NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|966969435|ref|XP_015005841|]
View 

inward rectifier potassium channel 4 [Macaca mulatta]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
IRK_C pfam17655
Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has ...
185-357 5.65e-110

Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has an Ig fold.


:

Pssm-ID: 465439  Cd Length: 174  Bit Score: 321.46  E-value: 5.65e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435  185 LLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHE 264
Cdd:pfam17655   1 LKFSKNAVICQRDGKLCLMFRVGDLRKSHLIEAHVRAQLLKTRVTKEGEVIPLYQVDLDLGVDTGSDRIFLVWPLTVYHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435  265 IDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKS-HYKVDYSRFHKTYEVA 343
Cdd:pfam17655  81 IDEDSPLYDLSAKDLLEEDFELVVILEGTVESTGMTTQARTSYLPEEILWGHRFEPVISYSKEgRYVVDYSNFDKTVEVP 160
                         170
                  ....*....|....
gi 966969435  344 gTPCCSARELQESK 357
Cdd:pfam17655 161 -TPHCSAKELDEKK 173
IRK pfam01007
Inward rectifier potassium channel transmembrane domain;
22-178 1.16e-81

Inward rectifier potassium channel transmembrane domain;


:

Pssm-ID: 460023  Cd Length: 141  Bit Score: 247.87  E-value: 1.16e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435   22 VKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPGaggpaa 101
Cdd:pfam01007   1 VSKNGHCNVVFTNIPEKSLRYLQDIFTTLVDLKWRYMLLLFSLSFVLSWLIFGLIWYLIAYSHGDLDQRPDDGH------ 74
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966969435  102 gsggaapaapKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
Cdd:pfam01007  75 ----------TPCVYNVHSFTSAFLFSIETQTTIGYGFRYVTEECPEAIFLLVFQSIVGCLIDAFMIGIVFAKMARP 141
 
Name Accession Description Interval E-value
IRK_C pfam17655
Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has ...
185-357 5.65e-110

Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has an Ig fold.


Pssm-ID: 465439  Cd Length: 174  Bit Score: 321.46  E-value: 5.65e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435  185 LLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHE 264
Cdd:pfam17655   1 LKFSKNAVICQRDGKLCLMFRVGDLRKSHLIEAHVRAQLLKTRVTKEGEVIPLYQVDLDLGVDTGSDRIFLVWPLTVYHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435  265 IDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKS-HYKVDYSRFHKTYEVA 343
Cdd:pfam17655  81 IDEDSPLYDLSAKDLLEEDFELVVILEGTVESTGMTTQARTSYLPEEILWGHRFEPVISYSKEgRYVVDYSNFDKTVEVP 160
                         170
                  ....*....|....
gi 966969435  344 gTPCCSARELQESK 357
Cdd:pfam17655 161 -TPHCSAKELDEKK 173
IRK pfam01007
Inward rectifier potassium channel transmembrane domain;
22-178 1.16e-81

Inward rectifier potassium channel transmembrane domain;


Pssm-ID: 460023  Cd Length: 141  Bit Score: 247.87  E-value: 1.16e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435   22 VKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPGaggpaa 101
Cdd:pfam01007   1 VSKNGHCNVVFTNIPEKSLRYLQDIFTTLVDLKWRYMLLLFSLSFVLSWLIFGLIWYLIAYSHGDLDQRPDDGH------ 74
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966969435  102 gsggaapaapKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
Cdd:pfam01007  75 ----------TPCVYNVHSFTSAFLFSIETQTTIGYGFRYVTEECPEAIFLLVFQSIVGCLIDAFMIGIVFAKMARP 141
 
Name Accession Description Interval E-value
IRK_C pfam17655
Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has ...
185-357 5.65e-110

Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has an Ig fold.


Pssm-ID: 465439  Cd Length: 174  Bit Score: 321.46  E-value: 5.65e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435  185 LLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHE 264
Cdd:pfam17655   1 LKFSKNAVICQRDGKLCLMFRVGDLRKSHLIEAHVRAQLLKTRVTKEGEVIPLYQVDLDLGVDTGSDRIFLVWPLTVYHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435  265 IDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKS-HYKVDYSRFHKTYEVA 343
Cdd:pfam17655  81 IDEDSPLYDLSAKDLLEEDFELVVILEGTVESTGMTTQARTSYLPEEILWGHRFEPVISYSKEgRYVVDYSNFDKTVEVP 160
                         170
                  ....*....|....
gi 966969435  344 gTPCCSARELQESK 357
Cdd:pfam17655 161 -TPHCSAKELDEKK 173
IRK pfam01007
Inward rectifier potassium channel transmembrane domain;
22-178 1.16e-81

Inward rectifier potassium channel transmembrane domain;


Pssm-ID: 460023  Cd Length: 141  Bit Score: 247.87  E-value: 1.16e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966969435   22 VKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPGaggpaa 101
Cdd:pfam01007   1 VSKNGHCNVVFTNIPEKSLRYLQDIFTTLVDLKWRYMLLLFSLSFVLSWLIFGLIWYLIAYSHGDLDQRPDDGH------ 74
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966969435  102 gsggaapaapKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARP 178
Cdd:pfam01007  75 ----------TPCVYNVHSFTSAFLFSIETQTTIGYGFRYVTEECPEAIFLLVFQSIVGCLIDAFMIGIVFAKMARP 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure