380
Cdd:PRK03918  346 KLKELEKRLEELEERhelyeeakaKKEELERLKKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELK 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 381 NQTREFDG------------TEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEF----GLLQRTEELLKQRheNIQQ 444
Cdd:PRK03918  426 KAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELreleKVLKKESELIKLK--ELAE 503

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 445 QLQTMEEKKGISGYSYTQEELERVSALKSEVDEMKG------RTLDDMSEMVKKLYSLVSEKKSA---LASVIKELRQLR 515
Cdd:PRK03918  504 QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGeikslkKELEKLEELKKKLAELEKKLDELeeeLAELLKELEELG 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 516 QK-YQELTQECDEKKSQYDSCAAGLESnrsklEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQQ 594
Cdd:PRK03918  584 FEsVEELEERLKELEPFYNEYLELKDA-----EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE 658

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1034579226 595 EKRKAIREQYTKNTAEQENLGKKLREKQKVIRE 627
Cdd:PRK03918  659 EEYEELREEYLELSRELAGLRAELEELEKRREE 691
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 354-563 2.43e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 2.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 354 KKEAKAEELQEAKEKLASLEREASVKRNQtrefdgtevlkgdefkryVNKLRSKSTVFKKKhqiIAELKAEfglLQRTEE 433
Cdd:COG3883    24 ELSELQAELEAAQAELDALQAELEELNEE------------------YNELQAELEALQAE---IDKLQAE---IAEAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 434 LLKQRHENIQQQLQTMEEKKGISGY-------SYTQEELERVSALKSEVDEMKgRTLDDMSEMVKKLyslvSEKKSALAS 506
Cdd:COG3883    80 EIEERREELGERARALYRSGGSVSYldvllgsESFSDFLDRLSALSKIADADA-DLLEELKADKAEL----EAKKAELEA 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034579226 507 VIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESR 563
Cdd:COG3883   155 KLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
mukB PRK04863
chromosome partition protein MukB;
359-627 7.52e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 7.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  359 AEELQEAKEKLASLEREASVKRNQTREfdgtevlkgdefkryvnkLRSKSTVFKKKHQIIAELKAEFGLLQrtEELLKQR 438
Cdd:PRK04863   836 EAELRQLNRRRVELERALADHESQEQQ------------------QRSQLEQAKEGLSALNRLLPRLNLLA--DETLADR 895

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  439 HENIQQQLQTMEE-KKGISGYSYTQEELER-VSALKSevDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKEL----- 511
Cdd:PRK04863   896 VEEIREQLDEAEEaKRFVQQHGNALAQLEPiVSVLQS--DPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRahfsy 973

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  512 --------------RQLRQKYQELTQECDEKK----------SQYDSCAAGLESNRSKLEQEVRRLREEClqEESRYHYT 567
Cdd:PRK04863   974 edaaemlaknsdlnEKLRQRLEQAEQERTRAReqlrqaqaqlAQYNQVLASLKSSYDAKRQMLQELKQEL--QDLGVPAD 1051

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  568 ncmiKNLEVQLRRATDEMKAYISSdQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRE 627
Cdd:PRK04863  1052 ----SGAEERARARRDELHARLSA-NRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHE 1106
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
179-628 9.56e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 9.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 179 EEEKDQLIKRVEHLKKRVETAQNhqwMLKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAAD-- 256
Cdd:PRK03918  144 DESREKVVRQILGLDDYENAYKN---LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPElr 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 257 AKPESLMKRLEEeikfnlymvTEKFPKELENKKKELHFLQKVVSEPamgHSDLLELESKINEINTEINQLiEKKMMRNEP 336
Cdd:PRK03918  221 EELEKLEKEVKE---------LEELKEEIEELEKELESLEGSKRKL---EEKIRELEERIEELKKEIEEL-EEKVKELKE 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 337 IEGKLSLYRqqasIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREFDgtevlkgdefkryvnklrskstvfkKKHQ 416
Cdd:PRK03918  288 LKEKAEEYI----KLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE-------------------------EKEE 338

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 417 IIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEEKKGISGySYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSL 496
Cdd:PRK03918  339 RLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKK-RLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGEL 417

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 497 VSEKKSaLASVIKELRQLRQKY----QELTQECDEK-KSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMI 571
Cdd:PRK03918  418 KKEIKE-LKKAIEELKKAKGKCpvcgRELTEEHRKElLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034579226 572 KNLEV--QLRRATDEMKAYISSDQQEKRK---AIREQYTKNTAEQENLGKKLREKQKVIRES 628
Cdd:PRK03918  497 KLKELaeQLKELEEKLKKYNLEELEKKAEeyeKLKEKLIKLKGEIKSLKKELEKLEELKKKL 558
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-612 1.79e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 337 IEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQ 416
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 417 IIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEEKKGISgysytQEELERVSALKSEVDEMKGRTLDDMSEMVKKLysl 496
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA-----EAELAEAEEALLEAEAELAEAEEELEELAEEL--- 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 497 vSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREEclQEESRYHYTNcmIKNLEV 576
Cdd:COG1196   389 -LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA--AEEEAELEEE--EEALLE 463

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1034579226 577 QLRRATDEMKAYISSDQQEKRKAIREQYTKNTAEQE 612
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
311-534 2.24e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 311 ELESKINEINTEINQLIEKKMMRNepIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREFDGTE 390
Cdd:COG3206   186 ELRKELEEAEAALEEFRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSP 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 391 VLKG--DEFKRYVNKLRSKSTVFKKKHQIIAELKAEfglLQRTEELLKQRHENIQQQLQTMeekkgisgysyTQEELERV 468
Cdd:COG3206   264 VIQQlrAQLAELEAELAELSARYTPNHPDVIALRAQ---IAALRAQLQQEAQRILASLEAE-----------LEALQARE 329

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034579226 469 SALKSEVDEMKGRtlddmsemvkklyslvsekksalasvIKELRQLRQKYQELTQECDEKKSQYDS 534
Cdd:COG3206   330 ASLQAQLAQLEAR--------------------------LAELPELEAELRRLEREVEVARELYES 369
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 145-551 2.58e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 2.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  145 EELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLIKrvehlkkrvetaqnhqwmlkiARQLRVEKEREEYLAQ 224
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER---------------------YQALLKEKREYEGYEL 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  225 QKQEQKnqlfhAVQRLQRVQNQLKSmrqaaadakpeslmkrLEEEIkfnlymvtEKFPKELENKKKELHflqkvvsepam 304
Cdd:TIGR02169  229 LKEKEA-----LERQKEAIERQLAS----------------LEEEL--------EKLTEEISELEKRLE----------- 268

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  305 ghsdllELESKINEINTEINQLIEKKMMRnepIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTR 384
Cdd:TIGR02169  269 ------EIEQLLEELNKKIKDLGEEEQLR---VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  385 EFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFGLL--------QRTEELLKQRHENIQQQLQTMEEKKGIS 456
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETrdelkdyrEKLEKLKREINELKRELDRLQEELQRLS 419

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  457 G-YSYTQEELERVSALKSEVDEmkgrTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSc 535
Cdd:TIGR02169  420 EeLADLNAAIAGIEAKINELEE----EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE- 494

