|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
509-622 |
6.30e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
:
Pssm-ID: 461796 Cd Length: 115 Bit Score: 111.90 E-value: 6.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 509 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 587
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1034559302 588 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 622
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
750-806 |
7.33e-16 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 72.49 E-value: 7.33e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 750 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 806
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
937-993 |
2.56e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 65.55 E-value: 2.56e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 937 WYTGPWGECSSECGSGTQRRDIICVSKLGteFNVTSPSNCSHLPRPPALQPCQGQAC 993
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
997-1048 |
4.63e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 59.00 E-value: 4.63e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1034559302 997 WFSTPWSPCSRSCQGGTQTREVQCLSTN---QTLSTRCPPQLRPSRKRPCNSQPC 1048
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGggsIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PLAC |
pfam08686 |
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ... |
1056-1085 |
8.36e-11 |
|
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.
:
Pssm-ID: 462560 Cd Length: 31 Bit Score: 57.55 E-value: 8.36e-11
10 20 30
....*....|....*....|....*....|
gi 1034559302 1056 CKDSSPHCPLVVQARLCVYPYYTATCCRSC 1085
Cdd:pfam08686 1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
|
|
| ADAMTS_CR_3 super family |
cl41950 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
436-507 |
7.89e-10 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
The actual alignment was detected with superfamily member pfam19236:
Pssm-ID: 437068 Cd Length: 115 Bit Score: 57.41 E-value: 7.89e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559302 436 QGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTC 507
Cdd:pfam19236 38 QGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
809-864 |
3.26e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 53.61 E-value: 3.26e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 809 WEVGsPWSQCSVRCGRGQRSRQVRCVG-NNGDEVSEQECaSGPPQPPSREACDMGPC 864
Cdd:pfam19030 1 WVAG-PWGECSVTCGGGVQTRLVQCVQkGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
868-931 |
8.43e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 49.76 E-value: 8.43e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034559302 868 WFHSDWSSkCSAECGTGIQRRSVVCLGSGaalgpGQGEAGagtGQSCPTGSRPPDMRACSLGPC 931
Cdd:pfam19030 1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKG-----GGSIVP---DSECSAQKKPPETQSCNLKPC 55
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
143-392 |
5.29e-06 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.09 E-value: 5.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 143 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 219
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 220 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 290
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 291 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 365
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809
|
250 260
....*....|....*....|....*....
gi 1034559302 366 GESEQLRA--CSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
47-77 |
8.99e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
:
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 8.99e-05
10 20 30
....*....|....*....|....*....|.
gi 1034559302 47 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
697-746 |
3.39e-03 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 36.66 E-value: 3.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1034559302 697 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 746
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
509-622 |
6.30e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 111.90 E-value: 6.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 509 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 587
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1034559302 588 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 622
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
750-806 |
7.33e-16 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 72.49 E-value: 7.33e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 750 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 806
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
937-993 |
2.56e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 65.55 E-value: 2.56e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 937 WYTGPWGECSSECGSGTQRRDIICVSKLGteFNVTSPSNCSHLPRPPALQPCQGQAC 993
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
997-1048 |
4.63e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 59.00 E-value: 4.63e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1034559302 997 WFSTPWSPCSRSCQGGTQTREVQCLSTN---QTLSTRCPPQLRPSRKRPCNSQPC 1048
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGggsIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PLAC |
pfam08686 |
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ... |
1056-1085 |
8.36e-11 |
|
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.
Pssm-ID: 462560 Cd Length: 31 Bit Score: 57.55 E-value: 8.36e-11
10 20 30
....*....|....*....|....*....|
gi 1034559302 1056 CKDSSPHCPLVVQARLCVYPYYTATCCRSC 1085
Cdd:pfam08686 1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
436-507 |
7.89e-10 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 57.41 E-value: 7.89e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559302 436 QGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTC 507
Cdd:pfam19236 38 QGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
809-864 |
3.26e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 53.61 E-value: 3.26e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 809 WEVGsPWSQCSVRCGRGQRSRQVRCVG-NNGDEVSEQECaSGPPQPPSREACDMGPC 864
Cdd:pfam19030 1 WVAG-PWGECSVTCGGGVQTRLVQCVQkGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
868-931 |
8.43e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 49.76 E-value: 8.43e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034559302 868 WFHSDWSSkCSAECGTGIQRRSVVCLGSGaalgpGQGEAGagtGQSCPTGSRPPDMRACSLGPC 931
Cdd:pfam19030 1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKG-----GGSIVP---DSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1000-1049 |
4.19e-06 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 44.89 E-value: 4.19e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1034559302 1000 TPWSPCSRSCQGGTQTREVQCLSTNQTLS-TRCPPQLRpsRKRPCNSQPCS 1049
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCSPPPQNGgGPCTGEDV--ETRACNEQPCP 53
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
143-392 |
5.29e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.09 E-value: 5.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 143 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 219
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 220 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 290
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 291 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 365
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809
|
250 260
....*....|....*....|....*....
gi 1034559302 366 GESEQLRA--CSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
809-864 |
3.11e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.57 E-value: 3.11e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559302 809 WEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDeVSEQECasgPPQPPSREACDMGPC 864
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPC---TGEDVETRACNEQPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
47-77 |
8.99e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 8.99e-05
10 20 30
....*....|....*....|....*....|.
gi 1034559302 47 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
99-316 |
5.88e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.87 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 99 GQGPRPQTSPETLPLYRTQSRGRGGPLRGPAShlgreeTQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 178
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMS------LEEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 179 PRSElslissrgeeaiPSPTPRAEPFSANGSPQTELPPTELSvHTPSPQAEPLSPetaqtevAPRTRPAPLRHHPRAQas 258
Cdd:pfam09770 238 PQIQ------------QQQQPQQQPQQPQQHPGQGHPVTILQ-RPQSPQPDPAQP-------SIQPQAQQFHQQPPPV-- 295
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559302 259 gtePPSPTHSLgeggffrasPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGP 316
Cdd:pfam09770 296 ---PVQPTQIL---------QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
|
|
| PTZ00441 |
PTZ00441 |
sporozoite surface protein 2 (SSP2); Provisional |
806-853 |
2.41e-03 |
|
sporozoite surface protein 2 (SSP2); Provisional
Pssm-ID: 240420 [Multi-domain] Cd Length: 576 Bit Score: 41.87 E-value: 2.41e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1034559302 806 CGHWEvgsPWSQCSVRCGRGQRSRQ-----VRCVGNNGDEVSEQECasgPPQP 853
Cdd:PTZ00441 240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEEC---PVEP 286
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
697-746 |
3.39e-03 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 36.66 E-value: 3.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1034559302 697 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 746
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
750-806 |
6.46e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 36.03 E-value: 6.46e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 750 WEAGEWTSCSRSCGPGTQHRQLQCRqefgGGGSSVPPERCGHLPRpnITQSCQLRLC 806
Cdd:smart00209 2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
48-70 |
8.60e-03 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 35.33 E-value: 8.60e-03
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
196-387 |
8.86e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 40.14 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 196 SPTPRAEPfsangSPQTELPPTELSVHTPSPQAEPlSPETAQTEVaprtRPAPLRHHPRAQASGTEPPSPTHSLGEGGFF 275
Cdd:NF033839 294 APKPGMQP-----SPQPEKKEVKPEPETPKPEVKP-QLEKPKPEV----KPQPEKPKPEVKPQLETPKPEVKPQPEKPKP 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 276 RASPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQgqgpwgtggTPHGPRLEPDPQhPGAWLPLLSNGPHASSLWSLF 355
Cdd:NF033839 364 EVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKP---------QPEKPKPEVKPQ-PEKPKPEVKPQPEKPKPEVKP 433
|
170 180 190
....*....|....*....|....*....|..
gi 1034559302 356 APSSPIPRCSGESEQLRacSQAPCPPEQPDPR 387
Cdd:NF033839 434 QPEKPKPEVKPQPEKPK--PEVKPQPETPKPE 463
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
509-622 |
6.30e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 111.90 E-value: 6.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 509 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 587
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1034559302 588 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 622
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
750-806 |
7.33e-16 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 72.49 E-value: 7.33e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 750 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 806
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
937-993 |
2.56e-13 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 65.55 E-value: 2.56e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 937 WYTGPWGECSSECGSGTQRRDIICVSKLGteFNVTSPSNCSHLPRPPALQPCQGQAC 993
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGG--GSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
997-1048 |
4.63e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 59.00 E-value: 4.63e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1034559302 997 WFSTPWSPCSRSCQGGTQTREVQCLSTN---QTLSTRCPPQLRPSRKRPCNSQPC 1048
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGggsIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| PLAC |
pfam08686 |
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short ... |
1056-1085 |
8.36e-11 |
|
PLAC (protease and lacunin) domain; The PLAC (protease and lacunin) domain is a short six-cysteine region that is usually found at the C terminal of proteins. It is found in a range of proteins including PACE4 (paired basic amino acid cleaving enzyme 4) and the extracellular matrix protein lacunin.
