|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
39-284 |
1.62e-136 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 385.81 E-value: 1.62e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 39 APSRKFFVGGNWKMNGRKQNLGELIGTLNAAKV-PADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEI 116
Cdd:PTZ00333 1 MMKRKPFVGGNWKCNGTKASIKELIDSFNKLKFdPNNVDVVVAPPSLHIPLVQEKLKnKNFKISSQNVSLTGSGAFTGEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 117 SPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD-- 194
Cdd:PTZ00333 81 SAEMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDea 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 195 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASL 274
Cdd:PTZ00333 161 WDNIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKVGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASL 240
|
250
....*....|
gi 966970628 275 KPEFVDIINA 284
Cdd:PTZ00333 241 KPDFVDIIKS 250
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
44-283 |
2.50e-129 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 366.86 E-value: 2.50e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 44 FFVGGNWKMNGRKQNLGELIGTLNAA-KVPADTEVVCAPPTAYIDFARQKL-DPKIAVAAQNCYKVTNGAFTGEISPGMI 121
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVlKDESGVEVVVAPPFTYLAAVAEALeGSKIKVGAQNVSPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 122 KDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLA 201
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLAGVEDLAPVVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 202 YEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEaVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE-FVD 280
Cdd:cd00311 161 YEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYGE-VAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAEsFLD 239
|
...
gi 966970628 281 IIN 283
Cdd:cd00311 240 IIK 242
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
42-284 |
1.97e-119 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 342.04 E-value: 1.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 42 RKFFVGGNWKMNGRKQNLGELIGTL-NAAKVPADTEVVCAPPTAYIDFARQKL-DPKIAVAAQNCYKVTNGAFTGEISPG 119
Cdd:COG0149 2 RKPLIAGNWKMNGTLAEAKALLAALaAALADLADVEVVVCPPFTYLAAVAEALaGSPIALGAQNVHWEDSGAYTGEISAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 120 MIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTK-VIAD-NVKDWSK 197
Cdd:COG0149 82 MLKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKaALAGlSAEQAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 198 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE 277
Cdd:COG0149 162 VVIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELYGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDAE 241
|
....*...
gi 966970628 278 -FVDIINA 284
Cdd:COG0149 242 dFLAIVRA 249
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
44-284 |
2.70e-119 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 341.80 E-value: 2.70e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 44 FFVGGNWKMNGRKQNLGELIGTLNAAKVPA-DTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIK 122
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALADEsGVEVVVAPPFTYLSAVAELLGSNIKVGAQNVDPEESGAFTGEISAEMLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 123 DCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDW-SKVVLA 201
Cdd:pfam00121 81 DLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEqKNLVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 202 YEPVWAIGTGKTATPQQAQEVHEKLRGWLkSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE-FVD 280
Cdd:pfam00121 161 YEPVWAIGTGKTATPEQAQEVHAFIRAVL-AELYKEVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEdFLD 239
|
....
gi 966970628 281 IINA 284
Cdd:pfam00121 240 IINA 243
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
45-277 |
2.00e-63 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 198.49 E-value: 2.00e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 45 FVGGNWKM-NGRKQNLGELIGTLNA-AKVPADTEVVCAPPTAYIDFARQKLdpKIAVAAQNCYKVTNGAFTGEISPGMIK 122
Cdd:TIGR00419 1 LVIGNWKTyNESRGMRALEVAKIAEeVASEAGVAVAVAPPFVDLPMIKREV--EIPVYAQHVDAVLSGAHTGEISAEMLK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 123 DCGATWVVLGHSERRHVfgESDelIGQKVAHALAEGLGVIACIgekldereagiteKVVFEQTKVIAdnvkdWSKVVLAY 202
Cdd:TIGR00419 79 DIGAKGTLINHSERRMK--LAD--IEKKIARLKELGLTSVVCT-------------NNVLTTAAAAA-----LEPDVVAV 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966970628 203 EPVWAIGTGKTATPQQAQEVHEKLRgwlksnVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE 277
Cdd:TIGR00419 137 EPPELIGTGIPVSPAQPEVVHGSVR------AVKEVNESVRVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
39-284 |
1.62e-136 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 385.81 E-value: 1.62e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 39 APSRKFFVGGNWKMNGRKQNLGELIGTLNAAKV-PADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVTNGAFTGEI 116
Cdd:PTZ00333 1 MMKRKPFVGGNWKCNGTKASIKELIDSFNKLKFdPNNVDVVVAPPSLHIPLVQEKLKnKNFKISSQNVSLTGSGAFTGEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 117 SPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKD-- 194
Cdd:PTZ00333 81 SAEMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDea 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 195 WSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASL 274
Cdd:PTZ00333 161 WDNIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKVGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASL 240
|
250
....*....|
gi 966970628 275 KPEFVDIINA 284
Cdd:PTZ00333 241 KPDFVDIIKS 250
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
44-283 |
2.50e-129 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 366.86 E-value: 2.50e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 44 FFVGGNWKMNGRKQNLGELIGTLNAA-KVPADTEVVCAPPTAYIDFARQKL-DPKIAVAAQNCYKVTNGAFTGEISPGMI 121
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVlKDESGVEVVVAPPFTYLAAVAEALeGSKIKVGAQNVSPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 122 KDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLA 201
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLAGVEDLAPVVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 202 YEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEaVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE-FVD 280
Cdd:cd00311 161 YEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYGE-VAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAEsFLD 239
|
...
gi 966970628 281 IIN 283
Cdd:cd00311 240 IIK 242
|
|
| PLN02561 |
PLN02561 |
triosephosphate isomerase |
41-284 |
2.68e-124 |
|
triosephosphate isomerase
Pssm-ID: 178175 Cd Length: 253 Bit Score: 354.90 E-value: 2.68e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 41 SRKFFVGGNWKMNGRKQNLGELIGTLNAAKVPA--DTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISP 118
Cdd:PLN02561 2 ARKFFVGGNWKCNGTVEEVKKIVTTLNEAEVPSedVVEVVVSPPFVFLPLVKSLLRPDFQVAAQNCWVKKGGAFTGEISA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 119 GMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKV 198
Cdd:PLN02561 82 EMLVNLGIPWVILGHSERRALLGESNEFVGDKVAYALSQGLKVIACVGETLEQRESGSTMDVVAAQTKAIADKVSDWANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 199 VLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEF 278
Cdd:PLN02561 162 VLAYEPVWAIGTGKVATPAQAQEVHDELRKWLHKNVSPEVAATTRIIYGGSVTGANCKELAAQPDVDGFLVGGASLKPEF 241
|
....*.
gi 966970628 279 VDIINA 284
Cdd:PLN02561 242 IDIIKS 247
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
42-284 |
1.97e-119 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 342.04 E-value: 1.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 42 RKFFVGGNWKMNGRKQNLGELIGTL-NAAKVPADTEVVCAPPTAYIDFARQKL-DPKIAVAAQNCYKVTNGAFTGEISPG 119
Cdd:COG0149 2 RKPLIAGNWKMNGTLAEAKALLAALaAALADLADVEVVVCPPFTYLAAVAEALaGSPIALGAQNVHWEDSGAYTGEISAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 120 MIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTK-VIAD-NVKDWSK 197
Cdd:COG0149 82 MLKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKaALAGlSAEQAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 198 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE 277
Cdd:COG0149 162 VVIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELYGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDAE 241
|
....*...
gi 966970628 278 -FVDIINA 284
Cdd:COG0149 242 dFLAIVRA 249
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
44-284 |
2.70e-119 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 341.80 E-value: 2.70e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 44 FFVGGNWKMNGRKQNLGELIGTLNAAKVPA-DTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIK 122
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALADEsGVEVVVAPPFTYLSAVAELLGSNIKVGAQNVDPEESGAFTGEISAEMLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 123 DCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDW-SKVVLA 201
Cdd:pfam00121 81 DLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEqKNLVIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 202 YEPVWAIGTGKTATPQQAQEVHEKLRGWLkSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE-FVD 280
Cdd:pfam00121 161 YEPVWAIGTGKTATPEQAQEVHAFIRAVL-AELYKEVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEdFLD 239
|
....