                          410
                   ....*....|....*.
gi 1034579226  536 aagLESNRSKLEQEVR 551
Cdd:TIGR02169  495 ---AEAQARASEERVR 507
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 134-395 4.19e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 4.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  134 DETVADTNKQYEELMEAFKTLHKEYEQLkiSGFSTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQWMLKIAR-QL 212
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDL--GEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIdKL 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  213 RVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQ---AAADAKPESLMKRLEEeikfnLYMVTEKFPKELENKK 289
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEevdKEFAETRDELKDYREK-----LEKLKREINELKRELD 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  290 KELHFLQKVVSEPAMGHSDLLELESKINEINTEINQL---IEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQEAK 366
Cdd:TIGR02169  410 RLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          250       260
                   ....*....|....*....|....*....
gi 1034579226  367 EKLASLEREASVKRNQTREFDGTEVLKGD 395
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEEVLKA 518
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 311-587 4.34e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 4.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  311 ELESKINEINtEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLERE-----ASVKRNQTRE 385
Cdd:TIGR02169  689 ELSSLQSELR-RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEienvkSELKELEARI 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  386 FDGTEVL--------------KGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEE 451
Cdd:TIGR02169  768 EELEEDLhkleealndlearlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  452 KKgiSGYSYTQEELE-RVSALKSEVDEMKGRtLDDMSEMVKKLYSLVSEkksalasVIKELRQLRQKYQELTQECDEKKS 530
Cdd:TIGR02169  848 QI--KSIEKEIENLNgKKEELEEELEELEAA-LRDLESRLGDLKKERDE-------LEAQLRELERKIEELEAQIEKKRK 917

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034579226  531 QydscAAGLESNRSKLEQEVRRLrEECLQEESRYHYTNCMIKNLEVQLRRATDEMKA 587
Cdd:TIGR02169  918 R----LSELKAKLEALEEELSEI-EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
PTZ00121 PTZ00121
MAEBL; Provisional
 179-644 6.50e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 6.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  179 EEEKDQLIKRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQEQKNqlfhaVQRLQRVQNQLK-SMRQAAADA 257
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKR-----VEIARKAEDARKaEEARKAEDA 1175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  258 KPESLMKRLEEEIKFNLYMVTEKFPKELENKKKElhflQKVVSEPAMGHSDLLELES--KINEINTEINQLIEKKMMRNE 335
Cdd:PTZ00121  1176 KKAEAARKAEEVRKAEELRKAEDARKAEAARKAE----EERKAEEARKAEDAKKAEAvkKAEEAKKDAEEAKKAEEERNN 1251

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  336 P-----IEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREF--DGTEVLKGDEFKRYVNKLRSKS 408
Cdd:PTZ00121  1252 EeirkfEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAkkKAEEAKKADEAKKKAEEAKKKA 1331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  409 TVFKKKHQiIAELKAEFGLLQ---RTEELLKQRHENIQQQLQTMEEKKGISGYSYTQEELERVSALKSEVDEMKGRTLDD 485
Cdd:PTZ00121  1332 DAAKKKAE-EAKKAAEAAKAEaeaAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL 1410

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  486 MSEMVKKLYSLVSEKKSALASVIKELR---QLRQKYQELTQECDEKKSQYDSCAAGLESNRSkleQEVRRLREECLQEES 562
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKkkaEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA---DEAKKKAEEAKKADE 1487

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  563 RYHYTNCMIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYTKNTAEQENLgKKLREKQKVIRESHGPNMKQAKMWRDL 642
Cdd:PTZ00121  1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA-KKAEEKKKADELKKAEELKKAEEKKKA 1566


                   ..
gi 1034579226  643 EQ 644
Cdd:PTZ00121  1567 EE 1568
COG5022 COG5022
Myosin heavy chain [General function prediction only];
206-455 8.64e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.76  E-value: 8.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  206 LKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAAD----AKPESLMKRLEEEIKFNLYMVTEKf 281
Cdd:COG5022    797 IKLQPLLSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLiqkfGRSLKAKKRFSLLKKETIYLQSAQ- 875

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  282 pkELENKKKELHFLQKVVSEPAMGHSDLLELESKIneinTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEE 361
Cdd:COG5022    876 --RVELAERQLQELKIDVKSISSLKLVNLELESEI----IELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIE 949