Pssm-ID: 462560 Cd Length: 31 Bit Score: 57.55 E-value: 8.36e-11
10 20 30
....*....|....*....|....*....|
gi 1034559302 1056 CKDSSPHCPLVVQARLCVYPYYTATCCRSC 1085
Cdd:pfam08686 1 CKDKFANCSLVVQARLCSHKYYRQFCCRSC 30
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
436-507 |
7.89e-10 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 57.41 E-value: 7.89e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559302 436 QGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTC 507
Cdd:pfam19236 38 QGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
809-864 |
3.26e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 53.61 E-value: 3.26e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 809 WEVGsPWSQCSVRCGRGQRSRQVRCVG-NNGDEVSEQECaSGPPQPPSREACDMGPC 864
Cdd:pfam19030 1 WVAG-PWGECSVTCGGGVQTRLVQCVQkGGGSIVPDSEC-SAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
868-931 |
8.43e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 49.76 E-value: 8.43e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034559302 868 WFHSDWSSkCSAECGTGIQRRSVVCLGSGaalgpGQGEAGagtGQSCPTGSRPPDMRACSLGPC 931
Cdd:pfam19030 1 WVAGPWGE-CSVTCGGGVQTRLVQCVQKG-----GGSIVP---DSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1000-1049 |
4.19e-06 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 44.89 E-value: 4.19e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1034559302 1000 TPWSPCSRSCQGGTQTREVQCLSTNQTLS-TRCPPQLRpsRKRPCNSQPCS 1049
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCSPPPQNGgGPCTGEDV--ETRACNEQPCP 53
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
143-392 |
5.29e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.09 E-value: 5.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 143 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 219
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 220 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 290
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 291 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 365
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809
|
250 260
....*....|....*....|....*....
gi 1034559302 366 GESEQLRA--CSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
94-416 |
2.09e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 2.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 94 ALLPRGQGPRPqtsPETLPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPgmfgygrVPFALPLHRNRR 173
Cdd:PHA03247 2616 PLPPDTHAPDP---PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQASSPPQRPRR 2685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 174 HPRSPPRSELSLISSRgeeaiPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQ-----AEPLSPETAQTEVAPRTRPAP 248
Cdd:PHA03247 2686 RAARPTVGSLTSLADP-----PPPPPTPEPAPHALVSATPLPPGPAAARQASPAlpaapAPPAVPAGPATPGGPARPARP 2760
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 249 LRHH-------PRAQASGTEPPSPTHSLGEGGFFRAS-PQPRRPSSQGWASPQVAGRRPD-------------PFPSVPR 307
Cdd:PHA03247 2761 PTTAgppapapPAAPAAGPPRRLTRPAVASLSESRESlPSPWDPADPPAAVLAPAAALPPaaspagplppptsAQPTAPP 2840
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 308 GRGQQGQGPWGTGGT--PHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPD 385
Cdd:PHA03247 2841 PPPGPPPPSLPLGGSvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ 2920
|
330 340 350
....*....|....*....|....*....|.
gi 1034559302 386 PRALQCAAFNSQEfmgqlyQWEPFTEAPLLP 416
Cdd:PHA03247 2921 PQPPPPPQPQPPP------PPPPRPQPPLAP 2945
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
809-864 |
3.11e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.57 E-value: 3.11e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559302 809 WEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDeVSEQECasgPPQPPSREACDMGPC 864
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPC---TGEDVETRACNEQPC 52
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
175-337 |
6.93e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.90 E-value: 6.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 175 PRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPR 254
Cdd:PRK07764 597 GEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGA 676
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 255 AQASGTEPPSPTHSLGEGGFFRASPQPRRPssQGWASPQVAGRRPDPfPSVPRGRGQQGQGPWGTGGTPHGPRLEPDPQH 334
Cdd:PRK07764 677 APAAPPPAPAPAAPAAPAGAAPAQPAPAPA--ATPPAGQADDPAAQP-PQAAQGASAPSPAADDPVPLPPEPDDPPDPAG 753
|
...
gi 1034559302 335 PGA 337
Cdd:PRK07764 754 APA 756
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
47-77 |
8.99e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 8.99e-05
10 20 30
....*....|....*....|....*....|.
gi 1034559302 47 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
1000-1048 |
9.94e-05 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 41.11 E-value: 9.94e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1034559302 1000 TPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLrpsRKRPCNSQPC 1048
Cdd:pfam19028 7 SEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELL---ERRPCNLPPC 52
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
100-392 |
4.53e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.54 E-value: 4.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 100 QGPRPQTSPETL-PLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 178
Cdd:PHA03247 2681 QRPRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 179 PRSElSLISSRGEEAIPSPTPRAEPFSAnGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPR---TRPAPLRHHPRA 255
Cdd:PHA03247 2761 PTTA-GPPAPAPPAAPAAGPPRRLTRPA-VASLSESRESLPSPWDPADPPAAVLAPAAALPPAASpagPLPPPTSAQPTA 2838
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 256 QASGTEPPSPTHSLG----EGGFFRASPQPRRPSSQGWASPQVAGRRPdPFPSVPRGRGQQGQGPWG-----TGGTPHGP 326
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGgsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRL-ARPAVSRSTESFALPPDQperppQPQAPPPP 2917
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559302 327 RLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPRALQCA 392
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
99-316 |
5.88e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.87 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 99 GQGPRPQTSPETLPLYRTQSRGRGGPLRGPAShlgreeTQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 178
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMS------LEEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 179 PRSElslissrgeeaiPSPTPRAEPFSANGSPQTELPPTELSvHTPSPQAEPLSPetaqtevAPRTRPAPLRHHPRAQas 258
Cdd:pfam09770 238 PQIQ------------QQQQPQQQPQQPQQHPGQGHPVTILQ-RPQSPQPDPAQP-------SIQPQAQQFHQQPPPV-- 295
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1034559302 259 gtePPSPTHSLgeggffrasPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGP 316
Cdd:pfam09770 296 ---PVQPTQIL---------QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
173-387 |
5.96e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 44.05 E-value: 5.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 173 RHPRSPPRSELSLISSRGEEAIPSPTPRAEPfsangSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHH 252
Cdd:PRK14086 76 RELGRPIRIAITVDPSAGEPAPPPPHARRTS-----EPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 253 PRAQaSGTEPPSPthslgeggfFRASPQPRR---PSSQGWASPQVAGRRPDPF-PSVPRGRGQQGQgPWGTGGTPhgprl 328
Cdd:PRK14086 151 QRPE-PGAWPRAA---------DDYGWQQQRlgfPPRAPYASPASYAPEQERDrEPYDAGRPEYDQ-RRRDYDHP----- 214
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034559302 329 EPDPQHPGAW---LPLLSNG---PHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCP-PEQPDPR 387
Cdd:PRK14086 215 RPDWDRPRRDrtdRPEPPPGaghVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPgPGEPTAR 280
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
177-387 |
1.15e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 177 SPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTE---LPPTELSVHTPSPQAEPLSPETAQtevAPRTRPAPLRHHP 253
Cdd:PHA03307 136 EMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalpLSSPEETARAPSSPPAEPPPSTPP---AAASPRPPRRSSP 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 254 RAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGPWGTG---------GTPH 324
Cdd:PHA03307 213 ISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSsrpgpasssSSPR 292
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034559302 325 GPRLEPDPQHPGAwlPLLSNGPHASSLWSLFAPSS-PIPRCSGESEqlRACSQAPCPPEQPDPR 387
Cdd:PHA03307 293 ERSPSPSPSSPGS--GPAPSSPRASSSSSSSRESSsSSTSSSSESS--RGAAVSPGPSPSRSPS 352
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
189-303 |
1.55e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.39 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 189 RGEEAIPSPTPRAEPFSANGSpqTELPPTElsvhTPSPQAEPLSPETAQTEVAPRTRPAPLRHH-PRAQASGTEPPSPTH 267
Cdd:PRK14951 383 RPEAAAPAAAPVAQAAAAPAP--AAAPAAA----ASAPAAPPAAAPPAPVAAPAAAAPAAAPAAaPAAVALAPAPPAQAA 456
|
90 100 110
....*....|....*....|....*....|....*.
gi 1034559302 268 SLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFP 303
Cdd:PRK14951 457 PETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| PTZ00441 |
PTZ00441 |
sporozoite surface protein 2 (SSP2); Provisional |
806-853 |
2.41e-03 |
|
sporozoite surface protein 2 (SSP2); Provisional
Pssm-ID: 240420 [Multi-domain] Cd Length: 576 Bit Score: 41.87 E-value: 2.41e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1034559302 806 CGHWEvgsPWSQCSVRCGRGQRSRQ-----VRCVGNNGDEVSEQECasgPPQP 853
Cdd:PTZ00441 240 CGPWD---EWTPCSVTCGKGTHSRSrpilhEGCTTHMVEECEEEEC---PVEP 286
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
697-746 |
3.39e-03 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 36.66 E-value: 3.39e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1034559302 697 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 746
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
103-340 |
4.14e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 41.21 E-value: 4.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 103 RPQTSPETLPLYRT--QSRGRGGPLRGPASHLGREETQ----EIRAARRSRLrdPIKPGMFGYGRVPFALPLHRNRRHPR 176
Cdd:PHA03378 575 QPLTSPTTSQLASSapSYAQTPWPVPHPSQTPEPPTTQshipETSAPRQWPM--PLRPIPMRPLRMQPITFNVLVFPTPH 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 177 SPPRSELSLISSRGEE-----AIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAEP--LSPETAQTEVAPRTRPAPL 249
Cdd:PHA03378 653 QPPQVEITPYKPTWTQighipYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPgrAQRPAAATGRARPPAAAPG 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 250 RHHPRAQASGTEPPsPTHSLGEGGFFRASPQPRRPSSQGWASPQvagrrPDPFPSVPRGRGQQgqgpwgtggtphgPRLE 329
Cdd:PHA03378 733 RARPPAAAPGRARP-PAAAPGRARPPAAAPGRARPPAAAPGAPT-----PQPPPQAPPAPQQR-------------PRGA 793
|
250
....*....|.
gi 1034559302 330 PDPQHPGAWLP 340
Cdd:PHA03378 794 PTPQPPPQAGP 804
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
1000-1048 |
4.26e-03 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 36.24 E-value: 4.26e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1034559302 1000 TPWSPCSRSCQGGTQTREVQCLStNQTLSTRCPPQLRpsRKRPCNSQPC 1048
Cdd:pfam00090 4 SPWSPCSVTCGKGIQVRQRTCKS-PFPGGEPCTGDDI--ETQACKMDKC 49
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
750-806 |
6.46e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 36.03 E-value: 6.46e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034559302 750 WEAGEWTSCSRSCGPGTQHRQLQCRqefgGGGSSVPPERCGHLPRpnITQSCQLRLC 806
Cdd:smart00209 2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
813-836 |
6.97e-03 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 35.86 E-value: 6.97e-03
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
188-388 |
7.40e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 40.24 E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 188 SRGEEAIPSPT--PRAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRAQASGTEPPSp 265
Cdd:PRK12323 368 SGGGAGPATAAaaPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGG- 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 266 thslgeggffRASPQPRRPSS-QGWASPQVAGRRPDPFPSVPRGRGQQGQGPwgtggtphgPRLEPDPQHPGAWLP--LL 342
Cdd:PRK12323 447 ----------APAPAPAPAAApAAAARPAAAGPRPVAAAAAAAPARAAPAAA---------PAPADDDPPPWEELPpeFA 507
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1034559302 343 SNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPRA 388
Cdd:PRK12323 508 SPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRA 553
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
192-387 |
7.60e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 40.35 E-value: 7.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 192 EAIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAE--------PLSPETAQTEVAPRTRPAPLRHHPRAQASGTEPP 263
Cdd:PRK07764 585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAapaapapaGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 264 SPTHSLGEGGffRASPQPRRPSSQGWASPQ---VAGRRPDPFPSvPRGRGQQGQGPWGTGGTPHGPRLEPDPQHPGAwLP 340
Cdd:PRK07764 665 GGDGWPAKAG--GAAPAAPPPAPAPAAPAApagAAPAQPAPAPA-ATPPAGQADDPAAQPPQAAQGASAPSPAADDP-VP 740
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1034559302 341 LLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPR 387
Cdd:PRK07764 741 LPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
48-70 |
8.60e-03 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 35.33 E-value: 8.60e-03
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
196-387 |
8.86e-03 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 40.14 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 196 SPTPRAEPfsangSPQTELPPTELSVHTPSPQAEPlSPETAQTEVaprtRPAPLRHHPRAQASGTEPPSPTHSLGEGGFF 275
Cdd:NF033839 294 APKPGMQP-----SPQPEKKEVKPEPETPKPEVKP-QLEKPKPEV----KPQPEKPKPEVKPQLETPKPEVKPQPEKPKP 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034559302 276 RASPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQgqgpwgtggTPHGPRLEPDPQhPGAWLPLLSNGPHASSLWSLF 355
Cdd:NF033839 364 EVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKP---------QPEKPKPEVKPQ-PEKPKPEVKPQPEKPKPEVKP 433
|
170 180 190
....*....|....*....|....*....|..
gi 1034559302 356 APSSPIPRCSGESEQLRacSQAPCPPEQPDPR 387
Cdd:NF033839 434 QPEKPKPEVKPQPEKPK--PEVKPQPETPKPE 463
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
48-74 |
8.92e-03 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 35.47 E-value: 8.92e-03
|
| |
