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Conserved domains on  [gi|966956405|ref|XP_014999877|]
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ataxin-3 isoform X4 [Macaca mulatta]

Protein Classification

ataxin-3 family protein( domain architecture ID 11244366)

ataxin-3 (ATXN3) family protein similar to Homo sapiens ataxin-3 and ataxin-3-like protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SUIM_assoc pfam16619
Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on ...
 142-207 1.43e-24

Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on Ataxin 3 proteins that lies immediately C-terminal to the second UIM domain linking it to a third when present. The function is not known. It is rich in glutamine residues.


:

Pssm-ID: 465203  Cd Length: 60  Bit Score: 92.25  E-value: 1.43e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966956405  142 NISQDIPQTSGTNLTSEELRKRREAYFEKQQQQQKQQqqqqqgDLSGQSSHPCERPTTSSGALGSD 207
Cdd:pfam16619   1 NISQDVPQTSGTSLTSEELRKRREAYFEKQQQQQQQL------DQPGQSSHPHERPTTSSGALGSD 60
Josephin super family cl20229
Josephin;
9-42 4.01e-16

Josephin;


The actual alignment was detected with superfamily member pfam02099:

Pssm-ID: 460444  Cd Length: 154  Bit Score: 73.03  E-value: 4.01e-16
                          10        20        30
                  ....*....|....*....|....*....|....
gi 966956405    9 WFNLNSLLTGPELISDTYLALFLAQLQQEGYSIF 42
Cdd:pfam02099 121 WYNLNSLLKAPELISDTYLSAFLDQLEAEGYSIF 154
 
Name Accession Description Interval E-value
SUIM_assoc pfam16619
Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on ...
 142-207 1.43e-24

Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on Ataxin 3 proteins that lies immediately C-terminal to the second UIM domain linking it to a third when present. The function is not known. It is rich in glutamine residues.


Pssm-ID: 465203  Cd Length: 60  Bit Score: 92.25  E-value: 1.43e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966956405  142 NISQDIPQTSGTNLTSEELRKRREAYFEKQQQQQKQQqqqqqgDLSGQSSHPCERPTTSSGALGSD 207
Cdd:pfam16619   1 NISQDVPQTSGTSLTSEELRKRREAYFEKQQQQQQQL------DQPGQSSHPHERPTTSSGALGSD 60
Josephin pfam02099
Josephin;
9-42 4.01e-16

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 73.03  E-value: 4.01e-16
                          10        20        30
                  ....*....|....*....|....*....|....
gi 966956405    9 WFNLNSLLTGPELISDTYLALFLAQLQQEGYSIF 42
Cdd:pfam02099 121 WYNLNSLLKAPELISDTYLSAFLDQLEAEGYSIF 154
 
Name Accession Description Interval E-value
SUIM_assoc pfam16619
Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on ...
 142-207 1.43e-24

Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on Ataxin 3 proteins that lies immediately C-terminal to the second UIM domain linking it to a third when present. The function is not known. It is rich in glutamine residues.


Pssm-ID: 465203  Cd Length: 60  Bit Score: 92.25  E-value: 1.43e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 966956405  142 NISQDIPQTSGTNLTSEELRKRREAYFEKQQQQQKQQqqqqqgDLSGQSSHPCERPTTSSGALGSD 207
Cdd:pfam16619   1 NISQDVPQTSGTSLTSEELRKRREAYFEKQQQQQQQL------DQPGQSSHPHERPTTSSGALGSD 60
Josephin pfam02099
Josephin;
9-42 4.01e-16

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 73.03  E-value: 4.01e-16
                          10        20        30
                  ....*....|....*....|....*....|....
gi 966956405    9 WFNLNSLLTGPELISDTYLALFLAQLQQEGYSIF 42
Cdd:pfam02099 121 WYNLNSLLKAPELISDTYLSAFLDQLEAEGYSIF 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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