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  362 LQEaKEKLASLEREASVKRNQTREFdGTEVLKGDEFKRYVNKLRSKStvfKKKHQIIAELKAEFGLLQRTEELLKQR--- 438
Cdd:COG5022    950 YVK-LPELNKLHEVESKLKETSEEY-EDLLKKSTILVREGNKANSEL---KNFKKELAELSKQYGALQESTKQLKELpve 1024

                          250       260
                   ....*....|....*....|
gi 1034579226  439 ---HENIQQQLQTMEEKKGI 455
Cdd:COG5022   1025 vaeLQSASKIISSESTELSI 1044
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 170-671 1.33e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  170 EIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQwmLKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKS 249
Cdd:TIGR00618  376 TLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQ--ATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQC 453

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  250 MRQAAADAKPeslMKRLEEEIKFNLYMVTEKFPKELENKKKELHFLQKVVSEPAMGHSDLLELESK-----INEINTEIN 324
Cdd:TIGR00618  454 EKLEKIHLQE---SAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPArqdidNPGPLTRRM 530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  325 QLIEKKMMRNEPIEGKLslYRQQASIISRKK--EAKAEELQEAKEKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVN 402
Cdd:TIGR00618  531 QRGEQTYAQLETSEEDV--YHQLTSERKQRAslKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED 608

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  403 KLRSKSTVFKKKHQIIAELKAefgllqrteelLKQRHENIQQQLQTMEEKKGISGYSYTQEELERVSALKSEVDEMKGRT 482
Cdd:TIGR00618  609 MLACEQHALLRKLQPEQDLQD-----------VRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLAS 677

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  483 LDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQ---EVRRLREECLQ 559
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQslkELMHQARTVLK 757

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  560 EESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQQE---------KRKAIREQYTKN-----TAEQENLGKKLREKQKVI 625
Cdd:TIGR00618  758 ARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLreedthllkTLEAEIGQEIPSdedilNLQCETLVQEEEQFLSRL 837

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1034579226  626 RESHgpnMKQAKMWRDLEQLMECKKQcflKQQSQTSIGQVIQEGGE 671
Cdd:TIGR00618  838 EEKS---ATLGEITHQLLKYEECSKQ---LAQLTQEQAKIIQLSDK 877
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 134-374 1.68e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  134 DETVADTNKQYEELMEAFKTLHKEYEQLkisgfstaeiRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQWMLKiARQLR 213
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEEL----------RLEVSELEEEIEELQKELYALANEISRLEQQKQILR-ERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  214 VEKEREEYLAQ-----QKQEQKNQLFHAVQ-RLQRVQNQLKSMRQAAADAKP-----ESLMKRLEEEIK------FNLYM 276
Cdd:TIGR02168  314 LERQLEELEAQleeleSKLDELAEELAELEeKLEELKEELESLEAELEELEAeleelESRLEELEEQLEtlrskvAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  277 VTEKFPKELENKKKELHFLQKVVS---------EPAMGHSDLLELESKINEINTEINQLIEkkmmRNEPIEGKLSLYRQQ 347
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRErlqqeieelLKKLEEAELKELQAELEELEEELEELQE----ELERLEEALEELREE 469

                          250       260
                   ....*....|....*....|....*..
gi 1034579226  348 ASIISRKKEAKAEELQEAKEKLASLER 374
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLER 496
PRK12704 PRK12704
phosphodiesterase; Provisional
 351-528 3.46e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.53  E-value: 3.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 351 ISRKKEAKAEElqEAKEKLASLEREAsvkrnqtrefdgtEVLKGDEfkryvnKLRSKSTVFKKKHQIIAELKAEFGLLQR 430
Cdd:PRK12704   28 IAEAKIKEAEE--EAKRILEEAKKEA-------------EAIKKEA------LLEAKEEIHKLRNEFEKELRERRNELQK 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 431 TEELLKQRHENIQQQLQTMEEKKgisgySYTQEELERVSALKSEVDEMKgRTLDDM-SEMVKKLYS---LVSE--KKSAL 504
Cdd:PRK12704   87 LEKRLLQKEENLDRKLELLEKRE-----EELEKKEKELEQKQQELEKKE-EELEELiEEQLQELERisgLTAEeaKEILL 160