gi 966970628 281 IINA 284
Cdd:pfam00121 240 IINA 243
|
|
| tpiA |
PRK00042 |
triosephosphate isomerase; Provisional |
42-284 |
2.26e-114 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 234589 Cd Length: 250 Bit Score: 329.39 E-value: 2.26e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 42 RKFFVGGNWKMNGRKQNLGELIGTLNAA-KVPADTEVVCAPPTAYIDFARQKLDP-KIAVAAQNCYKVTNGAFTGEISPG 119
Cdd:PRK00042 1 RKPIIAGNWKMNKTLAEAKALVEELKAAlPDADGVEVAVAPPFTALASVKEALKGsNIKLGAQNVHPEDSGAFTGEISAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 120 MIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNV--KDWSK 197
Cdd:PRK00042 81 MLKDLGVKYVIIGHSERRQYFGETDELVNKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLEAALAGLsaEQFAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 198 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEaVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE 277
Cdd:PRK00042 161 LVIAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYGE-VAEKVRILYGGSVKPDNAAELMAQPDIDGALVGGASLKAE 239
|
....*...
gi 966970628 278 -FVDIINA 284
Cdd:PRK00042 240 dFLAIVKA 247
|
|
| PLN02429 |
PLN02429 |
triosephosphate isomerase |
34-284 |
5.43e-101 |
|
triosephosphate isomerase
Pssm-ID: 166070 Cd Length: 315 Bit Score: 297.86 E-value: 5.43e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 34 GSIAMAPSRKFFVGGNWKMNGRKQNLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFT 113
Cdd:PLN02429 56 GVVAMAGSGKFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTDRIDISGQNSWVGKGGAFT 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 114 GEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVK 193
Cdd:PLN02429 136 GEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVP 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 194 DWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGAS 273
Cdd:PLN02429 216 SWDNIVVAYEPVWAIGTGKVASPQQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGAS 295
|
250
....*....|..
gi 966970628 274 LK-PEFVDIINA 284
Cdd:PLN02429 296 LKgPEFATIVNS 307
|
|
| PRK13962 |
PRK13962 |
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional |
30-284 |
4.63e-84 |
|
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional
Pssm-ID: 237572 [Multi-domain] Cd Length: 645 Bit Score: 264.67 E-value: 4.63e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 30 LQRLGSIAMAPSRKFFVGGNWKMNGRKQNLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLD-PKIAVAAQNCYKVT 108
Cdd:PRK13962 385 LPGIACLLDKNPRKPIIAGNWKMNKTPAEAKEFVNELKKYVKDAQAEVVVCPPFTALPSVKEAVDgSNIKLGAQNVFYEE 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 109 NGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTK-- 186
Cdd:PRK13962 465 KGAYTGEISGPMLAEIGVEYVIIGHSERRQYFGETDELVNKKVLAALKAGLTPILCVGETLDERESGITFDVVRLQLKaa 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 187 ---VIADNVKdwsKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPD 263
Cdd:PRK13962 545 lngLSAEQVK---KVVIAYEPVWAIGTGKVATPEQAQEVHAFIRKLVAELYGEEAARKVRILYGGSVKSENAAGLFNQPD 621
|
250 260
....*....|....*....|..
gi 966970628 264 VDGFLVGGASLKP-EFVDIINA 284
Cdd:PRK13962 622 IDGGLVGGASLKAqEFAAIANY 643
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
45-277 |
2.00e-63 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 198.49 E-value: 2.00e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 45 FVGGNWKM-NGRKQNLGELIGTLNA-AKVPADTEVVCAPPTAYIDFARQKLdpKIAVAAQNCYKVTNGAFTGEISPGMIK 122
Cdd:TIGR00419 1 LVIGNWKTyNESRGMRALEVAKIAEeVASEAGVAVAVAPPFVDLPMIKREV--EIPVYAQHVDAVLSGAHTGEISAEMLK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 123 DCGATWVVLGHSERRHVfgESDelIGQKVAHALAEGLGVIACIgekldereagiteKVVFEQTKVIAdnvkdWSKVVLAY 202
Cdd:TIGR00419 79 DIGAKGTLINHSERRMK--LAD--IEKKIARLKELGLTSVVCT-------------NNVLTTAAAAA-----LEPDVVAV 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 966970628 203 EPVWAIGTGKTATPQQAQEVHEKLRgwlksnVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE 277
Cdd:TIGR00419 137 EPPELIGTGIPVSPAQPEVVHGSVR------AVKEVNESVRVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| PRK14565 |
PRK14565 |
triosephosphate isomerase; Provisional |
44-282 |
1.73e-55 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 237758 Cd Length: 237 Bit Score: 179.18 E-value: 1.73e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 44 FFVGGNWKMNGRKQNLGELIGTLNA--AKVPADTEVVCAPP----TAYIDfarqkLDPKIAVAAQNCYKVTNGAFTGEIS 117
Cdd:PRK14565 3 FLIVANWKMNGDFSLFSSFLKELSNklANNEITLKLVICPPftamSSFVE-----CNPNIKLGAQNCFYGSSGGYTGEIS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 118 PGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKviaDNVKDWSK 197
Cdd:PRK14565 78 AKMLKECGCSYVILGHSERRSTFHETDSDIRLKAESAIESGLIPIICVGETLEDRENGMTKDVLLEQCS---NCLPKHGE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 198 VVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWlksnvseavAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPE 277
Cdd:PRK14565 155 FIIAYEPVWAIGGSTIPSNDAIAEAFEIIRSY---------DSKSHIIYGGSVNQENIRDLKSINQLSGVLVGSASLDVD 225
|
....*.
gi 966970628 278 -FVDII 282
Cdd:PRK14565 226 sFCKII 231
|
|
| PRK14905 |
PRK14905 |
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ... |
41-270 |
7.41e-41 |
|
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional
Pssm-ID: 184898 [Multi-domain] Cd Length: 355 Bit Score: 144.79 E-value: 7.41e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 41 SRKFFVGGNWKM---NGRK-QNLGELIGTLNAAKVPADTEVVCAPptAYIDF-------ARQKLDPKIAVAAQNCYKVTN 109
Cdd:PRK14905 2 AKKIYFGTNLKMykgNAETvDYLSELLAFAEKFKSDYDIELFVIP--SYIALkdaveaaASETGHPKIKIGAQNMNAKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 110 GAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIA 189
Cdd:PRK14905 80 GQFTGEISPLMLKELGIELVMIGHSERRHVLKETDQEENEKVLAALKHGFITLLCIGETLEQKNYNISDEVLRTQLKIGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 190 DNV--KDWSKVVLAYEPVWAIGTGKT-ATPQQAQEVHEKLRGWLKSNVSEAvAQSTRIIYGGSVTGATCKELASQPDVDG 266
Cdd:PRK14905 160 HGVsaEQLPHLFIAYEPVWAIGEGGIpASAEYADEKHAIIKQCLFELFAEE-SKKIPVLYGGSVNLENANELIMKPHIDG 238
|
....
gi 966970628 267 FLVG 270
Cdd:PRK14905 239 LFIG 242
|
|
| PRK15492 |
PRK15492 |
triosephosphate isomerase; Provisional |
41-270 |
1.64e-39 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 185389 Cd Length: 260 Bit Score: 138.59 E-value: 1.64e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 41 SRKFFVGGNWKM-NGRKQ------NLGELIGTLNAAKvpaDTEVVCAPPTAYIDFARQKL-----DPKIAVAAQNCYKVT 108
Cdd:PRK15492 1 MKKIYFGTNLKMyKGIADatdflaKLSELADDIPADK---DIELFVIPSFTAIQDAIAATlaiphDHPIIIGAQNMNPND 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 109 NGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKV- 187
Cdd:PRK15492 78 NGQFTGDISPLMLKEIGTQLVMIGHSERRHKFGETDQEENAKVLAALKHDFTTLLCVGETLEQKNYGISDEILRTQLKIg 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 188 -IADNVKDWSKVVLAYEPVWAIGT-GKTATPQQAQEVHEKLRGWLKSNVSEAvAQSTRIIYGGSVTGATCKELASQPDVD 265
Cdd:PRK15492 158 lHGINPDQLAKLRIAYEPVWAIGEaGIPASADYADEKHAVIKQCLIELFGDA-GDDIPVFYGGSVNAENANELFGQPHID 236
|
....*
gi 966970628 266 GFLVG 270
Cdd:PRK15492 237 GLFIG 241
|
|
| PRK04302 |
PRK04302 |
triosephosphate isomerase; Provisional |
68-164 |
2.49e-09 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 235274 Cd Length: 223 Bit Score: 56.03 E-value: 2.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966970628 68 AAKVPADTEV--VCAPPTAYIDFARQKLDpkIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGEsde 145
Cdd:PRK04302 28 AEKVSKETGVriAVAPQALDIRRVAEEVD--IPVYAQHVDPVEPGSHTGHILPEAVKDAGAVGTLINHSERRLTLAD--- 102
|
90
....*....|....*....
gi 966970628 146 lIGQKVAHALAEGLGVIAC 164
Cdd:PRK04302 103 -IEAVVERAKKLGLESVVC 120
|
|
| |