                         170       180
                  ....*....|....*....|....*....
gi 1034579226 505 ASVIKELRQ-----LRQKYQELTQECDEK 528
Cdd:PRK12704  161 EKVEEEARHeaavlIKEIEEEAKEEADKK 189
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
133-621 4.06e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 40.41  E-value: 4.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 133 QDETVADTNKQYEELMEAFKTLHKEYEQLKISgfsTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNH------QWML 206
Cdd:PRK02224  228 QREQARETRDEADEVLEEHEERREELETLEAE---IEDLRETIAETEREREELAEEVRDLRERLEELEEErddllaEAGL 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 207 KIARQLRVEKEREEyLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADakpeslmkrLEEEikfnlymvtekfPKELE 286
Cdd:PRK02224  305 DDADAEAVEARREE-LEDRDEELRDRLEECRVAAQAHNEEAESLREDADD---------LEER------------AEELR 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 287 NKKKELHflqkvvSEPAMGHSDLLELESKINEINTEINQLIEKkmMRNEPIE-GKLSLYRqqasiisrkkEAKAEELQEA 365
Cdd:PRK02224  363 EEAAELE------SELEEAREAVEDRREEIEELEEEIEELRER--FGDAPVDlGNAEDFL----------EELREERDEL 424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 366 KEKLASLEREASVKRNQTREfdGTEVL---KGDEFKRYVNKLRSKSTVFKKKHQiIAELKAEFGLLQRTEELLKQRHENI 442
Cdd:PRK02224  425 REREAELEATLRTARERVEE--AEALLeagKCPECGQPVEGSPHVETIEEDRER-VEELEAELEDLEEEVEEVEERLERA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 443 QQ------QLQTMEEKKGISGYSYTQEElERVSALKSEVDEMKGRTLDDMSEMVKKLYSlVSEKKSALASVIKELRQLRQ 516
Cdd:PRK02224  502 EDlveaedRIERLEERREDLEELIAERR-ETIEEKRERAEELRERAAELEAEAEEKREA-AAEAEEEAEEAREEVAELNS 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 517 KYQELTQECD------EKKSQYDSCAAGLESNRSKLEQ--EVRRLREECLQEESRYHYtncmiknlevQLRRATDEmkAY 588
Cdd:PRK02224  580 KLAELKERIEslerirTLLAAIADAEDEIERLREKREAlaELNDERRERLAEKRERKR----------ELEAEFDE--AR 647

                         490       500       510
                  ....*....|....*....|....*....|...
gi 1034579226 589 ISSDQQEKRKAirEQYtkntaeQENLGKKLREK 621
Cdd:PRK02224  648 IEEAREDKERA--EEY------LEQVEEKLDEL 672
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 329-622 5.75e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.11  E-value: 5.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 329 KKMMRNEPIEGKLSLYRQQASIISRKKEAKAEEL------QEAKEKLASLEREASVKRNQTR---EFDGTEVLKGD---- 395
Cdd:pfam17380 263 QTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMeqerlrQEKEEKAREVERRRKLEEAEKArqaEMDRQAAIYAEqerm 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 396 --EFKRYVNKLR---SKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEEKKgisgysyTQEElERVSA 470
Cdd:pfam17380 343 amERERELERIRqeeRKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVK-------ILEE-ERQRK 414

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 471 LKSEVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKE-------LRQLRQKYQELTQECDEKKSQYDSCAAGLESNR 543
Cdd:pfam17380 415 IQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEeqerqqqVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR 494

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 544 SKLEQEVRRLREECLQEESRYHYTNCMIKN-----LEVQLRRATDEMKAyiSSDQQEKRKAIREQYTKNTAEQENLGKKL 618
Cdd:pfam17380 495 KILEKELEERKQAMIEEERKRKLLEKEMEErqkaiYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEERSRLEAME 572


                  ....
gi 1034579226 619 REKQ 622
Cdd:pfam17380 573 RERE 576
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 422-647 5.88e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 5.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  422 KAEFGLLQRTEELLKQRHENIQQQLQTMEEKKGISGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKL-------- 493
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLeaeveqle 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  494 --YSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMI 571
Cdd:TIGR02168  747 erIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226  572 KNLEVQLRRATDEMKayissDQQEKRKAIREQYTKNTAEQENLGKKLREKQK------VIRESHGPNMKQAKmwRDLEQL 645
Cdd:TIGR02168  827 ESLERRIAATERRLE-----DLEEQIEELSEDIESLAAEIEELEELIEELESeleallNERASLEEALALLR--SELEEL 899


                   ..
gi 1034579226  646 ME 647
Cdd:TIGR02168  900 SE 901
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 169-293 8.06e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 39.42  E-value: 8.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 169 AEIRKDISAMEEEKDQLIKRVEHLKKRVETAqnhqwmLKIARQLR--VEKEREEyLAQQKQEQKNQLFHAVQRL-QRVQN 245
Cdd:PRK00409  505 EEAKKLIGEDKEKLNELIASLEELERELEQK------AEEAEALLkeAEKLKEE-LEEKKEKLQEEEDKLLEEAeKEAQQ 577

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1034579226 246 QLKSMRQAAADakpesLMKRLEEEIKFNLYMVTEkfpKELENKKKELH 293
Cdd:PRK00409  578 AIKEAKKEADE-----IIKELRQLQKGGYASVKA---HELIEARKRLN 617
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
169-632 9.44e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 39.25  E-value: 9.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 169 AEIRKDISAMEEEKDQLIKRVEHLKKRVET-AQNHQWMLKIARQLR--------VEKEREEyLAQQKQEQKnqlfhavQR 239
Cdd:PRK02224  216 AELDEEIERYEEQREQARETRDEADEVLEEhEERREELETLEAEIEdlretiaeTEREREE-LAEEVRDLR-------ER 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 240 LQRVQNQLKSMRQAAA--DAKPESLMKRLEeeikfnlymvtekfpkELENKKKELhflqkvvsepamgHSDLLELESKIN 317
Cdd:PRK02224  288 LEELEEERDDLLAEAGldDADAEAVEARRE----------------ELEDRDEEL-------------RDRLEECRVAAQ 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 318 EINTEINQLIEKKMMRNEPIEGKlslyRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQtreFDGTEVLKGDEF 397
Cdd:PRK02224  339 AHNEEAESLREDADDLEERAEEL----REEAAELESELEEAREAVEDRREEIEELEEEIEELRER---FGDAPVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 398 KRYVNKLRSKSTVFKKKHQIIAELKAEFGLLQRTEELLKQ-RHENIQQQLQTMEEKKGISGYSYTQEELE-RVSALKSEV 475
Cdd:PRK02224  412 DFLEELREERDELREREAELEATLRTARERVEEAEALLEAgKCPECGQPVEGSPHVETIEEDRERVEELEaELEDLEEEV 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 476 DEMKGR--TLDDMSEMVKKLYSLvSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRL 553
Cdd:PRK02224  492 EEVEERleRAEDLVEAEDRIERL-EERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEA 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034579226 554 REECLQEESRYHYTNCMIKNLEvQLRRATDEMKAYIS--SDQQEKRKAIREqytKNTAEQENLGKKlREKQKVIRESHGP 631
Cdd:PRK02224  571 REEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDeiERLREKREALAE---LNDERRERLAEK-RERKRELEAEFDE 645


                  .
gi 1034579226 632 N 632
Cdd:PRK02224  646 A 646
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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